GOOD AFTERNOON.
GOOD MORNING.
MY NAME IS THERESA CRUZ.
I HAVE THE HONOR AND PRIVILEGE
OF DIRECTING THE NATIONAL CENTER
FOR MEDICAL REHABILITATION
RESEARCH AT NICHD AND I WANT TO
THANK YOU ALL FOR JOINING US
TODAY FOR THIS WEBINAR ABOUT OUR
EARLY CAREER RESEARCH RO3
FUNDING OPPORTUNITY.
TODAY WE'RE GOING TO HEAR FROM
MARIA NURMINSKAYA, WHO IS THE
PROGRAM OFFICER IN CHARGE OF
THIS PROGRAM.
SHE IS A LITTLE UNDERTHE WEATHER
SO I'M -- UNDER THE WEATHER SO
I'M TRYING TO GIVE HER AS MUCH
TIME TO EASE HER THROAT AS
POSSIBLE SO WE WON'T ASK HER TO
SPEAK ANYMORE THAN SHE NEEDS TO
BUT I'M SUPER THRILLED TO HAVE
HER AS A MEMBER OF OUR CENTER
FOR THE LAST FEW YEARS AND HER
LEADERSHIP ON THIS PROGRAM.
WE ALSO HAVE OUR PROGRAM ANALYST
CHRIS HUGHES WHO HELPED PULL
THIS TOGETHER BOTH LOOKING AT
SOME DATA AND PULLING TOGETHER
THE SLIDES FOR TODAY.
SO THE 2 OF US ARE HERE TO
SUPPORT MARIA.
I WOULD ASK THAT ALL QUESTIONS
BE PUT IN THE Q&A BOX.
YOU SHOULD ALL HAVE ACCESS TO
THAT AND WE DO EXPECT TO HAVE
PLENTY OF TIME FOR Q&A AT THE
END OF THE PRESENTATION.
WITH THAT I WILL TURN IT OVER TO
MARIA AND WE COULD HAVE HER
SLIDES, THANK YOU.
>> THANK YOU THERESA FOR THE
INTRODUCTION.
LET ME TRY TO SHARE MY SCREEN.
GOOD, NO?
>> LOOKS GOOD, THANK YOU.
>> OKAY, THANK YOU.
SO A LOT OF APREV BRAIGZS --
ABBREVIATIONS, -- WELCOME FIRST
OF ALL.
NIH USES A LOT OF ABBREVIATIONS
AND THIS PROGRAM IS SUPPORTED BY
THE NATIONAL CENTER FOR MEDICAL
REHABILITATION RESEARCH, WHICH
IS ABBREVIATED TO NCMRR, AND
EARLY CAREER RESEARCH AND
SHORTENED TO ECR AND YOU WILL
SEE THAT ON THE SLIDE AND OUR
THEME IS GENERAL FUNDING
MECHANISM AT NIH.
SO THE CURRENT FUNDING
OPPORTUNITY ANNOUNCEMENT IS UP
HERE, P A R-25-124, IF YOU ARE
CONSIDERING APPLYING FOR THIS
AWARD, I WILL BRIEFLY WALK YOU
THROUGH MAIN POINTS THAT YOU
WOULD LIKE TO EMPHASIZE FOR YOU
WHEN YOU'RE SUBMITTING YOUR
APPLICATIONS.
SO THIS FUNDING MECHANISM
SUPPORTS BOTH BASIC AND CLINICAL
RESEARCH.
DEVELOPED FOR SCIENTISTS IN
THEIR DEPENDENT RESEARCH
CAREERS.
WE CONSIDER THIS TO BE QUITE
GENEROUS WHEN YOU OFFER UP TO
200,000 IN DIRECT COSTS OVER 2
YEARS BUT OUR RO3 MECHANISM IS
SHORT-TERM, 2 YEAR MECHANISM SO
WE ARE LOOKING FOR PROJECTS THAT
CAN REALISTICALLY BE COMPLETE
INDEED 2 YEARS AND THAT FOCUS ON
OBTAINING SUFFICIENT PRELIMINARY
DATA FOR A SUBSEQUENT RO-1
APPLICATION.
NOW WE HAVE 3 SUBMISSION CYCLES
PER YEAR AND THEY WILL HELP YOU
TO SUBMIT AND SUCCEED AND OBTAIN
THIS AWARD.
TO BE A PRINCIPAL INVESTIGATOR
FOR THIS AWARD, YOU MUST BE AN
INDEPENDENT INVESTIGATOR, NO
OTHER DOCTORAL FELLOW AT THE
TIME OF SUBMISSION.
YOU BE NO MORE THAN 8 YEARS
BEYOND THE DATE THAT FIRST
PROFESSION, ADVANCED
PROFESSIONAL OR TERMINAL
ACADEMIC DEGREE WAS AWARDED SUCH
AS Ph.D.
ATTAINMENT OF AN ADDITIONAL
MYSTERIER'S DEGREE AFTER RECEPT
OF A DOCTORAL LEVEL DID NOT
EXTEND THE TIMELINE.
PLEASE NOTE THAT THESE
RESTRICTIONS ARE IN THE WINDOW
OF 8 YEARS, AND SO WHEN PLANNING
YOUR RESUBMISSION PROCESS PLEAE
ACCOUNT THAT RARELY IT IS FUNDED
ON THE FIRST ATTEMPT AND YOU
MOST LIKELY WILL -- PLAN IF YIEW
ARE WITHIN 8 YEARS OF YOUR
PROGRAM.
FOLLOWING FORMAL YEARS OF
CLINICAL TRAINING, ARE NOT
COUNTED AS PART OF THE 8 YEAR
LIMIT.
IF YOU HAVE ANY QUESTIONS OR
CONCERNS OR YOU WANT TO DISCUSS
WITH ME WHETHER ELIGIBILITY CAN
BE EXTENDED IN THE PROGRAM.
PEOPLE WHO ARE NOT ELIGE TO
APPLY, ARE INDIVIDUALS WHO AT
THE TIME OF SUBMISSION HAVE
SERVED AS PRINCIPAL
INVESTIGATORS OR PEER REVIEWED
NIH RESEARCH AWARD, OVER 100,000
IN DIRECT COSTS PER YEAR IN
OTHER WORDS AN RO-1, OR HAVE
SERVED AS PRINCIPLE
INVESTIGATORS ON NONNETWORK IH
RESEARCH GRANTS WITH OVER
150,000 TOTAL COSTS PER YEAR.
ALSO PROJECT LEADERS ON
SUBPROGGENTS OF PO1 OR P50
GRANTS ARE NOT ELIGIBLE, AND
RECIPIENTS OF THE NIH K99/R00
AWARD ARE NOT ELIGIBLE.
THE RESEARCH MUST BE FOCUSED ON
1 OR MORE OF THE AREAS WITHIN
THE MISSION OF NCMRR.
SO I LIST HERE THE 6 TOPICS AND
IF YOU GO TO THIS SITE, YOU WILL
SEE EXAMPLES OF PROJECTS FUNDED
UNDER THESE FOCUS AREAS, SO YOU
CAN UNDERSTAND BETTER WHAT IS
NCMRR FUNDING.
WE HAVE DEFINED 3 AREAS WHICH
ARE NONRESPONSIVE TO THESE AND
WILL BE WITHDRAWN PRIOR TO
REVIEW.
FIRST IS COGNITIVE REHABILATION
WITHOUT A PHYSICAL
REHABILITATION COMPONENT.
SECOND, IS SPORTS MEDICINE FOR
REHABILITATION FOR PEOPLE
WITHOUT PHYSICAL DISABILITIES
SUCH AS ABLED BODIES ATHLETES OR
RECOVERY AND PREVENTION OF
INJURIES RELATED TO SPORTS AND
EXERCISE BY PEOPLE WITHOUT
PHYSICAL DISABILITIES.
AND ALSO WE WILL NOT FUND UNDER
THIS FUNDING ANNOUNCE WANT,
QUEPMENT OF ANIMAL MODELS FOR
DISEASES OR INJURY CONDITIONS.
WE DO ALLOW CLINICAL TRIALS FOR
THIS AWARD, BUT ONLY THE EARLY
STAGE CLINICAL TRIALS SUCH AS
FIRST IN HUMAN TESTING,
EVALUATION OF SAFETY AND
FEASIBILITY OF THE INTERVENTION,
NO LARGE CLINICAL TRIALS ARE
SUPPORTED BY THIS MECHANISM.
SO THE MAIN POINTS TO KEEP IN
MIND WHEN YOU'RE CONSIDERING
THIS AWARD IS REEMILYINARY DATA
ARE NOT QUITE WHAT IT IS
EXPECTED HOWEVER, IF AVAILABLE,
IT IS ALLOWED TO INCLUDE
PRELIMINARY DATA IN MECHANISM,
MAKE SURE THIS DATA IS SUITABLE
FOR THE APPLICATION.
RESULTS DERIVED FROM THIS
PROJECT SHOULD LIKELY BE
SUITABLE AS PRELIMINARY DATA FOR
SUBSEQUENT RO-1 APPLICATION
EMPLOY AND A NOTE, A 1-PAGE
ATTACHMENT TITLED PLAN FOR
INCLUSION OF PEOPLE WITH LIVED
EXPERIENCES PIPLE, MUST BE
INCLUDED.
THANK YOU.
SO THE PEOPLE FILE, PEOPLE PLAN
SHOULD INCLUDE PEOPLE WITH LIVED
EXPERIENCES AS KEY PERSONNEL,
COLLABORATORS, MEMBERS OF FOCUS
GROUPS, COMMUNITY ENGAGEMENT
BOARDS AND WE REALLY ENCOURAGE
YOU TO CONTACT THE LIVED
EXPERIENCES TO VERY EARLY IN
PLANNING YOUR RESEARCH, AND
THESE PATIENT INFORMS THE
SPECIFIC AIMS OF VERIFICATION.
IT'S SOMETIMES WE SEE THAT
PEOPLE DESIGN PRODUCTS BUT NEVER
ASK USERS IF THIS PRODUCT IS
SIGNIFICANT.
FOR BASIC SCIENCE PROJECTS NOT
DIRECTLY INVOLVING PEOPLE WITH
LIVES EXPERIENCE, A PLAN TO
INFORM FUTURE TRANSLATION AND/OR
CLINICAL PERSPECTIVE IS
APPROPRIATE.
THIS PLAN FOR INCLUSION OF
PEOPLE WITH LIVED EXPERIENCES
WILL BE CONSIDERED AS PART OF
THE SCIENTIFIC AND TECHNICAL
PEER REVIEW AS WELL AS THE
PROGRAMMATIC REVIEW WHEN MAKING
FINANCIAL DECISIONS.
SO WE HAVE NOTED COMMON MISTAKES
WHEN PEOPLE SUBMIT APPLICATIONS
IN RESPONSE TO THIS FUNDING
OPPORTUNITY ANNOUNCEMENT AND
QUITE OFTEN UNFORTUNATELY WE SEE
THAT PEOPLE FORGET TO PLAN FOR
THIS.
IF IT HAPPENS THE APPLICATION IS
WITHDRAWN FROM CONSIDER PRIOR TO
REVIEW.
THE SECOND MOST COMMON PROBLEM
FOR WITHDRAWAL OF THE
PUBLICATION REVIEW, IS
MISCLASSIFIED CLINICAL TRIAL
STUDY.
IF YOUR PROJECT IS DETERMINED BY
US, THE PROGRAM TO BE A CLINICAL
TRIAL, BUT YOU AS A PI DID NOT
INDICATE IT IN THE APPLICATION,
THE APPLICATION WILL BE
WITHDRAWN.
AND THOUGH WE HAVE SEVERAL
LEVELS OF CHECK POINTS TO
IDENTIFY THIS CLASSIFIED
CLINICAL TRIALS, SOMETIMES IF
THEY STILL FALL IN GAPS AND GET
REVIEW AND SOMETIMES EVEN GET
GOOD SCORES BUT THEN WE'RE STILL
REJECTING FUNDING THESE THIS
APPLICATIONS.
SO THIS IS VERY SAD STORY, CAN
BE.
SO TO UNDERSTAND WHAT QUALIFIES
AS A CLINICAL TRIAL UNDER THE
NIH GUIDELINES, PLEASE REVIEW
THIS LINK, IT'S FROM THE SLIDES
BEING SHARED WITH YOU.
BUT BASICALLY NIH DEFINES
CLINICAL TRIALS VERY BROADLY.
ANSWERING QUESTIONS WHEN
DECIDING WHETHER YOUR STUDY IS A
CLINICAL TRIAL BY NIH
DEFINITION.
FIRST DOES THE STUDY INVOLVE 1
OR MORE HUMAN SUBJECTS, EVEN 1
SUBJECT COULD BE OKAY.
SECOND, DO THE HUMAN SUBJECTS
RECEIVE INTERVENTIONS?
SOMETIMES PRINCIPLE
INVESTIGATORS ARGUE THAT
EXPERIMENTAL CONDITIONS ARE NOT
INTERVENTIONS BUT USUALLY IF
ANYTHING WE DO IS BEYOND REGULAR
CLINICAL CARE, THIS WOULD BE
CONSIDERED AN INTERVENTION.
EVAL UTR THE EECT OF
INTERVENTIONS ON THE HUMAN
SUBJECTS AND DO THE OUTCOMES
HEALTH RELATED BIOMEDICAL OR
BEHAVIORIAL OUTCOMES?
THIS IS VERY IMPORTANT.
SO MOST STUDIES INVOLVED IN THIS
SUBJECT COULD BE CONSIDERED A
CLINICAL TRIAL.
AGAIN, HERE IS A LINK TO THE
DECISION TREE, AND PLEASE USE IT
NOT TO WASTE TIME PREPARING IN
THIS WEBSITE, CLINICAL TRIAL
APPLICATION THAT WILL BE
WITHDRAWN.
YOU PROBABLY HAVE HEARD ABOUT
THE WORK WHICH WILL TAKE PLACE
AT THE END OF JANUARY, NEXT
WEEK, SO IF IT DOESN'T COMPARE
YOUR APPLICATION BUT INSTEAD OF
5 COURSE, THOSE ASSIGNED TO THE
APPLICATION, KNOW THERE WILL
ONLY BE 2 CRITERIA SCORES
ASSIGNED THEY'RE NOW CALLED
IMPACT SCORES, IT'S THE
IMPORTANCE OF RESEARCH WHICH
COMBINES THE PREVIOUS
CONSIDERATION OF INVESTIGATION
AND FACTOR TO IS THE RIGOR AND
FEASIBILITY TO THE STRENGTHS AND
WEAKNESSES OF THE APPROACH, AND
FACTOR 3 IS NOT SCORED BUT IT
WILL COUNT FOR INVESTIGATORS AND
ENVIRONMENT EMPLOY SO BASICALLY
THE REVIEWERS ARE ASKED ONLY TO
IDENTIFY IF THE EXPERTISE OF THE
SEARCH TEAM ARE APPROPRIATE TO
PERFORM THE PROPOSED STUDY OR IF
THERE ARE GIFTS IDENTIFIED
MISSING BUT SOME IMPORTANT FIELD
OF EXPERTISE ON THE TEAM THEN,
IT SHOULD BE NOTED ALSO.
THERE ARE FOR CLINICAL TRIALS,
YOU WILL NEED TO PRESENT A
TIMELINE AND THIS WILL BE
EVALUATED FOR A CLINICAL TRIAL,
AND THE REVIEWERS WILL ALSO
COMMENTOT INCLUSION PLANS,
INCLUSION, WOMEN, MINORITIES AND
CHILDREN.
ADDITIONAL CRITERIA THAT ARE NOT
SCORED FOR THE SCORES INCLUDE
NEW SUBJECT PROTECTION, HUMAN
SUBJECT PROTECTIONS, IF YOU USE
HUMAN SUBJECTS IN YOUR STUDY
THEN YOU NEED TO PROVIDE HUMAN
SUBJECT PROTECTION PLAN EMPLOY
WORKING WITH ANIMAL PROTECTION,
IF YOU ARE WORKING WITH ANIMALS.
BIOHAZARDS AND RESUBMISSION AND
RENEWAL, REVISION, THIS IS
GENERAL TERMS FOR OUR PURPOSE,
FOR OUR FUNDING MECHANISM AND
SEE IF OUR CRR3, WE CAN ONLY
TALK ABOUT THESE SUBMISSIONS,
THIS IS NOT REMOVAL AND THERE'S
NO REVISION FOR THIS TYPE OF
AWARD.
SO GRANTSMANSHIP IS AN ART WHICH
YOU LEARN BY DOING IT.
AND THERE IS A LOT OF MATERIALS
POSTED BY NIH, A PODCAST,
YouTUBE, WHERE YOU CAN GET
SOME TIPS ON HOW TO BEST REPAIR
AN APPLICATION, WE SUMMARIZED
HERE JUST A FEW WHAT YOU
REVIEWERS ARE LOOKING FOR.
SO WE NEED TO DESCRIBE THE
SIGNIFICANCE AND IMPACT OF THE
RESEARCH FIELD FOR YOUR --
BASICALLY FOR YOUR RO-1 BECAUSE
THESE ARE 3, BETWEEN YEAR 3, ARE
FOCUSED ON OBTAINING PRELIMINARY
DATA TO SUPPORT A COMPETITIVE
RO-1 APPLICATION EMPLOY
REVIEWERS WILL WANT TO HEAR HOW
IMPACTFUL YOUR RO-1 WILL BE AND
HOW INNOVATIVE BUT FOR RO3, THE
SIGNIFICANCE CAN BE A LASTING
FACTOR.
YOU NEED TO PRESENT YOUR IDEAS
CLEARLY AND LOGICALLY AND DON'T
ASSUME THAT REVIEWERS UNDERSTAND
WHAT YOU WANT TO SAY.
IT'S ALWAYS GOOD TO ASK SOMEBODY
WHO'S NOT IN THE FIELD, TO MAKE
SURE THAT THEY CAN UNDERSTAND
WHAT YOU ARE SAYING.
WOULD BE GOOD TO OUTLINE THE
MECHANISTICS THAT DRIVE YOUR
REVIEW, ADDRESS ANY SPECIAL
REVIEW CRITERIA, IN THE CASE OF
THIS AWARD, THIS IS A TRIPLE
DOCUMENT AND A VISION FOR FUTURE
RO-1, YOU NEED TO PROPOSE
REALISTIC AIMS, AGAIN, THIS IS
JUST A 2 YEAR,A WARD, SO
SUBJECT, NUMBERS, BUDGET ALL
THIS SHOULD BE REALISTIC,
NONETHELESS, THE DESIGN SHOULD
COVER EXPERIMENTAL DETAILS, AND
COVER DETAILS ABOUT YOU IF YOU
ARE USING COMMON REVIEWS FOR
PROTOCOLS, DON'T SPEND MUCH TIME
ON THAT, IT'S JUST A 6 PAGE
APPLICATION, YOU CAN'T DEVOTE A
LOT OF TIME TO WHAT EVERYBODY
KNOWS.
NOTE THE LIMITATIONS OF THE
STUDY, POTENTIAL PIT FALLS AND
ALTERNATIVE APPROACHES, AND FOR
YOUR FIGURES AND TABLES INCLUDED
IN THE APPLICATION, PLEASE MAKE
SURE THAT THE FONT IS READABLE,
THE ERROR BARS ARE PRESENTED AND
THAT YOU SPECIFY THE SAMPLE SIZE
USED FOR THESE DATA.
THESE MAIDEN ANALYSIS OF THE
SUMMARY STATEMENTS FOR NONFUNDED
AND FUNDED APPLICATION AND
TRYING TO IDENTIFY 1 OF THE MOST
COMMON REVIEWERS COMMENTS
INCLUDING STRENGTH OF
VERIFICATION AND WEAKNESSES.
SO THE VERSIONS ARE HERE AND YOU
NEED TO PROVIDE STRONG
JUSTIFICATION FOR THE PROJECT
AND ITS SIGNATURES NOVEMBER CANC
EMPLOY WE NEED TO EMPHASIZE HOW
THE WORK IS NEW OR INNOVATIVE
AND AGAIN, WHILE YOU ARE RO3 MAY
BE LESS INNOVATIVE OR IMPACTFUL,
YOU SHOULD OUTLINE THE IMPACT
AND THE NOVELTY FOR YOUR FUTURE
RO-1.
YOU NEED TO INSURE THAT THE
PROPOSED RO3 PROJECT WILL
PRODUCE SUPPORTIVE DATA FOR AN
RO-1 APPLICATION.
YOU NEED TO BE VERY CLEAR ABOUT
THE EXPERIMENTAL PLANS INCLUDING
ANALYSIS, MEASURES, ET CETERA.
AND HOW THIS WILL PRODUCE THE
DESIRED DATA TO SUPPORT AN RO-1
APPLICATION.
MAKE SURE THAT THE AMOUNT OF
TIME IS APPROPRIATE FOR THE
PROPOSED PROJECT.
AGAIN, THIS IS A SHORT PROJECT,
3 YEARS.
SO YOU NEED TO ACCOUNT FOR DATA
COLLECTION, ESPECIALLY WITH
HUMAN SUBJECTS BUT ALSO SET THE
SITE FOR ANALYSIS.
SO THESE ARE THE MAIN POINTS FOR
YOUR DISTINGUISHED GOOD FROM NOT
SO GOOD APPLICATION.
WE ENCOURAGE YOU TO APPLY FOR
THIS MECHANISM.
WE THINK THAT THE BUDGET OF
200,000 IN DIRECT COSTS OVER 2
YEARS IS A GOOD SUPPORT
GONEERATE SUPPORT.
FOR THIS APPLICATION NO
PRELIMINARY DATA ARE REQUIRED,
YOU NEED TO JUSTIFY WHAT YOU'RE
PROPOSING BASED ON LITERATURE OR
MORE LITERATURE BUT YOU MAY NOT
SUBMIT ANY METADATA IN THIS
APPLICATION.
TO DEVELOP A GOOD RO-1
APPLICATION, YOU DO NEED DATA SO
HAD IS A STEP TOWARDS THE RO-1.
THE REVIEWERS FEEDBACK ON
PROPOSAL, SO CALLED SUMMARY
STATEMENT, CAN IMPROVE FUTURE
GRANT APPLICATIONS BECAUSE FOR
MANY APPLICANTS FOR THIS
PROGRAM, IT IS A FIRST NIH
APPLICATION.
AND ACROSS THE LAST 8 YEARS OF
FUNDING, THE RO3 WERE TWICE AS
LIKELY IN TOP 10 OF RO-1 THAN
HAD NONAWARDEES AND AGAIN THAT
GOES BACK TO THE FUTURE RO-1
APPLICATION NEEDS TO BE LIKE
THAT AND THIS IS THE WAY TO
GENERATE.
AS I MENTIONED BEFORE, IT'S RARE
THAT THE FIRST NIH APPLICATION
IS SUCCESSFUL.
SO HAVE YOU A CHANCE TO REVIEW
COMMENTS AND NOTES IN THE
SUMMARY STATEMENT AND USUALLY
CHANCES OF AWARD ON RESUBMISSION
ARE HIGHER THAN ON FIRST
SUBMISSION.
NONETHELESS, WE KNOW THAT LESS
THAN HALF OF APPLICANTS ELIGIBLE
FOR SUBMISSION, ARE SUBMITTING
APPLICATIONS.
WE DON'T GO UP, PLAN YOUR
SUBMISSION CAREFULLY.
BECAUSE ALL SUBMISSIONS WILL NOT
ALWAYS GET SUBSTANTIAL WORK YOU
SHOULDN'T ASSUME THIS WILL GO UP
AND YOU NEED TO PUT SERIOUS
EFFORTS INTO UNDERSTANDING AND
ADDRESSING REVIEWER CONCERNS.
NONDISCUSSED APPLICATIONS ON
FIRST SUBMISSIONS REQUIRE
SUBSTANTIAL WORK TO GET FUNDED
ON RESUBMISSION.
THAT MEANS THAT THEY'RE NOT
EXCITED ABOUT WHAT YOU NEED TO
DO AND THEN IT'S TIME TO STOP
AND THINK IS MY PROJECT WELL
DEFINED AT BASE MODEL.
AM I READY TO RESUBMIT OR SHOULD
I TAKE ANOTHER HALF YEAR AND
WORK ON IT TO SHAPE UP
HYPOTHESIS BETTER, MAKE SURE TO
COMMUNICATE WITH YOUR PROGRAM
OFFICERS TO COMMUNICATE ANY
PROBLEMS YOU EXPERIENCE.
SO IN GENERAL, TIPS, WE ALWAYS
ADVISE TO YOU COMMUNICATE WITH
NCMRR STAFF.
GENERAL QUESTIONS ABOUT
ELIGIBILITY, ABOUT MATCHING WITH
RESEARCH AREAS SHOULD BE
REFERRED TO.
YOU CAN CHECK ALL OUR PROGRAM
OFFICERS ON THE NCMRR WEBSITE
AND THERE IT WILL GIVE MORE
SPECIFICS ON THE HEELS OF
RESEARCH WHERE EACH OF OUR
PROGRAM OFFICES IS FOCUSED.
AS AN INTRODUCTION, YOU SHOULD
E-MAIL YOUR PAGE AND ASK FOR A
MEETING ON ZOOM, NOW DAYS IT'S
VERY EASY AND PROGRAM OFFICERS
WILL DISCUSS WITH YOU THE
POTENTIAL MECHANISMS, FUNDING
INITIATIVES AND THE REVIEW STUDY
SECTION ASSIGNMENT.
HERE I WANT TO NOTE, JUST NOTE,
THESE PARTICULAR NCMRR IS
REVIEWED WITH THE NICHD
INSTITUTE AND IT'S REVIEWED BY A
SPECIAL EMPHASIS PANEL.
SO THERE'S NO CONCERN FOR YOU
ABOUT WHERE IT WILL BE ASSIGNED
FOR REHAVE YOU, THERE IS JUST 1
STUDY SECTION WITHIN OUR
INSTITUTE THAT WILL REVIEW ALL
OF THESE APPLICATIONS.
AGAIN, IF YOU CAN GET THE
FEEDBACK FROM OTHER COLLEAGUES
AND MENTORS, DO IT.
BE EXCITED ABOUT YOUR WORK AND
CHECK ALL THE MATERIALS THAT NIH
POSTS FOR ATTENDANCE ON HOW TO
WRITE GRANT ANDS HOW TO PREPARE
GRANT APPLICATION.
SO, I WOULD LIKE TO THANK CHRIS
WHO IS OUR NEW SCIENTIFIC
PROGRAM ANALYST WITH NCMRR AND
HE DID A LOT OF LEG WORK IN
PUTTING THIS PRESENTATION
TOGETHER, SO THANK YOU, CHRIS.
AND NOW, I THINK IT'S A GOOD
TIME TO GO INTO QUESTIONS AND WE
WANT TO LEAVE MORE TIME TO
ANSWER YOUR QUESTIONS BECAUSE
ALL THE INFORMATION WHICH I
MENTIONED TO YOU IS WITH THE
FUNDING OPPORTUNITY ANNOUNCEMENT
AND YOU CAN FIND IT THERE.
>> THANK YOU, MARIA.
WE HAVE A FEW QUESTIONS.
DO YOU WANT TO GIVE YOUR VOICE A
BREAK AND YOU START ANSWERING
THE QUESTIONS.
>> YES.
>> THANK YOU FOR BEING A
TROOPER.
SO THE FIRST QUESTION IS, CAN
YOU BRIEFLY CLARIFY THE SCORE
FOR FACTOR 3 AND REMEMBER THAT'S
THE ENVIRONMENT AND THE
INVESTIGATOR AND WHAT ASPECTS
ARE CONSIDERED AND WHAT ARE NOT?
SO THE PURPOSE OF THE CHANGE
FACTOR 3 OR THOSE 2 REVIEW
CRITERIA, WAS MOTIVATED BY AN
OBSERVATION THAT SOME VERY WELL
ESTABLISHED INVESTIGATORS AND
SOME VERY WELL ESTABLISHED
INSTITUTIONS SEEM TO BE GETTING
ADVANTAGE IN REVIEW.
SO THEY MIGHT HAVE BEEN NOT AS
HELD TO THE SAME STANDARDS, SO
WHAT WE'RE TRYING TO DO IS SAY
WHETHER THE INVESTIGATORS SKILLS
ARE APPROPRIATE TO CONDUCT THE
WORK THAT IS PROPOSED.
SO IF AN APPLICATION DESCRIBES A
TECHNIQUE, THEN THERE SHOULD BE
EVIDENT THAT THAT PI KNOWS HOW
TO DO THAT TECHNIQUE, SO A
PREVIOUS PUBLICATION FOR
EXAMPLE, OR OTHER TYPES OF
TRAINING FOR THE ENVIRONMENT IT
MAY BE THINGS LIKE ACCESS TO
EQUIPMENT, ACCESS TO SPACE,
ACCESS TO PATIENT POPULATIONS.
SO ARE THE RESOURCES OF THE
ENVIRONMENT AVAILABLE TO CONDUCK
THE RESEARCH THAT WAS PROPOSED.
SO THOSE ARE GOING EITHER BE
ACCEPTABLE OR NOT ACCEPTABLE AND
THEN THE ASPECTS ARE MISSING OR
DESCRIBED BY THE REVIEWERS.
WILL THESE SLIDES BE AVAILABLE
ONLINE?
I'M GOING TO ASK THAT WE SEND
COPIES TO EVERYONE WHO IS
REGISTERED FOR THIS SO CAN YOU
GET THEM SOONER AND THEN WE WILL
WORK ON OUR END TO SEE WHETHER
WE CAN GET THEM POSTED BUT WE DO
INTEND THAT THIS WEBINAR IS
USEFUL BEYOND TODAY AND IS
AVAILABLE FOR FUTURE REFERENCE.
THERE'S A QUESTION ABOUT THE PAY
LINE FOR THIS MECHANISM.
NICHD DOESN'T USE PAY LINES FOR
THE RO3 MECHANISM.
SO WE HAVE A ZONE OF
CONSIDERATION THAT WE ARE ABLE
TO GIVEN ENOUGH FUNDS FOR THE
APPLICATIONS SO WE TRY TO FUND
AS MANY OF THESE AS WE CAN
BECAUSE WE THINK IT'S AN
IMPORTANT MECHANISM BUT WE DON'T
HAVE A SET PAY LINE, THAT'S WHAT
I CAN SHARE.
THOSE ARE THE 3 QUESTIONS THAT I
SEE IN THE Q&A BOX.
ARE THERE ANY OTHER?
ANY IN THE CHAT?
SOMETIMES THEY END UP THERE.
I WILL GIVE IT 1 MORE MINUTE.
WE HAVE A QUESTION: ARE CROSS
SECTIONAL STUDIES INVESTIGATING
A NEURAL MECHANISM IN PEOPLE
WITH STROKES SUITABLE FOR THIS
GRANT?
IT COULD BE.
YOU KNOW IF THERE ARE CLEAR
CONNECTIONS TO REHABILITATION
AND IS NOT JUST A BASIC SCIENCE
QUESTION THAT IS SEVERAL STEPS
AWAY FROM REHABILITATION, SO
THAT WOULD BE A GOOD EXAMPLE OF
A SET OF AIMS THAT YOU SHOULD
SEND TO MARIA, WHO MAY WANT TO
SHARE IT WITH ANOTHER PROGRAM
OFFICER SO WE CAN TALK ABOUT
WHETHER SHOULD WILL BE
APPLICABLE TO NCMRR'S MISSION.
OKAY, NOW WE'RE GETTING
QUESTIONS.
ALL RIGHT.
ARE THE NEW REVIEW FACTORS
APPLIED TO THE PROPOSALS THAT
ARE SUBMITTED START THANKSGIVING
FEBRUARY?
YES.
SO THE SIMPLIFIED REVIEW
FRAMEWORK GOES INTO EFFECT FOR
APPLICATIONS THAT COME IN AFTER
JANUARY 25th, 2025 EMPLOY SO
IF YOU ARE SUBMITTING, I THINK
THE NEXT DUE DATE'S IN FEBRUARY,
THEN YOU WOULD BE USING THE NEW
FRAMEWORK WHICH IS WHY WE HAD TO
REISSUE THE NOFO TO REFLECT THAT
NEW FRAMEWORK.
OKAY, QUESTION ABOUT THERE WAS
MENTION OF A SPECIAL EMPHASIS,
SRG, DOES THAT REVIEW GROUP ONLY
DO THE RO3s OR OTHER PROPOSALS
AS WELL?
SO WE'VE DONE IT A COUPLE
DIFFERENT WAYS.
THE CURRENT THINKING IS THAT IT
IS REVIEWED WITHIN OUR FIRST
STUDY SECTION, FUNCTION
INTEGRATION REHAB SCIENCES, SO
IT IS MOSTLY RO3s BUT THEY
ALSO COVER SOME K-AWARDS AS
WELL.
WE ALSO HAVE THE OPTION TO DO A
SEPARATE MEETING JUST OF THE
RO3s.
SO SOME OF THAT DEPENDS ON
WHETHER THERE IS WORK LOAD AND
TIMING AND THE NUMBER OF
APPLICATIONS BUT WE HAVE FAITH
IN OUR SRB, OUR SCIENTIFIC
REVIEW BRANCH AND THE QUALITY OF
THE REVIEW IS EXCELLENT.
AND JUST TO PUT A PIN ON THAT,
THE POINT MARIA WAS MAKING IS
THAT YOU DON'T HAVE TO FIND THE
STUDY SECTION, YOU DON'T HAVE TO
WORRY ABOUT MAKING
RECOMMENDATIONS.
WE'RE GOING TO SHOW THEM TO THE
RIGHT PLACE SO THAT'S SOMETHING
YOU DON'T HAVE TO BE CONCERNED
ABOUT.
SO CAN YOU TALK ABOUT THE
RESUBMISSION PROCESS?
SO IF YOU ARE STILL ELIGIBLE
WITHIN THAT TIME FRAME OF LESS
THAN 8 YEARS, YOU ARE WELCOME TO
SUBMIT AN AC1 APPLICATION THAT
IS WHAT WE CALL OUR
RESUBMISSIONS, WE RECOMMEND THAT
YOU TAKE THE TIME TO READ YOUR
SUMMARY STATEMENTS, TALK TO YOUR
COLLABORATORS, YOUR MENTORS
REACH OUT TO PROGRAM OFFICERS
AND GO OVER THOSE SUMMARY
STATEMENTS WITH YOU AND THEN
IT'S THE REGULAR PROCESS OF
RESUBMISSIONS, I BELIEVE IT'S
THE SAME DUE DATE AND CHRIS AND
MARIA CAN CHECK ME ON THAT FOR
THE SUBSEQUENT ROUNDS AND THERE
IS A 1 PAGE RESPONSE TO
REVIEWERS IN THAT.
>> YEAH, SO EACH APPLICATION
COMES ON 1 DATE, AND THEN THE
NEXT ISSUE COMES A MONTH LATER.
>> THANK YOU.
SO YOU HAVE A LITTLE EXTRA TIME
FOR RESUBMISSION .
ARE COLLABORATORS AND
CONSULTANTS ALLOWED?
YES.
PEOPLE WITH LIVED EXPERIENCE
SHOULD THEY SUBMIT BIOSKETCHES
IF THEY ARE KEY PERSONNEL EVEN
IF THEY ARE PATIENT ANDS NOT
SCIENTISTS?
SO THAT'S DPG TO BE DEPENDENT ON
THE WAY YOU FORMULATE THE PLAN.
SO WE'RE NOT BE DIRECTIVE IN
TELLING YOU HOW TO INCORPORATE
PEOPLE WITH LIVED EXPERIENCE,
CERTAINLY SOME APPLICATIONS THE
LIVED EXPERIENCE IS PART OF THE
RESEARCH TEAM AND THEN IT WOULD
BE REFLECTED IN A BIOSKETCH AND
OTHERS IT'S NOT.
SO YOU HAVE TO MAKE THAT CHOICE.
HOW MUCH CLINICAL TRAINING ARE
NEEDED IF THE PI IS FROM THE
AREA AND HAS SEVERAL YEARS OF
EXPERIENCE, DOES THAT COUNT?
SO THERE ISN'T A REQUIREMENT FOR
CLINICAL TRAINING SO WE EXPECT
THAT THE PI HAS EXPERIENCE AND
DEGREES IN RESEARCH OR IN
CLINICAL EXPERIENCE.
SO ENGINEERS, WE WELCOME
ENGINEERING APPLICATIONS.
WE GET MANY FROM Ph.D.s AND
ENGINEERING WHO WILL PROBABLY BE
WORKING WITH CLINICIANS BUT MAY
NOT HAVE THAT CLINICAL
EXPERIENCE THEMSELVES.
DOES THE GRANT REQUIRE APPLICANT
HAVING CITIZENSHIP OR PERMANENT
RESIDENT STATUS.
SO OUR GRANTS GENERALLY DO MOT
HAVE THAT REQUIREMENT SO YOU DO
NOT HAVE TO BE A U.S. CITIZEN TO
APPLY FOR AN RO3, THAT'S GOING
TO BE DIFFERENT IF YOU ARE
APPLYING FOR AN NRSA OR FOLLOW
OSHIP OR MOST OF THE CAREER
DEVELOP AM AWARDS.
BUT THIS RO3 DOES NOT HAVE THAT
REQUIREMENT.
CHRIS, MARIA, DID I GET ANYTHING
WRONG?
>> NO, EVERYTHING'S ALL RIGHT.
>> ALL RIGHT.
LOOKS LIKE WE HAVE 1 MORE
QUESTION.
TO SOMEONE WHO'S REFERENCING
TIGER OUR TRAINING AND
GRANTSMANSHIP REHAB RESEARCH,
ARE THERE WORKSHOPS OFFERED TO
SOLIDIFY THIS APPLICATION.
TIGER IS IT, TIGER IS OUR MAJOR
PROGRAM.
WE ALSO ATTEND AND PARTICIPATE
IN OTHER SOCIETIES AS
PROFESSIONAL ORGANIZATIONS WHO
HAVE EARLY CAREER WORKSHOPS
ASSOCIATED WITH OUR ANNUAL
MEETINGS SO WE TYPICALLY ATTEND
AMERICAN REHAB COMMERCE AND
MEDICINE, RAFFLE JACKPOT NIKIN
OUR DEPUTY DIRECTOR USUALLY
PARTICIPATES IN THAT EARLY
CAREER PROGRAM.
WE HAVE FUNDING, FEDERAL FUNDERS
PANELS AT PT MEETING, OT
MEETINGS, ENGINEERS,
BIOMECHANICS.
YOU KNOW WE TRAVEL WELL OR AS
MUCH AS WE CAN -- WHERE ARE MY
WORDS.
SO TIGER IS OUR MAIN GRANT
WRITING WORKSHOP, BUT WE DO
OFFER THOSE OTHER SMALLER
OPPORTUNITIES.
>> MAY I ADD HERE, THERESA, I
THINK TO SOLIDIFY APPLICATION, I
DON'T KNOW WHAT EXACTLY IS
IMPLIED HERE.
WE AS PROGRAM OFFICERS DO NOT
WORK ON THE APPLICATIONS, WE DO
FOCUS ON THE HELP YOU TO DESIGN
THEM, WE HELP YOU TO UNDERSTAND
WHAT REVIEWERS WERE CONCERNED
ABOUT, WE HELP YOU TO UNDERSTAND
IF THERE WAS ENTHUSIASM ABOUT
YOUR PROJECT BUT WE DON'T WORK
WITH INDIVIDUALS PIs TO CRAFT
THE APPLICATIONS.
DOES THIS ANSWER?
>> THAT'S AN EXCELLENT POINT.
THAT'S NOT THE PROGRAM OFFICER'S
ROLE.
OKAY.
ALL RIGHT.
I THINK THAT MIGHT BE IT FOR THE
QUESTIONS.
I JUST WANT TO SAY A HUGE THANKS
FIRST TO MARIA AND CHRIS FOR
PUTTING TOGETHER THE CONTENT OF
THIS PRESENTATION, THANKS TO ALL
THE PEOPLE BEHIND THE SCENES WHO
ARE MAKING SURE THIS IS RECORDED
AND THAT WE LOOK GOOD AND IT'S
SAVED AND ALL THOSE THINGS.
AND THEN OF COURSE, TO THE
ATTENDEES, WE HAVEN'T DONE A
WORKSHOP, A WEBINAR LIKE THIS SO
WE WEREN'T QUITE SURE HOW THE
RESPONSE WOULD BE BUT I AM VERY
PLEASED.
SO THANK YOU FOR COMING AND
SPENDING SOMETIME WITH US TODAY
ALL RIGHT.
AND WITH THAT, MARIA, DID YOU
WANT TO SAY ANYTHING ELSE?
>> NO, I WILL BE WAITING TO █SEE
THE APPLICATIONS, CONTACT ME
WITH ANY QUESTIONS ON
ELIGIBILITY, ON MATCHING THE
FOCUSES AND GOOD LUCK AND DON'T
GET DESPAIR IF YOUR FIRST
APPLICATION IS NOT FUNDED.
>> AND THAT IS A GREAT WAY TO
END IT.
SO THANK YOU EVERYBODY,