1 00:00:05,560 --> 00:00:10,400 I WANT TO NOW CALL TO ORDER THE 2 00:00:10,400 --> 00:00:14,120 OPEN SESSION OF THE 80TH MEETING 3 00:00:14,120 --> 00:00:16,520 OF THE NATIONAL ADVISORY COUNCIL 4 00:00:16,520 --> 00:00:17,000 FOR COMPLEMENTARY AND 5 00:00:17,000 --> 00:00:17,440 INTEGRATIVE HEALTH. 6 00:00:17,440 --> 00:00:18,120 I NOTE FOR THE RECORD THAT THIS 7 00:00:18,120 --> 00:00:19,000 MEETING IS BEING HELD VIRTUALLY 8 00:00:19,000 --> 00:00:21,520 FOR ALL COUNCILMEMBERS, MOST NIH 9 00:00:21,520 --> 00:00:24,600 STAFF, AND THE PUBLIC. 10 00:00:24,600 --> 00:00:26,680 MY NAME IS PARTAP KHALSA AND I 11 00:00:26,680 --> 00:00:28,200 SERVE AS THE EXECUTIVE SECRETARY 12 00:00:28,200 --> 00:00:29,640 FOR THIS COUNCIL AND AS PER 13 00:00:29,640 --> 00:00:31,400 FEDERAL REGULATIONS, I'M THE 14 00:00:31,400 --> 00:00:32,240 DESIGNATED FEDERAL OFFICIAL FOR 15 00:00:32,240 --> 00:00:35,320 THIS MEETING OF THIS NATIONAL 16 00:00:35,320 --> 00:00:36,080 ADVISORY COUNCIL. 17 00:00:36,080 --> 00:00:37,600 THIS COUNCIL MEETING IS CONVENED 18 00:00:37,600 --> 00:00:39,600 AS REQUIRED BY TITLE 42 OF THE 19 00:00:39,600 --> 00:00:43,000 U.S. CODE OF LAWS THAT GOVERN 20 00:00:43,000 --> 00:00:46,480 NIH IN GENERAL AND NCCIH 21 00:00:46,480 --> 00:00:47,280 SPECIFICALLY, AND IN ACCORDANCE 22 00:00:47,280 --> 00:00:49,000 WITH THE FEDERAL ADVISORY 23 00:00:49,000 --> 00:00:51,240 COMMITTEE ACT THAT IS CODIFIED 24 00:00:51,240 --> 00:00:53,080 IN TITLE 5 OF THE U.S. CODE OF 25 00:00:53,080 --> 00:00:53,520 LAWS. 26 00:00:53,520 --> 00:00:55,360 I NOTE THAT THE CLOSED SESSION 27 00:00:55,360 --> 00:00:58,560 OF THIS COUNCIL WAS HELD EARLIER 28 00:00:58,560 --> 00:01:00,320 THIS MORNING AND WAS CLOSED TO 29 00:01:00,320 --> 00:01:01,080 THE PUBLIC IN ACCORDANCE WITH 30 00:01:01,080 --> 00:01:02,720 THE GOVERNMENT IN THE SUNSHINE 31 00:01:02,720 --> 00:01:04,800 ACT, AND AS CODIFIED IN TITLE 32 00:01:04,800 --> 00:01:08,200 5 OF U.S. CODE, DEALING WITH 33 00:01:08,200 --> 00:01:09,000 ADMINISTRATIVE PROCEDURES FOR 34 00:01:09,000 --> 00:01:09,840 FEDERAL AGENCIES. 35 00:01:09,840 --> 00:01:12,920 WE WILL ENDEAVOR TO FINISH THE 36 00:01:12,920 --> 00:01:15,080 OPEN SESSION THIS AFTERNOON BY 37 00:01:15,080 --> 00:01:17,640 4:30 P.M. EASTERN TIME. 38 00:01:17,640 --> 00:01:18,480 THE OPEN SESSION OF COUNCIL IS 39 00:01:18,480 --> 00:01:20,480 OPEN TO THE GENERAL PUBLIC TO 40 00:01:20,480 --> 00:01:23,360 ATTEND BY A LIVE NIH VIDEOCAST 41 00:01:23,360 --> 00:01:26,960 AND THIS CAN AND MAY BE VIEWED 42 00:01:26,960 --> 00:01:27,920 BY INDIVIDUALS ACROSS THE 43 00:01:27,920 --> 00:01:29,040 COUNTRY AND INDEED AROUND THE 44 00:01:29,040 --> 00:01:31,160 WORLD. 45 00:01:31,160 --> 00:01:35,040 THE OPEN SESSION WILL INCLUDE 46 00:01:35,040 --> 00:01:38,200 REMARKS AND A REVIEW -- EXCUSE 47 00:01:38,200 --> 00:01:41,760 ME, THESE REMARKS, AND THEY WILL 48 00:01:41,760 --> 00:01:44,160 BE FOLLOWED BY THE NCCIH 49 00:01:44,160 --> 00:01:45,240 DIRECTOR'S REPORT TO COUNCIL. 50 00:01:45,240 --> 00:01:46,800 WE WILL THEN BREAK FOR LUNCH, 51 00:01:46,800 --> 00:01:48,440 AND FOLLOWING LUNCH, WE WILL 52 00:01:48,440 --> 00:01:50,320 RECONVENE AT 1:20 P.M. EASTERN 53 00:01:50,320 --> 00:01:52,920 TIME AND THERE WILL BE A 54 00:01:52,920 --> 00:02:03,440 PRESENTATION BY DR. DSOUZA ON 55 00:02:03,720 --> 00:02:05,080 RESEARCH PRIORITIES FOR 56 00:02:05,080 --> 00:02:05,840 TEMPOROMANDIBULAR DISORDERS AND 57 00:02:05,840 --> 00:02:07,800 SHARED INTERESTS WITH NCCIH. 58 00:02:07,800 --> 00:02:09,440 FOLLOWING THAT, THERE WILL BE A 59 00:02:09,440 --> 00:02:11,400 MINI SYMPOSIUM ON CLINICAL 60 00:02:11,400 --> 00:02:12,320 TRIALS TO ADDRESS STRESS IN 61 00:02:12,320 --> 00:02:13,600 DIFFERENT CONTEXTS AND WHAT 62 00:02:13,600 --> 00:02:17,120 MAKES TRIALS IMPACTFUL. 63 00:02:17,120 --> 00:02:18,320 FINALLY, WE WILL HAVE THREE 64 00:02:18,320 --> 00:02:19,840 CONCEPT CLEARANCES WHICH WILL BE 65 00:02:19,840 --> 00:02:21,480 ON, FIRST, VALIDATION STUDIES OF 66 00:02:21,480 --> 00:02:24,120 ANALYTICAL METHODS FOR DIETARY 67 00:02:24,120 --> 00:02:25,760 SUPPLEMENT CONSTITUENTS. 68 00:02:25,760 --> 00:02:27,000 THE SECOND CONCEPT WILL BE ON 69 00:02:27,000 --> 00:02:30,600 RESEARCH NETWORKS TO PROMOTE 70 00:02:30,600 --> 00:02:31,920 INNOVATIVE MECHANISTIC AND 71 00:02:31,920 --> 00:02:34,560 TRANSLATIONAL STUDIES OF SICKLE 72 00:02:34,560 --> 00:02:35,840 CELL DISEASE PAIN, AND THE THIRD 73 00:02:35,840 --> 00:02:38,160 WILL BE ON BUILDING 74 00:02:38,160 --> 00:02:39,360 CROSS-CUTTING RESEARCH NETWORKS 75 00:02:39,360 --> 00:02:41,360 TO PROMOTE MULTIDISCIPLINARY 76 00:02:41,360 --> 00:02:42,840 MECHANISTIC STUDIES OF MUSIC AND 77 00:02:42,840 --> 00:02:45,720 HEALTH. 78 00:02:45,720 --> 00:02:46,280 COUNCILMEMBERS HAVE ALREADY 79 00:02:46,280 --> 00:02:49,000 RECEIVED A COPY OF THE 80 00:02:49,000 --> 00:02:51,840 JANUARY 2022 MEETING MINUTES IN 81 00:02:51,840 --> 00:02:53,160 THE ELECTRONIC COUNCIL BOOK, AND 82 00:02:53,160 --> 00:02:56,640 AT THIS TIME, I WOULD LIKE TO 83 00:02:56,640 --> 00:02:59,680 FINALIZE THE MINUTES, 84 00:02:59,680 --> 00:03:00,680 SPECIFICALLY ARE THERE ANY 85 00:03:00,680 --> 00:03:02,240 CORRECTIONS TO THE COUNCIL 86 00:03:02,240 --> 00:03:04,320 MEETING MINUTES? 87 00:03:04,320 --> 00:03:06,040 I'M GOING TO ASK COUNCILMEMBERS 88 00:03:06,040 --> 00:03:07,840 IF THEY HAVE ANY COMMENTS TO GO 89 00:03:07,840 --> 00:03:09,040 AHEAD AND RAISE THEIR DIGITAL 90 00:03:09,040 --> 00:03:10,880 HANDS ON THE ZOOM OR WAVE AT ME 91 00:03:10,880 --> 00:03:18,360 VIA THEIR VIDEO FEED. 92 00:03:18,360 --> 00:03:19,680 SEEING NONE, I WILL ASK FOR A 93 00:03:19,680 --> 00:03:20,480 MOTION FOR APPROVAL OF THE 94 00:03:20,480 --> 00:03:21,000 MEETING MINUTES. 95 00:03:21,000 --> 00:03:25,240 I NEED TO HEAR THAT AUDITOR ILY 96 00:03:25,240 --> 00:03:26,000 BY ONE COUNCILMEMBER. 97 00:03:26,000 --> 00:03:26,240 >> I MOVE. 98 00:03:26,240 --> 00:03:27,240 >> AND A SECOND? 99 00:03:27,240 --> 00:03:27,680 >> SECOND. 100 00:03:27,680 --> 00:03:28,880 >> AND IS THERE ANY FURTHER 101 00:03:28,880 --> 00:03:33,080 DISCUSSION BEFORE WE VOTE IN AND 102 00:03:33,080 --> 00:03:35,240 SO WHAT I'D LIKE TO HAVE IS 103 00:03:35,240 --> 00:03:37,200 THAT, AGAIN, THERE WILL BE A 104 00:03:37,200 --> 00:03:40,800 POLL QUESTION APPEARING ON YOUR 105 00:03:40,800 --> 00:03:41,400 SCREEN. 106 00:03:41,400 --> 00:03:44,960 YOU'RE VOTING TO APPROVE THE 107 00:03:44,960 --> 00:03:46,960 JANUARY 2022 COUNCIL MEETINGS, A 108 00:03:46,960 --> 00:03:48,360 VOTE OF YES MEANS YOU'RE 109 00:03:48,360 --> 00:03:49,360 APPROVING, A VOTE OF NO MEANS 110 00:03:49,360 --> 00:03:59,880 YOU'RE NOT, AND YOU CAN ABSTAIN. 111 00:04:03,240 --> 00:04:04,400 I SEE THE THING BUT I DON'T SEE 112 00:04:04,400 --> 00:04:10,640 THE NUMBER OF COUNCIL VOTES. 113 00:04:10,640 --> 00:04:12,360 CAN YOU TELL ME IF WE'VE GOT ALL 114 00:04:12,360 --> 00:04:13,480 THE VOTES? 115 00:04:13,480 --> 00:04:13,720 >> YES. 116 00:04:13,720 --> 00:04:14,720 >> SO IT'S UNANIMOUS? 117 00:04:14,720 --> 00:04:15,040 ALL RIGHT. 118 00:04:15,040 --> 00:04:16,520 SO THE COUNCIL MINUTES ARE 119 00:04:16,520 --> 00:04:17,280 APPROVED UNANIMOUSLY. 120 00:04:17,280 --> 00:04:21,360 THANK YOU. 121 00:04:21,360 --> 00:04:22,320 THERE WE GO. 122 00:04:22,320 --> 00:04:24,400 LATE TO THE PARTY. 123 00:04:24,400 --> 00:04:27,480 FUTURE COUNCIL MEETING DATES ARE 124 00:04:27,480 --> 00:04:29,800 NOTED ON THE AGENDA WHICH 125 00:04:29,800 --> 00:04:30,360 COUNCILMEMBERS HAVE ALREADY 126 00:04:30,360 --> 00:04:30,800 RECEIVED. 127 00:04:30,800 --> 00:04:35,360 OUR NEXT MEETING WILL BE ON 128 00:04:35,360 --> 00:04:37,320 AUGUST 12TH, 2022, AS CLOSED 129 00:04:37,320 --> 00:04:38,520 SESSION ONLY. 130 00:04:38,520 --> 00:04:39,640 AND THAT WILL THEN BE FOLLOWED 131 00:04:39,640 --> 00:04:41,840 BY A REGULAR MEETING OF COUNCIL 132 00:04:41,840 --> 00:04:43,720 MEETING, BOTH CLOSED AND OPEN 133 00:04:43,720 --> 00:04:46,000 SESSIONS, ON FRIDAY, 134 00:04:46,000 --> 00:04:47,720 SEPTEMBER 9TH OF THIS YEAR. 135 00:04:47,720 --> 00:04:48,840 IF THERE'S ANY CHANGE TO THESE 136 00:04:48,840 --> 00:04:52,760 DATES FOR ANY REASON, IT WILL BE 137 00:04:52,760 --> 00:04:54,400 ANNOUNCED IN ADVANCE. 138 00:04:54,400 --> 00:04:55,520 PLEASE BE SURE TO LET US KNOW AS 139 00:04:55,520 --> 00:04:56,480 SOON AS YOU KNOW IF YOU WILL NOT 140 00:04:56,480 --> 00:04:58,360 BE ABLE TO ATTEND ANY GIVEN 141 00:04:58,360 --> 00:05:00,880 MEETING. 142 00:05:00,880 --> 00:05:02,200 THE LAST AGENDA ITEM FOR THE 143 00:05:02,200 --> 00:05:04,080 OPEN SESSION LATER THIS 144 00:05:04,080 --> 00:05:06,600 AFTERNOON IS A PUBLIC COMMENT 145 00:05:06,600 --> 00:05:06,840 SESSION. 146 00:05:06,840 --> 00:05:07,880 BECAUSE THIS COUNCIL MEETING IS 147 00:05:07,880 --> 00:05:10,440 BEING HELD VIRTUALLY RATHER THAN 148 00:05:10,440 --> 00:05:12,640 IN PERSON FOR ALMOST EVERYBODY, 149 00:05:12,640 --> 00:05:14,040 THEN IT'S NOT POSSIBLE FOR 150 00:05:14,040 --> 00:05:15,800 MEMBERS OF THE PUBLIC TO MAKE 151 00:05:15,800 --> 00:05:16,480 IN-PERSON COMMENTS. 152 00:05:16,480 --> 00:05:18,200 AS SUCH, ANY MEMBER OF THE 153 00:05:18,200 --> 00:05:20,080 PUBLIC WHO WISHES TO MAKE A 154 00:05:20,080 --> 00:05:21,720 PUBLIC COMMENT MAY DO SO BY 155 00:05:21,720 --> 00:05:26,160 SENDING ME YOUR WRITTEN COMMENTS 156 00:05:26,160 --> 00:05:28,800 WITHIN 15 DAYS OF THE CON CONCLN 157 00:05:28,800 --> 00:05:29,480 OF THIS MEETING. 158 00:05:29,480 --> 00:05:32,840 THIS CAN BE DONE EITHER BY EMAIL 159 00:05:32,840 --> 00:05:34,600 OR HARD COPY LETTER. 160 00:05:34,600 --> 00:05:35,840 YOUR WRITTEN COMMENTS SHOULD BE 161 00:05:35,840 --> 00:05:38,240 LESS THAN 700 WORDS IN LENGTH, 162 00:05:38,240 --> 00:05:40,840 WHICH IS CONSISTENT WITH A 163 00:05:40,840 --> 00:05:41,840 FIVE-MINUTE ORAL PRESENTATION. 164 00:05:41,840 --> 00:05:44,240 YOUR WRITTEN COMMENT WILL BE 165 00:05:44,240 --> 00:05:46,280 ADDED TO THE MINUTES -- OR 166 00:05:46,280 --> 00:05:47,720 SHARED TO COUNCIL VIA THE 167 00:05:47,720 --> 00:05:51,680 ELECTRONIC COUNCIL BOOK. 168 00:05:51,680 --> 00:05:57,240 DR. LANGEVIN, PLEASE PROCEED. 169 00:05:57,240 --> 00:05:59,320 >> THANK YOU SO MUCH, 170 00:05:59,320 --> 00:05:59,640 DR. KHALSA. 171 00:05:59,640 --> 00:06:03,040 IT'S NOW MY DISTINCT PLEASURE TO 172 00:06:03,040 --> 00:06:06,440 SHARE MY DIRECTOR'S REPORT TO 173 00:06:06,440 --> 00:06:16,600 COUNCIL. 174 00:06:20,280 --> 00:06:20,760 ALL RIGHT. 175 00:06:20,760 --> 00:06:22,520 WE'RE GOING TO START WITH SOME 176 00:06:22,520 --> 00:06:26,520 GENERAL NIH NEWS. 177 00:06:26,520 --> 00:06:30,040 WE HAVE HAD RECENTLY THE 178 00:06:30,040 --> 00:06:32,760 ANNOUNCED IMPENDING DEPARTURE OF 179 00:06:32,760 --> 00:06:35,480 DR. NED SHARPLESS, WHO HAS 180 00:06:35,480 --> 00:06:37,520 STEPPED DOWN AS THE DIRECTOR OF 181 00:06:37,520 --> 00:06:40,080 THE NATIONAL CANCER INSTITUTE. 182 00:06:40,080 --> 00:06:41,920 DR. SHARPLESS HAS BEEN DIRECTOR 183 00:06:41,920 --> 00:06:44,840 OF THE NCI SINCE 2017. 184 00:06:44,840 --> 00:06:51,760 AND HE ALSO, DURING THAT TIME, 185 00:06:51,760 --> 00:06:53,280 WAS ASKED TO FILL IN AND ACT AS 186 00:06:53,280 --> 00:06:55,960 THE ACTING COMMISSIONER FOR FOOD 187 00:06:55,960 --> 00:06:57,680 AND DRUG AT THE U.S. FOOD AND 188 00:06:57,680 --> 00:06:59,640 DRUG ADMINISTRATION, FDA, FOR 189 00:06:59,640 --> 00:07:00,720 SEVEN MONTHS, IN 2019. 190 00:07:00,720 --> 00:07:04,360 AND THEN HE CAME BACK TO NCI, 191 00:07:04,360 --> 00:07:09,280 AND NOW, AFTER HIS DEPARTURE, 192 00:07:09,280 --> 00:07:12,440 PRINCIPAL DEPUTY DIRECTOR 193 00:07:12,440 --> 00:07:15,600 DOUGLAS LOWY IS SERVING AS NCI'S 194 00:07:15,600 --> 00:07:18,400 ACTING DIRECTOR. 195 00:07:18,400 --> 00:07:20,040 ANOTHER -- WE ALSO WANT TO 196 00:07:20,040 --> 00:07:30,080 WELCOME DR. JULIE GERBEDING, 197 00:07:30,080 --> 00:07:31,680 PREVIOUSLY SERVED AS DIRECTOR OF 198 00:07:31,680 --> 00:07:35,440 THE CDC AS WELL AS THE CHIEF 199 00:07:35,440 --> 00:07:38,160 PATIENT OFFICER AND EXECUTIVE 200 00:07:38,160 --> 00:07:39,280 VICE PRESIDENT OF MERCK. 201 00:07:39,280 --> 00:07:41,680 SO WE ARE VERY PLEASED THAT 202 00:07:41,680 --> 00:07:43,560 SHE'S NOW GOING TO BE LEADING 203 00:07:43,560 --> 00:07:48,040 FNIH. 204 00:07:48,040 --> 00:07:51,560 NOW FOR SOME STAFF UPDATES AT 205 00:07:51,560 --> 00:07:52,320 NCCIH. 206 00:07:52,320 --> 00:07:54,280 WE WOULD LIKE TO ALL PLEASE JOIN 207 00:07:54,280 --> 00:07:56,480 ME IN WELCOMING SEVERAL NULL 208 00:07:56,480 --> 00:07:59,680 PROGRAM NEW 209 00:07:59,680 --> 00:08:01,160 PROGRAM OFFICERS. 210 00:08:01,160 --> 00:08:02,960 A NEW PROGRAM DIRECTOR IN THE 211 00:08:02,960 --> 00:08:05,920 CLINICAL RESEARCH BRANCH AT 212 00:08:05,920 --> 00:08:08,520 NCCIH, DR. CHIDEYA, WHERE HER 213 00:08:08,520 --> 00:08:10,320 PORTFOLIO INCLUDES HEALTH 214 00:08:10,320 --> 00:08:11,960 DISPARITIES, POPULATION HEALTH 215 00:08:11,960 --> 00:08:16,440 AND DISEASE MANAGEMENT, MHEALTH 216 00:08:16,440 --> 00:08:17,200 INTERVENTIONS AND PRODUCTS 217 00:08:17,200 --> 00:08:17,600 RESEARCH. 218 00:08:17,600 --> 00:08:23,640 SHE IS ESPECIALLY INTERESTED IN 219 00:08:23,640 --> 00:08:24,760 FINDING -- EXPLORING THE UTILITY 220 00:08:24,760 --> 00:08:26,480 OF NATURAL PRODUCTS FOR MENTAL 221 00:08:26,480 --> 00:08:27,880 HEALTH AND ISSUES RELATED TO 222 00:08:27,880 --> 00:08:29,120 PALLIATIVE CARE. 223 00:08:29,120 --> 00:08:33,720 PRIOR TO JOINING NCCIH, 224 00:08:33,720 --> 00:08:34,360 DR. CHIDEYA WORKED FOR APPLE, 225 00:08:34,360 --> 00:08:35,920 WHERE SHE STRENGTHENED 226 00:08:35,920 --> 00:08:37,040 POPULATION HEALTH INITIATIVES 227 00:08:37,040 --> 00:08:40,880 AND SPEARHEADED A MULTI-PLATFORM 228 00:08:40,880 --> 00:08:43,360 INTERVENTION FOR GENERALIZED 229 00:08:43,360 --> 00:08:44,360 ANXIETY DISORDER. 230 00:08:44,360 --> 00:08:47,640 SHE'S A TRAINED MEDICAL 231 00:08:47,640 --> 00:08:49,280 EPIDEMIOLOGIST, AND WE ARE VERY, 232 00:08:49,280 --> 00:08:52,240 VERY PLEASED TO HAVE DR. CHIDEYA 233 00:08:52,240 --> 00:08:57,200 JOIN US AT NCCIH. 234 00:08:57,200 --> 00:08:59,280 NEXT IS A PROGRAM DIRECTOR IN 235 00:08:59,280 --> 00:09:01,320 THE CLINICAL RESEARCH BRANCH IN 236 00:09:01,320 --> 00:09:06,200 THE DIVISION OF EXTRAMURAL 237 00:09:06,200 --> 00:09:08,680 RESEARCH, OVERSEEING A PORTFOLIO 238 00:09:08,680 --> 00:09:09,720 OF CLINICAL RESEARCH INCLUDING 239 00:09:09,720 --> 00:09:11,440 HEALTH DISPARITIES, PEDIATRIC 240 00:09:11,440 --> 00:09:15,520 RESEARCH ON MENTAL AND EMOTIONAL 241 00:09:15,520 --> 00:09:16,600 WELL-BEING, MATERNAL MORBIDITY 242 00:09:16,600 --> 00:09:18,840 AND MORTALITY AND PRAGMATIC 243 00:09:18,840 --> 00:09:20,360 CLINICAL TRIALS. 244 00:09:20,360 --> 00:09:21,640 ADDITIONALLY SHE CONTRIBUTES TO 245 00:09:21,640 --> 00:09:25,600 THE MENTAL EMOTIONAL AND 246 00:09:25,600 --> 00:09:27,200 BEHAVIORAL OR MEB FLISHTIVES, AS 247 00:09:27,200 --> 00:09:30,320 WELL AS THE PRAGMATIC TRIALS 248 00:09:30,320 --> 00:09:30,640 COLLABORATORY. 249 00:09:30,640 --> 00:09:34,800 BEFORE JOINING NCCIH, 250 00:09:34,800 --> 00:09:36,480 DR. JEAN-FRANCOIS SERVED AS 251 00:09:36,480 --> 00:09:37,440 ADMINISTRATOR AT THE NATIONAL 252 00:09:37,440 --> 00:09:38,880 INSTITUTE OF MINORITY HEALTH AND 253 00:09:38,880 --> 00:09:39,960 HEALTH DISPARITIES, WHERE SHE 254 00:09:39,960 --> 00:09:41,600 CO-LED THE DATA COORDINATING 255 00:09:41,600 --> 00:09:52,160 CENTER FOR THE RADX INITIATIVE. 256 00:09:55,160 --> 00:09:57,280 WELCOME, DR. JEAN-FRANCOIS. 257 00:09:57,280 --> 00:10:04,640 NEXT I WOULD LIKE TO WELCOME DRM 258 00:10:04,640 --> 00:10:05,840 DIRECTOR IN THE BASIC AND 259 00:10:05,840 --> 00:10:10,200 MECHANISTIC RESEARCH BRANCH. 260 00:10:10,200 --> 00:10:11,080 DR. TUTTLE CURRENTLY LEADS 261 00:10:11,080 --> 00:10:12,400 SEVERAL TRANS-NIH INITIATIVES, 262 00:10:12,400 --> 00:10:15,320 INCLUDING THE HEAL MYOFASCIAL 263 00:10:15,320 --> 00:10:16,440 PAIN BIOMARKERS PROGRAM AND THE 264 00:10:16,440 --> 00:10:17,880 FORCE BASED MANIPULATION 265 00:10:17,880 --> 00:10:20,280 RESEARCH NETWORKS PROGRAM. 266 00:10:20,280 --> 00:10:23,120 HIS ADDITIONAL PROGRAMMATIC 267 00:10:23,120 --> 00:10:24,000 EFFORTS WILL INCLUDE DEVELOPING 268 00:10:24,000 --> 00:10:25,760 RESEARCH INITIATIVES INVOLVING 269 00:10:25,760 --> 00:10:28,040 MULTIORGAN SYSTEMS AND 270 00:10:28,040 --> 00:10:28,960 MULTICOMPONENT INTERVENTIONS 271 00:10:28,960 --> 00:10:30,480 CENTERING AROUND THE 272 00:10:30,480 --> 00:10:31,640 MUSCULOSKELETAL SYSTEM. 273 00:10:31,640 --> 00:10:34,600 PRIOR TO JOINING NCCIH, 274 00:10:34,600 --> 00:10:36,200 DR. TUTTLE SERVED AS ACTING 275 00:10:36,200 --> 00:10:37,800 CHIEF OF STAFF FOR THE NATIONAL 276 00:10:37,800 --> 00:10:38,560 INSTITUTES OF NEUROLOGICAL 277 00:10:38,560 --> 00:10:40,960 DISORDERS AND STROKE, OR NINDS. 278 00:10:40,960 --> 00:10:43,160 HE ALSO SERVED AS A LEAD PROGRAM 279 00:10:43,160 --> 00:10:47,680 ANALYST FOR THE HEAL ANALYST 280 00:10:47,680 --> 00:10:49,680 THINK TANK. 281 00:10:49,680 --> 00:10:52,080 SO WELCOME TO ALL OF THESE 282 00:10:52,080 --> 00:11:01,160 WONDERFUL NEW PROGRAM STAFF. 283 00:11:01,160 --> 00:11:10,560 I AM ALSO HAPPY TO WELCOME 284 00:11:10,560 --> 00:11:11,840 DR. BACKONJA AS ACTING CLINICAL 285 00:11:11,840 --> 00:11:12,120 DIRECTOR. 286 00:11:12,120 --> 00:11:14,160 OF COURSE WE ALSO WANT TO THANK 287 00:11:14,160 --> 00:11:15,880 DR. MARILYN POWELL, WHO HAS BEEN 288 00:11:15,880 --> 00:11:18,040 SERVING AS THE ACTING CLINICAL 289 00:11:18,040 --> 00:11:23,760 DIRECTOR AT NCCIH SINCE 2020. 290 00:11:23,760 --> 00:11:28,360 FLAD TO HER WORK AT NCCIH, 291 00:11:28,360 --> 00:11:30,440 DR. PAO HAS ALSO BEEN SERVING AT 292 00:11:30,440 --> 00:11:32,120 THE NATIONAL INSTITUTES OF 293 00:11:32,120 --> 00:11:33,200 MENTAL HEALTH. 294 00:11:33,200 --> 00:11:33,960 INTRAMURAL RESEARCH PROGRAM. 295 00:11:33,960 --> 00:11:36,040 WE TRULY APPRECIATE VERY, VERY 296 00:11:36,040 --> 00:11:37,600 GRATEFUL FOR DR. PAO FOR 297 00:11:37,600 --> 00:11:39,200 EVERYTHING SHE HAS DONE FOR US 298 00:11:39,200 --> 00:11:40,200 AT NCCIH, AND WE REALLY LOOK 299 00:11:40,200 --> 00:11:41,960 FORWARD TO CONTINUING TO WORK 300 00:11:41,960 --> 00:11:45,880 WITH HER IN THE FUTURE. 301 00:11:45,880 --> 00:11:49,880 WE ALSO NOW HAVE A NUMBER OF NEW 302 00:11:49,880 --> 00:11:51,840 ARRIVALS AND DEPARTURES. 303 00:11:51,840 --> 00:11:58,520 ONE DEPARTURE, RETIRING FROM THE 304 00:11:58,520 --> 00:11:59,920 OFFICE OF POLICY PLANNING AND 305 00:11:59,920 --> 00:12:01,000 EVALUATION, SHE'S BEEN AT NCCIH 306 00:12:01,000 --> 00:12:05,200 FOR MANY YEARS, AND OUR NEW 307 00:12:05,200 --> 00:12:06,280 ARRIVALS IN THE OFFICE OF 308 00:12:06,280 --> 00:12:08,120 COMMUNICATIONS AND EXTRAMURAL 309 00:12:08,120 --> 00:12:09,240 RESEARCH, EXTRAMURAL ACTIVITIES 310 00:12:09,240 --> 00:12:14,600 AND INTRAMURAL RESEARCH AS WELL. 311 00:12:14,600 --> 00:12:16,360 NOW OUR BUDGET. 312 00:12:16,360 --> 00:12:17,360 SO JUST TO KIND OF GUIDE YOU 313 00:12:17,360 --> 00:12:18,640 THROUGH A LITTLE BIT THIS 314 00:12:18,640 --> 00:12:20,120 MECHANISM TABLE THAT WE SHOWED 315 00:12:20,120 --> 00:12:22,840 TO SHOW TO 316 00:12:22,840 --> 00:12:24,080 YOU EVERY TIME, OBVIOUSLY THE 317 00:12:24,080 --> 00:12:25,120 NUMBERS THAT ARE HERE ARE ALWAYS 318 00:12:25,120 --> 00:12:29,840 A LITTLE BIT LAGGING, BUT WHAT I 319 00:12:29,840 --> 00:12:33,120 DO WANT TO POINT OUT IS THAT IN 320 00:12:33,120 --> 00:12:36,840 FY 22, WE RECEIVED A 3.4% 321 00:12:36,840 --> 00:12:40,640 INCREASE, SO OUR BUDGET WEN FROM 322 00:12:40,640 --> 00:12:42,040 $153,000,616 YOU SEE AT THE 323 00:12:42,040 --> 00:12:48,040 BOTTOM TO $159,000,365. 324 00:12:48,040 --> 00:12:53,040 NOW, THIS ALSO KIND OF RESULTED 325 00:12:53,040 --> 00:12:54,600 IN A GRADUAL SORT OF INCREASE IN 326 00:12:54,600 --> 00:12:56,880 THE AMOUNT OF MONEY THAT WE HAVE 327 00:12:56,880 --> 00:12:58,960 BEEN ABLE TO PUT TOWARDS 328 00:12:58,960 --> 00:13:01,840 RESEARCH PROJECTS. 329 00:13:01,840 --> 00:13:04,120 AT PREVIOUS COUNCILS WE HAD 330 00:13:04,120 --> 00:13:08,120 TALKED ABOUT THE POSSIBILITY IN 331 00:13:08,120 --> 00:13:09,160 THE FY 22 PRESIDENT'S BUDGET, 332 00:13:09,160 --> 00:13:13,120 THERE HAD BEEN A SUBSTANTIAL 333 00:13:13,120 --> 00:13:14,120 INCREASE TO NCCIH SPECIFICALLY 334 00:13:14,120 --> 00:13:16,960 FOR PAIN RESEARCH. 335 00:13:16,960 --> 00:13:18,600 THIS DID NOT COME TO FRUIT. 336 00:13:18,600 --> 00:13:20,880 WE DID NOT GET THIS INCREASE. 337 00:13:20,880 --> 00:13:23,840 HOWEVER, AS YOU CAN SEE IN THE 338 00:13:23,840 --> 00:13:28,320 FY 23 BUDGET, THE INCREASE IS, 339 00:13:28,320 --> 00:13:29,720 AGAIN, BACK IN THE PRESIDENT'S 340 00:13:29,720 --> 00:13:30,160 BUDGET. 341 00:13:30,160 --> 00:13:31,840 SO YOU CAN SEE THAT THE TOTAL AT 342 00:13:31,840 --> 00:13:35,080 THE BOTTOM WOULD GO UP TO 343 00:13:35,080 --> 00:13:39,080 $183 MILLION. 344 00:13:39,080 --> 00:13:40,800 $183,000,368. 345 00:13:40,800 --> 00:13:41,720 HOWEVER, AS WAS DEMONSTRATED 346 00:13:41,720 --> 00:13:43,960 LAST YEAR, THE PRESIDENT'S 347 00:13:43,960 --> 00:13:45,400 BUDGET DOES NOT OBVIOUSLY 348 00:13:45,400 --> 00:13:50,600 GUARANTEE ANYTHING. 349 00:13:50,600 --> 00:13:54,040 BUT THIS IS WHERE WE STAND RIGHT 350 00:13:54,040 --> 00:13:54,200 NOW. 351 00:13:54,200 --> 00:13:59,840 WE HAVE -- SO THERE IS A 352 00:13:59,840 --> 00:14:00,720 PROPOSED $183 MILLION, SO AN 353 00:14:00,720 --> 00:14:03,160 INCREASE OF $29 MILLION, 354 00:14:03,160 --> 00:14:03,840 SPECIFICALLY $26 MILLION OF THIS 355 00:14:03,840 --> 00:14:05,880 WOULD BE ALLOCATED TO EXPANDING 356 00:14:05,880 --> 00:14:08,400 NCCIH'S RESEARCH INTO PAIN AND 357 00:14:08,400 --> 00:14:09,280 PAIN MANAGEMENT. 358 00:14:09,280 --> 00:14:12,360 THIS REALLY IS, YOU KNOW, A 359 00:14:12,360 --> 00:14:17,400 REFLECTION OF THE VERY IMPORTANT 360 00:14:17,400 --> 00:14:18,360 RESEARCH, LEADERSHIP AND 361 00:14:18,360 --> 00:14:19,680 CONTRIBUTION THAT NCCIH HAS MADE 362 00:14:19,680 --> 00:14:22,120 IN THE AREA OF PAIN IN THE PAST, 363 00:14:22,120 --> 00:14:25,720 SO WE'LL JUST SEE WHAT HAPPENS 364 00:14:25,720 --> 00:14:29,320 WITH THIS. 365 00:14:29,320 --> 00:14:32,640 FOR SOME PROGRAM NEWS, AT BOTH 366 00:14:32,640 --> 00:14:35,880 NIH AND NCCIH, I WANT TO JUST 367 00:14:35,880 --> 00:14:41,480 GIVE A VERY QUICK UPDATE ON THE 368 00:14:41,480 --> 00:14:43,920 BRIDGE2AI PROJECT INITIATIVE 369 00:14:43,920 --> 00:14:45,720 THAT WE WERE HOPING TO HAVE SOME 370 00:14:45,720 --> 00:14:47,160 AWARDS ANNOUNCED AT THIS COUNCIL 371 00:14:47,160 --> 00:14:49,120 ROUND, BUT IT'S NOT GOING TO BE 372 00:14:49,120 --> 00:14:50,320 UNTIL MAY OR EARLY JUNE, SO 373 00:14:50,320 --> 00:14:52,080 WE'LL GIVE YOU AN UPDATE ON THIS 374 00:14:52,080 --> 00:14:58,000 IN SEPTEMBER. 375 00:14:58,000 --> 00:14:59,800 BUT HOWEVER, I AM DELIGHTED TO 376 00:14:59,800 --> 00:15:05,240 ANNOUNCE OUR AWARDEES FOR THE 377 00:15:05,240 --> 00:15:08,200 NEUROMECHANISMS OF FOR SPACE 378 00:15:08,200 --> 00:15:09,600 MANIPULATION, JOINED BY NCCIH 379 00:15:09,600 --> 00:15:11,600 AND THE NATIONAL INSTITUTES OF 380 00:15:11,600 --> 00:15:12,280 NEUROLOGICAL DISORDERS AND 381 00:15:12,280 --> 00:15:12,880 STROKE. 382 00:15:12,880 --> 00:15:15,080 THIS PROGRAM IS FOCUSING ON 383 00:15:15,080 --> 00:15:16,400 DEVELOPING INNOVATIVE AND 384 00:15:16,400 --> 00:15:19,320 IMPACTFUL RESOURCES TO ADVANCE 385 00:15:19,320 --> 00:15:21,080 OUR UNDERSTANDING OF BOTH NEURAL 386 00:15:21,080 --> 00:15:23,360 MECHANISMS AND BIOMECHANICS 387 00:15:23,360 --> 00:15:24,880 UNDERLYING FORCE-BASED 388 00:15:24,880 --> 00:15:25,240 MANIPULATION. 389 00:15:25,240 --> 00:15:29,880 SO YOU CAN SEE THE THREE AWARDS, 390 00:15:29,880 --> 00:15:31,960 SO THESE ARE THREE SEPARATE 391 00:15:31,960 --> 00:15:33,600 NETWORKS THAT WILL BE REALLY 392 00:15:33,600 --> 00:15:38,000 KIND OF ESTABLISHING GROUPS OF 393 00:15:38,000 --> 00:15:40,840 INVESTIGATORS TO REALLY GET THIS 394 00:15:40,840 --> 00:15:44,240 WHOLE FIELD KIND OF LAUNCHED. 395 00:15:44,240 --> 00:15:46,200 AND SOME GREAT NEWS FROM THE 396 00:15:46,200 --> 00:15:49,120 ALL-OF-US RESEARCH PROGRAM. 397 00:15:49,120 --> 00:15:54,520 THE NIH IS AWARDING $170 MILLION 398 00:15:54,520 --> 00:15:55,840 OVER FIVE YEARS PENDING THE 399 00:15:55,840 --> 00:15:57,040 AVAILABILITY OF FUNDS, OF 400 00:15:57,040 --> 00:15:59,120 COURSE, TO CLINICS AND CENTERS 401 00:15:59,120 --> 00:16:02,800 ACROSS THE COUNTRY FOR A NEW 402 00:16:02,800 --> 00:16:04,240 PRECISION NUTRITION STUDY THAT 403 00:16:04,240 --> 00:16:06,560 WILL DEVELOP ALGORITHMS TO 404 00:16:06,560 --> 00:16:09,840 PREDICT INDIVIDUAL RESPONSES TO 405 00:16:09,840 --> 00:16:12,440 FOODS AND ALSO DIETARY ROUTINES 406 00:16:12,440 --> 00:16:14,320 OR BEHAVIORS. 407 00:16:14,320 --> 00:16:16,720 SO THIS NUTRITION FOR PRECISION 408 00:16:16,720 --> 00:16:20,680 HEALTH IS THE FIRST EMBEDDED 409 00:16:20,680 --> 00:16:22,520 CLINICAL TRIAL IN THE ALL-OF-US 410 00:16:22,520 --> 00:16:23,120 RESEARCH PROGRAM. 411 00:16:23,120 --> 00:16:27,120 SO WE'VE OPINION BEEN EXPECW 412 00:16:27,120 --> 00:16:28,520 WITH QUITE TREPIDATION BECAUSE 413 00:16:28,520 --> 00:16:30,640 THE WHOLE POINT OF THE ALL-OF-US 414 00:16:30,640 --> 00:16:33,160 PROGRAM IS TO ENROLL LARGE 415 00:16:33,160 --> 00:16:36,120 NUMBERS OF HUMAN PARTICIPANTS, 416 00:16:36,120 --> 00:16:40,480 BUT ALSO -- AND COLLECT DATA TO 417 00:16:40,480 --> 00:16:42,200 ESTABLISH THIS VERY EXTENSIVE 418 00:16:42,200 --> 00:16:43,320 DATABASE, BUT ALSO TO ENABLE 419 00:16:43,320 --> 00:16:46,160 WHAT WE CALL ANCILLARY STUDIES 420 00:16:46,160 --> 00:16:49,480 TO THIS ENORMOUS DATABASE THAT 421 00:16:49,480 --> 00:16:50,640 WILL BE FUNDED SEPARATELY. 422 00:16:50,640 --> 00:16:51,640 AND THIS IS THE FIRST ONE OF 423 00:16:51,640 --> 00:16:54,280 THESE. 424 00:16:54,280 --> 00:16:57,960 WE ANTICIPATE A NUMBER OF U54, 425 00:16:57,960 --> 00:17:00,160 U24 AND UG1 PROJECTS FUNDED 426 00:17:00,160 --> 00:17:01,600 THROUGH THE NUTRITION FOR 427 00:17:01,600 --> 00:17:03,160 PRECISION HEALTH PROGRAM. 428 00:17:03,160 --> 00:17:06,040 NOW PRECISION NUTRITION, OF 429 00:17:06,040 --> 00:17:08,600 COURSE, ALIGNS VERY CLOSELY WITH 430 00:17:08,600 --> 00:17:12,640 NCCIH'S INTERESTS AND OUR VERY 431 00:17:12,640 --> 00:17:16,800 OWN CRAIG HOPP IS THE PROJECT 432 00:17:16,800 --> 00:17:19,000 SCIENTIST ON THE METABOLOMICS 433 00:17:19,000 --> 00:17:19,880 AND CLINICAL ASSAY CENTER. 434 00:17:19,880 --> 00:17:23,320 NOW ALSO, NEARLY 100,000 HIGHLY 435 00:17:23,320 --> 00:17:26,800 DIVERSE WHOLE GENOME SEQUENCES 436 00:17:26,800 --> 00:17:30,040 ALONG WITH A WEALTH OF 437 00:17:30,040 --> 00:17:34,120 ASSOCIATED PHENOTYPIC DATA FROM 438 00:17:34,120 --> 00:17:37,320 ELECTRONIC HEALTH RECORDS, 439 00:17:37,320 --> 00:17:38,520 WEARABLES, SURVEY DATA ARE 440 00:17:38,520 --> 00:17:39,600 AVAILABLE THROUGH THE ALL-OF-US 441 00:17:39,600 --> 00:17:41,160 RESEARCH PROGRAM. 442 00:17:41,160 --> 00:17:42,680 THIS IS OPEN TO ANYONE WHO WANTS 443 00:17:42,680 --> 00:17:44,640 TO ACCESS IT. 444 00:17:44,640 --> 00:17:48,800 50% OF THESE DATA IS FROM -- I 445 00:17:48,800 --> 00:17:54,400 MEAN INVESTIGATORS -- FROM 446 00:17:54,400 --> 00:17:55,840 INDIVIDUALS -- 50% OF THE DATA 447 00:17:55,840 --> 00:17:57,240 IS FROM INDIVIDUALS WHO IDENTIFY 448 00:17:57,240 --> 00:17:59,440 WITH RACIAL OR ETHNIC GROUPS 449 00:17:59,440 --> 00:18:02,080 THAT HAVE HISTORICALLY BEEN 450 00:18:02,080 --> 00:18:03,720 UNDERREPRESENTED IN RESEARCH. 451 00:18:03,720 --> 00:18:09,120 SO YOU CAN SEE HERE THE LARGE 452 00:18:09,120 --> 00:18:14,200 NUMBERS OF GENOME SEQUENCES THAT 453 00:18:14,200 --> 00:18:15,720 WILL BE ASSOCIATED WITH EACH OF 454 00:18:15,720 --> 00:18:16,600 THE VARIOUS DIFFERENT TYPES OF 455 00:18:16,600 --> 00:18:21,840 DATA. 456 00:18:21,840 --> 00:18:23,480 WE ARE VERY MUCH LOOKING FORWARD 457 00:18:23,480 --> 00:18:26,640 TO SOME ANTICIPATED FUNDING OF 458 00:18:26,640 --> 00:18:28,080 OPPORTUNITY ANNOUNCEMENTS 459 00:18:28,080 --> 00:18:29,880 REGARDING ADDITIONAL ANCILLARY 460 00:18:29,880 --> 00:18:31,920 STUDIES. 461 00:18:31,920 --> 00:18:35,280 ANOTHER VERY, VERY IMPORTANT 462 00:18:35,280 --> 00:18:37,400 AREA THAT'S REALLY GETTING A LOT 463 00:18:37,400 --> 00:18:39,120 OF ATTENTION NIH-WIDE IS 464 00:18:39,120 --> 00:18:41,320 MATERNAL MORTALITY. 465 00:18:41,320 --> 00:18:46,160 WE KNOW ESPECIALLY THAT THERE IS 466 00:18:46,160 --> 00:18:49,640 TWO TO THREE TIMES MORE 467 00:18:49,640 --> 00:18:50,960 LIKELY -- MORTALITY IS 23 TIMES 468 00:18:50,960 --> 00:18:52,720 MORE LIKELY IN AMERICAN INDIAN, 469 00:18:52,720 --> 00:18:55,440 ALASKA NATIVE AND BLACK WOMEN, 470 00:18:55,440 --> 00:18:57,640 THE MORTALITY RATE FROM A 471 00:18:57,640 --> 00:18:58,600 PREGNANCY-RELATED CAUSE, THAN IN 472 00:18:58,600 --> 00:19:03,080 WHITE WOMEN. 473 00:19:03,080 --> 00:19:05,640 SO THIS IS A HUGE PRIORITY AT 474 00:19:05,640 --> 00:19:07,680 NIH AND MULTIPLE ICS HAVE 475 00:19:07,680 --> 00:19:09,680 INVESTED IN RESEARCH TO PREVENT 476 00:19:09,680 --> 00:19:12,400 MORBIDITY AND MORTALITY AND 477 00:19:12,400 --> 00:19:13,360 OVERALL HEALTH OF PREGNANT 478 00:19:13,360 --> 00:19:13,840 WOMEN. 479 00:19:13,840 --> 00:19:15,040 SO AT NCCIH, WE'RE WATCHING THIS 480 00:19:15,040 --> 00:19:16,560 SPACE VERY CLOSELY, AND WE'RE 481 00:19:16,560 --> 00:19:17,640 KEEPING OUR FINGER ON THE PULSE 482 00:19:17,640 --> 00:19:20,040 OF THESE NIH-WIDE PROJECTS AND 483 00:19:20,040 --> 00:19:23,240 WE'LL LET YOU KNOW WHEN FUNDING 484 00:19:23,240 --> 00:19:26,400 OPPORTUNITY ANNOUNCEMENTS ARE 485 00:19:26,400 --> 00:19:27,640 AVAILABLE FOR IMPLEMENTATION 486 00:19:27,640 --> 00:19:29,120 RESEARCH IN THIS VERY IMPORTANT 487 00:19:29,120 --> 00:19:29,800 AREA. 488 00:19:29,800 --> 00:19:31,440 WE'RE PARTICULARLY INTERESTED IN 489 00:19:31,440 --> 00:19:32,440 COMPLEMENTARY HEALTH APPROACHES 490 00:19:32,440 --> 00:19:34,840 FOR MANAGING THE VARIOUS 491 00:19:34,840 --> 00:19:36,200 DIFFERENT ASPECTS OF PREGNANCY 492 00:19:36,200 --> 00:19:39,960 THAT COULD LEAD TO IMPROVED 493 00:19:39,960 --> 00:19:41,200 HEALTH OUTCOMES FOR PREGNANT 494 00:19:41,200 --> 00:19:45,880 WOMEN. 495 00:19:45,880 --> 00:19:47,400 NOW AS I'VE PRETTY MUCH BEEN 496 00:19:47,400 --> 00:19:48,600 DOING FOR THE LAST TWO YEARS, 497 00:19:48,600 --> 00:19:49,920 GIVING YOU A LITTLE BIT OF 498 00:19:49,920 --> 00:19:52,160 UPDATES ON WHAT'S HAPPENING IN 499 00:19:52,160 --> 00:19:54,320 THE AREA OF COVID. 500 00:19:54,320 --> 00:20:00,440 ONE VERY IMPORTANT INITIATIVE IS 501 00:20:00,440 --> 00:20:02,400 THE ROSALIND TRACKER. 502 00:20:02,400 --> 00:20:03,160 THIS IS VERY IMPORTANT BECAUSE 503 00:20:03,160 --> 00:20:04,840 IT'S A REALTIME TRACKER TO 504 00:20:04,840 --> 00:20:10,480 SUPPORT THE RAPID GENOTYPING FOR 505 00:20:10,480 --> 00:20:12,160 SARS-COV-2. 506 00:20:12,160 --> 00:20:13,840 THE CURRENT SITUATION RIGHT NOW 507 00:20:13,840 --> 00:20:15,360 IS MOST OF THE PRIMARY METHOD 508 00:20:15,360 --> 00:20:21,280 FOR DETECTING VARIANTS IS NEXT 509 00:20:21,280 --> 00:20:21,760 GEN SEQUENCING. 510 00:20:21,760 --> 00:20:22,920 THE PROBLEM WITH THIS FIRST OF 511 00:20:22,920 --> 00:20:24,960 ALL IS IT'S EXPENSIVE AND IT CAN 512 00:20:24,960 --> 00:20:26,400 TAKE MANY WEEKS BEFORE 513 00:20:26,400 --> 00:20:27,720 SEQUENCING DATA IS AVAILABLE IN 514 00:20:27,720 --> 00:20:29,560 PUBLIC DATA REPOSITORIES. 515 00:20:29,560 --> 00:20:30,880 THE ROSALIND TRACKER IS VERY 516 00:20:30,880 --> 00:20:31,840 NOVEL AND IMPORTANT BECAUSE IT 517 00:20:31,840 --> 00:20:35,040 USES A PCR-BASED GENOTYPING 518 00:20:35,040 --> 00:20:36,880 APPROACH THAT REALLY IS VERY, 519 00:20:36,880 --> 00:20:37,360 VERY QUICK. 520 00:20:37,360 --> 00:20:39,000 IT CAN BE IMPLEMENTED IN ANY 521 00:20:39,000 --> 00:20:41,400 TESTING LAB THAT PERFORMS PCR, 522 00:20:41,400 --> 00:20:43,480 AND IT'S SIGNIFICANTLY LESS 523 00:20:43,480 --> 00:20:43,880 EXPENSIVE. 524 00:20:43,880 --> 00:20:46,640 SO YOU CAN SEE HERE FROM THE BAR 525 00:20:46,640 --> 00:20:49,880 GRAPH THAT OVER THE LAST 60 526 00:20:49,880 --> 00:20:54,040 DAYS, THE BA2, BA3 VARIANT HAS 527 00:20:54,040 --> 00:20:55,520 BECOME DOMINANT OVER THE OTHER 528 00:20:55,520 --> 00:20:56,720 OMICRON VARIANTS, BUT HOWEVER, 529 00:20:56,720 --> 00:20:58,000 THERE'S SOME VARIATION BY STATE. 530 00:20:58,000 --> 00:20:58,880 SO IT'S REALLY IMPORTANT THAT WE 531 00:20:58,880 --> 00:21:00,400 HAVE METHODS THAT ARE ABLE TO 532 00:21:00,400 --> 00:21:02,160 REALLY DETECT THIS IN REALTIME 533 00:21:02,160 --> 00:21:04,040 AS THESE VARIANTS ARE SORT OF, 534 00:21:04,040 --> 00:21:05,640 YOU KNOW, POPPING UP AND 535 00:21:05,640 --> 00:21:07,000 SPREADING. 536 00:21:07,000 --> 00:21:08,360 SO THIS RESEARCH IS SUPPORTED 537 00:21:08,360 --> 00:21:12,640 WITH FUNDING FROM NIBIB AS PART 538 00:21:12,640 --> 00:21:14,320 OF THE RAPID ACCELERATION OF 539 00:21:14,320 --> 00:21:17,920 DIAGNOSTICS OR RADX INITIATIVE. 540 00:21:17,920 --> 00:21:21,120 NOW, IN MARCH, THE FDA 541 00:21:21,120 --> 00:21:22,520 AUTHORIZED A FOURTH DOSE OR THE 542 00:21:22,520 --> 00:21:26,800 SECOND BOOSTER OF PFIZER AND 543 00:21:26,800 --> 00:21:28,440 OTHER -- AND MODERNA VACCINES 544 00:21:28,440 --> 00:21:30,760 AND OTHER VACCINES FOR OLDER AND 545 00:21:30,760 --> 00:21:32,600 CERTAIN IMMUNOCOMPROMISED 546 00:21:32,600 --> 00:21:33,520 POPULATIONS. 547 00:21:33,520 --> 00:21:35,960 AND THE NEW ENGLAND JOURNAL OF 548 00:21:35,960 --> 00:21:39,080 MEDICINE STUDY THAT WAS 549 00:21:39,080 --> 00:21:40,000 PUBLISHED RECENTLY FROM A 550 00:21:40,000 --> 00:21:41,720 RESEARCH GROUP IN ISRAEL, VERY 551 00:21:41,720 --> 00:21:43,800 CONVINCINGLY SHOWED THAT A 552 00:21:43,800 --> 00:21:44,440 SECOND BOOSTER SIGNIFICANTLY 553 00:21:44,440 --> 00:21:46,840 DECREASES THE LIKELIHOOD OF 554 00:21:46,840 --> 00:21:47,920 HOSPITALIZATION, SEVERE 555 00:21:47,920 --> 00:21:48,680 INFECTION AND DEATH. 556 00:21:48,680 --> 00:21:50,880 YOU CAN SEE THESE CURVES, THE 557 00:21:50,880 --> 00:21:51,880 DIFFERENCE BETWEEN THE RED AND 558 00:21:51,880 --> 00:21:53,400 THE BLUE LINES ARE VERY 559 00:21:53,400 --> 00:21:54,400 CONVINCING. 560 00:21:54,400 --> 00:21:56,800 SO IF THERE WAS EVER ANY DOUBT 561 00:21:56,800 --> 00:21:58,120 THAT THESE BOOSTERS ARE DOING 562 00:21:58,120 --> 00:22:02,080 SOMETHING, REALLY THIS IS IT. 563 00:22:02,080 --> 00:22:06,040 NOW, A NEW NATIONWIDE TEST TO 564 00:22:06,040 --> 00:22:07,440 TREAT INITIATIVE, THIS IS VERY 565 00:22:07,440 --> 00:22:09,400 IMPORTANT, WAS ALSO LAUNCHED IN 566 00:22:09,400 --> 00:22:11,080 MARCH BY THE BIDEN-HARRIS 567 00:22:11,080 --> 00:22:12,600 ADMINISTRATION TO ALLOW 568 00:22:12,600 --> 00:22:15,760 INDIVIDUALS TO QUICKLY ACCESS 569 00:22:15,760 --> 00:22:17,080 FREE LIFE SAVING TREATMENTS FOR 570 00:22:17,080 --> 00:22:17,920 COVID-19. 571 00:22:17,920 --> 00:22:20,240 SO THIS TEST TO TREAT PROGRAM 572 00:22:20,240 --> 00:22:23,320 MEANS THAT IF YOU GO TO A 573 00:22:23,320 --> 00:22:24,560 CERTAIN AREA, PLACE TO BE 574 00:22:24,560 --> 00:22:28,400 TESTED, FOR EXAMPLE, AT CERTAIN 575 00:22:28,400 --> 00:22:31,320 PHARMACIES OR HEALTH RESOURCES 576 00:22:31,320 --> 00:22:32,320 SERVICE ADMINISTRATION SUPPORTED 577 00:22:32,320 --> 00:22:33,960 FEDERALLY QUALIFIED HEALTH 578 00:22:33,960 --> 00:22:36,360 CENTERS, THEN YOU CAN -- IF YOU 579 00:22:36,360 --> 00:22:39,400 TEST POSITIVE AND TREATMENTS ARE 580 00:22:39,400 --> 00:22:41,600 APPROPRIATE, YOU CAN RECEIVE A 581 00:22:41,600 --> 00:22:42,680 PRESCRIPTION FROM A HEALTHCARE 582 00:22:42,680 --> 00:22:44,120 PROVIDER RIGHT THERE ON THE SPOT 583 00:22:44,120 --> 00:22:45,600 AND HAVE PRESCRIPTIONS FILLED AT 584 00:22:45,600 --> 00:22:47,000 THAT LOCATION. 585 00:22:47,000 --> 00:22:48,600 THESE ARE AT PHARMACY-BASED 586 00:22:48,600 --> 00:22:49,920 CLINICS THAT HAVE THESE KINDS OF 587 00:22:49,920 --> 00:22:50,280 FACILITIES. 588 00:22:50,280 --> 00:22:53,840 BUT THIS IS GOING TO BE VERY 589 00:22:53,840 --> 00:22:57,600 IMPORTANT GOING FORWARD TO MAKE 590 00:22:57,600 --> 00:22:58,720 SURE THAT WE TAKE FULL ADVANTAGE 591 00:22:58,720 --> 00:23:00,240 OF THE KIND OF LIFE SAVING 592 00:23:00,240 --> 00:23:03,600 MEDICATIONS THAT WE NOW HAVE. 593 00:23:03,600 --> 00:23:06,280 NOW ANOTHER VERY IMPORTANT 594 00:23:06,280 --> 00:23:08,720 COURSE OF THIS PANDEMIC IS POST 595 00:23:08,720 --> 00:23:11,600 COVID, OR WHAT WE CALL PAS, POST 596 00:23:11,600 --> 00:23:13,480 COVID SEQUELAE OR LONG COVID. 597 00:23:13,480 --> 00:23:15,880 WE KNOW THAT RECOVERY FROM 598 00:23:15,880 --> 00:23:17,080 SARS-COV-2 INFECTION IS 599 00:23:17,080 --> 00:23:17,640 EXTREMELY VARIABLE. 600 00:23:17,640 --> 00:23:19,720 MANY PATIENTS RECOVER VERY 601 00:23:19,720 --> 00:23:21,240 QUICKLY AND HAVE MINIMAL 602 00:23:21,240 --> 00:23:27,040 SYMPTOMS, BUT OTHERS REALLY HAVE 603 00:23:27,040 --> 00:23:28,040 PROMINENT SYMPTOMS THAT CAN 604 00:23:28,040 --> 00:23:31,240 CONTINUE ON FOR QUITE A WHILE, 605 00:23:31,240 --> 00:23:32,320 INVOLVING MULTIPLE ORGAN SYSTEMS 606 00:23:32,320 --> 00:23:34,160 AND REALLY CAN SIGNIFICANTLY 607 00:23:34,160 --> 00:23:36,240 AFFECT QUALITY OF LIFE. 608 00:23:36,240 --> 00:23:39,120 SO THE MAGNITUDE OF THE PUBLIC 609 00:23:39,120 --> 00:23:40,960 HEALTH IMPACT OF THESE SEQUELAE 610 00:23:40,960 --> 00:23:42,320 IS POTENTIALLY VERY LARGE, GIVEN 611 00:23:42,320 --> 00:23:44,120 THE NUMBER OF INDIVIDUALS ACROSS 612 00:23:44,120 --> 00:23:46,560 ALL THE AGE SPECTRUMS THAT HAVE 613 00:23:46,560 --> 00:23:47,960 ALREADY BEEN AFFECTED AND WILL 614 00:23:47,960 --> 00:23:49,200 CONTINUE PROBABLY TO BE INFECTED 615 00:23:49,200 --> 00:23:51,080 WITH SARS-COV-2. 616 00:23:51,080 --> 00:23:52,960 SO THIS REQUEST FOR APPLICATIONS 617 00:23:52,960 --> 00:23:56,560 IS TO SOLICIT APPLICATIONS 618 00:23:56,560 --> 00:23:57,880 PROPOSING CLINICAL TRIAL 619 00:23:57,880 --> 00:24:00,280 PROTOCOLS TO BE FINALIZED AND 620 00:24:00,280 --> 00:24:02,360 EXECUTED RAPIDLY FOR THE 621 00:24:02,360 --> 00:24:03,480 IDENTIFICATION OF SAFE AND 622 00:24:03,480 --> 00:24:05,720 EFFECTIVE TREATMENTS AND 623 00:24:05,720 --> 00:24:07,400 PREVENTIVE STRATEGIES VERY 624 00:24:07,400 --> 00:24:09,480 IMPORTANTLY FOR PASC IN THOSE 625 00:24:09,480 --> 00:24:10,680 OVER 18 YEARS OF AGE. 626 00:24:10,680 --> 00:24:14,320 WE ANTICIPATE FURTHER 627 00:24:14,320 --> 00:24:15,600 OPPORTUNITIES FOR TRIALS 628 00:24:15,600 --> 00:24:17,240 INVOLVING CHILDREN. 629 00:24:17,240 --> 00:24:18,680 SO WE'RE REALLY INTERESTED OF 630 00:24:18,680 --> 00:24:22,160 COURSE IN THIS AREA FROM POINT 631 00:24:22,160 --> 00:24:23,720 OF VIEW OF CHRONIC STRESS AND 632 00:24:23,720 --> 00:24:27,000 STRESS MANAGEMENT AND BEHAVIORAL 633 00:24:27,000 --> 00:24:29,520 INTERVENTIONS THAT CAN HELP TO 634 00:24:29,520 --> 00:24:34,320 SORT OF STRENGTHEN OVERALL 635 00:24:34,320 --> 00:24:35,280 HEALTH, BECAUSE WE THINK THIS IS 636 00:24:35,280 --> 00:24:36,640 VERY IMPORTANT. 637 00:24:36,640 --> 00:24:37,160 OUR OVERALL HEALTH AND THE 638 00:24:37,160 --> 00:24:38,160 FUNCTION OF OUR IMMUNE SYSTEMS 639 00:24:38,160 --> 00:24:40,480 IS NOT JUST AN ISOLATED EVENT. 640 00:24:40,480 --> 00:24:45,720 IT REALLY FENDS ON A LOT OF 641 00:24:45,720 --> 00:24:49,000 FACTORS THAT ARE INFLUENCED BY 642 00:24:49,000 --> 00:24:51,200 SELF-CARE AND ATTENTION TO 643 00:24:51,200 --> 00:24:53,160 NUTRITIONAL, PSYCHOLOGICAL, 644 00:24:53,160 --> 00:24:54,360 PHYSICAL, ET CETERA, KIND OF 645 00:24:54,360 --> 00:24:54,920 ASPECTS OF HEALTH. 646 00:24:54,920 --> 00:24:56,680 SO WE THINK THIS IS GOING TO BE 647 00:24:56,680 --> 00:24:59,000 VERY, VERY IMPORTANT. 648 00:24:59,000 --> 00:25:03,920 I ALSO WANT TO HIGHLIGHT SOME 649 00:25:03,920 --> 00:25:06,040 RESEARCH, SOME RECENT 650 00:25:06,040 --> 00:25:07,640 PUBLICATIONS INCLUDING SEVERAL 651 00:25:07,640 --> 00:25:09,200 PAPERS FROM OUR CURRENT AND PAST 652 00:25:09,200 --> 00:25:15,080 INTRAMURAL RESEARCHERS, 653 00:25:15,080 --> 00:25:15,960 ESPECIALLY RICHARD -- AS WELL AS 654 00:25:15,960 --> 00:25:18,600 LAURA CASE WHO WAS PREVIOUSLY A 655 00:25:18,600 --> 00:25:19,720 POSTDOCTORAL FELLOW, NOW 656 00:25:19,720 --> 00:25:22,320 ASSISTANT PROFESSOR AT U.C. 657 00:25:22,320 --> 00:25:22,600 SAN DIEGO. 658 00:25:22,600 --> 00:25:23,640 AND SO IF YOU HAVE A CHANCE TO 659 00:25:23,640 --> 00:25:24,840 CHECK THESE OUT, THESE ARE ALL 660 00:25:24,840 --> 00:25:29,200 IN YOUR PACKET. 661 00:25:29,200 --> 00:25:30,760 AND I ALSO WANT TO POINT OUT 662 00:25:30,760 --> 00:25:31,960 THIS STUDY FROM UNIVERSITY OF 663 00:25:31,960 --> 00:25:33,720 WASHINGTON IN SEATTLE, WHERE 664 00:25:33,720 --> 00:25:35,600 RESEARCHERS LOOKED AT WHETHER OR 665 00:25:35,600 --> 00:25:38,560 NOT RESIDENTIAL GREEN SPACES ARE 666 00:25:38,560 --> 00:25:41,280 ASSOCIATED WITH A RISK OF 667 00:25:41,280 --> 00:25:42,400 DEMENTIA AMONG OLDER ADULTS. 668 00:25:42,400 --> 00:25:47,720 THIS WAS A STUDY, AN ANCILLARY 669 00:25:47,720 --> 00:25:49,480 STUDY FROM THE GINKGO EVALUATION 670 00:25:49,480 --> 00:25:52,760 OF MEMORY STUDY, THE GEM STUDY, 671 00:25:52,760 --> 00:25:54,080 WHERE 3,000 PARTICIPANTS 75 OR 672 00:25:54,080 --> 00:25:57,360 OLDER WERE ENROLLED BETWEEN 2000 673 00:25:57,360 --> 00:25:58,800 AND 2008. 674 00:25:58,800 --> 00:26:00,560 AND THEY WERE ABLE TO GO BACK 675 00:26:00,560 --> 00:26:03,320 AND LOOK AT ASSOCIATIONS BETWEEN 676 00:26:03,320 --> 00:26:07,160 THE GREEN AREAS, GREENSPACE 677 00:26:07,160 --> 00:26:08,080 SURROUNDING WHERE PEOPLE LIVE 678 00:26:08,080 --> 00:26:10,440 AND WERE ABLE TO CONTROL FOR 679 00:26:10,440 --> 00:26:13,640 MULTIPLE FACTORS, INCLUDING 680 00:26:13,640 --> 00:26:15,240 SOCIAL -- NEIGHBORHOOD 681 00:26:15,240 --> 00:26:15,720 SOCIOECONOMIC STATUS. 682 00:26:15,720 --> 00:26:18,080 WHAT THEY FOUND IS THAT EVIDENCE 683 00:26:18,080 --> 00:26:19,680 FOR ASSOCIATION BETWEEN THE 684 00:26:19,680 --> 00:26:21,520 GREENSPACES AND ALL CAUSE 685 00:26:21,520 --> 00:26:22,640 DEMENTIA SUGGESTING THAT 686 00:26:22,640 --> 00:26:24,800 GREENSPACES MAY ACTUALLY BE 687 00:26:24,800 --> 00:26:25,120 PROTECTIVE. 688 00:26:25,120 --> 00:26:27,680 SO IT WILL BE INTERESTING TO 689 00:26:27,680 --> 00:26:28,960 FOLLOW HOW THIS KIND OF RESEARCH 690 00:26:28,960 --> 00:26:33,360 EVOLVES. 691 00:26:33,360 --> 00:26:38,400 THIS IS YOU A 'NOTHER ANG 692 00:26:38,400 --> 00:26:39,920 STUDY WHERE RESEARCHERS SHOW 693 00:26:39,920 --> 00:26:42,000 THAT GUT MICROBIOME, DIVERSITY 694 00:26:42,000 --> 00:26:43,200 AND ABUNDANCE CORRELATES WITH 695 00:26:43,200 --> 00:26:46,120 GREY MATTER VOLUME IN THE 696 00:26:46,120 --> 00:26:52,160 HIPPOCAMPUS AND NUCLEUS 697 00:26:52,160 --> 00:26:54,080 ACCUMBENS IN OLDER ADULTS WITH 698 00:26:54,080 --> 00:26:54,480 DEPRESSION. 699 00:26:54,480 --> 00:26:55,680 SO LOOKING ACROSS THE DIFFERENT 700 00:26:55,680 --> 00:26:57,120 SYSTEMS OF THE BODY, THIS TIME 701 00:26:57,120 --> 00:26:59,520 THE GUT AND THE BRAIN, AND 702 00:26:59,520 --> 00:27:01,400 ALTHOUGH THIS WAS AL SMALL 703 00:27:01,400 --> 00:27:03,040 STUDY, THE DATA SUGGESTS THAT 704 00:27:03,040 --> 00:27:07,320 THE GUT MICROBIOME MAY REFLECT 705 00:27:07,320 --> 00:27:10,040 AND INFLUENCE BRAIN HEALTH IN 706 00:27:10,040 --> 00:27:10,840 GERIATRIC DEPRESSION. 707 00:27:10,840 --> 00:27:14,320 THE STUDY WAS PARTIALLY FUNDED 708 00:27:14,320 --> 00:27:18,360 BY NCCIH AND WITH A K24 AWARD TO 709 00:27:18,360 --> 00:27:25,400 HELY LEF 710 00:27:25,400 --> 00:27:27,560 HELEN LAVRETSKY. 711 00:27:27,560 --> 00:27:29,200 INCREASING CONSUMPTION OF ORAL 712 00:27:29,200 --> 00:27:36,040 SUPPLEMENTS MADE FROM KRATOM 713 00:27:36,040 --> 00:27:37,000 LEAVES IS VERY MUCH ON THE RISE 714 00:27:37,000 --> 00:27:42,480 IN TERMS OF PEOPLE USING THESE 715 00:27:42,480 --> 00:27:44,360 HERBS AND HERBAL DERIVATIVES TO 716 00:27:44,360 --> 00:27:47,400 MANAGE OPIOID WITHDRAWAL 717 00:27:47,400 --> 00:27:48,600 SYMPTOMS IN THE EAST, FOR 718 00:27:48,600 --> 00:27:50,600 EXAMPLE, INDONESIA, VERY MUCH 719 00:27:50,600 --> 00:27:53,200 EVERYBODY WHO HAS A BACKYARD HAS 720 00:27:53,200 --> 00:27:56,160 A KRATOM TREE. 721 00:27:56,160 --> 00:27:57,360 AND PEOPLE PICK THE LEAVES AND 722 00:27:57,360 --> 00:27:58,560 DRINK IT AS TEA. 723 00:27:58,560 --> 00:27:59,760 IT'S VERY, VERY COMMON. 724 00:27:59,760 --> 00:28:04,360 AND THIS HAS BEEN USED IN THIS 725 00:28:04,360 --> 00:28:05,280 COUNTRY FOR WITHDRAWAL SYMPTOMS 726 00:28:05,280 --> 00:28:07,120 AND PAIN, BUT UNFORTUNATELY, 727 00:28:07,120 --> 00:28:10,080 THIS IS LEADING TO INCREASED 728 00:28:10,080 --> 00:28:11,920 KRATOM-LINKED OVERDOSES AND 729 00:28:11,920 --> 00:28:12,120 DEATH. 730 00:28:12,120 --> 00:28:14,560 SO WE NEED TO UNDERSTAND WHAT'S 731 00:28:14,560 --> 00:28:14,880 GOING ON. 732 00:28:14,880 --> 00:28:19,400 IN THIS STUDY FROM MARY PAINE'S 733 00:28:19,400 --> 00:28:20,600 GROUP, UNIVERSITY OF SEATTLE IN 734 00:28:20,600 --> 00:28:23,840 WASHINGTON, THE TEAM PERFORMED A 735 00:28:23,840 --> 00:28:25,400 COMPREHENSIVE PHARMACOKINETIC 736 00:28:25,400 --> 00:28:28,000 CHARACTERIZATION OF KRATOM 737 00:28:28,000 --> 00:28:31,200 ALKALOIDS IN SIX HEALTHY ADULTS 738 00:28:31,200 --> 00:28:34,040 WHO WERE ADMINISTERED A SINGLE 739 00:28:34,040 --> 00:28:35,680 LOW DOSE WELL CHARACTERIZED 740 00:28:35,680 --> 00:28:37,520 KRATOM PRODUCT AS A TEA, WHICH 741 00:28:37,520 --> 00:28:39,880 IS THE MOST COMMON ROUTE OF 742 00:28:39,880 --> 00:28:40,360 CONSUMPTION WORLDWIDE. 743 00:28:40,360 --> 00:28:42,080 THIS IS A REALLY IMPORTANT 744 00:28:42,080 --> 00:28:43,000 RESULT TO OPEN THE DOOR TO FUEL 745 00:28:43,000 --> 00:28:44,760 TOUR STUDIES THAT WILL ENABLE 746 00:28:44,760 --> 00:28:45,960 REGULATORY AGENCIES TO MAKE 747 00:28:45,960 --> 00:28:46,920 INFORMED DECISIONS ABOUT THE 748 00:28:46,920 --> 00:28:50,360 SAFE USE OF THIS INCREASINGLY 749 00:28:50,360 --> 00:28:52,200 POPULAR BOTANICAL PRODUCT AND 750 00:28:52,200 --> 00:28:52,960 ADDRESSING IMPORTANT PUBLIC 751 00:28:52,960 --> 00:28:53,400 HEALTH CONCERNS. 752 00:28:53,400 --> 00:28:54,960 THIS WAS FUNDED BY NCCIH AND 753 00:28:54,960 --> 00:28:57,120 ODS. 754 00:28:57,120 --> 00:28:58,640 I WOULD ALSO LIKE TO MENTION A 755 00:28:58,640 --> 00:29:01,040 VERY EXCITING STUDY FROM 756 00:29:01,040 --> 00:29:03,440 DR. ERIC GARLAND'S GROUP, 757 00:29:03,440 --> 00:29:05,560 SUCCESSFUL TREATMENT OF OPIOID 758 00:29:05,560 --> 00:29:06,680 MISUSE AMONG PEOPLE WITH CHRONIC 759 00:29:06,680 --> 00:29:09,160 PAIN WHICH IS, AS WE KNOW, VERY 760 00:29:09,160 --> 00:29:10,120 CHALLENGING. 761 00:29:10,120 --> 00:29:13,200 THIS IS A NIDA-FUNDED RANDOMIZED 762 00:29:13,200 --> 00:29:15,160 CONTROLLED TRIAL WHERE 763 00:29:15,160 --> 00:29:16,160 DR. GARLAND'S GROUP SHOWED THAT 764 00:29:16,160 --> 00:29:18,000 THE MINDFULNESS ORIENTED 765 00:29:18,000 --> 00:29:20,360 RECOVERY ENHANCEMENT OR MORE 766 00:29:20,360 --> 00:29:30,880 INTERVENTION LED TO SUSTAINED -- 767 00:29:33,880 --> 00:29:35,040 SO VERY IMPORTANT RESULTS. 768 00:29:35,040 --> 00:29:36,880 JUST WANT TO GO THROUGH SOME 769 00:29:36,880 --> 00:29:39,280 NCCIH FUNDING OPPORTUNITIES. 770 00:29:39,280 --> 00:29:41,480 I'M GOING TO START WITH A -- 771 00:29:41,480 --> 00:29:43,680 ACTUALLY IT'S NOT FUNDING BUT 772 00:29:43,680 --> 00:29:47,080 THIS IS A REQUEST FOR 773 00:29:47,080 --> 00:29:49,240 INFORMATION, OR RFI, TO IDENTIFY 774 00:29:49,240 --> 00:29:52,960 A SET OF DETERMINANTS FOR WHOLE 775 00:29:52,960 --> 00:29:53,600 PERSON HEALTH. 776 00:29:53,600 --> 00:29:54,600 NOW WE'RE VERY INTERESTED IN 777 00:29:54,600 --> 00:29:57,200 THIS, VERY EXCITED ABOUT THIS 778 00:29:57,200 --> 00:29:58,760 RFI, BECAUSE THIS IS REALLY A 779 00:29:58,760 --> 00:29:59,640 FOLLOW-UP FROM A LOT OF THE 780 00:29:59,640 --> 00:30:02,440 INFORMATIONS 781 00:30:02,440 --> 00:30:04,640 CONVERSATIONS WE'VE BEEN HAVING 782 00:30:04,640 --> 00:30:06,040 AT NCCIH THROUGHOUT OUR WHOLE 783 00:30:06,040 --> 00:30:07,840 PERSON BOTH INTERNAL AND 784 00:30:07,840 --> 00:30:09,360 EXTERNAL WORKING GROUPS AS WELL 785 00:30:09,360 --> 00:30:10,800 AS COUNCIL, INPUT THAT WE HAVE 786 00:30:10,800 --> 00:30:12,280 GOTTEN FROM ALL OF YOU IN TERMS 787 00:30:12,280 --> 00:30:15,040 OF THE IMPORTANCE OF 788 00:30:15,040 --> 00:30:18,680 UNDERSTANDING THE FACTORS THAT 789 00:30:18,680 --> 00:30:19,440 INFLUENCE WHOLE PERSON HEALTH. 790 00:30:19,440 --> 00:30:20,960 THIS IS NOT A SIMPLE THING. 791 00:30:20,960 --> 00:30:21,920 YOU CAN IMAGINE, WHAT WE'RE 792 00:30:21,920 --> 00:30:25,760 GOING TO BE ASKING FOR IN THIS 793 00:30:25,760 --> 00:30:27,760 RFI, AND I HOPE THAT ALL OF YOU 794 00:30:27,760 --> 00:30:31,240 EITHER HAVE BEEN OR WILL 795 00:30:31,240 --> 00:30:32,560 HOPEFULLY RECEIVE EMAILS ABOUT 796 00:30:32,560 --> 00:30:34,000 THIS. 797 00:30:34,000 --> 00:30:35,960 WE'VE ALSO REALLY KIND OF BEEN 798 00:30:35,960 --> 00:30:38,120 BLASTING THIS FOR ALL OF OUR 799 00:30:38,120 --> 00:30:38,800 COMMUNICATION CHANNELS. 800 00:30:38,800 --> 00:30:40,320 WHAT WE'RE ASKING PEOPLE IS TO 801 00:30:40,320 --> 00:30:46,080 GIVE A LIST OF 20 FACTORS THAT 802 00:30:46,080 --> 00:30:48,880 INFLUENCE WHOLE PERSON HEALTH, 803 00:30:48,880 --> 00:30:49,880 INCLUDING ALL OF THE DIFFERENT 804 00:30:49,880 --> 00:30:51,520 DOMAINS. 805 00:30:51,520 --> 00:30:52,440 BIOLOGICAL, BEHAVIORAL, SOCIAL 806 00:30:52,440 --> 00:30:52,840 AND ENVIRONMENTAL. 807 00:30:52,840 --> 00:30:57,120 WE PICKED THE NUMBER 20 808 00:30:57,120 --> 00:31:00,640 ARBITRARILY, BASICALLY BECAUSE O 809 00:31:00,640 --> 00:31:02,760 MUCH, AND SO WE KIND OF SHOT 810 00:31:02,760 --> 00:31:04,160 SOMEWHERE IN THE MIDDLE, AND 811 00:31:04,160 --> 00:31:05,560 IT'S NOT GOING TO BE THE FINAL 812 00:31:05,560 --> 00:31:07,320 NUMBER OBVIOUSLY, WE'RE GOING TO 813 00:31:07,320 --> 00:31:08,520 SEE WHAT INPUT WE GET. 814 00:31:08,520 --> 00:31:10,040 BUT WE REALLY WANT TO TRY TO 815 00:31:10,040 --> 00:31:11,600 DEFINE, WHAT ARE THE MAIN 816 00:31:11,600 --> 00:31:13,400 FACTORS IF YOU HAD TO NAME 20 817 00:31:13,400 --> 00:31:16,200 FACTORS THAT ARE REALLY MOST 818 00:31:16,200 --> 00:31:17,040 IMPORTANT, WHAT WOULD THEY BE? 819 00:31:17,040 --> 00:31:19,280 SO THIS IS AN EXPERIMENT. 820 00:31:19,280 --> 00:31:20,880 WE WANT TO HEAR WHAT WE GET FROM 821 00:31:20,880 --> 00:31:24,520 THE COMMUNITY, FROM ALL OF YOU, 822 00:31:24,520 --> 00:31:25,280 SO PLEASE SPREAD THE WORD ABOUT 823 00:31:25,280 --> 00:31:25,600 THIS. 824 00:31:25,600 --> 00:31:27,560 WE REALLY HOPE TO GET -- AND THE 825 00:31:27,560 --> 00:31:28,880 RFI IS OPEN RIGHT NOW ON OUR 826 00:31:28,880 --> 00:31:33,160 WEBSITE FOR RESPONSE. 827 00:31:33,160 --> 00:31:43,000 I WANT TO ALSO POINT OUT A NOSI 828 00:31:43,000 --> 00:31:45,720 AIMED AT PROMOTING CHILDREN'S 829 00:31:45,720 --> 00:31:47,160 MENTAL, EMOTIONAL AND BEHAVIORAL 830 00:31:47,160 --> 00:31:49,040 HEALTH IN SCHOOL SETTINGS. 831 00:31:49,040 --> 00:31:52,080 WITH A PARTICULAR FOCUS ON 832 00:31:52,080 --> 00:31:53,160 SCHOOLS THAT SERVE HEALTH 833 00:31:53,160 --> 00:31:54,720 DISPARITY POPULATIONS AND OTHER 834 00:31:54,720 --> 00:31:56,800 VULNERABLE POPULATIONS LIKELY TO 835 00:31:56,800 --> 00:31:57,920 BE UNDERRESOURCED. 836 00:31:57,920 --> 00:31:59,320 WE KNOW THAT MENTAL HEALTH IN 837 00:31:59,320 --> 00:32:03,480 SCHOOLS RIGHT NOW IS REALLY 838 00:32:03,480 --> 00:32:05,360 BECOMING AND ACUTE PROBLEM, 839 00:32:05,360 --> 00:32:08,160 REALLY AN EMERGENCY, SO WE THINK 840 00:32:08,160 --> 00:32:09,960 THIS NOSI IS VERY TIMELY. 841 00:32:09,960 --> 00:32:11,040 ACTUALLY I'M JUST GOING TO 842 00:32:11,040 --> 00:32:12,680 QUICKLY GO BACK TO THE RFI FOR 843 00:32:12,680 --> 00:32:13,560 ONE SECOND. 844 00:32:13,560 --> 00:32:16,200 I FORGOT TO MENTION THAT OUR 845 00:32:16,200 --> 00:32:17,640 ULTIMATE GOAL OF THIS RFI IS NOT 846 00:32:17,640 --> 00:32:21,120 SIMPLY TO IDENTIFY FACTORS, BUT 847 00:32:21,120 --> 00:32:22,760 TO IDENTIFY MEASURES. 848 00:32:22,760 --> 00:32:24,400 SO ONCE WE GET THE INPUT FROM 849 00:32:24,400 --> 00:32:25,920 THE FACTORS, WHAT WE'RE GOING TO 850 00:32:25,920 --> 00:32:27,040 DO IS WE'RE GOING TO BE TAKING 851 00:32:27,040 --> 00:32:28,680 EACH OF THESE FACTORS ONCE WE'VE 852 00:32:28,680 --> 00:32:30,080 DETERMINED THE LIST AND 853 00:32:30,080 --> 00:32:31,520 ASSOCIATE THESE FACTORS WITH A 854 00:32:31,520 --> 00:32:34,000 LIST OF DATA ELEMENTS, 855 00:32:34,000 --> 00:32:34,320 MEASURABLE. 856 00:32:34,320 --> 00:32:38,960 AND THESE COULD BE FROM 857 00:32:38,960 --> 00:32:40,360 QUESTIONNAIRES, FROM WEARABLE 858 00:32:40,360 --> 00:32:41,360 SENSORS, GEOSPATIAL DATA, HEALTH 859 00:32:41,360 --> 00:32:43,000 RECORDS, TO DEFINE EACH OF THESE 860 00:32:43,000 --> 00:32:44,120 FACTORS, AND THEN TO DEVELOP A 861 00:32:44,120 --> 00:32:45,400 SET OF COMMON DATA ELEMENTS THAT 862 00:32:45,400 --> 00:32:49,200 PEOPLE CAN USE TO REALLY IMPROVE 863 00:32:49,200 --> 00:32:52,000 THE RIGOR AND REPRODUCIBILITY 864 00:32:52,000 --> 00:32:53,280 AND GENERALIZABILITY OF THE 865 00:32:53,280 --> 00:32:56,080 STUDIES THAT PEOPLE DO ON WHOLE 866 00:32:56,080 --> 00:33:01,280 PERSON HEALTH. 867 00:33:01,280 --> 00:33:06,480 I WANT TO NOW ALSO POINT OUT 868 00:33:06,480 --> 00:33:09,720 ANOTHER NOSI, NOTICE OF SPECIAL 869 00:33:09,720 --> 00:33:10,840 INTEREST, THAT ENCOURAGES 870 00:33:10,840 --> 00:33:13,680 APPLICATIONS FOR ADMINISTRATIVE 871 00:33:13,680 --> 00:33:15,840 SUPPLEMENTS TO NCCIH SUPPORTED 872 00:33:15,840 --> 00:33:18,160 AWARDS TO SUPPORT COMPLEMENTARY 873 00:33:18,160 --> 00:33:20,360 HEALTH PRACTITIONERS IN AN 874 00:33:20,360 --> 00:33:22,840 INTENSIVE, SUPERVISED RESEARCH 875 00:33:22,840 --> 00:33:24,400 EXPERIENCE THAT WILL LEAD TO A 876 00:33:24,400 --> 00:33:26,800 BETTER UNDERSTANDING OF AND 877 00:33:26,800 --> 00:33:27,640 PRACTICAL EXPERIENCE IN 878 00:33:27,640 --> 00:33:28,840 COMPLEMENTARY AND INTEGRATIVE 879 00:33:28,840 --> 00:33:31,920 HEALTH RESEARCH. 880 00:33:31,920 --> 00:33:33,320 NOW THIS RESEARCH OPPORTUNITY 881 00:33:33,320 --> 00:33:35,200 SUPPORTED UNDER THIS NOSI IS 882 00:33:35,200 --> 00:33:36,400 INTENDED TO PROVIDE A VEHICLE 883 00:33:36,400 --> 00:33:37,960 FOR COMPLEMENTARY HEALTH 884 00:33:37,960 --> 00:33:39,600 PRACTITIONERS TO OBTAIN RESEARCH 885 00:33:39,600 --> 00:33:42,320 SKILLS THAT WILL BENEFIT THE 886 00:33:42,320 --> 00:33:45,080 COMPLEMENTARY HEALTH RESEARCH 887 00:33:45,080 --> 00:33:45,960 COMMUNITY, AS THESE INDIVIDUALS 888 00:33:45,960 --> 00:33:48,000 BRING VERY IMPORTANT IN DEPTH 889 00:33:48,000 --> 00:33:56,200 KNOWLEDGE OF THE DME MEN COY 890 00:33:56,200 --> 00:33:57,840 HEALTH RESEARCH TO THE 891 00:33:57,840 --> 00:33:58,160 ENTERPRISE. 892 00:33:58,160 --> 00:33:59,080 NOW WE ALREADY HAVE RECEIVED A 893 00:33:59,080 --> 00:34:00,720 NUMBER OF APPLICATIONS TO THIS 894 00:34:00,720 --> 00:34:01,840 VERY IMPORTANT RFA ON THE 895 00:34:01,840 --> 00:34:03,560 HEALTHCARE RESEARCH 896 00:34:03,560 --> 00:34:05,200 COLLABORATORY PRAGMATIC AND 897 00:34:05,200 --> 00:34:07,880 IMPLEMENTATION TRIALS OF 898 00:34:07,880 --> 00:34:08,360 EMBEDDED INTERVENTIONS. 899 00:34:08,360 --> 00:34:09,600 BUT I JUST WANT TO POINT OUT 900 00:34:09,600 --> 00:34:11,680 THAT THERE'S ANOTHER RECEIPT 901 00:34:11,680 --> 00:34:15,520 DATE ON JUNE 18TH, SO THERE'S 902 00:34:15,520 --> 00:34:19,440 STILL TIME TO SUBMIT APPLICATION 903 00:34:19,440 --> 00:34:21,760 IS FOR THIS RFA. 904 00:34:21,760 --> 00:34:26,120 NEXT, THIS IS AN OPPORTUNITY FOR 905 00:34:26,120 --> 00:34:29,200 EXISTING T32 TRAINING PROGRAMS 906 00:34:29,200 --> 00:34:30,320 TO APPLY FOR ADMINISTRATIVE 907 00:34:30,320 --> 00:34:31,600 SUPPLEMENT TO SUPPORT ADDITIONAL 908 00:34:31,600 --> 00:34:34,080 TRAINING SLOTS FOR PRE-DOCTORAL 909 00:34:34,080 --> 00:34:35,640 AND POST-DOCTORAL CANDIDATES 910 00:34:35,640 --> 00:34:37,160 FROM DIVERSE BACKGROUNDS, 911 00:34:37,160 --> 00:34:38,160 INCLUDING THOSE FROM GROUPS THAT 912 00:34:38,160 --> 00:34:39,800 ARE UNDERREPRESENTED IN THE 913 00:34:39,800 --> 00:34:41,080 BIOMEDICAL, CLINICAL, BEHAVIORAL 914 00:34:41,080 --> 00:34:44,120 AND SOCIAL SCIENCES. 915 00:34:44,120 --> 00:34:45,160 AND THE NEXT RECEIPT DATE FOR 916 00:34:45,160 --> 00:34:53,720 THIS IS JULY 2ND. 917 00:34:53,720 --> 00:34:59,720 ALSO HERE'S AN OPPORTUNITY FOR 918 00:34:59,720 --> 00:35:04,080 ADDITIONAL T32 -- I JUST SAID 919 00:35:04,080 --> 00:35:04,320 THAT. 920 00:35:04,320 --> 00:35:06,840 DID I DUPLICATE THIS SLIDE? 921 00:35:06,840 --> 00:35:07,280 YEAH. 922 00:35:07,280 --> 00:35:08,840 SORRY. 923 00:35:08,840 --> 00:35:12,080 NOW I WILL MENTION A FEW UPDATES 924 00:35:12,080 --> 00:35:13,640 REGARDING THE HEAL INITIATIVE, 925 00:35:13,640 --> 00:35:16,040 OR HEALTH ADDICTION -- TO END 926 00:35:16,040 --> 00:35:18,560 ADDICTION LONG TERM. 927 00:35:18,560 --> 00:35:21,400 NOW, AS I MENTIONED IN PREVIOUS 928 00:35:21,400 --> 00:35:25,720 REPORTS, WE HAVE OUR SICKLE CELL 929 00:35:25,720 --> 00:35:26,880 DISEASE AND PAIN INITIATIVE THAT 930 00:35:26,880 --> 00:35:28,280 IS PART OF THE HEAL INITIATIVE, 931 00:35:28,280 --> 00:35:29,560 THIS IS FUNDED BY THE HEAL 932 00:35:29,560 --> 00:35:29,960 INITIATIVE. 933 00:35:29,960 --> 00:35:32,040 WE HAD A FANTASTIC TURNOUT AT 934 00:35:32,040 --> 00:35:34,960 OUR WORKSHOP LAST JULY WHICH 935 00:35:34,960 --> 00:35:38,760 RESULTED IN A REQUEST FOR 936 00:35:38,760 --> 00:35:40,000 APPLICATIONS, AND WE HAVE 937 00:35:40,000 --> 00:35:40,960 RECEIVED APPLICATIONS, THE 938 00:35:40,960 --> 00:35:42,600 RECEIPT DATES ARE NOW CLOSED AND 939 00:35:42,600 --> 00:35:44,120 THESE APPLICATIONS ARE UNDER 940 00:35:44,120 --> 00:35:45,320 REVIEW AND WE LOOK FORWARD TO 941 00:35:45,320 --> 00:35:47,000 GIVE YOU AN UPDATE ON THIS 942 00:35:47,000 --> 00:35:50,280 LATER, AT A LATER DATE. 943 00:35:50,280 --> 00:35:51,800 I ALSO WANT TO MENTION THE 944 00:35:51,800 --> 00:35:53,120 MYOFASCIAL PAIN INITIATIVE, ALSO 945 00:35:53,120 --> 00:35:55,440 FUNDED BY THE HEAL INITIATIVE TO 946 00:35:55,440 --> 00:35:58,160 DEVELOP QUANTITATIVE IMAGING 947 00:35:58,160 --> 00:36:01,240 BIOMARKERS OF BIOFACIAL TISSUES, 948 00:36:01,240 --> 00:36:03,960 PREDICT OUTCOMES FOR A VARIETY 949 00:36:03,960 --> 00:36:05,800 OF PAIN MANAGEMENT. 950 00:36:05,800 --> 00:36:07,360 APPLICATIONS AGAIN ARE UNDER 951 00:36:07,360 --> 00:36:09,640 REVIEW AND WE WILL GIVE YOU SOME 952 00:36:09,640 --> 00:36:10,280 UPDATES ON THESE. 953 00:36:10,280 --> 00:36:12,720 I WANT TO ALSO MENTION THAT WE 954 00:36:12,720 --> 00:36:14,680 CONTINUE TO BE INTERESTED FOR 955 00:36:14,680 --> 00:36:17,160 BOTH THE MYOFASCIAL PAIN AND THE 956 00:36:17,160 --> 00:36:18,720 SICKLE CELL PAIN. 957 00:36:18,720 --> 00:36:19,920 WE CONTINUE TO BE INTERESTED IN 958 00:36:19,920 --> 00:36:22,480 THESE TOPICS SO WATCH OUT FOR 959 00:36:22,480 --> 00:36:24,080 POSSIBLE ADDITIONAL RECEIPT 960 00:36:24,080 --> 00:36:29,280 DATES ON THESE INITIATIVES. 961 00:36:29,280 --> 00:36:31,000 HERE IS ANOTHER INITIATIVE 962 00:36:31,000 --> 00:36:35,720 CURRENTLY UNDER REVIEW, 963 00:36:35,720 --> 00:36:40,360 RESTORING JOINT FUNCTION THAT 964 00:36:40,360 --> 00:36:43,600 REFLECTS A VERY IMPORTANT 965 00:36:43,600 --> 00:36:44,880 COLLABORATION BETWEEN THE 966 00:36:44,880 --> 00:36:46,240 NATIONAL INSTITUTES OF ARTHRITIS 967 00:36:46,240 --> 00:36:48,440 AND MUSCULOSKELETAL DISEASES AND 968 00:36:48,440 --> 00:36:52,720 SKIN DISEASES, NCCIH, NINDS, 969 00:36:52,720 --> 00:36:55,000 NEUROLOGICAL DISEASE AND STROKE, 970 00:36:55,000 --> 00:36:57,080 NIDCR, DENTAL AND CRANIOFACIAL 971 00:36:57,080 --> 00:37:00,360 RESEARCH, NIBIB, BIOMEDICAL 972 00:37:00,360 --> 00:37:01,480 ENGINEERING BIOIMAGING, AND 973 00:37:01,480 --> 00:37:02,680 NATIONAL INSTITUTE ON AGING. 974 00:37:02,680 --> 00:37:06,760 AND THE GOAL IS TO DEFINE -- OF 975 00:37:06,760 --> 00:37:10,880 THIS PARTICULAR INITIATIVE IS TO 976 00:37:10,880 --> 00:37:12,200 DEFINE THE INNERVATION OF THE 977 00:37:12,200 --> 00:37:13,840 DIFFERENT ARTICULAR AND 978 00:37:13,840 --> 00:37:15,280 PERIARTICULAR TISSUES THAT 979 00:37:15,280 --> 00:37:17,800 COLLECTIVELY FORM THE JOINT, 980 00:37:17,800 --> 00:37:19,440 INCLUDING BONE, CARTILAGE, 981 00:37:19,440 --> 00:37:21,760 SYNOVIUM, JOINT CAPSULES, 982 00:37:21,760 --> 00:37:22,720 LIGAMENTS, TENDONS, FASCIA, 983 00:37:22,720 --> 00:37:23,840 MUSCLE, ET CETERA. 984 00:37:23,840 --> 00:37:26,000 THESE COMPONENTS, AS WE TALKED 985 00:37:26,000 --> 00:37:29,000 ABOUT THIS AT A PREVIOUS COUNCIL 986 00:37:29,000 --> 00:37:30,080 DISCUSSIONS, VERY IMPORTANT TO 987 00:37:30,080 --> 00:37:33,040 THINK ABOUT A WHOLE JOINT 988 00:37:33,040 --> 00:37:36,840 APPROACH, AND WE WILL BE REALLY 989 00:37:36,840 --> 00:37:38,080 LOOKING AT USING THESE AS A 990 00:37:38,080 --> 00:37:39,160 PLATFORM FOR LOOKING AT 991 00:37:39,160 --> 00:37:40,800 PREVENTIVE STRATEGIES TO PREVENT 992 00:37:40,800 --> 00:37:43,440 THE DEVELOPMENT OF JOINT PAIN 993 00:37:43,440 --> 00:37:46,960 AND DYSFUNCTION. 994 00:37:46,960 --> 00:37:48,480 SO AGAIN, WE HAD A NUMBER OF 995 00:37:48,480 --> 00:37:49,480 APPLICATIONS FOR THESE AND 996 00:37:49,480 --> 00:37:50,120 THEY'RE CURRENTLY BEING 997 00:37:50,120 --> 00:37:55,160 REVIEWED. 998 00:37:55,160 --> 00:38:01,720 PAST ACTIVITIES AS ACTIV. 999 00:38:01,720 --> 00:38:03,560 ARE THEY CONVENED THE THIRD 1000 00:38:03,560 --> 00:38:09,040 ANNUAL MEETING, FEDERAL 1001 00:38:09,040 --> 00:38:11,040 OFFICIALS AND OTHER STAKEHOLDERS 1002 00:38:11,040 --> 00:38:12,640 ACROSS THE COUNTRY TO IDENTIFY 1003 00:38:12,640 --> 00:38:14,000 OPPORTUNITIES TO ADVANCE THE 1004 00:38:14,000 --> 00:38:15,560 GOALS OF THE INITIATIVE. 1005 00:38:15,560 --> 00:38:16,840 AND A RECORDING OF THIS EVENT 1006 00:38:16,840 --> 00:38:18,720 CAN BE FOUND ON THE NIH 1007 00:38:18,720 --> 00:38:23,080 VIDEOCAST WEBSITE. 1008 00:38:23,080 --> 00:38:26,320 NOW, THIS IS ANOTHER IMPORTANT 1009 00:38:26,320 --> 00:38:30,200 PAST EVENT, INTERNATIONALLY 1010 00:38:30,200 --> 00:38:31,240 INTERDISCIPLINARY WORKSHOP 1011 00:38:31,240 --> 00:38:32,640 FOCUSED ON THE THEME OF CREATIVE 1012 00:38:32,640 --> 00:38:33,160 MOVEMENT AND THE BRAIN. 1013 00:38:33,160 --> 00:38:35,680 IT WAS A WONDERFUL SUCCESS. 1014 00:38:35,680 --> 00:38:37,520 THIS IN-PERSON WORKSHOP TOOK 1015 00:38:37,520 --> 00:38:39,120 PLACE AT THE WOLF TRAP NATIONAL 1016 00:38:39,120 --> 00:38:40,400 PARK FOR THE PERFORMING ARTS AND 1017 00:38:40,400 --> 00:38:41,720 THE PLANNING COMMITTEE INVITED 1018 00:38:41,720 --> 00:38:43,360 AN EXCEPTIONALLY WIDE RANGE OF 1019 00:38:43,360 --> 00:38:45,000 SCIENTIST, ENGINEERS, CLINICIANS 1020 00:38:45,000 --> 00:38:46,400 TO EXCHANGE IDEAS AND TO 1021 00:38:46,400 --> 00:38:47,120 INTEGRATE KNOWLEDGE AND 1022 00:38:47,120 --> 00:38:48,520 EXPERIENCE AMONG CREATIVE 1023 00:38:48,520 --> 00:38:50,040 MOVEMENT PROFESSIONALS AND OTHER 1024 00:38:50,040 --> 00:38:51,240 PERFORMING ARTISTS. 1025 00:38:51,240 --> 00:38:54,640 AND THE PRIMARY GOAL OF THE 1026 00:38:54,640 --> 00:38:56,040 EVENT -- GOALS WERE TO ENCOURAGE 1027 00:38:56,040 --> 00:38:57,040 ALL PARTICIPANTS TO REACH BEYOND 1028 00:38:57,040 --> 00:38:58,880 THE CONFINES OF THEIR EXPERTISE 1029 00:38:58,880 --> 00:39:00,000 TO EXPLORE THE SCIENCE OF 1030 00:39:00,000 --> 00:39:02,960 LEARNING TO MOVE. 1031 00:39:02,960 --> 00:39:04,720 HOW THE CREATIVE PROCESS HAD 1032 00:39:04,720 --> 00:39:06,880 MANIFESTED IN THE BRAIN AND HOW 1033 00:39:06,880 --> 00:39:08,680 IT CAN BE HARNESSED TO ENHANCE 1034 00:39:08,680 --> 00:39:09,240 HEALTH AND QUALITY OF LIFE. 1035 00:39:09,240 --> 00:39:13,680 SO VERY, VERY EXCITING. 1036 00:39:13,680 --> 00:39:15,880 THE NCCIH HOT TOPICS WEBINAR 1037 00:39:15,880 --> 00:39:20,120 RECENTLY FEATURED A CONVERSATION 1038 00:39:20,120 --> 00:39:21,000 BETWEEN DR. EMILY EDWARDS, 1039 00:39:21,000 --> 00:39:22,560 MYSELF AND TWO OUTSTANDING 1040 00:39:22,560 --> 00:39:25,200 RESEARCHERS FROM THE UNIVERSITY 1041 00:39:25,200 --> 00:39:26,480 OF MINNESOTA. 1042 00:39:26,480 --> 00:39:29,000 WE HAD A VERY INFORMATIVE 1043 00:39:29,000 --> 00:39:29,640 DISCUSSION ON THE INTERSECTION 1044 00:39:29,640 --> 00:39:32,960 OF RESEARCH ON STRUCTURAL RACISM 1045 00:39:32,960 --> 00:39:36,080 AND DISCRIMINATION AND WHOLE 1046 00:39:36,080 --> 00:39:37,160 PERSON HEALTH. 1047 00:39:37,160 --> 00:39:38,520 THIS WAS VERY WELL ATTENDED. 1048 00:39:38,520 --> 00:39:43,880 WE HAD 549 ATTENDEES AND A 1049 00:39:43,880 --> 00:39:45,480 RECORDING CAN BE FOUND ON THE 1050 00:39:45,480 --> 00:39:49,160 NIH VIDEOCAST SITE. 1051 00:39:49,160 --> 00:39:50,720 NOW WE ALSO HAD A TWO-DAY 1052 00:39:50,720 --> 00:39:52,440 STEERING COMMITTEE MEETING THAT 1053 00:39:52,440 --> 00:39:55,160 CELEBRATED THE 10 YEARS OF THE 1054 00:39:55,160 --> 00:39:57,040 COLLABORATORY HEALTHCARE -- 1055 00:39:57,040 --> 00:39:58,240 PRAGMATIC TRIALS COLLABORATORY 1056 00:39:58,240 --> 00:39:59,360 WHICH HAS RECENTLY BEEN 1057 00:39:59,360 --> 00:40:00,560 REBRANDED. 1058 00:40:00,560 --> 00:40:02,280 THIS IS THE PREVIOUS HEALTHCARE 1059 00:40:02,280 --> 00:40:03,520 SYSTEMS RESEARCH COLLABORATORY 1060 00:40:03,520 --> 00:40:05,360 WHICH NOW HAS A NEW NAME. 1061 00:40:05,360 --> 00:40:07,560 AND THE DISCUSSIONS OF THE 1062 00:40:07,560 --> 00:40:08,760 EVOLUTION AND CURRENT LANDSCAPE 1063 00:40:08,760 --> 00:40:11,480 OF EMBEDDED PRAGMATIC CLINICAL 1064 00:40:11,480 --> 00:40:12,680 TRIALS SHARED THOUGHTS ON 1065 00:40:12,680 --> 00:40:15,320 PRIORITIES FOR THE FUTURES OF 1066 00:40:15,320 --> 00:40:15,960 THESE CLINICAL TRIALS INCLUDING 1067 00:40:15,960 --> 00:40:18,520 HOW TO BETTER SERVE DIVERSE 1068 00:40:18,520 --> 00:40:19,800 POPULATIONS, AND HEAR UPDATES ON 1069 00:40:19,800 --> 00:40:21,200 PROGRESS AND TRANSITION PLANS 1070 00:40:21,200 --> 00:40:23,320 FROM THE UG3 DEMONSTRATION 1071 00:40:23,320 --> 00:40:23,880 PROJECTS. 1072 00:40:23,880 --> 00:40:25,600 IT ALSO FOCUSES ON CHALLENGES 1073 00:40:25,600 --> 00:40:30,200 AND LE SOBS LESSONS LEARNEDE 1074 00:40:30,200 --> 00:40:30,840 DEMONSTRATION PRACTICE AS WELL 1075 00:40:30,840 --> 00:40:33,720 AS THE LATEST BIOETHICS 1076 00:40:33,720 --> 00:40:36,120 ACTIVITIES OF THE NIH 1077 00:40:36,120 --> 00:40:38,640 COLLABORATORY. 1078 00:40:38,640 --> 00:40:42,040 DR. CHRISTOPHER MCCURDY SLIVERED 1079 00:40:42,040 --> 00:40:43,160 AN EXCELLENT PRESENTATION ABOUT 1080 00:40:43,160 --> 00:40:45,040 THE CONTROVERSIAL KRATOM ONCE 1081 00:40:45,040 --> 00:40:46,240 AGAIN IN THE CONTEXT OF THE 1082 00:40:46,240 --> 00:40:47,520 OPIOID CRISIS EVENT. 1083 00:40:47,520 --> 00:40:49,600 HAD A GREAT TURNOUT WITH 1084 00:40:49,600 --> 00:40:53,440 864 TOTAL VIEWS, BOTH LIVE AND 1085 00:40:53,440 --> 00:40:57,520 ON DEMAND. 1086 00:40:57,520 --> 00:40:59,800 AND ANOTHER SUCCESSFUL PAST 1087 00:40:59,800 --> 00:41:03,320 EVENT, THE PRECISIONS PROBIOTICS 1088 00:41:03,320 --> 00:41:04,920 WORKSHOP THAT IDENTIFIES 1089 00:41:04,920 --> 00:41:06,680 KNOWLEDGE GAPS FROM CURRENT 1090 00:41:06,680 --> 00:41:08,360 METHOD OLS AND CHALLENGES IN 1091 00:41:08,360 --> 00:41:10,000 PROBIOTIC RESEARCH, AS WELL AS 1092 00:41:10,000 --> 00:41:10,600 ROAD MAPPING FUTURE DIRECTIONS 1093 00:41:10,600 --> 00:41:14,040 OF THE PRECISION PROBIOTIC 1094 00:41:14,040 --> 00:41:14,360 THERAPIES. 1095 00:41:14,360 --> 00:41:16,560 THERE WERE 11 PARTICIPATING 1096 00:41:16,560 --> 00:41:17,760 INSTITUTES AND CENTERS. 1097 00:41:17,760 --> 00:41:22,480 NCATS, NCCIH, NCI, NHLBI, NIA, 1098 00:41:22,480 --> 00:41:27,160 NIAAA, NIAID, NICHG, ODS AND 1099 00:41:27,160 --> 00:41:29,560 ONR, SO YOU CAN SEE IT WAS A 1100 00:41:29,560 --> 00:41:31,440 VERY, VERY BROAD AND TRANS-NIH 1101 00:41:31,440 --> 00:41:33,600 INTEREST IN THIS. 1102 00:41:33,600 --> 00:41:36,040 OUTSTANDING VIEWERSHIP. 1103 00:41:36,040 --> 00:41:42,120 2,118 LIVE VIEWERS ON DAY ONE 1104 00:41:42,120 --> 00:41:44,080 AND 1500 ON DAY TWO. 1105 00:41:44,080 --> 00:41:45,560 NOW SOME UPCOMING ACTIVITIES AND 1106 00:41:45,560 --> 00:41:46,160 EVENTS. 1107 00:41:46,160 --> 00:41:47,840 PLEASE SAVE THE DATE FOR MAY 1108 00:41:47,840 --> 00:41:50,680 18TH. 1109 00:41:50,680 --> 00:41:53,000 DR. MICHELLE MARTINS IMLS TALK, 1110 00:41:53,000 --> 00:41:54,280 INTEGRATIVE MEDICINE LECTURE 1111 00:41:54,280 --> 00:41:56,080 SERIES ENTITLED "WELL-BEING AND 1112 00:41:56,080 --> 00:41:57,080 ECONOMIC BURDEN OF DISEASE." 1113 00:41:57,080 --> 00:41:59,440 WHAT ARE WE LEARNING FROM CANCER 1114 00:41:59,440 --> 00:42:02,320 SURVIVORS? 1115 00:42:02,320 --> 00:42:06,160 AND ONCE AGAIN, NCCIH WILL HAVE 1116 00:42:06,160 --> 00:42:09,680 A SUBSTANTIAL PRESENCE AT THE 1117 00:42:09,680 --> 00:42:11,600 ANNUAL INTEGRATIVE -- 1118 00:42:11,600 --> 00:42:12,520 INTERNATIONAL CONSORTIUM FOR 1119 00:42:12,520 --> 00:42:15,120 INTEGRATIVE MEDICINE AND HEALTH 1120 00:42:15,120 --> 00:42:18,400 MEETING IN PHOENIX, ARIZONA. 1121 00:42:18,400 --> 00:42:19,040 IN JUST 10 DAYS. 1122 00:42:19,040 --> 00:42:20,720 LEADING A VARIETY OF WORKSHOPS 1123 00:42:20,720 --> 00:42:24,560 AND SYMPOSIA. 1124 00:42:24,560 --> 00:42:25,960 AND I'VE OUTLINED SOME OF THESE 1125 00:42:25,960 --> 00:42:27,640 AT OUR LAST COUNCIL MEETING, AND 1126 00:42:27,640 --> 00:42:28,840 I WILL HAVE THE PLEASURE OF 1127 00:42:28,840 --> 00:42:30,560 HAVING A CONVERSATION WITH 1128 00:42:30,560 --> 00:42:32,640 DR. SUZANNE SIMMARD, PROFESSOR 1129 00:42:32,640 --> 00:42:34,600 OF FOREST ECOLOGY AT THE 1130 00:42:34,600 --> 00:42:35,440 UNIVERSITY OF BRITISH COLUMBIA 1131 00:42:35,440 --> 00:42:38,520 AND THE AUTHOR OF "FINDING THE 1132 00:42:38,520 --> 00:42:40,120 MOTHER TREE" BOOK. 1133 00:42:40,120 --> 00:42:41,080 WONDERFUL BOOK. 1134 00:42:41,080 --> 00:42:43,160 SHE'S A PIONEER IN PLANT 1135 00:42:43,160 --> 00:42:44,000 COMMUNICATION AND KNOWN FOR HER 1136 00:42:44,000 --> 00:42:45,680 RESEARCH ON HOW TREES INTERACT. 1137 00:42:45,680 --> 00:42:47,000 SO REALLY LOOKING FORWARD TO 1138 00:42:47,000 --> 00:42:52,680 THIS CONVERSATION WITH HER. 1139 00:42:52,680 --> 00:42:55,320 AND MARINE JOYCE US FOR OUR 17TH 1140 00:42:55,320 --> 00:42:57,960 ANNUAL PAIN CONSORTIUM SYMPOSIUM 1141 00:42:57,960 --> 00:42:59,120 FEATURING NIH SUPPORTED 1142 00:42:59,120 --> 00:43:00,560 RESEARCHERS WHOSE WORK HAS MADE 1143 00:43:00,560 --> 00:43:01,880 AN IMPORTANT CONTRIBUTION TO 1144 00:43:01,880 --> 00:43:02,960 PAIN RESEARCH. 1145 00:43:02,960 --> 00:43:06,800 AND I'M PLEASED TO SAY THAT THIS 1146 00:43:06,800 --> 00:43:08,040 YEAR'S THEME IS PAIN MANAGEMENT 1147 00:43:08,040 --> 00:43:10,640 THROUGH THE LENS OF WHOLE PERSON 1148 00:43:10,640 --> 00:43:10,880 HEALTH. 1149 00:43:10,880 --> 00:43:12,120 AND KEYNOTE SPEAKERS ARE GOING 1150 00:43:12,120 --> 00:43:16,480 TO BE DR. TRACY GAUDET AND 1151 00:43:16,480 --> 00:43:20,520 DR. RUTH WOLEVER. 1152 00:43:20,520 --> 00:43:22,720 AND IN ADDITION TO SPEAKERS AND 1153 00:43:22,720 --> 00:43:23,880 PANEL SESSIONS, THERE IS A 1154 00:43:23,880 --> 00:43:25,640 POSTER SESSION FEATURING EARLY 1155 00:43:25,640 --> 00:43:26,960 CAREER INVESTIGATORS. 1156 00:43:26,960 --> 00:43:28,960 AND RESEARCHERS WITH THE BEST 1157 00:43:28,960 --> 00:43:31,400 ABSTRACTS ARE SELECTED TO GIVE 1158 00:43:31,400 --> 00:43:32,680 ORAL PRESENTATIONS, AND THERE 1159 00:43:32,680 --> 00:43:37,280 WILL BE THE AWARD FOR BEST 1160 00:43:37,280 --> 00:43:38,400 POSTER AWARDED. 1161 00:43:38,400 --> 00:43:40,360 AND ALSO PLEASE SAVE THE DATE 1162 00:43:40,360 --> 00:43:48,440 FOR JUNE 23RD FOR A TALK 1163 00:43:48,440 --> 00:43:49,760 ENTITLED ADVANCING RESEARCH ON 1164 00:43:49,760 --> 00:43:50,760 EMOTIONAL WELL-BEING AND 1165 00:43:50,760 --> 00:43:55,160 REGULATION OF EATING BY 1166 00:43:55,160 --> 00:43:56,440 DR. ELISSA EPEL. 1167 00:43:56,440 --> 00:43:57,840 FINALLY ON SEPTEMBER 29TH, WE 1168 00:43:57,840 --> 00:43:59,640 WILL BE HOLDING THE INAUGURAL 1169 00:43:59,640 --> 00:44:00,960 ANNUAL INVESTIGATOR MEETING OF 1170 00:44:00,960 --> 00:44:02,240 THE NIH BLUEPRINT FOR 1171 00:44:02,240 --> 00:44:05,120 NEUROSCIENCE RESEARCH ON 1172 00:44:05,120 --> 00:44:08,840 INTEROCEPTION THAT WILL FOCUS ON 1173 00:44:08,840 --> 00:44:09,400 FUNCTIONING NEURAL CIRCUITS. 1174 00:44:09,400 --> 00:44:11,560 SO IF YOU RECALL, THIS WAS AN 1175 00:44:11,560 --> 00:44:12,560 INITIATIVE THAT WAS FUNDED 1176 00:44:12,560 --> 00:44:15,520 THROUGH THE NEUROSCIENCE 1177 00:44:15,520 --> 00:44:18,120 BLUEPRINT, AND IT WILL BE VERY, 1178 00:44:18,120 --> 00:44:20,120 VERY FASCINATING TO SEEK UPDATES 1179 00:44:20,120 --> 00:44:21,400 FROM THESE INVESTIGATORS ON HOW 1180 00:44:21,400 --> 00:44:23,800 THINGS ARE GOING. 1181 00:44:23,800 --> 00:44:26,240 AND I FINALLY WANT TO POINT OUT 1182 00:44:26,240 --> 00:44:29,400 OUR NEXT MEETING, SEPTEMBER 9TH 1183 00:44:29,400 --> 00:44:33,440 OF OUR ADVISORY COUNCIL. 1184 00:44:33,440 --> 00:44:38,920 AND I WANT TO ALSO JUST MENTION 1185 00:44:38,920 --> 00:44:40,560 THAT WE ARE DOING A LITTLE BIT 1186 00:44:40,560 --> 00:44:42,960 OF AN EXPERIMENT TODAY FOR THIS 1187 00:44:42,960 --> 00:44:44,960 COUNCIL BECAUSE WE ARE DOING A 1188 00:44:44,960 --> 00:44:47,360 HYBRID -- A LITTLE MINI HYBRID 1189 00:44:47,360 --> 00:44:52,720 MEETING, AS YOU CAN SEE, SOME OF 1190 00:44:52,720 --> 00:44:54,160 US, THE NCCIH STAFF IS IN THE 1191 00:44:54,160 --> 00:44:54,560 ROOM. 1192 00:44:54,560 --> 00:44:56,560 MOST OF THEM -- MOST OF THE 1193 00:44:56,560 --> 00:45:00,040 STAFF IS VIRTUAL, AND SO ARE THE 1194 00:45:00,040 --> 00:45:00,600 COUNCILMEMBERS. 1195 00:45:00,600 --> 00:45:01,800 BUT WHAT WE WANT TO KNOW AND WE 1196 00:45:01,800 --> 00:45:05,080 WOULD LIKE TO HEAR FROM OUR 1197 00:45:05,080 --> 00:45:06,400 COUNCILMEMBERS IS HOW WOULD YOU 1198 00:45:06,400 --> 00:45:10,360 ALL FEEL ABOUT EXPANDING THIS IN 1199 00:45:10,360 --> 00:45:11,760 SEPTEMBER AS LONG AS, YOU KNOW, 1200 00:45:11,760 --> 00:45:15,160 COVID STATISTICS PERMIT, WE 1201 00:45:15,160 --> 00:45:17,680 WOULD KIND OF OPEN THIS UP AND 1202 00:45:17,680 --> 00:45:21,120 REALLY EXTEND THIS TO BE A MORE 1203 00:45:21,120 --> 00:45:22,320 FULLY HYBRID MEETING WHERE 1204 00:45:22,320 --> 00:45:22,960 COUNCILMEMBERS WOULD BE INVITED 1205 00:45:22,960 --> 00:45:24,280 TO COME AND PARTICIPATE IN 1206 00:45:24,280 --> 00:45:25,600 PERSON AND HOPEFULLY WE CAN ALSO 1207 00:45:25,600 --> 00:45:27,680 HAVE A SOCIAL EVENT AT THIS 1208 00:45:27,680 --> 00:45:28,720 MEETING, WHICH WE HAVEN'T HAD 1209 00:45:28,720 --> 00:45:32,400 NOW FOR TWO YEARS. 1210 00:45:32,400 --> 00:45:37,320 AND I WOULD BE CURIOUS TO 1211 00:45:37,320 --> 00:45:38,560 HEAR -- I SEE SOMEBODY CHIMING 1212 00:45:38,560 --> 00:45:39,440 IN IN THE CHAT. 1213 00:45:39,440 --> 00:45:40,640 BUT WE'D LOVE TO HEAR WHAT ARE 1214 00:45:40,640 --> 00:45:42,800 YOUR THOUGHTS ON THIS. 1215 00:45:42,800 --> 00:45:43,880 SO AS WELL AS ANY OTHER 1216 00:45:43,880 --> 00:45:45,880 MATERIALS THAT I PRESENTED. 1217 00:45:45,880 --> 00:45:51,480 SO I'M GOING TO STOP SHARING. 1218 00:45:51,480 --> 00:45:55,400 YOU CAN REMOVE THE SLIDES AND 1219 00:45:55,400 --> 00:45:58,240 WE'D LOVE TO HEAR COMMENTS FROM 1220 00:45:58,240 --> 00:46:01,440 COUNCIL ON ANY OF THESE TOPICS. 1221 00:46:01,440 --> 00:46:03,320 >> SO AGAIN FOR COUNCILMEMBERS, 1222 00:46:03,320 --> 00:46:04,920 IF YOU'LL RAISE YOUR DIGITAL 1223 00:46:04,920 --> 00:46:09,400 HAND OR WAVE AT US VIA VIDEO, 1224 00:46:09,400 --> 00:46:10,720 WE'LL CALL ON YOU IN ORDER THAT 1225 00:46:10,720 --> 00:46:19,480 YOU SO INDICATE. 1226 00:46:19,480 --> 00:46:23,960 AND AS YOU GATHER YOUR 1227 00:46:23,960 --> 00:46:24,280 THOUGHTS -- 1228 00:46:24,280 --> 00:46:25,600 >> YEAH, AS YOU GATHER YOUR 1229 00:46:25,600 --> 00:46:27,040 THOUGHTS, I'M JUST GETTING A 1230 00:46:27,040 --> 00:46:28,360 PING FROM OUR DIRECTOR OF OFFICE 1231 00:46:28,360 --> 00:46:30,640 AND POLICY PLANNING EVALUATION. 1232 00:46:30,640 --> 00:46:32,080 I WANT TO JUST MENTION ALSO THAT 1233 00:46:32,080 --> 00:46:38,320 I RECENTLY HAD A CONGRESS FLAL 1234 00:46:38,320 --> 00:46:40,640 HEARING, BRIEFING, WITH TWO 1235 00:46:40,640 --> 00:46:45,640 CONGRESS MEMBERS, CONGRESSWOMAN 1236 00:46:45,640 --> 00:46:49,240 JACKIE WILORSKY AND 1237 00:46:49,240 --> 00:46:50,880 CONGRESSWOMAN JUDY CHU, WHO ARE 1238 00:46:50,880 --> 00:46:52,280 BOTH CO-CHAIRS OF THE 1239 00:46:52,280 --> 00:46:54,640 INTEGRATIVE HEALTH CAUCUS. 1240 00:46:54,640 --> 00:46:55,840 AND SO IT WAS VERY WELL 1241 00:46:55,840 --> 00:46:56,280 RECEIVED. 1242 00:46:56,280 --> 00:46:59,800 WE TALKED ABOUT WHOLE PERSON 1243 00:46:59,800 --> 00:47:02,200 HEALTH AS WELL AS THE IMPORTANCE 1244 00:47:02,200 --> 00:47:03,320 OF CHRONIC STRESS. 1245 00:47:03,320 --> 00:47:07,680 AND HOW CHRONIC STRESS IS REALLY 1246 00:47:07,680 --> 00:47:10,320 REACHING ALARMING PROPORTIONS, 1247 00:47:10,320 --> 00:47:13,800 ESPECIALLY INCREASINGLY IN THE 1248 00:47:13,800 --> 00:47:15,440 U.S., THERE ARE SOME SURVEYS 1249 00:47:15,440 --> 00:47:20,400 THAT ARE -- QUITE CONCLUSIVELY 1250 00:47:20,400 --> 00:47:21,400 SHOW PEOPLE IN THE UNITED STATES 1251 00:47:21,400 --> 00:47:22,560 HAVE LEVELS OF STRESS THAT ARE 1252 00:47:22,560 --> 00:47:24,080 AMONG THE HIGHEST IN THE WORLD. 1253 00:47:24,080 --> 00:47:28,080 AND WE ALSO HAVE SOME DISTURBING 1254 00:47:28,080 --> 00:47:30,320 HEALTH STATISTICS, THAT OUR LIFE 1255 00:47:30,320 --> 00:47:31,760 EXPECTANCY IS DECREASING, WE 1256 00:47:31,760 --> 00:47:32,720 HAVE A LOT OF PROBLEMS WITH 1257 00:47:32,720 --> 00:47:34,080 DIFFERENT AREAS OF HEALTH THAT 1258 00:47:34,080 --> 00:47:40,080 CAN BE INFLAWNSED BY STRESS, 1259 00:47:40,080 --> 00:47:43,280 INCLUDING OPIOID USAGE, DEATH, 1260 00:47:43,280 --> 00:47:46,640 ADDICTION, PAIN, AND AS WELL AS 1261 00:47:46,640 --> 00:47:49,200 MENTAL HEALTH, BUT ALSO VERY 1262 00:47:49,200 --> 00:47:51,360 IMPORTANTLY, PHYSICAL HEALTH. 1263 00:47:51,360 --> 00:47:55,640 WE HAVE RISING RATES OF 1264 00:47:55,640 --> 00:47:56,960 CARDIOVASCULAR DISEASE, CHRONIC 1265 00:47:56,960 --> 00:48:00,000 OBESITY AND METABOLIC DIABETES, 1266 00:48:00,000 --> 00:48:01,520 TYPE 2 DIABETES THAT CAN -- THAT 1267 00:48:01,520 --> 00:48:03,840 ARE WORSENED, AND HYPERTENSION 1268 00:48:03,840 --> 00:48:04,720 WORSENED BY STRESS. 1269 00:48:04,720 --> 00:48:08,320 AND, OF COURSE, COVID. 1270 00:48:08,320 --> 00:48:10,160 AND WE NE OUR IMMUNE RESPONSES 1271 00:48:10,160 --> 00:48:10,720 ARE INFLUENCED BY STRESS. 1272 00:48:10,720 --> 00:48:12,280 SO THIS IS AN AREA WE FEEL WE 1273 00:48:12,280 --> 00:48:13,520 REALLY WANT TO RAISE AWARENESS 1274 00:48:13,520 --> 00:48:14,760 OF THE IMPORTANCE OF STRESS 1275 00:48:14,760 --> 00:48:17,600 MANAGEMENT, NOT ONLY FOR 1276 00:48:17,600 --> 00:48:19,720 PSYCHOLOGICAL REASONS THEY'RE 1277 00:48:19,720 --> 00:48:21,120 EXTREMELY IMPORTANT BUT FOR 1278 00:48:21,120 --> 00:48:22,760 PHYSIOLOGICAL REASONS AS WELL. 1279 00:48:22,760 --> 00:48:25,040 AND SO WE DISCUSSED THIS AND 1280 00:48:25,040 --> 00:48:26,480 THERE WAS A LOT OF INTEREST IN 1281 00:48:26,480 --> 00:48:32,720 THIS TOPIC. 1282 00:48:32,720 --> 00:48:34,560 SO THANK YOU, MARY BETH, FOR 1283 00:48:34,560 --> 00:48:35,680 REMINDING ME TO MENTION IT. 1284 00:48:35,680 --> 00:48:37,520 >> QUESTIONS, COMMENTS FROM 1285 00:48:37,520 --> 00:48:40,000 COUNCIL? 1286 00:48:40,000 --> 00:48:44,720 >> DR. CECH? 1287 00:48:44,720 --> 00:48:46,520 >> I JUST WANTED TO SAY THANK 1288 00:48:46,520 --> 00:48:47,160 YOU, THAT WAS A REALLY 1289 00:48:47,160 --> 00:48:48,960 INTERESTING AND DIVERSE OVERVIEW 1290 00:48:48,960 --> 00:48:52,120 OF SOME REALLY EXCITING 1291 00:48:52,120 --> 00:48:52,400 INITIATIVES. 1292 00:48:52,400 --> 00:48:55,720 I'M JUST OBSERVING THAT THERE'S 1293 00:48:55,720 --> 00:48:58,600 SUCH A THEME HERE OF 1294 00:48:58,600 --> 00:48:59,560 INTERCONNECTIVITY THAT NCCIH HAS 1295 00:48:59,560 --> 00:49:01,640 REALLY BEEN MAKING AN EFFORT TO 1296 00:49:01,640 --> 00:49:02,840 CONNECT WITH OTHER INSTITUTES 1297 00:49:02,840 --> 00:49:06,360 AND OTHER PROJECTS ACROSS NIH 1298 00:49:06,360 --> 00:49:08,120 REALLY IN A FORWARD-THINKING WAY 1299 00:49:08,120 --> 00:49:09,880 EVEN BEFORE WE WERE MOVING INTO 1300 00:49:09,880 --> 00:49:11,920 THIS SITUATION THAT WE'RE IN 1301 00:49:11,920 --> 00:49:13,120 CURRENTLY WITH SUCH A 1302 00:49:13,120 --> 00:49:14,480 REALIZATION OF HOW ALL THE 1303 00:49:14,480 --> 00:49:17,080 DIFFERENT TYPES OF STRESSORS 1304 00:49:17,080 --> 00:49:19,160 THAT WE'RE HAVING ON OUR LIVES 1305 00:49:19,160 --> 00:49:21,040 ARE REALLY IMPACTING HEALTH IN 1306 00:49:21,040 --> 00:49:22,560 WAYS THAT CANNOT BE ISOLATED TO 1307 00:49:22,560 --> 00:49:24,080 A SINGLE DISEASE. 1308 00:49:24,080 --> 00:49:25,840 AND NCCIH HAS REALLY BEEN A 1309 00:49:25,840 --> 00:49:28,120 LEADER IN THINKING ABOUT WHOLE 1310 00:49:28,120 --> 00:49:29,800 BODY HEALTH AND 1311 00:49:29,800 --> 00:49:30,400 INTERCONNECTIVITY FOR A VERY 1312 00:49:30,400 --> 00:49:31,760 LONG TIME, BUT IT'S EXCITING TO 1313 00:49:31,760 --> 00:49:33,400 SEE SOME OF THIS COMING TO 1314 00:49:33,400 --> 00:49:35,360 FRUITION AND SEE SOME OF THE 1315 00:49:35,360 --> 00:49:38,120 INTEGRATED EFFORTS ACROSS NIH 1316 00:49:38,120 --> 00:49:39,240 AND ALSO THE EFFORTS TO REACH 1317 00:49:39,240 --> 00:49:40,560 OUT TO COMMUNITIES THAT HAVEN'T 1318 00:49:40,560 --> 00:49:42,160 PARTICIPATED IN SOME OF THESE IN 1319 00:49:42,160 --> 00:49:45,800 THE PAST AND REACHING OUT TO 1320 00:49:45,800 --> 00:49:47,120 PEOPLE TO GET THEIR OPINIONS 1321 00:49:47,120 --> 00:49:48,120 ABOUT WHAT ARE THE MOST 1322 00:49:48,120 --> 00:49:49,080 IMPORTANT VARIABLES WE SHOULD BE 1323 00:49:49,080 --> 00:49:49,840 LOOKING AT IN RESEARCH. 1324 00:49:49,840 --> 00:49:52,160 I JUST THINK IT'S REALLY VERY 1325 00:49:52,160 --> 00:49:54,760 CUTTING EDGE AND I JUST WANT TO 1326 00:49:54,760 --> 00:49:55,840 ACKNOWLEDGE ALL OF THE EFFORT OF 1327 00:49:55,840 --> 00:49:58,920 ALL THE PEOPLE WHO'VE 1328 00:49:58,920 --> 00:49:59,880 CONTRIBUTED TO THAT. 1329 00:49:59,880 --> 00:50:01,000 IT'S REALLY EXCITING TO SEE. 1330 00:50:01,000 --> 00:50:02,520 >> WELL, THANK YOU FOR THIS 1331 00:50:02,520 --> 00:50:03,000 COMMENT. 1332 00:50:03,000 --> 00:50:03,960 I REALLY APPRECIATE IT. 1333 00:50:03,960 --> 00:50:05,480 WE ALL DO. 1334 00:50:05,480 --> 00:50:07,640 IT'S VERY INTERESTING AS YOU 1335 00:50:07,640 --> 00:50:11,240 SAID THAT THE INTERCONNECTIVITY 1336 00:50:11,240 --> 00:50:12,680 IS SO IMPORTANT AND SO VITAL TO 1337 00:50:12,680 --> 00:50:17,080 HOW WE THINK, BUT ALSO REACHING 1338 00:50:17,080 --> 00:50:18,400 OUT TO OTHER GROUPS, BY 1339 00:50:18,400 --> 00:50:21,040 NECESSITY, RIGHT, AT NCCIH 1340 00:50:21,040 --> 00:50:22,160 BECAUSE WE HAVE SUCH A SMALL 1341 00:50:22,160 --> 00:50:24,200 BUDGET, WE NEED TO REACH OUT AND 1342 00:50:24,200 --> 00:50:25,400 WE'VE BEEN ACTUALLY VERY 1343 00:50:25,400 --> 00:50:28,680 SUCCESSFUL IN GETTING CO-FUNDING 1344 00:50:28,680 --> 00:50:30,360 PARTICIPATION IN THESE TRANS-NIH 1345 00:50:30,360 --> 00:50:32,000 INITIATIVES WHICH ALLOWS US TO 1346 00:50:32,000 --> 00:50:34,000 AUGMENT THE FUNDS THAT WE HAVE. 1347 00:50:34,000 --> 00:50:35,720 SO, SO FAR, SO GOOD I THINK, 1348 00:50:35,720 --> 00:50:36,160 YES. 1349 00:50:36,160 --> 00:50:40,320 BEN AND THEN JUSTIN AND THEN -- 1350 00:50:40,320 --> 00:50:41,720 >> THANKS, DR. LANGEVIN. 1351 00:50:41,720 --> 00:50:43,040 I JUST HAVE A QUESTION, I GUESS, 1352 00:50:43,040 --> 00:50:44,760 WHICH IS, AS YOU DO THAT 1353 00:50:44,760 --> 00:50:48,080 REACHING OUT ACROSS TO OTHER 1354 00:50:48,080 --> 00:50:51,040 INSTITUTES, HOW DO YOU FIND THE 1355 00:50:51,040 --> 00:50:52,240 RECEPTION TO THIS CONCEPT OF 1356 00:50:52,240 --> 00:50:53,120 WHOLE PERSON HEALTH? 1357 00:50:53,120 --> 00:50:55,720 DO YOU FIND A LOT OF OPENNESS 1358 00:50:55,720 --> 00:50:57,040 AND WILLINGNESS TO GET ON BOARD 1359 00:50:57,040 --> 00:50:58,680 WITH THE INITIATIVES? DO YOU 1360 00:50:58,680 --> 00:51:00,560 FIND STILL A FAIR AMOUNT OF 1361 00:51:00,560 --> 00:51:01,840 SKEPTICISM FROM THE OTHER 1362 00:51:01,840 --> 00:51:02,960 INSTITUTES? 1363 00:51:02,960 --> 00:51:04,800 I'M JUST CURIOUS, YOUR GENERAL 1364 00:51:04,800 --> 00:51:05,320 IMPRESSION ON THAT. 1365 00:51:05,320 --> 00:51:06,560 >> A LOT OF INTEREST. 1366 00:51:06,560 --> 00:51:09,720 AND IN FACT, THE PROOF OF THAT 1367 00:51:09,720 --> 00:51:12,840 WAS THE FANTASTIC COLLABORATIONS 1368 00:51:12,840 --> 00:51:14,320 THAT WE IN OUR WHOLE PERSON 1369 00:51:14,320 --> 00:51:15,080 RESEARCH WORKSHOP. 1370 00:51:15,080 --> 00:51:18,600 THIS WORKSHOP WAS ORGANIZED IN 1371 00:51:18,600 --> 00:51:20,560 COLLABORATION WITH A NUMBER OF 1372 00:51:20,560 --> 00:51:24,080 DIFFERENT INSTITUTES, AND WE HAD 1373 00:51:24,080 --> 00:51:25,800 PROGRAM OFFICERS FROM ALL THESE 1374 00:51:25,800 --> 00:51:27,000 INSTITUTES COME AND HELP US 1375 00:51:27,000 --> 00:51:28,320 SHAPE THE PROGRAM AND 1376 00:51:28,320 --> 00:51:31,280 CONTRIBUTED THEIR INVESTIGATORS 1377 00:51:31,280 --> 00:51:32,680 TO THIS VERY AMAZING WORKSHOP 1378 00:51:32,680 --> 00:51:34,000 THAT OCCURRED. 1379 00:51:34,000 --> 00:51:35,320 SO WE ON PURPOSE WANTED THAT, 1380 00:51:35,320 --> 00:51:36,960 BECAUSE WE WANTED TO HEAR FROM 1381 00:51:36,960 --> 00:51:38,160 OTHER FIELDS THAT ARE ALREADY 1382 00:51:38,160 --> 00:51:41,200 THINKING IN AN INTEGRATIVE 1383 00:51:41,200 --> 00:51:43,000 DIRECTION, WHO ARE ALREADY 1384 00:51:43,000 --> 00:51:46,720 THINKING ACROSS SYSTEMS AND 1385 00:51:46,720 --> 00:51:47,320 ACROSS DOMAINS. 1386 00:51:47,320 --> 00:51:49,040 OF COURSE THE INSTITUTES THAT 1387 00:51:49,040 --> 00:51:51,120 ARE MORE -- ALREADY HAVE, FOR 1388 00:51:51,120 --> 00:51:54,280 EXAMPLE, ENVIRONMENTAL HEALTH, 1389 00:51:54,280 --> 00:51:55,720 NURSING, MINORITY HEALTH, AGING, 1390 00:51:55,720 --> 00:51:57,240 THESE ARE THE INSTITUTES THAT 1391 00:51:57,240 --> 00:51:59,880 ARE WHAT WE CALL 1392 00:51:59,880 --> 00:52:00,520 NON-CATEGORICAL, THOSE ALREADY 1393 00:52:00,520 --> 00:52:02,720 THINK THIS WAY. 1394 00:52:02,720 --> 00:52:04,480 BUT WE ALSO HAD -- WE HAVE A LOT 1395 00:52:04,480 --> 00:52:08,080 OF INTEREST NOW FOR VERY 1396 00:52:08,080 --> 00:52:08,800 IMPORTANTLY THE MUSCULOSKELETAL, 1397 00:52:08,800 --> 00:52:11,680 YOU'RE GOING TO HEAR THIS 1398 00:52:11,680 --> 00:52:16,080 AFTERNOON FROM DR. RENA DSOUZA, 1399 00:52:16,080 --> 00:52:17,600 THEY ARE ALSO REALLY THINKING IN 1400 00:52:17,600 --> 00:52:18,840 AN INTEGRATIVE WAY. 1401 00:52:18,840 --> 00:52:19,600 SHE'S GOING TO BE TALKING ABOUT 1402 00:52:19,600 --> 00:52:21,320 THIS TOO. 1403 00:52:21,320 --> 00:52:22,640 SO THE WORD IS DEFINITELY 1404 00:52:22,640 --> 00:52:23,200 SPREADING. 1405 00:52:23,200 --> 00:52:27,760 IT'S GONE REALLY WELL. 1406 00:52:27,760 --> 00:52:28,280 DR. SONNENBURG, JUSTIN? 1407 00:52:28,280 --> 00:52:32,320 >> HELENE, THANKS FOR THE REALLY 1408 00:52:32,320 --> 00:52:32,720 WONDERFUL OVERVIEW. 1409 00:52:32,720 --> 00:52:36,320 FAST MOVING, THERE'S A TON GOING 1410 00:52:36,320 --> 00:52:37,320 ON. 1411 00:52:37,320 --> 00:52:38,960 I THINK JUST TO KIND OF ECHO 1412 00:52:38,960 --> 00:52:41,160 SOME OF THOSE SENTIMENTS, JUST 1413 00:52:41,160 --> 00:52:42,160 OVER THE PAST FOUR YEARS OF 1414 00:52:42,160 --> 00:52:44,240 BEING ON COUNCIL, SEEING THIS 1415 00:52:44,240 --> 00:52:45,800 DIFFERENT WAY OF THINKING ABOUT 1416 00:52:45,800 --> 00:52:48,840 DOING MEDICINE AND THINKING 1417 00:52:48,840 --> 00:52:50,160 ABOUT HEALTH, TRANSITIONING FROM 1418 00:52:50,160 --> 00:52:52,200 BEING SOMETHING THAT IS, YOU 1419 00:52:52,200 --> 00:52:53,840 KNOW -- I THINK FELT VERY 1420 00:52:53,840 --> 00:52:54,960 FOREIGN, IT FELT LIKE TO A LOT 1421 00:52:54,960 --> 00:52:57,040 OF NIH TO NOW BEING REALLY 1422 00:52:57,040 --> 00:52:58,240 CENTRAL AND BEING AT THE LEADING 1423 00:52:58,240 --> 00:52:59,560 EDGE, I THINK THAT'S SUPER 1424 00:52:59,560 --> 00:53:00,600 EXCITING TO SEE THE INTEGRATION 1425 00:53:00,600 --> 00:53:02,160 WITH ALL THE OTHER INSTITUTES 1426 00:53:02,160 --> 00:53:03,360 AND CENTERS, ALL THE JOINT 1427 00:53:03,360 --> 00:53:06,560 INITIATIVES AND JUST TO 1428 00:53:06,560 --> 00:53:07,200 HIGHLIGHT ONE POINT THAT YOU 1429 00:53:07,200 --> 00:53:08,720 TOUCHED ON, THAT TRANS-NIH 1430 00:53:08,720 --> 00:53:10,320 WORKSHOP ON PROBIOTIC THERAPIES 1431 00:53:10,320 --> 00:53:13,960 THAT I WAS PART OF, I THINK THAT 1432 00:53:13,960 --> 00:53:15,320 WAS JUST A SUPER INSPIRING TWO 1433 00:53:15,320 --> 00:53:16,600 DAYS. 1434 00:53:16,600 --> 00:53:18,120 INCREDIBLE LINEUP OF SPEAKERS, 1435 00:53:18,120 --> 00:53:18,600 INCREDIBLE DISCUSSION. 1436 00:53:18,600 --> 00:53:21,880 THAT FIELD IS CLEARLY GOING IN A 1437 00:53:21,880 --> 00:53:25,440 LOT OF INTERESTING DISCUSSIONS, 1438 00:53:25,440 --> 00:53:27,440 INCORPORATING PROBIOTICS 2.0, 1439 00:53:27,440 --> 00:53:29,200 MICROBES FROM THE GUT AS 1440 00:53:29,200 --> 00:53:31,920 PROBIOTICS AND EVEN ENGINEERED 1441 00:53:31,920 --> 00:53:32,680 MICROBES FROM THE GUT. 1442 00:53:32,680 --> 00:53:35,200 SO I THINK THERE'S JUST SO MANY 1443 00:53:35,200 --> 00:53:36,840 EXCITING THINGS GOING ON THERE. 1444 00:53:36,840 --> 00:53:37,840 AND THEN JUST A FINAL THANK YOU 1445 00:53:37,840 --> 00:53:39,320 TO THE NCCIH STAFF THAT WERE 1446 00:53:39,320 --> 00:53:40,040 INVOLVED IN PULLING THAT OFF. 1447 00:53:40,040 --> 00:53:42,520 IT WAS REALLY JUST A REALLY 1448 00:53:42,520 --> 00:53:45,280 EXCELLENT WORKSHOP AND 1449 00:53:45,280 --> 00:53:45,560 DISCUSSION. 1450 00:53:45,560 --> 00:53:46,360 >> THANK YOU FOR THIS COMMENT. 1451 00:53:46,360 --> 00:53:48,880 I WANT TO SAY ALSO A VERY 1452 00:53:48,880 --> 00:53:49,760 INTERESTING THING. 1453 00:53:49,760 --> 00:53:52,400 A COUPLE YEARS AGO, WE DID A 1454 00:53:52,400 --> 00:53:53,160 PORTFOLIO ANALYSIS AND WE LOOKED 1455 00:53:53,160 --> 00:53:54,680 AT THE KIND OF RESEARCH THAT WE 1456 00:53:54,680 --> 00:53:55,880 WERE ALREADY FUNDING, LIKE IN 1457 00:53:55,880 --> 00:53:59,840 PREVIOUS YEARS, THAT WENT ACROSS 1458 00:53:59,840 --> 00:54:00,040 SYSTEMS. 1459 00:54:00,040 --> 00:54:03,120 AND THE NATURAL PRODUCTS 1460 00:54:03,120 --> 00:54:04,760 PORTFOLIO AND PROBIOTICS AND 1461 00:54:04,760 --> 00:54:06,280 MICROBIOME WAS SOME OF THE MOST 1462 00:54:06,280 --> 00:54:07,280 INTEGRATIVE RESEARCH THAT WE 1463 00:54:07,280 --> 00:54:09,240 WERE ALREADY FUNDING. 1464 00:54:09,240 --> 00:54:10,560 SO IT'S VERY INTERESTING THAT 1465 00:54:10,560 --> 00:54:11,960 THIS FIELD HAS BEEN REALLY 1466 00:54:11,960 --> 00:54:13,080 LEADING THE WAY IN UNDERSTANDING 1467 00:54:13,080 --> 00:54:18,120 HOW THE BODY IS CONNECTED, SO 1468 00:54:18,120 --> 00:54:20,400 IT'S VERY INTERESTING TO SEE 1469 00:54:20,400 --> 00:54:21,080 THAT. 1470 00:54:21,080 --> 00:54:21,360 SO EMILY? 1471 00:54:21,360 --> 00:54:23,160 >> THANK YOU, HELENE. 1472 00:54:23,160 --> 00:54:25,480 IT'S FUNNY, AS WE DO THIS ON A 1473 00:54:25,480 --> 00:54:26,840 DAY-TO-DAY BASIS WITHOUT 1474 00:54:26,840 --> 00:54:28,840 REALIZING HOW MANY ACTIVITIES, 1475 00:54:28,840 --> 00:54:29,720 EXCITING ACTIVITIES THAT WE'RE 1476 00:54:29,720 --> 00:54:30,280 INVOLVED IN. 1477 00:54:30,280 --> 00:54:33,040 SO THANK YOU FOR THIS WONDERFUL 1478 00:54:33,040 --> 00:54:33,320 SUMMARY. 1479 00:54:33,320 --> 00:54:40,000 BUT I WANTED TO JUST HIGHLIGHT 1480 00:54:40,000 --> 00:54:40,880 THE TWO INTEGRATIVE MEDICINE 1481 00:54:40,880 --> 00:54:45,120 SERIES YOU MENTIONED, DR. MARTIN 1482 00:54:45,120 --> 00:54:47,200 AND DR. EPEL, THEY'RE FROM THE 1483 00:54:47,200 --> 00:54:48,120 RESEARCH NETWORKS THAT WERE 1484 00:54:48,120 --> 00:54:50,920 FUNDED IN 2020, AND THAT 1485 00:54:50,920 --> 00:54:54,000 GROUP -- THOSE NETWORKS ARE 1486 00:54:54,000 --> 00:54:55,320 FULLY FUNCTIONING AND REALLY 1487 00:54:55,320 --> 00:54:56,840 MOVING FORWARD, SO I'M REALLY 1488 00:54:56,840 --> 00:54:57,600 HAPPY THAT WE'RE ABOUT TO 1489 00:54:57,600 --> 00:54:59,240 FEATURE THE WORK OF SOME OF THE 1490 00:54:59,240 --> 00:55:01,120 THOSE NETWORKS IN THE NEXT 1491 00:55:01,120 --> 00:55:04,640 COUPLE OF MONTHS. 1492 00:55:04,640 --> 00:55:05,080 THANKS. 1493 00:55:05,080 --> 00:55:07,600 >> THANK YOU, EMMELINE, YES, 1494 00:55:07,600 --> 00:55:08,160 THANK YOU, VERY IMPORTANT. 1495 00:55:08,160 --> 00:55:09,120 THANK YOU FOR MENTIONING THAT. 1496 00:55:09,120 --> 00:55:09,320 KAREN? 1497 00:55:09,320 --> 00:55:11,640 >> I FIND THIS VERY, VERY 1498 00:55:11,640 --> 00:55:12,960 EXCITING. 1499 00:55:12,960 --> 00:55:14,400 ONE OF THE CHALLENGES, THOUGH, 1500 00:55:14,400 --> 00:55:16,120 AS I THINK ABOUT WHAT YOU'VE 1501 00:55:16,120 --> 00:55:20,720 SAID ABOUT STRESS, HAVING REALLY 1502 00:55:20,720 --> 00:55:22,800 RISEN RELATIVELY RAPIDLY DURING 1503 00:55:22,800 --> 00:55:24,320 THE COVID PERIOD, AND JUST 1504 00:55:24,320 --> 00:55:26,880 LOOKING AT WORLD EVENTS, IT 1505 00:55:26,880 --> 00:55:27,960 DOESN'T LOOK LIKE IT'S GOING TO 1506 00:55:27,960 --> 00:55:30,000 COME DOWN ANY TIME SOON, BUT OUR 1507 00:55:30,000 --> 00:55:31,560 TYPICAL, YOU KNOW, IT TAKES 1508 00:55:31,560 --> 00:55:32,440 THREE TO FIVE YEARS TO GET 1509 00:55:32,440 --> 00:55:34,800 RESULTS AND GET THEM OUT AND 1510 00:55:34,800 --> 00:55:36,680 STUFF IS A LITTLE CONCERN, AND 1511 00:55:36,680 --> 00:55:38,320 I'M JUST WONDERING IF THERE'S A 1512 00:55:38,320 --> 00:55:42,160 WAY TO PUT TOGETHER SOMETHING 1513 00:55:42,160 --> 00:55:44,240 FROM ALL OF US WITH MAYBE SOME 1514 00:55:44,240 --> 00:55:45,760 ONLINE INTERVENTIONS AND SOME 1515 00:55:45,760 --> 00:55:46,880 REALLY NOVEL, QUICK, RAPID WAYS 1516 00:55:46,880 --> 00:55:49,600 OF GETTING THINGS OUT AND 1517 00:55:49,600 --> 00:55:51,040 TESTING THEM, MAYBE TESTING 1518 00:55:51,040 --> 00:55:52,240 MULTIPLE THINGS AT ONCE OR 1519 00:55:52,240 --> 00:55:54,520 WHATEVER, TO REALLY OFFER THINGS 1520 00:55:54,520 --> 00:55:58,280 TO PEOPLE SOON. 1521 00:55:58,280 --> 00:55:59,240 >> RIGHT. 1522 00:55:59,240 --> 00:56:03,800 WELL, PART OF THAT IS TO LOOK AT 1523 00:56:03,800 --> 00:56:04,680 INTERVENTIONS THAT WE ALREADY 1524 00:56:04,680 --> 00:56:07,200 KNOW ARE EFFECTIVE, AND THEN TO 1525 00:56:07,200 --> 00:56:09,960 SORT OF REALLY PUSH THE 1526 00:56:09,960 --> 00:56:11,040 IMPLEMENTATION RESEARCH. 1527 00:56:11,040 --> 00:56:13,040 AND THIS IS AN AREA WHERE WE'RE 1528 00:56:13,040 --> 00:56:17,840 STARTING TO REALLY KIND OF 1529 00:56:17,840 --> 00:56:19,160 LEARN -- WE'RE DEVELOPING A PLAY 1530 00:56:19,160 --> 00:56:22,440 BOOK AS TO HOW TO MOVE THIS KIND 1531 00:56:22,440 --> 00:56:25,720 OF RESEARCH ALONG, SO YEAH, 1532 00:56:25,720 --> 00:56:27,120 YOU'RE RIGHT, WE DON'T WANT TO 1533 00:56:27,120 --> 00:56:27,720 SIT ON THIS. 1534 00:56:27,720 --> 00:56:32,080 I MEAN, THIS IS A CRISIS. 1535 00:56:32,080 --> 00:56:35,440 AND JUST -- OBVIOUSLY WE'VE 1536 00:56:35,440 --> 00:56:37,320 RECOGNIZED THE OPIOID CRISIS, 1537 00:56:37,320 --> 00:56:38,840 THE PAIN CRISIS, BUT I THINK WE 1538 00:56:38,840 --> 00:56:40,400 HAVE A STRESS CRISIS RIGHT NOW. 1539 00:56:40,400 --> 00:56:41,920 IT'S MANIFESTING ITSELF ACROSS A 1540 00:56:41,920 --> 00:56:43,760 LOT OF DIFFERENT AREAS. 1541 00:56:43,760 --> 00:56:44,960 SO YEAH, WE'RE DEFINITELY GOING 1542 00:56:44,960 --> 00:56:46,640 TO TRY TO SEE AND LOOK FOR 1543 00:56:46,640 --> 00:56:51,320 CREATIVE WAYS TO PUSH THIS 1544 00:56:51,320 --> 00:56:51,560 QUICKLY. 1545 00:56:51,560 --> 00:56:51,760 HELEN? 1546 00:56:51,760 --> 00:56:52,880 WE CAN'T ACTUALLY SEE YOUR 1547 00:56:52,880 --> 00:56:58,200 VIDEO. 1548 00:56:58,200 --> 00:56:59,200 THERE WE GO. 1549 00:56:59,200 --> 00:57:01,920 >> SO JUST TO COMMENT ON THE 1550 00:57:01,920 --> 00:57:03,480 PREVIOUS COMMENT, YOU KNOW, THIS 1551 00:57:03,480 --> 00:57:06,120 IS A VERY IMPORTANT AREA, 1552 00:57:06,120 --> 00:57:08,120 ESPECIALLY WITH LONG COVID, AND 1553 00:57:08,120 --> 00:57:11,360 THE NEED IS ACCELERATED BY THE 1554 00:57:11,360 --> 00:57:16,080 PANDEMIC, AND WHAT WE DO, 1555 00:57:16,080 --> 00:57:16,720 ESPECIALLY MIND/BODY 1556 00:57:16,720 --> 00:57:21,320 INTERVENTIONS, IS PROVIDING 1557 00:57:21,320 --> 00:57:24,520 TOOLS FOR SELF-REGULATION. 1558 00:57:24,520 --> 00:57:26,080 THE AMOUNT OF PEOPLE NOW UNDER 1559 00:57:26,080 --> 00:57:27,360 STRESS, IT'S JUST IMPOSSIBLE TO 1560 00:57:27,360 --> 00:57:29,320 FIND PROVIDERS FOR EACH OF THEM, 1561 00:57:29,320 --> 00:57:33,600 SO IT HAS TO BE A PUBLIC 1562 00:57:33,600 --> 00:57:35,800 EDUCATIONAL CAMPAIGN ABOUT 1563 00:57:35,800 --> 00:57:37,120 SELF-REGULATION, STRESS 1564 00:57:37,120 --> 00:57:38,720 REDUCTION, AND I DON'T KNOW 1565 00:57:38,720 --> 00:57:41,360 WHETHER NCCIH HAS A MISSION LIKE 1566 00:57:41,360 --> 00:57:41,560 THIS. 1567 00:57:41,560 --> 00:57:43,560 >> OH, YES, ABSOLUTELY. 1568 00:57:43,560 --> 00:57:45,680 WELL, YOU KNOW, THE WHOLE -- 1569 00:57:45,680 --> 00:57:47,480 WHAT YOU'RE CALLING 1570 00:57:47,480 --> 00:57:49,000 SELF-REGULATION IS VERY, VERY 1571 00:57:49,000 --> 00:57:50,120 IMPORTANT, AND WE WANT TO 1572 00:57:50,120 --> 00:57:52,520 UNDERSTAND BETTER FROM A BASIC 1573 00:57:52,520 --> 00:57:55,240 SCIENCE POINT OF VIEW, WE 1574 00:57:55,240 --> 00:57:56,920 UNDERSTAND THE AUTONOMIC NERVOUS 1575 00:57:56,920 --> 00:57:58,520 SYSTEM IS VERY IMPORTANT HERE, 1576 00:57:58,520 --> 00:57:59,640 THE ENDOCRINE SYSTEM IS RELATED 1577 00:57:59,640 --> 00:58:02,280 TO OUR IMMUNE RESPONSES. 1578 00:58:02,280 --> 00:58:05,320 IT'S RELATED TO A LOT OF -- THE 1579 00:58:05,320 --> 00:58:07,200 FIELD OF INTEROCEPTION THAT WE 1580 00:58:07,200 --> 00:58:08,840 ARE REALLY KIND OF TRYING TO 1581 00:58:08,840 --> 00:58:09,720 UNDERSTAND BETTER. 1582 00:58:09,720 --> 00:58:11,800 WHAT ARE THE SENSORY QUEUES THAT 1583 00:58:11,800 --> 00:58:13,840 YOU GET FROM YOUR BODY TO EVEN 1584 00:58:13,840 --> 00:58:16,120 KNOW THAT YOU'RE STRESSED? 1585 00:58:16,120 --> 00:58:18,120 YOU KNOW, DIFFERENT PEOPLE FEEL 1586 00:58:18,120 --> 00:58:19,320 DIFFERENT WAYS, RIGHT? 1587 00:58:19,320 --> 00:58:20,440 AND SO THAT'S IMPORTANT. 1588 00:58:20,440 --> 00:58:21,760 THAT'S AN IMPORTANT PIECE OF IT. 1589 00:58:21,760 --> 00:58:25,360 AND THEN WHAT ARE SOME OF THE 1590 00:58:25,360 --> 00:58:27,840 PRACTICES THAT WE ALREADY KNOW 1591 00:58:27,840 --> 00:58:32,800 CAN BE REALLY IMPLEMENTED THAT 1592 00:58:32,800 --> 00:58:35,280 ARE EASY TO DO, DON'T REQUIRE 1593 00:58:35,280 --> 00:58:36,840 EXTENSIVE TRAINING. 1594 00:58:36,840 --> 00:58:38,120 BREATHING, FOR EXAMPLE, DEEP 1595 00:58:38,120 --> 00:58:41,440 BREATHING, SIMPLE HEAD TO TOE 1596 00:58:41,440 --> 00:58:42,720 RELAXATION, SIMPLE MINDFULNESS 1597 00:58:42,720 --> 00:58:43,640 EXERCISES THAT CAN BE KIND OF 1598 00:58:43,640 --> 00:58:45,040 SCALED DOWN SO THAT THEY'RE 1599 00:58:45,040 --> 00:58:45,520 ACCESSIBLE TO PEOPLE. 1600 00:58:45,520 --> 00:58:48,120 WE REALLY WANT TO TRY TO REALLY 1601 00:58:48,120 --> 00:58:49,520 EXPLORE WHAT IS THE BEST WAY 1602 00:58:49,520 --> 00:58:51,040 THAT THIS CAN BE PUT INTO THE 1603 00:58:51,040 --> 00:58:53,600 HANDS OF PEOPLE SO THAT THEY CAN 1604 00:58:53,600 --> 00:58:56,200 APPLY THIS TO THEIR DAILY LIVES. 1605 00:58:56,200 --> 00:58:58,480 AND REALLY HELP -- WE HAVE THIS 1606 00:58:58,480 --> 00:59:03,280 KIND OF NEW LITTLE -- WHAT DO 1607 00:59:03,280 --> 00:59:07,080 YOU CALL IT, PRESS RESET ON 1608 00:59:07,080 --> 00:59:07,400 STRESS. 1609 00:59:07,400 --> 00:59:09,880 HOW DO YOU HELP PEOPLE TO PRESS 1610 00:59:09,880 --> 00:59:10,720 RESET SEVERAL TIMES DURING THE 1611 00:59:10,720 --> 00:59:12,520 DAY SO THAT THEIR LEVELS OF 1612 00:59:12,520 --> 00:59:15,280 STRESS DON'T ACCUMULATE AND SORT 1613 00:59:15,280 --> 00:59:18,840 OF REALLY SORT OF BUILD UP OVER 1614 00:59:18,840 --> 00:59:20,280 THE COURSE OF A STRESSFUL DAY, 1615 00:59:20,280 --> 00:59:23,760 WHICH WE ALL HAVE TO DEAL WITH. 1616 00:59:23,760 --> 00:59:25,960 SO RIGHT, I THINK THIS ELEMENT 1617 00:59:25,960 --> 00:59:28,960 OF SELF REGULATION IS SO 1618 00:59:28,960 --> 00:59:29,800 IMPORTANT, WHAT YOU'RE TALKING 1619 00:59:29,800 --> 00:59:30,800 ABOUT, WE NEED TO UNDERSTAND 1620 00:59:30,800 --> 00:59:31,880 BETTER HOW TO GIVE PEOPLE TOOLS 1621 00:59:31,880 --> 00:59:34,320 SO THAT THEY CAN DO THIS EASILY, 1622 00:59:34,320 --> 00:59:35,400 OR AT LEAST, YOU KNOW -- 1623 00:59:35,400 --> 00:59:36,840 >> WELL, YOU KNOW, SO YOU HAVE 1624 00:59:36,840 --> 00:59:38,840 ALL THIS INFORMATION AVAILABLE 1625 00:59:38,840 --> 00:59:42,520 ON YOUR WEBSITE FOR THE PUBLIC, 1626 00:59:42,520 --> 00:59:45,600 FOR THE GENERAL PUBLIC ABOUT 1627 00:59:45,600 --> 00:59:47,000 SUPPLEMENTS, BUT CAN YOU DEVELOP 1628 00:59:47,000 --> 00:59:50,600 A SIMILAR KIND OF TOOLBOX ABOUT 1629 00:59:50,600 --> 00:59:51,480 SELF-REGULATION TOOLS THAT WE 1630 00:59:51,480 --> 00:59:51,960 KNOW ABOUT? 1631 00:59:51,960 --> 00:59:52,920 >> THAT'S A GREAT IDEA. 1632 00:59:52,920 --> 00:59:56,640 IN FACT, WE ARE WORKING WITH OUR 1633 00:59:56,640 --> 00:59:58,760 COMMUNICATIONS TEAM ABOUT REALLY 1634 00:59:58,760 --> 01:00:02,880 SORT OF REIMAGINING OUR STRESS 1635 01:00:02,880 --> 01:00:05,720 INFORMATION PACKET, AND I 1636 01:00:05,720 --> 01:00:07,160 THINK -- WE'LL TAKE YOUR 1637 01:00:07,160 --> 01:00:07,520 RECOMMENDATION. 1638 01:00:07,520 --> 01:00:08,800 I THINK THAT'S A FANTASTIC IDEA. 1639 01:00:08,800 --> 01:00:12,400 THANK YOU. 1640 01:00:12,400 --> 01:00:14,080 I THINK, RICK, YOU HAD A HAND 1641 01:00:14,080 --> 01:00:14,240 UP? 1642 01:00:14,240 --> 01:00:16,520 >> HE DID HAVE HIS HAND UP. 1643 01:00:16,520 --> 01:00:18,200 >> JUST TO PIGGY BACK REAL 1644 01:00:18,200 --> 01:00:20,400 SHORTLY, I THINK ONE REALLY 1645 01:00:20,400 --> 01:00:25,880 OPPORTUNITY FOR THIS SELF-CARE 1646 01:00:25,880 --> 01:00:28,840 MASS IMPLEMENTATION AND MAYBE 1647 01:00:28,840 --> 01:00:31,160 QUICKER CLINICAL TRIALS PROBABLY 1648 01:00:31,160 --> 01:00:33,200 WILL INVOLVE INTERNET 1649 01:00:33,200 --> 01:00:35,760 APPROACHES, MAYBE APP APPROACHES 1650 01:00:35,760 --> 01:00:36,720 FOR THINGS THAT ARE ALREADY 1651 01:00:36,720 --> 01:00:39,360 OBVIOUSLY WORKING FOR US, LIKE 1652 01:00:39,360 --> 01:00:41,520 MEDITATION IS A VERY OPTIMAL 1653 01:00:41,520 --> 01:00:43,840 ONE, AS WOULD BE LIKE 1654 01:00:43,840 --> 01:00:44,840 ACUPRESSURE, THAT CAN ALL BE 1655 01:00:44,840 --> 01:00:48,920 TAUGHT VIA AN APP. 1656 01:00:48,920 --> 01:00:50,800 AND THAT'S REALLY KIND OF THE 1657 01:00:50,800 --> 01:00:52,680 ONLY WAY I CAN SEE MANY SITES 1658 01:00:52,680 --> 01:00:54,120 WORKING TOGETHER TO POOL DATA 1659 01:00:54,120 --> 01:00:56,400 QUICKLY, WOULD HAVE TO HAVE 1660 01:00:56,400 --> 01:00:57,640 INTERVENTION THAT WOULD BE 1661 01:00:57,640 --> 01:00:58,600 ADMINISTERED FROM LIKE A LOCAL 1662 01:00:58,600 --> 01:01:01,440 HUB THAT WOULD BE SENT OUT VIA 1663 01:01:01,440 --> 01:01:03,760 SMARTPHONES OR WHAT HAVE YOU. 1664 01:01:03,760 --> 01:01:06,600 MAYBE LIKE A FUNDING OPPORTUNITY 1665 01:01:06,600 --> 01:01:07,240 THAT WOULD STIMULATE THAT KIND 1666 01:01:07,240 --> 01:01:09,640 OF A NETWORK WHERE THESE 1667 01:01:09,640 --> 01:01:10,400 EFFICACIOUS THINGS THAT WE 1668 01:01:10,400 --> 01:01:13,920 ALREADY KNOW WORK CAN BE 1669 01:01:13,920 --> 01:01:17,440 IMPLEMENTED REALLY QUICKLY. 1670 01:01:17,440 --> 01:01:19,680 SO ANYWAY, JUST KIND OF OBVIOUS 1671 01:01:19,680 --> 01:01:19,920 THINGS. 1672 01:01:19,920 --> 01:01:22,560 >> THIS IS DEFINITELY VERY GOOD 1673 01:01:22,560 --> 01:01:22,840 THOUGHTS. 1674 01:01:22,840 --> 01:01:24,280 >> JUST WANT TO BE MINDFUL OF 1675 01:01:24,280 --> 01:01:24,640 TIME. 1676 01:01:24,640 --> 01:01:27,040 WE'VE GOT LIKE 4 MINUTES LEFT 1677 01:01:27,040 --> 01:01:30,640 AND WE'VE GOT DR. SONNENBURG AND 1678 01:01:30,640 --> 01:01:31,520 DR. KNUTSON AND I THINK THAT 1679 01:01:31,520 --> 01:01:33,160 WILL PROBABLY TAKE US TO THE 1680 01:01:33,160 --> 01:01:33,760 LUNCH BREAK. 1681 01:01:33,760 --> 01:01:36,000 >> I'LL MAKE MINE REALLY QUICK. 1682 01:01:36,000 --> 01:01:37,960 JUST TO COMMENT ON DR. SHERMAN'S 1683 01:01:37,960 --> 01:01:39,040 COMMENT ABOUT THE RAPIDITY RANGE 1684 01:01:39,040 --> 01:01:40,040 OF MOTION THAT'S NEEDED, I THINK 1685 01:01:40,040 --> 01:01:41,600 THIS IS A REALLY KEY POINT. 1686 01:01:41,600 --> 01:01:42,480 ONE OF THE THINGS THAT I THINK 1687 01:01:42,480 --> 01:01:44,000 ABOUT WHEN I THINK ABOUT RAPID 1688 01:01:44,000 --> 01:01:46,080 TRIALS IS SAFETY AS WELL AS 1689 01:01:46,080 --> 01:01:47,240 EFFICACY, AND I THINK DIET IS 1690 01:01:47,240 --> 01:01:48,840 ONE OF THESE THINGS THAT WE 1691 01:01:48,840 --> 01:01:50,120 HAVEN'T PAID ENOUGH ATTENTION 1692 01:01:50,120 --> 01:01:50,280 TO. 1693 01:01:50,280 --> 01:01:53,200 I KNOW WE TALK ABOUT IT A LOT AT 1694 01:01:53,200 --> 01:01:54,440 NCCIH, AND THE PRECISION 1695 01:01:54,440 --> 01:01:56,080 NUTRITION COMPONENT OF ALL-OF-US 1696 01:01:56,080 --> 01:01:57,280 IS COMING, BUT I WORRY THAT THAT 1697 01:01:57,280 --> 01:01:59,360 MAY NOT EXPLORE ENOUGH DIETARY 1698 01:01:59,360 --> 01:02:00,880 DIVERSITY AND THAT IT MAY NOT BE 1699 01:02:00,880 --> 01:02:02,120 RAPID ENOUGH TURNAROUND. 1700 01:02:02,120 --> 01:02:08,120 SO JUST THINKING ABOUT WAYS 1701 01:02:08,120 --> 01:02:10,160 TO -- WE'RE DELIVERING MASSIVE 1702 01:02:10,160 --> 01:02:11,600 DOSES OF DRUG-LIKE COMPOUNDS TO 1703 01:02:11,600 --> 01:02:13,160 OUR BODIES THREE TIMES A DAY, 1704 01:02:13,160 --> 01:02:14,600 SOMETIMES MORE TIMES A DAY. 1705 01:02:14,600 --> 01:02:16,120 THAT'S MANIPULATING OUR 1706 01:02:16,120 --> 01:02:17,120 MICROBIOME AND THEN CHANGING ALL 1707 01:02:17,120 --> 01:02:18,320 OF OUR BIOLOGY, AND WHAT AN 1708 01:02:18,320 --> 01:02:19,520 OPPORTUNITY TO HAVE A HUGE 1709 01:02:19,520 --> 01:02:20,920 HEALTH IMPACT IF WE COULD 1710 01:02:20,920 --> 01:02:22,400 UNDERSTAND THAT AND LEVERAGE IT. 1711 01:02:22,400 --> 01:02:24,200 >> EXCELLENT POINT. 1712 01:02:24,200 --> 01:02:26,880 THANK YOU. 1713 01:02:26,880 --> 01:02:27,920 LORI, YOU HAVE THE LAST WORD. 1714 01:02:27,920 --> 01:02:28,480 >> ALL RIGHT. 1715 01:02:28,480 --> 01:02:29,720 I'LL BE QUICK. 1716 01:02:29,720 --> 01:02:31,040 IT'S REALLY RESTATING MANY OF -- 1717 01:02:31,040 --> 01:02:35,200 MUCH OF WHAT'S BEEN SAID, BUT 1718 01:02:35,200 --> 01:02:37,080 THE NCCIH WEBSITE HAS THE HEALTH 1719 01:02:37,080 --> 01:02:37,840 INFORMATION COMPONENT WHICH I 1720 01:02:37,840 --> 01:02:39,600 THINK IS FOR THE GENERAL PUBLIC, 1721 01:02:39,600 --> 01:02:41,640 AND THERE'S GREAT INFORMATION ON 1722 01:02:41,640 --> 01:02:43,160 THERE ABOUT STRESS, BUT I THINK 1723 01:02:43,160 --> 01:02:45,360 THAT HOW DO WE PACKAGE THIS FOR 1724 01:02:45,360 --> 01:02:46,920 THE GENERAL PUBLIC, AND I WOULD 1725 01:02:46,920 --> 01:02:49,360 ALSO SAY EMPLOYERS WHO HAVE A 1726 01:02:49,360 --> 01:02:51,320 GREAT INTEREST IN WHAT'S GOING 1727 01:02:51,320 --> 01:02:51,960 ON HERE. 1728 01:02:51,960 --> 01:02:53,520 HOW DO WE PACKAGE THIS AND MAKE 1729 01:02:53,520 --> 01:02:55,240 IT PROACTIVE VERSUS PASSIVE 1730 01:02:55,240 --> 01:02:58,000 WHERE PEOPLE HAVE TO FIND THE 1731 01:02:58,000 --> 01:03:01,160 SITE AND SO TO GET THROUGH THE 1732 01:03:01,160 --> 01:03:01,440 MATERIALS. 1733 01:03:01,440 --> 01:03:04,680 SO JUST A COMMENT ABOUT MORE 1734 01:03:04,680 --> 01:03:06,120 BROAD COMMUNICATION ABOUT THE 1735 01:03:06,120 --> 01:03:10,280 FINDINGS AROUND STRESS. 1736 01:03:10,280 --> 01:03:11,720 >> THAT'S GRACE. 1737 01:03:11,720 --> 01:03:14,320 ONE OF THE GREAT. 1738 01:03:14,320 --> 01:03:15,720 ONE OF THE AREAS I'VE PERSONALLY 1739 01:03:15,720 --> 01:03:17,480 BEEN INTERESTED IN GETTING MORE 1740 01:03:17,480 --> 01:03:18,560 INPUT FROM YOU ALL 1741 01:03:18,560 --> 01:03:21,200 COUNCILMEMBERS IS, HOW EASY IS 1742 01:03:21,200 --> 01:03:24,920 TO GET THE INFORMATION FROM OUR 1743 01:03:24,920 --> 01:03:25,800 WEBSITE? 1744 01:03:25,800 --> 01:03:27,000 YOU KNOW, REGARDING A LOT OF 1745 01:03:27,000 --> 01:03:28,000 THINGS. 1746 01:03:28,000 --> 01:03:29,640 THIS IS FOR PUBLIC BUT ALSO 1747 01:03:29,640 --> 01:03:32,120 WE'RE VERY INTERESTED ABOUT HOW 1748 01:03:32,120 --> 01:03:33,480 USER-FRIENDLY SOME OF OUR 1749 01:03:33,480 --> 01:03:35,200 INFORMATION REGARDING FUNDING 1750 01:03:35,200 --> 01:03:39,800 OPPORTUNITIES, REGARDING -- 1751 01:03:39,800 --> 01:03:40,920 WE'VE PAID A LOT OF ATTENTION TO 1752 01:03:40,920 --> 01:03:42,120 THAT OVER THE LAST COUPLE YEARS 1753 01:03:42,120 --> 01:03:47,080 AND TRIED TO IMPROVE THE 1754 01:03:47,080 --> 01:03:49,000 USABILITY AND MAKE IT EASIER FOR 1755 01:03:49,000 --> 01:03:50,240 PEOPLE TO SEARCH TO FUNDING 1756 01:03:50,240 --> 01:03:53,280 OPPORTUNITIES, TO SEARCH FOR 1757 01:03:53,280 --> 01:03:53,760 DIFFERENT EVENTS. 1758 01:03:53,760 --> 01:03:58,200 SO IF YOU HAVE ANY FEEDBACK ON 1759 01:03:58,200 --> 01:03:59,520 THAT, WE WOULD REALLY WELCOME 1760 01:03:59,520 --> 01:03:59,720 THAT. 1761 01:03:59,720 --> 01:04:03,240 >> JUST A VERY QUICK ONE. 1762 01:04:03,240 --> 01:04:04,320 I WOULD ADVOCATE FOR A BIGGER 1763 01:04:04,320 --> 01:04:05,240 TWITTER PRESENCE. 1764 01:04:05,240 --> 01:04:07,960 I DON'T SEE A LOT FROM YOU GUYS. 1765 01:04:07,960 --> 01:04:09,720 BUT THAT'S THE WAY FORWARD. 1766 01:04:09,720 --> 01:04:11,480 >> THANK YOU. 1767 01:04:11,480 --> 01:04:11,800 WELL, I KNOW. 1768 01:04:11,800 --> 01:04:12,960 >> THANK YOU, DR. HANEY. 1769 01:04:12,960 --> 01:04:14,520 >> WE NEED TO DO MORE. 1770 01:04:14,520 --> 01:04:16,600 >> SO THAT'S GOING TO BE THE 1771 01:04:16,600 --> 01:04:18,480 LAST COMMENT BEFORE WE BREAK FOR 1772 01:04:18,480 --> 01:04:20,360 LUNCH BUT I'M GOING TO USE THIS 1773 01:04:20,360 --> 01:04:21,320 TO SEGUE FOR A PLUG ACTUAL 1774 01:04:21,320 --> 01:04:25,400 LITTLE FOR THIS AFTERNOON'S MINI 1775 01:04:25,400 --> 01:04:27,800 SYMPOSIUM, WHICH IS GOING TO BE 1776 01:04:27,800 --> 01:04:29,160 ON CLINICAL TRIALS AND HOW THEY 1777 01:04:29,160 --> 01:04:31,080 ADDRESS STRESS IN DIFFERENT 1778 01:04:31,080 --> 01:04:32,840 CONTEXTS, AND PARTICULARLY HOW 1779 01:04:32,840 --> 01:04:34,400 THOSE TRIALS CAN BE HIGHLY 1780 01:04:34,400 --> 01:04:34,960 IMPACTFUL. 1781 01:04:34,960 --> 01:04:36,440 WE HAVE THREE GREAT PRESENTERS 1782 01:04:36,440 --> 01:04:38,560 WHO WILL BE COMING IN, 1783 01:04:38,560 --> 01:04:39,640 INVESTIGATORS TALKING ABOUT THIS 1784 01:04:39,640 --> 01:04:42,280 FROM DIFFERENT PERSPECTIVES, AND 1785 01:04:42,280 --> 01:04:44,680 WE WILL THEN HAVE ALSO A LOT OF 1786 01:04:44,680 --> 01:04:46,440 TIME OR AT LEAST SOME TIME FOR 1787 01:04:46,440 --> 01:04:50,240 COUNCIL TO INTERACT WITH THE 1788 01:04:50,240 --> 01:04:51,840 PRESENTATIONS AND WEIGH IN ON 1789 01:04:51,840 --> 01:04:54,160 THE DISCUSSIONS AND MAKING 1790 01:04:54,160 --> 01:04:55,080 SUGGESTIONS ON THIS VERY 1791 01:04:55,080 --> 01:04:57,240 IMPORTANT TOPIC. 1792 01:04:57,240 --> 01:04:58,680 SO HAVE A GOOD LUNCH. 1793 01:04:58,680 --> 01:05:00,320 WE'LL MEET BACK HERE AGAIN 1794 01:05:00,320 --> 01:05:04,560 PROMPTLY AT 1:20 P.M. EASTERN 1795 01:05:04,560 --> 01:05:06,240 TIME TO START OFF, AND THAT WILL 1796 01:05:06,240 --> 01:05:12,800 BE THE SESSION LED BY DR. D' 1797 01:05:12,800 --> 01:05:14,240 SOUZA, AND THAT WILL BE FOLLOWED 1798 01:05:14,240 --> 01:05:15,480 BY THE MINI SYMPOSIUM ON STRESS. 1799 01:05:15,480 --> 01:05:16,760 SO HAVE A GREAT LUNCH. 1800 01:05:16,760 --> 01:05:17,920 WELCOME BACK FROM LUNCH. 1801 01:05:17,920 --> 01:05:22,800 WE ARE GOING TO BE STARTING NOW, 1802 01:05:22,800 --> 01:05:23,960 RECONVENING THE OPEN SESSION OF 1803 01:05:23,960 --> 01:05:26,120 THE 80 MEETING OF THE NATIONAL 1804 01:05:26,120 --> 01:05:26,560 ADVISORY COUNCIL FOR 1805 01:05:26,560 --> 01:05:27,160 COMPLEMENTARY AND INTEGRATIVE 1806 01:05:27,160 --> 01:05:27,960 HEALTH. 1807 01:05:27,960 --> 01:05:32,800 AND DR. LANGEVIN, TAKE IT AWAY. 1808 01:05:32,800 --> 01:05:42,280 >> THANK YOU SO MUCH, DR. 1809 01:05:42,280 --> 01:05:42,600 DR. KHALSA. 1810 01:05:42,600 --> 01:05:46,320 IT'S MY PLEASURE TO INTRODUCE 1811 01:05:46,320 --> 01:05:47,440 DR. RENA D'SOUZA, DIRECTOR OF 1812 01:05:47,440 --> 01:05:49,000 THE NATIONAL INSTITUTE OF DENTAL 1813 01:05:49,000 --> 01:05:51,160 AND CRANIOFACIAL RESEARCH AT 1814 01:05:51,160 --> 01:05:52,000 NIH. 1815 01:05:52,000 --> 01:05:55,880 SHE OVERSEES NIDCR'S ANNUAL 1816 01:05:55,880 --> 01:05:57,840 BUDGET OF MORE THAN 1817 01:05:57,840 --> 01:05:59,480 $475 MILLION, WHICH SUPPORTS 1818 01:05:59,480 --> 01:06:00,360 BASIC, TRANSLATIONAL AND 1819 01:06:00,360 --> 01:06:03,200 CLINICAL RESEARCH IN AREAS OF 1820 01:06:03,200 --> 01:06:05,400 ORAL CANCER, OROFACIAL PAIN, 1821 01:06:05,400 --> 01:06:09,560 TOOTH DECAY, PERIODONTAL 1822 01:06:09,560 --> 01:06:13,480 DISEASE, SALIVARY GLAND 1823 01:06:13,480 --> 01:06:14,480 DYSFUNCTION AND ORAL 1824 01:06:14,480 --> 01:06:16,000 COMPLICATIONS OF SYSTEMIC 1825 01:06:16,000 --> 01:06:17,440 DISEASES. 1826 01:06:17,440 --> 01:06:19,720 DR. D'SOUZA HAS BEEN AT NIH NOW 1827 01:06:19,720 --> 01:06:21,040 FOR A COUPLE OF YEARS NOW. 1828 01:06:21,040 --> 01:06:23,560 SHE WAS ONE OF THE INSTITUTE 1829 01:06:23,560 --> 01:06:25,560 DIRECTORS THAT WAS RECRUITED AND 1830 01:06:25,560 --> 01:06:27,360 STARTED I BELIEVE RIGHT AT THE 1831 01:06:27,360 --> 01:06:28,760 BEGINNING OF THE PANDEMIC, IF 1832 01:06:28,760 --> 01:06:30,480 I'M CORRECT. 1833 01:06:30,480 --> 01:06:34,080 AND IT'S BEEN WONDERFUL TO HAVE 1834 01:06:34,080 --> 01:06:36,480 DR. D'SOUZA JOIN OUR NIH FAMILY, 1835 01:06:36,480 --> 01:06:38,880 AND WE'VE HAD MANY CONVERSATIONS 1836 01:06:38,880 --> 01:06:41,640 WHERE IT'S VERY CLEAR THAT HER 1837 01:06:41,640 --> 01:06:45,880 INTERESTS REALLY INCLUDE THE 1838 01:06:45,880 --> 01:06:47,320 RELATIONSHIP OF ORAL HEALTH TO 1839 01:06:47,320 --> 01:06:49,840 WHOLE PERSON HEALTH AS WELL AS 1840 01:06:49,840 --> 01:06:51,480 PREVENTION, AND WE ALSO SHARE A 1841 01:06:51,480 --> 01:06:54,240 LOT OF INTERESTS IN THE AREAS OF 1842 01:06:54,240 --> 01:06:56,200 PAIN. 1843 01:06:56,200 --> 01:06:56,840 DR. D'SOUZA HAS BEEN 1844 01:06:56,840 --> 01:06:58,720 INSTRUMENTAL IN REALLY FOSTERING 1845 01:06:58,720 --> 01:06:59,840 A LOT OF COLLABORATIONS THAT 1846 01:06:59,840 --> 01:07:01,320 WE'VE HAD ACROSS MANY 1847 01:07:01,320 --> 01:07:03,320 INSTITUTES, INCLUDING MYOFASCIAL 1848 01:07:03,320 --> 01:07:06,400 PAIN INITIATIVE, INCLUDING THE 1849 01:07:06,400 --> 01:07:07,560 REJOIN INITIATIVE, AND SO WE'RE 1850 01:07:07,560 --> 01:07:12,160 SO EXCITED TO HAVE HER COME IN 1851 01:07:12,160 --> 01:07:16,640 AND SPEAK TO OUR COUNCIL TO TELL 1852 01:07:16,640 --> 01:07:20,680 US ABOUT THE PRIORITIES OF NIDCR 1853 01:07:20,680 --> 01:07:22,440 AND ALSO MANY DIFFERENT AREAS 1854 01:07:22,440 --> 01:07:23,560 WHERE WE CAN COLLABORATE. 1855 01:07:23,560 --> 01:07:27,280 ON A PERSONAL LEVEL, MY OWN LAB 1856 01:07:27,280 --> 01:07:32,720 AT NIDCR IN THE INTRAMURAL 1857 01:07:32,720 --> 01:07:36,360 RESEARCH DIVISION AT NIDCR, AND 1858 01:07:36,360 --> 01:07:37,880 IT'S WONDERFUL THAT THERE ARE 1859 01:07:37,880 --> 01:07:41,400 SUCH A DIVERSE ARRAY OF 1860 01:07:41,400 --> 01:07:43,240 INVESTIGATORS AND INTRAMURAL 1861 01:07:43,240 --> 01:07:45,040 RESEARCHERS THAT REALLY SPAN 1862 01:07:45,040 --> 01:07:47,320 ACROSS SO VARIED AREAS OF 1863 01:07:47,320 --> 01:07:49,280 HEALTH. 1864 01:07:49,280 --> 01:07:51,920 SO DR. D'SOUZA'S OWN RESEARCH 1865 01:07:51,920 --> 01:07:54,680 INTERESTS FOCUS ON CRANIOFACIAL 1866 01:07:54,680 --> 01:07:56,520 DEVELOPMENT, GENETICS, TOOTH 1867 01:07:56,520 --> 01:07:57,600 DEVELOPMENT, AND REGENERATIVE 1868 01:07:57,600 --> 01:07:59,120 DENTAL MEDICINE. 1869 01:07:59,120 --> 01:08:00,720 SHE AND HER TEAM HAVE MADE 1870 01:08:00,720 --> 01:08:01,960 IMPORTANT ADVANCES IN THE FIELD 1871 01:08:01,960 --> 01:08:04,160 OF TISSUE ENGINEERING IN THE 1872 01:08:04,160 --> 01:08:06,160 CONTEXT OF DENTAL CARE. 1873 01:08:06,160 --> 01:08:08,640 PRIOR TO JOINING NIH, 1874 01:08:08,640 --> 01:08:09,920 DR. D'SOUZA WAS THE ASSISTANT 1875 01:08:09,920 --> 01:08:11,600 VICE PRESIDENT FOR ACADEMIC 1876 01:08:11,600 --> 01:08:13,240 AFFAIRS AND EDUCATION FOR HEALTH 1877 01:08:13,240 --> 01:08:15,120 SCIENCES AT THE UNIVERSITY OF 1878 01:08:15,120 --> 01:08:17,520 UTAH IN SALT LAKE CITY, WHERE 1879 01:08:17,520 --> 01:08:21,240 SHE ALSO SERVED AS PROFESSOR OF 1880 01:08:21,240 --> 01:08:22,240 DENTISTRY AND THE CHAIR OF THE 1881 01:08:22,240 --> 01:08:24,720 SCHOOL OF DENTISTRY AND 1882 01:08:24,720 --> 01:08:26,600 PROFESSOR OF NEUROBIOLOGY AND 1883 01:08:26,600 --> 01:08:28,040 ANATOMY AND PATHOLOGY AND 1884 01:08:28,040 --> 01:08:28,960 SURGERY IN THE SCHOOL OF 1885 01:08:28,960 --> 01:08:30,320 MEDICINE AND THE DEPARTMENT OF 1886 01:08:30,320 --> 01:08:30,880 BIOMEDICAL ENGINEERING. 1887 01:08:30,880 --> 01:08:32,840 IF THAT WASN'T ENOUGH, IN 2002, 1888 01:08:32,840 --> 01:08:35,040 SHE WAS SELECTED TO BE INAUGURAL 1889 01:08:35,040 --> 01:08:37,560 DEAN AT THE UNIVERSITY OF UTAH 1890 01:08:37,560 --> 01:08:38,520 SCHOOL OF DENTISTRY. 1891 01:08:38,520 --> 01:08:39,960 IN ADDITION TO BEING A HIGHLY 1892 01:08:39,960 --> 01:08:41,160 PRODUCTIVE RESEARCHER AND 1893 01:08:41,160 --> 01:08:43,440 LEADER, DR. D'SOUZA IS ALSO A 1894 01:08:43,440 --> 01:08:45,000 DEVOTED MENTOR AND CHAMPION OF 1895 01:08:45,000 --> 01:08:46,280 DIVERSITY IN THE BIOMEDICAL 1896 01:08:46,280 --> 01:08:47,400 RESEARCH WORKFORCE. 1897 01:08:47,400 --> 01:08:49,040 SHE HAS SERVED AS A VOLUNTEER 1898 01:08:49,040 --> 01:08:50,440 DENTIST FOR WOMEN IN NEED AND 1899 01:08:50,440 --> 01:08:52,720 PEOPLE STRUGGLING WITH 1900 01:08:52,720 --> 01:08:53,800 HOMELESSNESS IN SALT LAKE CITY, 1901 01:08:53,800 --> 01:08:57,160 DALLAS AND HOUSTON SINCE 1985. 1902 01:08:57,160 --> 01:08:58,280 DR. D'SOUZA RECEIVED HER 1903 01:08:58,280 --> 01:08:59,360 BACHELOR'S DEGREE IN DENTAL 1904 01:08:59,360 --> 01:09:00,760 SURGERY FROM THE UNIVERSITY OF 1905 01:09:00,760 --> 01:09:03,160 BOMBAY, INDIA AND EARNED A DDS 1906 01:09:03,160 --> 01:09:06,360 AS WELL AS PH.D. IN PATHOLOGY, 1907 01:09:06,360 --> 01:09:07,240 BIOMEDICAL SCIENCES FROM THE 1908 01:09:07,240 --> 01:09:08,680 UNIVERSITY OF TEXAS HEALTH 1909 01:09:08,680 --> 01:09:10,560 SCIENCE CENTER IN HOUSTON. 1910 01:09:10,560 --> 01:09:11,840 SO WELCOME, DR. D'SOUZA. 1911 01:09:11,840 --> 01:09:13,720 THANK YOU SO MUCH FOR COMING AND 1912 01:09:13,720 --> 01:09:15,560 SPEAKING TO OUR COUNCIL. 1913 01:09:15,560 --> 01:09:16,840 >> THANK YOU. 1914 01:09:16,840 --> 01:09:20,800 THANK YOU, HELENE. 1915 01:09:20,800 --> 01:09:22,320 I WOULD SAY AS A NEW DIRECTOR, I 1916 01:09:22,320 --> 01:09:24,240 WAS ACTUALLY SWORN IN OCTOBER OF 1917 01:09:24,240 --> 01:09:24,960 2020 VIRTUALLY. 1918 01:09:24,960 --> 01:09:27,440 IT BEEN VIRTUAL REALITY SINCE. 1919 01:09:27,440 --> 01:09:28,880 BUT THAT REALITY HAS BEEN MADE A 1920 01:09:28,880 --> 01:09:32,080 WHOLE LOT MORE PLEASANT BECAUSE 1921 01:09:32,080 --> 01:09:34,120 OF FELLOW COLLEAGUES LIKE HELENE 1922 01:09:34,120 --> 01:09:35,120 LANGEVIN, IT'S BEEN SUCH A 1923 01:09:35,120 --> 01:09:36,440 PLEASURE KNOWING YOU AND SEEING 1924 01:09:36,440 --> 01:09:40,280 YOU AS A REAL ADVOCATE AND 1925 01:09:40,280 --> 01:09:44,560 SHARING THE VALUES THAT WE AT 1926 01:09:44,560 --> 01:09:45,080 NIDCR UPHOLD VERY DEARLY. 1927 01:09:45,080 --> 01:09:47,040 SO I WANT TO BRING TO ALL OF YOU 1928 01:09:47,040 --> 01:09:50,240 MANY DPREETINGS FROM GRR 1929 01:09:50,240 --> 01:09:50,520 INSTITUTE. 1930 01:09:50,520 --> 01:09:51,440 WE HAVE A VERY IMPORTANT 1931 01:09:51,440 --> 01:09:53,400 PARTNERSHIP WITH NCCIH AND WE 1932 01:09:53,400 --> 01:09:55,480 INTEND TO ACTUALLY STRENGTHEN 1933 01:09:55,480 --> 01:09:58,560 THAT IN THE MONTHS AND YEARS TO 1934 01:09:58,560 --> 01:09:58,800 COME. 1935 01:09:58,800 --> 01:10:02,680 AND I WANT TO SAY THAT -- LET ME 1936 01:10:02,680 --> 01:10:03,440 GO INTO THE SLIDE HERE. 1937 01:10:03,440 --> 01:10:05,800 SO THE TITLE IS FAIRLY 1938 01:10:05,800 --> 01:10:06,080 EXPLANATORY. 1939 01:10:06,080 --> 01:10:08,600 I WANT TO STRESS THAT THROUGHOUT 1940 01:10:08,600 --> 01:10:09,920 THE PRESENTATION, AS I DESCRIBE 1941 01:10:09,920 --> 01:10:11,920 WHAT'S IN OUR PORTFOLIO, I'M 1942 01:10:11,920 --> 01:10:15,080 HOPING THAT YOU ALLOW YOURSELF 1943 01:10:15,080 --> 01:10:16,800 THE FREEDOM TO MAKE THE 1944 01:10:16,800 --> 01:10:18,800 CONNECTIONS BECAUSE THAT'S HOW 1945 01:10:18,800 --> 01:10:20,880 IDEAS ARE BORN. 1946 01:10:20,880 --> 01:10:22,720 SO EVEN THOUGH I'M NOT GOING TO 1947 01:10:22,720 --> 01:10:23,720 SPECIFY WHICH ONES UNTIL THE 1948 01:10:23,720 --> 01:10:25,240 VERY END, I DO HOPE THAT WE CAN 1949 01:10:25,240 --> 01:10:28,760 GAIN FROM THIS CONNECTIONS FROM 1950 01:10:28,760 --> 01:10:29,200 THIS TALK. 1951 01:10:29,200 --> 01:10:32,680 AND THERE'S NO OTHER TIME 1952 01:10:32,680 --> 01:10:33,680 ACTUALLY TO KNOW AND LEARN AND 1953 01:10:33,680 --> 01:10:34,880 FEEL THAT IMPORTANCE OF HUMAN 1954 01:10:34,880 --> 01:10:36,200 CONNECTIONS AS THE PANDEMIC HAS 1955 01:10:36,200 --> 01:10:38,280 TAUGHT US THESE LESSONS. 1956 01:10:38,280 --> 01:10:39,760 I LOVE THAT "TIME" MAGAZINE 1957 01:10:39,760 --> 01:10:42,320 COVER BECAUSE IT ACTUALLY TELLS 1958 01:10:42,320 --> 01:10:44,200 US THAT LIFE HAS CHANGED AND 1959 01:10:44,200 --> 01:10:45,640 WILL NEVER BE THE SAME, AND HOW 1960 01:10:45,640 --> 01:10:46,920 WE REDEFINE THE FUTURE IS REALLY 1961 01:10:46,920 --> 01:10:48,480 UP TO US. 1962 01:10:48,480 --> 01:10:50,120 WE LEARNED THAT NIMBLENESS AND 1963 01:10:50,120 --> 01:10:51,640 BEING FLEXIBLE WAS SO KEY, AND 1964 01:10:51,640 --> 01:10:53,280 THAT PARTNERSHIPS AND TEAM WORK 1965 01:10:53,280 --> 01:10:55,000 WERE ACTUALLY CRITICAL FOR 1966 01:10:55,000 --> 01:10:57,640 HEALTH-RELATED MATTERS. 1967 01:10:57,640 --> 01:11:00,400 I SWITCHED THE IIIs THAT WE IN 1968 01:11:00,400 --> 01:11:02,360 SCIENCE WOULD LABEL AS 1969 01:11:02,360 --> 01:11:08,600 IMMUNOLOGY, INFECTION AND 1970 01:11:08,600 --> 01:11:09,600 IMMUNITY. 1971 01:11:09,600 --> 01:11:10,800 INTEGRATION DOESN'T MEAN WE LOSE 1972 01:11:10,800 --> 01:11:12,960 OUR IDENTITY OR OUR ECOSYSTEM 1973 01:11:12,960 --> 01:11:13,440 NATURES. 1974 01:11:13,440 --> 01:11:14,720 IT MEANS WE CONNECT THE DOTS SO 1975 01:11:14,720 --> 01:11:16,360 THAT WE IMPROVE HEALTH FOR THE 1976 01:11:16,360 --> 01:11:19,000 INDIVIDUAL IN A HOLISTIC MANNER. 1977 01:11:19,000 --> 01:11:20,960 BUT SHARK TANK APPROACHES WORK, 1978 01:11:20,960 --> 01:11:24,560 THAT, IN FACT, WE LEARNED THAT 1979 01:11:24,560 --> 01:11:26,360 THERE WERE MANY DEFICIENCIES IN 1980 01:11:26,360 --> 01:11:27,840 OUR HEALTHCARE SYSTEM AND THEY 1981 01:11:27,840 --> 01:11:29,200 CONTINUE TO PERSIST. 1982 01:11:29,200 --> 01:11:34,840 IT WAS PRETTY OBVIOUS, AND THAT 1983 01:11:34,840 --> 01:11:35,440 INDIVIDUALS MOST DISADVANTAGED 1984 01:11:35,440 --> 01:11:36,400 ARE ACTUALLY THE ONES THAT 1985 01:11:36,400 --> 01:11:37,600 SUCCUMBED TO THE PANDEMIC EARLY 1986 01:11:37,600 --> 01:11:40,360 ON, AND THAT THE SOCIAL 1987 01:11:40,360 --> 01:11:41,320 DETERMINANTS REMAIN I THINK A 1988 01:11:41,320 --> 01:11:44,200 DETERRENT TO US ACHIEVING IDEAL 1989 01:11:44,200 --> 01:11:48,080 OPTIMUM HEALTH FOR INDIVIDUALS. 1990 01:11:48,080 --> 01:11:50,360 IN THE FIELD OF ORAL HEALTH, 1991 01:11:50,360 --> 01:11:51,240 TELEDENTISTRY ACTUALLY DID 1992 01:11:51,240 --> 01:11:52,640 IMPROVE ACCESS TO CARE, SO THAT 1993 01:11:52,640 --> 01:11:54,320 WAS WONDERFUL LESSONS LEARNED 1994 01:11:54,320 --> 01:11:55,720 THAT WE COULD ACTUALLY USE THESE 1995 01:11:55,720 --> 01:12:02,360 NEW TECHNOLOGIES AND TOOLS TO TO 1996 01:12:02,360 --> 01:12:03,800 GET THE HELP THEY NEEDED. 1997 01:12:03,800 --> 01:12:05,600 AND OF COURSE IT WAS SO OBVIOUS 1998 01:12:05,600 --> 01:12:06,800 THAT SCIENCE AND TECHNOLOGY 1999 01:12:06,800 --> 01:12:08,520 COUNTS AND THAT LEADERSHIP 2000 01:12:08,520 --> 01:12:08,760 MATTERS. 2001 01:12:08,760 --> 01:12:10,280 SO I'M VERY GRATEFUL THAT HELENE 2002 01:12:10,280 --> 01:12:12,040 IS AT THE HELM OF LEADING THE 2003 01:12:12,040 --> 01:12:13,680 CENTER OF INTEGRATIVE HEALTH AND 2004 01:12:13,680 --> 01:12:16,080 COMPLEMENTARY MEDICINE, REALLY, 2005 01:12:16,080 --> 01:12:20,240 WITH COLLABORATIONS IN MIND. 2006 01:12:20,240 --> 01:12:21,440 SO TO INTRODUCE TO YOU THE HUMAN 2007 01:12:21,440 --> 01:12:23,080 FACE, EACH ONE OF YOU ON THIS 2008 01:12:23,080 --> 01:12:24,760 PANEL HAS THIS UNIQUE IDENTITY, 2009 01:12:24,760 --> 01:12:27,920 THE SENSE OF SELF WORTH AND 2010 01:12:27,920 --> 01:12:31,080 WELL-BEING, AND IT COMES FROM 2011 01:12:31,080 --> 01:12:35,240 THAT UNIQUE FACE, RIGHT, THAT WE 2012 01:12:35,240 --> 01:12:36,200 SOMETIMES TAKE FOLKS FOR 2013 01:12:36,200 --> 01:12:36,640 GRANTED. 2014 01:12:36,640 --> 01:12:38,400 YOU JUST HAVE TO TALK TO A 2015 01:12:38,400 --> 01:12:39,480 HOMELESS INDIVIDUAL THAT'S 2016 01:12:39,480 --> 01:12:40,480 MISSING FRONT TEETH AND YOU PUT 2017 01:12:40,480 --> 01:12:41,440 THEM BACK ON AND LIFE CHANGES 2018 01:12:41,440 --> 01:12:42,880 FOR THAT INDIVIDUAL. 2019 01:12:42,880 --> 01:12:44,520 AND THERE'S SO MANY EXAMPLES 2020 01:12:44,520 --> 01:12:47,960 THAT I'LL COME TO THROUGHOUT THE 2021 01:12:47,960 --> 01:12:48,360 TALK. 2022 01:12:48,360 --> 01:12:49,800 NOW WHAT WE ARE VERY, VERY PROUD 2023 01:12:49,800 --> 01:12:51,200 TO OWN ARE THE BIOLOGICAL 2024 01:12:51,200 --> 01:12:54,480 SYSTEMS THAT, IN FACT, ARE 2025 01:12:54,480 --> 01:12:55,800 PARADIGMS FOR BIOLOGY, REALLY, 2026 01:12:55,800 --> 01:12:56,480 AND MEDICINE. 2027 01:12:56,480 --> 01:12:59,520 WE HAVE ENAMEL WHICH IS 2028 01:12:59,520 --> 01:13:00,520 IRREPLACEABLE, THE HARDEST 2029 01:13:00,520 --> 01:13:03,040 TISSUE IN MAMMALIAN SYSTEMS, WE 2030 01:13:03,040 --> 01:13:04,680 HAVE THE DISTINCT PATTERNING OF 2031 01:13:04,680 --> 01:13:05,400 THE CRANIOFACIAL COMPLEX WHICH 2032 01:13:05,400 --> 01:13:08,960 MEANS THAT SUTURES AND TEETH AND 2033 01:13:08,960 --> 01:13:12,760 THEIR ERUPTION AND SHEDDING ARE 2034 01:13:12,760 --> 01:13:14,760 VERY STRICTLY TIMED, WHICH MEANS 2035 01:13:14,760 --> 01:13:18,360 STRICT GENETIC CONTROL. 2036 01:13:18,360 --> 01:13:20,080 WE HAVE THE UNIQUE TONGUE AND 2037 01:13:20,080 --> 01:13:23,800 TASTE BUDS, SALIVA, WE HAVE 2038 01:13:23,800 --> 01:13:24,800 MICROBIOME UNIQUE FOR THE ORAL 2039 01:13:24,800 --> 01:13:25,680 CAVITY. 2040 01:13:25,680 --> 01:13:27,880 SO WE OWN THESE SYSTEMS THAT 2041 01:13:27,880 --> 01:13:29,280 WE'RE VERY PROUD OF BUT WITH 2042 01:13:29,280 --> 01:13:30,600 THEM COME A HOST OF CHALLENGES 2043 01:13:30,600 --> 01:13:31,800 BECAUSE THEY ALL IMPACT SMALL 2044 01:13:31,800 --> 01:13:33,320 SPACES THAT WE WORK IN AND SMALL 2045 01:13:33,320 --> 01:13:35,320 TISSUES, RIGHT? 2046 01:13:35,320 --> 01:13:37,720 SO FOR ALL OF THESE AMAZING 2047 01:13:37,720 --> 01:13:38,600 SYSTEMS, WE HAVE A SET OF 2048 01:13:38,600 --> 01:13:39,560 CHALLENGES THAT WE HAVE TO STEP 2049 01:13:39,560 --> 01:13:43,400 UP TO MEET. 2050 01:13:43,400 --> 01:13:44,480 THE ORAL CAVITY, MORE THAN 2051 01:13:44,480 --> 01:13:45,960 ANYTHING ELSE, IS THE PORT OF 2052 01:13:45,960 --> 01:13:47,800 ENTRY FOR THE COMMON RISK 2053 01:13:47,800 --> 01:13:49,120 FACTORS THAT IN FACT PREDISPOSE 2054 01:13:49,120 --> 01:13:51,200 IF NOT CONTRIBUTE TO 2055 01:13:51,200 --> 01:13:53,800 CARDIOVASCULAR DISEASE AND 2056 01:13:53,800 --> 01:13:54,240 METABOLIC SYNDROME. 2057 01:13:54,240 --> 01:13:56,760 WE CAN SEE CERTAIN SYSTEMIC 2058 01:13:56,760 --> 01:13:57,680 DISEASES MANIFESTED VERY EARLY 2059 01:13:57,680 --> 01:13:59,480 IN THE MOUTH AND SARS-COV-2 WAS 2060 01:13:59,480 --> 01:14:00,480 NO EXCEPTION. 2061 01:14:00,480 --> 01:14:01,520 THE FIRST THING TO GO TYPICALLY 2062 01:14:01,520 --> 01:14:02,680 IS THE LOSS OF TASTE. 2063 01:14:02,680 --> 01:14:05,080 AND THEN YOU LAND UP WITH DRY 2064 01:14:05,080 --> 01:14:07,920 MOUTH AND OTHER SCE SEQUELAE F 2065 01:14:07,920 --> 01:14:08,280 COVID-19. 2066 01:14:08,280 --> 01:14:10,240 WE ALSO CAN MONITOR HEALING AND 2067 01:14:10,240 --> 01:14:11,320 COMPLIANCE BY LOOKING AT THE 2068 01:14:11,320 --> 01:14:16,240 ORAL CAVITY, WE CAN LOOK AT A 2069 01:14:16,240 --> 01:14:17,520 PATIENT AND KNOW ABOUT AS LONG 2070 01:14:17,520 --> 01:14:20,960 AS LONG TERM 2071 01:14:20,960 --> 01:14:31,000 DRUG USE, MENTAL ILLNESS, CAN BE 2072 01:14:31,000 --> 01:14:31,720 CONTROLLED WITH COMPLIANCE AS 2073 01:14:31,720 --> 01:14:34,560 WELL AS SIMPLY MONITORING THE 2074 01:14:34,560 --> 01:14:38,120 PROGRESS TREATMENT THROUGH ORAL 2075 01:14:38,120 --> 01:14:39,200 TISSUES, SO THERE'S A LOT THERE 2076 01:14:39,200 --> 01:14:39,880 WE NEED TO KNOW. 2077 01:14:39,880 --> 01:14:41,360 NOW WHEN I READ THROUGH YOUR 2078 01:14:41,360 --> 01:14:43,040 WEBSITE AND WENT THROUGH YOUR 2079 01:14:43,040 --> 01:14:44,040 STRATEGIC PLAN AND I LOOKED AT 2080 01:14:44,040 --> 01:14:49,560 YOUR PRINCIPLE CORE MISSIONS, 2081 01:14:49,560 --> 01:14:52,560 THERE WAS SUCH AN OVERLAP WITH 2082 01:14:52,560 --> 01:14:54,360 WHAT WE AT NIDCR ACTUALLY CARE 2083 01:14:54,360 --> 01:14:54,560 ABOUT. 2084 01:14:54,560 --> 01:14:58,800 SO I HOPE THIS IS JUST THE 2085 01:14:58,800 --> 01:15:00,560 BEGINNING OF CONTINUING THE 2086 01:15:00,560 --> 01:15:04,200 JOURNEY SET UP BETWEEN MARTHA 2087 01:15:04,200 --> 01:15:06,360 SOMERMAN AND HELENE YEARS AGO. 2088 01:15:06,360 --> 01:15:08,480 SO JUST AN OVERVIEW, WHAT MAKES 2089 01:15:08,480 --> 01:15:09,960 US TICK, SO TO SPEAK, WHAT OUR 2090 01:15:09,960 --> 01:15:14,520 CHARGES ARE, WHAT WE ACTUALLY 2091 01:15:14,520 --> 01:15:16,000 TAKE ON BEYOND THE SCIENCE, WHAT 2092 01:15:16,000 --> 01:15:17,680 IS ACTUALLY HAPPENING TO ORAL 2093 01:15:17,680 --> 01:15:20,040 HEALTH AND THE STATUS IN THIS 2094 01:15:20,040 --> 01:15:20,280 COUNTRY? 2095 01:15:20,280 --> 01:15:21,240 VERY IMPORTANT TO KNOW WHAT THAT 2096 01:15:21,240 --> 01:15:21,600 IS. 2097 01:15:21,600 --> 01:15:25,520 IT POINTS TO SO MANY CHALLENGES, 2098 01:15:25,520 --> 01:15:26,200 LESSONS AND OPPORTUNITIES FOR 2099 01:15:26,200 --> 01:15:28,360 THE FUTURE, HOW WE ORGANIZE AND 2100 01:15:28,360 --> 01:15:29,920 OF COURSE OUR RESEARCH 2101 01:15:29,920 --> 01:15:34,840 HIGHLIGHTS JUST TO PICK A FEW. 2102 01:15:34,840 --> 01:15:36,800 ALL OF THESE ARE LEAD TO OUR 2103 01:15:36,800 --> 01:15:38,240 COLLABORATIONS RIGHT NOW ACROSS 2104 01:15:38,240 --> 01:15:39,600 CAMPUS, ACROSS INSTITUTES AND OF 2105 01:15:39,600 --> 01:15:40,880 COURSE OUR EXTRAMURAL 2106 01:15:40,880 --> 01:15:42,400 INVESTMENTS, SO THAT WE CAN MAKE 2107 01:15:42,400 --> 01:15:46,680 MORE CONNECTIONS WITH NCCIH. 2108 01:15:46,680 --> 01:15:52,680 SO WE'RE ONE OF 20 INSTITUTES. 2109 01:15:52,680 --> 01:15:54,400 WE'RE I THINK ON THE SMALLER 2110 01:15:54,400 --> 01:15:55,640 END, OUR BUDGET ACTUALLY, 2111 01:15:55,640 --> 01:15:59,280 HELENE, MOVED UP TO 500 MILLION 2112 01:15:59,280 --> 01:16:00,800 AND 200 ODD THOUSAND DOLLARS SO 2113 01:16:00,800 --> 01:16:02,800 WE MOVED BEYOND THE 500 MARK, 2114 01:16:02,800 --> 01:16:04,520 WHICH IS WONDERFUL, BUT WHAT 2115 01:16:04,520 --> 01:16:06,600 MAKES US DISTINCT IN MANY WAYS 2116 01:16:06,600 --> 01:16:07,680 WAS OUR ACTUAL HISTORY. 2117 01:16:07,680 --> 01:16:08,920 WE WERE CREATED 48 YEARS AGO. 2118 01:16:08,920 --> 01:16:15,680 SO WE CELEBRATED CELEBRATT 2119 01:16:15,680 --> 01:16:20,840 YEAR ALONG WITH NEI AND GARY 2120 01:16:20,840 --> 01:16:21,720 GIBBONS, NHLBI. 2121 01:16:21,720 --> 01:16:23,240 WE WERE CREATED WITH A PUBLIC 2122 01:16:23,240 --> 01:16:24,320 HEALTH MISSION. 2123 01:16:24,320 --> 01:16:27,720 HARRY TRUMAN WAS CONCERNED WITH 2124 01:16:27,720 --> 01:16:29,000 THOSE BEING ENLISTED IN THE WAR 2125 01:16:29,000 --> 01:16:29,760 COULDN'T BECAUSE THEY HAD VERY 2126 01:16:29,760 --> 01:16:30,560 BAD ORAL HEALTH. 2127 01:16:30,560 --> 01:16:32,440 A LOT OF DECAY AT THAT TIE. 2128 01:16:32,440 --> 01:16:36,040 PRIOR TO THE INTRODUCTION OF 2129 01:16:36,040 --> 01:16:37,120 FLUORIDE IN COMMUNITY WATER 2130 01:16:37,120 --> 01:16:37,800 SYSTEMS. 2131 01:16:37,800 --> 01:16:39,800 SO WE CHANGED OUR NAME TO NIDCR 2132 01:16:39,800 --> 01:16:41,640 TO INCLUDE THE CRANIOFACIAL 2133 01:16:41,640 --> 01:16:42,920 COMPLEX FOR THE REASONS I 2134 01:16:42,920 --> 01:16:46,240 MENTIONED JUST EARLIER. 2135 01:16:46,240 --> 01:16:47,680 AND WE STAY TRUE TO THAT MISSION 2136 01:16:47,680 --> 01:16:50,080 TODAY, WHICH IS TO REALLY 2137 01:16:50,080 --> 01:16:50,840 ADVANCE HEALTH THROUGH 2138 01:16:50,840 --> 01:16:52,120 KNOWLEDGE, THROUGH DISCOVERIES, 2139 01:16:52,120 --> 01:16:54,720 THROUGH PARTNERSHIPS. 2140 01:16:54,720 --> 01:16:58,480 BECAUSE WE CAN'T TO TO DO IT R 2141 01:16:58,480 --> 01:16:58,720 OWN. 2142 01:16:58,720 --> 01:17:00,760 WHEN I CAME ON BOARD, LITTLE DID 2143 01:17:00,760 --> 01:17:01,880 I KNOW THAT WE WOULD HAVE TO 2144 01:17:01,880 --> 01:17:03,760 TAKE ON THE RESPONSIBILITY OF 2145 01:17:03,760 --> 01:17:05,320 STEERING THIS REPORT WHICH WAS 2146 01:17:05,320 --> 01:17:08,720 ON THE ORAL HEALTH STATUS OF THE 2147 01:17:08,720 --> 01:17:10,760 COUNTRY, THE PREVIOUS SURGEON 2148 01:17:10,760 --> 01:17:12,840 GENERAL, JEROME ADAMS, WAS 2149 01:17:12,840 --> 01:17:14,240 REALLY STRUCK BY THE DEMANDS OF 2150 01:17:14,240 --> 01:17:16,640 COVID AND WAS UNABLE TO SHEPPARD 2151 01:17:16,640 --> 01:17:18,200 THE TRUTH FURTHER, AND THE NEW 2152 01:17:18,200 --> 01:17:20,160 SURGEON GENERAL HAD THE BORDER 2153 01:17:20,160 --> 01:17:23,320 CRISIS, MENTAL HEALTH AND OTHER 2154 01:17:23,320 --> 01:17:24,400 RESPONSIBILITIES SO WE KIND OF 2155 01:17:24,400 --> 01:17:25,320 FELL IN THE CRACK THERE. 2156 01:17:25,320 --> 01:17:29,040 AND NIH STEPPED UP WITH NIDCR TO 2157 01:17:29,040 --> 01:17:30,040 GUIDE IT THROUGH. 2158 01:17:30,040 --> 01:17:33,200 IT'S A 790-PAGE DOCUMENT. 2159 01:17:33,200 --> 01:17:34,760 THE EXECUTIVE SUMMARY IS ONLY 25 2160 01:17:34,760 --> 01:17:36,520 PAGES SO I URGE YOU TO READ 2161 01:17:36,520 --> 01:17:37,040 THAT. 2162 01:17:37,040 --> 01:17:38,800 I'VE PLACED THE LINK HERE AND I 2163 01:17:38,800 --> 01:17:41,960 WILL LEAVE THE POWERPOINT WITH 2164 01:17:41,960 --> 01:17:44,840 YOU. 2165 01:17:44,840 --> 01:17:47,080 THE WAY WE PROCEEDED WAS TO 2166 01:17:47,080 --> 01:17:48,240 ORGANIZE ACROSS THE LIFESPAN 2167 01:17:48,240 --> 01:17:49,720 LOOKING AT DISEASES AND 2168 01:17:49,720 --> 01:17:52,640 DISORDERS THAT REALLY 2169 01:17:52,640 --> 01:17:53,360 CHARACTERIZE EACH AGE GROUP AND 2170 01:17:53,360 --> 01:17:56,520 ALSO PICKED ON WHAT I CONSIDERED 2171 01:17:56,520 --> 01:17:58,720 THE CROSS-CUTTING THEMES OF PAIN 2172 01:17:58,720 --> 01:17:59,720 IMAGINAGEMENT, OPIOID, SUBSTANCE 2173 01:17:59,720 --> 01:18:02,240 USE DISORDERS, ADDICTIONS OF 2174 01:18:02,240 --> 01:18:03,000 DIFFERENT KINDS. 2175 01:18:03,000 --> 01:18:05,400 SO WE'RE HOPING THAT IT WILL 2176 01:18:05,400 --> 01:18:06,600 STAY AS A LIVING DOCUMENT AND 2177 01:18:06,600 --> 01:18:09,440 HELP US GUIDE OUR THINKING AND 2178 01:18:09,440 --> 01:18:12,840 OUR STRATEGIES FOR THE FUTURE. 2179 01:18:12,840 --> 01:18:15,920 AND IT WAS GOOD WITH THE HELP OF 2180 01:18:15,920 --> 01:18:16,720 LARRY TABAK, WE WERE ABLE TO 2181 01:18:16,720 --> 01:18:18,440 STRIKE UP A COLLABORATION WITH 2182 01:18:18,440 --> 01:18:19,960 DR. VIVEK MURTHY, WHO'S THE 2183 01:18:19,960 --> 01:18:22,120 CURRENT SURGEON GENERAL, AND WE 2184 01:18:22,120 --> 01:18:23,120 WROTE THIS SHORT PERSPECTIVE 2185 01:18:23,120 --> 01:18:24,720 ARTICLE PUBLISHED IN THE NEW 2186 01:18:24,720 --> 01:18:26,200 ENGLAND JOURNAL, AND THIS IS A 2187 01:18:26,200 --> 01:18:29,040 QUOTE FROM THERE THAT BASICALLY 2188 01:18:29,040 --> 01:18:31,320 STRIKES AT THE VERY CORE OF WHAT 2189 01:18:31,320 --> 01:18:34,400 WE ACTUALLY REPORTED ON. 2190 01:18:34,400 --> 01:18:36,080 AND IT WAS IN MANY WAYS AN 2191 01:18:36,080 --> 01:18:38,040 UPLIFTING EXPERIENCE BECAUSE WE 2192 01:18:38,040 --> 01:18:38,800 ACKNOWLEDGED ALL THE GOOD 2193 01:18:38,800 --> 01:18:41,200 SCIENCE AND DISCOVERIES THAT 2194 01:18:41,200 --> 01:18:42,560 CAME ABOUT IN THE LAST 20 YEARS, 2195 01:18:42,560 --> 01:18:43,880 SO THE FIRST SURGEON GENERAL 2196 01:18:43,880 --> 01:18:46,680 REPORT WAS PUBLISHED IN 2000. 2197 01:18:46,680 --> 01:18:48,680 AND THAT WAS A REPORT THAT 2198 01:18:48,680 --> 01:18:49,360 STRESSED THE CONNECTION BETWEEN 2199 01:18:49,360 --> 01:18:52,520 THE ORAL SYSTEMS AND SYSTEMIC -- 2200 01:18:52,520 --> 01:18:54,480 GENERAL SYSTEMS. 2201 01:18:54,480 --> 01:18:56,240 BUT DESPITE ALL OF THE PROGRESS 2202 01:18:56,240 --> 01:18:58,880 WE'VE MADE, WE STILL HAVE THIS 2203 01:18:58,880 --> 01:18:59,960 HUGE PROBLEM WHERE INDIVIDUALS 2204 01:18:59,960 --> 01:19:02,080 AND POPULATIONS IN THIS COUNTRY 2205 01:19:02,080 --> 01:19:03,160 EXPERIENCE ORAL HEALTH 2206 01:19:03,160 --> 01:19:04,200 DIFFERENTLY. 2207 01:19:04,200 --> 01:19:05,520 AND THAT WE CANNOT LOOK AT 2208 01:19:05,520 --> 01:19:07,200 HEALTH AND WELL-BEING WITHOUT 2209 01:19:07,200 --> 01:19:10,880 CONSIDERING ORAL HEALTHCARE AS 2210 01:19:10,880 --> 01:19:12,560 BEING ABSOLUTELY INEXTRICABLY 2211 01:19:12,560 --> 01:19:14,320 LINKED TO GENERAL HEALTH. 2212 01:19:14,320 --> 01:19:15,600 SO OVER THE LAST 20 YEARS WE ALL 2213 01:19:15,600 --> 01:19:19,400 KNOW THE DEMOGRAPHICS HAVE 2214 01:19:19,400 --> 01:19:19,880 CHANGED SIGNIFICANTLY. 2215 01:19:19,880 --> 01:19:21,840 WE'VE MOVED ESPECIALLY IN ORAL 2216 01:19:21,840 --> 01:19:23,720 HEALTH TO A VERY DIGITAL ERA. 2217 01:19:23,720 --> 01:19:25,240 WE'RE LOOKING NOW AT DATA 2218 01:19:25,240 --> 01:19:27,320 SCIENCE AND BIG DATA, THE 2219 01:19:27,320 --> 01:19:29,040 DELIVERY OF SYSTEMS AND OUR 2220 01:19:29,040 --> 01:19:31,040 DELIVERABLES HAVE CHANGED, WHAT 2221 01:19:31,040 --> 01:19:32,120 PATIENTS EXPECT THE KINDS AND 2222 01:19:32,120 --> 01:19:35,000 SCOPES OF PRACTICES HAVE 2223 01:19:35,000 --> 01:19:36,200 CHANGED, OUR DISEASE TRENDS HAVE 2224 01:19:36,200 --> 01:19:39,560 CHANGED TO WHERE HBV POSITIVE 2225 01:19:39,560 --> 01:19:40,760 OROPHARYNGEAL CANCERS ARE NOW 2226 01:19:40,760 --> 01:19:43,920 MORE DOMINANT THAN CERVICAL 2227 01:19:43,920 --> 01:19:47,240 CANCERS OF HBV ORIGIN. 2228 01:19:47,240 --> 01:19:48,760 OUR DISCOVERIES HAVE BEEN 2229 01:19:48,760 --> 01:19:49,760 FANTASTIC BUT WE HAVE THE 2230 01:19:49,760 --> 01:19:50,760 DIVIDES AND BARRIERS AND 2231 01:19:50,760 --> 01:19:51,640 DETERMINANTS OF HEALTH THAT HOLD 2232 01:19:51,640 --> 01:19:55,600 US BACK, ALONG WITH UNEXPECTED 2233 01:19:55,600 --> 01:19:56,440 PANDEMICS THAT WE'RE NOT QUITE 2234 01:19:56,440 --> 01:19:58,040 PREPARED FOR. 2235 01:19:58,040 --> 01:20:00,720 AND THIS IS WHAT THE REPORT 2236 01:20:00,720 --> 01:20:01,200 SAYS. 2237 01:20:01,200 --> 01:20:03,120 THAT THE BURDEN OF ORAL DISEASE 2238 01:20:03,120 --> 01:20:06,760 IS HUGE AND IT'S FELT GLOBALLY. 2239 01:20:06,760 --> 01:20:08,400 CRANIOFACIAL DEFECTS OUT OF ALL 2240 01:20:08,400 --> 01:20:10,360 THE INHERITED DISORDERS, 50% OF 2241 01:20:10,360 --> 01:20:12,320 THEM INVOLVE THE CRANIOFACIAL 2242 01:20:12,320 --> 01:20:12,920 COMPLEX. 2243 01:20:12,920 --> 01:20:14,280 I BRING THAT UP, I KNOW I HAVE 2244 01:20:14,280 --> 01:20:16,040 IN THE PAST TO HELENE THAT 2245 01:20:16,040 --> 01:20:18,920 THAT'S AN AREA THAT IS HARDLY 2246 01:20:18,920 --> 01:20:19,200 UNDERSTOOD. 2247 01:20:19,200 --> 01:20:21,480 LITTLE BABIES HAVE TO ENDURE 2248 01:20:21,480 --> 01:20:23,840 LONG HOURS OF SURGERY AND THEN 2249 01:20:23,840 --> 01:20:25,160 LIFELONG MANAGEMENT INVOLVING A 2250 01:20:25,160 --> 01:20:27,240 LOT OF FACIAL TISSUES AND A LOT 2251 01:20:27,240 --> 01:20:28,720 OF MUSCULATURE AND THEY FALL 2252 01:20:28,720 --> 01:20:31,960 INTO THIS KIND OF CRACK OF NOT 2253 01:20:31,960 --> 01:20:33,440 BEING ATTENDED TO FULLY WELL. 2254 01:20:33,440 --> 01:20:37,400 DENTAL DECAY OR CARE EAST, WHICH 2255 01:20:37,400 --> 01:20:39,840 IS REALLY THE MOST PREVALENT OF 2256 01:20:39,840 --> 01:20:42,880 ALL CHILDHOOD DISEASE, THE 2257 01:20:42,880 --> 01:20:45,200 COMMON REASON WHY CHILDREN MISS 2258 01:20:45,200 --> 01:20:48,240 SCHOOL AND ARE TAKEN TO THE E.R. 2259 01:20:48,240 --> 01:20:49,560 YOU'RE SUPPOSED TO ACCESS A 2260 01:20:49,560 --> 01:20:51,760 DENTIST WHERE OFTENTIMES YOU 2261 01:20:51,760 --> 01:20:52,760 CAN'T. 2262 01:20:52,760 --> 01:20:54,720 SEVERE PERIODONTITIS REMAINS AN 2263 01:20:54,720 --> 01:20:57,160 ADULT DISEASE, VERY COMMON, ONE 2264 01:20:57,160 --> 01:20:58,840 OF THE MOST COMMON OF ALL 2265 01:20:58,840 --> 01:20:59,280 INFECTIOUS DISEASES. 2266 01:20:59,280 --> 01:21:00,720 AND THEN, OF COURSE, WE HAVE THE 2267 01:21:00,720 --> 01:21:02,880 CANCERS, VERY HARD TO DETECT, 2268 01:21:02,880 --> 01:21:07,200 ALWAYS DETECTED TOO LATE, 2269 01:21:07,200 --> 01:21:08,240 TREATMENT IS SURGICAL RESECTION 2270 01:21:08,240 --> 01:21:09,400 WHERE HALF THE TONGUE IS REMOVED 2271 01:21:09,400 --> 01:21:10,840 AND THEN YOU HAVE THIS VERY 2272 01:21:10,840 --> 01:21:12,440 PAINFUL RECOVERY PROCESS FOR 2273 01:21:12,440 --> 01:21:16,080 WHICH THERE ISN'T ANY -- REALLY 2274 01:21:16,080 --> 01:21:17,920 NO MEDICATIONS THAT CAN 2275 01:21:17,920 --> 01:21:19,240 ALLEVIATE SOME OF THIS PAIN AND 2276 01:21:19,240 --> 01:21:20,920 DISCOMFORT. 2277 01:21:20,920 --> 01:21:23,160 AND OF COURSE HPV RISING TO 2278 01:21:23,160 --> 01:21:24,040 CERVICAL CANCER, HIGHER THAN 2279 01:21:24,040 --> 01:21:24,440 THAT. 2280 01:21:24,440 --> 01:21:26,920 THIS IS JUST AN EXAMPLE WHAT 2281 01:21:26,920 --> 01:21:28,200 CHILDHOOD CARE EAST CAN DO TO 2282 01:21:28,200 --> 01:21:29,320 INDIVIDUALS. 2283 01:21:29,320 --> 01:21:33,800 YOU START A CHILD WITH THAT -- A 2284 01:21:33,800 --> 01:21:35,200 MOUTHFUL OF DECAY, THAT CHILD IS 2285 01:21:35,200 --> 01:21:36,640 SET FOR LIFE FROM THEN ON. 2286 01:21:36,640 --> 01:21:39,200 TYPICALLY THEY GO INTO SURGERY, 2287 01:21:39,200 --> 01:21:41,120 EITHER HAVING TO HAVE LOTS OF 2288 01:21:41,120 --> 01:21:43,080 EXTRACTIONS OR STAINLESS STEEL 2289 01:21:43,080 --> 01:21:45,080 CROWNS, AND IT'S VERY PREVALENT 2290 01:21:45,080 --> 01:21:46,280 IN THIS COUNTRY. 2291 01:21:46,280 --> 01:21:52,920 AND YOU CAN SEE TO THE VERY FAR 2292 01:21:52,920 --> 01:21:54,120 RIGHT, ONE WHO WAS NEGLECTED, IT 2293 01:21:54,120 --> 01:21:55,240 SPREAD TO HIS BRAIN, 2294 01:21:55,240 --> 01:21:56,000 UNFORTUNATELY HE DIED BECAUSE 2295 01:21:56,000 --> 01:21:57,120 THERE WAS NO CARE. 2296 01:21:57,120 --> 01:21:58,960 HE WASN'T GIVEN THE CARE HE 2297 01:21:58,960 --> 01:21:59,360 NEEDED. 2298 01:21:59,360 --> 01:22:01,720 SO I KNOW I'M EMPHASIZING PUBLIC 2299 01:22:01,720 --> 01:22:04,560 HEALTH HERE BUT IT'S ALL GUIDED 2300 01:22:04,560 --> 01:22:07,280 BY OUR SCIENCE OR OUR NEED TO 2301 01:22:07,280 --> 01:22:08,480 LOOK AT A DIFFERENT WAY TO 2302 01:22:08,480 --> 01:22:09,720 HANDLE OUR DISEASES AND 2303 01:22:09,720 --> 01:22:10,880 PROBLEMS. 2304 01:22:10,880 --> 01:22:13,640 RISING AND ALSO VERY NE NEGLED 2305 01:22:13,640 --> 01:22:15,720 ARE THE TRIBAL NATIONS, WHERE A 2306 01:22:15,720 --> 01:22:19,680 COMBINATION OF ACCESS TO ONLY 2307 01:22:19,680 --> 01:22:21,000 WELL WATER THAT HAS A LOT OF 2308 01:22:21,000 --> 01:22:21,680 ENVIRONMENTAL STRESSES AND 2309 01:22:21,680 --> 01:22:30,360 TOXINS WITH PHENOLS AND FAIL S 2310 01:22:30,360 --> 01:22:31,560 CONTRIBUTE TO ORAL HEALTH, DECAY 2311 01:22:31,560 --> 01:22:33,000 IS SO HIGH AMONGST THESE 2312 01:22:33,000 --> 01:22:34,760 POPULATIONS AS IT IS AMONGST 2313 01:22:34,760 --> 01:22:35,360 HISPANICS AND AFRICAN AMERICANS 2314 01:22:35,360 --> 01:22:36,760 WHO HAVE NO ACCESS TO CARE, AND 2315 01:22:36,760 --> 01:22:38,160 THAT'S EXACTLY WHAT A TYPICAL 2316 01:22:38,160 --> 01:22:38,960 MOUTH LOOKS LIKE. 2317 01:22:38,960 --> 01:22:40,600 AND I'VE BEEN THERE AND TREATED 2318 01:22:40,600 --> 01:22:43,960 THESE PATIENTS. 2319 01:22:43,960 --> 01:22:47,400 SO WE'VE REALIZED THROUGH SOUL 2320 01:22:47,400 --> 01:22:48,720 SEARCHING, WHICH WASN'T WHAT WE 2321 01:22:48,720 --> 01:22:49,880 WERE THINKING 20 YEARS AGO AND 2322 01:22:49,880 --> 01:22:51,880 IS SO CENTRAL TO NCCIH IS THAT 2323 01:22:51,880 --> 01:22:54,480 WE LOOK AT A PATIENT AS A WHOLE. 2324 01:22:54,480 --> 01:22:57,000 AND AS WE TREAT INDIVIDUAL 2325 01:22:57,000 --> 01:22:58,200 CONDITIONS, THAT WE PUT THAT 2326 01:22:58,200 --> 01:22:59,640 PATIENT IN THE CONTEXT OF THEIR 2327 01:22:59,640 --> 01:23:01,840 FAMILY SETTINGS AND THEIR 2328 01:23:01,840 --> 01:23:04,120 COMMUNITY LEVEL INFLUENCES AND 2329 01:23:04,120 --> 01:23:05,960 YOU LOOK AT BEST WAYS TO 2330 01:23:05,960 --> 01:23:08,480 MITIGATE THESE NEGATIVE UPSTREAM 2331 01:23:08,480 --> 01:23:11,360 DETERMINANTS THAT REALLY IN THE 2332 01:23:11,360 --> 01:23:13,080 END PUSH SOMEONE INTO THE 2333 01:23:13,080 --> 01:23:15,720 DISEASE PATH. 2334 01:23:15,720 --> 01:23:17,240 THAT HAS BECOME AN ISSUE FOR 2335 01:23:17,240 --> 01:23:19,400 GLOBAL HEALTH CONCERN ABSOLUTELY 2336 01:23:19,400 --> 01:23:22,280 SO AND STRESSED BY WHO ACTUALLY 2337 01:23:22,280 --> 01:23:24,720 PASSING A RESOLUTION THAT ORAL 2338 01:23:24,720 --> 01:23:27,000 HEALTHCARE SHOULD BE PART OF 2339 01:23:27,000 --> 01:23:28,520 UNIVERSAL HEALTH COVERAGE, SO 2340 01:23:28,520 --> 01:23:29,360 SAYING IT IS ABSOLUTELY 2341 01:23:29,360 --> 01:23:32,720 ESSENTIAL FOR OVERALL HEALTH AND 2342 01:23:32,720 --> 01:23:33,040 WELL-BEING. 2343 01:23:33,040 --> 01:23:40,280 IT IS SO NICE WHEN THE OLDEST OF 2344 01:23:40,280 --> 01:23:41,920 WORLD CLASS JOURNALS PUT AN 2345 01:23:41,920 --> 01:23:43,120 EMPHASIS ON ORAL HEALTH BY 2346 01:23:43,120 --> 01:23:45,400 PUBLISHING A SPECIAL SERIES IN 2347 01:23:45,400 --> 01:23:46,520 2019 THAT EMPHASIZED THE 2348 01:23:46,520 --> 01:23:48,040 IMPORTANCE OF EVIDENCE OF 2349 01:23:48,040 --> 01:23:51,440 ADDRESSING THE DETERMINANTS, 2350 01:23:51,440 --> 01:23:52,320 TACKLING INEQUALITIES AND 2351 01:23:52,320 --> 01:23:53,640 ACTUALLY CHANGING THE WAY WE 2352 01:23:53,640 --> 01:23:56,040 DELIVER CARE. 2353 01:23:56,040 --> 01:23:57,360 AND SO IT WAS GOOD AND THEY ARE 2354 01:23:57,360 --> 01:23:59,880 ACTUALLY NOW IN THE PROCESS OF 2355 01:23:59,880 --> 01:24:03,800 DELIVERING A COMMISSION AND OUR 2356 01:24:03,800 --> 01:24:09,720 OWN REPORT THAT NIH ACTUALLY IS 2357 01:24:09,720 --> 01:24:13,200 GOING TO BE PART OF THE REPORT 2358 01:24:13,200 --> 01:24:14,760 ON GLOBAL ORAL HEALTH STATUS. 2359 01:24:14,760 --> 01:24:17,680 BUT WHAT'S VERY CHALLENGING FOR 2360 01:24:17,680 --> 01:24:19,920 NIDCR IS WE ALSO ARE STEWARDS OF 2361 01:24:19,920 --> 01:24:23,480 THE PROFESSION OF DENTISTRY. 2362 01:24:23,480 --> 01:24:25,680 BECAUSE OUR STAKEHOLDER GROUPS, 2363 01:24:25,680 --> 01:24:28,080 OUR DENTIST SCIENTIST, OUR 2364 01:24:28,080 --> 01:24:28,680 CLINICIAN SCIENTISTS, OUR PHTs 2365 01:24:28,680 --> 01:24:33,560 M COULD FROM THAT 2366 01:24:33,560 --> 01:24:35,800 PH.D.s COME FROM THAT 2367 01:24:35,800 --> 01:24:36,960 EDUCATION POOL SO WE FEEL OUR 2368 01:24:36,960 --> 01:24:38,280 MISSIONS ARE VERY INTERTWINED 2369 01:24:38,280 --> 01:24:39,600 WITH CLINICAL PRACTICE OF 2370 01:24:39,600 --> 01:24:43,080 DENTISTRY AND A ADA'S OWN POLIY 2371 01:24:43,080 --> 01:24:47,000 AND OF COURSE SUCH THAT EVERY 2372 01:24:47,000 --> 01:24:48,680 MISSION, IF SUCCEEDING, 2373 01:24:48,680 --> 01:24:49,880 STRENGTHENS THE OTHER MISSIONS. 2374 01:24:49,880 --> 01:24:52,720 THAT'S A UNIQUE CHARGE THAT OUR 2375 01:24:52,720 --> 01:24:54,360 INSTITUTE FACES. 2376 01:24:54,360 --> 01:24:56,640 MAYBE NURSING HAS THE SAME 2377 01:24:56,640 --> 01:24:57,840 RESPONSIBILITIES. 2378 01:24:57,840 --> 01:24:59,640 SO WE STRUGGLE AGAINST BIASES, 2379 01:24:59,640 --> 01:25:00,920 WE STRUGGLE THAT IN FACT ORAL 2380 01:25:00,920 --> 01:25:02,200 HEALTH IS NOT SEEN AS A CRITICAL 2381 01:25:02,200 --> 01:25:04,520 DETERMINE NAPT OF HEALTH. 2382 01:25:04,520 --> 01:25:05,280 DETERMINANT OF HEALTH AND THAT 2383 01:25:05,280 --> 01:25:06,640 EVEN PERSISTS WITHIN NIH. 2384 01:25:06,640 --> 01:25:08,480 WE HAVE PROFESSIONAL 2385 01:25:08,480 --> 01:25:09,800 ORGANIZATION AND EDUCATION UNITS 2386 01:25:09,800 --> 01:25:11,080 WHO DO NOT PRIORITIZE THE 2387 01:25:11,080 --> 01:25:12,200 IMPORTANCE OF RESEARCH BECAUSE 2388 01:25:12,200 --> 01:25:15,720 DEPTH INDUSTRY IS A VERY -- IT'S 2389 01:25:15,720 --> 01:25:17,880 A VERY LIKELIHOOD DRIVEN 2390 01:25:17,880 --> 01:25:20,160 PROFESSION AND THERE'S A LOT OF 2391 01:25:20,160 --> 01:25:23,080 EMPHASIS ON FEE FOR SERVICE AND 2392 01:25:23,080 --> 01:25:24,200 PROVIDER CODES, ET CETERA. 2393 01:25:24,200 --> 01:25:31,320 THE EVIDENCE BASE, THE ANECDOTAL 2394 01:25:31,320 --> 01:25:33,600 REVERENCES THAT WE WORRY ABOUT. 2395 01:25:33,600 --> 01:25:35,800 SOL WE HAVE TO ACTUALLY THINK OF 2396 01:25:35,800 --> 01:25:37,440 ENGAGING ALL THESE CONSTITUENTS 2397 01:25:37,440 --> 01:25:40,080 AT THE SAME TIME. 2398 01:25:40,080 --> 01:25:42,920 NOW WE ALSO HAVE OVER US A VERY 2399 01:25:42,920 --> 01:25:44,800 BIG CHALLENGE BECAUSE THE FIELD 2400 01:25:44,800 --> 01:25:48,000 OF ORAL HEALTHCARE HAS VERY, 2401 01:25:48,000 --> 01:25:50,320 VERY FEW MINORITY 2402 01:25:50,320 --> 01:25:50,920 REPRESENTATIVES SUCH THAT IT'S 2403 01:25:50,920 --> 01:25:53,240 NOT EVEN CLOSE TO REPRESENT THE 2404 01:25:53,240 --> 01:25:54,240 DEMOGRAPHICS OF THIS NATION. 2405 01:25:54,240 --> 01:25:57,400 AS YOU CAN SEE ON THE LEFT, IT'S 2406 01:25:57,400 --> 01:25:57,840 CHANGING. 2407 01:25:57,840 --> 01:25:59,920 WE HAVE THE DISEASE BURDEN THAT 2408 01:25:59,920 --> 01:26:02,160 SEEMS TO -- NOT SEEMS BUT DOES 2409 01:26:02,160 --> 01:26:03,680 AFFECT DISADVANTAGED 2410 01:26:03,680 --> 01:26:04,440 POPULATIONS, BUT WE DON'T HAVE 2411 01:26:04,440 --> 01:26:06,640 THE WORKFORCE TO ACTUALLY CARE. 2412 01:26:06,640 --> 01:26:09,120 SO WE'RE TAKING THAT VERY 2413 01:26:09,120 --> 01:26:11,080 SERIOUSLY AS NIH BUILDS ITS OWN 2414 01:26:11,080 --> 01:26:13,200 CAMPUS-WIDE INITIATIVE, UNITE, 2415 01:26:13,200 --> 01:26:16,240 ALONG WITH ALL OUR OTHER 2416 01:26:16,240 --> 01:26:16,880 PROGRAMS. 2417 01:26:16,880 --> 01:26:20,400 AND NIDCR'S OWN PORTFOLIO 2418 01:26:20,400 --> 01:26:21,040 REFLECTS THAT DEFICIENCY. 2419 01:26:21,040 --> 01:26:22,360 AND YOU CAN SEE THAT FOR EACH 2420 01:26:22,360 --> 01:26:25,360 ONE OF OUR GRANT MECHANISMS. 2421 01:26:25,360 --> 01:26:27,360 WE HAVE VERY FEW AFRICAN 2422 01:26:27,360 --> 01:26:28,720 AMERICANS, VERY FEW HISPANICS, 2423 01:26:28,720 --> 01:26:30,280 AND VERY, VERY FEW NATIVE 2424 01:26:30,280 --> 01:26:32,920 AMERICANS. 2425 01:26:32,920 --> 01:26:35,320 SO IN THINKING OF IT, KNOWING WE 2426 01:26:35,320 --> 01:26:36,480 COULDN'T DO THIS ON OUR OWN, 2427 01:26:36,480 --> 01:26:38,040 KNOWING THAT WE COULDN'T JUST 2428 01:26:38,040 --> 01:26:39,360 RELY ON UNITE TO MAKE THE 2429 01:26:39,360 --> 01:26:41,880 DIFFERENCE, WE ARE FORGING A 2430 01:26:41,880 --> 01:26:42,760 PUBLIC/PRIVATE PARTNERSHIP WITH 2431 01:26:42,760 --> 01:26:46,880 KEY ORGANIZATIONS AND REALLY 2432 01:26:46,880 --> 01:26:48,320 EVERY STAKEHOLDER GROUP TO THE 2433 01:26:48,320 --> 01:26:50,200 TABLE SO WE CAN ADDRESS MISSION 2434 01:26:50,200 --> 01:26:55,440 CRITERIA, PIPELINE DEVELOPMENT, 2435 01:26:55,440 --> 01:26:57,040 RETENTION AND NURTURING 2436 01:26:57,040 --> 01:26:58,960 INDIVIDUALS FOR THE FIELD WITH 2437 01:26:58,960 --> 01:26:59,840 SUPPORT FROM INDUSTRY WHO 2438 01:26:59,840 --> 01:27:01,000 WOULDN'T SUPPORT US DIRECTLY BUT 2439 01:27:01,000 --> 01:27:04,200 WOULD HELP IN FINANCING SCO 2440 01:27:04,200 --> 01:27:04,640 SCHOLARSHIPS. 2441 01:27:04,640 --> 01:27:09,600 DEP DENTAL EDUCATION, BY THE WS 2442 01:27:09,600 --> 01:27:11,320 VERY EXPENSIVE. 2443 01:27:11,320 --> 01:27:12,160 GRADUATING AFTER FOUR YEARS WITH 2444 01:27:12,160 --> 01:27:16,160 A DDS AND HAVING DEBTS BETWEEN 2445 01:27:16,160 --> 01:27:17,440 400 AND $500,000, DEPENDING ON 2446 01:27:17,440 --> 01:27:19,200 WHICH PART OF THE NORTHEAST 2447 01:27:19,200 --> 01:27:19,800 YOU'RE IN, SO THAT'S 2448 01:27:19,800 --> 01:27:20,280 SIGNIFICANT. 2449 01:27:20,280 --> 01:27:22,400 SO WE WERE THINKING OF ALL OF 2450 01:27:22,400 --> 01:27:24,880 THIS INDEPENDENTLY CAME THE 2451 01:27:24,880 --> 01:27:25,920 CHARGE OR THE RESPONSIBILITY FOR 2452 01:27:25,920 --> 01:27:28,400 ME TO CONTINUE DEVELOPING OUR 2453 01:27:28,400 --> 01:27:30,520 STRATEGIC PLAN THAT MARTHA 2454 01:27:30,520 --> 01:27:32,440 SOMERMAN HAD INITIATED. 2455 01:27:32,440 --> 01:27:35,240 AND IT WAS HARD TO DO THAT BY 2456 01:27:35,240 --> 01:27:39,040 JUST CONDITIONING ON THAT PATH 2457 01:27:39,040 --> 01:27:41,640 JUST CONTINUING ON THAT PATH, 2458 01:27:41,640 --> 01:27:42,840 THE PANDEMIC CHANGED OUR WORLD. 2459 01:27:42,840 --> 01:27:44,080 WE HAD TO THINK OF TRANSLATION, 2460 01:27:44,080 --> 01:27:45,600 WE HAD TO THINK OF DIVERSIFYING 2461 01:27:45,600 --> 01:27:49,240 AND USING METRICS TO MEASURE THE 2462 01:27:49,240 --> 01:27:50,400 OUTCOMES. 2463 01:27:50,400 --> 01:27:52,880 SO I WAS VERY DISEASE-AGNOSTIC, 2464 01:27:52,880 --> 01:27:53,880 EVEN THOUGH I HAVE MY INTEREST 2465 01:27:53,880 --> 01:27:55,520 AREA, I DECIDED NOT TO BE 2466 01:27:55,520 --> 01:27:56,720 FOCUSED ON ONE DISEASE OR THE 2467 01:27:56,720 --> 01:27:58,720 OTHER, BUT TO THINK OF THE 2468 01:27:58,720 --> 01:28:00,520 OVERARCHING THEMES OF 2469 01:28:00,520 --> 01:28:04,600 TRANSLATION DIVERSE FIGHTING D 2470 01:28:04,600 --> 01:28:06,080 OUTCOME ASSESSMENTS. 2471 01:28:06,080 --> 01:28:10,000 WE THIS HAD THESE FIVE VERY C 2472 01:28:10,000 --> 01:28:12,200 GOALS, STRESSING TRANSLATION 2473 01:28:12,200 --> 01:28:13,200 RESEARCH INVOLVES ALL OF THESE 2474 01:28:13,200 --> 01:28:14,320 DOMAINS OF RESEARCH, THERE'S NOT 2475 01:28:14,320 --> 01:28:15,560 ONE THAT STANDS OUT AND IS MORE 2476 01:28:15,560 --> 01:28:17,120 IMPORTANT THAN THE OTHER. 2477 01:28:17,120 --> 01:28:18,440 BECAUSE ENGAGING WITH THE 2478 01:28:18,440 --> 01:28:20,400 COMMUNITY NORMALLY GIVES RISE TO 2479 01:28:20,400 --> 01:28:21,720 A FINDING OR OBSERVATION THAT 2480 01:28:21,720 --> 01:28:24,320 CAN BE TESTED IN A 2481 01:28:24,320 --> 01:28:25,760 HYPOTHESIS-DRIVEN WAY. 2482 01:28:25,760 --> 01:28:28,480 SO IN THE PAST WE WOULD THINK 2483 01:28:28,480 --> 01:28:30,960 BASIC ON ONE END, CLINICAL ON 2484 01:28:30,960 --> 01:28:32,880 THE OTHER AND TRANSLATION IN THE 2485 01:28:32,880 --> 01:28:34,440 MIDDLE, VERY LINEAR, BUT IT 2486 01:28:34,440 --> 01:28:35,720 REALLY IS A CIRCULAR CONTINUUM 2487 01:28:35,720 --> 01:28:37,480 AND I WANTED TO EMPHASIZE THAT 2488 01:28:37,480 --> 01:28:39,920 OBVIOUS LIP FOR THIS GROUP. 2489 01:28:39,920 --> 01:28:41,520 OBVIOUSLY FOR THIS GROUP. 2490 01:28:41,520 --> 01:28:42,960 THE FIRST PRIORITY IS TO REALLY 2491 01:28:42,960 --> 01:28:46,880 PUT MEAT ON THE BONES, TO 2492 01:28:46,880 --> 01:28:48,080 ACTUALLY FIND THE UNDERPINNINGS 2493 01:28:48,080 --> 01:28:49,400 OF WHAT THAT MEANS. 2494 01:28:49,400 --> 01:28:51,360 UNIQUENESS AND SHARED PROPERTIES 2495 01:28:51,360 --> 01:28:54,120 OR QUALITIES OF PROGRESS OF THE 2496 01:28:54,120 --> 01:28:54,440 DISEASE. 2497 01:28:54,440 --> 01:28:55,640 THEN TAKE THAT INFORMATION AND 2498 01:28:55,640 --> 01:28:58,360 DRAW FROM ALL OF US AND THESE 2499 01:28:58,360 --> 01:29:01,760 AMAZING PROGRAMS THAT EXIST TO 2500 01:29:01,760 --> 01:29:03,280 COME UP WITH INDIVIDUALIZED 2501 01:29:03,280 --> 01:29:04,360 APPROACHES FOR PERSONALIZED 2502 01:29:04,360 --> 01:29:06,920 DENTAL MEDICINE, TRANSLATING IN 2503 01:29:06,920 --> 01:29:08,440 IMPLEMENTATION SCIENCES IS SO 2504 01:29:08,440 --> 01:29:10,200 IMPORTANT FOR OUR COMMUNITY AS 2505 01:29:10,200 --> 01:29:12,360 IS NURTURING THE DIVERSE NEW 2506 01:29:12,360 --> 01:29:14,240 GENERATION AND EXPANDING OUR 2507 01:29:14,240 --> 01:29:15,440 PARTNERSHIPS, INCLUDING THOSE 2508 01:29:15,440 --> 01:29:18,200 WITH OTHER INSTITUTES. 2509 01:29:18,200 --> 01:29:19,720 SO IF YOU LOOKED AT THE 2510 01:29:19,720 --> 01:29:20,600 EXTRAMURAL PROGRAM AND MOST OF 2511 01:29:20,600 --> 01:29:22,920 OUR FUNDING GOES OVER 2512 01:29:22,920 --> 01:29:26,440 $350 MILLION OF OUR BUDGET IS 2513 01:29:26,440 --> 01:29:28,200 SPENT ON THE EXTRAMURAL 2514 01:29:28,200 --> 01:29:28,640 COMMUNITY. 2515 01:29:28,640 --> 01:29:31,240 WE FUND PRACTICALLY EVERY AREA 2516 01:29:31,240 --> 01:29:31,680 OF SCIENCE. 2517 01:29:31,680 --> 01:29:33,560 THE ONES ON THE FAR RIGHT ARE 2518 01:29:33,560 --> 01:29:35,200 ONES WE'RE PUTTING EXTRA 2519 01:29:35,200 --> 01:29:37,080 EMPHASIS ON, BUT REALLY THERE'S 2520 01:29:37,080 --> 01:29:38,160 SOMETHING HERE FOR EVERYONE. 2521 01:29:38,160 --> 01:29:39,480 YOU CAN GO THROUGH THE LIST AND 2522 01:29:39,480 --> 01:29:40,440 THERE ARE CERTAINLY 2523 01:29:40,440 --> 01:29:41,120 OPPORTUNITIES FOR COLLABORATION 2524 01:29:41,120 --> 01:29:42,520 IN EACH OF THESE DOMAINS, 2525 01:29:42,520 --> 01:29:43,320 WHETHER IT'S DISEASE OR 2526 01:29:43,320 --> 01:29:46,360 DISCIPLINE. 2527 01:29:46,360 --> 01:29:48,760 LILLIAN SHUM IS REALLY AN EXPERT 2528 01:29:48,760 --> 01:29:51,160 DIRECTOR OF OUR PROGRAM. 2529 01:29:51,160 --> 01:29:53,160 WE HAVE BUILT UP OUR TRAINING 2530 01:29:53,160 --> 01:29:54,680 PROGRAM SO WE ADDRESS ALL THE 2531 01:29:54,680 --> 01:29:57,960 LEAKS IN THE PIPELINE, WHICH AS 2532 01:29:57,960 --> 01:29:59,600 I'VE MENTIONED BEFORE IS NARROW 2533 01:29:59,600 --> 01:30:02,000 AND NOT YIELDING OF THE CRITICAL 2534 01:30:02,000 --> 01:30:04,200 MASS THAT WE NEED AS AN 2535 01:30:04,200 --> 01:30:06,280 INSTITUTE AND AS A PROFESSION TO 2536 01:30:06,280 --> 01:30:08,880 FORGE SCIENCE FORWARD. 2537 01:30:08,880 --> 01:30:10,120 BUT WE'RE TRYING VERY HARD, AND 2538 01:30:10,120 --> 01:30:11,520 WHAT YOU SEE IN THE PINK OR RED 2539 01:30:11,520 --> 01:30:13,400 BOXES IS WHAT THE INTRAMURAL 2540 01:30:13,400 --> 01:30:16,320 PROGRAM OFFERS, AND EXTRAMURAL 2541 01:30:16,320 --> 01:30:17,240 PROGRAMS HAVE THESE AND ALL OF 2542 01:30:17,240 --> 01:30:22,440 THESE TERMS ARE VERY FAMILIAR TO 2543 01:30:22,440 --> 01:30:22,600 YOU. 2544 01:30:22,600 --> 01:30:25,640 WE'VE REALLY ADDED ON A HUGE 2545 01:30:25,640 --> 01:30:26,520 MOUNT OF DIVERSITY SUPPLEMENTS 2546 01:30:26,520 --> 01:30:28,800 AND MECHANISMS TO ENCOURAGE AS 2547 01:30:28,800 --> 01:30:31,000 EARLY AS POSSIBLE A PIPELINE 2548 01:30:31,000 --> 01:30:32,560 DEVELOPMENT THROUGH CEPA, WHICH 2549 01:30:32,560 --> 01:30:38,040 IS N IGMS'S PROGRAM, SO WE'VE 2550 01:30:38,040 --> 01:30:39,760 DOVETAILED TO ACTUALLY MOVE THE 2551 01:30:39,760 --> 01:30:40,280 NEEDLE IN THIS AREA. 2552 01:30:40,280 --> 01:30:43,160 YOU KNOW, WHEN I CAME ON BOARD, 2553 01:30:43,160 --> 01:30:43,880 THE PUBLIC HEALTH RESIDENCY 2554 01:30:43,880 --> 01:30:45,480 PROGRAM THAT HAD EXISTED FOR 2555 01:30:45,480 --> 01:30:47,000 YEARS WAS ACTUALLY SLATED FOR 2556 01:30:47,000 --> 01:30:47,240 CLOSURE. 2557 01:30:47,240 --> 01:30:49,520 IT WAS, IN FACT, SHUT DOWN. 2558 01:30:49,520 --> 01:30:51,720 BUT THE PANDEMIC SHOWED US THAT 2559 01:30:51,720 --> 01:30:53,560 THERE WAS A NEED FOR THIS IN OUR 2560 01:30:53,560 --> 01:30:55,760 PROFESSION AS IT WOULD BE FOR 2561 01:30:55,760 --> 01:30:58,640 THE GENERAL FIELD, RIGHT, PUBLIC 2562 01:30:58,640 --> 01:31:00,760 HEALTH WAS ALWAYS SEEN AS A 2563 01:31:00,760 --> 01:31:02,360 SIDELINE THING, BUT NOW I THINK 2564 01:31:02,360 --> 01:31:04,000 EVERYONE GETS IT, THAT IT IS 2565 01:31:04,000 --> 01:31:05,840 ACTUALLY IMPORTANT FOR US TO 2566 01:31:05,840 --> 01:31:08,640 HAVE A MOBILIZABLE UNIT OF -- 2567 01:31:08,640 --> 01:31:09,880 UNITS ALL OVER THE COUNTRY THAT 2568 01:31:09,880 --> 01:31:15,680 CAN ACTUALLY ENGAGE AND MITIGATE 2569 01:31:15,680 --> 01:31:16,680 PANDEMIC OR ANYTHING LIKE THAT. 2570 01:31:16,680 --> 01:31:18,520 SO WE ARE NOW LAUNCHING A 2571 01:31:18,520 --> 01:31:20,040 THREE-YEAR PROGRAM A LITTLE 2572 01:31:20,040 --> 01:31:20,920 DIFFERENT, IT USED TO BE JUST 2573 01:31:20,920 --> 01:31:22,920 ONE YEAR, WE'RE ADDING ON A 2574 01:31:22,920 --> 01:31:24,200 TWO-YEAR POSTDOC EXPERIENCE, SO 2575 01:31:24,200 --> 01:31:27,600 THAT OUR FELLOWS IN TRAINING WHO 2576 01:31:27,600 --> 01:31:30,280 ARE TYPICALLY DDAs WITH MPHs 2577 01:31:30,280 --> 01:31:37,440 CAN AUTOIMMUNE TACH TO T 2578 01:31:37,440 --> 01:31:38,560 HAS INTEREST IN ORAL CANCERS. 2579 01:31:38,560 --> 01:31:41,720 SO THAT WOULD BE A GREAT CANCER. 2580 01:31:41,720 --> 01:31:42,240 PROJECT. 2581 01:31:42,240 --> 01:31:46,880 WE HAVE NATIONAL INSTITUTE OF 2582 01:31:46,880 --> 01:31:49,600 AGING, COGNITIVE DECLINE, SO 2583 01:31:49,600 --> 01:31:51,320 WITH AT LEAST TWO OR THREE 2584 01:31:51,320 --> 01:31:52,120 TRAINEES A YEAR, WE CAN MAKE A 2585 01:31:52,120 --> 01:31:54,200 LITTLE BIT OF A DENT IN 2586 01:31:54,200 --> 01:31:56,920 PRODUCING A PUBLIC HEALTH -- 2587 01:31:56,920 --> 01:31:58,120 PUBLIC HEALTH DENTISTS WHO ARE 2588 01:31:58,120 --> 01:32:00,520 WELL INFORMED, WHO ARE KNOWLEDGE 2589 01:32:00,520 --> 01:32:06,480 CREATE TORES, NOT 2590 01:32:06,480 --> 01:32:07,800 KREE CREATORS. 2591 01:32:07,800 --> 01:32:11,400 WE OFFER A TWO YEAR RESEARCH IF 2592 01:32:11,400 --> 01:32:12,240 FELLOWSHIP WHERE THEY ACTUALLY 2593 01:32:12,240 --> 01:32:15,520 LOOK AT WHERE AN UNDIAGNOSED 2594 01:32:15,520 --> 01:32:18,680 CONDITION, I'LL GIVE YOU 2595 01:32:18,680 --> 01:32:19,880 EXAMPLES OF THE SEARCH GOING ON 2596 01:32:19,880 --> 01:32:21,000 THERE, VERY NICE PROGRAM THAT 2597 01:32:21,000 --> 01:32:22,640 HAS GROWN IN ITS NATIONAL 2598 01:32:22,640 --> 01:32:25,920 STATURE LED BY JANICE LI, WHO 2599 01:32:25,920 --> 01:32:27,040 YOU SEE HERE ON THE RIGHT. 2600 01:32:27,040 --> 01:32:29,200 YOU KNOW, I THINK IF I LOOKED AT 2601 01:32:29,200 --> 01:32:31,200 THE BLESSINGS THAT WE HAVE 2602 01:32:31,200 --> 01:32:34,040 ACCUMULATED OVER THESE 75 YEARS, 2603 01:32:34,040 --> 01:32:35,200 OUR INTRAMURAL PROGRAM STANDS 2604 01:32:35,200 --> 01:32:36,560 OUT BECAUSE WE HAVE THE MOST 2605 01:32:36,560 --> 01:32:37,760 OUTSTANDING GROUP OF 2606 01:32:37,760 --> 01:32:39,120 INVESTIGATORS WHO ARE CUTTING 2607 01:32:39,120 --> 01:32:41,600 EDGE SCIENTISTS, VERY SERIOUS 2608 01:32:41,600 --> 01:32:43,920 ABOUT WHAT THEY DO, AND WE'RE 2609 01:32:43,920 --> 01:32:47,520 GROWING TO WHERE 7 OUT OF THE 2610 01:32:47,520 --> 01:32:51,480 26 -- SORRY -- ACTUALLY ARE 2611 01:32:51,480 --> 01:32:52,160 CLINICIAN SCIENTISTS, AND THEY 2612 01:32:52,160 --> 01:32:53,640 WORK IN BUILDING 10 PRIMARILY, 2613 01:32:53,640 --> 01:32:55,320 AND SOME OF THEM ARE SCATTERED 2614 01:32:55,320 --> 01:32:56,080 ACROSS CAMPUS. 2615 01:32:56,080 --> 01:32:58,280 AND THE FOCUS IS IN THESE AREAS. 2616 01:32:58,280 --> 01:33:00,040 THERE'S A HUGE SECTION ON 2617 01:33:00,040 --> 01:33:03,080 SKELETAL MATRIX AND 2618 01:33:03,080 --> 01:33:03,440 MECHANO-BIOLOGY. 2619 01:33:03,440 --> 01:33:04,920 THESE ARE THE PIs HERE. 2620 01:33:04,920 --> 01:33:06,240 IT'S GREAT BECAUSE THEY ACTUALLY 2621 01:33:06,240 --> 01:33:09,120 SEE PATIENTS AND THEY'RE TESTING 2622 01:33:09,120 --> 01:33:11,040 VARIOUS INTERVENTIONS AND 2623 01:33:11,040 --> 01:33:12,400 PHARMACOLOGICAL INTERVENTIONS 2624 01:33:12,400 --> 01:33:13,600 ACTUALLY FOR VERY RARE AND 2625 01:33:13,600 --> 01:33:16,800 UNDIAGNOSED CONDITIONS. 2626 01:33:16,800 --> 01:33:18,160 YOU CAN SEE THAT RIGHT HERE IN 2627 01:33:18,160 --> 01:33:19,520 THE CENTER OF OUR CAMPUS. 2628 01:33:19,520 --> 01:33:21,480 WE HAVE A SJOGREN'S CENTER THAT 2629 01:33:21,480 --> 01:33:23,040 ACTUALLY DIAGNOSES AND TREATS 2630 01:33:23,040 --> 01:33:25,480 PATIENTS LED BY BLAKE WARNER AND 2631 01:33:25,480 --> 01:33:26,640 HIS TEAM. 2632 01:33:26,640 --> 01:33:28,920 SO THAT'S A BLESSING TO HAVE 2633 01:33:28,920 --> 01:33:30,680 THAT AVAILABLE, AND WE DO HAVE 2634 01:33:30,680 --> 01:33:31,800 REFERRALS FROM ALL OVER THE 2635 01:33:31,800 --> 01:33:33,440 WORLD ACTUALLY AND HAVE A 2636 01:33:33,440 --> 01:33:36,080 PATIENT REPOSITORY. 2637 01:33:36,080 --> 01:33:37,520 ABOUT 4,000 CASES OF SJOGREN'S, 2638 01:33:37,520 --> 01:33:38,360 WHERE WE'VE COLLECTED SAMPLES 2639 01:33:38,360 --> 01:33:40,240 AND HAVE KIND OF A LARGE 2640 01:33:40,240 --> 01:33:42,520 BIOREPOSITORY TO MOVE FORWARD. 2641 01:33:42,520 --> 01:33:44,160 I BROUGHT THIS UP AS JACKIE'S 2642 01:33:44,160 --> 01:33:47,200 PROJECT LOOKING AT 2643 01:33:47,200 --> 01:33:47,760 GRAFT-VERSUS-HOST DISEASE 2644 01:33:47,760 --> 01:33:49,400 BECAUSE THERE ARE LOTS OF ORAL 2645 01:33:49,400 --> 01:33:50,720 MANIFESTATIONS AND JACKIE IS 2646 01:33:50,720 --> 01:33:51,920 ACTUALLY LOOKING AT AN 2647 01:33:51,920 --> 01:33:53,040 INTERVENTION THAT'S PROVEN TO BE 2648 01:33:53,040 --> 01:33:53,600 QUITE SUCCESSFUL. 2649 01:33:53,600 --> 01:33:58,360 AS YOU CAN SEE THE SEVERE 2650 01:33:58,360 --> 01:34:00,520 REACTIONS IN GRAFT-VERSUS-HOST 2651 01:34:00,520 --> 01:34:01,480 DISEASE AFFECTS SO MANY TISSUES 2652 01:34:01,480 --> 01:34:06,160 IN THE ORAL CAVITY, SCLEROSIS, 2653 01:34:06,160 --> 01:34:07,680 HYPERKERATOSIS AND LOTS OF OTHER 2654 01:34:07,680 --> 01:34:09,320 LESIONS THAT AFFECT SALIVARY 2655 01:34:09,320 --> 01:34:13,360 GLAND FUNCTION AND OTHER BODY 2656 01:34:13,360 --> 01:34:16,320 FUNCTIONS. 2657 01:34:16,320 --> 01:34:18,800 INTERESTING FOR MY INTRAMURAL 2658 01:34:18,800 --> 01:34:21,560 WORLD AND FIBROSIS IS THIS FAC 2659 01:34:21,560 --> 01:34:22,840 INHIBITOR THAT'S ACTUALLY BEING 2660 01:34:22,840 --> 01:34:24,200 USED TO PREVENT SCAR TISSUE 2661 01:34:24,200 --> 01:34:24,880 FORMATION. 2662 01:34:24,880 --> 01:34:26,240 JUST THOUGHT I WOULD BRING THAT 2663 01:34:26,240 --> 01:34:30,080 UP AS AN OPPORTUNITY FOR NCCIH 2664 01:34:30,080 --> 01:34:32,920 AND US TO COLLABORATE ON SPINOFF 2665 01:34:32,920 --> 01:34:34,880 STUDIES THAT WOULD COME FROM 2666 01:34:34,880 --> 01:34:36,640 WOUND HEALING, AND BEING ABLE TO 2667 01:34:36,640 --> 01:34:40,600 CONTROL EXCESSIVE FIBROBLAST 2668 01:34:40,600 --> 01:34:41,480 FUNCTION REALLY. 2669 01:34:41,480 --> 01:34:43,000 IF THERE'S NOT ENOUGH 2670 01:34:43,000 --> 01:34:47,160 REMODELING, THAT'S WHAT IT IS. 2671 01:34:47,160 --> 01:34:49,200 SO LIKE EVERY OTHER INSTITUTE, 2672 01:34:49,200 --> 01:34:52,200 WE ON A SMALLER SCALE INVEST IN 2673 01:34:52,200 --> 01:34:53,280 LARGER INITIATIVES ACROSS THE 2674 01:34:53,280 --> 01:34:53,600 COUNTRY. 2675 01:34:53,600 --> 01:34:54,800 THESE COST A LITTLE BIT MORE. 2676 01:34:54,800 --> 01:34:56,240 AND WE HAVE THREE OF THEM THAT 2677 01:34:56,240 --> 01:34:58,200 HAVE BEEN RUNNING FOR YEARS NOW 2678 01:34:58,200 --> 01:34:59,960 INTO THEIR SECOND AND THIRD 2679 01:34:59,960 --> 01:35:00,960 CYCLES, AND I'M GOING TO 2680 01:35:00,960 --> 01:35:03,400 DESCRIBE THEM VERY BRIEFLY. 2681 01:35:03,400 --> 01:35:05,280 THE NATIONAL PRACTICE-BASED 2682 01:35:05,280 --> 01:35:06,800 NETWORK, THE REGENERATIVE 2683 01:35:06,800 --> 01:35:08,400 MEDICINE ONE THAT MARTHA WAS 2684 01:35:08,400 --> 01:35:11,360 VERY INSTRUMENTAL IN SETTING UP, 2685 01:35:11,360 --> 01:35:13,560 FACEBASE, WHICH IS A REPOSITORY 2686 01:35:13,560 --> 01:35:15,720 OF GENOMIC INFORMATION AND 2687 01:35:15,720 --> 01:35:16,640 PHENOTYPE INFORMATION ON 2688 01:35:16,640 --> 01:35:18,040 CRANIOFACIAL DISORDERS, AND THEN 2689 01:35:18,040 --> 01:35:20,800 WHAT'S COMING UP VERY SOON IS 2690 01:35:20,800 --> 01:35:21,880 THE TEMPOROMANDIBULAR JOINT OR 2691 01:35:21,880 --> 01:35:23,400 DYSFUNCTION CENTER. 2692 01:35:23,400 --> 01:35:26,560 SO IN THIS PARTICULAR EFFORT OF 2693 01:35:26,560 --> 01:35:27,800 CREATING A NETWORK ACROSS THE 2694 01:35:27,800 --> 01:35:30,040 COUNTRY OF PRACTITIONERS WHO ARE 2695 01:35:30,040 --> 01:35:31,280 CALIBRATED AND TRAINED TO 2696 01:35:31,280 --> 01:35:33,240 ACTUALLY ANSWER QUESTIONS THAT 2697 01:35:33,240 --> 01:35:35,200 ARE COMMON CLINICAL QUESTIONS, 2698 01:35:35,200 --> 01:35:36,440 EVERYDAY PROBLEMS THAT DENTISTS 2699 01:35:36,440 --> 01:35:38,760 AND ORAL HEALTH PROFESSIONALS, 2700 01:35:38,760 --> 01:35:41,280 AND THEY'VE GOT A GOOD BASE OF 2701 01:35:41,280 --> 01:35:42,320 7,000 PRACTITIONERS, AND THEY'RE 2702 01:35:42,320 --> 01:35:45,720 GOING TO BE MORPHED BECAUSE THE 2703 01:35:45,720 --> 01:35:46,920 PANDEMIC TAUGHT US THEY OUGHT TO 2704 01:35:46,920 --> 01:35:48,280 BE CONNECTING THIS AND BE READY 2705 01:35:48,280 --> 01:35:50,120 TO ACTIVATE THIS GROUP TO LOOK 2706 01:35:50,120 --> 01:35:52,080 AT OPERATORY CONDITIONS AND 2707 01:35:52,080 --> 01:35:53,840 THINGS THREATENING TO THE 2708 01:35:53,840 --> 01:35:54,760 PRACTICE OF DENTISTRY. 2709 01:35:54,760 --> 01:35:56,160 SO THIS IS IN THE PROCESS OF 2710 01:35:56,160 --> 01:35:58,600 ACTUALLY SHAPING UP TO BE MUCH 2711 01:35:58,600 --> 01:35:59,880 MORE DIVERSE AND INCLUSIVE. 2712 01:35:59,880 --> 01:36:02,760 BUT WHAT'S INTERESTING IS, WE'RE 2713 01:36:02,760 --> 01:36:05,600 GOING TO START UP A PRACTICE 2714 01:36:05,600 --> 01:36:08,040 BASED RESEARCH -- WITHIN DENTAL 2715 01:36:08,040 --> 01:36:09,760 SCHOOLS BECAUSE SCHOOLS ARE 2716 01:36:09,760 --> 01:36:11,480 SAFETY NET PROVIDERS AND SEE THE 2717 01:36:11,480 --> 01:36:13,120 ENTIRE SPECTRUM OF PATIENTS FROM 2718 01:36:13,120 --> 01:36:14,240 VERY SIMPLE TO VERY COMPLEX TO 2719 01:36:14,240 --> 01:36:16,640 THE MEDICALLY COMPROMISED AND 2720 01:36:16,640 --> 01:36:18,200 SPECIAL NEEDS PATIENTS. 2721 01:36:18,200 --> 01:36:20,160 THAT REQUIRE VERY SPECIAL CARE 2722 01:36:20,160 --> 01:36:21,360 AS YOU KNOW. 2723 01:36:21,360 --> 01:36:23,960 SOMEONE WITH SPINA BIFIDA OR 2724 01:36:23,960 --> 01:36:24,960 MULTIPLE SCLEROSIS, THEY DON'T 2725 01:36:24,960 --> 01:36:27,480 HAVE A DENTIST THAT HAVE THE 2726 01:36:27,480 --> 01:36:29,040 OPERATORIES AND EVEN ARE TRAINED 2727 01:36:29,040 --> 01:36:31,240 FOR SPECIAL NEEDS PATIENTS, AND 2728 01:36:31,240 --> 01:36:33,840 SO WE'RE GOING TO SET THIS UP 2729 01:36:33,840 --> 01:36:36,040 WITHIN SCHOOLS TO ENGAGE 2730 01:36:36,040 --> 01:36:38,240 CLINICIANS AND FACULTY, 2731 01:36:38,240 --> 01:36:38,880 ADMINISTRATORS AS WELL AS 2732 01:36:38,880 --> 01:36:42,520 PATIENTS AND CREATING THIS SENSE 2733 01:36:42,520 --> 01:36:46,880 OF CURIOSITY AND DRIVE TO 2734 01:36:46,880 --> 01:36:47,880 ACTUALLY CREATING KNOWLEDGE 2735 01:36:47,880 --> 01:36:49,480 CHAIRSIDE THAT THEY CAN TAKE 2736 01:36:49,480 --> 01:36:50,840 THEN INTO THEIR PRACTICE 2737 01:36:50,840 --> 01:36:52,040 EXPERIENCES OR WHEN THEY COME 2738 01:36:52,040 --> 01:36:54,440 BACK AS FACULTY. 2739 01:36:54,440 --> 01:36:56,200 THE REGENERATIVE MEDICINE 2740 01:36:56,200 --> 01:36:57,280 CONSORTIUM WHICH IS BASED IN 2741 01:36:57,280 --> 01:36:58,680 CALIFORNIA, WE HAVE TWO GROUPS 2742 01:36:58,680 --> 01:37:01,920 AND THE MICHIGAN HARVARD 2743 01:37:01,920 --> 01:37:03,160 PITTSBURGH ONE, NORTHEAST, SO TO 2744 01:37:03,160 --> 01:37:06,600 SPEAK, IS DOING VERY WELL. 2745 01:37:06,600 --> 01:37:07,520 THERE'S MANY FDA PRODUCTS RIGHT 2746 01:37:07,520 --> 01:37:08,880 NOW THAT ARE IN THE PROCESS OF 2747 01:37:08,880 --> 01:37:11,280 BEING APPROVED, AND THEY DEAL 2748 01:37:11,280 --> 01:37:14,440 WITH VARIOUS ASPECTS OF 2749 01:37:14,440 --> 01:37:15,440 PERIODONTAL DISEASE AND FRACTURE 2750 01:37:15,440 --> 01:37:19,080 HEALING AND DIFFERENT KINDS OF 2751 01:37:19,080 --> 01:37:21,280 REGENERATIVE -- SO THAT'S 2752 01:37:21,280 --> 01:37:24,200 ACTUALLY BEEN A HIGHLY 2753 01:37:24,200 --> 01:37:25,080 SUCCESSFUL INFRASTRUCTURE AND 2754 01:37:25,080 --> 01:37:26,360 CAPACITY BUILDING CONSORTIUM. 2755 01:37:26,360 --> 01:37:27,600 VERY PLEASED WITH IT. 2756 01:37:27,600 --> 01:37:29,000 FINALLY THE FACEBASE, A PROGRAM 2757 01:37:29,000 --> 01:37:31,520 THAT I TALKED ABOUT, HAS 2758 01:37:31,520 --> 01:37:34,920 GATHERED QUITE A REPOSITORY OF 2759 01:37:34,920 --> 01:37:38,400 GENOMIC INFORMATION AND -- IN 2760 01:37:38,400 --> 01:37:39,600 THIS DATABASE THAT IS ACCESSIBLE 2761 01:37:39,600 --> 01:37:40,960 TO ALL, AND THEY'RE HOPING THAT 2762 01:37:40,960 --> 01:37:44,680 THE DATA SCIENCE INITIATIVE, NIH 2763 01:37:44,680 --> 01:37:46,080 IS ACTUALLY INVESTING IN IT NOW, 2764 01:37:46,080 --> 01:37:47,720 THAT WE CAN ACTUALLY MAKE ALL OF 2765 01:37:47,720 --> 01:37:49,120 THIS TRANSFERABLE AND 2766 01:37:49,120 --> 01:37:50,040 INTERRELATABLE, BECAUSE THAT IS 2767 01:37:50,040 --> 01:37:50,640 THE CHALLENGE. 2768 01:37:50,640 --> 01:37:54,920 YOU CAN SEE THAT IT'S ACROSS 2769 01:37:54,920 --> 01:37:55,920 EVOLUTION WITH DIFFERENT MODEL 2770 01:37:55,920 --> 01:37:57,000 SYSTEMS AND MAKING A DIFFERENCE 2771 01:37:57,000 --> 01:37:57,560 TO PATIENTS. 2772 01:37:57,560 --> 01:38:01,160 AND THIS IS WHAT I MEAN BY 2773 01:38:01,160 --> 01:38:01,720 CRANIOFACIAL DISORDERS. 2774 01:38:01,720 --> 01:38:03,800 SO HERE IS A CHILD THAT HAS 2775 01:38:03,800 --> 01:38:06,760 CLEFT, CORRECTED SURGICALLY, 2776 01:38:06,760 --> 01:38:08,760 CHILD IS ABOUT 6 MONTHS OLD, 2777 01:38:08,760 --> 01:38:10,160 COMES BACK IN FOR SECOND 2778 01:38:10,160 --> 01:38:10,560 INTERVENTION. 2779 01:38:10,560 --> 01:38:12,000 THE MID FACE IS GROWING AT THAT 2780 01:38:12,000 --> 01:38:13,200 TIME SO THERE'S ALWAYS A MID 2781 01:38:13,200 --> 01:38:15,080 FACE KIND OF DEPRESSION BECAUSE 2782 01:38:15,080 --> 01:38:16,920 YOU'RE BRINGING ABOUT CLOSURE 2783 01:38:16,920 --> 01:38:19,440 BEFORE THAT ACTUALLY HAPPENS. 2784 01:38:19,440 --> 01:38:20,440 IN AN UNNATURAL WAY. 2785 01:38:20,440 --> 01:38:23,280 AND THAT CHILD UNDERGOES A 2786 01:38:23,280 --> 01:38:25,800 SERIES OF CARE -- 2787 01:38:25,800 --> 01:38:26,760 MULTIDISCIPLINARY CARE 2788 01:38:26,760 --> 01:38:27,120 THROUGHOUT LIFE. 2789 01:38:27,120 --> 01:38:31,040 WHEN YOU LOOK AT HIM, GOD BLESS 2790 01:38:31,040 --> 01:38:32,480 HIM, HE ACTUALLY PASSED HIM AWAY 2791 01:38:32,480 --> 01:38:34,200 BUT I TREATED HIM WHEN HE WAS IN 2792 01:38:34,200 --> 01:38:36,080 AFRICA, HE HAD SURGERY THAT 2793 01:38:36,080 --> 01:38:37,360 INVOLVED REPLACING HIS -- REALLY 2794 01:38:37,360 --> 01:38:39,160 RESHAPING HIS SKULL AND HIS 2795 01:38:39,160 --> 01:38:39,360 BRAIN. 2796 01:38:39,360 --> 01:38:40,960 LOOK AT THE EFFECTS ON HIS 2797 01:38:40,960 --> 01:38:44,600 ORBITS AND ALL THE SEQUELAE OF 2798 01:38:44,600 --> 01:38:46,040 THAT SURGERY THAT HE HAD TO DEAL 2799 01:38:46,040 --> 01:38:50,080 WITH AND THE SAME WITH PUZANS. 2800 01:38:50,080 --> 01:38:51,400 SO WE HAVE A NEED TO BE LOOKING 2801 01:38:51,400 --> 01:38:52,480 AT THAT GROUP OF PATIENTS AND 2802 01:38:52,480 --> 01:38:53,880 THEN TAKING ADVANTAGE OF THIS 2803 01:38:53,880 --> 01:38:55,880 DATABASE TO SEE HOW BEST WE CAN 2804 01:38:55,880 --> 01:38:59,160 TRANSFER THIS TO MAKE IT REALLY 2805 01:38:59,160 --> 01:39:00,040 USER-FRIENDLY FOR CLINICIANS WHO 2806 01:39:00,040 --> 01:39:03,280 HAVE A HARD TIME DIFFERENTIATING 2807 01:39:03,280 --> 01:39:04,720 BECAUSE THESE SYMPTOMS -- 2808 01:39:04,720 --> 01:39:06,800 SYNDROMIC CONDITIONS ARE VERY 2809 01:39:06,800 --> 01:39:08,440 SUBTLE SOMETIMES AND CAN BE 2810 01:39:08,440 --> 01:39:08,760 MISSED. 2811 01:39:08,760 --> 01:39:10,960 VERY OFTEN THE DENTAL PHENOTYPE 2812 01:39:10,960 --> 01:39:15,360 IS NOT TAKEN AS SERIOUSLY. 2813 01:39:15,360 --> 01:39:19,280 SO AS I LOOKED AT THE MOVING 2814 01:39:19,280 --> 01:39:22,200 FRONTS AND HPV RISING EVEN WITH 2815 01:39:22,200 --> 01:39:23,120 THE VACCINES THAT ARE EFFECTIVE, 2816 01:39:23,120 --> 01:39:24,960 THAT IT'S RISING TO WHERE MALES 2817 01:39:24,960 --> 01:39:27,480 ARE GETTING FAR MORE AFFECTED 2818 01:39:27,480 --> 01:39:27,920 THAN FEMALES. 2819 01:39:27,920 --> 01:39:29,040 INITIALLY THE VACCINE WAS 2820 01:39:29,040 --> 01:39:30,840 AVAILABLE FOR TEENAGE GIRLS, IF 2821 01:39:30,840 --> 01:39:32,280 YOU REMEMBER. 2822 01:39:32,280 --> 01:39:34,400 WELL, NOW IT'S SEEMING TO BE 2823 01:39:34,400 --> 01:39:36,760 THAT YOUNG MALES ARE AFFECTED 2824 01:39:36,760 --> 01:39:38,560 FIVE OR SIX FOLD TIMES MORE. 2825 01:39:38,560 --> 01:39:41,160 SO WE BROUGHT TOGETHER A THINK 2826 01:39:41,160 --> 01:39:42,360 TANK, NED SHARPLESS WAS ON BOARD 2827 01:39:42,360 --> 01:39:44,760 TO LOOK AT HOW WE CAN ADVANCE 2828 01:39:44,760 --> 01:39:46,640 EARLY DIAGNOSIS, AND YOU KNOW 2829 01:39:46,640 --> 01:39:49,280 THAT WITH NCCIH, THAT THE 2830 01:39:49,280 --> 01:39:51,360 EMPHASIS ON BEHAVIORAL 2831 01:39:51,360 --> 01:39:53,080 CONDITIONING OF MAKING SURE THAT 2832 01:39:53,080 --> 01:39:55,800 HABITS THAT BECOME HABITS ARE 2833 01:39:55,800 --> 01:39:57,160 NICKED EARLY IN THE BUD ARE 2834 01:39:57,160 --> 01:39:58,000 VERY, VERY IMPORTANT FOR THIS 2835 01:39:58,000 --> 01:40:03,640 KIND OF CANCER, SO AS FOR ORAL 2836 01:40:03,640 --> 01:40:04,080 CANCERS IN GENERAL. 2837 01:40:04,080 --> 01:40:08,440 I WAS VERY PLEASED SO SEE FROM 2838 01:40:08,440 --> 01:40:11,080 OUR VERY INNOVATIVE PARTNERSHIP 2839 01:40:11,080 --> 01:40:12,360 INITIATIVE THAT FRANCIS COLLINS 2840 01:40:12,360 --> 01:40:14,480 WAS RESPONSIBLE FOR SETTING UP 2841 01:40:14,480 --> 01:40:16,520 SEVEN YEARS AGO, BRINGING TO THE 2842 01:40:16,520 --> 01:40:19,360 TABLE INDUSTRY PARTNERS, 2843 01:40:19,360 --> 01:40:21,240 GOVERNMENT, ACADEMIA AND NIH, TO 2844 01:40:21,240 --> 01:40:22,640 REALLY SOLVING THE MOST 2845 01:40:22,640 --> 01:40:24,400 DIFFICULT ISSUES, THE MOST 2846 01:40:24,400 --> 01:40:28,240 COMPOUND DISEASES LOOKED AT 2847 01:40:28,240 --> 01:40:30,840 SERIOUSLY: DIABETES, 2848 01:40:30,840 --> 01:40:31,600 PARKINSON'S, ALZHEIMER'S. 2849 01:40:31,600 --> 01:40:34,920 SO THEY'VE MADE GOOD PROGRESS IN 2850 01:40:34,920 --> 01:40:36,240 AUTOIMMUNE DISORDERS, ON 2851 01:40:36,240 --> 01:40:38,520 SYSTEMIC LUPUS AND RHEUMATOID 2852 01:40:38,520 --> 01:40:40,000 ARTHRITIS, TO WHERE FRANCIS FELT 2853 01:40:40,000 --> 01:40:44,480 THAT SHOW GRINS SJOGREN'SF 2854 01:40:44,480 --> 01:40:45,760 THIS, AND WE JUMPED AT THE 2855 01:40:45,760 --> 01:40:46,200 OPPORTUNITY. 2856 01:40:46,200 --> 01:40:48,720 WE NOW HAVE A GRANT THAT 2857 01:40:48,720 --> 01:40:50,120 INVOLVES ACADEMIC PARTNERS AT 2858 01:40:50,120 --> 01:40:52,440 OKLAHOMA AND JOHNS HOPKINS WITH 2859 01:40:52,440 --> 01:40:53,640 OTHER INSTITUTES HERE INVOLVED, 2860 01:40:53,640 --> 01:40:54,800 ALONG WITH OUR INTRAMURAL 2861 01:40:54,800 --> 01:40:57,040 PROGRAM THAT HAS A VERY RICH 2862 01:40:57,040 --> 01:40:59,200 HISTORY IN SALIVARY GLAND 2863 01:40:59,200 --> 01:41:01,640 BIOLOGY AND RECONSTRUCTION. 2864 01:41:01,640 --> 01:41:05,640 TO LOOK AT THIS DISEASE FROM 2865 01:41:05,640 --> 01:41:10,160 START OH TO FINISH, WELL 2866 01:41:10,160 --> 01:41:10,920 CHARACTERIZED, WE'VE ALREADY GOT 2867 01:41:10,920 --> 01:41:13,040 A LARGE COLLECTION OF 2868 01:41:13,040 --> 01:41:14,080 BIOSPECIMENS AND TAKE IT UP FROM 2869 01:41:14,080 --> 01:41:18,640 THE DEACON STRUCKTIVE MODE F 2870 01:41:18,640 --> 01:41:20,920 SINGLE CELL ANALYSIS, PUTTING T 2871 01:41:20,920 --> 01:41:24,120 BACK TOGETHER AND COMING UP WITH 2872 01:41:24,120 --> 01:41:26,840 THERAPEUTIC PRODUCTS THAT WOULD 2873 01:41:26,840 --> 01:41:28,760 HALT THE PROGRESS OF THIS QUITE 2874 01:41:28,760 --> 01:41:29,200 DEVASTATING DISEASE. 2875 01:41:29,200 --> 01:41:31,080 HELENE AND I WOULD BOTH AGREE 2876 01:41:31,080 --> 01:41:32,760 THAT THE TRANS-NIH ACTIVITIES 2877 01:41:32,760 --> 01:41:34,600 ARE TRULY EXCITING, AND WE HAVE 2878 01:41:34,600 --> 01:41:37,360 TO BE AT THE TABLE TO INTEGRATE 2879 01:41:37,360 --> 01:41:42,160 AS BEST AS WE CAN. 2880 01:41:42,160 --> 01:41:43,680 I THINK WE SHARE SOME OF THE 2881 01:41:43,680 --> 01:41:45,120 STRUGGLES AND SOME OF THE GREAT 2882 01:41:45,120 --> 01:41:47,240 SUCCESS STORIES HERE IN THIS 2883 01:41:47,240 --> 01:41:49,640 EFFORT, AND YOU CAN SEE THAT 2884 01:41:49,640 --> 01:41:52,040 RANGE FROM THE CANCER MOONSHOT 2885 01:41:52,040 --> 01:41:53,800 TO BRAIN IMAGING TECHNOLOGIES, 2886 01:41:53,800 --> 01:41:56,280 THAT THERE IS AN APPLICATION FOR 2887 01:41:56,280 --> 01:41:57,640 US IN ORAL HEALTH AS IT MUST BE 2888 01:41:57,640 --> 01:41:57,840 HERE. 2889 01:41:57,840 --> 01:42:01,880 SO I JUST ACTUALLY HAVE DONE AN 2890 01:42:01,880 --> 01:42:04,280 IN DEPTH INTERVIEW WITH REBECCA 2891 01:42:04,280 --> 01:42:07,800 BAKER WHO ACTUALLY RUNS IT SO 2892 01:42:07,800 --> 01:42:08,880 EFFICIENTLY. 2893 01:42:08,880 --> 01:42:10,600 IT'S DIVIDED INTO PAIN 2894 01:42:10,600 --> 01:42:11,840 MANAGEMENT AND SUBSTANCE USE 2895 01:42:11,840 --> 01:42:13,360 DISORDERS. 2896 01:42:13,360 --> 01:42:16,880 DENTISTS AND ORAL HEALTH -- ARE 2897 01:42:16,880 --> 01:42:20,080 VERY INVOLVED INITIALLY FOR 2898 01:42:20,080 --> 01:42:20,440 OVERPRESCRIBING. 2899 01:42:20,440 --> 01:42:22,840 THAT TREND HAS ACTUALLY DECLINED 2900 01:42:22,840 --> 01:42:23,480 OVER THE YEARS. 2901 01:42:23,480 --> 01:42:25,200 SO WE HAVE TWO MAJOR 2902 01:42:25,200 --> 01:42:27,320 INITIATIVES. 2903 01:42:27,320 --> 01:42:29,920 THE FIRST ONE WAS INITIATED BY 2904 01:42:29,920 --> 01:42:31,920 NCCIH ON MYOFASCIAL TISSUES AND 2905 01:42:31,920 --> 01:42:34,760 CLINICAL PAIN MANAGEMENT. 2906 01:42:34,760 --> 01:42:36,080 AND VERY RECENTLY DRIVEN REALLY 2907 01:42:36,080 --> 01:42:39,480 BY THE LEADERSHIP OF HELENE, WE 2908 01:42:39,480 --> 01:42:40,600 HAVE THIS MULTI-INSTITUTE 2909 01:42:40,600 --> 01:42:42,680 PARTNERSHIP ON RE-JOIN, WHICH IS 2910 01:42:42,680 --> 01:42:44,760 FOCUSED ON UNDERSTANDING THE 2911 01:42:44,760 --> 01:42:48,680 NEURAL PATHWAYS IN JOIN, SUCH AS 2912 01:42:48,680 --> 01:42:52,200 THE KNEE JOINT AND 2913 01:42:52,200 --> 01:42:54,160 TEMPOROMANDIBULAR JOINT. 2914 01:42:54,160 --> 01:42:55,600 THEY HAVE DIFFERENT CHALLENGES 2915 01:42:55,600 --> 01:42:56,840 AND I'LL SHOW YOU WHY. 2916 01:42:56,840 --> 01:43:01,520 BECAUSE HERE YOU HAVE THE JOINT. 2917 01:43:01,520 --> 01:43:03,600 LET ME SEE IF I CAN POSSIBLY -- 2918 01:43:03,600 --> 01:43:05,720 THE HEAD OF THE CONDYLE 2919 01:43:05,720 --> 01:43:08,440 ARTICULATES IN THIS LITTLE FOSSA 2920 01:43:08,440 --> 01:43:11,880 AND THERE'S THIS FIBER CARTILAGE 2921 01:43:11,880 --> 01:43:13,200 HERE, NOT THE SAME AS YOU SEE IN 2922 01:43:13,200 --> 01:43:14,880 THE KNEE JOINT. 2923 01:43:14,880 --> 01:43:16,760 FIBER CARTILAGE DEGENERATES FAST 2924 01:43:16,760 --> 01:43:17,840 AND CANNOT GENERATE EASILY. 2925 01:43:17,840 --> 01:43:19,600 IT'S AVASCULAR, IT'S NOT 2926 01:43:19,600 --> 01:43:20,240 INNERVATED EITHER. 2927 01:43:20,240 --> 01:43:23,520 SO IT'S VERY PRONE TO 2928 01:43:23,520 --> 01:43:25,720 DESTRUCTION AND CAN'T REPAIR 2929 01:43:25,720 --> 01:43:26,480 ITSELF EASILY. 2930 01:43:26,480 --> 01:43:29,480 SO WE START OFF THERE, 2931 01:43:29,480 --> 01:43:31,200 PERIARTICULAR TISSUES AROUND THE 2932 01:43:31,200 --> 01:43:33,640 JOINT ARE REALLY WHAT SETS THE 2933 01:43:33,640 --> 01:43:39,200 JOINT UP FOR A DISEASE PROCESS. 2934 01:43:39,200 --> 01:43:42,160 BECAUSE IT'S A VERY FINALLY 2935 01:43:42,160 --> 01:43:43,400 CONNECTED NEUROMUSCULAR TISSUE 2936 01:43:43,400 --> 01:43:46,640 WHERE FASCIA PLAYS A HUGE ROLE, 2937 01:43:46,640 --> 01:43:48,400 SO IF YOU LOOK AT THE 2938 01:43:48,400 --> 01:43:49,040 DYSFUNCTION ITSELF, THEY NO 2939 01:43:49,040 --> 01:43:52,640 LONGER CALL IT TEMPOROMANDIBULAR 2940 01:43:52,640 --> 01:43:52,840 JOINT. 2941 01:43:52,840 --> 01:43:53,640 IT'S TEMPOROMANDIBULAR 2942 01:43:53,640 --> 01:43:54,320 DYSFUNCTION BECAUSE IT'S NOT 2943 01:43:54,320 --> 01:43:55,640 JUST THE JOINT ITSELF. 2944 01:43:55,640 --> 01:43:58,240 IT INVOLVES THE JOINT 2945 01:43:58,240 --> 01:44:00,320 PRINCIPALLY BUT ALSO THE MUSCLES 2946 01:44:00,320 --> 01:44:01,480 AND THE FASCIA AND EVERYTHING 2947 01:44:01,480 --> 01:44:03,280 THAT GOES WITH IT. 2948 01:44:03,280 --> 01:44:04,400 THE ATTACHMENTS, THE TENDONS, 2949 01:44:04,400 --> 01:44:05,720 THE LIGAMENTS. 2950 01:44:05,720 --> 01:44:07,800 AND VERY OFTEN THE SYMPTOMS ARE 2951 01:44:07,800 --> 01:44:11,080 ALSO VERY, VERY COMPLEX AND 2952 01:44:11,080 --> 01:44:12,320 INDICATIVE AT THE START OF THE 2953 01:44:12,320 --> 01:44:12,600 DISEASE. 2954 01:44:12,600 --> 01:44:14,800 SO THIS IS MY ASK FOR YOU, IS 2955 01:44:14,800 --> 01:44:16,360 THAT WE REALLY WANT YOU AT THE 2956 01:44:16,360 --> 01:44:17,640 TABLE AS A PARTNER, BECAUSE WE 2957 01:44:17,640 --> 01:44:19,920 CANNOT DO THIS IN A 2958 01:44:19,920 --> 01:44:20,400 UNIDIRECTIONAL MANNER. 2959 01:44:20,400 --> 01:44:22,960 IT HAS TO BE A PARTNERSHIP WITH 2960 01:44:22,960 --> 01:44:26,640 NCCIH AND SOME OTHER INSTITUTES. 2961 01:44:26,640 --> 01:44:27,960 SO FAR, I LOOKED UP EVERYTHING 2962 01:44:27,960 --> 01:44:30,880 THAT WE WERE INVOLVED WITH, WITH 2963 01:44:30,880 --> 01:44:31,920 NCCIH, AND THESE ARE THE 2964 01:44:31,920 --> 01:44:34,400 INITIATIVES THAT WE HAVE A 2965 01:44:34,400 --> 01:44:35,840 COMMON INTEREST IN AND WE HAVE 2966 01:44:35,840 --> 01:44:36,280 PARTNERSHIP ON. 2967 01:44:36,280 --> 01:44:39,760 YOU CAN SEE IT VARIES FROM 2968 01:44:39,760 --> 01:44:42,160 LOOKING AT OMEGA 6 DIETS, PAPER 2969 01:44:42,160 --> 01:44:47,280 MANAGEMENT AND SO PN 2970 01:44:47,280 --> 01:44:50,200 MANAGEMENT AND CONTROL OF PAIN, 2971 01:44:50,200 --> 01:44:50,560 MUSIC. 2972 01:44:50,560 --> 01:44:51,600 IT'S A PORTFOLIO THAT LENDS 2973 01:44:51,600 --> 01:44:52,960 ITSELF TO EXPANSION IN EVERY 2974 01:44:52,960 --> 01:44:53,400 AREA. 2975 01:44:53,400 --> 01:44:54,720 NOW WHERE I SEE OURSELVES 2976 01:44:54,720 --> 01:44:56,000 MOVING, IF I CAN PROJECT A BIT 2977 01:44:56,000 --> 01:44:57,560 FOR THE FUTURE, IT WOULD BE IN 2978 01:44:57,560 --> 01:45:01,840 THE AREA OF PAIN FOR SURE. 2979 01:45:01,840 --> 01:45:03,360 WE STRUGGLE AND WITH VERY 2980 01:45:03,360 --> 01:45:06,520 DISTINCT OROFACIAL PAIN 2981 01:45:06,520 --> 01:45:08,760 PHENOMENA THAT ARE HARD TO 2982 01:45:08,760 --> 01:45:11,200 CALIBRATE SOMETIMES AND EVEN 2983 01:45:11,200 --> 01:45:11,880 STRATIFY. 2984 01:45:11,880 --> 01:45:15,720 WE NEED DO THAT, WITH A BETTER 2985 01:45:15,720 --> 01:45:16,320 THESAURUS. 2986 01:45:16,320 --> 01:45:17,800 WE NEED HEALTH APPROACHES AND 2987 01:45:17,800 --> 01:45:19,640 INTEGRATIVE TREATMENTS FOR EVERY 2988 01:45:19,640 --> 01:45:21,960 ONE OF OUR DISEASES AND 2989 01:45:21,960 --> 01:45:22,280 DISORDERS. 2990 01:45:22,280 --> 01:45:26,040 WE HAVE TO, I THINK, INSTITUTE 2991 01:45:26,040 --> 01:45:27,360 MUCH MORE OF A PREVENTIVE AIF 2992 01:45:27,360 --> 01:45:29,320 PROACH TO EVERYTHING WE DO, AND 2993 01:45:29,320 --> 01:45:31,120 TO PROBE INTERCEPTOR PROCESS IN 2994 01:45:31,120 --> 01:45:32,600 THE CONTEXT OF ORAL DISEASE, 2995 01:45:32,600 --> 01:45:34,360 BECAUSE IT IS, IN FACT, 2996 01:45:34,360 --> 01:45:34,920 AFFECTING GENERAL HEALTH AND 2997 01:45:34,920 --> 01:45:35,560 WELL-BEING. 2998 01:45:35,560 --> 01:45:38,640 SO THIS IS WHERE I WOULD END, 2999 01:45:38,640 --> 01:45:40,800 WHICH IS I'VE SPECIFIED THE 3000 01:45:40,800 --> 01:45:42,440 PROBLEMS, I'VE ENVISIONED A PLAN 3001 01:45:42,440 --> 01:45:44,640 THAT I'M HOPING THE INSTITUTE 3002 01:45:44,640 --> 01:45:47,920 WILL MOVE ALONG IN A VERY, VERY 3003 01:45:47,920 --> 01:45:49,240 INTENTIONAL WAY, AND I'M HOPING 3004 01:45:49,240 --> 01:45:50,400 THAT THE RESULTS WILL ACTUALLY 3005 01:45:50,400 --> 01:45:53,160 BE ORAL HEALTH FOR ALL. 3006 01:45:53,160 --> 01:45:54,360 THROUGH INTEGRATION, THROUGH 3007 01:45:54,360 --> 01:45:57,800 INNOVATION AND BY INSPIRING 3008 01:45:57,800 --> 01:45:58,600 THOSE THAT WE MENTOR. 3009 01:45:58,600 --> 01:46:00,560 I WANT TO THANK MY STAFF WHO ARE 3010 01:46:00,560 --> 01:46:03,000 EXTREMELY SUPPORTIVE AND 3011 01:46:03,000 --> 01:46:03,840 TALENTED, DEDICATED GROUP. 3012 01:46:03,840 --> 01:46:06,240 IT'S REALLY A PRIVILEGE AND AN 3013 01:46:06,240 --> 01:46:09,080 HONOR TO BE HERE EVEN IF IT'S 3014 01:46:09,080 --> 01:46:09,320 VIRTUAL. 3015 01:46:09,320 --> 01:46:09,640 THANK YOU. 3016 01:46:09,640 --> 01:46:13,280 ANY QUESTIONS AND COMMENTS? 3017 01:46:13,280 --> 01:46:18,080 I'M HAPPY TO TAKE THAT. 3018 01:46:18,080 --> 01:46:19,600 >> THANK YOU SO MUCH. 3019 01:46:19,600 --> 01:46:23,080 RENA, THIS WAS SO OUTSTANDING. 3020 01:46:23,080 --> 01:46:24,440 IT'S SO IMPRESSIVE TO SEE IN THE 3021 01:46:24,440 --> 01:46:25,960 SHORT AMOUNT OF TIME THAT YOU'VE 3022 01:46:25,960 --> 01:46:28,360 BEEN AT NIH AND THE LEADERSHIP 3023 01:46:28,360 --> 01:46:30,000 THAT YOU'RE SHOWING AND THIS 3024 01:46:30,000 --> 01:46:31,120 WONDERFUL SPIRIT OF 3025 01:46:31,120 --> 01:46:31,920 COLLABORATION. 3026 01:46:31,920 --> 01:46:33,760 I REALLY -- I'M JUST SO 3027 01:46:33,760 --> 01:46:37,120 IMPRESSED AND IT'S WONDERFUL TO 3028 01:46:37,120 --> 01:46:38,440 HAVE YOU AS A COLLEAGUE. 3029 01:46:38,440 --> 01:46:44,760 WE HAVE A FEW MINUTES FOR 3030 01:46:44,760 --> 01:46:47,000 QUESTIONS. 3031 01:46:47,000 --> 01:46:48,480 I HAVE A QUESTION BUT I'LL LET 3032 01:46:48,480 --> 01:46:49,600 OTHERS JUMP IN FIRST. 3033 01:46:49,600 --> 01:46:53,000 RICK AND THEN NADJA. 3034 01:46:53,000 --> 01:46:54,200 >> THANK YOU VERY MUCH FOR THAT 3035 01:46:54,200 --> 01:46:54,720 WONDERFUL TALK. 3036 01:46:54,720 --> 01:46:56,360 I REALLY, REALLY ENJOYED 3037 01:46:56,360 --> 01:47:00,120 LISTENING TO IT. 3038 01:47:00,120 --> 01:47:01,920 I WAS WONDERING IF THERE MIGHT 3039 01:47:01,920 --> 01:47:04,960 BE SOME OVERLAPS BETWEEN YOUR 3040 01:47:04,960 --> 01:47:06,080 INSTITUTE AND NCCIH, 3041 01:47:06,080 --> 01:47:08,920 PARTICULARLILY WITH THE TURNG. 3042 01:47:08,920 --> 01:47:09,440 TONGUE. 3043 01:47:09,440 --> 01:47:12,200 IN TRADITIONAL CHINESE MEDICINE, 3044 01:47:12,200 --> 01:47:13,720 THERE'S DIFFERENT THEORIES ABOUT 3045 01:47:13,720 --> 01:47:15,040 WHAT THE TONGUE LOOKS LIKE, 3046 01:47:15,040 --> 01:47:15,760 COLOR, EVERYTHING ABOUT THE 3047 01:47:15,760 --> 01:47:17,440 TONGUE CAN BE IMPORTANT IN 3048 01:47:17,440 --> 01:47:19,240 DIAGNOSES, AND I WAS WONDERING 3049 01:47:19,240 --> 01:47:21,520 IF THERE'S ANY OVERLAB THERE. 3050 01:47:21,520 --> 01:47:25,560 >> HUGE AMOUNT, RICK. 3051 01:47:25,560 --> 01:47:28,160 HUGE. 3052 01:47:28,160 --> 01:47:29,360 EVEN WITH COVID AND THE TASTE 3053 01:47:29,360 --> 01:47:31,800 BEING SO AFFECTED AND SO EARLY 3054 01:47:31,800 --> 01:47:33,560 ON, WE HAVE A POCKET OF 3055 01:47:33,560 --> 01:47:34,400 RESEARCHERS LOOKING AT THE 3056 01:47:34,400 --> 01:47:39,920 PHYSIOLOGY OF TASTE AND 3057 01:47:39,920 --> 01:47:41,400 SENSATIONS, LOOKING AT THE TURNG 3058 01:47:41,400 --> 01:47:44,280 IN ITS NEUROMUSCULAR CAPACITY, 3059 01:47:44,280 --> 01:47:53,080 AS AN INDICATOR OF VITAMIN 3060 01:47:53,080 --> 01:47:55,040 DEFICIENCY, IS IT OFTENTIMES 3061 01:47:55,040 --> 01:47:56,280 EVALUATED IN THE CLINICAL EXAM? 3062 01:47:56,280 --> 01:47:58,880 >> IN TRADITIONAL CLIE NIECE MED 3063 01:47:58,880 --> 01:48:01,480 SIGN, MANY TIMES THE TONGUE IS 3064 01:48:01,480 --> 01:48:03,000 LOOKED AT AS AN INDICATOR OF 3065 01:48:03,000 --> 01:48:04,200 WHAT THE INTERNAL ORGANS MIGHT 3066 01:48:04,200 --> 01:48:08,360 BE DOING AND HOW THE HOMEOSTASIS 3067 01:48:08,360 --> 01:48:10,000 OF THE INTERNAL BODY SYSTEM IS, 3068 01:48:10,000 --> 01:48:12,120 SO IT'S KIND OF A WINDOW TO THE 3069 01:48:12,120 --> 01:48:13,400 INSIDE THAT'S MANY TIMES USED IN 3070 01:48:13,400 --> 01:48:17,480 INITIAL DIAGNOSIS. 3071 01:48:17,480 --> 01:48:19,560 THE COLOR, SHAPE, COATING, LOTS 3072 01:48:19,560 --> 01:48:21,440 OF THINGS YOU CAN JUST TELL BY 3073 01:48:21,440 --> 01:48:21,640 LOOKING. 3074 01:48:21,640 --> 01:48:22,280 >> YES. 3075 01:48:22,280 --> 01:48:28,200 AND WE HAVE A HOST OF DISEASES 3076 01:48:28,200 --> 01:48:29,720 ALL OF WHICH AFFECT THE TONGUE, 3077 01:48:29,720 --> 01:48:32,120 THOSE ARE ACTUAL PATHOLOGIES BUT 3078 01:48:32,120 --> 01:48:33,880 YOU CAN ALSO GET A FIRM 3079 01:48:33,880 --> 01:48:35,320 INDICATION OF OVERALL HEALTH BY 3080 01:48:35,320 --> 01:48:45,680 LOOKING AT THE TONGUE. 3081 01:48:46,320 --> 01:48:46,440 NADJA? 3082 01:48:46,440 --> 01:48:47,560 >> THANK YOU SO MUCH. 3083 01:48:47,560 --> 01:48:52,920 YOU JUST REALLY JUST REAR 3084 01:48:52,920 --> 01:48:54,120 PRESENTATION AND I'M REALLY 3085 01:48:54,120 --> 01:48:55,120 INSPIRED BY THE WORK THAT YOU'VE 3086 01:48:55,120 --> 01:48:56,240 DONE TRANSITIONING FROM BEING ON 3087 01:48:56,240 --> 01:48:57,880 THE GROUND AND SEEING PATIENTS 3088 01:48:57,880 --> 01:48:59,680 AND THEN MOVING TOWARDS BEING 3089 01:48:59,680 --> 01:49:03,200 MORE INVOLVED IN POLICY AND 3090 01:49:03,200 --> 01:49:05,400 HAVING THAT REALLY INFORMED BY 3091 01:49:05,400 --> 01:49:06,200 YOUR ON THE GROUND EXPERIENCE. 3092 01:49:06,200 --> 01:49:08,280 IN THAT REGARD, I JUST WONDERED, 3093 01:49:08,280 --> 01:49:09,480 I KNOW SOME OF THE POPULATIONS 3094 01:49:09,480 --> 01:49:10,800 THAT YOU'VE WORKED WITH IN THE 3095 01:49:10,800 --> 01:49:13,960 PAST WHEN YOU WERE IN PRACTICE, 3096 01:49:13,960 --> 01:49:16,160 ARE SOME OF THE SAME POPULATIONS 3097 01:49:16,160 --> 01:49:18,320 THAT DO USE ALTERNATIVE 3098 01:49:18,320 --> 01:49:19,320 THERAPIES, COMPLEMENTARY 3099 01:49:19,320 --> 01:49:22,280 APPROACHES A GREAT DEAL, WHETHER 3100 01:49:22,280 --> 01:49:23,600 THAT'S APPROACHES FOR PAIN 3101 01:49:23,600 --> 01:49:25,240 MANAGEMENT OR ORAL HYGIENE OR 3102 01:49:25,240 --> 01:49:29,800 THINGS LIKE THIS BASED ON BOW 3103 01:49:29,800 --> 01:49:30,840 TAN YAL KALES OR THINGS LIKE 3104 01:49:30,840 --> 01:49:32,440 THAT AND I WONDERED IF YOU HAD 3105 01:49:32,440 --> 01:49:33,240 ANY PERSONAL EXPERIENCE WITH 3106 01:49:33,240 --> 01:49:35,960 THAT OR ANY PERSONAL INTEREST IN 3107 01:49:35,960 --> 01:49:36,720 THAT CONNECTION BETWEEN IT SEEMS 3108 01:49:36,720 --> 01:49:39,360 LIKE THERE'S A NEED FOR OFTEN 3109 01:49:39,360 --> 01:49:40,240 SURGICAL INTERVENTION BUT THEN 3110 01:49:40,240 --> 01:49:42,000 SOME OF THESE SRP APPROACHES 3111 01:49:42,000 --> 01:49:46,520 MIGHT BE USED FOR PAIN 3112 01:49:46,520 --> 01:49:48,240 MANAGEMENT, RECOVERY, OVERALL 3113 01:49:48,240 --> 01:49:49,200 PAIN MANAGEMENT, THAT HAS 3114 01:49:49,200 --> 01:49:49,880 HAPPENED. 3115 01:49:49,880 --> 01:49:50,960 I JUST WONDERED IF YOU HAD ANY 3116 01:49:50,960 --> 01:49:51,600 PERSONAL THOUGHTS ABOUT THAT. 3117 01:49:51,600 --> 01:49:59,640 >> SUMP A GREAT POINT. 3118 01:49:59,640 --> 01:50:01,800 >> RELATED TO, SAY, THE 3119 01:50:01,800 --> 01:50:03,360 EFFECTIVE ENVIRONMENTAL STRESSES 3120 01:50:03,360 --> 01:50:04,640 ON TOOTH DEVELOPMENT. 3121 01:50:04,640 --> 01:50:07,000 BECAUSE TEETH DEVELOP IN UTERO, 3122 01:50:07,000 --> 01:50:08,720 THEY LAND UP AS BEING VERY 3123 01:50:08,720 --> 01:50:12,680 IMPORTANT BIOLOGIC HARDWARE FOR 3124 01:50:12,680 --> 01:50:13,320 RECORDING THE INSULTS THAT 3125 01:50:13,320 --> 01:50:14,000 ACTUALLY HAPPEN DURING 3126 01:50:14,000 --> 01:50:15,720 PREGNANCY. 3127 01:50:15,720 --> 01:50:16,600 I KNOW PEOPLE DON'T REALIZE 3128 01:50:16,600 --> 01:50:18,560 THAT, BUT YOU GET THESE LITTLE 3129 01:50:18,560 --> 01:50:20,880 ENAMEL DEFECTS THEY CALL 3130 01:50:20,880 --> 01:50:22,160 HYPERMINERALIZATION DEFECTS ON 3131 01:50:22,160 --> 01:50:23,600 BABY TEETH AS WELL AS PERMANENT 3132 01:50:23,600 --> 01:50:26,000 FIRST MOLARS THAT REFLECT THAT 3133 01:50:26,000 --> 01:50:30,360 THE MOTHER WAS EXPOSED TO SOME 3134 01:50:30,360 --> 01:50:35,440 VIECIALT TALL VERY 3135 01:50:35,440 --> 01:50:36,720 ENVIRONMENTAL STRESSOR, IT'S 3136 01:50:36,720 --> 01:50:38,600 RECORDED IN YOUR TEETH. 3137 01:50:38,600 --> 01:50:39,920 ALTERNATIVE APPROACHES, 3138 01:50:39,920 --> 01:50:40,600 DENTISTRY AND ORAL HEALTH 3139 01:50:40,600 --> 01:50:42,040 PRACTICE IN THE U.S. IS VERY, 3140 01:50:42,040 --> 01:50:43,000 VERY TRADITIONAL. 3141 01:50:43,000 --> 01:50:47,040 VERY CONSERVATIVE, VERY 3142 01:50:47,040 --> 01:50:49,000 PROCEDURE-DEPENDENT, 3143 01:50:49,000 --> 01:50:49,600 INTERVENTION-DEPENDENT RATHER 3144 01:50:49,600 --> 01:50:50,240 THAN PREVENTION, AND THAT MOST 3145 01:50:50,240 --> 01:50:52,640 OF THE PRACTICES THAT INVOLVE 3146 01:50:52,640 --> 01:50:53,840 HOMEOPATHY, AYURVEDICS ARE 3147 01:50:53,840 --> 01:50:55,040 OCCURRING OUTSIDE THE COUNTRY IN 3148 01:50:55,040 --> 01:50:58,240 DIFFERENT PARTS OF WORLD. 3149 01:50:58,240 --> 01:50:59,680 IN CHINESE MEDICINE IN INDIA, 3150 01:50:59,680 --> 01:51:02,400 FOR SURE ALL OF THAT IS 3151 01:51:02,400 --> 01:51:04,680 HAPPENING, AND EXCEPT FOR THE 3152 01:51:04,680 --> 01:51:05,480 TEMPOROMANDIBULAR JOINT WHERE 3153 01:51:05,480 --> 01:51:08,000 IT'S GONE INTO THE GREY AREA 3154 01:51:08,000 --> 01:51:10,840 OF -- I WOULDN'T CALL IT VOODOO 3155 01:51:10,840 --> 01:51:13,480 DENTISTRY BUT IT'S IN THE 3156 01:51:13,480 --> 01:51:14,280 PSYCHOSOMATIC RANGE ONLY BECAUSE 3157 01:51:14,280 --> 01:51:15,760 YOU WALK INTO AN OFFICE WITH 3158 01:51:15,760 --> 01:51:17,200 FLASHY LIGHTS AND THINGS THAT 3159 01:51:17,200 --> 01:51:18,840 YOU JUST CAN'T PUT YOUR FINGER 3160 01:51:18,840 --> 01:51:20,280 ON BECAUSE PEOPLE DON'T 3161 01:51:20,280 --> 01:51:21,040 UNDERSTAND THE DISEASE. 3162 01:51:21,040 --> 01:51:23,320 SO I THINK IN THAT AREA, THERE 3163 01:51:23,320 --> 01:51:24,520 ARE ALTERNATIVE APPROACHES BUT 3164 01:51:24,520 --> 01:51:26,880 NOT THE KIND THAT YOU'RE 3165 01:51:26,880 --> 01:51:27,160 THINKING. 3166 01:51:27,160 --> 01:51:28,800 BUT NOT IN GENERAL, NO, I 3167 01:51:28,800 --> 01:51:30,880 WOULDN'T SAY UNLESS I'M NOT 3168 01:51:30,880 --> 01:51:32,080 KEEPING ON TOP OF WHAT'S 3169 01:51:32,080 --> 01:51:32,760 HAPPENING IN THE FIELD. 3170 01:51:32,760 --> 01:51:35,920 I WILL TAKE A LOOK AT THAT AND 3171 01:51:35,920 --> 01:51:41,200 SEE IF THERE ARE ANY -- YOU CAN 3172 01:51:41,200 --> 01:51:42,400 PUT ON A TOOTH THAT'S THROBING 3173 01:51:42,400 --> 01:51:44,920 WITH PAIN. 3174 01:51:44,920 --> 01:51:46,480 TYPICALLY IT'S ZINC OXIDE 3175 01:51:46,480 --> 01:51:48,280 EUGENOL, WHICH IS CLOVE OIL. 3176 01:51:48,280 --> 01:51:48,960 WE STILL USE THAT. 3177 01:51:48,960 --> 01:51:51,840 AND THAT IN A SENSE IS A 3178 01:51:51,840 --> 01:51:54,240 BIOLOGICAL DERIVATIVE. 3179 01:51:54,240 --> 01:51:59,160 IT'S A GOOD THING, BECAUSE WE 3180 01:51:59,160 --> 01:52:00,560 CERTAINLY NEED THE BEHAVIORAL 3181 01:52:00,560 --> 01:52:02,560 CONDITIONING ASPECTS OF MUCH 3182 01:52:02,560 --> 01:52:04,520 MORE REINFORCED IN OUR PRACTICE 3183 01:52:04,520 --> 01:52:07,160 AND OUR PRINCIPLES OF PRACTICE. 3184 01:52:07,160 --> 01:52:09,120 SO THANK YOU FOR THAT. 3185 01:52:09,120 --> 01:52:11,840 >> THANK YOU. 3186 01:52:11,840 --> 01:52:13,240 >> SO I HAVE ONE QUESTION IF 3187 01:52:13,240 --> 01:52:14,880 THERE'S NO OTHER QUESTIONS OR 3188 01:52:14,880 --> 01:52:15,800 COMMENTS, BECAUSE I WANTED TO 3189 01:52:15,800 --> 01:52:18,960 FOLLOW UP ON RICK'S QUESTION 3190 01:52:18,960 --> 01:52:20,080 ABOUT TRADITIONAL CHINESE 3191 01:52:20,080 --> 01:52:20,360 MEDICINE. 3192 01:52:20,360 --> 01:52:22,240 ONE OF THE REASONS IS THAT IN 3193 01:52:22,240 --> 01:52:23,960 OUR STRATEGIC PLAN, ONE OF THE 3194 01:52:23,960 --> 01:52:27,160 THINGS THAT WE'VE PUT IN ONE OF 3195 01:52:27,160 --> 01:52:33,080 OUR FIRST STRATEGIC AIM IS TO 3196 01:52:33,080 --> 01:52:35,160 LOOK AT WHAT WE CALL DIAGNOSTIC 3197 01:52:35,160 --> 01:52:36,840 SYSTEMS AND THERAPEUTIC SYSTEMS, 3198 01:52:36,840 --> 01:52:38,680 BUT PRIMARILY DIAGNOSTIC, THAT 3199 01:52:38,680 --> 01:52:40,320 ARE DIFFERENT FROM THOSE OF 3200 01:52:40,320 --> 01:52:43,480 CONVENTIONAL MEDICINE. 3201 01:52:43,480 --> 01:52:44,640 SO AIR VAI DA, YOU MENTIONED 3202 01:52:44,640 --> 01:52:46,800 COULD BE ONE OF THEM, 3203 01:52:46,800 --> 01:52:47,400 TRADITIONAL CHINESE MEDICINE 3204 01:52:47,400 --> 01:52:49,080 WHERE THE PRACTITIONER 3205 01:52:49,080 --> 01:52:51,480 INTERPRETS THE PERSON'S SIGNS AN 3206 01:52:51,480 --> 01:52:54,080 SYMPTOMS IN A WAY THAT IS A 3207 01:52:54,080 --> 01:53:00,040 DIFFERENT FRAMEWORK, SIGNS AND 3208 01:53:00,040 --> 01:53:00,680 SYMPTOMS ARE LOOKED AT 3209 01:53:00,680 --> 01:53:01,440 DIFFERENTLY IN ORDER TO COME TO 3210 01:53:01,440 --> 01:53:01,960 A DIAGNOSIS. 3211 01:53:01,960 --> 01:53:03,320 A LOT OF THESE DIAGNOSES ARE 3212 01:53:03,320 --> 01:53:04,720 VERY, VERY -- THEY DON'T OVERLAP 3213 01:53:04,720 --> 01:53:08,000 REALLY WITH OUR DIAGNOSES. 3214 01:53:08,000 --> 01:53:08,960 SO ONE OF THE THINGS WE WANT TO 3215 01:53:08,960 --> 01:53:12,920 DO IS TO HAVE SOME INITIATIVES 3216 01:53:12,920 --> 01:53:15,400 TO VALIDATE ESSENTIALLY THESE 3217 01:53:15,400 --> 01:53:19,360 DIAGNOSES AND DO INTERRATER 3218 01:53:19,360 --> 01:53:20,080 RELIABILITY, FOR EXAMPLE. 3219 01:53:20,080 --> 01:53:21,800 ONE OF THE THINGS THAT RICK WAS 3220 01:53:21,800 --> 01:53:23,040 MENTIONING, SAY TAKE 10 3221 01:53:23,040 --> 01:53:24,400 DIFFERENT PRACTITIONERS OF 3222 01:53:24,400 --> 01:53:25,600 TRADITIONAL CHINESE MEDICINE AND 3223 01:53:25,600 --> 01:53:29,000 SHOW THEM 10 DIFFERENT TONGUES 3224 01:53:29,000 --> 01:53:30,600 AND SEE WHETHER THEY, FIRST OF 3225 01:53:30,600 --> 01:53:31,480 ALL, AGREEL ON WHAT THE SIGNS 3226 01:53:31,480 --> 01:53:33,920 AND SYMPTOMS ARE, AND HOW DO 3227 01:53:33,920 --> 01:53:35,120 THEY INTERPRET IT, WHAT DO THEY 3228 01:53:35,120 --> 01:53:36,520 DIAGNOSE BASED ON THAT. 3229 01:53:36,520 --> 01:53:38,400 THIS MIGHT BE A REALLY 3230 01:53:38,400 --> 01:53:40,400 INTERESTING -- AND THEN USE THE 3231 01:53:40,400 --> 01:53:41,560 PRACTITIONERS WHO ARE TRAINED, 3232 01:53:41,560 --> 01:53:45,320 YOU KNOW, IN THIS PARTICULAR 3233 01:53:45,320 --> 01:53:46,240 METHOD, DIAGNOSTIC METHOD TO 3234 01:53:46,240 --> 01:53:47,480 INFORM THE RESEARCH QUESTION. 3235 01:53:47,480 --> 01:53:48,920 SO I THOUGHT THIS MIGHT BE AN 3236 01:53:48,920 --> 01:53:51,640 AREA WHERE WE COULD COLLABORATE. 3237 01:53:51,640 --> 01:53:52,640 IT WOULD BE VERY INTERESTING, 3238 01:53:52,640 --> 01:53:53,000 WOULDN'T IT? 3239 01:53:53,000 --> 01:53:53,960 >> YES. 3240 01:53:53,960 --> 01:53:55,680 ESPECIALLY NOW IN THE AGE OF 3241 01:53:55,680 --> 01:53:59,280 DIGITAL IMAGING WHERE INTRAORAL 3242 01:53:59,280 --> 01:54:01,360 PHOTOGRAPHY IS SO WELL DEFINE 3243 01:54:01,360 --> 01:54:03,040 AND WELL REFINED SO WE CAN HAVE 3244 01:54:03,040 --> 01:54:04,000 AI AND MACHINE LEARNING TOOLS 3245 01:54:04,000 --> 01:54:05,480 THAT WOULD ACTUALLY BE 3246 01:54:05,480 --> 01:54:07,120 PREDICTIVE AND DIAGNOSTIC. 3247 01:54:07,120 --> 01:54:08,840 I THINK THAT WOULD BE ONE AREA 3248 01:54:08,840 --> 01:54:11,360 WE COULD INTEGRATE DATA SCIENCE, 3249 01:54:11,360 --> 01:54:11,680 ABSOLUTELY. 3250 01:54:11,680 --> 01:54:12,800 >> I TOTALLY AGREE. 3251 01:54:12,800 --> 01:54:16,160 SO LET'S PUT THAT DOWN. 3252 01:54:16,160 --> 01:54:17,720 >> AND THERE'S LOTS TO TALK 3253 01:54:17,720 --> 01:54:21,320 ABOUT, HELENE, AS YOU KNOW. 3254 01:54:21,320 --> 01:54:24,640 >> GOSH. 3255 01:54:24,640 --> 01:54:25,960 IT HAS BEEN LOVELY TO HAVE YOU, 3256 01:54:25,960 --> 01:54:26,280 RENA. 3257 01:54:26,280 --> 01:54:28,040 WE'RE ACTUALLY OUT OF TIME SO 3258 01:54:28,040 --> 01:54:29,120 WE'RE GOING TO MOVE ON IN OUR 3259 01:54:29,120 --> 01:54:31,200 PROGRAM, BUT WE CANNOT THANK YOU 3260 01:54:31,200 --> 01:54:33,080 ENOUGH FOR TAKING THE TIME TO 3261 01:54:33,080 --> 01:54:34,480 COME AND SPEAK WITH OUR COUNCIL 3262 01:54:34,480 --> 01:54:35,360 AND LOOKING FORWARD TO FOLLOWING 3263 01:54:35,360 --> 01:54:38,080 UP ON ALL THESE IDEAS THAT WE'RE 3264 01:54:38,080 --> 01:54:38,400 DISCUSSING. 3265 01:54:38,400 --> 01:54:38,960 >> THANK YOU. 3266 01:54:38,960 --> 01:54:42,040 AND THANK YOU, DR. KHALSA, FOR 3267 01:54:42,040 --> 01:54:45,880 MAKING ALL OF US WORK ON TIME. 3268 01:54:45,880 --> 01:54:46,960 THANK YOU. 3269 01:54:46,960 --> 01:54:47,200 BYE-BYE. 3270 01:54:47,200 --> 01:54:48,040 >> THANK YOU. 3271 01:54:48,040 --> 01:54:49,720 BYE-BYE. 3272 01:54:49,720 --> 01:54:52,120 >> OKAY. 3273 01:54:52,120 --> 01:54:54,840 WE ARE NOW GOING TO MOVE TO THE 3274 01:54:54,840 --> 01:54:55,960 MINI SYMPOSIUM THAT WE HAVE 3275 01:54:55,960 --> 01:54:56,800 TALKED ABOUT EARLIER, AND I'M 3276 01:54:56,800 --> 01:54:58,040 GOING TO TURN THE MICROPHONE 3277 01:54:58,040 --> 01:55:00,640 OVER TO DR. EDWARDS, WHO WILL 3278 01:55:00,640 --> 01:55:02,480 INTRODUCE DR. WEBER, WHO WILL 3279 01:55:02,480 --> 01:55:05,640 INTRODUCE THE SPEAKERS. 3280 01:55:05,640 --> 01:55:07,000 >> THANKS, PARTAP. 3281 01:55:07,000 --> 01:55:11,360 SO I THINK AS WE CONCEPTUALIZE 3282 01:55:11,360 --> 01:55:13,680 THIS LITTLE MINI SYMPOSIUM, WE 3283 01:55:13,680 --> 01:55:15,080 ACTUALLY DREW BACK FROM OUR 3284 01:55:15,080 --> 01:55:15,920 STRATEGIC PLAN WHERE AT THE END 3285 01:55:15,920 --> 01:55:19,440 OF THE PLAN, YOU CAN FIND OUR 3286 01:55:19,440 --> 01:55:20,560 TOP 10 SCIENTIFIC PRIORITIES. 3287 01:55:20,560 --> 01:55:22,960 ONE OF THEM IS ACTUALLY 3288 01:55:22,960 --> 01:55:24,760 SUPPORTING IMPACTFUL CLINICAL 3289 01:55:24,760 --> 01:55:25,160 TRIALS. 3290 01:55:25,160 --> 01:55:29,960 SO AS WE DISCUSS PUTTING THIS 3291 01:55:29,960 --> 01:55:32,040 SYMPOSIUM TOGETHER, WE ACTUALLY 3292 01:55:32,040 --> 01:55:34,000 COMBINE TWO AREAS OF INTEREST AS 3293 01:55:34,000 --> 01:55:36,280 YOU HEARD EARLIER, WE'RE VERY 3294 01:55:36,280 --> 01:55:37,920 MUCH INTERESTED IN DEVELOPING 3295 01:55:37,920 --> 01:55:44,520 NEW PROGRAM FOR REDUCTION OF 3296 01:55:44,520 --> 01:55:45,920 STRESS, SO WE THOUGHT WE'D PUT 3297 01:55:45,920 --> 01:55:47,480 THE DISCUSSION OF IMPACTFUL 3298 01:55:47,480 --> 01:55:49,640 TRIAL IN THE CONTEXT OF STRESS 3299 01:55:49,640 --> 01:55:51,520 RESEARCH, BUT WE ARE GOING TO 3300 01:55:51,520 --> 01:55:54,160 HAVE WENDY ACTUALLY SET THE 3301 01:55:54,160 --> 01:55:56,640 STAGE, AND WE ALSO INVITED THREE 3302 01:55:56,640 --> 01:55:58,880 OF OUR INVESTIGATORS THAT ARE 3303 01:55:58,880 --> 01:56:01,160 GOING TO ILLUSTRATE THE VARIOUS 3304 01:56:01,160 --> 01:56:04,880 ASPECTS OF WHAT WE CONSIDER AS 3305 01:56:04,880 --> 01:56:06,080 IMPACTFUL TRIAL FROM THE 3306 01:56:06,080 --> 01:56:08,240 PERSPECTIVE OF THE SCIENCE 3307 01:56:08,240 --> 01:56:10,520 THAT'S BEING TARGETED, THE 3308 01:56:10,520 --> 01:56:12,000 APPROACH, THE POPULATIONS THAT 3309 01:56:12,000 --> 01:56:14,840 ARE BEING TARGETED AND ALSO THE 3310 01:56:14,840 --> 01:56:16,720 PROCESS THAT WE FOLLOW. 3311 01:56:16,720 --> 01:56:17,840 SO WITHOUT FURTHER ADO, I'M 3312 01:56:17,840 --> 01:56:19,480 GOING TO TURN IT OVER TO WENDY, 3313 01:56:19,480 --> 01:56:20,920 WHO'S GOING TO SET THE STAGE FOR 3314 01:56:20,920 --> 01:56:22,200 THE REST OF THE PRESENTATION. 3315 01:56:22,200 --> 01:56:23,120 WENDY? 3316 01:56:23,120 --> 01:56:23,520 >> GREAT. 3317 01:56:23,520 --> 01:56:25,520 THANK YOU SO MUCH, EMMELINE. 3318 01:56:25,520 --> 01:56:29,120 LET ME JUST MAKE SURE THAT 3319 01:56:29,120 --> 01:56:30,880 EVERYONE CAN SEE MY SLIDES OKAY. 3320 01:56:30,880 --> 01:56:32,520 AND LET'S SEE IF I CAN GET THEM 3321 01:56:32,520 --> 01:56:38,880 TO GO TO THE CORRECT MODE. 3322 01:56:38,880 --> 01:56:39,760 CAN EVERYBODY SEE THAT? 3323 01:56:39,760 --> 01:56:40,360 GREAT. 3324 01:56:40,360 --> 01:56:42,600 SO IT'S MY PLEASURE TO TALK WITH 3325 01:56:42,600 --> 01:56:47,520 YOU ALL THIS AFTERNOON AND TALK 3326 01:56:47,520 --> 01:56:48,680 TO YOU ABOUT THIS IDEA OF 3327 01:56:48,680 --> 01:56:49,840 CLINICAL TRIALS TO ADDRESS 3328 01:56:49,840 --> 01:56:53,040 STRESS IN DIFFERENT CONTEXTS AND 3329 01:56:53,040 --> 01:56:54,440 WHAT REALLY MAKES TRIALS 3330 01:56:54,440 --> 01:56:54,880 IMPACTFUL. 3331 01:56:54,880 --> 01:56:56,720 SO LET ME START OFF WITH JUST 3332 01:56:56,720 --> 01:56:59,480 DOING A FEW INTRODUCTIONS AND 3333 01:56:59,480 --> 01:57:00,680 OVERVIEW OF WHAT WE'RE GOING TO 3334 01:57:00,680 --> 01:57:01,560 TALK ABOUT THIS AFTERNOON. 3335 01:57:01,560 --> 01:57:02,760 SO I'M GOING TO GIVE A LITTLE 3336 01:57:02,760 --> 01:57:04,600 BIT OF AN INTRODUCTION AND TALK 3337 01:57:04,600 --> 01:57:06,480 A LITTLE BIT ABOUT OUR FRAMEWORK 3338 01:57:06,480 --> 01:57:10,120 FOR CLINICAL TRIAL RESEARCH AND 3339 01:57:10,120 --> 01:57:11,640 WHAT WE THINK SUCCESS WOULD LOOK 3340 01:57:11,640 --> 01:57:13,400 LIKE FOR IMPACTFUL CLINICAL 3341 01:57:13,400 --> 01:57:14,360 TRIALS AND THEN I'M GOING TO 3342 01:57:14,360 --> 01:57:16,680 TURN THINGS OVER TO OUR 3343 01:57:16,680 --> 01:57:17,680 DIFFERENT SPEAKERS. 3344 01:57:17,680 --> 01:57:18,520 DR. MICHAEL CHRISTOPHER IS GOING 3345 01:57:18,520 --> 01:57:20,800 TO TALK ABOUT ADAPTATION AND 3346 01:57:20,800 --> 01:57:22,480 FEASIBILITY OF INTERVENTIONS IN 3347 01:57:22,480 --> 01:57:25,240 A WORKPLACE SETTING, AND 3348 01:57:25,240 --> 01:57:26,720 DR. CHRISTOPHER IS A PROFESSOR 3349 01:57:26,720 --> 01:57:28,560 AT PACIFIC UNIVERSITY AND THE 3350 01:57:28,560 --> 01:57:31,320 DIRECTOR OF MINDFUL HEALTH AND 3351 01:57:31,320 --> 01:57:32,200 RESILIENCE LABORATORY. 3352 01:57:32,200 --> 01:57:33,760 HIS PRIMARY RESEARCH IS FOCUSED 3353 01:57:33,760 --> 01:57:35,560 ON THE IMPACT OF MINDFULNESS AND 3354 01:57:35,560 --> 01:57:37,560 ITS RELATED CONTEMPLATED 3355 01:57:37,560 --> 01:57:39,000 PRACTICES ENHANCING RESILIENCE 3356 01:57:39,000 --> 01:57:41,760 AND IMPROVING STRESS REACTIVITY 3357 01:57:41,760 --> 01:57:43,720 IN HIGH RISK AND DIVERSE GROUPS. 3358 01:57:43,720 --> 01:57:50,240 HE'S DEVELOPED THE MINDFULNESS 3359 01:57:50,240 --> 01:57:52,040 AND RESILIENCE TRAINING DESIGNED 3360 01:57:52,040 --> 01:57:53,680 TO PREVENT STRESS REACTIVITY AND 3361 01:57:53,680 --> 01:57:55,160 HEALTH OUTCOMES AMONG HIGH 3362 01:57:55,160 --> 01:57:55,800 STRESS COHORTS. 3363 01:57:55,800 --> 01:57:57,680 THEN WE'RE GOING TO TURN THINGS 3364 01:57:57,680 --> 01:58:01,280 OVER TO DR. ZEV ZEV 3365 01:58:01,280 --> 01:58:02,040 SCHUMAN-OLIVIER WHO'S GOING TO 3366 01:58:02,040 --> 01:58:03,920 TELL US ABOUT POPULATION-BASED 3367 01:58:03,920 --> 01:58:05,120 SCREENINGS HE'S DOING IN A 3368 01:58:05,120 --> 01:58:06,200 HEALTHCARE SETTING AND SOME 3369 01:58:06,200 --> 01:58:13,680 RESEARCH HE'S DOING IN THAT 3370 01:58:13,680 --> 01:58:14,200 SPACE. 3371 01:58:14,200 --> 01:58:16,920 CAMBRIDGE HEALTH ALLIANCE AS 3372 01:58:16,920 --> 01:58:18,440 WELL AS AN ASSISTANT PROFESSOR 3373 01:58:18,440 --> 01:58:20,120 IN THE DEPARTMENT OF PSYCHIATRY 3374 01:58:20,120 --> 01:58:21,000 AT HARVARD MEDICAL SCHOOL. 3375 01:58:21,000 --> 01:58:28,760 HE'S THE FOUNDING DIRECTOR OF -H 3376 01:58:28,760 --> 01:58:30,280 SUBSTANCE USE, MENTAL HEALTH 3377 01:58:30,280 --> 01:58:32,360 DISORDERS AND CHRONIC PAIN IN 3378 01:58:32,360 --> 01:58:33,280 BOTH MENTAL HEALTH AND PRIMARY 3379 01:58:33,280 --> 01:58:37,720 CARE SETTINGS. 3380 01:58:37,720 --> 01:58:42,000 OUR FINAL SPEAKER WILL BE 3381 01:58:42,000 --> 01:58:45,600 DR. JUDITH MOSKOWITZ. 3382 01:58:45,600 --> 01:58:47,000 DR. MOSKOWITZ IS A PROFESSOR OF 3383 01:58:47,000 --> 01:58:49,400 MEDICAL SOCIAL SCIENCES AT 3384 01:58:49,400 --> 01:58:51,000 NORTHWESTERN UNIVERSITY FEINBERG 3385 01:58:51,000 --> 01:58:52,000 SCHOOL OF MEDICINE. 3386 01:58:52,000 --> 01:58:55,920 SHE'S THE DIRECT DIRECTOR OH 3387 01:58:55,920 --> 01:58:57,080 AT THE CENTER FOR INTEGRATIVE 3388 01:58:57,080 --> 01:58:58,440 HEALTH AND HER CURRENT RESEARCH 3389 01:58:58,440 --> 01:59:00,160 IS FOCUSED ON UNIQUE ADAPTIVE 3390 01:59:00,160 --> 01:59:02,560 ROLE OF POSITIVE EMOTION IN THE 3391 01:59:02,560 --> 01:59:04,320 PROCESS OF COPING WITH VARIOUS 3392 01:59:04,320 --> 01:59:07,080 TYPES OF HEALTH RELATED AND 3393 01:59:07,080 --> 01:59:08,040 OTHER LIFE STRESSORS. 3394 01:59:08,040 --> 01:59:10,720 SO WE'VE GOT A STAR STUDDED 3395 01:59:10,720 --> 01:59:11,920 PANEL FOR YOU TODAY. 3396 01:59:11,920 --> 01:59:14,960 SO I WANT TO JUST GIVE A VERY 3397 01:59:14,960 --> 01:59:15,520 BRIEF CONTEXT, THINK WE'VE 3398 01:59:15,520 --> 01:59:17,280 TALKED THIS MORNING A LITTLE BIT 3399 01:59:17,280 --> 01:59:20,640 ABOUT STRESS AND HOW CHALLENGING 3400 01:59:20,640 --> 01:59:22,600 THE SITUATION IS GETTING AROUND 3401 01:59:22,600 --> 01:59:27,040 THE WORLD AND HOW MANY STRESSORS 3402 01:59:27,040 --> 01:59:29,000 WE'RE DEALING WITH BUT JUGS TO 3403 01:59:29,000 --> 01:59:31,320 PUT THIS IN CONTEXT, EVEN BEFORE 3404 01:59:31,320 --> 01:59:32,840 THE PANDEMIC THIS IS SOMETHING 3405 01:59:32,840 --> 01:59:34,360 WE WERE TALKING ABOUT. 3406 01:59:34,360 --> 01:59:36,080 OUR STEVEN STRAUSS DISTINGUISHED 3407 01:59:36,080 --> 01:59:39,720 LECTURE FOR COMPLEMENTARY 3408 01:59:39,720 --> 01:59:46,440 THERAPIES WE DO ANNUALLY, ABOUT 3409 01:59:46,440 --> 01:59:48,960 A NATION UNDER PRESSURE AND THE 3410 01:59:48,960 --> 01:59:50,040 PUBLIC HEALTH CONSEQUENCES OF 3411 01:59:50,040 --> 01:59:51,000 STRESS IN AMERICA. 3412 01:59:51,000 --> 01:59:53,560 AND AS WE ARE ALL WELL AWARE, 3413 01:59:53,560 --> 01:59:55,200 THIS HAS JUST GOTTEN WORSE WITH 3414 01:59:55,200 --> 01:59:57,920 THE PANDEMIC, SO MUCH SO THAT 3415 01:59:57,920 --> 01:59:59,120 DR. MURTHY AS SURGEON GENERAL 3416 01:59:59,120 --> 02:00:02,280 HAS JUST ISSUED IN THE LAST FEW 3417 02:00:02,280 --> 02:00:04,240 MONTHS AN ADVISORY ON THE YOUTH 3418 02:00:04,240 --> 02:00:05,880 MENTAL HEALTH CRISIS THAT WE 3419 02:00:05,880 --> 02:00:07,880 HAVE, WHICH HAS BEEN FURTHER 3420 02:00:07,880 --> 02:00:10,480 EXPOSED BY THE COVID-19 3421 02:00:10,480 --> 02:00:10,840 PANDEMIC. 3422 02:00:10,840 --> 02:00:12,600 SO THIS IS JUST A MAJOR ISSUE 3423 02:00:12,600 --> 02:00:14,040 FOR ALL OF US, BUT PARTICULARLY 3424 02:00:14,040 --> 02:00:17,880 THE CHILDREN IN OUR -- IN THE 3425 02:00:17,880 --> 02:00:22,760 U.S. AS WELL AS INTERNATIONALLY. 3426 02:00:22,760 --> 02:00:23,560 MANY OF YOU ARE PROBABLY 3427 02:00:23,560 --> 02:00:24,760 FAMILIAR WITH THESE STATISTICS. 3428 02:00:24,760 --> 02:00:28,360 EARLY ON IN THE PANDEMIC, 3429 02:00:28,360 --> 02:00:30,200 SURVEYS REPORTED THAT 70% OF 3430 02:00:30,200 --> 02:00:33,000 AMERICANS SURVEYED FELT THAT THE 3431 02:00:33,000 --> 02:00:35,240 COVID PANDEMIC WAS AN EXTREME OR 3432 02:00:35,240 --> 02:00:36,920 SEVERE CRISIS AND NEARLY TWO 3433 02:00:36,920 --> 02:00:38,240 THIRDS SAID THEY HAD REPORTED 3434 02:00:38,240 --> 02:00:40,400 INCREASED STRESS, ANXIETY OR 3435 02:00:40,400 --> 02:00:42,080 DEPRESSION, AND THAT 3436 02:00:42,080 --> 02:00:43,480 COVID-RELATED STRESSORS WERE 3437 02:00:43,480 --> 02:00:45,000 INTERFERING MODERATELY, SEVERELY 3438 02:00:45,000 --> 02:00:47,120 OR OVERWHELMINGLY IN THEIR 3439 02:00:47,120 --> 02:00:47,720 LIVES. 3440 02:00:47,720 --> 02:00:49,800 TWO YEARS LATER, WE HAVEN'T 3441 02:00:49,800 --> 02:00:51,680 GOTTEN MUCH BETTER. 3442 02:00:51,680 --> 02:00:55,840 IN MARCH OF 2022, THE AMERICAN 3443 02:00:55,840 --> 02:00:56,360 PSYCHOLOGICAL ASSOCIATION 3444 02:00:56,360 --> 02:00:59,880 RELEASED A SERIES OF DATA AND 3445 02:00:59,880 --> 02:01:02,040 STATISTICS LOOKING AT STRESS IN 3446 02:01:02,040 --> 02:01:04,720 AMERICA, MONEY, INFLATION AND 3447 02:01:04,720 --> 02:01:07,320 THE WAR THAT'S GOING ON IN THE 3448 02:01:07,320 --> 02:01:08,280 UKRAINE PILE ON TO A NATION 3449 02:01:08,280 --> 02:01:09,840 THAT'S STUCK IN SORT OF THIS 3450 02:01:09,840 --> 02:01:11,800 CONTINUED SURVIVAL MODE. 3451 02:01:11,800 --> 02:01:14,960 A FEW GRAPHICS FROM THEIR 3452 02:01:14,960 --> 02:01:16,640 INFORMATION THAT THE DIFFERENT 3453 02:01:16,640 --> 02:01:18,480 SOURCES OF STRESS, 87% OF 3454 02:01:18,480 --> 02:01:20,480 AMERICANS SAY THAT THE RISING 3455 02:01:20,480 --> 02:01:22,680 COST OF INFLATION IS A MAJOR 3456 02:01:22,680 --> 02:01:24,760 STRESSOR. 3457 02:01:24,760 --> 02:01:25,720 GLOBAL UNCERTAINTY, THE WAR IN 3458 02:01:25,720 --> 02:01:27,160 RUSSIA AND POTENTIAL RETALIATION 3459 02:01:27,160 --> 02:01:28,760 ARE ALL MAJOR STRESSORS WITH 3460 02:01:28,760 --> 02:01:31,880 MORE THAN 80% OF INDIVIDUALS 3461 02:01:31,880 --> 02:01:34,040 REPORTING THESE AS STRESSORS. 3462 02:01:34,040 --> 02:01:35,600 OVER TWO THIRDS HERE AGAIN 3463 02:01:35,600 --> 02:01:36,200 REPORT THAT THEIR LIVES HAVE 3464 02:01:36,200 --> 02:01:38,080 BEEN FOREVER CHANGED BY THE 3465 02:01:38,080 --> 02:01:40,720 PANDEMIC. 3466 02:01:40,720 --> 02:01:43,040 AND THAT THEY CONSTANTLY FEAR 3467 02:01:43,040 --> 02:01:46,400 THE NEXT VARIANT THAT MAY BE 3468 02:01:46,400 --> 02:01:46,640 COMING. 3469 02:01:46,640 --> 02:01:48,280 AND WHEN YOU LOOK AT THE 3470 02:01:48,280 --> 02:01:50,120 DIFFERENT ECONOMIC STRESSORS BY 3471 02:01:50,120 --> 02:01:51,880 RAISE AND ETHNICITY, YOU SEE 3472 02:01:51,880 --> 02:01:54,080 THAT THEY DO VARY SOMEWHAT. 3473 02:01:54,080 --> 02:01:56,240 I THINK WHAT'S VERY INTERESTING 3474 02:01:56,240 --> 02:01:57,920 HERE IS HOUSING IN PARTICULAR, 3475 02:01:57,920 --> 02:01:59,800 AND HOW MUCH HOUSING AS A 3476 02:01:59,800 --> 02:02:01,120 STRESSOR AND WHERE YOU'RE GOING 3477 02:02:01,120 --> 02:02:02,960 TO LIVE DIFFERS BY SOMEONE'S 3478 02:02:02,960 --> 02:02:04,720 BACKGROUND IN TERMS OF THEIR 3479 02:02:04,720 --> 02:02:06,800 RACE AND ETHNICITY WITH ONLY 45% 3480 02:02:06,800 --> 02:02:08,320 OF WHITE ADULTS REPORTING THIS 3481 02:02:08,320 --> 02:02:11,160 AS A STRESSOR VERSUS 57 TO 62% 3482 02:02:11,160 --> 02:02:13,440 OF BLACK AND LATINO ADULTS. 3483 02:02:13,440 --> 02:02:15,080 SO THIS CONTINUES TO BE A MAJOR 3484 02:02:15,080 --> 02:02:18,280 ISSUE AND SO THE QUESTION IS, 3485 02:02:18,280 --> 02:02:19,920 WHAT DO WE DO ABOUT IT AND HOW 3486 02:02:19,920 --> 02:02:20,800 DO WE ADDRESS THIS? 3487 02:02:20,800 --> 02:02:22,680 SO THIS IS WHERE SORT OF OUR 3488 02:02:22,680 --> 02:02:23,760 FRAMEWORK IN THINKING ABOUT HOW 3489 02:02:23,760 --> 02:02:26,600 DO WE FUND RESEARCH IN CLINICAL 3490 02:02:26,600 --> 02:02:27,920 RESEARCH TO BE ABLE TO ADDRESS 3491 02:02:27,920 --> 02:02:30,960 SOME OF THESE STRESSORS. 3492 02:02:30,960 --> 02:02:32,720 AND WHAT I'M GOING TO SHARE WITH 3493 02:02:32,720 --> 02:02:34,600 YOU IS OUR FRAMEWORK IN HOW WE 3494 02:02:34,600 --> 02:02:37,400 THINK ABOUT THIS, BUT THIS IS 3495 02:02:37,400 --> 02:02:38,200 BEING ADDRESSED IN A NUMBER OF 3496 02:02:38,200 --> 02:02:38,840 DIFFERENT WAYS. 3497 02:02:38,840 --> 02:02:42,680 FOR EXAMPLE, THE CDC EVEN 3498 02:02:42,680 --> 02:02:44,000 RELEASED ON THE LEFT HERE A 3499 02:02:44,000 --> 02:02:45,400 GENERAL WAY OF HOW TO CARE FOR 3500 02:02:45,400 --> 02:02:46,840 YOURSELF DURING THE PANDEMIC. 3501 02:02:46,840 --> 02:02:48,920 THINGS TO DO TO KEEP SOCIALLY 3502 02:02:48,920 --> 02:02:50,120 CONNECTED AND KEEP YOURSELF 3503 02:02:50,120 --> 02:02:50,640 HEALTHY. 3504 02:02:50,640 --> 02:02:52,080 AND THEN IF YOU GO ON THEIR 3505 02:02:52,080 --> 02:02:53,280 WEBSITE, THEY HAVE ONE 3506 02:02:53,280 --> 02:02:56,480 SPECIFICALLY FOR OLDER ADULTS, 3507 02:02:56,480 --> 02:02:57,360 SPECIFICALLY FOR FIRST LINE 3508 02:02:57,360 --> 02:02:58,760 WORKERS AND FOR STUDENTS AND FOR 3509 02:02:58,760 --> 02:02:59,960 YOUNG PEOPLE, WHERE THEY'VE 3510 02:02:59,960 --> 02:03:01,080 TARGETED THESE MESSAGES TO TRY 3511 02:03:01,080 --> 02:03:02,280 TO REALLY HELP PEOPLE THINK 3512 02:03:02,280 --> 02:03:03,920 ABOUT HOWL DO YOU TAKE CARE OF 3513 02:03:03,920 --> 02:03:06,640 YOURSELF DURING THESE TIMES. 3514 02:03:06,640 --> 02:03:08,280 AND OUR ROLE HERE AT NCCIH IS, 3515 02:03:08,280 --> 02:03:11,920 HOW DO WE FUND THE RESEARCH TO 3516 02:03:11,920 --> 02:03:13,200 GIVE YOU THE EVIDENCE THAT DOING 3517 02:03:13,200 --> 02:03:14,400 THESE THINGS WILL ACTUALLY 3518 02:03:14,400 --> 02:03:17,000 REDUCE YOUR STRESS? 3519 02:03:17,000 --> 02:03:18,200 AND THAT'S WHERE SORT OF OUR 3520 02:03:18,200 --> 02:03:20,680 FRAMEWORK COMES INTO MIND. 3521 02:03:20,680 --> 02:03:22,320 NOT ONLY MECHANISTICALLY HOW DO 3522 02:03:22,320 --> 02:03:23,440 THESE INTERVENTIONS IMPACT 3523 02:03:23,440 --> 02:03:24,640 STRESS IN OUR LIFETIME, BUT AS 3524 02:03:24,640 --> 02:03:26,800 WE THINK ABOUT DEVELOPING THESE 3525 02:03:26,800 --> 02:03:28,040 INTERVENTIONS, HOW DO WE REFINE 3526 02:03:28,040 --> 02:03:29,760 THEM, HOW DO WE OPTIMIZE THEM, 3527 02:03:29,760 --> 02:03:31,720 LOW DO WE TEST WHETHER THEY 3528 02:03:31,720 --> 02:03:33,280 WORK, HOW DO WE THEN GET THEM 3529 02:03:33,280 --> 02:03:35,680 OUT INTO CLINICAL PRACTICE, INTO 3530 02:03:35,680 --> 02:03:37,320 EITHER HEALTHCARE SETTINGS, 3531 02:03:37,320 --> 02:03:38,600 COMMUNITY-BASED SETTINGS, OR 3532 02:03:38,600 --> 02:03:42,200 EVEN EMPLOYER-BASED SETTINGS. 3533 02:03:42,200 --> 02:03:43,560 I THINK WE'VE SHARED WITH 3534 02:03:43,560 --> 02:03:44,640 COUNCIL AT PREVIOUS MEETINGS 3535 02:03:44,640 --> 02:03:46,760 THAT WE DO HAVE FUNDING 3536 02:03:46,760 --> 02:03:47,960 OPPORTUNITIES FOR THIS WHOLE 3537 02:03:47,960 --> 02:03:51,000 RANGE OF RESEARCH QUESTIONS FROM 3538 02:03:51,000 --> 02:03:53,160 THE VERY EARLY FEASIBILITY WORK 3539 02:03:53,160 --> 02:03:55,480 TO THE EFFICACY STUDIES AND 3540 02:03:55,480 --> 02:03:56,240 EVENTUALLY INTO THOSE 3541 02:03:56,240 --> 02:03:57,640 DISSEMINATION AND IMPLEMENTATION 3542 02:03:57,640 --> 02:04:00,280 SCIENCE FRAMEWORKS, BOTH FOR THE 3543 02:04:00,280 --> 02:04:02,360 INTERVENTIONS THAT HAVE 3544 02:04:02,360 --> 02:04:05,560 PSYCHOLOGICAL, BEHAVIORAL AND 3545 02:04:05,560 --> 02:04:07,400 PHYSICAL UNDER PINNINGS TO THEM 3546 02:04:07,400 --> 02:04:08,720 WITH MIND AND BODY INTERVENTIONS 3547 02:04:08,720 --> 02:04:09,920 BUT ALSO FOR OUR NATURAL 3548 02:04:09,920 --> 02:04:11,320 PRODUCTS, WE HAVE FUNDING 3549 02:04:11,320 --> 02:04:13,840 MECHANISMS ACROSS THE SPECTRUM, 3550 02:04:13,840 --> 02:04:16,760 AND CERTAINLY WE'RE WELL AWARE 3551 02:04:16,760 --> 02:04:17,840 OF DIFFERENT NATURAL PRODUCTS 3552 02:04:17,840 --> 02:04:19,400 USED IN DIFFERENT COMMUNITIES TO 3553 02:04:19,400 --> 02:04:20,720 HELP MANAGE STRESS, SO THERE ARE 3554 02:04:20,720 --> 02:04:21,800 OPPORTUNITIES FOR THESE AS WELL, 3555 02:04:21,800 --> 02:04:25,320 LOOKING AT THE IMPACT IN BUY 3556 02:04:25,320 --> 02:04:26,600 BIOLOGICAL SIGNATURES AND 3557 02:04:26,600 --> 02:04:29,720 EVENTUALLY MOVING INTO EFFICACY 3558 02:04:29,720 --> 02:04:30,560 STUDIES. 3559 02:04:30,560 --> 02:04:32,840 AS WE'VE GONE ALONG OVER TIME IN 3560 02:04:32,840 --> 02:04:34,200 DEVELOPING OUR FUNDING 3561 02:04:34,200 --> 02:04:35,640 OPPORTUNITIES, WE'VE TRIED TO 3562 02:04:35,640 --> 02:04:37,120 STREAMLINE THESE SO THAT WE CAN 3563 02:04:37,120 --> 02:04:39,440 GET TO THOSE EFFICACY AND 3564 02:04:39,440 --> 02:04:40,520 EFFECTIVENESS STUDIES AS QUICKLY 3565 02:04:40,520 --> 02:04:42,840 AS POSSIBLE, BUT WE UNDERSTAND 3566 02:04:42,840 --> 02:04:43,600 SOMETIMES THE PRELIMINARY DATA 3567 02:04:43,600 --> 02:04:45,440 MAY NOT BE THERE YET TO ACTUALLY 3568 02:04:45,440 --> 02:04:48,960 JUSTIFY DOING THAT FULL SCALE 3569 02:04:48,960 --> 02:04:49,560 TRIAL. 3570 02:04:49,560 --> 02:04:51,160 THAT'S WHY WE PROVIDE A VARIETY 3571 02:04:51,160 --> 02:04:52,960 OF LITTLE ENTRY POINTS INTO THAT 3572 02:04:52,960 --> 02:04:55,080 FRAMEWORK FOR DOING THESE TYPES 3573 02:04:55,080 --> 02:04:56,040 OF CLINICAL TRIALS. 3574 02:04:56,040 --> 02:04:58,600 WE WANT TO MOVE PAST THE 3575 02:04:58,600 --> 02:05:01,400 FEASIBILITY WORK AND WE'VE 3576 02:05:01,400 --> 02:05:02,640 ADDRESSED THE PRELIMINARY DATA 3577 02:05:02,640 --> 02:05:04,040 REQUIREMENTS AND ENCOURAGING OUR 3578 02:05:04,040 --> 02:05:05,360 INVESTIGATORS TO LEVERAGE THE 3579 02:05:05,360 --> 02:05:06,440 PUBLISHED LITERATURE AND MOVE ON 3580 02:05:06,440 --> 02:05:08,720 TO THE NEXT STAGE OF RESEARCH. 3581 02:05:08,720 --> 02:05:09,840 AND I'M GOING TO SHOW YOU IN 3582 02:05:09,840 --> 02:05:12,120 JUST A MINUTE HOW WE HAVE 3583 02:05:12,120 --> 02:05:13,520 FUNDING OPPORTUNITIES ACROSS THE 3584 02:05:13,520 --> 02:05:15,880 ENTIRE FRAMEWORK FOR YOU TO 3585 02:05:15,880 --> 02:05:16,160 CONSIDER. 3586 02:05:16,160 --> 02:05:18,920 AND HERE'S AN EXAMPLE OF THAT. 3587 02:05:18,920 --> 02:05:20,160 WHERE WE'VE PLUGGED IN ALL OF 3588 02:05:20,160 --> 02:05:22,120 THE VARIOUS FUNDING 3589 02:05:22,120 --> 02:05:22,840 OPPORTUNITIES, AND YOU CAN FIND 3590 02:05:22,840 --> 02:05:25,680 THESE ON OUR WEBSITE IF YOU JUST 3591 02:05:25,680 --> 02:05:27,000 SEARCH ON OUR WEBSITE FOR 3592 02:05:27,000 --> 02:05:29,080 CLINICAL RESEARCH FUNDING 3593 02:05:29,080 --> 02:05:30,280 OPPORTUNITIES, THERE'S A LIST OF 3594 02:05:30,280 --> 02:05:31,400 ALL OF THESE VARIOUS FUNDING 3595 02:05:31,400 --> 02:05:32,160 OPPORTUNITIES AND SORT OF WHERE 3596 02:05:32,160 --> 02:05:35,520 THEY FIT IN AND WHAT STAGE OF 3597 02:05:35,520 --> 02:05:36,080 RESEARCH THEY'RE APPROPRIATE 3598 02:05:36,080 --> 02:05:38,520 FOR. 3599 02:05:38,520 --> 02:05:39,920 I DO WANT TO MENTION ONE THING 3600 02:05:39,920 --> 02:05:42,280 THAT WAS PRESENTED IN A PREVIOUS 3601 02:05:42,280 --> 02:05:43,320 CONFERENCE WE HAD BACK IN 3602 02:05:43,320 --> 02:05:44,760 SEPTEMBER BY DR. LINDA COLLINS, 3603 02:05:44,760 --> 02:05:47,600 WHO'S AT NYU. 3604 02:05:47,600 --> 02:05:48,920 SHE'S DONE A LOT OF WORK IN 3605 02:05:48,920 --> 02:05:51,760 THINKING ABOUT HOW DO WE 3606 02:05:51,760 --> 02:05:52,640 OPTIMIZE INTERVENTIONS AND USING 3607 02:05:52,640 --> 02:05:54,280 SOME ADAPTIVE DESIGNS TO DO 3608 02:05:54,280 --> 02:05:56,760 THAT, AND SHE JUST RECENTLY HAS 3609 02:05:56,760 --> 02:05:57,880 SORT OF STARTED TALKING ABOUT A 3610 02:05:57,880 --> 02:06:00,400 NEW ACRONYM THAT SHE'S USING 3611 02:06:00,400 --> 02:06:01,720 CALLED EASE, WHICH IS, AS WE 3612 02:06:01,720 --> 02:06:04,120 THINK ABOUT DESIGNING AND 3613 02:06:04,120 --> 02:06:05,200 EVENTUALLY TESTING 3614 02:06:05,200 --> 02:06:06,840 INTERVENTIONS, IT'S A BALANCING 3615 02:06:06,840 --> 02:06:08,160 ACT BETWEEN HOW EFFECTIVE ARE 3616 02:06:08,160 --> 02:06:09,240 THOSE INTERVENTIONS, WHICH IS 3617 02:06:09,240 --> 02:06:12,760 WHAT WE ALWAYS TRY TO MAXIMIZE, 3618 02:06:12,760 --> 02:06:23,240 BUT THAT WE ALSO -- I OFTEN 3619 02:06:24,600 --> 02:06:26,920 THINK OF THE SCALABILITY ELEMENT 3620 02:06:26,920 --> 02:06:28,120 IN BEING -- CAN IT BE USED IN 3621 02:06:28,120 --> 02:06:30,280 DIFFERENT PLACES, CAN YOU SHIFT 3622 02:06:30,280 --> 02:06:32,720 IT OR CHANGE IT OR HAVE SOME 3623 02:06:32,720 --> 02:06:34,160 FLEXIBILITY IN IT SO THAT IT CAN 3624 02:06:34,160 --> 02:06:36,000 BE CUSTOMIZED OR TAILORED TO 3625 02:06:36,000 --> 02:06:37,440 SPECIFIC POPULATIONS OR MAYBE 3626 02:06:37,440 --> 02:06:40,360 LESS RESOURCE INTENSIVE 3627 02:06:40,360 --> 02:06:41,400 ENVIRONMENTS, OR MAYBE THEY 3628 02:06:41,400 --> 02:06:42,160 DON'T HAVE THE SAME 3629 02:06:42,160 --> 02:06:42,720 INFRASTRUCTURE. 3630 02:06:42,720 --> 02:06:44,680 SO THINKING ABOUT THAT UP FRONT 3631 02:06:44,680 --> 02:06:46,960 AS WE DESIGN AND OPTIMIZE AND 3632 02:06:46,960 --> 02:06:49,400 REFINE OUR INTERVENTIONS IS 3633 02:06:49,400 --> 02:06:50,800 REALLY IMPORTANT SO THAT AS WE 3634 02:06:50,800 --> 02:06:52,080 TEST INTERVENTIONS AND KNOW 3635 02:06:52,080 --> 02:06:53,000 WHETHER THEY WORK, THAT THEY 3636 02:06:53,000 --> 02:06:54,440 ACTUALLY CAN BE SCALED UP AND 3637 02:06:54,440 --> 02:06:57,920 SCALED OUT. 3638 02:06:57,920 --> 02:06:59,880 SO AS WE THINK HERE AT NCCIH 3639 02:06:59,880 --> 02:07:01,440 ABOUT IMPACTFUL CLINICAL TRIALS, 3640 02:07:01,440 --> 02:07:03,280 THERE'S A FEW THINGS THAT WE 3641 02:07:03,280 --> 02:07:03,960 THINK ABOUT. 3642 02:07:03,960 --> 02:07:06,360 AS WE MOVE TOWARDS EFFICACY AND 3643 02:07:06,360 --> 02:07:07,680 DOING EFFICACY STUDIES ON 3644 02:07:07,680 --> 02:07:08,760 NATURAL PRODUCTS, WE WANT TO 3645 02:07:08,760 --> 02:07:12,720 KNOW THAT WE HAVE AN ACTIVE 3646 02:07:12,720 --> 02:07:14,520 BIOLOGICAL SIGNATURE THAT THE 3647 02:07:14,520 --> 02:07:16,680 NATURAL PRODUCT CAN REPRODUCIBLY 3648 02:07:16,680 --> 02:07:18,440 AFFECT A POTENTIAL MECHANISM AND 3649 02:07:18,440 --> 02:07:19,640 THAT HELPS US KNOW THAT WE'VE 3650 02:07:19,640 --> 02:07:21,200 GOT AN ACTIVE COMPOUND AND WE'RE 3651 02:07:21,200 --> 02:07:24,120 READY TO MOVE INTO EFFICACY 3652 02:07:24,120 --> 02:07:24,880 STUDIES. 3653 02:07:24,880 --> 02:07:26,320 SIMILARLY ON THE MIND AND BODY 3654 02:07:26,320 --> 02:07:28,000 SIDE OF THINGS AND OUR 3655 02:07:28,000 --> 02:07:29,840 INTERVENTIONS ON THAT SIDE, WE 3656 02:07:29,840 --> 02:07:31,040 WANT TO MAKE SURE WE HAVE 3657 02:07:31,040 --> 02:07:32,040 INTERVENTIONS THAT ARE FEASIBLE, 3658 02:07:32,040 --> 02:07:33,120 PEOPLE CAN DO THEM, AND THAT 3659 02:07:33,120 --> 02:07:35,200 THEY CAN BE DELIVERED WITH 3660 02:07:35,200 --> 02:07:36,160 FIDELITY ACROSS SITES SO THAT 3661 02:07:36,160 --> 02:07:37,920 WHEN WE GO TO THAT MULTISITE 3662 02:07:37,920 --> 02:07:38,920 TRIAL, WE KNOW THAT EVERYBODY IS 3663 02:07:38,920 --> 02:07:40,480 GETTING THE SAME OR VERY CLOSE 3664 02:07:40,480 --> 02:07:42,160 TO THE SAME INTERVENTION, WE 3665 02:07:42,160 --> 02:07:43,360 KNOW WHAT ARE THE CORE 3666 02:07:43,360 --> 02:07:44,720 COMPONENTS AND WHAT CAN MAYBE BE 3667 02:07:44,720 --> 02:07:46,520 ALTERED BY SITE. 3668 02:07:46,520 --> 02:07:48,240 AND THEN WE'RE READY TO MOVE 3669 02:07:48,240 --> 02:07:50,760 INTO THOSE EFFICACY IN 3670 02:07:50,760 --> 02:07:52,720 EFFECTIVENESS STUDIES. 3671 02:07:52,720 --> 02:07:54,400 AND ONCE WE KNOW WHETHER 3672 02:07:54,400 --> 02:07:55,800 INTERVENTIONS WORK OR NOT, 3673 02:07:55,800 --> 02:07:57,560 WHETHER THEY HAVE EFFICACY OR 3674 02:07:57,560 --> 02:07:59,160 EFFECTIVENESS, THEN WE'RE READY 3675 02:07:59,160 --> 02:08:01,040 TO DO THOSE PRAGMATIC TRIALS. 3676 02:08:01,040 --> 02:08:02,440 HOW DO WE GET THEM INTO THE 3677 02:08:02,440 --> 02:08:03,560 HEALTHCARE SETTING OR 3678 02:08:03,560 --> 02:08:04,440 COMMUNITY-BASED APPROACHES, 3679 02:08:04,440 --> 02:08:09,800 COMMUNITY SETTINGS, THE 3680 02:08:09,800 --> 02:08:10,560 WORKPLACE SETTINGS OR OTHER 3681 02:08:10,560 --> 02:08:11,080 PLACES LIKE THAT. 3682 02:08:11,080 --> 02:08:14,720 AND SO IN REALITY, TRIALS ALL 3683 02:08:14,720 --> 02:08:16,360 ALONG THIS CONTINUUM CAN BE 3684 02:08:16,360 --> 02:08:17,040 IMPACTFUL BECAUSE KNOWING 3685 02:08:17,040 --> 02:08:20,760 WHETHER WE HAVE A REPRODUCIBLE, 3686 02:08:20,760 --> 02:08:21,520 BIOLOGICAL SIGNATURE TELLS US 3687 02:08:21,520 --> 02:08:23,360 WHEN WE'RE READY TO MOVE TO THAT 3688 02:08:23,360 --> 02:08:24,720 NEXT STUDY, SO THAT'S A REALLY 3689 02:08:24,720 --> 02:08:25,560 IMPORTANT STEP. 3690 02:08:25,560 --> 02:08:26,840 DETERMINING THE FEASIBILITY AND 3691 02:08:26,840 --> 02:08:27,960 THE FIDELITY OF THESE 3692 02:08:27,960 --> 02:08:29,200 INTERVENTIONS CAN BE REALLY 3693 02:08:29,200 --> 02:08:30,400 IMPACTFUL, BECAUSE IT CAN SHIFT 3694 02:08:30,400 --> 02:08:31,720 AND CHANGE HOW THE INTERVENTION 3695 02:08:31,720 --> 02:08:34,040 IS DELIVERED AND HOW IT'S 3696 02:08:34,040 --> 02:08:34,800 DESIGNED SO IT HAS THE 3697 02:08:34,800 --> 02:08:36,080 OPPORTUNITY TO BE TESTED AS WELL 3698 02:08:36,080 --> 02:08:39,480 AS SCALED UP EVENTUALLY. 3699 02:08:39,480 --> 02:08:41,120 SO WHAT WILL SUCCESS LOOK LIKE 3700 02:08:41,120 --> 02:08:42,800 FOR US? 3701 02:08:42,800 --> 02:08:44,320 THAT WE'LL HAVE A RANGE OF 3702 02:08:44,320 --> 02:08:46,080 TRIALS ACROSS THE FRAMEWORK IN 3703 02:08:46,080 --> 02:08:47,080 ALL OF THESE DIFFERENT 3704 02:08:47,080 --> 02:08:47,840 APPROACHES. 3705 02:08:47,840 --> 02:08:49,560 THAT THINGS MOVE ALONG THAT 3706 02:08:49,560 --> 02:08:51,120 FRAMEWORK SUCH THAT WHEN WE KNOW 3707 02:08:51,120 --> 02:08:52,400 THAT THEY'RE FEASIBLE, THAT WE 3708 02:08:52,400 --> 02:08:53,840 KNOW THAT THEY'RE EFFECTIVE, 3709 02:08:53,840 --> 02:08:55,600 THEY MOVE INTO CLINICAL PRACTICE 3710 02:08:55,600 --> 02:08:58,920 OR INTO COMMUNITY OR WORKPLACE 3711 02:08:58,920 --> 02:08:59,560 SETTINGS. 3712 02:08:59,560 --> 02:09:00,760 AND THAT EVENTUALLY, THE TRIALS 3713 02:09:00,760 --> 02:09:02,120 THAT WE'RE SUPPORTING ARE 3714 02:09:02,120 --> 02:09:03,600 ACTUALLY INCORPORATED INTO 3715 02:09:03,600 --> 02:09:05,440 GUIDELINES THAT THEY SET 3716 02:09:05,440 --> 02:09:06,840 HEALTHCARE POLICY DECISIONS, 3717 02:09:06,840 --> 02:09:09,240 THEY INFORM PAYORS ABOUT WHAT 3718 02:09:09,240 --> 02:09:10,400 INTERVENTIONS SHOULD BE COVERED 3719 02:09:10,400 --> 02:09:11,600 AND MADE AVAILABLE TO THE 3720 02:09:11,600 --> 02:09:14,960 BROADER COMMUNITY. 3721 02:09:14,960 --> 02:09:16,640 SO I THINK THAT IS MY LAST 3722 02:09:16,640 --> 02:09:17,960 SLIDE, AND I THINK WHAT I'M 3723 02:09:17,960 --> 02:09:20,560 GOING TO DO NOW IS TURN THINGS 3724 02:09:20,560 --> 02:09:23,040 OVER TO DR. MICHAEL CHRISTOPHER 3725 02:09:23,040 --> 02:09:24,160 TO TELL US A LITTLE BIT ABOUT 3726 02:09:24,160 --> 02:09:25,280 SOME OF THE EXCITING WORK THAT 3727 02:09:25,280 --> 02:09:32,160 HE IS DOING UP AT PACIFIC 3728 02:09:32,160 --> 02:09:32,480 UNIVERSITY. 3729 02:09:32,480 --> 02:09:33,920 >> THANK YOU, VERY MUCH, 3730 02:09:33,920 --> 02:09:34,200 DR. WEBER. 3731 02:09:34,200 --> 02:09:35,000 THANK YOU VERY MUCH TO THE 3732 02:09:35,000 --> 02:09:36,320 COUNCIL FOR HAVING ME HERE 3733 02:09:36,320 --> 02:09:36,520 TODAY. 3734 02:09:36,520 --> 02:09:45,720 IT AN HONOR FOR ME TO . 3735 02:09:45,720 --> 02:09:47,960 SO I'M GOING TO START OFF WITH A 3736 02:09:47,960 --> 02:09:49,480 QUICK STORY, I PROMISE I'LL KEEP 3737 02:09:49,480 --> 02:09:50,880 IT VERY QUICK. 3738 02:09:50,880 --> 02:09:52,000 THIS IS A DETECTIVE FROM THE 3739 02:09:52,000 --> 02:09:53,280 HILLSBOROUGH POLICE DEPARTMENT. 3740 02:09:53,280 --> 02:09:54,840 BEFORE HE WAS SHINY, HAPPY 3741 02:09:54,840 --> 02:10:01,000 SMILING ON THE COVER OF "LIFE" 3742 02:10:01,000 --> 02:10:02,440 MAGAZINE, HE WAS IN 3743 02:10:02,440 --> 02:10:06,240 HILLSBOROUGH, OREGON, AND -- 3744 02:10:06,240 --> 02:10:07,240 BURNED OUT AND STRESSED, I DON'T 3745 02:10:07,240 --> 02:10:08,680 WANT TO BE A POLICE OFFICER 3746 02:10:08,680 --> 02:10:09,680 ANYMORE, I'M DEPRESSED AND MY 3747 02:10:09,680 --> 02:10:10,760 COLLEAGUES ARE JUST LIKE ME, 3748 02:10:10,760 --> 02:10:11,960 WE'RE ALL BURNED OUT, WE'RE 3749 02:10:11,960 --> 02:10:13,720 STRESSED, WE JUST CAN'T DO THIS 3750 02:10:13,720 --> 02:10:14,600 WORK ANYMORE. 3751 02:10:14,600 --> 02:10:15,800 HE HAD READ A LITTLE BIT OF MY 3752 02:10:15,800 --> 02:10:17,840 WORK WE WERE DOING IN 3753 02:10:17,840 --> 02:10:18,280 MINDFULNESS. 3754 02:10:18,280 --> 02:10:20,160 HE SAID I TRIED MEDITATION MAYBE 3755 02:10:20,160 --> 02:10:20,680 LIKE 20 YEARS AGO. 3756 02:10:20,680 --> 02:10:22,640 I DON'T KNOW IF THIS MINDFULNESS 3757 02:10:22,640 --> 02:10:24,040 STUFF IS SORT OF THAT SAME 3758 02:10:24,040 --> 02:10:25,240 THING, BUT I NEED SOMETHING. 3759 02:10:25,240 --> 02:10:27,200 I JUST NEED -- SOMETHING HAS TO 3760 02:10:27,200 --> 02:10:28,120 CHANGE. 3761 02:10:28,120 --> 02:10:32,360 SO WE ENROLLED HIM IN OUR 8-WEEK 3762 02:10:32,360 --> 02:10:34,000 PROGRAM AND TO USE RICH'S 3763 02:10:34,000 --> 02:10:36,160 LANGUAGE, HE DRANK THE KOOL-AID. 3764 02:10:36,160 --> 02:10:38,040 HE CALLED IT LIFE CHANGING. 3765 02:10:38,040 --> 02:10:39,560 RICH IS A VERY DYNAMIC GUY, SO 3766 02:10:39,560 --> 02:10:41,880 FOR HIM, IT WAS NOT ONLY LIFE 3767 02:10:41,880 --> 02:10:43,080 CHANGING FOR HIM. 3768 02:10:43,080 --> 02:10:44,920 IN HIS PERSPECTIVE, LIKE EVERY 3769 02:10:44,920 --> 02:10:46,480 POLICE OFFICER IN THE WORLD 3770 02:10:46,480 --> 02:10:47,480 NEEDED TO DO MINDFULNESS. 3771 02:10:47,480 --> 02:10:49,880 THEY NEEDED TO GET INVOLVED IN A 3772 02:10:49,880 --> 02:10:51,480 MINDFULNESS TRAINING. 3773 02:10:51,480 --> 02:10:53,240 SO THAT'S A QUICK BACK STORY OF 3774 02:10:53,240 --> 02:10:55,400 HOW THIS PROGRAM AND RESEARCH 3775 02:10:55,400 --> 02:10:58,880 GOT STARTED, WITH RICH'S 3776 02:10:58,880 --> 02:10:59,280 PARTNERSHIP. 3777 02:10:59,280 --> 02:11:00,600 SO THIS IS RICH AND I SITTING 3778 02:11:00,600 --> 02:11:01,560 DOWN, KIND OF FIGURING OUT FROM 3779 02:11:01,560 --> 02:11:03,680 THE BEGINNING, WHAT DO WE REALLY 3780 02:11:03,680 --> 02:11:04,320 WANT TO ACCOMPLISH HERE? 3781 02:11:04,320 --> 02:11:05,920 SO AGAIN FOR RICH, IT WAS THAT 3782 02:11:05,920 --> 02:11:08,520 THIS IS REALLY IMPROVING MENTAL 3783 02:11:08,520 --> 02:11:10,440 HEALTH, PHYSICAL HEALTH, THE 3784 02:11:10,440 --> 02:11:12,120 THINGS THAT HE EXPERIENCED. 3785 02:11:12,120 --> 02:11:14,760 WE KNEW A GOOD DEAL OF RESEARCH 3786 02:11:14,760 --> 02:11:16,240 ON THAT. 3787 02:11:16,240 --> 02:11:18,600 I KIND OF CAME TO THIS AS NOT A 3788 02:11:18,600 --> 02:11:20,200 LAW ENFORCEMENT OFFICER BUT A 3789 02:11:20,200 --> 02:11:22,960 SCIENTIST IN A BACKGROUND OF C 3790 02:11:22,960 --> 02:11:25,600 VPR AND COMMUNITY METHODS, ALSO 3791 02:11:25,600 --> 02:11:26,880 REALLY INTERESTED IN THE IMPACT 3792 02:11:26,880 --> 02:11:29,760 THIS CAN HAVE ON OUR COMMUNITIES 3793 02:11:29,760 --> 02:11:30,720 AND COMMUNITY POLICING. 3794 02:11:30,720 --> 02:11:33,480 IT WAS AROUND THIS TIME THAT 3795 02:11:33,480 --> 02:11:34,240 UNFORTUNATELY MICHAEL BROWN OF 3796 02:11:34,240 --> 02:11:35,680 FERGUSON WAS KILLED BY POLICE 3797 02:11:35,680 --> 02:11:37,400 THERE, AND WE THOUGHT MAYBE THIS 3798 02:11:37,400 --> 02:11:40,040 WAS ALSO NOT ONLY A WAY TO 3799 02:11:40,040 --> 02:11:41,000 IMPROVE POLICING IN GENERAL BUT 3800 02:11:41,000 --> 02:11:42,760 TO LOOK AT SOME OF THOSE VIOLENT 3801 02:11:42,760 --> 02:11:44,520 OUTCOMES THAT ARE OFTEN THE 3802 02:11:44,520 --> 02:11:46,720 RESULT OF STRESS BASED OR 3803 02:11:46,720 --> 02:11:47,920 OFFICERS BEING OVERLY STRESS AND 3804 02:11:47,920 --> 02:11:48,880 MAKING POOR DECISIONS. 3805 02:11:48,880 --> 02:11:51,840 SO WE ENGAGED BOTH OF US IN THIS 3806 02:11:51,840 --> 02:11:52,960 CULTURAL IMMERSION. 3807 02:11:52,960 --> 02:11:54,600 FOR ME AND MY LAB IT WAS DOING 3808 02:11:54,600 --> 02:11:56,120 THINGS LIKE RIDE-ALONGS, GOING 3809 02:11:56,120 --> 02:11:57,320 TO BRIEFINGS, GETTING A BETTER 3810 02:11:57,320 --> 02:11:58,840 SENSE OF THAT CULTURE, AND FOR 3811 02:11:58,840 --> 02:12:01,160 RICH AND SOME OF THESE 3812 02:12:01,160 --> 02:12:03,000 COLLEAGUES IN THE PROGRAM AND 3813 02:12:03,000 --> 02:12:03,880 THIS RESEARCH, THEY JOINED OUR 3814 02:12:03,880 --> 02:12:05,760 LAB ESSENTIALLY AS EQUAL 3815 02:12:05,760 --> 02:12:06,840 CO-PARTNERS IN THE LAB, 3816 02:12:06,840 --> 02:12:08,360 CONTRIBUTING TO PAPERS, THINGS 3817 02:12:08,360 --> 02:12:08,800 LIKE THAT. 3818 02:12:08,800 --> 02:12:10,720 SO ONCE WE HAD THE BACKGROUND 3819 02:12:10,720 --> 02:12:12,880 AND THIS THEORY, WHAT WE WANTED 3820 02:12:12,880 --> 02:12:15,280 TO DO, WE DECIDED TO GO FOR IT 3821 02:12:15,280 --> 02:12:16,920 AND DO A GROUP FOR LAW 3822 02:12:16,920 --> 02:12:17,560 ENFORCEMENT OFFICERS. 3823 02:12:17,560 --> 02:12:19,760 WE GOT A SMALL PILOT GRANT. 3824 02:12:19,760 --> 02:12:22,680 THERE'S ONE OF MY 3825 02:12:22,680 --> 02:12:24,360 CO-FACILITATORS LEADING FOLKS 3826 02:12:24,360 --> 02:12:28,840 THROUGH AN EXERCISE. 3827 02:12:28,840 --> 02:12:31,240 WE HAD SOME PRETTY GOOD DATA, WE 3828 02:12:31,240 --> 02:12:32,880 FOUND SOME SIGNAL CHANGE ON 3829 02:12:32,880 --> 02:12:35,760 THINGS LIKE STRESS, RESILIENCE, 3830 02:12:35,760 --> 02:12:36,480 BURNOUT, THINGS LIKE THAT. 3831 02:12:36,480 --> 02:12:38,560 THROUGH SOME FOCUS GROUPS AND 3832 02:12:38,560 --> 02:12:39,680 THEN LEARNING AS WE WERE GOING, 3833 02:12:39,680 --> 02:12:44,480 WE LEARNED THAT MB -- IT NEEDED 3834 02:12:44,480 --> 02:12:46,680 CHANGES, IT NEEDED ADAPTATION. 3835 02:12:46,680 --> 02:12:47,960 A SIMPLE EXAMPLE IS A LOT OF 3836 02:12:47,960 --> 02:12:48,800 OFFICERS WERE RELUCK AT THAT 3837 02:12:48,800 --> 02:12:50,400 PARTICULAR TIME TO DO THE 3838 02:12:50,400 --> 02:12:51,520 TRADITIONAL BODY SCAN OF LYING 3839 02:12:51,520 --> 02:12:52,040 DOWN ON THE BACK. 3840 02:12:52,040 --> 02:12:54,160 SORT OF TALKING WITH THEM ABOUT 3841 02:12:54,160 --> 02:12:54,880 THAT, WHAT'S THE PROBLEM THAT 3842 02:12:54,880 --> 02:12:56,000 WAS GOING ON, IT WAS THAT YOU 3843 02:12:56,000 --> 02:12:59,040 HAD A ROOM FULL OF POLICE 3844 02:12:59,040 --> 02:13:00,680 OFFICERS, LYING DOWN ON THEIR 3845 02:13:00,680 --> 02:13:01,560 BACK WITHOUT THEIR WEAPONS AND 3846 02:13:01,560 --> 02:13:03,440 THEY FELT VERY VULNERABLE. 3847 02:13:03,440 --> 02:13:05,000 AT ANY POINT SOMEONE COULD COME 3848 02:13:05,000 --> 02:13:09,480 IN WITH A GUN, FOR EXAMPLE, SO 3849 02:13:09,480 --> 02:13:10,680 WE HAD THIS AGREEMENT THAT THE 3850 02:13:10,680 --> 02:13:12,080 DOOR STAYS LOCKED. 3851 02:13:12,080 --> 02:13:13,680 SO THE DOOR WAS LOCKED SO NO ONE 3852 02:13:13,680 --> 02:13:14,720 ELSE COULD COME IN THAT WASN'T 3853 02:13:14,720 --> 02:13:15,480 SUPPOSED TO BE THERE. 3854 02:13:15,480 --> 02:13:18,480 SO LITTLE THINGS LIKE THAT, ONE 3855 02:13:18,480 --> 02:13:19,720 OF THE THINGS WE REALLY FOCUSED 3856 02:13:19,720 --> 02:13:20,960 ON IN DISCUSSING THIS AND GOING 3857 02:13:20,960 --> 02:13:22,720 BACK TO THE LITERATURE WAS 3858 02:13:22,720 --> 02:13:23,720 RESILIENCE ENHANCEMENT. 3859 02:13:23,720 --> 02:13:24,880 THIS IS SOMETHING THAT THE 3860 02:13:24,880 --> 02:13:25,760 LITERATURE WAS TAKING OFF AT 3861 02:13:25,760 --> 02:13:28,400 THIS TIME AND WE FELT THAT WAS 3862 02:13:28,400 --> 02:13:30,000 SUCH AN IMPORTANT SKILLSET FOR 3863 02:13:30,000 --> 02:13:33,840 LAW ENFORCEMENT, IS IT'S 3864 02:13:33,840 --> 02:13:35,040 INEVITABLY A STRESSFUL JOB, 3865 02:13:35,040 --> 02:13:37,680 THERE ARE GOING TO BE TRAUMAS, 3866 02:13:37,680 --> 02:13:39,640 AND WE THOUGHT IS THERE A WAY WE 3867 02:13:39,640 --> 02:13:43,200 CAN CULTIVATE USING MINDFULNESS 3868 02:13:43,200 --> 02:13:44,720 FOR LAW ENFORCEMENT. 3869 02:13:44,720 --> 02:13:47,320 SO WE DEVELOPED MINDFULNESS 3870 02:13:47,320 --> 02:13:48,680 BASED RESILIENCE TRAINING. 3871 02:13:48,680 --> 02:13:52,680 SO WE GOT SOME FUNDING FROM 3872 02:13:52,680 --> 02:13:56,360 NCCIH FOR AT THE TIME WAS -- IT 3873 02:13:56,360 --> 02:13:58,080 WAS MORE OF A HIGH RISK HIGH 3874 02:13:58,080 --> 02:13:59,080 REWARD AS YOU ALL KNOW BUT WE 3875 02:13:59,080 --> 02:14:00,960 SORT OF SHAPED THIS WORK TO A 3876 02:14:00,960 --> 02:14:03,360 FEASIBILITY TRIAL. 3877 02:14:03,360 --> 02:14:07,720 SO FOR STARTERS, THIS WAS A 3878 02:14:07,720 --> 02:14:11,440 SINGLE -- A RELATIVELY SMALL 3879 02:14:11,440 --> 02:14:12,840 TRIAL HERE IN PORTLAND, OREGON. 3880 02:14:12,840 --> 02:14:14,720 AND WE ALSO WERE JUST LOOKING 3881 02:14:14,720 --> 02:14:17,320 AGAIN FOR SOME PRELIMINARY 3882 02:14:17,320 --> 02:14:17,680 SINGLE CHANGE. 3883 02:14:17,680 --> 02:14:23,840 IT WAS A SINGLE ARM -- AN RCT SO 3884 02:14:23,840 --> 02:14:26,000 WE WERE LOOKING AT STRESSOR 3885 02:14:26,000 --> 02:14:28,200 ACTIVITY, WANTED TO LOOK AT 3886 02:14:28,200 --> 02:14:31,840 BIOMARKER, WE LOOKED AT CORTISOL 3887 02:14:31,840 --> 02:14:32,720 AWAKENING RESPONSE. 3888 02:14:32,720 --> 02:14:34,920 WAS REAL INTERESTED TO SEE, 3889 02:14:34,920 --> 02:14:39,720 COULD WE MAKE A CHANGE IN 3890 02:14:39,720 --> 02:14:42,040 IMPLICIT RACE BIAS ACTIVATION BY 3891 02:14:42,040 --> 02:14:45,960 TRAINING IN MINDFULNESS, AND 3892 02:14:45,960 --> 02:14:46,920 LASTLY PSYCHOLOGICAL HEALTH AND 3893 02:14:46,920 --> 02:14:47,240 RISK. 3894 02:14:47,240 --> 02:14:48,680 SO IN TERMS OF OUR FEASIBILITY 3895 02:14:48,680 --> 02:14:51,520 MARKER, WE SET SOME BENCHMARKS. 3896 02:14:51,520 --> 02:14:52,880 SO JUST COULD WE RECRUIT, COULD 3897 02:14:52,880 --> 02:14:55,040 WE GET 60 OFFICERS IN THE 3898 02:14:55,040 --> 02:14:55,920 PORTLAND METRO AREA WILLING TO 3899 02:14:55,920 --> 02:14:58,640 DO THIS, WITH 90% OF THEM ACCEPT 3900 02:14:58,640 --> 02:15:02,720 BEING EITHER RANDOMIZED MBRP OR 3901 02:15:02,720 --> 02:15:03,520 THE RANDOMIZED CONTROL GROUP. 3902 02:15:03,520 --> 02:15:04,600 WOULD ABOUT THREE QUARTERS 3903 02:15:04,600 --> 02:15:05,680 ATTEND THE CLASSES AND MAKE ALL 3904 02:15:05,680 --> 02:15:08,880 THE CLASSES, AND COULD WE DO 3905 02:15:08,880 --> 02:15:10,280 THIS WITH 20% ATTRITION. 3906 02:15:10,280 --> 02:15:13,680 AND LUCKILY WE MET ALL THOSE 3907 02:15:13,680 --> 02:15:14,000 BENCHMARKS. 3908 02:15:14,000 --> 02:15:15,320 SO WE HAD THE PARTICIPANTS, 3909 02:15:15,320 --> 02:15:18,720 PEOPLE STUCK AROUND AND THEY 3910 02:15:18,720 --> 02:15:20,560 ACCEPTED THE RANDOMIZATION. 3911 02:15:20,560 --> 02:15:22,200 SIMILARLY FOR OUR ACCEPTABILITY 3912 02:15:22,200 --> 02:15:25,280 GOAL, WE JUST USED A FAIRLY 3913 02:15:25,280 --> 02:15:26,160 STRAIGHTFORWARD THREE-ITEM 3914 02:15:26,160 --> 02:15:27,760 MEASURE OF ACCEPTABILITY. 3915 02:15:27,760 --> 02:15:29,640 WE WERE JUST LOOKING FOR 3916 02:15:29,640 --> 02:15:33,000 RESPONSES IN A LIKELY OR 3917 02:15:33,000 --> 02:15:33,400 REASONABLE RANGE. 3918 02:15:33,400 --> 02:15:36,120 AND WHAT WE FOUND AGAIN, PRETTY 3919 02:15:36,120 --> 02:15:37,520 SIMILARLY, IS THAT MOST OFFICERS 3920 02:15:37,520 --> 02:15:38,320 WOULD RECOMMEND THIS TO A 3921 02:15:38,320 --> 02:15:38,600 FRIEND. 3922 02:15:38,600 --> 02:15:40,720 THEY'D DO IT AGAIN IF IT WERE 3923 02:15:40,720 --> 02:15:42,240 OFFERED AGAIN BUT THEY DID FIND 3924 02:15:42,240 --> 02:15:44,000 THE WHOLE PRACTICE A LITTLE 3925 02:15:44,000 --> 02:15:44,640 UNREASONABLE. 3926 02:15:44,640 --> 02:15:46,600 THAT WAS AGAIN PART OF OUR 3927 02:15:46,600 --> 02:15:47,480 ADAPTATION PROCESS. 3928 02:15:47,480 --> 02:15:49,880 MAYBE 45 MINUTE A DAY OF 3929 02:15:49,880 --> 02:15:51,520 MEDITATION HOMEWORK JUST MIGHT 3930 02:15:51,520 --> 02:15:52,440 NOT BE FEASIBLE FOR THIS 3931 02:15:52,440 --> 02:15:53,200 POPULATION. 3932 02:15:53,200 --> 02:15:55,480 IN TERMS OF OUR OUTCOMES, AGAIN 3933 02:15:55,480 --> 02:15:56,680 WE WERE REALLY MORE INTERESTED 3934 02:15:56,680 --> 02:15:58,240 IN JUST LOOKING AT WERE THEY 3935 02:15:58,240 --> 02:15:59,200 FEASIBLE. 3936 02:15:59,200 --> 02:16:01,720 SO WE FOUND WITH CORTISOL 3937 02:16:01,720 --> 02:16:03,120 AWAKENING RESPONSES, AGAIN, WE 3938 02:16:03,120 --> 02:16:05,320 HAD OFFICERS DOING THIS THREE 3939 02:16:05,320 --> 02:16:07,720 DAYS PREINTERVENTION AND THREE 3940 02:16:07,720 --> 02:16:09,280 DAYS POST, SO THOSE WHO HAVE 3941 02:16:09,280 --> 02:16:11,000 ACTUALLY DONE THIS, IT'S QUITE A 3942 02:16:11,000 --> 02:16:12,120 CHALLENGE FIRST THING IN THE 3943 02:16:12,120 --> 02:16:14,280 MORNING TO COLLECT SALIVA THREE 3944 02:16:14,280 --> 02:16:15,280 TIMES, DO NOT EAT, DRINK, DO 3945 02:16:15,280 --> 02:16:19,640 ANYTHING ELSE, SO WE WE ARE WERY 3946 02:16:19,640 --> 02:16:20,640 PLEASANTLY SUR PLIED WE HAD 3947 02:16:20,640 --> 02:16:23,920 ABOUT A 95% COMPLETION RATE. 3948 02:16:23,920 --> 02:16:26,560 THIS IS CALLED THE SHOOTER BIAS 3949 02:16:26,560 --> 02:16:26,760 TASK. 3950 02:16:26,760 --> 02:16:29,200 WHAT IT DOES VERY BRIEFLY IS 3951 02:16:29,200 --> 02:16:31,480 LOOK AT IMPLICIT BIAS IN 3952 02:16:31,480 --> 02:16:33,040 DECISION SHOOT OR NO SHOOT. 3953 02:16:33,040 --> 02:16:34,920 WE WERE CONCERNED THAT POLICE 3954 02:16:34,920 --> 02:16:36,200 OFFICERS WOULD REFUSE AT HIGH 3955 02:16:36,200 --> 02:16:36,960 NUMBERS TO DO THIS BECAUSE, 3956 02:16:36,960 --> 02:16:38,080 AGAIN, WE WERE COLLECTING THIS 3957 02:16:38,080 --> 02:16:39,560 DATA AND ALTHOUGH, AGAIN, 3958 02:16:39,560 --> 02:16:41,360 OBVIOUSLY IT WAS CONFIDENTIAL 3959 02:16:41,360 --> 02:16:44,600 AND NOMINALIZED, AFTER WE HAD A 3960 02:16:44,600 --> 02:16:46,000 CERTIFICATE OF CONFIDENTIALITY, 3961 02:16:46,000 --> 02:16:47,240 WE THOUGHT WE WOULD HAVE SOME 3962 02:16:47,240 --> 02:16:48,680 OFFICERS WHO WOULD FLAT OUT 3963 02:16:48,680 --> 02:16:49,320 REFUSE DO THIS. 3964 02:16:49,320 --> 02:16:51,000 SO AGAIN YOU'RE PROVIDED WITH 3965 02:16:51,000 --> 02:16:52,160 IMAGES OF EITHER A WHITE OR 3966 02:16:52,160 --> 02:16:53,280 BLACK MALE HOLDING SOMETHING 3967 02:16:53,280 --> 02:16:54,640 LIKE EITHER A CELL PHONE OR A 3968 02:16:54,640 --> 02:16:56,280 GUN, AND YOU HAVE TO MAKE THAT 3969 02:16:56,280 --> 02:16:57,840 QUICK WITHIN A FEW MILLISECONDS 3970 02:16:57,840 --> 02:16:58,920 DECISION OF WHETHER TO SAY THAT 3971 02:16:58,920 --> 02:17:01,040 THEY'RE HOLDING A WEAPON OR 3972 02:17:01,040 --> 02:17:02,080 THEY'RE HOLDING SOMETHING LIKE A 3973 02:17:02,080 --> 02:17:02,520 CELL PHONE. 3974 02:17:02,520 --> 02:17:04,600 SO WE HAD 100% COMPLIANCE HERE, 3975 02:17:04,600 --> 02:17:06,160 WE DIDN'T HAVE A SINGLE OFFICER 3976 02:17:06,160 --> 02:17:06,920 REFUSE TO DO IT. 3977 02:17:06,920 --> 02:17:08,800 AND THEN OUR LAST TWO SORT OF 3978 02:17:08,800 --> 02:17:10,440 OUTCOMES, AGAIN, WE HAD SOME 3979 02:17:10,440 --> 02:17:12,320 SELF-REPORT MEASURES, 100% 3980 02:17:12,320 --> 02:17:18,080 COMPLETION RATE, AND WE'VE 3981 02:17:18,080 --> 02:17:20,720 BEEN -- WE OBVIOUSLY WERE 3982 02:17:20,720 --> 02:17:21,600 PLEASANTLY SURPRISE HEERD AS 3983 02:17:21,600 --> 02:17:24,080 WELL, ABOUT 322 MINUTES OF HOME 3984 02:17:24,080 --> 02:17:25,000 PRACTICE. 3985 02:17:25,000 --> 02:17:26,560 IT WASN'T EXACTLY THAT 45 3986 02:17:26,560 --> 02:17:27,720 MINUTES A DAY THAT WE HAD HOPED 3987 02:17:27,720 --> 02:17:29,040 BUT WE LEARNED PRETTY QUICKLY 3988 02:17:29,040 --> 02:17:30,560 THAT'S JUST NOT REALISTIC, AS 3989 02:17:30,560 --> 02:17:33,080 IT'S NOT IN MOST SAMPLES. 3990 02:17:33,080 --> 02:17:34,480 SO FELT PRETTY GOOD ABOUT THAT. 3991 02:17:34,480 --> 02:17:36,480 I JUST WANT TO READ A COUPLE 3992 02:17:36,480 --> 02:17:36,800 QUOTES HERE. 3993 02:17:36,800 --> 02:17:40,440 I KNOW I'M SORT OF RUNNING SHORT 3994 02:17:40,440 --> 02:17:42,720 ON TIME BUT WE ALSO DID SOME 3995 02:17:42,720 --> 02:17:44,320 INTERVIEWS AND GOT SOME REALLY 3996 02:17:44,320 --> 02:17:45,440 NICE QUOTES FROM OFFICERS. 3997 02:17:45,440 --> 02:17:46,960 I USED TO FLY OFF THE HANDLE, I 3998 02:17:46,960 --> 02:17:48,520 DON'T SO MUCH ANYMORE, WHICH IS 3999 02:17:48,520 --> 02:17:49,600 REALLY NICE. 4000 02:17:49,600 --> 02:17:51,680 RM "PUN TIME MY WIFE TOLD ME, I 4001 02:17:51,680 --> 02:17:52,880 CAN ACTUALLY SEE THE CLASS KICK 4002 02:17:52,880 --> 02:17:54,080 IN WHILE WE WERE TALKING. 4003 02:17:54,080 --> 02:17:59,560 AND SHE'S JUST LIKE -- HELPED ME 4004 02:17:59,560 --> 02:18:00,080 NOT ESCALATE. 4005 02:18:00,080 --> 02:18:01,440 SO IT WAS REALLY NICE AGAIN TO 4006 02:18:01,440 --> 02:18:02,840 HEAR FROM THE OFFICERS, SORT OF 4007 02:18:02,840 --> 02:18:04,160 THEIR LIVED EXPERIENCE WITH THIS 4008 02:18:04,160 --> 02:18:08,520 COURSE. 4009 02:18:08,520 --> 02:18:09,720 SO LESSONS LEARNED SORT OF 4010 02:18:09,720 --> 02:18:11,280 QUICKLY IS, AS WITH ANY 4011 02:18:11,280 --> 02:18:12,160 COLLABORATIVE RESEARCH PROJECT, 4012 02:18:12,160 --> 02:18:14,120 IT WAS REALLY IMPORTANT FOR US 4013 02:18:14,120 --> 02:18:15,440 TO ENGAGE POLICE LEADERSHIP 4014 02:18:15,440 --> 02:18:20,240 EARLY ON THROUGHOUT THE PROJECT. 4015 02:18:20,240 --> 02:18:21,920 ALTHOUGH WE HAD A LOW DROPOUT 4016 02:18:21,920 --> 02:18:23,640 RATE T OCCURRED MOSTLY AFTER 4017 02:18:23,640 --> 02:18:24,160 THAT FIRST GROUP. 4018 02:18:24,160 --> 02:18:25,680 SO WE LOST THREE OR FOUR 4019 02:18:25,680 --> 02:18:27,160 PARTICIPANTS AFTER JUST OUR 4020 02:18:27,160 --> 02:18:28,640 NORMAL TWO-HOUR SESSIONS, SO WE 4021 02:18:28,640 --> 02:18:29,760 THOUGHT MAYBE WE NEED TO DO 4022 02:18:29,760 --> 02:18:31,520 SOMETHING TO GET BETTER BUY-IN 4023 02:18:31,520 --> 02:18:32,400 AT THE BEGINNING. 4024 02:18:32,400 --> 02:18:33,680 THE POLICE OFFICER DILEMMA, 4025 02:18:33,680 --> 02:18:35,440 WHICH WE SHOWED YOU, ALTHOUGH WE 4026 02:18:35,440 --> 02:18:37,880 HAD 100% OF OFFICERS DO IT, THEY 4027 02:18:37,880 --> 02:18:39,720 DID REALLY WELL ON IT, ALMOST 4028 02:18:39,720 --> 02:18:40,160 TOO WELL. 4029 02:18:40,160 --> 02:18:43,280 AND WE KNEELED -- REALLY NEEDED 4030 02:18:43,280 --> 02:18:46,960 A MORE SOPHISTICATED DESIGN FOR 4031 02:18:46,960 --> 02:18:48,640 A PAPILLATION THAT'S VERY WELL 4032 02:18:48,640 --> 02:18:59,640 TRAINED IN POPULATION THAD 4033 02:18:59,920 --> 02:19:01,200 AT -- -- THAT WAS REALLY 4034 02:19:01,200 --> 02:19:05,120 DISHEARTEN, WE NEEDED TO DO MORE 4035 02:19:05,120 --> 02:19:07,320 TO KEEP THEM -- ALTHOUGH IT IS 4036 02:19:07,320 --> 02:19:10,200 PRIMARILY A MALE PROFESSION, WE 4037 02:19:10,200 --> 02:19:14,880 HAD 90% MALE AND 80% WHITE 4038 02:19:14,880 --> 02:19:16,000 SAMPLE SO WE WANT TO DO BETTER 4039 02:19:16,000 --> 02:19:17,520 IN OUR NEXT ROUND. 4040 02:19:17,520 --> 02:19:20,360 SO BASED OFF OF THE R21, WE 4041 02:19:20,360 --> 02:19:23,200 APPLIED AND RECEIVED A U01 FOR A 4042 02:19:23,200 --> 02:19:24,960 MULTISITE FEASIBILITY TRIAL. 4043 02:19:24,960 --> 02:19:26,280 SO HERE WE WERE TAKING WHAT WE 4044 02:19:26,280 --> 02:19:28,160 LEARNED FROM THIS TRIAL AND NOW 4045 02:19:28,160 --> 02:19:30,120 WE WERE EXPANDING THAT OUT TO 4046 02:19:30,120 --> 02:19:35,280 DISTANT SITES, SO HERE AGAIN IN 4047 02:19:35,280 --> 02:19:43,040 PORTLAND, COLLEAGUES, AGAIN THE 4048 02:19:43,040 --> 02:19:44,800 GOAL HERE WAS A MULTISITE 4049 02:19:44,800 --> 02:19:45,840 FEASIBILITY TRIAL. 4050 02:19:45,840 --> 02:19:47,720 CAN WE REPLICATE WHAT WE'VE DONE 4051 02:19:47,720 --> 02:19:48,840 AND CAN WE DO THAT IN 4052 02:19:48,840 --> 02:19:50,480 PREPARATION FOR A FULL SCALE 4053 02:19:50,480 --> 02:19:51,800 EFFICACY TRIAL. 4054 02:19:51,800 --> 02:19:55,640 SO NEXT STEPS JUST REAL QUICKLY 4055 02:19:55,640 --> 02:19:57,120 HERE, SOME OF YOU MIGHT 4056 02:19:57,120 --> 02:19:58,120 RECOGNIZE THESE FACES. 4057 02:19:58,120 --> 02:19:59,960 WE RECRUITED SARAH TO COME JOIN 4058 02:19:59,960 --> 02:20:01,640 US AT PACIFIC A FEW YEARS AGO. 4059 02:20:01,640 --> 02:20:04,240 HER BACKGROUND IS REALLY MORE IN 4060 02:20:04,240 --> 02:20:05,280 MBRP AND ADICKS. 4061 02:20:05,280 --> 02:20:09,680 BUT AFTER A LOT OF A CAJOLING D 4062 02:20:09,680 --> 02:20:11,320 PUSHING WE GOT HER EXCITE TODAY 4063 02:20:11,320 --> 02:20:12,400 JOIN ME ON THIS PROJECT. 4064 02:20:12,400 --> 02:20:13,720 MANY OF YOU PROBABLY KNOW, THESE 4065 02:20:13,720 --> 02:20:15,240 TWO ARE REALLY SORT OF THE CORE 4066 02:20:15,240 --> 02:20:18,440 DEVELOPERS ALONG WITH ALLAN, OF 4067 02:20:18,440 --> 02:20:19,720 COURSE, OF -- PREVENTION. 4068 02:20:19,720 --> 02:20:21,160 AND THEIR INFLUENCE WAS SORT OF 4069 02:20:21,160 --> 02:20:24,200 WHERE WE WENT THE NEXT DIRECTION 4070 02:20:24,200 --> 02:20:26,200 OF MBRT WAS REALLY IMPORTANT. 4071 02:20:26,200 --> 02:20:28,160 WE SORT OF SHIFTED AWAY A LITTLE 4072 02:20:28,160 --> 02:20:32,680 BIT FROM MBSR ALTHOUGH IT WAS A 4073 02:20:32,680 --> 02:20:34,400 QUICK COUSIN -- ONE OF THE 4074 02:20:34,400 --> 02:20:35,760 IMPORTANT DISTINCTIONS WE'VE 4075 02:20:35,760 --> 02:20:37,240 MADE HERE IS THAT REACTIVITY IS 4076 02:20:37,240 --> 02:20:38,560 REALLY ONE OF THE CORE TARGETS 4077 02:20:38,560 --> 02:20:41,520 WITHIN MBRP, SORT OF LOOKING AT 4078 02:20:41,520 --> 02:20:42,840 AGAIN PREDICTIONS BUT IT REALLY 4079 02:20:42,840 --> 02:20:44,920 FIT WITH WHAT WE WERE KIND OF 4080 02:20:44,920 --> 02:20:45,920 THINKING WAS OUR PRIMARY 4081 02:20:45,920 --> 02:20:46,960 MECHANISM, BOTH FROM THE 4082 02:20:46,960 --> 02:20:49,200 PRELIMINARY DATA WE HAD BUT JUST 4083 02:20:49,200 --> 02:20:50,280 ANECDOTALLY SO SOME OF THE 4084 02:20:50,280 --> 02:20:51,920 QUOTES THAT WE CAPTURED EARLIER, 4085 02:20:51,920 --> 02:20:53,120 DECREASING THAT REACTIVITY 4086 02:20:53,120 --> 02:20:56,440 DURING TIMES OF STRESS LEADING 4087 02:20:56,440 --> 02:21:01,800 TO BAD OUTCOMES ESSENTIALLY IN 4088 02:21:01,800 --> 02:21:02,080 POLICING. 4089 02:21:02,080 --> 02:21:02,920 OBVIOUSLY A HIGH TRAUMA 4090 02:21:02,920 --> 02:21:04,080 POPULATION, SO WE INTEGRATED 4091 02:21:04,080 --> 02:21:05,880 THAT MORE INTO THIS NEXT PHASE 4092 02:21:05,880 --> 02:21:06,840 OF MBRT. 4093 02:21:06,840 --> 02:21:08,360 WE ALSO BASED ON THE PILOT WORK 4094 02:21:08,360 --> 02:21:10,360 WE HAD DONE REALIZED THAT -- 4095 02:21:10,360 --> 02:21:12,520 WERE GETTING LOTS OF MOVEMENT, 4096 02:21:12,520 --> 02:21:13,880 LOTS OF SIGNAL CHANGE, LOTS OF 4097 02:21:13,880 --> 02:21:18,120 BODY WORK WITH THE OFFICERS 4098 02:21:18,120 --> 02:21:21,640 RESPONDED WELL TO. 4099 02:21:21,640 --> 02:21:23,600 SO WE DECIDED TO MOVE TO A 4100 02:21:23,600 --> 02:21:25,440 SIX-HOUR IMMERSION IN WEEK ONE 4101 02:21:25,440 --> 02:21:27,440 TO GET MORE BUY-IN, AND THEN ON 4102 02:21:27,440 --> 02:21:29,920 THE END, ADD BOOSTER SESSIONS TO 4103 02:21:29,920 --> 02:21:31,560 HOPEFULLY FOSTER MORE PRACTICE. 4104 02:21:31,560 --> 02:21:34,400 AND THEN LASTLY, WE SHIFTED MORE 4105 02:21:34,400 --> 02:21:36,360 TO AN ACUTE STRESS CHALLENGE. 4106 02:21:36,360 --> 02:21:38,920 WE WANTED TO SEE HOW OFFICERS 4107 02:21:38,920 --> 02:21:40,320 RESPONDED TO A STRESS PATH IN 4108 02:21:40,320 --> 02:21:43,800 THE LAB, MEASURING THESE 4109 02:21:43,800 --> 02:21:44,960 PARAMETERS AND LOOKING AT THAT 4110 02:21:44,960 --> 02:21:46,680 AGAIN AFTER AND SEEING IF WE 4111 02:21:46,680 --> 02:21:47,880 WOULD HAVE NOT AT HIGH AS A PEAK 4112 02:21:47,880 --> 02:21:49,400 BUT ALSO A QUICKER RETURN BACK 4113 02:21:49,400 --> 02:21:50,080 TO BASELINE. 4114 02:21:50,080 --> 02:21:52,240 AND THIS NEXT STEP TOO, WE 4115 02:21:52,240 --> 02:21:54,440 INCLUDED AN ACTIVE CONTROL 4116 02:21:54,440 --> 02:21:58,720 CONDITION, STRESS MANAGEMENT 4117 02:21:58,720 --> 02:21:59,160 EDUCATION. 4118 02:21:59,160 --> 02:22:00,760 AND LASTLY, BECAUSE IT WAS MORE 4119 02:22:00,760 --> 02:22:02,000 OF A FEASIBILITY TRIAL, WE 4120 02:22:02,000 --> 02:22:06,400 REALLY WANTED TO MOVE FROM -- IT 4121 02:22:06,400 --> 02:22:07,600 WAS STILL INCLUDING SORT OF 4122 02:22:07,600 --> 02:22:09,000 SELF-REPORT AND OTHER MEASURES 4123 02:22:09,000 --> 02:22:10,000 OF AGGRESSION AND USE OF FORCE 4124 02:22:10,000 --> 02:22:12,520 TO ACTUALLY COLLECTING 4125 02:22:12,520 --> 02:22:15,480 BEHAVIORAL DATA, ACTUALLY USE 4126 02:22:15,480 --> 02:22:16,440 SOME FORCE. 4127 02:22:16,440 --> 02:22:18,400 TO SEE IF A IT WAS FEASIBLE TO 4128 02:22:18,400 --> 02:22:20,640 COLLECT AND B IF WE COULD DETECT 4129 02:22:20,640 --> 02:22:21,600 ANY SLOT CHANGES. 4130 02:22:21,600 --> 02:22:23,800 MOVING TO MORE OF THAT ACUTE 4131 02:22:23,800 --> 02:22:26,880 PHYSIOLOGICAL ACTIVITY. 4132 02:22:26,880 --> 02:22:29,080 SO WE PARTNERED WITH OUR THREE 4133 02:22:29,080 --> 02:22:34,080 AGENCIES IN THE THREE CITIES, 4134 02:22:34,080 --> 02:22:36,080 AND OUR STUDY STARTED WITH AN 4135 02:22:36,080 --> 02:22:38,040 ENTIRELY IN-PERSON PROTOCOL. 4136 02:22:38,040 --> 02:22:39,360 OFFICERS WERE COMING TO THE LAB, 4137 02:22:39,360 --> 02:22:44,160 WE WERE STRESSING THEM OUT, AND 4138 02:22:44,160 --> 02:22:45,080 GROUPS ENTEARLY IN PERSON. 4139 02:22:45,080 --> 02:22:50,240 WE STARTED OFF IN ALBUQUERQUE, 4140 02:22:50,240 --> 02:22:51,360 FIRST PARTICIPANT JANUARY 5TH, 4141 02:22:51,360 --> 02:22:55,200 2020, WE HAD 24 AND WE COMPLETED 4142 02:22:55,200 --> 02:22:56,800 OUR FIRST GROUP, WE WERE SO 4143 02:22:56,800 --> 02:22:58,880 EXCITED, ON MARCH 11, 2020. 4144 02:22:58,880 --> 02:23:01,000 AND THE NEXT DAY, COVID 4145 02:23:01,000 --> 02:23:02,960 ESSENTIALLY HIT AND SHUT US 4146 02:23:02,960 --> 02:23:06,040 DOWN. 4147 02:23:06,040 --> 02:23:07,880 SO IT WAS 3/12, OUR SITES WENT 4148 02:23:07,880 --> 02:23:08,520 INTO LOCKDOWN. 4149 02:23:08,520 --> 02:23:10,160 WE WERE SORT OF IN A HOLDING 4150 02:23:10,160 --> 02:23:11,680 PATTERN, NOT SURE WHAT TO DO FOR 4151 02:23:11,680 --> 02:23:13,960 A WHILE AND AS YOU ALL KNOW, TWO 4152 02:23:13,960 --> 02:23:15,520 MONTHS AFTER THAT, GEORGE FLOYD 4153 02:23:15,520 --> 02:23:17,200 WAS MURDERED IN MINNEAPOLIS, AND 4154 02:23:17,200 --> 02:23:20,720 IT WAS REALLY A TOUGH TIME 4155 02:23:20,720 --> 02:23:21,360 FRANKLY. 4156 02:23:21,360 --> 02:23:22,760 BETWEEN COVID AND NOT SURE WHAT 4157 02:23:22,760 --> 02:23:24,000 TO DO, BUT GEORGE FLOYD'S MURDER 4158 02:23:24,000 --> 02:23:26,360 AND THEN THE SOCIAL PROTESTS FOR 4159 02:23:26,360 --> 02:23:28,800 SOCIAL JUSTICE AFTER THAT, AS A 4160 02:23:28,800 --> 02:23:32,640 TEAM, WE REALLY SPENT A LOT OF 4161 02:23:32,640 --> 02:23:34,200 TIME TO SORT OF FIGURE OUT THIS 4162 02:23:34,200 --> 02:23:35,920 WAS THE RESEARCH WE WANTED TO 4163 02:23:35,920 --> 02:23:37,240 KEEP DOING, DO YOU WANT TO 4164 02:23:37,240 --> 02:23:38,360 SHIFT, DO YOU WANT TO DO 4165 02:23:38,360 --> 02:23:38,880 SOMETHING DIFFERENT. 4166 02:23:38,880 --> 02:23:40,960 SO WE TOOK A SIX MONTH PAUSE AND 4167 02:23:40,960 --> 02:23:44,240 I WANT TO MENTION HOW HELPFUL -- 4168 02:23:44,240 --> 02:23:45,880 WAS DURING THIS TIME, KEEPING US 4169 02:23:45,880 --> 02:23:48,080 ON TRACK, COMING BACK TOGETHER, 4170 02:23:48,080 --> 02:23:49,400 AND AT THE END, CONSULTING WITH 4171 02:23:49,400 --> 02:23:51,360 COMMUNITY MEMBERS AND OTHER 4172 02:23:51,360 --> 02:23:53,120 PEOPLE, OKAY, WE REALLY NEED TO 4173 02:23:53,120 --> 02:23:55,840 GET BACK TO WORK HERE, TO MOVE 4174 02:23:55,840 --> 02:23:56,400 FORWARD WITH THIS. 4175 02:23:56,400 --> 02:23:58,640 SO WE SHIFTED GEARS, TAKE TWO 4176 02:23:58,640 --> 02:23:59,920 HERE, AND SWITCHED FROM ENTIRELY 4177 02:23:59,920 --> 02:24:03,600 IN PERSON TO AN ENTIRELY 4178 02:24:03,600 --> 02:24:05,280 VIRTUALLY PROTOCOL, WHICH AS YOU 4179 02:24:05,280 --> 02:24:08,880 CAN IMAGINE WAS QUITE AN 4180 02:24:08,880 --> 02:24:09,240 UNDERTAKING. 4181 02:24:09,240 --> 02:24:11,080 WE WERE THEN SHIFTED OVER TO 4182 02:24:11,080 --> 02:24:12,600 INFLAMMATORY MARKER, WHICH WAS 4183 02:24:12,600 --> 02:24:13,840 AGAIN MORE OF A CHRONIC MEASURE 4184 02:24:13,840 --> 02:24:15,920 BUT WE THOUGHT AT LEAST IT KEEPS 4185 02:24:15,920 --> 02:24:17,240 SOME BIOMARKERS WE COULD LOOK 4186 02:24:17,240 --> 02:24:18,800 FOR THAT CHANGE AND AGAIN, ALL 4187 02:24:18,800 --> 02:24:22,920 DATA THAT THAT WERE NOW COLL, 4188 02:24:22,920 --> 02:24:26,600 DELIVERED VIA ZOOM. 4189 02:24:26,600 --> 02:24:28,640 SO WE ENROLLED OUR FIRST 4190 02:24:28,640 --> 02:24:30,040 PARTICIPANT IN MID DECEMBER OF 4191 02:24:30,040 --> 02:24:32,560 2020. 4192 02:24:32,560 --> 02:24:38,040 AND THE -- AGAIN VIRTUALLY AND 4193 02:24:38,040 --> 02:24:40,240 STRESS -- AP DAP TAITION IN OUR 4194 02:24:40,240 --> 02:24:40,560 THREE SITES. 4195 02:24:40,560 --> 02:24:42,640 VERY RECENTLY WE JUST FINISHED 4196 02:24:42,640 --> 02:24:43,960 OR SIX MONTH FOLLOW-UP DATA 4197 02:24:43,960 --> 02:24:44,480 COLLECTION. 4198 02:24:44,480 --> 02:24:45,720 WE MANAGED TO DO IT ALL 4199 02:24:45,720 --> 02:24:46,160 VIRTUALLY. 4200 02:24:46,160 --> 02:24:47,680 THIS WAS ABOUT A COUPLE, TWO 4201 02:24:47,680 --> 02:24:49,200 MONTHS AGO THAT WE FINISHED DATA 4202 02:24:49,200 --> 02:24:49,560 COLLECTION. 4203 02:24:49,560 --> 02:24:50,760 SO I'LL JUST QUICKLY GO THROUGH 4204 02:24:50,760 --> 02:24:52,720 SORT OF OUR BENCHMARKS THAT WE 4205 02:24:52,720 --> 02:24:56,520 FOUND AND LUCKILY WE FOUND THAT 4206 02:24:56,520 --> 02:24:58,320 MULTISITE TRIAL, DESPITE SOME OF 4207 02:24:58,320 --> 02:24:59,320 THE ISSUES THAT WE DEALT WITH, 4208 02:24:59,320 --> 02:25:00,920 THAT WE HIT OUR ENROLLMENT 4209 02:25:00,920 --> 02:25:01,160 TARGETS. 4210 02:25:01,160 --> 02:25:02,480 WE WERE VERY HAPPY TO SEE THAT 4211 02:25:02,480 --> 02:25:04,200 WE REALLY MADE A STRONG EFFORT 4212 02:25:04,200 --> 02:25:06,520 TO RECRUIT A DIVERSE SAMPLE IN 4213 02:25:06,520 --> 02:25:09,720 ALL THREE OF OUR SITES, AND WE 4214 02:25:09,720 --> 02:25:11,720 ACTUALLY EXCEEDED OUR DIVERSITY 4215 02:25:11,720 --> 02:25:12,640 TARGETS. 4216 02:25:12,640 --> 02:25:20,080 WE HAD ALMOST WERE FEMALE. 4217 02:25:20,080 --> 02:25:21,280 LARGELY ACCEPTED RANDOMIZATION. 4218 02:25:21,280 --> 02:25:23,160 WE WERE REALLY HAPPY WITH OUR 4219 02:25:23,160 --> 02:25:25,000 RETENTION EFFORTS THAT, WE KEPT 4220 02:25:25,000 --> 02:25:27,240 86% OF OUR OFFICERS AT SIX 4221 02:25:27,240 --> 02:25:28,080 MONTHS OUT. 4222 02:25:28,080 --> 02:25:29,520 REALLY HIGH RATES OF COMPLETION 4223 02:25:29,520 --> 02:25:30,360 WITH DATA. 4224 02:25:30,360 --> 02:25:31,720 THOUGH ONE THAT WE DIDN'T MEET 4225 02:25:31,720 --> 02:25:33,120 WAS OUR DRY BLOODSPOTS. 4226 02:25:33,120 --> 02:25:34,840 SO WE WERE MAILING THEM OUT TO 4227 02:25:34,840 --> 02:25:36,600 PARTICIPANTS HAVING TO DO IT AT 4228 02:25:36,600 --> 02:25:37,920 HOME WHILE WE WERE WALKING 4229 02:25:37,920 --> 02:25:42,640 THROUGH IT ON ZOOM. 4230 02:25:42,640 --> 02:25:43,840 FEDEX UNFORTUNATELY LOST A BATCH 4231 02:25:43,840 --> 02:25:46,240 OF THEM SO I WON'T CLAIM FULL 4232 02:25:46,240 --> 02:25:50,440 RESPONSIBILITY UNFORTUNATELY FOR 4233 02:25:50,440 --> 02:25:53,040 NOT MEETING THIS BENCHMARK. 4234 02:25:53,040 --> 02:25:55,560 AND WE HAD OUR T GROUP, WHICH 4235 02:25:55,560 --> 02:25:57,360 WAS GREAT, THE VAST MAJORITY DID 4236 02:25:57,360 --> 02:26:02,560 ATTEND, R. AT LEAST FIVE E 4237 02:26:02,560 --> 02:26:02,920 SESSIONS. 4238 02:26:02,920 --> 02:26:04,960 AND THEN LASTLY, OUR 4239 02:26:04,960 --> 02:26:06,520 PARTICIPANTS FOUND IT 4240 02:26:06,520 --> 02:26:10,480 ACCEPTABLE. 4241 02:26:10,480 --> 02:26:12,760 AND THEN TO SUMMARIZE, THIS IS 4242 02:26:12,760 --> 02:26:14,080 REALLY THE PART WE'RE WORKING ON 4243 02:26:14,080 --> 02:26:14,400 AS WE SPEAK. 4244 02:26:14,400 --> 02:26:21,200 SO WIRE LOOKING WE'RE LOY 4245 02:26:21,200 --> 02:26:23,280 AGAIN, FIDELITY ACROSS SITES, SO 4246 02:26:23,280 --> 02:26:25,640 WE'RE LOOKING VERY CAREFULLY TO 4247 02:26:25,640 --> 02:26:29,480 SEE HOW WELL OUR 4248 02:26:29,480 --> 02:26:30,120 INTERVENTIONISTS -- IN EACH OF 4249 02:26:30,120 --> 02:26:30,680 THE THREE SITES. 4250 02:26:30,680 --> 02:26:32,120 AGAIN OUR ANALYSIS HERE, WE'RE 4251 02:26:32,120 --> 02:26:34,520 NOT LOOKING AT GROUP DIFFERENTS. 4252 02:26:34,520 --> 02:26:37,480 WE'RE REALLY LOOKING AT MORE 4253 02:26:37,480 --> 02:26:39,920 EFFICIENCY OF MEASURES AND 4254 02:26:39,920 --> 02:26:41,080 SENSITIVITY TO CHANGE. 4255 02:26:41,080 --> 02:26:47,640 BUT LUCKILY -- NON-REACTIVITY, 4256 02:26:47,640 --> 02:26:50,720 INTERNAL 4257 02:26:50,720 --> 02:26:52,360 INTERROW ACCEPTIVE AWARENESS ARE 4258 02:26:52,360 --> 02:26:53,680 EFFICIENT AND SENSITIVE TO 4259 02:26:53,680 --> 02:26:54,440 CHANGE. 4260 02:26:54,440 --> 02:26:55,640 EXCESSIVE USE OF FORCE DATA, 4261 02:26:55,640 --> 02:26:57,440 THIS IS CALLED BLUE TEAM, SO WE 4262 02:26:57,440 --> 02:27:01,040 HAVE REAMS OF DATA OF USE OF 4263 02:27:01,040 --> 02:27:01,400 FORCE. 4264 02:27:01,400 --> 02:27:05,960 WE WERE UNABLE TO GET THIS IN 4265 02:27:05,960 --> 02:27:09,280 ALBUQUERQUE, BUT AT LEAST WE 4266 02:27:09,280 --> 02:27:09,880 HAVE ONE THERE, THEAND WE'RE 4267 02:27:09,880 --> 02:27:12,240 WORKING ON OUR INFLAMMATION 4268 02:27:12,240 --> 02:27:15,280 BIOMARKER TATA NOW. 4269 02:27:15,280 --> 02:27:16,040 DATA NOW. 4270 02:27:16,040 --> 02:27:18,680 WE'VE GOT 47 INTERVIEW, SO LOTS 4271 02:27:18,680 --> 02:27:19,880 OF RICH THEMES COMING OUT OF 4272 02:27:19,880 --> 02:27:21,640 THIS ACROSS ALL PHASES OF THE 4273 02:27:21,640 --> 02:27:23,000 STUDY. 4274 02:27:23,000 --> 02:27:27,680 NOT JUST THE -- AND ALL THE 4275 02:27:27,680 --> 02:27:28,680 DIFFERENT ASPECTS. 4276 02:27:28,680 --> 02:27:32,640 LASTLY AGAIN, PRETTY -- WE DON'T 4277 02:27:32,640 --> 02:27:36,320 HAVE MINUTES -- AT LEAST 95% DID 4278 02:27:36,320 --> 02:27:36,480 IT. 4279 02:27:36,480 --> 02:27:38,440 SO VERY QUICKLY, SOME NEXT 4280 02:27:38,440 --> 02:27:39,920 STEPS, AGAIN WE'RE GOING TO 4281 02:27:39,920 --> 02:27:40,920 ANALYZE THIS DATA AND THEN OUR 4282 02:27:40,920 --> 02:27:42,560 FINAL STEP HOPEFULLY IF ALL GOES 4283 02:27:42,560 --> 02:27:44,000 WELL ONCE WE PUBLISH SOME OF THE 4284 02:27:44,000 --> 02:27:48,920 PAPERS FROM THIS IS TO SUBMIT 4285 02:27:48,920 --> 02:27:49,800 APPLICATIONS IN OCTOBER SO WE'VE 4286 02:27:49,800 --> 02:27:51,640 MET MOST OF OUR BENCHMARKS AND 4287 02:27:51,640 --> 02:27:54,080 WE'LL FIND OUT AGAIN HOW WE DO 4288 02:27:54,080 --> 02:27:55,720 ON THE OTHER MEASURES. 4289 02:27:55,720 --> 02:28:00,960 JUST LASTLY, WE'RE OPENING AGAIN 4290 02:28:00,960 --> 02:28:03,440 TO MOVE IN THIS LAST STUDY BACK 4291 02:28:03,440 --> 02:28:05,040 TO INCLUDE RACE BASED BIAS IN 4292 02:28:05,040 --> 02:28:05,640 SHOOTING. 4293 02:28:05,640 --> 02:28:07,840 WE'VE BEEN WORKING WITH A LAB IN 4294 02:28:07,840 --> 02:28:09,040 UNIVERSITY OF WASHINGTON WHO'S 4295 02:28:09,040 --> 02:28:13,880 DOING THIS WITH MUCH MORE HIGH 4296 02:28:13,880 --> 02:28:21,880 SOPHISTICATED EQUIPMENT AND -- K 4297 02:28:21,880 --> 02:28:23,000 THINGS TO LIKE A COMMUNITY 4298 02:28:23,000 --> 02:28:24,320 ADVISORY BOARD. 4299 02:28:24,320 --> 02:28:25,200 VERY LASTLY HUGE THANKS TO ALL 4300 02:28:25,200 --> 02:28:26,600 THE OFFICERS WHO PARTICIPATED IN 4301 02:28:26,600 --> 02:28:28,240 THIS, AND AGAIN TO ALL THE 4302 02:28:28,240 --> 02:28:29,680 PEOPLE, I'M JUST A SPOKESPERSON 4303 02:28:29,680 --> 02:28:31,840 REALLY FOR ALL THE WONDERFUL 4304 02:28:31,840 --> 02:28:34,920 PEOPLE WHO DID THIS WORK. 4305 02:28:34,920 --> 02:28:35,800 SO THANK YOU AGAIN. 4306 02:28:35,800 --> 02:28:36,560 I'LL TURN THIS BACK OVER. 4307 02:28:36,560 --> 02:28:38,000 >> THANK YOU SO MUCH, MIKE. 4308 02:28:38,000 --> 02:28:39,080 THAT WAS WONDERFUL. 4309 02:28:39,080 --> 02:28:40,280 I THINK WHAT WE'RE GOING TO DO 4310 02:28:40,280 --> 02:28:42,040 IS HOLD QUESTIONS UNTIL THE END, 4311 02:28:42,040 --> 02:28:44,080 JUST SO WE CAN GET THROUGH ALL 4312 02:28:44,080 --> 02:28:44,480 THE PRESENTATIONS. 4313 02:28:44,480 --> 02:28:46,960 SO PLEASE, ANYONE, ON THE CHAT 4314 02:28:46,960 --> 02:28:48,280 OR VIDEOCAST, PLEASE GO AHEAD 4315 02:28:48,280 --> 02:28:49,800 AND SUBMIT QUESTIONS IF YOU HAVE 4316 02:28:49,800 --> 02:28:51,040 THEM, ON ZOOM YOU CAN DO THAT 4317 02:28:51,040 --> 02:28:52,000 THROUGH CHAT AND I BELIEVE WE 4318 02:28:52,000 --> 02:28:55,840 HAVE A Q & A BOX OR AN EMAIL 4319 02:28:55,840 --> 02:28:57,280 UNDER THE VIDEOCAST WHERE YOU 4320 02:28:57,280 --> 02:28:59,160 CAN SUBMIT QUESTIONS. 4321 02:28:59,160 --> 02:29:01,200 BUT THANK YOU SO MUCH, MIKE, AND 4322 02:29:01,200 --> 02:29:04,920 I AM GOING TO TURN THINGS OVER 4323 02:29:04,920 --> 02:29:08,520 NOW TO OUR NEXT SPEAKER, WHO IS 4324 02:29:08,520 --> 02:29:09,840 ZEV SCHUMAN-OLIVIER. 4325 02:29:09,840 --> 02:29:11,160 SO ZEV, YOU'RE UP NEXT AND JUST 4326 02:29:11,160 --> 02:29:13,120 TELL ME "NEXT SLIDE" AND I'LL GO 4327 02:29:13,120 --> 02:29:14,440 AHEAD AND CLICK THROUGH FOR YOU. 4328 02:29:14,440 --> 02:29:14,840 >> GREAT. 4329 02:29:14,840 --> 02:29:15,440 THANK YOU. 4330 02:29:15,440 --> 02:29:17,080 AND MICHAEL, WHAT AN EXCITING 4331 02:29:17,080 --> 02:29:23,200 STUDY TO GET TO HEAR ABOUT. 4332 02:29:23,200 --> 02:29:24,520 I FEEL LUCKY TO BE ABLE TO HEAR 4333 02:29:24,520 --> 02:29:26,720 ABOUT IT SO EARLY HERE. 4334 02:29:26,720 --> 02:29:28,600 I'M ZEV SCHUMAN-OLIVIER, CENTER 4335 02:29:28,600 --> 02:29:30,440 FOR MINDFULNESS AND COMPASSION. 4336 02:29:30,440 --> 02:29:31,400 I'M GOING TO TELL YOU ABOUT A 4337 02:29:31,400 --> 02:29:33,600 PROJECT THAT REALLY IS MUCH 4338 02:29:33,600 --> 02:29:35,600 BIGGER THAN ME AND EVEN OUR 4339 02:29:35,600 --> 02:29:39,320 CENTER AND OUR ENTIRE HEALTHCARE 4340 02:29:39,320 --> 02:29:40,200 SYSTEM. 4341 02:29:40,200 --> 02:29:41,400 I WANT TO JUST THANK, BEFORE WE 4342 02:29:41,400 --> 02:29:46,000 GET STARTED, MANY OF OUR TEAM 4343 02:29:46,000 --> 02:29:48,720 MEMBERS WHO HELPED TO PUT 4344 02:29:48,720 --> 02:29:49,640 TOGETHER SOME OF THESE SLIDES 4345 02:29:49,640 --> 02:29:51,400 AND FIGURES FOR US AND I WANT TO 4346 02:29:51,400 --> 02:29:53,560 POINT OUT THAT IT REALLY HAS 4347 02:29:53,560 --> 02:29:54,040 TAKEN AN ENTIRE TEAM. 4348 02:29:54,040 --> 02:29:57,720 THIS IS OUR CURRENT TEAM RIGHT 4349 02:29:57,720 --> 02:30:06,800 HERE, AND CARL FULYILER IS WITH 4350 02:30:06,800 --> 02:30:08,480 ME ON THIS PROJECT, AND REALLY 4351 02:30:08,480 --> 02:30:10,200 WANT TO THANK THE OTHERS FOR 4352 02:30:10,200 --> 02:30:13,800 HELPING TO PUT TOGETHER. 4353 02:30:13,800 --> 02:30:20,280 SO LET'S KEEP GOING. 4354 02:30:20,280 --> 02:30:22,200 SO THIS PROJECT STARTED RIGHT AT 4355 02:30:22,200 --> 02:30:23,560 THE VERY BEGINNING OF COVID, 4356 02:30:23,560 --> 02:30:26,400 COVID-19, IN MARCH 2020. 4357 02:30:26,400 --> 02:30:29,360 AND WHAT WE PREDICTED MIGHT 4358 02:30:29,360 --> 02:30:30,360 HAPPEN IS WHAT HAPPENED, AND 4359 02:30:30,360 --> 02:30:32,760 THAT IS THAT THE PANDEMIC HAS 4360 02:30:32,760 --> 02:30:38,320 REALLY CAUSED A TSUNAMI OF 4361 02:30:38,320 --> 02:30:39,120 MENTAL HEALTH NEEDS. 4362 02:30:39,120 --> 02:30:41,640 SO STRESS, ANXIETY, DEPRESSION, 4363 02:30:41,640 --> 02:30:43,960 TRAUMA, GRIEF IS ABUNDANT, AND 4364 02:30:43,960 --> 02:30:46,160 NOT EVEN JUST FROM THE -- FROM 4365 02:30:46,160 --> 02:30:47,680 COVID ITSELF BUT ALL THE CHANGES 4366 02:30:47,680 --> 02:30:49,320 THAT RELATED TO IT, THE JOB 4367 02:30:49,320 --> 02:30:51,200 CHANGES, HOUSING CHANGES THAT 4368 02:30:51,200 --> 02:30:52,200 WENDY TALKED ABOUT BEFORE, 4369 02:30:52,200 --> 02:30:54,440 SOCIAL ISOLATION, CONTRACTING 4370 02:30:54,440 --> 02:30:56,440 COVID AND THE IMPACT OF THAT, 4371 02:30:56,440 --> 02:30:58,400 THE DELAY IN ROUTINE MEDICAL 4372 02:30:58,400 --> 02:31:00,160 PROCEDURES, THE IMPACT OF 4373 02:31:00,160 --> 02:31:01,560 PEOPLE'S HEALTH PROBLEMS, DEATH 4374 02:31:01,560 --> 02:31:03,880 OF LOVED ONES, THE RACIAL STRESS 4375 02:31:03,880 --> 02:31:06,720 AS MICHAEL POINTED OUT AND THEN 4376 02:31:06,720 --> 02:31:07,800 THE LOSS OF IDENTITY. 4377 02:31:07,800 --> 02:31:09,240 PEOPLE LEAVING JOBS TO CARE FOR 4378 02:31:09,240 --> 02:31:10,000 CHILDREN AT HOME, PEOPLE WORKING 4379 02:31:10,000 --> 02:31:11,560 FROM HOME, PEOPLE HAVING TO 4380 02:31:11,560 --> 02:31:13,400 RETURN HOME FROM SCHOOL AND FROM 4381 02:31:13,400 --> 02:31:14,760 AN ENVIRONMENT THEY WERE 4382 02:31:14,760 --> 02:31:16,920 COMFORTABLE IN TO NEEDING TO 4383 02:31:16,920 --> 02:31:19,440 HIDE THEIR IDENTITIES. 4384 02:31:19,440 --> 02:31:20,440 PEOPLE LAID OFF FROM WORK OR 4385 02:31:20,440 --> 02:31:21,200 HAVING TO TRANSITION. 4386 02:31:21,200 --> 02:31:30,240 A LOT OF STRESS ALL AROUND. 4387 02:31:30,240 --> 02:31:34,160 SO WE STARTED A PROJECT CALLED 4388 02:31:34,160 --> 02:31:35,320 CHA MINDWELL. 4389 02:31:35,320 --> 02:31:37,520 I JUST WANT TO SAY I'M REALLY 4390 02:31:37,520 --> 02:31:39,160 APPRECIATIVE TO THE CAMBRIDGE 4391 02:31:39,160 --> 02:31:40,360 HEALTH ALLIANCE EXECUTIVE TEAM 4392 02:31:40,360 --> 02:31:41,360 AND OUR PARTNER PSYCHIATRY 4393 02:31:41,360 --> 02:31:44,360 LEADERSHIP FOR REALLY KIND OF 4394 02:31:44,360 --> 02:31:46,160 GREEN LIGHTING SOMETHING IN THE 4395 02:31:46,160 --> 02:31:49,240 MIDST OF THE ACTIVE CHAOS AS THE 4396 02:31:49,240 --> 02:31:54,280 ENTIRE HOSPITAL WAS GOING INTO 4397 02:31:54,280 --> 02:31:56,680 EMERGENCY MODE TO BE ABLE TO 4398 02:31:56,680 --> 02:31:58,760 ALSO HAVE SOME FORESIGHT TO HAVE 4399 02:31:58,760 --> 02:32:00,680 SOMETHING TO BE ABLE TO WORK ON 4400 02:32:00,680 --> 02:32:02,800 THE MENTAL HEALTH CONSEQUENCES. 4401 02:32:02,800 --> 02:32:06,760 SO WE STARTED A FREE MENTAL 4402 02:32:06,760 --> 02:32:08,080 HEALTH WELLNESS PROGRAM TO 4403 02:32:08,080 --> 02:32:09,480 CONNECT THEM WITH SERVICES AND 4404 02:32:09,480 --> 02:32:11,040 AN ONLINE COMMUNITY. 4405 02:32:11,040 --> 02:32:12,920 BASICALLY PEOPLE GO ONLINE AND 4406 02:32:12,920 --> 02:32:14,960 THEY WERE USING COMPUTERIZED 4407 02:32:14,960 --> 02:32:16,960 ADAPTIVE TESTING FOR MENTAL 4408 02:32:16,960 --> 02:32:18,560 HEALTH AND COMPUTERIZED ADAPTIVE 4409 02:32:18,560 --> 02:32:19,880 TESTING FOR SOCIAL DETERMINANT 4410 02:32:19,880 --> 02:32:20,680 OF HEALTH. 4411 02:32:20,680 --> 02:32:22,840 AND WITH USING SEVEN DIFFERENT 4412 02:32:22,840 --> 02:32:24,600 MODULES, ASSESSING THEIR MENTAL 4413 02:32:24,600 --> 02:32:26,680 HEALTH, ANXIETY, DEPRESSION, 4414 02:32:26,680 --> 02:32:30,040 PTSD, ADHD, MANIA/HYPOMANIA, 4415 02:32:30,040 --> 02:32:32,080 JUST AS AN EXAMPLE OF SOME OF 4416 02:32:32,080 --> 02:32:36,960 THE MODULES. 4417 02:32:36,960 --> 02:32:39,160 WE DO THAT AT BASELINE WHEN THEY 4418 02:32:39,160 --> 02:32:42,440 REGISTER AT ENROLLMENT, WE DO IT 4419 02:32:42,440 --> 02:32:44,760 AT ONE MONTH, TWO MONTHS, THREE 4420 02:32:44,760 --> 02:32:46,320 MONTHS, FOUR MONTHS, SIX AND 4421 02:32:46,320 --> 02:32:47,520 NINE MONTHS AND 12 MONTHS. 4422 02:32:47,520 --> 02:32:57,000 WE'RE AND WHEN PEOPLE'S DATA , 4423 02:32:57,000 --> 02:32:59,200 WE THEN HAVE A PROCESS AND 4424 02:32:59,200 --> 02:33:01,040 ALGORITHM FOR TIERING PEOPLE. 4425 02:33:01,040 --> 02:33:03,040 SO TIER ONE, PEOPLE WITH NO OR 4426 02:33:03,040 --> 02:33:04,960 MINIMAL SYMPTOMS, TIER TWO WITH 4427 02:33:04,960 --> 02:33:09,360 MILD OR MODERATE SYMPTOMS, AND 4428 02:33:09,360 --> 02:33:10,560 THEN TIER THREE WAS SEVERE 4429 02:33:10,560 --> 02:33:11,080 SYMPTOMS. 4430 02:33:11,080 --> 02:33:12,400 SO IF YOU THINK ABOUT IT THIS 4431 02:33:12,400 --> 02:33:18,000 WAY, BASED ON WHAT PEOPLE'S TIER 4432 02:33:18,000 --> 02:33:19,520 WAS WE COULD GIVE THEM 4433 02:33:19,520 --> 02:33:20,360 PERSONALIZED RECOMMENDATIONS FOR 4434 02:33:20,360 --> 02:33:22,720 WHAT THEY NEED NEEDED. 4435 02:33:22,720 --> 02:33:24,240 SO EVERYONE HAD ACCESS TO A 4436 02:33:24,240 --> 02:33:25,720 MONTHLY NEWSLETTER ON MENTAL 4437 02:33:25,720 --> 02:33:26,760 HEALTH TOPICS. 4438 02:33:26,760 --> 02:33:29,000 WE GAVE MENTAL ILLNESS 4439 02:33:29,000 --> 02:33:31,000 PROGRAMMING WITH A COORDINATOR, 4440 02:33:31,000 --> 02:33:34,080 GIVE THEM ADVICE ON SELF-HELP 4441 02:33:34,080 --> 02:33:36,200 MOBILE APPS, ESPECIALLY FOR THE 4442 02:33:36,200 --> 02:33:40,120 TIER 1 FOLKS THAT WERE IN TIER 4443 02:33:40,120 --> 02:33:40,240 1. 4444 02:33:40,240 --> 02:33:42,960 THEN PEOPLE WOULD ALSO GET EMAIL 4445 02:33:42,960 --> 02:33:44,920 OR PHONE COACHING AROUND 4446 02:33:44,920 --> 02:33:46,480 ACTIVATING AND USING THE 4447 02:33:46,480 --> 02:33:48,200 RESOURCES THAT WERE IN THE 4448 02:33:48,200 --> 02:33:48,520 PROGRAM. 4449 02:33:48,520 --> 02:33:50,840 WE TRAINED ALL OF OUR STAFF IN 4450 02:33:50,840 --> 02:33:55,000 MOTIVATIONAL INTERVIEWING BY A 4451 02:33:55,000 --> 02:33:55,960 CERTIFIED MOTIVATIONAL 4452 02:33:55,960 --> 02:33:58,560 TRAININGER SO ALL 4453 02:33:58,560 --> 02:34:00,240 TRAININGER SO OUR COORDINATORS 4454 02:34:00,240 --> 02:34:02,200 KNEW HOW TO TALK TO PEOPLE ABOUT 4455 02:34:02,200 --> 02:34:04,200 ACTIVATING AND MAKING BEHAVIOR 4456 02:34:04,200 --> 02:34:07,600 CHANGE IN ENGAGING WITH THE SELF 4457 02:34:07,600 --> 02:34:10,240 HELP APPS, LIVE ONLINE, 4458 02:34:10,240 --> 02:34:11,640 MINDFULNESS PROGRAMS, AND WE 4459 02:34:11,640 --> 02:34:14,000 MADE IT AVAILABLE FOR ANYONE IN 4460 02:34:14,000 --> 02:34:15,800 THE PROGRAM TO JOIN A FREE 4461 02:34:15,800 --> 02:34:16,800 MINDFULNESS COURSE THAT WAS 4462 02:34:16,800 --> 02:34:17,080 AVAILABLE. 4463 02:34:17,080 --> 02:34:22,040 WE HAD THINGS LIKE MBSR, STRESS 4464 02:34:22,040 --> 02:34:25,520 REDUCTION, COGNITIVE THERAPY FOR 4465 02:34:25,520 --> 02:34:27,600 RESILIENCE, MINDFULNESS TRAINING 4466 02:34:27,600 --> 02:34:29,960 FOR LIVING WELL, AND FOR SELF 4467 02:34:29,960 --> 02:34:30,720 COMPASSION GROUPS. 4468 02:34:30,720 --> 02:34:34,960 FOR THOSE WHO WERE IN TIER IT OR 4469 02:34:34,960 --> 02:34:36,080 TIER 3, THERE WAS AN OPPORTUNITY 4470 02:34:36,080 --> 02:34:38,680 TO MEET AND DO A PHONE OR VIDEO 4471 02:34:38,680 --> 02:34:40,560 CHECK-IN WITH A MENTAL WELLNESS 4472 02:34:40,560 --> 02:34:42,320 SPECIALIST WHO WAS A CLINICIAN, 4473 02:34:42,320 --> 02:34:44,840 CLINICALLY TRAINED CLINICIAN WHO 4474 02:34:44,840 --> 02:34:48,680 COULD DO A BRIEF TRIAGE AND 4475 02:34:48,680 --> 02:34:49,680 ASSESSMENT AND EVALUATE WHETHER 4476 02:34:49,680 --> 02:34:50,720 OR NOT PEOPLE NEEDED A HIGHER 4477 02:34:50,720 --> 02:34:53,120 LEVEL OF CARE OR NOT. 4478 02:34:53,120 --> 02:34:54,680 AND SO THEY WERE ABLE TO THEN 4479 02:34:54,680 --> 02:34:56,120 MAKE REFERRALS TO ADDITIONAL 4480 02:34:56,120 --> 02:34:57,000 CLINICAL CARE AS NEEDED. 4481 02:34:57,000 --> 02:34:58,160 IT IMPORTANT TO SAY THAT DURING 4482 02:34:58,160 --> 02:35:01,560 THIS TIME OVER COVID, OUR WAIT 4483 02:35:01,560 --> 02:35:04,080 LIST OUTPATIENT CARE WAS IN THE 4484 02:35:04,080 --> 02:35:04,360 THOUSANDS. 4485 02:35:04,360 --> 02:35:05,760 AS FAR AS PEOPLE SEEKING MENTAL 4486 02:35:05,760 --> 02:35:06,160 HEALTHCARE. 4487 02:35:06,160 --> 02:35:08,680 SO THE IDEA THAT PEOPLE COULD BE 4488 02:35:08,680 --> 02:35:11,000 ABLE TO ASSESS RAPIDLY IN THIS 4489 02:35:11,000 --> 02:35:13,400 AUTOMATED WAY AND BE ABLE TO GET 4490 02:35:13,400 --> 02:35:15,360 TRIAGE TO PEOPLE THAT REALLY 4491 02:35:15,360 --> 02:35:17,040 NEED SUPPORT RIGHT AWAY WAS 4492 02:35:17,040 --> 02:35:18,560 REALLY A GREAT PART OF THIS 4493 02:35:18,560 --> 02:35:19,080 PROGRAM. 4494 02:35:19,080 --> 02:35:25,560 SO NEXT SLIDE, PLEASE. 4495 02:35:25,560 --> 02:35:26,440 THIS BASELINE STARTED IN APRIL, 4496 02:35:26,440 --> 02:35:31,680 SO ABOUT THREE WEEKS AFTER THE 4497 02:35:31,680 --> 02:35:33,520 COVID LOCK DOWNS STARTED HERE IN 4498 02:35:33,520 --> 02:35:33,760 BOSTON. 4499 02:35:33,760 --> 02:35:36,960 WE MOVED QUICKLY, IN ABOUT 10 4500 02:35:36,960 --> 02:35:38,560 DAYS, AND STARTED A QUALITY 4501 02:35:38,560 --> 02:35:40,320 IMPROVEMENT PROJECT WHERE WE 4502 02:35:40,320 --> 02:35:44,400 STARTED MINDWELL WITH CAT-MH AND 4503 02:35:44,400 --> 02:35:46,440 WE GOT ANXIETY AND DEPRESSION 4504 02:35:46,440 --> 02:35:47,760 SCORES FOR EIGHT WEEKS IN A ROW 4505 02:35:47,760 --> 02:35:50,040 AND EVERYBODY IN THIS CASE WAS 4506 02:35:50,040 --> 02:35:51,320 ENROLLED OR OFFERED TO ENROLL IN 4507 02:35:51,320 --> 02:35:53,240 THE MINDFULNESS BASED COGNITIVE 4508 02:35:53,240 --> 02:35:53,800 THERAPY PROGRAM. 4509 02:35:53,800 --> 02:35:55,360 AND YOU CAN SEE HERE THAT EVEN 4510 02:35:55,360 --> 02:36:00,280 IN THAT VERY FIRST ITERATION, WE 4511 02:36:00,280 --> 02:36:01,880 SAW A 41% REDUCTION IN ANXIE%Y 4512 02:36:01,880 --> 02:36:04,680 AND 34% REDUCTION IN DEPRESSIVE 4513 02:36:04,680 --> 02:36:05,840 SYMPTOMS DURING THIS HEART OF 4514 02:36:05,840 --> 02:36:08,480 THE COVID LOCKDOWN. 4515 02:36:08,480 --> 02:36:10,560 WHICH SUGGESTED THAT WE WERE ON 4516 02:36:10,560 --> 02:36:11,800 TO SOMETHING AND WE REALLY 4517 02:36:11,800 --> 02:36:19,000 SHOULD PURSUE THIS FURTHER. 4518 02:36:19,000 --> 02:36:21,080 WHAT WE BUILT, WE HAD THIS IDEA 4519 02:36:21,080 --> 02:36:23,680 IN ORDER FOR TO BE REALLY 4520 02:36:23,680 --> 02:36:25,440 IMPACTFUL FOR US AND OTHER 4521 02:36:25,440 --> 02:36:26,440 HEALTHCARE SYSTEMS EVENTUALLY, 4522 02:36:26,440 --> 02:36:28,720 WE WANTED TO BE ABLE TO 4523 02:36:28,720 --> 02:36:30,360 INTEGRATE THIS TESTING DEVELOPED 4524 02:36:30,360 --> 02:36:32,280 BY ADAPTIVE TESTING TECHNOLOGIES 4525 02:36:32,280 --> 02:36:35,720 THROUGH AN FBR GRANT WITH NIMH. 4526 02:36:35,720 --> 02:36:37,920 WE WANTED TO BE ABLE TO 4527 02:36:37,920 --> 02:36:40,120 INTEGRATE THIS INTO RED CAP. 4528 02:36:40,120 --> 02:36:41,720 THERE WAS BEGINNING TO BE CODE 4529 02:36:41,720 --> 02:36:43,520 AROUND AN EXTERNAL MODULE THAT 4530 02:36:43,520 --> 02:36:48,120 WAS DEVELOPED AT VANDERBILT IN A 4531 02:36:48,120 --> 02:36:49,640 PROGRAM WITH CARL REID, SO WE 4532 02:36:49,640 --> 02:36:51,720 STARTED WORKING WITH CARL TO 4533 02:36:51,720 --> 02:36:53,280 GIVE US HIGH LEVELS OF 4534 02:36:53,280 --> 02:36:55,200 PROCESSING TO BE ABLE TO GET 4535 02:36:55,200 --> 02:36:56,880 PEOPLE'S SEVERITY, RESPONSES TO 4536 02:36:56,880 --> 02:37:00,240 BE ABLE TO SEE WHAT CATEGORY 4537 02:37:00,240 --> 02:37:02,560 THEY'RE IN AND THEN BE ABLE TO 4538 02:37:02,560 --> 02:37:04,960 TIER THEM AND THEN SCHEDULE THEM 4539 02:37:04,960 --> 02:37:08,720 FOR APPOINTMENTS IF NEEDED OR 4540 02:37:08,720 --> 02:37:09,600 MOVE THEM ALONG. 4541 02:37:09,600 --> 02:37:12,800 YOU CAN SEE HERE THIS IS JUST AN 4542 02:37:12,800 --> 02:37:14,000 EXAMPLE TEST HOW FOR EACH 4543 02:37:14,000 --> 02:37:15,200 DIFFERENT TYPE OF ASPECT OF 4544 02:37:15,200 --> 02:37:18,160 MENTAL WELLNESS, DEPRESSION, 4545 02:37:18,160 --> 02:37:21,120 ANXIETY, MANIA, SUBSTANCE USE, 4546 02:37:21,120 --> 02:37:22,680 PSYCHOSIS, ADD AND SOCIAL 4547 02:37:22,680 --> 02:37:23,840 DETERMINANTS OF HEALTH, WE WERE 4548 02:37:23,840 --> 02:37:27,600 ABLE TO GET A HIGH PRECISION 4549 02:37:27,600 --> 02:37:28,480 SCORE AND ASSESS THEIR TIER 4550 02:37:28,480 --> 02:37:28,920 LEVEL. 4551 02:37:28,920 --> 02:37:32,200 THIS EXTERNAL MODULE ACTUALLY IS 4552 02:37:32,200 --> 02:37:34,240 AVAILABLE ON GITHUB IF YOU WANT 4553 02:37:34,240 --> 02:37:36,760 TO BRING THIS INTO YOUR OWN RED 4554 02:37:36,760 --> 02:37:39,840 CAP DATABASE. 4555 02:37:39,840 --> 02:37:42,560 SO WE GOT READY, WE DID FOCUS 4556 02:37:42,560 --> 02:37:43,960 GROUPS WITH THE NEW SYSTEM THAT 4557 02:37:43,960 --> 02:37:46,520 WAS MORE AUTOMATED USING RED CAP 4558 02:37:46,520 --> 02:37:50,440 IN THE SUMMER AND FALL OF 2020 , 4559 02:37:50,440 --> 02:37:56,040 AND THEN WE SUBMITTED NIH 4560 02:37:56,040 --> 02:37:58,560 SUPPLEMENT TO ANOTHER R33 GRANT, 4561 02:37:58,560 --> 02:38:00,280 AND WE WERE WAITING FOR THAT AND 4562 02:38:00,280 --> 02:38:03,520 I WANT TO EXPRESS MY GRATITUDE 4563 02:38:03,520 --> 02:38:05,440 TOLY 4564 02:38:05,440 --> 02:38:10,480 TO LENNAE, ROBYN AND WEN DEEP 4565 02:38:10,480 --> 02:38:11,880 THROUGH CHAOTIC TIMES TO HELPING 4566 02:38:11,880 --> 02:38:12,680 MOVE THIS PROJECT ALONG. 4567 02:38:12,680 --> 02:38:14,840 SO FINALLY IT WAS APPROVED 4568 02:38:14,840 --> 02:38:19,440 FOR -- IN EARLY FALL. 4569 02:38:19,440 --> 02:38:20,520 UNFORTUNATELY -- WE WANTED TO 4570 02:38:20,520 --> 02:38:25,440 PUT AN RTC TO LOOK AT THE 4571 02:38:25,440 --> 02:38:26,680 DIFFERENCES OF HOW RANDOMIZED 4572 02:38:26,680 --> 02:38:29,040 PEOPLE TO DIFFERENT ARMS AND 4573 02:38:29,040 --> 02:38:29,840 INTERVENTIONS WOULD WORK AND 4574 02:38:29,840 --> 02:38:31,680 THERE WERE SUBSTANTIAL COVID 4575 02:38:31,680 --> 02:38:32,360 DELAYS. 4576 02:38:32,360 --> 02:38:36,520 THE MINDWELL-READ CAP STARTED IN 4577 02:38:36,520 --> 02:38:38,840 2020, AND IN DECEMBER AND I HAVE 4578 02:38:38,840 --> 02:38:40,560 TO SAY IT WAS AN INCREDIBLY 4579 02:38:40,560 --> 02:38:42,440 DIFFICULT TIME WITH THESE 4580 02:38:42,440 --> 02:38:45,920 BUILDING LEVELS, RACIAL STRESS, 4581 02:38:45,920 --> 02:38:46,880 POLITICAL POLARIZATION. 4582 02:38:46,880 --> 02:38:49,720 SO IN EARLY JANUARY, WE ACTUALLY 4583 02:38:49,720 --> 02:38:54,080 HAD TO STOP OUR IMPLEMENTATION 4584 02:38:54,080 --> 02:38:56,120 FOCUS ON MAINTAINING STAFF AND 4585 02:38:56,120 --> 02:38:58,160 THE STAFF'S MENTAL WELLNESS 4586 02:38:58,160 --> 02:38:59,760 DURING THE COLLECTIVE 4587 02:38:59,760 --> 02:39:01,760 DIFFICULTIES THAT ARE HAPPENING 4588 02:39:01,760 --> 02:39:04,080 IN EARLY JANUARY, AND THROUGH 4589 02:39:04,080 --> 02:39:05,960 MID MARCH AND FINALLY WE'RE ABLE 4590 02:39:05,960 --> 02:39:08,480 TO GET IRB APPROVALS AND CHANGE 4591 02:39:08,480 --> 02:39:11,440 IN STAFF ON THE IRB SO WE MOVE 4592 02:39:11,440 --> 02:39:11,880 FORWARD. 4593 02:39:11,880 --> 02:39:13,480 I THINK OF THIS AS REALLY 4594 02:39:13,480 --> 02:39:14,920 PUTTING OUR MASKS ON FIRST TO 4595 02:39:14,920 --> 02:39:17,560 DEAL WITH ALL THE INTERNAL 4596 02:39:17,560 --> 02:39:18,160 IMPACTS, EVERYTHING THAT WAS 4597 02:39:18,160 --> 02:39:21,080 GOING ON AND STABILIZE THEIR 4598 02:39:21,080 --> 02:39:21,920 SYSTEM. 4599 02:39:21,920 --> 02:39:23,720 SO EVEN TAKING THAT TIME TO 4600 02:39:23,720 --> 02:39:24,800 STABILIZE OURSELVES DIDN'T 4601 02:39:24,800 --> 02:39:26,040 REALLY PREPARE US FOR WHAT 4602 02:39:26,040 --> 02:39:30,520 WASSING WHAT WHAT WAS 4603 02:39:30,520 --> 02:39:31,240 ABOUT TO COME. 4604 02:39:31,240 --> 02:39:32,680 WHEN WE FINALLY REALLY OPENED 4605 02:39:32,680 --> 02:39:34,560 THE GATES WIDE TO BE ABLE TO 4606 02:39:34,560 --> 02:39:37,840 ALLOW PEOPLE TO START ENROLLING 4607 02:39:37,840 --> 02:39:42,040 FOR CHAMINDWELL, WE GOT 200 4608 02:39:42,040 --> 02:39:46,960 ENROLLMENTS LITERALLY IN 24 4609 02:39:46,960 --> 02:39:48,680 HOURS. 4610 02:39:48,680 --> 02:39:51,280 AND OUR SYSTEM WAS DESIGNED TO 4611 02:39:51,280 --> 02:39:52,680 HAVE 20 TO 30 A WEEK. 4612 02:39:52,680 --> 02:39:56,680 SO WE NEED LE HAD TO SHUT DOWN T 4613 02:39:56,680 --> 02:39:59,360 DOWN THE PROGRAM AGAIN AND SHUT 4614 02:39:59,360 --> 02:40:01,480 THE DOOR BECAUSE THE NEEDS WERE 4615 02:40:01,480 --> 02:40:01,920 SO INTENSE. 4616 02:40:01,920 --> 02:40:03,960 AFTER A MONTH OR TWO OF 4617 02:40:03,960 --> 02:40:04,680 REORGANIZING, WE OPENED AGAIN 4618 02:40:04,680 --> 02:40:06,600 AND YOU CAN SEE AGAIN JUNE 4619 02:40:06,600 --> 02:40:07,560 THROUGH SEPTEMBER, VERY QUICKLY 4620 02:40:07,560 --> 02:40:10,000 THE POPULATION STRESS EVEN AFTER 4621 02:40:10,000 --> 02:40:12,520 THE COVID WAVE HAD PASSED IN 4622 02:40:12,520 --> 02:40:15,000 JANUARY AND FEBRUARY WAS STILL 4623 02:40:15,000 --> 02:40:16,120 VERY MUCH THERE FOR THE SUMMER. 4624 02:40:16,120 --> 02:40:19,080 AND WE ACTUALLY HAD TO CLOSE AND 4625 02:40:19,080 --> 02:40:20,040 LIMIT ENROLLMENT AGAIN BECAUSE 4626 02:40:20,040 --> 02:40:24,320 OF THE INTENSITY. 4627 02:40:24,320 --> 02:40:25,440 WE OPENED UP AGAIN IN OCTOBER 4628 02:40:25,440 --> 02:40:26,840 AND WE'VE BEEN ABLE TO MAINTAIN 4629 02:40:26,840 --> 02:40:35,400 A PRETTY STEADY FLOW SINCE THEN. 4630 02:40:35,400 --> 02:40:38,880 SO WE WERE FUNDED TO RUN A RCT 4631 02:40:38,880 --> 02:40:42,600 WITHIN THE CONTEXT OF THE 4632 02:40:42,600 --> 02:40:44,680 CHAMINDWELL IMPLEMENTATION 4633 02:40:44,680 --> 02:40:45,640 PROJECT. 4634 02:40:45,640 --> 02:40:49,280 AND IT WAS COMPARATIVE 4635 02:40:49,280 --> 02:40:54,440 EFFECTIVENESS RCT COMPARING 4636 02:40:54,440 --> 02:40:56,640 COGNITIVE BASED THERAPY PLUS THE 4637 02:40:56,640 --> 02:41:02,080 MINDWELL MONITORING AND COACHING 4638 02:41:02,080 --> 02:41:03,760 VERSUS INTERNET CBT WHERE WE 4639 02:41:03,760 --> 02:41:06,920 USED THE SIX WEEK ASYNCHRONOUS 4640 02:41:06,920 --> 02:41:10,240 MOOD GYM CURRICULUM AS OUR 4641 02:41:10,240 --> 02:41:12,200 ACTIVE CONTROL GROUP, AND THEN 4642 02:41:12,200 --> 02:41:17,000 WE ALSO HAD AS ANOTHER CONTROL 4643 02:41:17,000 --> 02:41:19,320 ARM JUST CHAMINDWELL ALONE. 4644 02:41:19,320 --> 02:41:22,000 SPECIFICALLY WE WERE LOOKING AT 4645 02:41:22,000 --> 02:41:26,480 THE PRIMARY OUTCOMES, LEVELS OF 4646 02:41:26,480 --> 02:41:27,720 DEPRESSIVE SYMPTOMS, AT 24 4647 02:41:27,720 --> 02:41:30,680 WEEKS, SUBSTANCE USE, AND 4648 02:41:30,680 --> 02:41:31,480 UTILIZATION OF TELEVISITS DURING 4649 02:41:31,480 --> 02:41:37,720 THIS TIME. 4650 02:41:37,720 --> 02:41:39,880 THIS WAS THE STUDY FORMAT, 4651 02:41:39,880 --> 02:41:40,920 RANDOMIZING TO THREE DIFFERENT 4652 02:41:40,920 --> 02:41:41,160 ARMS. 4653 02:41:41,160 --> 02:41:44,000 WE CONTINUE TO DO CAT-MH EVERY 4654 02:41:44,000 --> 02:41:52,680 FOUR WEEKS THROUGHOUT THE STUDY. 4655 02:41:52,680 --> 02:41:55,160 WE ALSO HAD A SALIVARY SUBSTUDY 4656 02:41:55,160 --> 02:41:57,200 WHERE WE WANTED TO LOOK AT THE 4657 02:41:57,200 --> 02:41:58,960 RELATIONSHIP BETWEEN DAILY 4658 02:41:58,960 --> 02:42:01,640 STRESS AND AFFECT AS RECORDED ON 4659 02:42:01,640 --> 02:42:02,880 AFFECT DIARIES THAT WERE 4660 02:42:02,880 --> 02:42:06,600 DEVELOPED AT PENN STATE 4661 02:42:06,600 --> 02:42:07,480 UNIVERSITY. 4662 02:42:07,480 --> 02:42:08,680 AND WE WERE LOOKING AT DIFFERENT 4663 02:42:08,680 --> 02:42:11,760 TYPES OF STRESS INCLUDING STRESS 4664 02:42:11,760 --> 02:42:13,400 RELATED TO COVID-19. 4665 02:42:13,400 --> 02:42:15,320 AND THEN TO LOOK AT THE 4666 02:42:15,320 --> 02:42:17,440 RELATIONSHIP BETWEEN STRESS AND 4667 02:42:17,440 --> 02:42:21,280 POSITIVE AND NEGATIVE AFFECT 4668 02:42:21,280 --> 02:42:25,200 DAYS WITH ESPECIALLY IL-6, 4669 02:42:25,200 --> 02:42:26,080 INTERLEUKIN-6, WHICH HAS BEEN 4670 02:42:26,080 --> 02:42:28,040 DEMONSTRATED TO BE LINKED -- OR 4671 02:42:28,040 --> 02:42:30,240 ASSOCIATED WITH DEPRESSION AND 4672 02:42:30,240 --> 02:42:31,120 THERE'S SOME PRELIMINARY DATA 4673 02:42:31,120 --> 02:42:33,760 SUGGESTING THAT IT MAY BE 4674 02:42:33,760 --> 02:42:34,920 NEGATIVELY ASSOCIATED WITH 4675 02:42:34,920 --> 02:42:36,920 POSITIVE AFFECT. 4676 02:42:36,920 --> 02:42:39,080 SO WE'RE PLANNING TO GATHER 4677 02:42:39,080 --> 02:42:43,480 THAT'S DATA BEFORE AND AFTER THE 4678 02:42:43,480 --> 02:42:45,320 INTERVENTION PERIOD OF THE FIRST 4679 02:42:45,320 --> 02:42:50,560 EIGHT WEEKS. 4680 02:42:50,560 --> 02:42:52,120 UNFORTUNATELY SALIVA BECAME 4681 02:42:52,120 --> 02:42:53,520 CLASSIFIED AS A CATEGORY B 4682 02:42:53,520 --> 02:42:54,400 SUBSTANCE DUE TO COVID-19 AS WE 4683 02:42:54,400 --> 02:42:56,400 WERE GETTING READY TO LAUNCH THE 4684 02:42:56,400 --> 02:42:57,960 STUDY, SO WE ACTUALLY HAD TO GO 4685 02:42:57,960 --> 02:43:00,240 THROUGH MULTIPLE LAYERS OF 4686 02:43:00,240 --> 02:43:01,880 SAFETY REVIEW SO WE WEREN'T ABLE 4687 02:43:01,880 --> 02:43:06,400 TO IMPLEMENT THE SALIVARY STUDY 4688 02:43:06,400 --> 02:43:07,240 UNTIL HALFWAY THROUGH THE STUDY. 4689 02:43:07,240 --> 02:43:08,880 SO IT'S ONGOING NOW BUT THAT WAS 4690 02:43:08,880 --> 02:43:09,880 A LIMITATION OF WORKING IN THIS 4691 02:43:09,880 --> 02:43:11,680 CON 4692 02:43:11,680 --> 02:43:14,880 CONTEXT. 4693 02:43:14,880 --> 02:43:18,240 SO I WANT TO SHARE SOME OF OUR 4694 02:43:18,240 --> 02:43:19,520 DATA FROM THE MINDWELL PROJECT 4695 02:43:19,520 --> 02:43:22,160 WHICH IS THIS POPULATION MENTAL 4696 02:43:22,160 --> 02:43:24,920 WELLNESS PROJECT. 4697 02:43:24,920 --> 02:43:27,320 WE REALLY ARE FIGHTING AGAINST 4698 02:43:27,320 --> 02:43:27,840 THE TIDE HERE. 4699 02:43:27,840 --> 02:43:30,040 IF YOU LOOK AT THOSE YELLOW 4700 02:43:30,040 --> 02:43:32,000 LINES ON THE LEFT, THOSE ARE THE 4701 02:43:32,000 --> 02:43:34,400 LEVELS IN 2019 OF ANXIETY 4702 02:43:34,400 --> 02:43:36,680 DISORDER, DEPRESSIVE DISORDER OR 4703 02:43:36,680 --> 02:43:38,120 ANXIETY AND DEPRESSION, AND YOU 4704 02:43:38,120 --> 02:43:40,000 CAN SEE THAT ALTHOUGH THE 4705 02:43:40,000 --> 02:43:41,840 BIGGEST INCREASE IN ANXIETY AND 4706 02:43:41,840 --> 02:43:44,680 DEPRESSION HAPPENED BETWEEN JUNE 4707 02:43:44,680 --> 02:43:46,320 AND DECEMBER 2020, THAT IT HAS 4708 02:43:46,320 --> 02:43:48,640 NOT GONE BACK TO BASELINE AND, 4709 02:43:48,640 --> 02:43:50,280 IN FACT, WE STILL ARE ABOUT 4710 02:43:50,280 --> 02:43:54,120 THREE TIMES THE LEVEL OF 4711 02:43:54,120 --> 02:43:55,360 ANXIETY/DEPRESSION THAT WE WERE 4712 02:43:55,360 --> 02:43:56,200 SEEING PRE-PANDEMIC. 4713 02:43:56,200 --> 02:43:57,880 SO I JUST WANT TO KEEP THAT IN 4714 02:43:57,880 --> 02:43:58,400 MIND. 4715 02:43:58,400 --> 02:43:59,840 OUR GOAL WAS JUST TO HOPE THAT 4716 02:43:59,840 --> 02:44:01,480 WE WERE KEEPING PEOPLE THAT WERE 4717 02:44:01,480 --> 02:44:04,520 ENROLLED IN OUR POPULATION 4718 02:44:04,520 --> 02:44:05,320 WELLNESS PROGRAM WITHOUT CHANGE, 4719 02:44:05,320 --> 02:44:07,600 WITHOUT THIS MASSIVE INCREASE, 4720 02:44:07,600 --> 02:44:10,240 BUT THE REST OF THE COUNTRY IS 4721 02:44:10,240 --> 02:44:13,200 EXPERIENCING. 4722 02:44:13,200 --> 02:44:16,280 THIS IS DATA FROM OUR FIRST 4723 02:44:16,280 --> 02:44:19,640 921 R 4724 02:44:19,640 --> 02:44:20,280 921 PATIENTS THAT ENROLLED IN 4725 02:44:20,280 --> 02:44:20,720 THE PROGRAM. 4726 02:44:20,720 --> 02:44:22,040 ONE OF THE GOALS WAS THAT WE 4727 02:44:22,040 --> 02:44:23,920 WOULD HAVE PEOPLE ENROLL IN A 4728 02:44:23,920 --> 02:44:25,520 WAY THAT WOULD NOT CREATE ANY 4729 02:44:25,520 --> 02:44:28,160 EQUITY ISSUES OR DISPARITIES. 4730 02:44:28,160 --> 02:44:30,440 THAT WAS A REALLY IMPORTANT PART 4731 02:44:30,440 --> 02:44:33,760 OF TESTING OUT THE FEASIBILITY 4732 02:44:33,760 --> 02:44:34,960 APPROACH GIVEN THAT IT IS 4733 02:44:34,960 --> 02:44:36,720 INTEGRATING WITH TECHNOLOGY AND 4734 02:44:36,720 --> 02:44:40,040 WHEN WE STARTED IN THE FIRST 4735 02:44:40,040 --> 02:44:42,040 YEAR, WE WERE PRIMARILY USING 4736 02:44:42,040 --> 02:44:44,120 ENGLISH BASED PROGRAMS, ALTHOUGH 4737 02:44:44,120 --> 02:44:47,320 WE ARE GETTING READY TO LAUNCH A 4738 02:44:47,320 --> 02:44:48,640 SPANISH BASED PROGRAM AS WELL. 4739 02:44:48,640 --> 02:44:50,680 AS YOU CAN SEE, THE RACIAL AND 4740 02:44:50,680 --> 02:44:52,120 ETHNIC BREAKDOWN OF OUR SERVICE 4741 02:44:52,120 --> 02:44:53,800 AREA IS BASICALLY REFLECTED IN 4742 02:44:53,800 --> 02:44:56,080 THE PEOPLE WHO COMPLETED 4743 02:44:56,080 --> 02:44:56,680 MINDWELL. 4744 02:44:56,680 --> 02:45:00,200 SO THERE WAS NO DISPARITY IN 4745 02:45:00,200 --> 02:45:02,960 ENROLLMENT AND WHEN WE DO HIGH 4746 02:45:02,960 --> 02:45:07,200 SCORE ANALYSIS, THERE WAS NO 4747 02:45:07,200 --> 02:45:07,880 STATISTICALLY SIGNIFICANT 4748 02:45:07,880 --> 02:45:11,920 DIFFERENCE IN THOSE WHO ALSO 4749 02:45:11,920 --> 02:45:14,560 COMPLETED. 4750 02:45:14,560 --> 02:45:16,680 >> ZEV, WE'VE PROBABLY GOT ABOUT 4751 02:45:16,680 --> 02:45:18,720 TWO OR THREE MINUTES. 4752 02:45:18,720 --> 02:45:20,880 >> I'LL GO THROUGH THESE LAST 4753 02:45:20,880 --> 02:45:21,320 ONES PRETTY FAST. 4754 02:45:21,320 --> 02:45:25,320 IT WAS PRIMARILY MORE FEMALE 4755 02:45:25,320 --> 02:45:32,680 ENROLLING IN THIS PROGRAM. 4756 02:45:32,680 --> 02:45:34,160 YOU CAN SEE ANXIETY ON RIGHT ARE 4757 02:45:34,160 --> 02:45:37,040 PEOPLE WHO HAD TIER TWO OR TIER 4758 02:45:37,040 --> 02:45:38,360 THREE LEVEL SCORES, AND YOU CAN 4759 02:45:38,360 --> 02:45:42,160 SEE THAT WE DID HAVE SIGNIFICANT 4760 02:45:42,160 --> 02:45:44,680 REDUCTION IN ANXIETY SCORES AT 4761 02:45:44,680 --> 02:45:46,320 BASELINE COMPARED TO THE 4762 02:45:46,320 --> 02:45:48,320 FOLLOW-UP TIME POINT. 4763 02:45:48,320 --> 02:45:53,560 IN ANXIETY. 4764 02:45:53,560 --> 02:45:54,640 IF YOU LOOK AT THE RIGHT AS 4765 02:45:54,640 --> 02:45:59,760 WELL, YOU CAN SEE FOR ALL PTSD 4766 02:45:59,760 --> 02:46:00,880 SCORES ESPECIALLY THOSE THAT 4767 02:46:00,880 --> 02:46:03,080 REACHED A TIER 2 OR TIER 4768 02:46:03,080 --> 02:46:05,120 3 LEVEL, WE HAD SIGNIFICANT 4769 02:46:05,120 --> 02:46:08,440 REDUCTIONS IN PTSD SCORES OVER 4770 02:46:08,440 --> 02:46:13,920 TIME AND SYMPTOMS, AND -- I'M 4771 02:46:13,920 --> 02:46:15,120 SORRY, THIS IS DEPRESSION. 4772 02:46:15,120 --> 02:46:16,440 WE SEE THE SAME THING WITH 4773 02:46:16,440 --> 02:46:16,880 DEPRESSION. 4774 02:46:16,880 --> 02:46:18,960 SO SAME PATTERN ACROSS ALL OF 4775 02:46:18,960 --> 02:46:19,400 THOSE. 4776 02:46:19,400 --> 02:46:22,040 AND FINALLY WE HAVE -- WE ALSO 4777 02:46:22,040 --> 02:46:25,800 ARE LOOKING AT MANIA/HYPOMANIA 4778 02:46:25,800 --> 02:46:26,760 SCORES AND YOU CAN SEE 4779 02:46:26,760 --> 02:46:28,640 REDUCTIONS ON THE RIGHT AS WELL 4780 02:46:28,640 --> 02:46:30,360 OVER TIME IN THOSE SCORES. 4781 02:46:30,360 --> 02:46:33,000 IN ALL FOUR OF THE CATEGORIES 4782 02:46:33,000 --> 02:46:37,080 THAT WE WERE LOOKING AT, WE TEAD 4783 02:46:37,080 --> 02:46:38,600 OF THE INCREASES YOU WERE SEEING 4784 02:46:38,600 --> 02:46:39,920 IN THE REST OF THE POPULATION WE 4785 02:46:39,920 --> 02:46:41,800 ACTUALLY SAW SIGNIFICANT 4786 02:46:41,800 --> 02:46:44,240 DEYEASTS, AND 4787 02:46:44,240 --> 02:46:45,160 DECREASES AND PEOPLE HAD 4788 02:46:45,160 --> 02:46:46,480 BASICALLY HALF THE ODDS OF STILL 4789 02:46:46,480 --> 02:46:49,200 BEING IN TIER TWO OR THREE AFTER 4790 02:46:49,200 --> 02:46:51,000 A THREE TO SIX-MONTH FOLLOW-UP. 4791 02:46:51,000 --> 02:46:54,680 SO WE DID SEE A LOT OF PEOPLE 4792 02:46:54,680 --> 02:46:56,600 COMING DOWN IN TIER BECAUSE OF 4793 02:46:56,600 --> 02:46:58,400 THE INTERVENTION. 4794 02:46:58,400 --> 02:46:58,840 NEXT SLIDE. 4795 02:46:58,840 --> 02:47:01,040 I JUST WANT TO SHOW THAT AS I 4796 02:47:01,040 --> 02:47:04,640 SAID, WE HAD A REAL BACKUP IN 4797 02:47:04,640 --> 02:47:06,080 OUR INDIVIDUAL THERAPY AND 4798 02:47:06,080 --> 02:47:08,160 INDIVIDUAL TREATMENT IN OUR 4799 02:47:08,160 --> 02:47:13,400 SYSTEM, AND SO ONE OF THE 4800 02:47:13,400 --> 02:47:16,160 THINGS WE LOOKED AT IS WHERE ARE 4801 02:47:16,160 --> 02:47:17,000 THE REFERRALS GOING TO OUR 4802 02:47:17,000 --> 02:47:20,400 PROGRAM, AND WE ACTUALLY FOUND 4803 02:47:20,400 --> 02:47:21,760 THAT MORE THAN MORE THAN HALF 4804 02:47:21,760 --> 02:47:24,040 WENT TO GROUP-BASED PROGRAMS, 4805 02:47:24,040 --> 02:47:26,200 WHICH WAS A REALLY GOOD FINDING 4806 02:47:26,200 --> 02:47:29,640 FOR US FROM A FEASIBILITY 4807 02:47:29,640 --> 02:47:30,840 STANDPOINT AND BEING ABLE TO 4808 02:47:30,840 --> 02:47:33,120 DEAL WITH THE MASSIVE MENTAL 4809 02:47:33,120 --> 02:47:35,760 HEALTH NEEDS OF OUR SYSTEM AND 4810 02:47:35,760 --> 02:47:40,480 ACTUALLY ONLY 8% OF THE 4811 02:47:40,480 --> 02:47:48,000 95 PEOPLE ACTUALLY NEEDED THAT 4812 02:47:48,000 --> 02:47:49,120 THERAPY, SO THIS PROGRAM IS 4813 02:47:49,120 --> 02:47:50,320 REALLY HELPING US TO BE ABLE TO 4814 02:47:50,320 --> 02:47:51,400 GET SOME TREATMENT AND 4815 02:47:51,400 --> 02:47:52,680 OPPORTUNITIES TO PEOPLE TO TAKE 4816 02:47:52,680 --> 02:47:55,560 CARE OF THEMSELVES. 4817 02:47:55,560 --> 02:47:58,000 AND NOT OVERBURDENING THE MENTAL 4818 02:47:58,000 --> 02:48:03,600 HEALTH SYSTEM. 4819 02:48:03,600 --> 02:48:05,640 THIS IS OUR CURRENT RESILIENCE 4820 02:48:05,640 --> 02:48:06,440 STUDY. 4821 02:48:06,440 --> 02:48:09,800 WE ARE ALMOST AT OUR GOAL OF 120 4822 02:48:09,800 --> 02:48:11,680 PEEP 120 4823 02:48:11,680 --> 02:48:12,480 PEOPLE ENROLLED. 4824 02:48:12,480 --> 02:48:14,440 WE HAVE 104 RIGHT NOW AND WE 4825 02:48:14,440 --> 02:48:16,400 HOPE TO FINISH WITHIN SEVERAL 4826 02:48:16,400 --> 02:48:17,400 MONTHS OF ENROLLMENT. 4827 02:48:17,400 --> 02:48:18,520 I THINK JUST GIVEN TIME, I'M 4828 02:48:18,520 --> 02:48:20,520 GOING TO KEEP GOING BUT WE HAVE 4829 02:48:20,520 --> 02:48:22,960 ONE TO TWO MORE COHORTS OR 4830 02:48:22,960 --> 02:48:23,200 GROUPS. 4831 02:48:23,200 --> 02:48:24,520 I WANT TO SAY THANK YOU, IT 4832 02:48:24,520 --> 02:48:25,720 REALLY DID TAKE AN ENTIRE TEAM 4833 02:48:25,720 --> 02:48:27,160 TO BE ABLE TO DO A PROJECT LIKE 4834 02:48:27,160 --> 02:48:28,360 THIS AT THE POPULATION LEVEL, 4835 02:48:28,360 --> 02:48:32,040 AND TO BE ABLE TO WORK WITH NOW 4836 02:48:32,040 --> 02:48:32,800 MORE THAN 100,000 PATIENTS 4837 02:48:32,800 --> 02:48:35,200 INVOLVED IN THE POPULATION 4838 02:48:35,200 --> 02:48:35,760 MENTAL WELLNESS PROGRAM. 4839 02:48:35,760 --> 02:48:37,440 SO I WANT TO THANK EVERYBODY FOR 4840 02:48:37,440 --> 02:48:38,440 THEIR EFFORTS, AND I WANT TO 4841 02:48:38,440 --> 02:48:40,040 THANK YOU ALL FOR INVITING ME TO 4842 02:48:40,040 --> 02:48:44,680 SHARE OUR WORK WITH YOU. 4843 02:48:44,680 --> 02:48:45,480 >> GREAT. 4844 02:48:45,480 --> 02:48:46,520 THROUGH SO MUCH, ZEV. 4845 02:48:46,520 --> 02:48:47,640 THAT'S JUST AN INCREDIBLE AMOUNT 4846 02:48:47,640 --> 02:48:48,160 OF WORK. 4847 02:48:48,160 --> 02:48:49,800 AND LIKE YOU SAID, TO LAUNCH 4848 02:48:49,800 --> 02:48:51,000 THAT IN SEVEN DAYS AND GET THAT 4849 02:48:51,000 --> 02:48:52,960 UP AND MOVING FOR SUPPORT IS 4850 02:48:52,960 --> 02:48:56,360 JUST AN AMAZING -- I'M ALREADY 4851 02:48:56,360 --> 02:48:57,240 STARTING TO SEE QUESTIONS COME 4852 02:48:57,240 --> 02:48:59,960 THROUGH IN THE CHAT. 4853 02:48:59,960 --> 02:49:01,080 I ENCOURAGE THAT TO KEEP GOING. 4854 02:49:01,080 --> 02:49:02,360 I'LL TURN IT OVER TO OUR LAST 4855 02:49:02,360 --> 02:49:03,400 SPEAKER AND THEN WE'LL OPEN IT 4856 02:49:03,400 --> 02:49:04,440 UP FOR DISCUSSION. 4857 02:49:04,440 --> 02:49:10,400 SO OUR NEXT SPEAKER IS DR. JUDY 4858 02:49:10,400 --> 02:49:12,680 MOSKOWITZ AND SHE'S GOING TO 4859 02:49:12,680 --> 02:49:16,240 TELL US ABOUT THE FOREST STUDY. 4860 02:49:16,240 --> 02:49:16,680 >> GREAT. 4861 02:49:16,680 --> 02:49:17,880 THANK YOU. 4862 02:49:17,880 --> 02:49:19,800 YES, SO THANK YOU FOR HAVING ME. 4863 02:49:19,800 --> 02:49:22,760 I'M HAPPY DOING HERE TO TALK 4864 02:49:22,760 --> 02:49:25,160 ABOUT FOREST, WHICH IS NOT ABOUT 4865 02:49:25,160 --> 02:49:28,680 NATURE BATHING OR PLANT 4866 02:49:28,680 --> 02:49:29,000 COMMUNICATION. 4867 02:49:29,000 --> 02:49:31,920 IT'S A FUNCTION OF -- WE NAME 4868 02:49:31,920 --> 02:49:33,720 MOST OF OUR STUDIES USING SORT 4869 02:49:33,720 --> 02:49:36,680 OF BOTANICAL OR PLANT OR FLOWER 4870 02:49:36,680 --> 02:49:37,320 ACRONYMS. 4871 02:49:37,320 --> 02:49:39,800 SO FOREST ACTUALLY STANDS FOR 4872 02:49:39,800 --> 02:49:40,920 FOSTERING OPTIMAL REGULATION OF 4873 02:49:40,920 --> 02:49:42,480 EMOTION TO PREVENT SECONDARY 4874 02:49:42,480 --> 02:49:48,480 TRAUMA. 4875 02:49:48,480 --> 02:49:49,800 SO OUR PROGRAM OF RESEARCH HAS 4876 02:49:49,800 --> 02:49:54,520 REALLY CENTERED ON THIS 4877 02:49:54,520 --> 02:49:55,160 MULTICOMPONENT INTERVENTION THAT 4878 02:49:55,160 --> 02:49:57,720 TEACHES PEOPLE HOW TO HAVE MORE 4879 02:49:57,720 --> 02:49:59,000 POSITIVE EMOTION ON A DAILY 4880 02:49:59,000 --> 02:50:00,560 BASIS TO COPE WITH WHATEVER TYPE 4881 02:50:00,560 --> 02:50:02,640 OF STRESS THEY'RE COPING WITH. 4882 02:50:02,640 --> 02:50:06,480 SO WE'VE DONE A NUMBER OF TRIALS 4883 02:50:06,480 --> 02:50:10,280 IN MOSTLY PEOPLE COPING WITH 4884 02:50:10,280 --> 02:50:11,400 HEALTH-RELATED STRESS, HIGH 4885 02:50:11,400 --> 02:50:14,440 SCHOOL STUDENTS, SO -- SORT OF 4886 02:50:14,440 --> 02:50:17,200 RUN THE GAMUT IN SEEING WHETHER 4887 02:50:17,200 --> 02:50:19,240 WE CAN -- WHEN WE TEACH PEOPLE 4888 02:50:19,240 --> 02:50:21,640 THESE SKILLS, IF THEY HAVE 4889 02:50:21,640 --> 02:50:25,680 IMPROVEMENTS AND TR THEIR 4890 02:50:25,680 --> 02:50:26,280 PSYCHOLOGICAL WELL-BEING AS A 4891 02:50:26,280 --> 02:50:27,680 RESULT. 4892 02:50:27,680 --> 02:50:30,320 SO AROUND THE END OF 2019, I 4893 02:50:30,320 --> 02:50:39,640 GUESS IT WAS SUMMER OF 2019, WE 4894 02:50:39,640 --> 02:50:41,560 COULD HAVE CONTINUED WITH 4895 02:50:41,560 --> 02:50:42,480 RANDOMIZED TRIAL AFTER 4896 02:50:42,480 --> 02:50:43,680 RANDOMIZED TRIAL, EFFICACY 4897 02:50:43,680 --> 02:50:44,720 TRIAL, EFFECTIVENESS TRIAL. 4898 02:50:44,720 --> 02:50:46,960 BUT WE WERE REALLY STARTING TO 4899 02:50:46,960 --> 02:50:48,280 THINK HOW COULD WE -- WE'VE GOT 4900 02:50:48,280 --> 02:50:51,360 GOOD EVIDENCE THAT THIS WORKS. 4901 02:50:51,360 --> 02:50:52,640 FOR THE PEOPLE WHO DO IT. 4902 02:50:52,640 --> 02:50:54,520 SO HOW CAN WE HAVE MORE OF AN 4903 02:50:54,520 --> 02:50:57,040 IMPACT WITH THIS WORK? 4904 02:50:57,040 --> 02:51:00,640 AND IN AUGUST OF 2019, I WAS AT 4905 02:51:00,640 --> 02:51:01,160 THE AMERICAN PSYCHOLOGICAL 4906 02:51:01,160 --> 02:51:02,920 ASSOCIATION CONFERENCE IN 4907 02:51:02,920 --> 02:51:04,000 CHICAGO, AND WATCHING ONE OF 4908 02:51:04,000 --> 02:51:05,720 THEIR MAIN STAGE EVENTS. 4909 02:51:05,720 --> 02:51:08,280 IT WAS ON GUN VIOLENCE. 4910 02:51:08,280 --> 02:51:10,560 AND ONE OF THE SPEAKERS WAS 4911 02:51:10,560 --> 02:51:13,160 EDDIE BOCANEGRA, WHO AT THE TIME 4912 02:51:13,160 --> 02:51:14,600 WAS THE SENIOR DIRECTOR FOR A 4913 02:51:14,600 --> 02:51:16,920 PROGRAM CALLED READY CHICAGO. 4914 02:51:16,920 --> 02:51:19,760 WHICH IS A GUN VIOLENCE 4915 02:51:19,760 --> 02:51:24,600 PREVENTION AND INTERVENTION 4916 02:51:24,600 --> 02:51:27,320 PROGRAM WHERE THEY REACH OUT TO 4917 02:51:27,320 --> 02:51:29,280 MEN AT HIGHEST RISK OF BEING 4918 02:51:29,280 --> 02:51:31,680 INVOLVED IN GUN VIOLENCE AND 4919 02:51:31,680 --> 02:51:33,240 BRING THEM IN FOR A 12-MONTH 4920 02:51:33,240 --> 02:51:35,280 PROGRAM OF COGNITIVE BEHAVIORAL 4921 02:51:35,280 --> 02:51:36,560 SKILLS, JOB TRAINING, 4922 02:51:36,560 --> 02:51:37,720 TRANSITIONAL SKILLS, OTHER SORT 4923 02:51:37,720 --> 02:51:39,800 OF WRAP-AROUND SERVICES. 4924 02:51:39,800 --> 02:51:42,400 SO I SAW EDDIE SPEAK AND HAD THE 4925 02:51:42,400 --> 02:51:45,480 OPPORTUNITY TO MEET HIM BACK 4926 02:51:45,480 --> 02:51:47,040 STAGE, AND I WAS -- YOU KNOW, 4927 02:51:47,040 --> 02:51:47,920 THAT POINT I WASN'T THINKING 4928 02:51:47,920 --> 02:51:48,440 ABOUT OUR PROGRAM. 4929 02:51:48,440 --> 02:51:50,200 I WAS JUST -- I'M A 4930 02:51:50,200 --> 02:51:51,200 PSYCHOLOGIST, I REALLY THINK 4931 02:51:51,200 --> 02:51:53,240 WHAT YOU'RE DOING IS AMAZING, 4932 02:51:53,240 --> 02:51:54,240 HOW CAN I HELP? 4933 02:51:54,240 --> 02:51:55,560 I'M HERE IN CHICAGO. 4934 02:51:55,560 --> 02:51:57,960 AND HIS FIRST THOUGHT WAS, WELL, 4935 02:51:57,960 --> 02:51:59,760 WE'RE DOING THESE COGNITIVE 4936 02:51:59,760 --> 02:52:02,240 BEHAVIORAL SKILLS, WE COULD USE 4937 02:52:02,240 --> 02:52:03,560 A PSYCHOLOGIST TO HELP US WITH 4938 02:52:03,560 --> 02:52:04,680 FIDELITY TO THOSE SKILLS. 4939 02:52:04,680 --> 02:52:06,080 I WAS LIKE, OH, I'M NOT THAT 4940 02:52:06,080 --> 02:52:06,880 KIND OF PSYCHOLOGIST. 4941 02:52:06,880 --> 02:52:07,720 BECAUSE I'M A SOCIAL 4942 02:52:07,720 --> 02:52:08,240 PSYCHOLOGIST. 4943 02:52:08,240 --> 02:52:10,000 SO I WAS LIKE, BUT I KNOW 4944 02:52:10,000 --> 02:52:11,240 PEOPLE, I COULD PROBABLY FIND 4945 02:52:11,240 --> 02:52:13,520 SOMEONE TO HELP YOU WITH THIS. 4946 02:52:13,520 --> 02:52:15,520 AND THEN HE SAID WHAT DO YOU DO? 4947 02:52:15,520 --> 02:52:18,160 AND I WAS LIKE, WELL, I DO THIS 4948 02:52:18,160 --> 02:52:19,120 POSITIVE EMOTION THING TO HELP 4949 02:52:19,120 --> 02:52:20,520 PEOPLE COPE WITH STRESS. 4950 02:52:20,520 --> 02:52:21,760 AND I PROBABLY SAID IT JUST LIKE 4951 02:52:21,760 --> 02:52:24,000 THAT TOO, BECAUSE I'M ALWAYS 4952 02:52:24,000 --> 02:52:25,880 VERY WARY OF COMING OFF AS, UR 4953 02:52:25,880 --> 02:52:28,080 KNOW, JUST BE HAPPY AND IT WILL 4954 02:52:28,080 --> 02:52:29,480 FIX EVERYTHING NO MATTER HOW 4955 02:52:29,480 --> 02:52:33,760 SEVERE YOUR STRESS IS. 4956 02:52:33,760 --> 02:52:35,960 BUT AS SOON AS I DESCRIBED TO 4957 02:52:35,960 --> 02:52:37,160 HIM A LITTLE BIT, HE IMMEDIATELY 4958 02:52:37,160 --> 02:52:38,240 SAID, CAN YOU HELP OUR STAFF? 4959 02:52:38,240 --> 02:52:41,520 THIS IS REALLY CHALLENGING WORK, 4960 02:52:41,520 --> 02:52:46,800 THERE'S HIGH RATES OF BURNOUT, 4961 02:52:46,800 --> 02:52:47,920 SECONDARY TRAUMA, REALLY HIGH 4962 02:52:47,920 --> 02:52:49,200 TURNOVER. 4963 02:52:49,200 --> 02:52:50,400 COULD THIS PROGRAM POSSIBLY HELP 4964 02:52:50,400 --> 02:52:51,600 OUR STAFF COPE BETTER WITH THE 4965 02:52:51,600 --> 02:52:53,800 STRESS OF BEING A FRONT LINE GUN 4966 02:52:53,800 --> 02:53:00,600 VIOLENCE PREVENTION WORKER? 4967 02:53:00,600 --> 02:53:04,120 SO WITH MY COLLEAGUES, WE 4968 02:53:04,120 --> 02:53:08,680 STARTED TALKING WITH -- AT THE 4969 02:53:08,680 --> 02:53:10,360 DIFFERENT SITES OF READY. 4970 02:53:10,360 --> 02:53:11,120 READY HAS THREE SITES LOCATED IN 4971 02:53:11,120 --> 02:53:15,280 SORT OF THE SOUTH AND WEST SIDE 4972 02:53:15,280 --> 02:53:15,720 OF CHICAGO. 4973 02:53:15,720 --> 02:53:17,120 SO WE WENT TO SOME OF THEIR 4974 02:53:17,120 --> 02:53:18,320 MEETINGS, WE PRESENTED SORT OF 4975 02:53:18,320 --> 02:53:21,400 AN OVERVIEW OF THE PROGRAM, HAD 4976 02:53:21,400 --> 02:53:23,520 THEM PRACTICE SOME OF THE 4977 02:53:23,520 --> 02:53:28,680 SKILLS, JUST IN SORT OF A GROUP 4978 02:53:28,680 --> 02:53:30,800 FORMAT, AND ASKED PEOPLE WHO WAS 4979 02:53:30,800 --> 02:53:31,800 INTERESTED IN LEARNING MORE 4980 02:53:31,800 --> 02:53:41,520 ABOUT THIS PROGRAM. 4981 02:53:41,520 --> 02:53:44,680 SO WE WERE ABLE TO GET SOME -- A 4982 02:53:44,680 --> 02:53:46,040 SMALL POT OF MONEY TO RUN A 4983 02:53:46,040 --> 02:53:47,360 PILOT TEST OF THE PROGRAM WHERE 4984 02:53:47,360 --> 02:53:49,440 WE DO SORT OF A TRAIN THE 4985 02:53:49,440 --> 02:53:49,720 TRAINERS. 4986 02:53:49,720 --> 02:53:50,880 BECAUSE THAT WAS OUR FIRST 4987 02:53:50,880 --> 02:53:51,920 THOUGHT OF A WAY FOR US TO BE 4988 02:53:51,920 --> 02:53:54,920 ABLE TO IMPLEMENT THIS PROGRAM 4989 02:53:54,920 --> 02:53:58,200 ACROSS THE REA DI SITES. 4990 02:53:58,200 --> 02:54:02,240 SO WE CALLED IT PEAs, WHICH IS 4991 02:54:02,240 --> 02:54:04,440 SORT OF A PLANT, FOR POSITIVE 4992 02:54:04,440 --> 02:54:11,560 EMOTION AMBASSADORS. 4993 02:54:11,560 --> 02:54:13,520 WE WORKED WITH ABOUT 15 STAFF 4994 02:54:13,520 --> 02:54:16,480 MEMBERS FROM ACROSS THE THREE 4995 02:54:16,480 --> 02:54:19,520 READI SITES AND WENT THROUGH THE 4996 02:54:19,520 --> 02:54:26,480 PROGRAM WEEK BY WEEK. 4997 02:54:26,480 --> 02:54:27,880 SO WE GROUPED THE SKILLS INTO 4998 02:54:27,880 --> 02:54:29,440 FIVE WEEKS OF CONTENT AND A 4999 02:54:29,440 --> 02:54:31,720 SIXTH WEEK WE RAN SORT OF AS A 5000 02:54:31,720 --> 02:54:33,560 FOCUS GROUP TO GET FEEDBACK. 5001 02:54:33,560 --> 02:54:34,760 AND EACH SESSION, WE WOULD TEACH 5002 02:54:34,760 --> 02:54:38,800 A SKILL OR TWO AND THEN WE 5003 02:54:38,800 --> 02:54:39,680 WOULD -- THEN THEY WOULD 5004 02:54:39,680 --> 02:54:40,800 PRACTICE IT DURING THE WEEK, AND 5005 02:54:40,800 --> 02:54:43,960 WE WOULD ALSO TALK ABOUT ALONG 5006 02:54:43,960 --> 02:54:45,840 THE WAY HOW MIGHT THIS BE 5007 02:54:45,840 --> 02:54:49,960 IMPLEMENTED AT READI. 5008 02:54:49,960 --> 02:54:51,160 BECAUSE IT WAS PRETTY CLEAR TO 5009 02:54:51,160 --> 02:54:52,600 US WE WEREN'T JUST GOING TO GO 5010 02:54:52,600 --> 02:54:54,520 IN THERE, DO A PRESENTATION AND 5011 02:54:54,520 --> 02:54:56,320 SAY GO AHEAD, NOW YOU DO IT. 5012 02:54:56,320 --> 02:54:58,720 SO WE WALKED THEM THROUGH THE 5013 02:54:58,720 --> 02:54:58,960 SKILLS. 5014 02:54:58,960 --> 02:55:01,760 THIS WAS IN THE FALL OF 2020 SO 5015 02:55:01,760 --> 02:55:02,640 IT WAS ALL ON ZOOM. 5016 02:55:02,640 --> 02:55:04,200 A LOT OF THINGS GOING ON IN THE 5017 02:55:04,200 --> 02:55:10,400 WORLD AS WE'VE ALREADY DISCUSSED 5018 02:55:10,400 --> 02:55:11,880 DURING THE SIX WEEKS WE WERE 5019 02:55:11,880 --> 02:55:13,000 RUNNING THIS WITH THEM, THE 5020 02:55:13,000 --> 02:55:15,480 TRIAL FOR THE POLICE WHO SHOT 5021 02:55:15,480 --> 02:55:16,840 BREONNA TAYLOR, THE VERDICT CAME 5022 02:55:16,840 --> 02:55:17,360 DOWN FOR THAT. 5023 02:55:17,360 --> 02:55:23,840 SO WE HAD A LOT OF SORT OF 5024 02:55:23,840 --> 02:55:25,000 PROCESSING OF THAT AS PART OF 5025 02:55:25,000 --> 02:55:25,760 THE CLASS BECAUSE YOU CAN'T JUST 5026 02:55:25,760 --> 02:55:27,080 TALK ABOUT POSITIVE EMOTION, WE 5027 02:55:27,080 --> 02:55:28,160 HAVE TO TALK ABOUT THE STRESS 5028 02:55:28,160 --> 02:55:29,280 AND THE NEGATIVE EMOTIONS THAT 5029 02:55:29,280 --> 02:55:35,960 ARE GOING ON AS WELL. 5030 02:55:35,960 --> 02:55:38,240 SO WE GOT SOME REALLY GREAT 5031 02:55:38,240 --> 02:55:41,200 FEEDBACK TO THAT PROGRAM AND TO 5032 02:55:41,200 --> 02:55:42,840 THE SKILLS, AND HERE ARE TWO OF 5033 02:55:42,840 --> 02:55:44,680 MY FAVORITES. 5034 02:55:44,680 --> 02:55:46,440 THE FIRST ONE, I THINK FOR STAFF 5035 02:55:46,440 --> 02:55:47,880 IT'S ABSOLUTELY NECESSARY AND 5036 02:55:47,880 --> 02:55:49,120 IMPORTANT BECAUSE YOU CAN HAVE 5037 02:55:49,120 --> 02:55:49,720 BURNOUT. 5038 02:55:49,720 --> 02:55:50,640 YOU'RE DEALING WITH NOT JUST THE 5039 02:55:50,640 --> 02:55:52,920 EMOTIONS OF YOURSELF, BUT OF AN 5040 02:55:52,920 --> 02:55:53,920 ENTIRE GROUP OF OTHER PEOPLE 5041 02:55:53,920 --> 02:55:55,040 THAT HAVE A LOT OF THINGS GOING 5042 02:55:55,040 --> 02:55:56,080 ON WITH THEM. 5043 02:55:56,080 --> 02:55:57,760 AND YOU HAVE TO TACKLE THAT ON A 5044 02:55:57,760 --> 02:56:00,440 CONSISTENT BASIS. 5045 02:56:00,440 --> 02:56:08,840 PEAs, AGAIN IS FLES SAIR . 5046 02:56:08,840 --> 02:56:10,960 THE QUOTE ON THE RIGHT, WE LIKED 5047 02:56:10,960 --> 02:56:12,240 IT SO MUCH, WE PUT IT ON THE 5048 02:56:12,240 --> 02:56:13,560 BACK OF THE JOURNALS WE GAVE 5049 02:56:13,560 --> 02:56:14,560 THEM AS A THANK YOU FOR 5050 02:56:14,560 --> 02:56:15,720 PARTICIPATING IN THE GROUP. 5051 02:56:15,720 --> 02:56:16,960 ONE OF THE PARTICIPANTS SAID, 5052 02:56:16,960 --> 02:56:18,800 THE USE OF POSITIVE EMOTIONS, IT 5053 02:56:18,800 --> 02:56:19,920 FEELS ALMOST LIKE GOING OUTSIDE 5054 02:56:19,920 --> 02:56:20,640 WITH A RAINCOAT. 5055 02:56:20,640 --> 02:56:22,160 IF YOU GO OUT WITH A SWEATER, 5056 02:56:22,160 --> 02:56:24,400 YOU GET RAINED ON AND YOUR SHIRT 5057 02:56:24,400 --> 02:56:25,480 GETS HEAVY, YOU HAVE TO CARRY 5058 02:56:25,480 --> 02:56:26,800 THAT BURDEN. 5059 02:56:26,800 --> 02:56:28,320 THE RAINCOAT ALLOWS THAT STUFF 5060 02:56:28,320 --> 02:56:29,760 TO WASH OFF OF YOU. 5061 02:56:29,760 --> 02:56:30,880 OFTENTIMES AT READI, WE'RE 5062 02:56:30,880 --> 02:56:32,160 STANDING IN THE RAIN ALL THE 5063 02:56:32,160 --> 02:56:32,640 TIME. 5064 02:56:32,640 --> 02:56:33,840 I FEEL LIKE WE'RE OFTEN THE 5065 02:56:33,840 --> 02:56:37,000 PEOPLE WHO NEED TO REMEMBER WHY 5066 02:56:37,000 --> 02:56:38,440 WE'RE HERE AND REMINDING US AND 5067 02:56:38,440 --> 02:56:39,960 GIVING US TOOLS TO NOT LET THOSE 5068 02:56:39,960 --> 02:56:44,680 THINGS WEIGH US DOWN. 5069 02:56:44,680 --> 02:56:46,960 SO WE WERE JUST WRAPPING UP THIS 5070 02:56:46,960 --> 02:56:49,040 GETTING FEEDBACK AND DOING SOME 5071 02:56:49,040 --> 02:56:50,800 FOLLOW-UP INTERVIEWS WITH THE 5072 02:56:50,800 --> 02:56:51,920 POSITIVE EMOTION AMBASSADORS 5073 02:56:51,920 --> 02:56:58,480 WHEN THIS CALL CAME OUT, THIS 5074 02:56:58,480 --> 02:57:01,320 R21 R33 FOR FIREARM INJURY AND 5075 02:57:01,320 --> 02:57:02,440 MORTALITY PREVENTION RESEARCH. 5076 02:57:02,440 --> 02:57:04,280 WORKING WITH READI CHICAGO, IS 5077 02:57:04,280 --> 02:57:06,080 NOT SOMETHING I WOULD HAVE EVEN 5078 02:57:06,080 --> 02:57:07,160 NOTICED BUT IT WAS REALLY CLEAR 5079 02:57:07,160 --> 02:57:08,400 TO US THAT THIS WAS A GREAT FIT 5080 02:57:08,400 --> 02:57:09,760 FOR THE WORK THAT WE WERE DOING 5081 02:57:09,760 --> 02:57:10,920 AND THAT WE WANTED TO CONTINUE 5082 02:57:10,920 --> 02:57:14,480 TO DO. 5083 02:57:14,480 --> 02:57:16,480 SO OUR GOAL FORM THIS WAS WE AIM 5084 02:57:16,480 --> 02:57:17,960 TO ADAPT, IMPLEMENT AND 5085 02:57:17,960 --> 02:57:19,160 MANUALIZE THE FOREST PROGRAM AND 5086 02:57:19,160 --> 02:57:21,800 BUILD CAPACITY FOR READI CHICAGO 5087 02:57:21,800 --> 02:57:23,680 TO SUSTAINABLY ENHANCE 5088 02:57:23,680 --> 02:57:25,560 RESILIENCE, PREVENT BURNOUT AND 5089 02:57:25,560 --> 02:57:27,200 REDUCE TURNOVER AMONG FRONT-LINE 5090 02:57:27,200 --> 02:57:29,920 STAFF WORKING TO PREVENT FIREARM 5091 02:57:29,920 --> 02:57:35,160 INJURY AND MORTALITY. 5092 02:57:35,160 --> 02:57:36,600 SO THIS IS A PHASED AWARD. 5093 02:57:36,600 --> 02:57:39,760 WE ARE ABOUT 8 MONTHS INTO THE 5094 02:57:39,760 --> 02:57:40,480 R21 PHASE, 8 MONTHS OF THE TWO 5095 02:57:40,480 --> 02:57:41,080 YEARS. 5096 02:57:41,080 --> 02:57:46,480 WHERE OUR GOALS ARE TO ADAPT AND 5097 02:57:46,480 --> 02:57:47,960 FINALIZE THE CONTENT OF THE 5098 02:57:47,960 --> 02:57:48,320 INTERVENTION. 5099 02:57:48,320 --> 02:57:49,960 SO WE DON'T REALLY ANTICIPATE 5100 02:57:49,960 --> 02:57:50,840 THAT THE CORE SKILLS ARE GOING 5101 02:57:50,840 --> 02:57:53,920 TO CHANGE A LOT. 5102 02:57:53,920 --> 02:57:55,560 WE DID HAVE FEEDBACK THAT THEY 5103 02:57:55,560 --> 02:57:58,520 WANTED TO BE MORE 5104 02:57:58,520 --> 02:57:59,600 TRAUMA-INFORMED AND WE ARE 5105 02:57:59,600 --> 02:58:02,200 INCORPORATING THAT PERSPECTIVE. 5106 02:58:02,200 --> 02:58:03,760 SOME OTHER SORT OF CULTURAL 5107 02:58:03,760 --> 02:58:06,080 TAILORING AND SOME OTHER NEEDED 5108 02:58:06,080 --> 02:58:07,280 ADAPTATIONS, AND WE'RE GOING TO 5109 02:58:07,280 --> 02:58:12,400 BE GETTING FEEDBACK THROUGH THIS 5110 02:58:12,400 --> 02:58:13,880 FIRST TWO YEARS ON WAYS WE CAN 5111 02:58:13,880 --> 02:58:18,440 IMPROVE THE CONTENT. 5112 02:58:18,440 --> 02:58:20,080 AND THEN WE'RE ALSO LOOKING TO 5113 02:58:20,080 --> 02:58:21,160 INFORM STRATEGIES TO IMPLEMENT 5114 02:58:21,160 --> 02:58:23,800 FOREST AT THE THREE READI SITES 5115 02:58:23,800 --> 02:58:25,240 BASED OP SYSTEM, ORGANIZATION 5116 02:58:25,240 --> 02:58:26,400 AND STAFF FACTORS. 5117 02:58:26,400 --> 02:58:31,680 SO OUR PLAN WAS TO DO SURVEYS, 5118 02:58:31,680 --> 02:58:32,640 REALLY IMPLEMENTATION SCIENCE 5119 02:58:32,640 --> 02:58:34,640 KIND OF SURVEYS LOOKING AT THESE 5120 02:58:34,640 --> 02:58:35,920 CONTEXTUAL FACTORS. 5121 02:58:35,920 --> 02:58:37,360 WITH THE STAFF, WITH LEADERSHIP 5122 02:58:37,360 --> 02:58:45,080 AND OTHER KEY STAKEHOLDERS, AND 5123 02:58:45,080 --> 02:58:45,920 THEN FOLLOWING THAT WE'RE GOING 5124 02:58:45,920 --> 02:58:47,520 TO DESIGN THE STUDY WE WANT TO 5125 02:58:47,520 --> 02:58:49,200 DO IN THE THREE-YEAR FOLLOW-UP 5126 02:58:49,200 --> 02:58:51,920 PHASE IF WE NEED OUR BENCHMARKS. 5127 02:58:51,920 --> 02:58:57,400 FOR THE FIRST TWO, INCLUDING HOW 5128 02:58:57,400 --> 02:59:00,160 ARE WE GOING TO EVALUATE IT. 5129 02:59:00,160 --> 02:59:01,680 AS A PSYCHOLOGIST, WE WANT TO 5130 02:59:01,680 --> 02:59:02,360 LOOK AT THE WELL-BEING OF THE 5131 02:59:02,360 --> 02:59:03,560 FRONT LINE WORKERS, WE WANT TO 5132 02:59:03,560 --> 02:59:05,960 LOOK AT THEIR LEVELS OF BURNOUT. 5133 02:59:05,960 --> 02:59:07,280 THE LEADERSHIP AT READI IS GOING 5134 02:59:07,280 --> 02:59:08,680 TO HAVE OTHER THINGS THAT THEY 5135 02:59:08,680 --> 02:59:09,600 MIGHT BE INTERESTED IN, IN 5136 02:59:09,600 --> 02:59:10,640 ADDITION TO JUST INDIVIDUAL 5137 02:59:10,640 --> 02:59:10,960 WELL-BEING. 5138 02:59:10,960 --> 02:59:13,840 SO WE'RE GOING TO DO SOME 5139 02:59:13,840 --> 02:59:15,880 INTERVIEWS WITH THOSE KEY 5140 02:59:15,880 --> 02:59:16,600 STAKEHOLDERS TO FIND OUT WHAT 5141 02:59:16,600 --> 02:59:18,080 THEY WOULD LIKE TO SEE OUT OF 5142 02:59:18,080 --> 02:59:19,720 THIS PROGRAM AND HOW WE CAN BEST 5143 02:59:19,720 --> 02:59:24,120 EVALUATE IT. 5144 02:59:24,120 --> 02:59:27,720 AND THEN IN THE R33 PHASE, IF 5145 02:59:27,720 --> 02:59:29,720 WE'RE -- IF WE DO A GOOD JOB IN 5146 02:59:29,720 --> 02:59:31,200 THE FIRST PART AND WE GET THIS 5147 02:59:31,200 --> 02:59:33,080 SECOND PHASE, WE WILL DO A 5148 02:59:33,080 --> 02:59:34,280 LONGITUDINAL STUDY WHERE WE 5149 02:59:34,280 --> 02:59:35,200 IMPLEMENT THE PROGRAM AT READI, 5150 02:59:35,200 --> 02:59:37,040 AND THEN WE WANT TO TRY TO 5151 02:59:37,040 --> 02:59:38,800 FIGURE OUT HOW WE CAN MAKE IT 5152 02:59:38,800 --> 02:59:41,200 SUSTAINABLE, HOW WE CAN BUILD 5153 02:59:41,200 --> 02:59:42,320 READI CAPACITY SO THEY CAN 5154 02:59:42,320 --> 02:59:43,960 CONTINUE WITH IT ONCE THE 5155 02:59:43,960 --> 02:59:45,920 RESEARCHERS PULL OUT. 5156 02:59:45,920 --> 02:59:47,440 AND THEN POSSIBLY TO DISSEMINATE 5157 02:59:47,440 --> 02:59:49,640 TO OTHER GUN VIOLENCE PREVENTION 5158 02:59:49,640 --> 02:59:51,400 PROGRAMS IN CHICAGO AND OTHER 5159 02:59:51,400 --> 02:59:56,640 LARGE CITIES. 5160 02:59:56,640 --> 02:59:59,080 SO WHEN WE RECEIVED OUR FUNDING, 5161 02:59:59,080 --> 03:00:00,520 THE NORTHWESTERN COMMUNICATIONS 5162 03:00:00,520 --> 03:00:02,440 OFFICE GOT A CALL FROM SENATOR 5163 03:00:02,440 --> 03:00:04,960 DICK DURBIN, FROM HIS TEAM, AND 5164 03:00:04,960 --> 03:00:08,560 THEY WANTED TO -- AND SENATOR 5165 03:00:08,560 --> 03:00:09,440 DURBIN WAS VERY EXCITED ABOUT 5166 03:00:09,440 --> 03:00:11,000 THIS, BECAUSE HE'S BEEN A LONG 5167 03:00:11,000 --> 03:00:12,200 TIME ADVOCATE FOR INCREASING 5168 03:00:12,200 --> 03:00:14,680 FUNDING FOR GUN VIOLENCE 5169 03:00:14,680 --> 03:00:15,000 RESEARCH. 5170 03:00:15,000 --> 03:00:16,640 SO HE WAS VERY EXCITED THAT 5171 03:00:16,640 --> 03:00:18,320 NORTHWESTERN AND ACTUALLY THE 5172 03:00:18,320 --> 03:00:19,200 UNIVERSITY OF CHICAGO BOTH 5173 03:00:19,200 --> 03:00:21,640 RECEIVED A GRANT AT THE SAME 5174 03:00:21,640 --> 03:00:24,000 TIME TO WORK WITH READI CHICAGO 5175 03:00:24,000 --> 03:00:25,200 IN DIFFERENT CAPACITIES. 5176 03:00:25,200 --> 03:00:28,800 SO HERE WE ARE IN OUR PRESS 5177 03:00:28,800 --> 03:00:30,000 CONFERENCE WITH SENATOR DURBIN. 5178 03:00:30,000 --> 03:00:35,720 SO IT WAS KIND OF EXCITING. 5179 03:00:35,720 --> 03:00:39,760 SO THIS IS A TRUE PARTNERSHIP 5180 03:00:39,760 --> 03:00:41,160 BETWEEN THE RESEARCHERS AT 5181 03:00:41,160 --> 03:00:42,040 NORTHWESTERN AND THE READI 5182 03:00:42,040 --> 03:00:42,800 CHICAGO TEAM. 5183 03:00:42,800 --> 03:00:45,000 WE MEET WEEKLY TO TALK THROUGH 5184 03:00:45,000 --> 03:00:46,760 VARIOUS ASPECTS OF THE PROGRAM 5185 03:00:46,760 --> 03:00:48,320 AND TO UNDERSTAND WHAT WE'RE 5186 03:00:48,320 --> 03:00:54,440 SEEING IN THE DATA. 5187 03:00:54,440 --> 03:00:57,480 SO I'LL JUST GIVE YOU A LITTLE 5188 03:00:57,480 --> 03:00:58,600 INSIGHT, WE'RE EIGHT MONTHS IN 5189 03:00:58,600 --> 03:01:00,320 SO WE'VE JUST COMPLETED THIS 5190 03:01:00,320 --> 03:01:02,000 FIRST ROUND OF FOCUS GROUPS. 5191 03:01:02,000 --> 03:01:06,920 INITIALLY WE PLANNED ON DOING 5192 03:01:06,920 --> 03:01:07,680 SURVEYS, BUT IT WAS REALLY CLEAR 5193 03:01:07,680 --> 03:01:11,760 TO US AS WE LOOKED AT SOME OF 5194 03:01:11,760 --> 03:01:13,240 THE IMPLEMENTATION SCIENCE 5195 03:01:13,240 --> 03:01:14,440 SURVEYS THAT WE NEEDED TO OPEN 5196 03:01:14,440 --> 03:01:19,400 IT UP MORE AND REALLY LOOK MORE 5197 03:01:19,400 --> 03:01:20,520 BROADLY AND DO THESE FOCUS 5198 03:01:20,520 --> 03:01:23,440 GROUPS TO REALLY LOOK AT SORT OF 5199 03:01:23,440 --> 03:01:25,080 THINGS LIKE WHAT WORKS IN NEW 5200 03:01:25,080 --> 03:01:26,280 PROGRAMS THAT ARE ROLLED OUT, 5201 03:01:26,280 --> 03:01:32,520 WHAT DOESN'T WORK, WHAT SHOULD 5202 03:01:32,520 --> 03:01:33,840 WE AVOID DOING, WHAT WE MIGHT 5203 03:01:33,840 --> 03:01:39,400 WANT TO DO, AND TO GET VIEWS OF 5204 03:01:39,400 --> 03:01:41,080 WELLNESS AND HOW READI COULD 5205 03:01:41,080 --> 03:01:41,960 SUPPORT WELLNESS THROUGH THIS 5206 03:01:41,960 --> 03:01:42,360 PROGRAM. 5207 03:01:42,360 --> 03:01:44,680 SO WE DID FIVE FOCUS GROUPS. 5208 03:01:44,680 --> 03:01:46,720 TWO WITH OUTREACH WORKERS, ONE 5209 03:01:46,720 --> 03:01:48,520 WITH CREW CHIEFS, ONE WITH 5210 03:01:48,520 --> 03:01:49,720 COACHES AND MANAGERS SO TO GET A 5211 03:01:49,720 --> 03:01:51,680 RANGE OF ROLES AND GET THEIR 5212 03:01:51,680 --> 03:01:53,440 INPUT, AND THE GROUPS WERE VERY 5213 03:01:53,440 --> 03:01:54,200 DIFFERENT IN THE KINDS OF THINGS 5214 03:01:54,200 --> 03:02:01,200 THAT THEY WERE TELLING US. 5215 03:02:01,200 --> 03:02:03,240 SO WE'RE GOING TO AN OPEN CODING 5216 03:02:03,240 --> 03:02:05,480 PROCESS, THIS IS REALLY MESSY. 5217 03:02:05,480 --> 03:02:07,000 SO BE GENTLE ON ME. 5218 03:02:07,000 --> 03:02:08,200 WE'RE NOT THERE YET FIGURING 5219 03:02:08,200 --> 03:02:09,480 EVERYTHING WE HAVE, BUT I WANTED 5220 03:02:09,480 --> 03:02:10,680 TO GIVE YOU SOME INSIGHT INTO 5221 03:02:10,680 --> 03:02:11,480 WHAT WE'RE SEEING. 5222 03:02:11,480 --> 03:02:14,000 SO GENERALLY, FACILITATORS, 5223 03:02:14,000 --> 03:02:15,200 BARRIERS, SOME CONTEXTUAL 5224 03:02:15,200 --> 03:02:16,720 THINGS, AND THEN WE'RE ALSO 5225 03:02:16,720 --> 03:02:20,720 COLLECTING SUGGESTIONS FOR 5226 03:02:20,720 --> 03:02:23,160 IMPLEMENTATION. 5227 03:02:23,160 --> 03:02:24,600 SO IN TERMS OF FACILITATORS, 5228 03:02:24,600 --> 03:02:26,000 THERE ARE A LOT OF THINGS ABOUT 5229 03:02:26,000 --> 03:02:28,320 THE CULTURE OF READI THAT REALLY 5230 03:02:28,320 --> 03:02:30,200 MAKES IT READY TO HAVE A PROGRAM 5231 03:02:30,200 --> 03:02:30,840 LIKE THIS. 5232 03:02:30,840 --> 03:02:32,600 SO THEY REALLY HAVE AN 5233 03:02:32,600 --> 03:02:33,440 ACCEPTANCE OF NEGATIVE EMOTIONS 5234 03:02:33,440 --> 03:02:35,120 AND THE STRESS OF THE PROGRAM, 5235 03:02:35,120 --> 03:02:39,480 SO THEY ARE VERY MUCH IN LINE 5236 03:02:39,480 --> 03:02:40,120 WITH OUR POINT ABOUT OUR PROGRAM 5237 03:02:40,120 --> 03:02:41,480 IS NOT ABOUT IGNORING THE STRESS 5238 03:02:41,480 --> 03:02:43,200 OR PRETENDING LIKE NEGATIVE 5239 03:02:43,200 --> 03:02:44,120 EMOTIONS DON'T EXIST. 5240 03:02:44,120 --> 03:02:46,600 SO THEY ARE VERY GOOD AT BEING 5241 03:02:46,600 --> 03:02:48,560 AWARE OF NEGATIVE EMOTIONS. 5242 03:02:48,560 --> 03:02:50,200 AND THEIR CULTURE REALLY 5243 03:02:50,200 --> 03:02:57,680 SUPPORTS WELLNESS AND SELF-CARE. 5244 03:02:57,680 --> 03:02:58,240 I'LL GIVE YOU AN EXAMPLE. 5245 03:02:58,240 --> 03:03:00,520 SO AS AN EXAMPLE, THE CULTURE 5246 03:03:00,520 --> 03:03:01,600 SUPPORT, READI WANTS YOU TO BE 5247 03:03:01,600 --> 03:03:02,720 AT YOUR BEST IN ORDER TO GIVE 5248 03:03:02,720 --> 03:03:03,400 YOUR BEST. 5249 03:03:03,400 --> 03:03:04,880 SO SELF-CARE, IN ESSENCE, IS 5250 03:03:04,880 --> 03:03:07,520 PUSHED TO SAY, HEY, WE'RE 5251 03:03:07,520 --> 03:03:08,400 SERVING BUT WE DON'T WANT TO 5252 03:03:08,400 --> 03:03:14,880 SERVE FROM AN EMPTY PLACE. 5253 03:03:14,880 --> 03:03:17,800 THEN IN TERMS OF BARRIERS, WE 5254 03:03:17,800 --> 03:03:19,080 GOT A LOT MORE ABOUT BARRIERS 5255 03:03:19,080 --> 03:03:20,480 BECAUSE WE WERE REALLY ASKING 5256 03:03:20,480 --> 03:03:21,640 WHEN A PROGRAM DOESN'T WORK, WHY 5257 03:03:21,640 --> 03:03:22,400 DOESN'T IT WORK? 5258 03:03:22,400 --> 03:03:23,800 SO WE GOT A LOT OF INFORMATION 5259 03:03:23,800 --> 03:03:24,680 ON THIS. 5260 03:03:24,680 --> 03:03:26,920 FACTORS RELATED TO CULTURE, 5261 03:03:26,920 --> 03:03:29,400 208 IS THE ADDRESS OF THE 5262 03:03:29,400 --> 03:03:30,520 LEADERSHIP. 5263 03:03:30,520 --> 03:03:33,160 SO WE HEARD A LOT ABOUT 208 AND 5264 03:03:33,160 --> 03:03:34,680 A DISCONNECT BETWEEN 208 AND 5265 03:03:34,680 --> 03:03:36,080 WHAT'S REALLY GOING ON AT THE 5266 03:03:36,080 --> 03:03:37,240 SITE, AND THEN BARRIERS 5267 03:03:37,240 --> 03:03:38,040 ASSOCIATED WITH THE NATURE OF 5268 03:03:38,040 --> 03:03:47,480 THE WORK. 5269 03:03:47,480 --> 03:03:48,680 AN EXAMPLE OF THE DISCONNECT 5270 03:03:48,680 --> 03:03:50,000 BETWEEN THE LEADERSHIP AND THE 5271 03:03:50,000 --> 03:03:50,520 STAFF. 5272 03:03:50,520 --> 03:03:52,400 SO WE NEED TO BE AT THE TABLE 5273 03:03:52,400 --> 03:03:53,400 WHEN PROGRAMMATIC CHANGES ARE 5274 03:03:53,400 --> 03:03:54,800 BEING MADE SO OUR VOICES CAN BE 5275 03:03:54,800 --> 03:03:55,760 HEARD. 5276 03:03:55,760 --> 03:03:57,640 AS OPPOSED TO 208 MAKING THOSE 5277 03:03:57,640 --> 03:04:00,160 DESIXES AND ROLLING IT DOWN TO 5278 03:04:00,160 --> 03:04:02,720 US, AT THAT POINT IT'S NOT A 5279 03:04:02,720 --> 03:04:03,280 SUGGESTION, IT'S SOMETHING 5280 03:04:03,280 --> 03:04:04,360 THEY'RE GOING TO DO. 5281 03:04:04,360 --> 03:04:05,480 AND THEN AN EXAMPLE OF SORT OF 5282 03:04:05,480 --> 03:04:06,960 THE NATURE OF THE WORK AND THE 5283 03:04:06,960 --> 03:04:07,280 BARRIERS HERE. 5284 03:04:07,280 --> 03:04:08,600 AND THIS IS ABOUT PERSONAL 5285 03:04:08,600 --> 03:04:09,720 EXPERIENCES WITH TRAUMA AND HOW 5286 03:04:09,720 --> 03:04:10,920 THAT PLAYS OUT WHEN YOU'RE DOING 5287 03:04:10,920 --> 03:04:11,800 THIS KIND OF WORK. 5288 03:04:11,800 --> 03:04:13,440 SO EVERY DAY WE'RE DEALING WITH 5289 03:04:13,440 --> 03:04:14,320 TRAUMA, IT'S DIFFERENT FROM YOU 5290 03:04:14,320 --> 03:04:15,960 GOING TO A CORPORATE JOB AND 5291 03:04:15,960 --> 03:04:17,200 YOU'RE JUST GOING TO FOCUS ON 5292 03:04:17,200 --> 03:04:18,480 THAT JOB BUT IF YOU'RE DEALING 5293 03:04:18,480 --> 03:04:20,200 WITH TRAUMA AT HOME AND THEN YOU 5294 03:04:20,200 --> 03:04:21,920 HAVE TO COME IN AND TEACH OTHERS 5295 03:04:21,920 --> 03:04:24,080 HOWL OTHERS 5296 03:04:24,080 --> 03:04:28,240 HOW TO DEAL WITH TRAUMA, IT CAN 5297 03:04:28,240 --> 03:04:29,000 WEIGH HEAVILY, AND BLEED INTO 5298 03:04:29,000 --> 03:04:29,880 WHAT YOU'RE TRYING TO DO. 5299 03:04:29,880 --> 03:04:34,960 THEN IN TERMS OF CONTEXT, WE 5300 03:04:34,960 --> 03:04:37,800 CODED EVERY TIME WE SAW 5301 03:04:37,800 --> 03:04:38,440 SOMETHING ABOUT COVID, THE 5302 03:04:38,440 --> 03:04:41,720 NATURE OF STRESS AT READI AND 5303 03:04:41,720 --> 03:04:42,480 THE MEANING AND PURPOSE IN THEIR 5304 03:04:42,480 --> 03:04:42,720 WORK. 5305 03:04:42,720 --> 03:04:44,160 I KNOW THIS YEAR ALONE, I THINK 5306 03:04:44,160 --> 03:04:45,760 WE MAY HAVE LOST TWO OR THREE 5307 03:04:45,760 --> 03:04:46,080 PARTICIPANTS. 5308 03:04:46,080 --> 03:04:47,240 WHEN I SAY LOST, I MEAN DIED. 5309 03:04:47,240 --> 03:04:49,040 OF COURSE IT'S TRAUMATIC AND YOU 5310 03:04:49,040 --> 03:04:50,680 ATTEND THE FUNERAL BUT BY THE 5311 03:04:50,680 --> 03:04:51,360 SECOND OR THIRD TIME, IT'S HARD 5312 03:04:51,360 --> 03:04:52,680 TO HAVE THE STOMACH TO ATTEND 5313 03:04:52,680 --> 03:04:54,640 SOME OF THOSE FUNERALS ANYMORE. 5314 03:04:54,640 --> 03:04:56,280 YOUR SPIRIT IS KIND OF A BURNOUT 5315 03:04:56,280 --> 03:04:57,800 AND PEOPLE START TO DRAW 5316 03:04:57,800 --> 03:04:58,560 BOUNDARIES, THAT'S START REALLY 5317 03:04:58,560 --> 03:05:00,440 GETTING TO YOU, YOU CAN SEE 5318 03:05:00,440 --> 03:05:01,320 THEY'RE DRAWING MORE AND MORE 5319 03:05:01,320 --> 03:05:02,200 BOUNDARIES TO SOME OF THE THINGS 5320 03:05:02,200 --> 03:05:03,080 THEY'RE EXPERIENCING THROUGH THE 5321 03:05:03,080 --> 03:05:07,760 JOB OR EXPERIENCING VICARIOUSLY. 5322 03:05:07,760 --> 03:05:09,280 AND THEN WE HEARD A LOT ABOUT 5323 03:05:09,280 --> 03:05:11,240 THE SENSE OF MEANING AND PURPOSE 5324 03:05:11,240 --> 03:05:14,640 BEHIND THIS WORK. 5325 03:05:14,640 --> 03:05:16,400 I HAVE ONE JOB AT READI AND 5326 03:05:16,400 --> 03:05:18,240 THAT'S TO KEEP THESE GUYS ALIVE. 5327 03:05:18,240 --> 03:05:20,240 THAT'S THE ONLY JOB I HAVE. 5328 03:05:20,240 --> 03:05:21,440 EVERYTHING ELSE IS WORK. 5329 03:05:21,440 --> 03:05:27,280 YOU STAND WHAT I THERE IT 5330 03:05:27,280 --> 03:05:28,560 READI THAT I'VE COME ACROSS THAT 5331 03:05:28,560 --> 03:05:30,120 IS NOT THERE TO KEEP THESE YOUNG 5332 03:05:30,120 --> 03:05:31,200 BROTHERS ALIVE. 5333 03:05:31,200 --> 03:05:35,040 IT'S EXTREMELY DIFFICULT. 5334 03:05:35,040 --> 03:05:36,120 SO WE'RE IN THE PROCESS OF 5335 03:05:36,120 --> 03:05:37,360 REFINING AND FINALIZING THESE 5336 03:05:37,360 --> 03:05:40,680 CODES AND REVISING THE CONTENT 5337 03:05:40,680 --> 03:05:41,840 OF THE INTERVENTION. 5338 03:05:41,840 --> 03:05:43,280 WE'RE GOING TO FOLLOW UP WITH 5339 03:05:43,280 --> 03:05:46,200 MORE IN DEPTH INTERVIEWS ABOUT 5340 03:05:46,200 --> 03:05:47,960 THE INTERVIEWS AND POSSIBLE 5341 03:05:47,960 --> 03:05:49,000 IMPLEMENTATION AND WE'RE ALSO 5342 03:05:49,000 --> 03:05:49,920 GOING TO BE IDENTIFYING AND 5343 03:05:49,920 --> 03:05:50,920 TRAINING PERSONNEL IF WE'RE 5344 03:05:50,920 --> 03:05:52,320 GOING TO GO THIS TRAIN THE 5345 03:05:52,320 --> 03:05:54,080 TRAINERS ROUTE. 5346 03:05:54,080 --> 03:05:58,920 AND I THINK THAT'S IT. 5347 03:05:58,920 --> 03:06:01,520 >> YES. 5348 03:06:01,520 --> 03:06:02,280 WONDERFUL. 5349 03:06:02,280 --> 03:06:03,840 WELL, THANK YOU ALL SO MUCH. 5350 03:06:03,840 --> 03:06:07,440 I'M GOING TO STOP SHARING AND 5351 03:06:07,440 --> 03:06:08,680 BRING US BACK TO OUR SQUARES 5352 03:06:08,680 --> 03:06:09,880 WHERE WE CAN SEE EVERYBODY. 5353 03:06:09,880 --> 03:06:11,600 I'M SEEING SOME CLAPS AND SOME 5354 03:06:11,600 --> 03:06:11,960 APPLAUSE. 5355 03:06:11,960 --> 03:06:13,240 THE WORK THAT YOU ARE ALL DOING 5356 03:06:13,240 --> 03:06:17,840 IS JUST REALLY AMAZING, AND SO 5357 03:06:17,840 --> 03:06:19,280 I'LL OPEN IT UP IF PEOPLE WANT 5358 03:06:19,280 --> 03:06:20,000 TO ASK QUESTIONS. 5359 03:06:20,000 --> 03:06:21,240 I DID SEE A COUPLE OF THINGS IN 5360 03:06:21,240 --> 03:06:24,000 THE CHAT. 5361 03:06:24,000 --> 03:06:25,840 BUT I DON'T KNOW IF DR. LANGEVIN 5362 03:06:25,840 --> 03:06:27,240 OR IF YOU WANT TO START OFF, IF 5363 03:06:27,240 --> 03:06:28,360 YOU'VE GOT QUESTIONS AS WE'RE 5364 03:06:28,360 --> 03:06:30,240 WAITING FOR OTHERS TO USE 5365 03:06:30,240 --> 03:06:32,680 THEIR -- RAISE THEIR HAND 5366 03:06:32,680 --> 03:06:34,960 FUNCTION TO START THE 5367 03:06:34,960 --> 03:06:38,240 CONVERSATION. 5368 03:06:38,240 --> 03:06:39,640 >> THANK YOU, WENDY. 5369 03:06:39,640 --> 03:06:40,520 WOW, THIS WAS REALLY GREAT. 5370 03:06:40,520 --> 03:06:42,560 I HAD A QUESTION I ASKED IN THE 5371 03:06:42,560 --> 03:06:44,000 CHAT AND IT GOT ANSWERED, BUT 5372 03:06:44,000 --> 03:06:46,560 MAYBE I CAN JUST RAISE IT MORE 5373 03:06:46,560 --> 03:06:47,520 GENERALLY. 5374 03:06:47,520 --> 03:06:50,920 I'M REALLY CURIOUS ABOUT THIS 5375 03:06:50,920 --> 03:06:57,240 THING ABOUT HOW -- IS LESS MORE. 5376 03:06:57,240 --> 03:07:00,320 YOU KNOW, IF YOU SET THE 5377 03:07:00,320 --> 03:07:01,840 EXPECTATION THAT SOMEBODY IS 5378 03:07:01,840 --> 03:07:03,160 GOING TO DO A CERTAIN AMOUNT OF 5379 03:07:03,160 --> 03:07:04,480 PRACTICE EACH DAY OR THEY'RE 5380 03:07:04,480 --> 03:07:08,640 GOING TO HAVE A CERTAIN -- A 5381 03:07:08,640 --> 03:07:10,360 GOAL TO SET IN TERMS OF THEIR 5382 03:07:10,360 --> 03:07:13,000 PRACTICE, IS SETTING A SHORTER, 5383 03:07:13,000 --> 03:07:16,400 SMALLER, MORE PERHAPS ACHIEVABLE 5384 03:07:16,400 --> 03:07:17,960 GOAL BOTH MORE REALISTIC BUT 5385 03:07:17,960 --> 03:07:25,280 ALSO MAYBE EVEN BETTER IN TERMS 5386 03:07:25,280 --> 03:07:26,800 OF EMPOWERING THE INDIVIDUAL TO 5387 03:07:26,800 --> 03:07:28,120 DO SOMETHING, IF YOU SET THE 5388 03:07:28,120 --> 03:07:29,680 GOAL TOO HIGH OR LIKE SAY 5389 03:07:29,680 --> 03:07:31,280 PRACTICING FOR 30 OR 45 MINUTES 5390 03:07:31,280 --> 03:07:34,040 A DAY, IS THAT 5391 03:07:34,040 --> 03:07:34,600 COUNTERPRODUCTIVE? 5392 03:07:34,600 --> 03:07:37,760 I'M JUST WONDERING, I THINK THIS 5393 03:07:37,760 --> 03:07:39,400 IS A VERY INTERESTING QUESTION 5394 03:07:39,400 --> 03:07:41,080 AND I WAS JUST WONDERING IF ANY 5395 03:07:41,080 --> 03:07:43,880 OF YOU HAVE SORT OF EXAMINED 5396 03:07:43,880 --> 03:07:46,640 THAT SPECIFICALLY. 5397 03:07:46,640 --> 03:07:49,800 >> I DON'T KNOW, MICHAEL OR ZEV 5398 03:07:49,800 --> 03:07:51,000 OR JUDY IF YOU GUYS HAVE 5399 03:07:51,000 --> 03:07:57,680 THOUGHTS ON THAT? 5400 03:07:57,680 --> 03:07:58,680 MIKE, WHY DON'T YOU START. 5401 03:07:58,680 --> 03:08:01,840 >> I'LL KEEP MINE SHORT. 5402 03:08:01,840 --> 03:08:05,440 AS I MENTIONED IN THE CHAT, I 5403 03:08:05,440 --> 03:08:06,240 THINK THAT'S EXACTLY RIGHT. 5404 03:08:06,240 --> 03:08:07,440 I THINK THAT'S SORT OF WHAT WE 5405 03:08:07,440 --> 03:08:09,320 FOUND IN OUR STUDY. 5406 03:08:09,320 --> 03:08:13,480 WE NICHE INITIALLY BASED THI- 5407 03:08:13,480 --> 03:08:14,880 INITIAL 30, 45 MINUTES A DAY OF 5408 03:08:14,880 --> 03:08:17,440 PRACTICE AND I THINK YOU HIT IT 5409 03:08:17,440 --> 03:08:18,720 RIGHT ON THE HEAD, A LOT OF 5410 03:08:18,720 --> 03:08:20,360 FOLKS SAID I CAN'T DO THAT SO I 5411 03:08:20,360 --> 03:08:21,480 JUST WON'T DO ANYTHING. 5412 03:08:21,480 --> 03:08:24,440 WE HAVE SOME OF THAT IN OUR DATA 5413 03:08:24,440 --> 03:08:28,040 WHERE WE HAVE THEM SAY YOU'RE 5414 03:08:28,040 --> 03:08:29,760 ASKING US TO DO TOO MUCH. 5415 03:08:29,760 --> 03:08:32,760 SO WE DID DECREASE THAT REQUEST 5416 03:08:32,760 --> 03:08:34,400 AND WE REVIEWED IT A LITTLE MORE 5417 03:08:34,400 --> 03:08:35,360 CAREFULLY AT THE BEGINNING OF 5418 03:08:35,360 --> 03:08:36,000 EACH GROUP. 5419 03:08:36,000 --> 03:08:37,320 WE HAD THEM SET THEIR OWN 5420 03:08:37,320 --> 03:08:38,640 PERSONAL GOALS SO INSTEAD OF US 5421 03:08:38,640 --> 03:08:40,200 TELLING THEM YOU HAVE TO DO THIS 5422 03:08:40,200 --> 03:08:41,480 AMOUNT, LIKE WHAT'S RIGHT FOR 5423 03:08:41,480 --> 03:08:43,040 YOU, AND WE ADAPTED THAT 5424 03:08:43,040 --> 03:08:44,320 THROUGHOUT TREATMENT. 5425 03:08:44,320 --> 03:08:45,520 AND AGAIN, WE'RE JUST STARTING 5426 03:08:45,520 --> 03:08:46,600 TO LOOK AT THE DATA. 5427 03:08:46,600 --> 03:08:48,360 BUT SO FAR WE SUGGESTED WE HAD A 5428 03:08:48,360 --> 03:08:52,880 MUCH BETTER CONTINUE TO PRACTICE 5429 03:08:52,880 --> 03:08:53,320 AT SIX MONTHS OUT. 5430 03:08:53,320 --> 03:08:54,520 >> FUNNY BECAUSE WE USUALLY 5431 03:08:54,520 --> 03:08:56,360 THINK OF A DOSING EFFECT AS 5432 03:08:56,360 --> 03:08:57,520 BEING LINEAR, THE MORE YOU DO, 5433 03:08:57,520 --> 03:08:59,640 THE BETTER IT IS. 5434 03:08:59,640 --> 03:09:01,760 THIS MAY APPLY TO MORE THAN 5435 03:09:01,760 --> 03:09:06,400 MINDFULNESS. 5436 03:09:06,400 --> 03:09:10,360 >> IF I COULD SAY, THERE IS A 5437 03:09:10,360 --> 03:09:14,320 DOSING EFFECT, AND THE MORE YOU 5438 03:09:14,320 --> 03:09:15,640 PRACTICE, OFTEN WE SEE CHANGES 5439 03:09:15,640 --> 03:09:17,400 IN SYMPTOMS AND EVEN IN BRAIN 5440 03:09:17,400 --> 03:09:19,280 MECHANISMS. 5441 03:09:19,280 --> 03:09:20,880 BUT, IF IT'S TOO MUCH WHEN 5442 03:09:20,880 --> 03:09:22,880 YOU'RE STARTING AND YOU'RE 5443 03:09:22,880 --> 03:09:23,640 OVERWHELMED AND THAT LEADS YOU 5444 03:09:23,640 --> 03:09:24,920 TO FEEL LIKE YOU'RE SOMEONE WHO 5445 03:09:24,920 --> 03:09:27,920 CAN'T DO IT, OR TO FEEL BAD 5446 03:09:27,920 --> 03:09:28,760 ABOUT YOURSELF LIKE SOMETHING IS 5447 03:09:28,760 --> 03:09:29,960 WRONG WITH YOU, THEN THAT'S TOO 5448 03:09:29,960 --> 03:09:32,680 MUCH AND THERE WILL BE NO 5449 03:09:32,680 --> 03:09:33,360 PRACTICE. 5450 03:09:33,360 --> 03:09:34,720 SO SOME IS GOING TO BE BETTER 5451 03:09:34,720 --> 03:09:40,240 THAN NONE IN THAT CASE. 5452 03:09:40,240 --> 03:09:46,960 IN OUR PRIMARY CARE MINDFULNESS 5453 03:09:46,960 --> 03:09:48,920 STUDY, WE -- WE FOUND THAT 5454 03:09:48,920 --> 03:09:51,760 WITHIN EIGHT WEEKS, THE 5455 03:09:51,760 --> 03:09:53,200 EIGHT-WEEK PROGRAM HAD 5456 03:09:53,200 --> 03:09:56,680 SUBSTANTIAL REDUCTIONS IN 5457 03:09:56,680 --> 03:09:58,000 ANXIETY, DEPRESSION AND STRESS, 5458 03:09:58,000 --> 03:10:01,520 BUT BY 24 WEEKS, THE PEOPLE THAT 5459 03:10:01,520 --> 03:10:02,920 HAD ONE HOUR AND THEN REFERRAL 5460 03:10:02,920 --> 03:10:04,680 TO COMMUNITY PROGRAMS CAUGHT UP 5461 03:10:04,680 --> 03:10:07,200 AT LEAST WITHIN THE CONTEXT OF 5462 03:10:07,200 --> 03:10:07,840 STRESS. 5463 03:10:07,840 --> 03:10:10,920 WHAT WE DIDN'T SEE WAS THAT THE 5464 03:10:10,920 --> 03:10:13,000 PEOPLE THAT WENT TO THE 8-WEEK 5465 03:10:13,000 --> 03:10:16,720 GROUP WERE 2 1/2, 4 TIMES AS 5466 03:10:16,720 --> 03:10:18,880 LIKELY TO INITIATE A BEHAVIOR 5467 03:10:18,880 --> 03:10:20,040 CHANGE WITHIN TWO WEEKS, WHICH 5468 03:10:20,040 --> 03:10:21,560 WASN'T A PRIMARY OUT COME OF THE 5469 03:10:21,560 --> 03:10:23,640 STUDY. 5470 03:10:23,640 --> 03:10:25,720 2 1/2 TO 4 TIMES AS LIKELY AS 5471 03:10:25,720 --> 03:10:27,360 THE GROUP THAT ONLY GOT AN HOUR 5472 03:10:27,360 --> 03:10:28,960 OF MINDFULNESS. 5473 03:10:28,960 --> 03:10:30,400 AND THE CHANGES IN MECHANISMS 5474 03:10:30,400 --> 03:10:33,720 LIKE EMOTION REGULATION, 5475 03:10:33,720 --> 03:10:35,160 INTERCEPTIVE AWARENESS AND SELF 5476 03:10:35,160 --> 03:10:37,920 COMPASSION WERE MUCH LARGER 5477 03:10:37,920 --> 03:10:39,320 EFFECTS IN THE EIGHT-WEEK GROUP 5478 03:10:39,320 --> 03:10:42,960 COMPARED TO THE ONE HOUR GROUP. 5479 03:10:42,960 --> 03:10:49,920 SO I THINK THAT THERE IS A DOSE 5480 03:10:49,920 --> 03:10:51,600 EFFECT AND IF YOU DON'T TEACH IT 5481 03:10:51,600 --> 03:10:53,440 IN A MOTIVATIONALLY SALIENT WAY 5482 03:10:53,440 --> 03:10:54,440 AND YOU DON'T PAY ATTENTION TO 5483 03:10:54,440 --> 03:10:56,280 WHERE PEOPLE ARE AT, THEN YOU 5484 03:10:56,280 --> 03:10:57,480 WILL TURN A LOT OF PEOPLE OFF. 5485 03:10:57,480 --> 03:10:59,480 AND THE WORK WE'VE BEEN DOING 5486 03:10:59,480 --> 03:11:00,680 WITH ADICKS, WITH OPIATE USE 5487 03:11:00,680 --> 03:11:06,920 DISORDER, ADDIF 5488 03:11:06,920 --> 03:11:08,680 MINDFULNESS AND USE WHAT WE CALL 5489 03:11:08,680 --> 03:11:09,440 AN ASCENDING PRACTICE DOSE 5490 03:11:09,440 --> 03:11:10,880 LADDER SO WHEN PEOPLE 5491 03:11:10,880 --> 03:11:11,760 CONSOLIDATE IN THAT 10 MINUTES, 5492 03:11:11,760 --> 03:11:13,360 THEN THEY CAN GO TO 15 AND THEN 5493 03:11:13,360 --> 03:11:14,960 WHEN THEY GET TO 15 THEY CAN GO 5494 03:11:14,960 --> 03:11:15,640 TO 20. 5495 03:11:15,640 --> 03:11:17,360 BECAUSE THE RISKS IN OPIATE USE 5496 03:11:17,360 --> 03:11:18,760 DISORDER OF SOMEONE FEELING LIKE 5497 03:11:18,760 --> 03:11:19,960 THIS WON'T WORK FOR THEM OR I'M 5498 03:11:19,960 --> 03:11:21,720 NOT GOING TO BE GOOD ENOUGH, AND 5499 03:11:21,720 --> 03:11:23,000 THEN DROPPING OUT OF TREATMENT, 5500 03:11:23,000 --> 03:11:24,800 ARE REALLY HIGH. 5501 03:11:24,800 --> 03:11:26,520 SO WE WANT TO START SLOW AND 5502 03:11:26,520 --> 03:11:27,520 KIND OF GO WITH THEM. 5503 03:11:27,520 --> 03:11:29,240 BUT THAT COULD BE SAID FOR 5504 03:11:29,240 --> 03:11:33,240 NEARLY ANY POPULATION WHERE 5505 03:11:33,240 --> 03:11:36,280 MINDFULNESS IS NOT SOMETHING 5506 03:11:36,280 --> 03:11:40,200 THAT THEY'RE ACTIVELY COMING TO 5507 03:11:40,200 --> 03:11:41,800 AND WHERE MAYBE THERE WAS 5508 03:11:41,800 --> 03:11:42,680 IMPULSIVITY OR INTENTIONAL 5509 03:11:42,680 --> 03:11:44,200 CHALLENGES OR JUST REALLY 5510 03:11:44,200 --> 03:11:47,600 INTENSE STRESS FOR TRAUMA, THAT 5511 03:11:47,600 --> 03:11:51,200 PEOPLE NEED TO BE ABLE TO GET 5512 03:11:51,200 --> 03:11:55,480 COACHING AROUND HOW TO BE WITH 5513 03:11:55,480 --> 03:11:57,360 AND HOW TO BE KIND TO THEMSELVES 5514 03:11:57,360 --> 03:11:59,160 AROUND, BEFORE THEY ACTUALLY CAN 5515 03:11:59,160 --> 03:12:00,600 MOVE ON AND DO THE PRACTICE. 5516 03:12:00,600 --> 03:12:02,760 THIS IS WHY WE'VE BEEN WORKING A 5517 03:12:02,760 --> 03:12:04,760 LOT AROUND THIS IDEA OF WARM 5518 03:12:04,760 --> 03:12:06,400 MINDFULNESS OR INTEGRATING SELF 5519 03:12:06,400 --> 03:12:09,920 COMPASSION AND MINDFULNESS MORE 5520 03:12:09,920 --> 03:12:11,080 EXPLICITLY BECAUSE ESPECIALLY IN 5521 03:12:11,080 --> 03:12:13,440 THE U.S., I THINK PEOPLE NEED 5522 03:12:13,440 --> 03:12:14,520 TO -- NEED TO KNOW HOW TO BE 5523 03:12:14,520 --> 03:12:15,920 KIND TO THEMSELVES IN ORDER TO 5524 03:12:15,920 --> 03:12:19,040 THEN BE ABLE TO TOLERATE THAT 5525 03:12:19,040 --> 03:12:20,440 MAYBE THEY CAN'T DO 30 MINUTES 5526 03:12:20,440 --> 03:12:20,880 RIGHT AWAY. 5527 03:12:20,880 --> 03:12:22,120 MAYBE THIS IS HARD. 5528 03:12:22,120 --> 03:12:24,080 MAYBE I CAN BE OKAY WITH THAT. 5529 03:12:24,080 --> 03:12:25,600 MAIBL I'M OKAY HOW I AM AND I 5530 03:12:25,600 --> 03:12:26,920 CAN BE KIND TO MYSELF AND THAT 5531 03:12:26,920 --> 03:12:28,240 ACTUALLY CAN ALLOW PEOPLE TO 5532 03:12:28,240 --> 03:12:29,600 THEN STICK WITH THE PRACTICE IN 5533 03:12:29,600 --> 03:12:32,280 THE LONG TERM. 5534 03:12:32,280 --> 03:12:33,600 I WON'T SAY ANY MORE. 5535 03:12:33,600 --> 03:12:34,840 THOSE ARE MY THOUGHTS ON IT. 5536 03:12:34,840 --> 03:12:35,760 >> WONDERFUL. 5537 03:12:35,760 --> 03:12:37,760 SO I SEE WE'VE GOT A SEER EAVES 5538 03:12:37,760 --> 03:12:39,720 HANDS UP. 5539 03:12:39,720 --> 03:12:40,080 SERIES OF 5540 03:12:40,080 --> 03:12:41,040 HANDS UP. 5541 03:12:41,040 --> 03:12:42,240 RICK, I'LL START WITH YOU. 5542 03:12:42,240 --> 03:12:43,200 >> I'LL JUST CHIME IN. 5543 03:12:43,200 --> 03:12:44,320 I LOVE THAT QUESTION THAT 5544 03:12:44,320 --> 03:12:45,120 DR. LANGEVIN POSED ABOUT THE 5545 03:12:45,120 --> 03:12:45,960 DOSE. 5546 03:12:45,960 --> 03:12:47,240 WE'VE DONE A CLASS HERE AT THE 5547 03:12:47,240 --> 03:12:49,480 UNIVERSITY OF MICHIGAN WHERE WE 5548 03:12:49,480 --> 03:12:51,760 TEACH GRADUATE STUDENTS 5549 03:12:51,760 --> 03:12:52,880 MINDFULNESS-BASED MEDITATION AS 5550 03:12:52,880 --> 03:12:55,280 A COURSE FOR JUST ONE SEMESTER, 5551 03:12:55,280 --> 03:12:57,440 AND WE HAVE THEM MEDITATE FOR 5552 03:12:57,440 --> 03:12:59,120 JUST FIVE MINUTES A DAY, AND 5553 03:12:59,120 --> 03:13:00,960 THEN TO DO A SHORT JOURNALING 5554 03:13:00,960 --> 03:13:01,440 DAILY. 5555 03:13:01,440 --> 03:13:02,480 THAT'S THE ONLY THING THAT WE 5556 03:13:02,480 --> 03:13:06,560 REALLY REQUIRE OF THEM, OF THE 5557 03:13:06,560 --> 03:13:07,640 CLASS. 5558 03:13:07,640 --> 03:13:09,080 WE HAD THEM THROW AWAY THEIR 5559 03:13:09,080 --> 03:13:09,720 READING, DON'T THINK ABOUT 5560 03:13:09,720 --> 03:13:10,400 MAKING A PRESENTATION. 5561 03:13:10,400 --> 03:13:11,880 WE JUST WANT YOU TO WORK WITH 5562 03:13:11,880 --> 03:13:13,240 YOUR MIND DURING THE COURSE. 5563 03:13:13,240 --> 03:13:15,960 AND WE HAD -- WE'VE DONE THIS 5564 03:13:15,960 --> 03:13:18,920 NOW FOR FOUR SEMESTERS, AND WE 5565 03:13:18,920 --> 03:13:22,000 HAVE 35 TO 40% REDUCTION IN 5566 03:13:22,000 --> 03:13:25,360 ANXIETY AND DEPRESSION IN THESE 5567 03:13:25,360 --> 03:13:27,680 GRADUATE STUDENTS THAT'S 5568 03:13:27,680 --> 03:13:29,640 CLINICALLY AS WELL AS 5569 03:13:29,640 --> 03:13:30,560 STATISTICALLY REALLY 5570 03:13:30,560 --> 03:13:30,840 SIGNIFICANT. 5571 03:13:30,840 --> 03:13:33,400 SO I DO AGREE THAT A SHORTER 5572 03:13:33,400 --> 03:13:35,800 DOSE OR LIKE A SHORTER TIME OF 5573 03:13:35,800 --> 03:13:38,320 MEDITATION CAN REALLY BE 5574 03:13:38,320 --> 03:13:41,480 EFFECTIVE, ESPECIALLY WHEN 5575 03:13:41,480 --> 03:13:43,240 YOU'RE LEARNING THE TECHNIQUE & 5576 03:13:43,240 --> 03:13:43,640 GETTING IT GOING. 5577 03:13:43,640 --> 03:13:45,200 SO I DO THINK A SMALL DOSE CAN 5578 03:13:45,200 --> 03:13:53,880 BE HELPFUL. 5579 03:13:53,880 --> 03:13:54,400 >> KAREN? 5580 03:13:54,400 --> 03:13:56,120 >> THE ISSUE I WANTED TO RAISE 5581 03:13:56,120 --> 03:13:57,320 IS SORT OF THE NEXT STEP AFTER 5582 03:13:57,320 --> 03:13:57,680 THAT. 5583 03:13:57,680 --> 03:13:59,440 AFTER YOU HAVE ENOUGH OF 5584 03:13:59,440 --> 03:14:00,440 EXPERIENCE WITH, SAY, 5585 03:14:00,440 --> 03:14:01,640 MINDFULNESS, THAT YOU RECOGNIZE 5586 03:14:01,640 --> 03:14:05,040 YOU'RE NOT GOING TO FALL APART, 5587 03:14:05,040 --> 03:14:06,200 THAT YOUR THOUGHTS DON'T OWN YOU 5588 03:14:06,200 --> 03:14:08,000 AND ALL THAT SORT OF STUFF, THEN 5589 03:14:08,000 --> 03:14:10,920 THE QUESTION BECOMES HOW TO TAKE 5590 03:14:10,920 --> 03:14:12,440 THAT FROM YOUR FIVE MINUTE OR 5591 03:14:12,440 --> 03:14:14,560 YOUR 10 MINUTE OR YOUR 30 MINUTE 5592 03:14:14,560 --> 03:14:15,760 EXPERIENCE EVERY MORNING OR 5593 03:14:15,760 --> 03:14:17,680 WHENEVER YOU DO TO THROUGHOUT 5594 03:14:17,680 --> 03:14:22,760 THE DAY. 5595 03:14:22,760 --> 03:14:23,600 IN MY PERSONAL EXPERIENCE AS 5596 03:14:23,600 --> 03:14:25,280 WELL AS AS A RESEARCHER, THAT 5597 03:14:25,280 --> 03:14:31,080 PIECE HAS BEEN MUCH HARDER TO 5598 03:14:31,080 --> 03:14:31,520 FIGURE OUT. 5599 03:14:31,520 --> 03:14:32,760 I FINALLY JUST STARTED 5600 03:14:32,760 --> 03:14:34,040 PROGRAMMING MY CELL PHONE TO GO 5601 03:14:34,040 --> 03:14:35,360 OFF EVERY SO OFTEN AND BEEP AT 5602 03:14:35,360 --> 03:14:38,760 ME AND IT'S, OH, YES, I PRESENCE 5603 03:14:38,760 --> 03:14:39,000 MYSELF. 5604 03:14:39,000 --> 03:14:41,920 BUT I HAVEN'T REALLY READ MUCH 5605 03:14:41,920 --> 03:14:45,440 ABOUT THAT IN SORT OF A SPECIFIC 5606 03:14:45,440 --> 03:14:46,320 PROBLEM-SOLVING WAY IN THE 5607 03:14:46,320 --> 03:14:48,680 RESEARCH LITERATURE, AND I THINK 5608 03:14:48,680 --> 03:14:50,680 IT WOULD BE FUN TO HEAR YOU GUYS 5609 03:14:50,680 --> 03:14:58,160 ALL COMMENT ON THAT. 5610 03:14:58,160 --> 03:14:59,440 >> I CAN SPEAK TO MY THOUGHTS ON 5611 03:14:59,440 --> 03:14:59,880 THAT. 5612 03:14:59,880 --> 03:15:01,720 WHEN I WAS DOING SOME WORK WITH 5613 03:15:01,720 --> 03:15:03,080 THE DEFAULT NETWORK AND THINKING 5614 03:15:03,080 --> 03:15:06,560 ABOUT INTENTIONAL PATHWAYS AND 5615 03:15:06,560 --> 03:15:10,040 IT SEEMED TO ME THAT WE TEND TO 5616 03:15:10,040 --> 03:15:10,960 MIND WANDER WITHIN 6 TO 5617 03:15:10,960 --> 03:15:12,160 8 SECONDS OF ANY MOMENT THAT WE 5618 03:15:12,160 --> 03:15:15,200 ARE ACTUALLY PAYING ATTENTION TO 5619 03:15:15,200 --> 03:15:16,240 SOMETHING. 5620 03:15:16,240 --> 03:15:18,920 AND SO I DID A BACK OF THE 5621 03:15:18,920 --> 03:15:20,800 ENVELOPE KIND OF CALCULATION AT 5622 03:15:20,800 --> 03:15:21,760 SOME POINT WHERE I THOUGHT ABOUT 5623 03:15:21,760 --> 03:15:22,840 THAT AND THOUGHT ABOUT HOW MANY 5624 03:15:22,840 --> 03:15:24,080 MINUTES OF SITTING AND LETTING 5625 03:15:24,080 --> 03:15:25,600 YOUR MIND WANDER AND COMING BACK 5626 03:15:25,600 --> 03:15:29,960 AGAIN WOULD TAKE TO BE ABLE 5627 03:15:29,960 --> 03:15:31,840 TO -- UNTIL THIS KIND OF BECOMES 5628 03:15:31,840 --> 03:15:36,000 MORE AUTOMATED, AND IN THESE 5629 03:15:36,000 --> 03:15:38,720 EIGHT-WEEK PROGRAMS, THAT 30 5630 03:15:38,720 --> 03:15:44,320 MINUTES A DAY, YOU WOULD DO THAT 5631 03:15:44,320 --> 03:15:46,040 ABOUT 10,000 TIMES AROUND WEEK 5632 03:15:46,040 --> 03:15:46,200 SIX. 5633 03:15:46,200 --> 03:15:47,280 THAT'S A BACK OF THE ENVELOPE 5634 03:15:47,280 --> 03:15:49,120 KIND OF DISCUSSION, NOT 5635 03:15:49,120 --> 03:15:50,560 SCIENTIFIC, SO I WANT TO 5636 03:15:50,560 --> 03:15:51,320 ACKNOWLEDGE THAT AND I'M 5637 03:15:51,320 --> 03:15:53,640 BRINGING THAT EVEN HERE INTO 5638 03:15:53,640 --> 03:15:57,360 THAT ADVISORY COUNCIL, BUT I DO 5639 03:15:57,360 --> 03:15:59,680 THINK THAT THERE IS THIS WHAT'S 5640 03:15:59,680 --> 03:16:00,880 CALLED CULTIVATION OF 5641 03:16:00,880 --> 03:16:02,400 MINDFULNESS SO THAT IT'S NOT 5642 03:16:02,400 --> 03:16:05,320 JUST EFFORTFUL TO TRY TO PAY 5643 03:16:05,320 --> 03:16:06,320 ATTENTION IN THE MOMENT, WHERE 5644 03:16:06,320 --> 03:16:07,640 YOU'RE CONSTANTLY REMINDING 5645 03:16:07,640 --> 03:16:09,040 YOURSELF, BUT WHERE ACTUALLY, I 5646 03:16:09,040 --> 03:16:10,360 HEAR THIS ALL THE TIME FROM 5647 03:16:10,360 --> 03:16:12,560 PEOPLE I'VE WORKED WITH, I'M 5648 03:16:12,560 --> 03:16:16,160 WALKING ACROSS THE STREET AND 5649 03:16:16,160 --> 03:16:20,560 SLOWLY -- MY BREATH. 5650 03:16:20,560 --> 03:16:21,760 SOMEWHERE AROUND FOUR, FIVE, SIX 5651 03:16:21,760 --> 03:16:22,840 WEEKS, THAT'S WHERE I THINK A 5652 03:16:22,840 --> 03:16:24,440 LOT OF THE EASE STARTS COMING, 5653 03:16:24,440 --> 03:16:25,680 WHEN PEOPLE ACTUALLY START TO 5654 03:16:25,680 --> 03:16:27,640 PAY ATTENTION TO THE PRESENT 5655 03:16:27,640 --> 03:16:29,960 MOMENT, TO THEIR BODY, AND 5656 03:16:29,960 --> 03:16:31,280 SOMETIMES IT TAKES EVEN LONGER 5657 03:16:31,280 --> 03:16:37,400 THAN THAT. 5658 03:16:37,400 --> 03:16:38,520 THAT MAY DEPEND ON MANY 5659 03:16:38,520 --> 03:16:40,760 DIFFERENT THINGS, BUT THAT'S HOW 5660 03:16:40,760 --> 03:16:42,720 HE 5661 03:16:42,720 --> 03:16:44,960 I SEE THESE, WHERE IT CAN START 5662 03:16:44,960 --> 03:16:46,360 TO COME ON AUTOMATICALLY AND 5663 03:16:46,360 --> 03:16:47,720 THEN YOU CAN CULTIVATE AND KEEP 5664 03:16:47,720 --> 03:16:49,560 THAT GOING. 5665 03:16:49,560 --> 03:16:55,680 BUT IT MAY HAPPEN MORE EASILY, 5666 03:16:55,680 --> 03:16:56,360 QUICKER, FOR OTHER PEOPLE WITH 5667 03:16:56,360 --> 03:16:57,600 OTHER TRAINING PATHWAYS. 5668 03:16:57,600 --> 03:17:02,640 >> JUDY OR MIKE? 5669 03:17:02,640 --> 03:17:03,880 >> I'D LIKE TO ADD TO THAT. 5670 03:17:03,880 --> 03:17:05,320 >> I'LL BRIEFLY ADD THAT WE'VE 5671 03:17:05,320 --> 03:17:07,200 BEEN VERY INTERESTED IN THE 5672 03:17:07,200 --> 03:17:08,400 DISTINCTION, I GUESS WHAT WE 5673 03:17:08,400 --> 03:17:11,320 CALL FORMAL VERSUS INFORMAL. 5674 03:17:11,320 --> 03:17:15,120 WE TEACH THAT IN OUR COURSE OF 5675 03:17:15,120 --> 03:17:16,640 THE FOUNDATION FIRST AND 5676 03:17:16,640 --> 03:17:19,560 BUILDING THROUGHOUT THE DAY. 5677 03:17:19,560 --> 03:17:21,400 I DIDN'T MENTION IN THE TALK, WE 5678 03:17:21,400 --> 03:17:23,040 HAVE SOME DATA WE LOOKED AT AS 5679 03:17:23,040 --> 03:17:25,720 WELL OF -- WE -- TO GET A SENSE 5680 03:17:25,720 --> 03:17:27,360 OF WHEN THEY WERE ENGAGING AND 5681 03:17:27,360 --> 03:17:29,840 HOW OFTEN IN INFORMAL PRACTICE. 5682 03:17:29,840 --> 03:17:32,040 SO WE PLAN TO LOOK AT THAT 5683 03:17:32,040 --> 03:17:33,440 ACTUALLY AS ONE OF OUR GOALS, TO 5684 03:17:33,440 --> 03:17:37,000 LOOK AT SECONDARY ANALYSIS, WHAT 5685 03:17:37,000 --> 03:17:37,840 ACCOUNTED FOR MORE POTENTIAL AND 5686 03:17:37,840 --> 03:17:39,720 MORE LINKS WITH THEIR OUTCOMES, 5687 03:17:39,720 --> 03:17:41,480 WAS IT FORMAL, INFORMAL OR BOTH. 5688 03:17:41,480 --> 03:17:42,680 WE'VE DONE THIS IN PREVIOUS 5689 03:17:42,680 --> 03:17:43,720 STUDIES. 5690 03:17:43,720 --> 03:17:45,720 IT'S BEEN ABOUT EQUAL, SO THAT 5691 03:17:45,720 --> 03:17:46,840 INFORMAL PRACTICE, KAREN, BACK 5692 03:17:46,840 --> 03:17:48,920 TO YOUR QUESTION IS CERTAINLY -- 5693 03:17:48,920 --> 03:17:50,600 IS SOMETHING BUILDING ON THE FOR 5694 03:17:50,600 --> 03:17:51,440 MALPRACTICE, WE'VE DONE SOME OF 5695 03:17:51,440 --> 03:17:54,960 THIS WORK WITH ER PHYSICIANS TO 5696 03:17:54,960 --> 03:17:56,160 SUGGEST THAT THOSE INFORMAL 5697 03:17:56,160 --> 03:17:57,360 MOMENTS OF MEDITATION ARE AS 5698 03:17:57,360 --> 03:17:58,480 IMPORTANT AS GETTING ON THE 5699 03:17:58,480 --> 03:17:59,000 CUSHION. 5700 03:17:59,000 --> 03:18:01,400 BUT IT SEEMS LIKE THAT NEEDS TO 5701 03:18:01,400 --> 03:18:05,160 PRECEDE SORT OF THEN DOING THAT. 5702 03:18:05,160 --> 03:18:05,920 >> GREAT. 5703 03:18:05,920 --> 03:18:06,680 THANKS. 5704 03:18:06,680 --> 03:18:07,520 RONI? 5705 03:18:07,520 --> 03:18:11,840 >> I JUST WANT TO THANK THE 5706 03:18:11,840 --> 03:18:13,120 PRESENTERS FOR THESE GREAT 5707 03:18:13,120 --> 03:18:15,440 PRESENTATIONS AND PROVOKING SO 5708 03:18:15,440 --> 03:18:17,200 MUCH INTEREST. 5709 03:18:17,200 --> 03:18:18,600 IT'S EXCITING TO HEAR YOUR WORK. 5710 03:18:18,600 --> 03:18:25,520 I COMMEND YOU FOR GETTING 5711 03:18:25,520 --> 03:18:27,000 THROUGH THOSE HARD TIMES AT THE 5712 03:18:27,000 --> 03:18:29,240 BEGINNING OF THE PAN PANDEMIC. 5713 03:18:29,240 --> 03:18:31,760 TRYING TO DO THE SAME THINGS IN 5714 03:18:31,760 --> 03:18:32,840 MINNEAPOLIS, AT THE TIME OF 5715 03:18:32,840 --> 03:18:38,360 GEORGE FLOOD'S MURDER AS , 5716 03:18:38,360 --> 03:18:39,560 IT'S JUST INCREDIBLE WHAT YOU 5717 03:18:39,560 --> 03:18:40,840 WERE ABLE TO ACCOMPLISH. 5718 03:18:40,840 --> 03:18:42,200 AS WE MOVE FORWARD, A LOT OF 5719 03:18:42,200 --> 03:18:44,160 PEOPLE CAN FORGET THAT. 5720 03:18:44,160 --> 03:18:45,680 SO JUST CONGRATULATIONS. 5721 03:18:45,680 --> 03:18:47,760 I THINK THESE CONVERSATIONS 5722 03:18:47,760 --> 03:18:50,480 ABOUT DOSE AND HOW IT RELATE TO 5723 03:18:50,480 --> 03:18:53,000 ADHERENCE AND ENGAGEMENT ARE SO 5724 03:18:53,000 --> 03:18:53,280 IMPORTANT. 5725 03:18:53,280 --> 03:18:57,280 I'D LOVE TO SEE ANOTHER SERIES 5726 03:18:57,280 --> 03:18:58,360 OF PRESENTATIONS ON THAT AT 5727 03:18:58,360 --> 03:18:59,920 MAYBE THE NEXT COUNCIL MEETING, 5728 03:18:59,920 --> 03:19:01,880 BECAUSE I THINK IT'S SO 5729 03:19:01,880 --> 03:19:02,160 CRITICAL. 5730 03:19:02,160 --> 03:19:04,360 AND I GUESS I HAVE A QUESTION TO 5731 03:19:04,360 --> 03:19:05,280 THE PRESENTERS. 5732 03:19:05,280 --> 03:19:07,360 BACK TO THIS DEALING WITH THE 5733 03:19:07,360 --> 03:19:09,280 TIME OF COVID, FOR THOSE OF YOU 5734 03:19:09,280 --> 03:19:12,520 THAT WERE CAUGHT MIDSTREAM, HOW 5735 03:19:12,520 --> 03:19:14,120 DO YOU DEAL WITH THIS IN THE 5736 03:19:14,120 --> 03:19:17,760 ANALYSIS AND HOW DO YOU -- WHAT 5737 03:19:17,760 --> 03:19:19,520 DO WE HAVE TO LOOK FORWARD TO IN 5738 03:19:19,520 --> 03:19:21,080 OUR STATISTICAL ANALYSIS? 5739 03:19:21,080 --> 03:19:22,360 BECAUSE WE'RE NOT DONE YET. 5740 03:19:22,360 --> 03:19:25,520 NOT ONLY DID COVID JUST APPEAR, 5741 03:19:25,520 --> 03:19:27,600 BUT THIS INCREASING STRESS THAT 5742 03:19:27,600 --> 03:19:30,920 WE'RE SEEING, HOW IS THAT GOING 5743 03:19:30,920 --> 03:19:32,560 TO AFFECT THINGS? 5744 03:19:32,560 --> 03:19:35,360 SO I JUST WONDER IF YOU GUYS ARE 5745 03:19:35,360 --> 03:19:36,920 THINKING ABOUT THAT LOOKING 5746 03:19:36,920 --> 03:19:37,760 FORWARD, BECAUSE THAT'S 5747 03:19:37,760 --> 03:19:40,760 SOMETHING THAT'S ON MY MIND A 5748 03:19:40,760 --> 03:19:40,920 LOT. 5749 03:19:40,920 --> 03:19:42,480 >> I CAN SPEAK TO THAT A LITTLE 5750 03:19:42,480 --> 03:19:43,920 BIT WITH OUR OTHER TRIALS. 5751 03:19:43,920 --> 03:19:45,800 I GUESS THE BLESSING IS THAT 5752 03:19:45,800 --> 03:19:51,160 WE'RE ALL GOING THROUGH THIS. 5753 03:19:51,160 --> 03:19:52,760 SO YOUR CONTROL GROUP AND YOUR 5754 03:19:52,760 --> 03:19:54,080 INTERVENTION ARE GOING THROUGH 5755 03:19:54,080 --> 03:19:56,480 THIS SAME STRESS AT LEAST WRIT 5756 03:19:56,480 --> 03:19:58,680 LARGE, AND THEN THERE WILL BE 5757 03:19:58,680 --> 03:19:59,680 THE NORMAL INDIVIDUAL DIFFERENCE 5758 03:19:59,680 --> 03:20:01,040 VARIATION AROUND THEIR REACTIONS 5759 03:20:01,040 --> 03:20:02,520 TO IT. 5760 03:20:02,520 --> 03:20:04,160 THAT SHOULD WASH OUT ACROSS THE 5761 03:20:04,160 --> 03:20:05,920 GROUPS. 5762 03:20:05,920 --> 03:20:10,360 LIKE I SHOWED YOU IN OUR FOCUS 5763 03:20:10,360 --> 03:20:14,200 GROUPS, WE'RE CODING THE COVID 5764 03:20:14,200 --> 03:20:16,000 PIECE BECAUSE LIKELY THAT'S 5765 03:20:16,000 --> 03:20:16,960 STILL GOING TO BE THERE GOING 5766 03:20:16,960 --> 03:20:18,160 FORWARD AND WE NEED TO KEEP THAT 5767 03:20:18,160 --> 03:20:19,880 IN MIND IF THEY'RE GOING BACK 5768 03:20:19,880 --> 03:20:20,800 AND FORTH BETWEEN BEING IN 5769 03:20:20,800 --> 03:20:22,080 PERSON AND BEING VIRTUAL AND 5770 03:20:22,080 --> 03:20:22,960 TRYING TO DO THEIR PROGRAM 5771 03:20:22,960 --> 03:20:23,640 VIRTUALLY AND THE DIFFERENT 5772 03:20:23,640 --> 03:20:24,840 SITES ARE DOING IT DIFFERENTLY, 5773 03:20:24,840 --> 03:20:28,760 WHICH IS WHAT WE WERE HEARING, 5774 03:20:28,760 --> 03:20:30,000 WE NEED TO TAKE THAT INTO 5775 03:20:30,000 --> 03:20:32,160 ACCOUNT AND AS WE'RE TRYING TO 5776 03:20:32,160 --> 03:20:32,920 DESIGN A PROGRAM THAT IS GOING 5777 03:20:32,920 --> 03:20:35,120 TO BE ROLLED OUT DURING COVID, 5778 03:20:35,120 --> 03:20:36,760 THERE'S JUST NO -- YOU NE OH. 5779 03:20:36,760 --> 03:20:40,360 UNLESS WE WAIT A DECADE, IT'S 5780 03:20:40,360 --> 03:20:43,880 STILL GOING TO BE AN ISSUE. 5781 03:20:43,880 --> 03:20:46,000 >> I THINK, JUDY, YOU BRING UP A 5782 03:20:46,000 --> 03:20:46,760 REALLY GOOD POINT. 5783 03:20:46,760 --> 03:20:50,560 I KNOW THIS IS SOMETHING, 5784 03:20:50,560 --> 03:20:51,440 EARLIER TODAY WE'VE BEEN TALKING 5785 03:20:51,440 --> 03:20:53,400 ABOUT SOME OF OUR PRAGMATIC 5786 03:20:53,400 --> 03:20:54,920 TRIALS WE'RE DOING, SOME OF THE 5787 03:20:54,920 --> 03:20:56,320 COLLABORATORY PROGRAMS, AND BOTH 5788 03:20:56,320 --> 03:20:59,640 IN THE NIH DOD PAIN MANAGEMENT 5789 03:20:59,640 --> 03:21:01,080 COLLABORATORY AND IN THE 5790 03:21:01,080 --> 03:21:03,600 PRAGMATIC TRIALS COLLABORATORY, 5791 03:21:03,600 --> 03:21:04,520 THEY'RE WORKING WITH A LOT OF 5792 03:21:04,520 --> 03:21:06,640 THOSE TRIALS TO TRY TO FIND SOME 5793 03:21:06,640 --> 03:21:08,040 LESSONS AND LOOK AT HOW THEY'RE 5794 03:21:08,040 --> 03:21:09,240 GOING TO MANAGE THAT 5795 03:21:09,240 --> 03:21:10,320 STATISTICALLY, SO I DO 5796 03:21:10,320 --> 03:21:13,840 ANTICIPATE SOME PUBLICATIONS 5797 03:21:13,840 --> 03:21:14,800 COMING FORWARD AND I'LL LOOK AND 5798 03:21:14,800 --> 03:21:16,600 SEE IF THERE'S ANYTHING I'LL PUT 5799 03:21:16,600 --> 03:21:18,160 IN THE CHAT FOR OTHER 5800 03:21:18,160 --> 03:21:19,440 PUBLICATIONS ABOUT HOW TO HANDLE 5801 03:21:19,440 --> 03:21:23,040 THIS, AND THE TRIALS THAT WERE 5802 03:21:23,040 --> 03:21:27,640 MOST DISRUPTED HONESTLY WERE THE 5803 03:21:27,640 --> 03:21:29,280 STEPPED WEDGE DESIGNS, THOSE 5804 03:21:29,280 --> 03:21:33,040 RANDOMIZING THE ORDER OF ROLLOUT 5805 03:21:33,040 --> 03:21:35,160 BECAUSE THE BASE WAS DIFFERENT 5806 03:21:35,160 --> 03:21:35,760 FOR EVERYBODY. 5807 03:21:35,760 --> 03:21:37,280 BUT IF YOU HAVE A PARALLEL GROUP 5808 03:21:37,280 --> 03:21:39,400 DESIGN, YOU SORT OF HAVE A PRE 5809 03:21:39,400 --> 03:21:41,680 AND A POST OR A PRE AND MID AND 5810 03:21:41,680 --> 03:21:43,080 POST, DEPENDING ON HOW THINGS 5811 03:21:43,080 --> 03:21:45,360 WENT, AND SO I THINK A LOT OF 5812 03:21:45,360 --> 03:21:46,800 OUR BIOSTATISTICIANS ARE LOOKING 5813 03:21:46,800 --> 03:21:49,320 AT THESE ISSUES AND MAKING SOME 5814 03:21:49,320 --> 03:21:49,960 RECOMMENDATIONS ACROSS THE 5815 03:21:49,960 --> 03:21:51,400 TRIAL, SO HOPEFULLY WE'LL GET 5816 03:21:51,400 --> 03:21:52,720 SOME MORE INFORMATION OUT TO THE 5817 03:21:52,720 --> 03:21:53,680 BROADER COMMUNITY ABOUT HOW SOME 5818 03:21:53,680 --> 03:21:55,200 OF THE STUDIES ARE APPROACHING 5819 03:21:55,200 --> 03:21:55,440 IT. 5820 03:21:55,440 --> 03:22:00,600 I DON'T KNOW THAT WE HAVE THE 5821 03:22:00,600 --> 03:22:02,320 ANSWERS, BUT HOW DIFFERENT 5822 03:22:02,320 --> 03:22:03,080 GROUPS ARE LOOKING AT IT. 5823 03:22:03,080 --> 03:22:06,680 GREAT QUESTION, RONI. 5824 03:22:06,680 --> 03:22:10,000 HELEN. 5825 03:22:10,000 --> 03:22:12,080 >> YES. 5826 03:22:12,080 --> 03:22:15,680 SO I HAD A COUPLE OF COMMENTS ON 5827 03:22:15,680 --> 03:22:16,680 THE GRAVITY OF THE 5828 03:22:16,680 --> 03:22:17,200 INTERVENTIONS. 5829 03:22:17,200 --> 03:22:19,960 IT'S BEEN STUDIED AND BRIEF 5830 03:22:19,960 --> 03:22:21,360 INTERVENTIONS DO -- MY STUDY 5831 03:22:21,360 --> 03:22:25,560 SHOWED THE 11 MINUTE MEDITATION 5832 03:22:25,560 --> 03:22:27,000 RESULTED IN PROFOUND BIOLOGICAL 5833 03:22:27,000 --> 03:22:27,400 CHANGES. 5834 03:22:27,400 --> 03:22:31,200 SO WHAT I'M STRUGGLING WITH IS 5835 03:22:31,200 --> 03:22:34,840 PATIENT PREFERENCES, AND THOSE 5836 03:22:34,840 --> 03:22:37,680 ARE RARELY INCLUDED IN THE 5837 03:22:37,680 --> 03:22:39,560 DESIGNS, AND WE KNOW IF PATIENTS 5838 03:22:39,560 --> 03:22:41,000 DON'T LIKE AN INTERVENTION, THEY 5839 03:22:41,000 --> 03:22:41,880 WILL NOT DO IT. 5840 03:22:41,880 --> 03:22:45,920 SO ADD SHEERNS ENTIRELY DEPENDS 5841 03:22:45,920 --> 03:22:46,720 ON PATIENT PREFERENCES. 5842 03:22:46,720 --> 03:22:47,760 AND I THINK THAT'S SOMETHING 5843 03:22:47,760 --> 03:22:50,160 THAT NEEDS TO BE INTEGRATED INTO 5844 03:22:50,160 --> 03:22:57,320 THE FUTURE TRIALS. 5845 03:22:57,320 --> 03:23:00,160 >> I WANT TO SPEAK TO THAT. 5846 03:23:00,160 --> 03:23:03,640 ONE OF THE THINGS WE'RE TRYING 5847 03:23:03,640 --> 03:23:06,000 TO DO IS WHEN MINDFULNESS IS ONE 5848 03:23:06,000 --> 03:23:07,800 OF THE INTERVENTIONS, WE DON'T 5849 03:23:07,800 --> 03:23:11,400 MENTION IT ANYWHERE IN THE 5850 03:23:11,400 --> 03:23:12,920 CONSENT OR IN THE MARKETING. 5851 03:23:12,920 --> 03:23:14,360 WE TRY TO CALL THEM STRESS 5852 03:23:14,360 --> 03:23:15,760 REDUCTION PROGRAMS OR BEHAVIORAL 5853 03:23:15,760 --> 03:23:17,520 TRAINING PROGRAMS. 5854 03:23:17,520 --> 03:23:23,760 WHAT WE'VE FOUND IS THAT IF WE 5855 03:23:23,760 --> 03:23:25,200 SPECIFICALLY RECRUIT FOR A STUDY 5856 03:23:25,200 --> 03:23:26,520 SAYING MINDFULNESS IS ONE OF THE 5857 03:23:26,520 --> 03:23:29,480 THINGS THAT'S BEING TRAINED, IT 5858 03:23:29,480 --> 03:23:32,680 HAS THE POTENTIAL OF BIASING THE 5859 03:23:32,680 --> 03:23:34,200 STUDY BECAUSE AS HELEN SAID, 5860 03:23:34,200 --> 03:23:35,520 PEOPLE ARE COMING AND THEY MAY 5861 03:23:35,520 --> 03:23:35,960 WANT THAT. 5862 03:23:35,960 --> 03:23:37,240 SO THAT PRIMARY CARE STUDY THAT 5863 03:23:37,240 --> 03:23:38,640 I WAS TELLING YOU ABOUT, WHERE 5864 03:23:38,640 --> 03:23:40,680 THERE WAS A DIFFERENCE BETWEEN 5865 03:23:40,680 --> 03:23:42,480 ONE HOUR AND 8 WEEKS, THAT WAS A 5866 03:23:42,480 --> 03:23:44,360 STUDY WHERE PEOPLE KNEW THAT 5867 03:23:44,360 --> 03:23:48,440 MINDFULNESS WAS WHAT WAS BEING 5868 03:23:48,440 --> 03:23:50,840 OFFERED. 5869 03:23:50,840 --> 03:23:53,000 SO IN THAT CONTEXT, WE SAW A 5870 03:23:53,000 --> 03:23:55,520 CERTAIN AMOUNT OF DROPOUT AND 5871 03:23:55,520 --> 03:23:56,640 DYSPHORIA AMONG THE FOLKS THAT 5872 03:23:56,640 --> 03:23:58,160 DIDN'T GET THE 8 WEEK PROGRAM 5873 03:23:58,160 --> 03:23:59,720 AND ONLY GOT AN HOUR. 5874 03:23:59,720 --> 03:24:01,000 IN OTHER PROGRAMS THAT WE'RE 5875 03:24:01,000 --> 03:24:02,440 RUNNING WHERE WE ARE KEEPING 5876 03:24:02,440 --> 03:24:03,640 IT -- WHERE IT'S A STRESS 5877 03:24:03,640 --> 03:24:07,240 PROGRAM OR RESILIENCE PROGRAM, I 5878 03:24:07,240 --> 03:24:09,440 THINK OFTEN PEOPLE SEEM -- WHEN 5879 03:24:09,440 --> 03:24:11,400 THEY GET RANDOMIZED TO A 5880 03:24:11,400 --> 03:24:12,960 MINDFULNESS CONDITION OF EIGHT 5881 03:24:12,960 --> 03:24:16,360 WEEKS AND TWO HOURS A WEEK, SOME 5882 03:24:16,360 --> 03:24:19,440 PEOPLE KIND OF FEEL OVERWHELMED, 5883 03:24:19,440 --> 03:24:21,280 I THINK, BY THE IDEA OF IT. 5884 03:24:21,280 --> 03:24:23,120 AND DIDN'T FEEL LIKE THEY WANTED 5885 03:24:23,120 --> 03:24:26,200 TO BE DOING THAT KIND OF 5886 03:24:26,200 --> 03:24:26,760 INTENSIVE TURN TOWARDS 5887 03:24:26,760 --> 03:24:29,920 THEMSELVES AND THEIR EXPERIENCE. 5888 03:24:29,920 --> 03:24:31,680 SO JUST SPEAKING TO WHAT HELEN 5889 03:24:31,680 --> 03:24:32,360 SAID, DIFFERENT PEOPLE WANT 5890 03:24:32,360 --> 03:24:35,760 DIFFERENT THINGS, AND A SHORT 5891 03:24:35,760 --> 03:24:36,520 INTERVENTION COULD BE VERY 5892 03:24:36,520 --> 03:24:37,600 APPROPRIATE IF THAT'S WHAT 5893 03:24:37,600 --> 03:24:38,720 SOMEBODY WANTS, AND FOR 5894 03:24:38,720 --> 03:24:42,080 DIFFERENT POPULATIONS, AN 5895 03:24:42,080 --> 03:24:42,840 INFORMAL PRACTICE, THERE ARE 5896 03:24:42,840 --> 03:24:45,400 SEVERAL STUDIES SHOWING THAT -- 5897 03:24:45,400 --> 03:24:47,440 ESPECIALLY WITH ADDICTION, 5898 03:24:47,440 --> 03:24:48,760 WHERE -- THAT THE INFORMAL 5899 03:24:48,760 --> 03:24:50,640 PRACTICE SEEMS TO BE CORRELATING 5900 03:24:50,640 --> 03:24:53,400 WITH OUTCOMES, WHEREAS OTHER 5901 03:24:53,400 --> 03:24:56,240 POPULATIONS, THE LONGER -- THE 5902 03:24:56,240 --> 03:24:57,800 LARGER DOSE OF FOR MALPRACTICE 5903 03:24:57,800 --> 03:24:59,720 MIGHT BE WHAT CORRELATES. 5904 03:24:59,720 --> 03:25:01,800 SO THAT MAY BE ALSO DIFFERENT 5905 03:25:01,800 --> 03:25:02,920 PEOPLE AND DIFFERENT POPULATIONS 5906 03:25:02,920 --> 03:25:07,160 MAY NEED DIFFERENT APPROACHES. 5907 03:25:07,160 --> 03:25:08,800 >> ABSOLUTELY. 5908 03:25:08,800 --> 03:25:10,240 WELL, I JUST WANT TO THANK ALL 5909 03:25:10,240 --> 03:25:12,120 THE SPEAKERS AND HOPEFULLY WE'VE 5910 03:25:12,120 --> 03:25:18,680 GIVEN YOU AS COUNCIL AN IDEA OF 5911 03:25:18,680 --> 03:25:19,880 SORT OF DIFFERENT KINDS OF 5912 03:25:19,880 --> 03:25:21,320 STUDIES CAN BE IMPACTFUL FOR 5913 03:25:21,320 --> 03:25:21,960 DIFFERENT REASONS. 5914 03:25:21,960 --> 03:25:24,600 THE REALLY IMPORTANT THINGS 5915 03:25:24,600 --> 03:25:26,320 THAT, MIKE, YOU LEARNED IN THE 5916 03:25:26,320 --> 03:25:30,160 FEASIBILITY WORK OF HOW DO WE DO 5917 03:25:30,160 --> 03:25:31,680 THIS, AND WE NEED TO SHIFT THIS 5918 03:25:31,680 --> 03:25:32,920 INTERVENTION AROUND AND TAILOR 5919 03:25:32,920 --> 03:25:35,520 IT, WE NEED TO LOCK THAT DOOR SO 5920 03:25:35,520 --> 03:25:37,160 PEOPLE FEEL SAFE, YOU KNOW, IS 5921 03:25:37,160 --> 03:25:37,920 COMPLETELY DIFFERENT THAN A 5922 03:25:37,920 --> 03:25:39,480 DIFFERENT POPULATION THAT SAYS 5923 03:25:39,480 --> 03:25:40,760 NEVER LOCK THE DOOR, I NEED TO 5924 03:25:40,760 --> 03:25:44,840 BE ABLE TO GET OUT. 5925 03:25:44,840 --> 03:25:46,600 AND SORT OF CUSTOMIZING THAT IS 5926 03:25:46,600 --> 03:25:47,880 SO IMPORTANT AND HOW WHAT YOU'RE 5927 03:25:47,880 --> 03:25:50,800 LEARNING HAS INFORMED AND WILL 5928 03:25:50,800 --> 03:25:57,120 HELP YOU DESIGN THAT FUTURE 5929 03:25:57,120 --> 03:25:57,960 TRIAL, AND THEN THE IMPORTANCE 5930 03:25:57,960 --> 03:26:00,080 OF DOING THOSE EFFICACY TESTS 5931 03:26:00,080 --> 03:26:01,920 YOU'RE DOING, ZEV, AND ACTUALLY 5932 03:26:01,920 --> 03:26:02,920 UNDERSTANDING WHAT'S THE IMPACT 5933 03:26:02,920 --> 03:26:04,440 AND THE DIFFERENTIAL IMPACT OF 5934 03:26:04,440 --> 03:26:06,720 DIFFERENT KINDS OF PROGRAMS, 5935 03:26:06,720 --> 03:26:08,280 ABSOLUTELY WILL SET US IN, HELP 5936 03:26:08,280 --> 03:26:09,560 TO INFORM POLICY DECISIONS AND 5937 03:26:09,560 --> 03:26:13,400 WHAT KINDS OF PROGRAMS DIFFERENT 5938 03:26:13,400 --> 03:26:15,520 PAYORS WILL MAKE AVAILABLE, IS A 5939 03:26:15,520 --> 03:26:17,160 COMPLETELY ASYNCHRONOUS CBT 5940 03:26:17,160 --> 03:26:18,000 PROGRAM, SOMETHING THAT WORKS 5941 03:26:18,000 --> 03:26:20,640 JUST AS WELL AS AN IN-PERSON 5942 03:26:20,640 --> 03:26:26,160 DELIVERED SORT OF MBSR TYPE OF 5943 03:26:26,160 --> 03:26:27,040 PROGRAM THAT'S DONE VIRTUALLY. 5944 03:26:27,040 --> 03:26:28,440 THOSE QUESTIONS ARE REALLY 5945 03:26:28,440 --> 03:26:32,360 IMPORTANT TO PAYORS, AND WHO 5946 03:26:32,360 --> 03:26:33,600 NEEDS WHAT INTERVENTION, I THINK 5947 03:26:33,600 --> 03:26:35,040 ARE SOME REALLY INTERESTING 5948 03:26:35,040 --> 03:26:36,440 FUTURE QUESTIONS THAT WE CAN 5949 03:26:36,440 --> 03:26:39,080 LOOK AT. 5950 03:26:39,080 --> 03:26:40,720 AND I THINK, JUDY, YOU'RE DOING 5951 03:26:40,720 --> 03:26:42,720 ALL THIS PREIMPLEMENTATION WORK 5952 03:26:42,720 --> 03:26:44,560 TO FIGURE OUT HOW DO WE MAKE 5953 03:26:44,560 --> 03:26:47,960 SURE THAT THIS PROGRAM WE KNOW 5954 03:26:47,960 --> 03:26:49,280 WORKS IN ONE SETTING, WILL IT 5955 03:26:49,280 --> 03:26:50,720 WORK FOR THIS PARTICULAR 5956 03:26:50,720 --> 03:26:52,000 POPULATION, AND MAKE IT 5957 03:26:52,000 --> 03:26:53,120 SUSTAINABLE, MAKE IT SOMETHING 5958 03:26:53,120 --> 03:26:54,560 THAT COULD BE SCALED TO 5959 03:26:54,560 --> 03:26:59,360 DIFFERENT PLACES AND SO IT'S NOT 5960 03:26:59,360 --> 03:27:01,080 JUST THE EFFICACY STUDY THAT CAN 5961 03:27:01,080 --> 03:27:01,640 HAVE IMPACT. 5962 03:27:01,640 --> 03:27:02,960 IT'S ALL OF THESE DIFFERENT 5963 03:27:02,960 --> 03:27:05,400 STUDIES THAT CAN BE IMPACTFUL 5964 03:27:05,400 --> 03:27:07,040 AND I THINK THOUGHTFUL DESIGN IN 5965 03:27:07,040 --> 03:27:08,920 THESE STUDIES AND THINKING 5966 03:27:08,920 --> 03:27:10,440 THROUGH HOW WAS IT -- WHAT WILL 5967 03:27:10,440 --> 03:27:12,400 I LEARN FROM THE STUDY AND WHERE 5968 03:27:12,400 --> 03:27:13,720 WILL IT TAKE ME NEXT AND WHAT 5969 03:27:13,720 --> 03:27:15,440 WILL BE THE NEXT STEP AFTER 5970 03:27:15,440 --> 03:27:18,560 THAT, THAT'S OFTEN THE ADVICE 5971 03:27:18,560 --> 03:27:20,520 I'M GIVEN TO ALL OF YOU AS 5972 03:27:20,520 --> 03:27:21,440 APPLICANTS, IS THINKING THROUGH, 5973 03:27:21,440 --> 03:27:23,160 YOU KNOW, DESCRIBING YOUR STUDY 5974 03:27:23,160 --> 03:27:26,320 FOR THE REVIEWERS IS NOT ONLY 5975 03:27:26,320 --> 03:27:27,400 WHAT AM I GOING TO DO BUT WHAT 5976 03:27:27,400 --> 03:27:28,840 WILL I LEARN AND HOW WILL IT 5977 03:27:28,840 --> 03:27:31,680 INFORM WHAT I WOULD DO NEXT. 5978 03:27:31,680 --> 03:27:33,240 AND THAT IS REALLY, REALLY 5979 03:27:33,240 --> 03:27:35,760 HELPFUL IN PUTTING TOGETHER 5980 03:27:35,760 --> 03:27:37,040 COMPELLING APPLICATIONS AND FOR 5981 03:27:37,040 --> 03:27:41,320 US AS FUNDERS, COMPELLING 5982 03:27:41,320 --> 03:27:42,640 APPLICATIONS WHERE WE CAN SEE 5983 03:27:42,640 --> 03:27:43,960 WHERE THE SCIENCE IS GOING TO 5984 03:27:43,960 --> 03:27:44,680 LEAD. 5985 03:27:44,680 --> 03:27:49,640 SO EMILY, I DON'T KNOW IF, R 5986 03:27:49,640 --> 03:27:51,200 HELENE, IF YOU HAVE ANY CLOSING 5987 03:27:51,200 --> 03:27:52,360 COMMENTS AS WE WRAP UP. 5988 03:27:52,360 --> 03:27:54,560 >> I WOULD JUST SAY THE SESSION 5989 03:27:54,560 --> 03:27:55,640 REALLY MET OUR OBJECTIVE MORE 5990 03:27:55,640 --> 03:27:56,560 THAN WE EXPECTED. 5991 03:27:56,560 --> 03:28:00,920 THANK YOU SO MUCH FOR THE 5992 03:28:00,920 --> 03:28:01,920 WONDERFUL DISCUSSION, AND I'M 5993 03:28:01,920 --> 03:28:03,000 SURE WE WILL FOLLOW UP WITH ALL 5994 03:28:03,000 --> 03:28:03,640 OF YOU. 5995 03:28:03,640 --> 03:28:12,680 THANK YOU. 5996 03:28:12,680 --> 03:28:13,640 >> OKAY. 5997 03:28:13,640 --> 03:28:15,160 WE'RE GOING TO MOVE ON TO THE 5998 03:28:15,160 --> 03:28:16,040 LAST FORMAL PART OF THE OPEN 5999 03:28:16,040 --> 03:28:19,320 SESSION OF COUNCIL, WHICH IS 6000 03:28:19,320 --> 03:28:19,920 THREE CONCEPT CLEARANCES THAT 6001 03:28:19,920 --> 03:28:20,640 WE'RE GOING TO PRESENT. 6002 03:28:20,640 --> 03:28:24,040 I JUST WANT TO REMIND COUNCIL 6003 03:28:24,040 --> 03:28:28,520 THAT CONCEPT CLEARANCES ARE 6004 03:28:28,520 --> 03:28:30,360 SOMETHING THAT PRECEDES THE 6005 03:28:30,360 --> 03:28:32,120 POSSIBILITY OF DEVELOPING 6006 03:28:32,120 --> 03:28:33,440 FUNDING OPPORTUNITY 6007 03:28:33,440 --> 03:28:35,000 ANNOUNCEMENTS, ONE OR MORE, FROM 6008 03:28:35,000 --> 03:28:35,960 A GIVEN CONCEPT CLEARANCE. 6009 03:28:35,960 --> 03:28:37,680 SO WE PRESENT THESE QUITE 6010 03:28:37,680 --> 03:28:38,800 BROADLY, WITHOUT A LOT OF 6011 03:28:38,800 --> 03:28:40,000 SPECIFICS, BUT IT IS REALLY 6012 03:28:40,000 --> 03:28:43,520 ABOUT THE CONCEPT ITSELF, AS 6013 03:28:43,520 --> 03:28:44,160 YOU'LL SEE. 6014 03:28:44,160 --> 03:28:48,320 SO UP FIRST IS DR. ADAM KUSZAK 6015 03:28:48,320 --> 03:28:49,880 FROM THE OFFICE OF DIETARY 6016 03:28:49,880 --> 03:28:51,200 SUPPLEMENTS, AND ADAM, ARE YOU 6017 03:28:51,200 --> 03:28:52,120 READY TO GO? 6018 03:28:52,120 --> 03:28:53,360 >> YES, I AM. 6019 03:28:53,360 --> 03:28:53,960 CAN YOU HEAR ME? 6020 03:28:53,960 --> 03:28:57,120 >> YES, WE CAN HEAR YOU, AND 6021 03:28:57,120 --> 03:28:58,400 KELLY IS GETTING YOUR SLIDES 6022 03:28:58,400 --> 03:28:59,760 READY. 6023 03:28:59,760 --> 03:29:01,040 >> OKAY. 6024 03:29:01,040 --> 03:29:02,680 SO YOU'RE GOING TO ADVANCE THEM, 6025 03:29:02,680 --> 03:29:03,120 KELLY? 6026 03:29:03,120 --> 03:29:04,320 SO ADAM, WHEN YOU'RE READY FOR 6027 03:29:04,320 --> 03:29:05,640 THE NEXT SLIDE, JUST SAY NEXT 6028 03:29:05,640 --> 03:29:07,640 SLIDE, PLEASE. 6029 03:29:07,640 --> 03:29:08,400 >> PERFECT. 6030 03:29:08,400 --> 03:29:09,480 GOOD AFTERNOON, EVERYBODY. 6031 03:29:09,480 --> 03:29:12,680 AS INTRODUCED, EYE ADAM KUSZAK 6032 03:29:12,680 --> 03:29:14,280 FROM THE OFFICE OF DIETARY SUM. 6033 03:29:14,280 --> 03:29:15,960 I WANT TO THANK MY COLLEAGUES AT 6034 03:29:15,960 --> 03:29:17,080 NCCIH FOR THE OPPORTUNITY TO 6035 03:29:17,080 --> 03:29:18,040 SPEAK WITH YOU TODAY. 6036 03:29:18,040 --> 03:29:20,080 AND WITH THIS PRESENTATION, THE 6037 03:29:20,080 --> 03:29:22,720 OFFICE OF DIETARY SUPPLEMENTS IS 6038 03:29:22,720 --> 03:29:24,920 REQUESTING CONCEPT CLEARANCE FOR 6039 03:29:24,920 --> 03:29:26,600 REISSUE ANS OF AN ADMINISTRATIVE 6040 03:29:26,600 --> 03:29:28,200 SUPPLEMENT FUNDING OPPORTUNITY 6041 03:29:28,200 --> 03:29:28,720 ANNOUNCEMENTS. 6042 03:29:28,720 --> 03:29:30,120 AND THIS ADMINISTRATIVE 6043 03:29:30,120 --> 03:29:31,560 SUPPLEMENT FUNDING OPPORTUNITY 6044 03:29:31,560 --> 03:29:34,640 IS FOR FORMAL VALIDATION STUDIES 6045 03:29:34,640 --> 03:29:36,560 OF ANALYTICAL METHODS THAT 6046 03:29:36,560 --> 03:29:38,080 CHARACTERIZE DIETARY SUPPLEMENTS 6047 03:29:38,080 --> 03:29:42,200 AND NATURAL PRODUCTS. 6048 03:29:42,200 --> 03:29:44,680 SORE THE OFFICE OF DIETARY 6049 03:29:44,680 --> 03:29:46,000 SUPPLEMENT AT NIH COORDINATES 6050 03:29:46,000 --> 03:29:48,560 SEVERAL PROGRAMS AND ACTIVITIES 6051 03:29:48,560 --> 03:29:49,960 TO FULFILL ITS MISSION TO 6052 03:29:49,960 --> 03:29:51,280 SUPPORT SCIENTIFIC RESEARCH TO 6053 03:29:51,280 --> 03:29:52,640 STRENGTHEN OUR UNDERSTANDING OF 6054 03:29:52,640 --> 03:29:53,920 THE HEALTH EFFECTS OF DIETARY 6055 03:29:53,920 --> 03:29:55,560 SUPPLEMENTS. 6056 03:29:55,560 --> 03:29:58,640 THIS FOA IS A COMPONENT OF THE 6057 03:29:58,640 --> 03:30:00,800 ANALYTICAL METHODS AND REFERENCE 6058 03:30:00,800 --> 03:30:02,320 MATERIALS PROGRAM WHICH PROMOTES 6059 03:30:02,320 --> 03:30:04,200 RESOURCE DEVELOPMENT FOR 6060 03:30:04,200 --> 03:30:04,960 CHEMICAL ANALYSES FOR NATURAL 6061 03:30:04,960 --> 03:30:06,360 PRODUCTS. 6062 03:30:06,360 --> 03:30:08,560 AS SUCH, THIS FOA TIES TOGETHER 6063 03:30:08,560 --> 03:30:11,320 WITH SHARED STRATEGIC GOALS OF 6064 03:30:11,320 --> 03:30:13,600 NCCIH AND ODS TO ADVANCE 6065 03:30:13,600 --> 03:30:15,480 RESEARCH RIGOR AND FACILITATE 6066 03:30:15,480 --> 03:30:17,120 RELIABLE ANALYTICAL METHODS FOR 6067 03:30:17,120 --> 03:30:24,920 NATURAL PRODUCT RESEARCH. 6068 03:30:24,920 --> 03:30:32,320 NEXT SLIDE, PLEASE. 6069 03:30:32,320 --> 03:30:33,480 I'M SORRY. 6070 03:30:33,480 --> 03:30:35,320 THANK YOU. 6071 03:30:35,320 --> 03:30:36,720 SO FOR A LITTLE BACKGROUND TO 6072 03:30:36,720 --> 03:30:39,480 THE FOA, REPLICABLE 6073 03:30:39,480 --> 03:30:40,760 CHARACTERIZATION OF KEY 6074 03:30:40,760 --> 03:30:41,960 EXPERIMENTAL RESOURCES AND 6075 03:30:41,960 --> 03:30:43,400 INTERVENTIONS IS AN IMPORTANT 6076 03:30:43,400 --> 03:30:45,160 COMPONENT OF EXPERIMENTAL RIGOR 6077 03:30:45,160 --> 03:30:47,040 AND REPRODUCIBLE RESEARCH. 6078 03:30:47,040 --> 03:30:49,200 AND ONE OF O DS'S RESPONSES TO 6079 03:30:49,200 --> 03:30:51,280 THIS NEED IS AN INITIATIVE THAT 6080 03:30:51,280 --> 03:30:53,400 SUPPORTS VALIDATION STUDIES ON 6081 03:30:53,400 --> 03:30:55,240 METHODS THAT CHARACTERIZE THE 6082 03:30:55,240 --> 03:30:58,520 COMPLEX CHEMICAL COMPOSITION OF 6083 03:30:58,520 --> 03:30:59,200 SUPPLEMENTS AND NATURAL 6084 03:30:59,200 --> 03:31:00,280 PRODUCTS. 6085 03:31:00,280 --> 03:31:01,440 THESE FORMAL VALIDATION STUDIES, 6086 03:31:01,440 --> 03:31:03,240 WHAT THEY DO IS THOROUGHLY 6087 03:31:03,240 --> 03:31:05,440 DETERMINE AN ANALYTICAL METHODS 6088 03:31:05,440 --> 03:31:06,960 MEASUREMENT PARAMETERS, SUCH AS 6089 03:31:06,960 --> 03:31:11,000 ITS ACCURACY, PREVISION, 6090 03:31:11,000 --> 03:31:11,720 APPLICABILITY, REPEATABILITY, 6091 03:31:11,720 --> 03:31:12,520 THOSE TYPES OF THINGS. 6092 03:31:12,520 --> 03:31:16,360 AND THAT CAN BE CRITICAL TO 6093 03:31:16,360 --> 03:31:17,920 ASSESS METHODS PERFORMANCE 6094 03:31:17,920 --> 03:31:18,800 PARAMETERS WHEN USING IT TO 6095 03:31:18,800 --> 03:31:20,760 QUANTIFY THE CHEMICAL 6096 03:31:20,760 --> 03:31:23,920 CONSTITUENTS, METABOLITES, OR 6097 03:31:23,920 --> 03:31:24,800 CONTAMINANTS THAT MIGHT BE FOUND 6098 03:31:24,800 --> 03:31:26,000 IN SUPPLEMENTS OR NATURAL 6099 03:31:26,000 --> 03:31:27,640 PRODUCT RESEARCH, INTERVENTIONS 6100 03:31:27,640 --> 03:31:37,680 OR CLINICAL SPECIMENS. 6101 03:31:37,680 --> 03:31:40,120 SO THE FOA'S CORE PURPOSE IS, 6102 03:31:40,120 --> 03:31:43,160 THEREFORE, THE PROMOTION OF 6103 03:31:43,160 --> 03:31:45,040 EXPERIMENTAL REPLICABILITY AND 6104 03:31:45,040 --> 03:31:46,120 COMPARABILITY, THE ADVANCEMENT 6105 03:31:46,120 --> 03:31:48,000 OF TOOLS THAT ENABLE NATURAL 6106 03:31:48,000 --> 03:31:49,960 PRODUCT REAGENT STANDARDIZATION, 6107 03:31:49,960 --> 03:31:52,600 AND ULTIMATELY INCREASED 6108 03:31:52,600 --> 03:31:54,000 RESEARCH REPRODUCIBILITY THAT 6109 03:31:54,000 --> 03:31:55,600 SUPPORTS RESEARCH'S TRANSLATION 6110 03:31:55,600 --> 03:31:56,400 TO CLINICAL TRIAL 6111 03:31:56,400 --> 03:32:01,840 INVESTIGATIONS. 6112 03:32:01,840 --> 03:32:02,800 I'LL BRIEFLY SUMMARIZE HERE SOME 6113 03:32:02,800 --> 03:32:04,240 OF THE HISTORY AND OUTCOMES OF 6114 03:32:04,240 --> 03:32:08,520 THE FOA TO DATE, THE PRIOR 6115 03:32:08,520 --> 03:32:08,960 ISSUANCES. 6116 03:32:08,960 --> 03:32:10,280 NCCIH HAS BEEN A STRONG PARTNER 6117 03:32:10,280 --> 03:32:11,600 THROUGHOUT THE HISTORY. 6118 03:32:11,600 --> 03:32:13,040 IMPORTANTLY, ODS IS NOT 6119 03:32:13,040 --> 03:32:15,400 REQUESTING FUNDING CONTRIBUTIONS 6120 03:32:15,400 --> 03:32:17,520 FROM NCCIH OR OUR OTHER IC 6121 03:32:17,520 --> 03:32:18,920 PARTNERS. 6122 03:32:18,920 --> 03:32:21,640 FLEURN THE METHOD VALIDATION IS 6123 03:32:21,640 --> 03:32:23,960 COMPARATIVELY A NICHE AREA FOR 6124 03:32:23,960 --> 03:32:25,480 RESEARCHERS, AND THIS IS A 6125 03:32:25,480 --> 03:32:27,360 SMALLER SCALE FUNDING 6126 03:32:27,360 --> 03:32:28,840 INITIATIVE. 6127 03:32:28,840 --> 03:32:30,400 BUT 12 OF THE 17 TOTAL AWARDS 6128 03:32:30,400 --> 03:32:33,160 HAVE BEEN TO NCCIH-FUNDED 6129 03:32:33,160 --> 03:32:37,720 INVESTIGATORS. 6130 03:32:37,720 --> 03:32:39,840 THREE OF THE METHODS THAT WERE 6131 03:32:39,840 --> 03:32:42,680 UNDERGOING VALIDATION, ACTUALLY 6132 03:32:42,680 --> 03:32:43,560 THAT VALIDATION WAS DONE IN 6133 03:32:43,560 --> 03:32:44,760 DIRECT SUPPORT OF A CLINICAL 6134 03:32:44,760 --> 03:32:46,600 TRIAL, AND THERE HAVE BEEN EIGHT 6135 03:32:46,600 --> 03:32:47,720 FORMAL VALIDATION STUDIES 6136 03:32:47,720 --> 03:32:50,920 PUBLISHED. 6137 03:32:50,920 --> 03:32:52,680 I THINK TWO CLICKS OF THE NEXT, 6138 03:32:52,680 --> 03:32:53,320 ONE MORE, PLEASE. 6139 03:32:53,320 --> 03:32:54,160 THANK YOU. 6140 03:32:54,160 --> 03:32:57,160 AS I SAID, THE MAJORITY OF 6141 03:32:57,160 --> 03:32:58,360 ADMINISTRATIVE SUPPLEMENT AWARDS 6142 03:32:58,360 --> 03:32:59,560 HAVE BEEN TO NCCIH INVESTIGATORS 6143 03:32:59,560 --> 03:33:01,520 FOR A TOTAL OF JUST OVER A 6144 03:33:01,520 --> 03:33:03,920 MILLION IN FUNDING SO FAR, AND 6145 03:33:03,920 --> 03:33:06,640 THE METHODS THAT WERE SUBJECT TO 6146 03:33:06,640 --> 03:33:07,600 VALIDATION REALLY THEY'VE BEEN 6147 03:33:07,600 --> 03:33:09,440 APPLICABLE TO A MIXTURE OF 6148 03:33:09,440 --> 03:33:11,160 MECHANISTIC AND CLINICAL FOCUSED 6149 03:33:11,160 --> 03:33:12,680 RESEARCH STUDIES. 6150 03:33:12,680 --> 03:33:14,040 ALSO NOTABLE IS THAT A MAJORITY 6151 03:33:14,040 --> 03:33:15,880 OF THE METHODS WERE FOR 6152 03:33:15,880 --> 03:33:17,080 QUANTIFICATION OF NATURAL 6153 03:33:17,080 --> 03:33:18,600 PRODUCT METABOLITES IN 6154 03:33:18,600 --> 03:33:23,880 BIOLOGICAL SAMPLES. 6155 03:33:23,880 --> 03:33:25,320 SHOWN HERE ARE SOME OF THE 6156 03:33:25,320 --> 03:33:27,160 SPECIFIC PUBLICATIONS THAT 6157 03:33:27,160 --> 03:33:29,040 ILLUSTRATE REALLY HOW THIS 6158 03:33:29,040 --> 03:33:29,600 ADMINISTRATIVE SUPPLEMENT 6159 03:33:29,600 --> 03:33:31,440 FUNDING HAS HELPED INVESTIGATORS 6160 03:33:31,440 --> 03:33:33,320 DEMONSTRATE THE PERFORMANCE OF 6161 03:33:33,320 --> 03:33:34,960 THEIR STATE OF THE ART METHODS. 6162 03:33:34,960 --> 03:33:39,200 SO FOR EXAMPLE, THERE'S BIGGER 6163 03:33:39,200 --> 03:33:43,240 CHROMATOGRAPHY MASS SPEC 6164 03:33:43,240 --> 03:33:44,040 QUANTIFICATION UNDER 6165 03:33:44,040 --> 03:33:45,880 INVESTIGATION FOR INTERACTION 6166 03:33:45,880 --> 03:33:48,200 WITH CYTOCHROME 450s, THERE'S 6167 03:33:48,200 --> 03:33:49,840 GAS CHROMATOGRAPHY MASS SPEC 6168 03:33:49,840 --> 03:33:51,600 CHARACTERIZATION OF A COMPLEX 6169 03:33:51,600 --> 03:33:54,200 MIXTURE OF GRAPE SEED FLAVENOLS 6170 03:33:54,200 --> 03:33:56,400 STUDIES IN MODELS OF STRESS 6171 03:33:56,400 --> 03:33:56,720 RESILIENCE. 6172 03:33:56,720 --> 03:33:57,920 THERE ARE OTHER EXAMPLES BUT THE 6173 03:33:57,920 --> 03:33:59,760 POINT I WANT TO MAKE IS THAT THE 6174 03:33:59,760 --> 03:34:01,800 FORMAL METHOD VALIDATION STUDIES 6175 03:34:01,800 --> 03:34:03,600 HERE, THEY HELPED ADD CONFIDENCE 6176 03:34:03,600 --> 03:34:05,360 TO THE BIOMEDICAL RESEARCH ON 6177 03:34:05,360 --> 03:34:07,240 THE LINKS BETWEEN THE DIETARY 6178 03:34:07,240 --> 03:34:09,120 INGREDIENTS, THEIR METABOLITES, 6179 03:34:09,120 --> 03:34:10,600 MECHANISMS OF ACTION, AND 6180 03:34:10,600 --> 03:34:17,320 ULTIMATELY HEALTH OUTCOMES. 6181 03:34:17,320 --> 03:34:19,720 THE LATEST FOA ISSUANCE, THAT 6182 03:34:19,720 --> 03:34:22,320 ACTUALLY ENDED UP BEING TIME 6183 03:34:22,320 --> 03:34:25,080 WISE CONCURRENT WITH THAT PERIOD 6184 03:34:25,080 --> 03:34:27,160 WHERE THE PANDEMIC HAD THE MOST 6185 03:34:27,160 --> 03:34:28,360 SIGNIFICANT NEGATIVE EFFECTS ON 6186 03:34:28,360 --> 03:34:30,760 RESEARCH AT THE LAB BENCH, SO 6187 03:34:30,760 --> 03:34:32,640 WITH CLOSURES AND LIMITED 6188 03:34:32,640 --> 03:34:33,080 OCCUPANCY. 6189 03:34:33,080 --> 03:34:34,800 BUT WE HAVE SEEN INTEREST FROM 6190 03:34:34,800 --> 03:34:35,840 PIs START TO PICK UP AGAIN 6191 03:34:35,840 --> 03:34:39,960 THIS YEAR. 6192 03:34:39,960 --> 03:34:41,920 SO THEREFORE, ODS REMAINS 6193 03:34:41,920 --> 03:34:45,560 COMMITTED TO SUPPORTING THIS 6194 03:34:45,560 --> 03:34:48,600 APPROACH TO ENHANCING RESEARCH 6195 03:34:48,600 --> 03:34:51,440 RIGOR AND ADDRESSING STRATEGIC 6196 03:34:51,440 --> 03:34:52,200 GOALS THAT OVERLAP WITH NCCIH 6197 03:34:52,200 --> 03:34:53,640 AND OTHER PARTNER ICs AND 6198 03:34:53,640 --> 03:34:54,840 WE'RE REQUESTING CONCEPT 6199 03:34:54,840 --> 03:34:56,800 CLEARANCE FOR A REISSUANCE. 6200 03:34:56,800 --> 03:34:59,120 THE REISSUED FOA IS INTENDED TO 6201 03:34:59,120 --> 03:35:02,840 CONTINUE ITS FOCUS AND PURPOSE, 6202 03:35:02,840 --> 03:35:05,000 ALSO LOOKING TO MORE CLEARLY 6203 03:35:05,000 --> 03:35:06,360 DELINEATE CONSIDERATION OF 6204 03:35:06,360 --> 03:35:07,880 METABOLOMICS METHODS AND 6205 03:35:07,880 --> 03:35:10,040 QUALITATIVE APPROACHES FOR 6206 03:35:10,040 --> 03:35:11,560 IDENTIFICATION AND 6207 03:35:11,560 --> 03:35:12,560 AUTHENTICATION OF COMPLEX 6208 03:35:12,560 --> 03:35:15,320 NATURAL PRODUCT PREPARATIONS. 6209 03:35:15,320 --> 03:35:17,040 AGAIN, THERE CONTINUES TO BE NO 6210 03:35:17,040 --> 03:35:19,880 BUDGET REQUEST TO NCCIH OR OTHER 6211 03:35:19,880 --> 03:35:21,840 IC PARTNERS. 6212 03:35:21,840 --> 03:35:23,160 ODS IS COMMITTED TO FUND THE 6213 03:35:23,160 --> 03:35:24,360 TOTAL COST OF THESE 6214 03:35:24,360 --> 03:35:26,240 ADMINISTRATIVE SUPPLEMENTS. 6215 03:35:26,240 --> 03:35:27,320 AND WITH THAT, I WANT TO SAY 6216 03:35:27,320 --> 03:35:28,520 THANK YOU TO THE COUNCIL FOR 6217 03:35:28,520 --> 03:35:29,400 YOUR CONSIDERATION, AND I'M 6218 03:35:29,400 --> 03:35:36,120 HAPPY TO TAKE ANY QUESTIONS. 6219 03:35:36,120 --> 03:35:37,520 >> THANK YOU, DR. KUSZAK. 6220 03:35:37,520 --> 03:35:46,800 ANY QUESTIONS FROM COUNCIL? 6221 03:35:46,800 --> 03:35:47,920 >> THIS WAS GREAT TO SEE. 6222 03:35:47,920 --> 03:35:49,440 AS YOU KNOW, I'VE BENEFITED FROM 6223 03:35:49,440 --> 03:35:51,600 THIS PROGRAM AT THE PAST AND 6224 03:35:51,600 --> 03:35:52,480 REALLY APPRECIATE ALL YOU'RE 6225 03:35:52,480 --> 03:35:53,920 DOING ON THE STANDARDIZATION 6226 03:35:53,920 --> 03:35:54,680 WORK MAKING SURE PEOPLE ARE 6227 03:35:54,680 --> 03:35:56,480 DOING EFFECTIVE STANDARDIZATION. 6228 03:35:56,480 --> 03:35:59,240 I WONDERED IF YOU HAVE ANY 6229 03:35:59,240 --> 03:36:00,680 PARTICULAR FOCUSES MOVING 6230 03:36:00,680 --> 03:36:04,440 FORWARD ON SPECIFIC BOTANICALS 6231 03:36:04,440 --> 03:36:06,000 THAT HAVEN'T BEEN LOOKED AT AS 6232 03:36:06,000 --> 03:36:07,880 MUCH BUT SEEM TO BE IMPORTANT OR 6233 03:36:07,880 --> 03:36:09,120 IF YOU'RE LEAVING THAT ENTIRELY 6234 03:36:09,120 --> 03:36:10,840 UP TO THE INVESTIGATORS TO 6235 03:36:10,840 --> 03:36:12,080 CHOOSE WHAT'S RELEVANT TO THEIR 6236 03:36:12,080 --> 03:36:12,320 STUDIES? 6237 03:36:12,320 --> 03:36:14,360 >> YEAH, THANKS, NADJA, FOR THE 6238 03:36:14,360 --> 03:36:14,640 QUESTION. 6239 03:36:14,640 --> 03:36:16,920 AND THANK YOU, WE'RE MUCH 6240 03:36:16,920 --> 03:36:17,720 APPRECIATIVE OF ALL YOUR WORK IN 6241 03:36:17,720 --> 03:36:21,480 THE AREA. 6242 03:36:21,480 --> 03:36:23,240 THERE IS NOT A FOCUS ON A 6243 03:36:23,240 --> 03:36:26,240 PARTICULAR BOTANICAL WITH THE 6244 03:36:26,240 --> 03:36:26,560 PROGRAM. 6245 03:36:26,560 --> 03:36:28,640 WE WANT TO HAVE THAT BE OPEN TO 6246 03:36:28,640 --> 03:36:32,680 THE INVESTIGATOR INITIATED FOCUS 6247 03:36:32,680 --> 03:36:35,320 AREAS, SO THERE HAVE BEEN, IN 6248 03:36:35,320 --> 03:36:36,480 THE PAST, EXAMPLES OF THINGS 6249 03:36:36,480 --> 03:36:40,440 THAT ARE VERY PROMINENT IN TERMS 6250 03:36:40,440 --> 03:36:41,520 OF USAGE AND THINGS THAT ARE 6251 03:36:41,520 --> 03:36:44,360 MUCH LOWER IN USE. 6252 03:36:44,360 --> 03:36:47,760 SO WE WANT TO KEEP THAT OPEN FOR 6253 03:36:47,760 --> 03:36:48,640 LETTING THE INVESTIGATOR DRIVE 6254 03:36:48,640 --> 03:36:52,360 THE FOCUS. 6255 03:36:52,360 --> 03:36:56,640 >> MAKES SENSE. 6256 03:36:56,640 --> 03:36:57,440 >> ANY OTHER QUESTIONS OR 6257 03:36:57,440 --> 03:37:04,160 COMMENTS FROM COUNCIL? 6258 03:37:04,160 --> 03:37:05,440 SEEING AND HEARING NONE, WE'LL 6259 03:37:05,440 --> 03:37:06,800 GO AHEAD AND VOTE ON THE CONCEPT 6260 03:37:06,800 --> 03:37:08,040 CLEARANCE. 6261 03:37:08,040 --> 03:37:09,720 YOU'LL SEE IT ON YOUR SCREEN 6262 03:37:09,720 --> 03:37:10,360 MOMENTARILY. 6263 03:37:10,360 --> 03:37:11,560 A POLL QUESTION ASKING YOU TO 6264 03:37:11,560 --> 03:37:11,800 VOTE. 6265 03:37:11,800 --> 03:37:13,320 IF YOU VOTE YES, YOU'RE IN 6266 03:37:13,320 --> 03:37:14,440 CONCURRENCE WITH THE CONCEPT 6267 03:37:14,440 --> 03:37:15,320 CLEARANCE. 6268 03:37:15,320 --> 03:37:17,320 IF NO, THEN UROPOSING IT AND YOU 6269 03:37:17,320 --> 03:37:20,240 CAN ABSTAIN. 6270 03:37:20,240 --> 03:37:21,320 COUNSELING MEMBERS WHO ARE 6271 03:37:21,320 --> 03:37:31,200 ELIGIBLE TO VOTE WILL DO SO NOW. 6272 03:37:31,200 --> 03:37:35,840 AND WE HAVE UNANIMOUS VOTE FOR 6273 03:37:35,840 --> 03:37:37,000 IN FAVOR OF THIS CONCEPT 6274 03:37:37,000 --> 03:37:37,240 CLEARANCE. 6275 03:37:37,240 --> 03:37:38,080 THANK YOU VERY MUCH. 6276 03:37:38,080 --> 03:37:38,400 DR. KUSZAK. 6277 03:37:38,400 --> 03:37:41,480 THANK YOU VERY MUCH. 6278 03:37:41,480 --> 03:37:41,760 FOR YOUR 6279 03:37:41,760 --> 03:37:42,080 PRESENTATION. 6280 03:37:42,080 --> 03:37:42,440 >> THANK YOU. 6281 03:37:42,440 --> 03:37:43,360 THANK YOU, EVERYONE. 6282 03:37:43,360 --> 03:37:43,880 HAVE A GOOD DAY. 6283 03:37:43,880 --> 03:37:46,320 >> THANK YOU. 6284 03:37:46,320 --> 03:37:47,720 WE'LL NOW MOVE TO THE SECOND 6285 03:37:47,720 --> 03:37:48,360 CONCEPT CLEARANCE, WHICH IS 6286 03:37:48,360 --> 03:37:50,800 GOING TO BE PRESENTED BY 6287 03:37:50,800 --> 03:37:52,680 DR. INNA BELFER ON RESEARCH 6288 03:37:52,680 --> 03:37:54,720 NETWORKS TO PROMOTE INNOVATIVE 6289 03:37:54,720 --> 03:37:56,040 MECHANISTIC AND TRANSLATIONAL 6290 03:37:56,040 --> 03:37:58,280 STUDIES OF SICKLE CELL DISEASE 6291 03:37:58,280 --> 03:38:01,960 PAIN. 6292 03:38:01,960 --> 03:38:02,240 DR. BELFER? 6293 03:38:02,240 --> 03:38:04,040 >> THANK YOU, PARTAP. 6294 03:38:04,040 --> 03:38:05,480 GOOD AFTERNOON, EVERYONE. 6295 03:38:05,480 --> 03:38:07,240 TODAY I'M VERY EXCITED TO TELL 6296 03:38:07,240 --> 03:38:14,160 YOU ABOUT THIS NEW INITIATIVE ON 6297 03:38:14,160 --> 03:38:15,400 INNOVATIVE NETWORKS TO PROMOTE 6298 03:38:15,400 --> 03:38:17,680 BASIC AND TRANSLATIONAL RESEARCH 6299 03:38:17,680 --> 03:38:19,440 FOR SICKLE CELL DISEASE. 6300 03:38:19,440 --> 03:38:21,520 SO WHAT IS THE SICKLE CELL 6301 03:38:21,520 --> 03:38:22,200 DISEASE PAIN? 6302 03:38:22,200 --> 03:38:24,160 JUST TO REMIND THAT SICKLE CELL 6303 03:38:24,160 --> 03:38:29,840 DISEASE IS AN UNDERSTUDIED 6304 03:38:29,840 --> 03:38:33,040 LIFELONG DISEASE -- MINORITY 6305 03:38:33,040 --> 03:38:33,720 POPULATIONS IN THE UNITED 6306 03:38:33,720 --> 03:38:34,000 STATES. 6307 03:38:34,000 --> 03:38:36,800 THERE IS ABOUT 100,000 OF 6308 03:38:36,800 --> 03:38:39,240 AFRICAN AMERICANS AND HISPANICS 6309 03:38:39,240 --> 03:38:40,920 AFFECTED BY SICKLE CELL DISEASE. 6310 03:38:40,920 --> 03:38:43,320 PAIN IS THE MOST COMMON CLINICAL 6311 03:38:43,320 --> 03:38:44,760 COMPLICATION OF SICKLE CELL 6312 03:38:44,760 --> 03:38:45,160 DISEASE. 6313 03:38:45,160 --> 03:38:47,280 IT IS CHARACTERIZED BY SEVERE 6314 03:38:47,280 --> 03:38:52,320 ACUTE PAIN EPISODES, ALSO -- 6315 03:38:52,320 --> 03:38:54,200 PAIN, CHRONIC -- PAIN, IT SPANS 6316 03:38:54,200 --> 03:38:58,440 FROM CHILDHOOD TO ADULTHOOD AND 6317 03:38:58,440 --> 03:39:00,000 EVEN AFTER -- FOR SICKLE CELL 6318 03:39:00,000 --> 03:39:00,880 DISEASE. 6319 03:39:00,880 --> 03:39:02,280 SEVERE CHRONIC PAIN CONTINUES IN 6320 03:39:02,280 --> 03:39:07,560 ABOUT 40% OF INDIVIDUALS. 6321 03:39:07,560 --> 03:39:10,920 IT HAS -- IN INDIVIDUALS WITH 6322 03:39:10,920 --> 03:39:12,800 SICKLE CELL DISEASE, HIGH RATE 6323 03:39:12,800 --> 03:39:15,200 OF HOSPITALIZATIONS AND MISSED 6324 03:39:15,200 --> 03:39:16,720 SCHOOL AND WORK DAYS AND POOR 6325 03:39:16,720 --> 03:39:19,040 FUNCTIONAL AND PSYCHOSOCIAL 6326 03:39:19,040 --> 03:39:21,240 OUTCOMES, AS WELL AS INCREASED 6327 03:39:21,240 --> 03:39:22,520 RATE OF MORTALITY. 6328 03:39:22,520 --> 03:39:26,920 THE MANAGEMENT OF SICKLE CELL 6329 03:39:26,920 --> 03:39:27,960 DISEASE PAIN IS COMPLEX AND 6330 03:39:27,960 --> 03:39:30,160 OFTEN DOESN'T ADDRESS MULTIPLE 6331 03:39:30,160 --> 03:39:34,240 COMORBIDITIES SUCH AS ANXIETY, 6332 03:39:34,240 --> 03:39:35,960 STRESS -- AND ORGAN DAMAGE, AND 6333 03:39:35,960 --> 03:39:37,040 ADDED COMPLICATIONS OF THE 6334 03:39:37,040 --> 03:39:39,720 SICKLE CELL DISEASE. 6335 03:39:39,720 --> 03:39:41,240 TO BETTER UNDERSTAND CURRENT 6336 03:39:41,240 --> 03:39:44,400 STATUS AND POTENTIAL FUTURE 6337 03:39:44,400 --> 03:39:45,760 DIRECTION OF SICKLE CELL DISEASE 6338 03:39:45,760 --> 03:39:47,480 PAIN RESEARCH AND PAIN 6339 03:39:47,480 --> 03:39:49,240 MANAGEMENT, NCCIH IN 6340 03:39:49,240 --> 03:39:50,120 COLLABORATION WITH HEART LUNG 6341 03:39:50,120 --> 03:39:57,920 AND BLOOD INSTITUTE, CO-LED -- 6342 03:39:57,920 --> 03:40:01,200 VIRTUAL WORKSHOP LAST YEAR. 6343 03:40:01,200 --> 03:40:04,920 -- SUBJECTS INCLUDING EXPLORING 6344 03:40:04,920 --> 03:40:07,000 CRITICAL GAPS, RESEARCH 6345 03:40:07,000 --> 03:40:08,880 CHALLENGES AND BRAINSTORMING OF 6346 03:40:08,880 --> 03:40:10,680 POTENTIAL SOLUTIONS FOR THIS 6347 03:40:10,680 --> 03:40:15,200 IMROASLY UNDER DID 6348 03:40:15,200 --> 03:40:15,800 GROSSLY UNDERSTUDIED CONDITION 6349 03:40:15,800 --> 03:40:19,600 IN A HIGHLY UNDERSERVED 6350 03:40:19,600 --> 03:40:20,480 POPULATION. 6351 03:40:20,480 --> 03:40:22,040 WE KNOW MUCH ABOUT SICKLE CELL 6352 03:40:22,040 --> 03:40:23,520 DISEASE AS A GENETIC DISEASE 6353 03:40:23,520 --> 03:40:26,640 WITH WELL-KNOWN GENETIC MUTATION 6354 03:40:26,640 --> 03:40:29,680 S BOTH IN VARIOUS LEVELS OF RED 6355 03:40:29,680 --> 03:40:32,360 BLOOD CELL AND CELL SICKLING, 6356 03:40:32,360 --> 03:40:35,480 ESTABLISH UNDERSTANDING OF 6357 03:40:35,480 --> 03:40:37,000 UNDERLYING -- HOWEVER, WE DON'T 6358 03:40:37,000 --> 03:40:40,600 HAVE THIS EXTENT OF KNOWLEDGE 6359 03:40:40,600 --> 03:40:41,800 ABOUT SICKLE CELL DISEASE 6360 03:40:41,800 --> 03:40:44,760 CLEANING MECHANISM OF WHICH IT 6361 03:40:44,760 --> 03:40:48,040 IS STILL POORLY UNDERSTOOD. 6362 03:40:48,040 --> 03:40:49,800 PATIENTS WITH SICKLE CELL 6363 03:40:49,800 --> 03:40:50,920 DISEASE DESCRIBE PAIN OFTEN AS 6364 03:40:50,920 --> 03:40:52,320 DEEP, STABBING, ELECTRICAL, 6365 03:40:52,320 --> 03:40:54,520 THROBBING, BEATING, SPREADING, 6366 03:40:54,520 --> 03:40:58,240 OR LIKE BROKEN GLASS IN THEIR 6367 03:40:58,240 --> 03:40:58,680 VEINS. 6368 03:40:58,680 --> 03:41:00,880 THERE IS ENORMOUS HETEROGENEITY 6369 03:41:00,880 --> 03:41:04,840 IN SICKLE CELL DISEASE PAIN 6370 03:41:04,840 --> 03:41:07,680 POPULATIONS, AS WELL AS WITHIN 6371 03:41:07,680 --> 03:41:08,160 INDIVIDUAL VARIABILITY. 6372 03:41:08,160 --> 03:41:09,840 IN ADDITION PAIN TRAJECTORY IN 6373 03:41:09,840 --> 03:41:11,000 SICKLE CELL DISEASE IS UNIQUE 6374 03:41:11,000 --> 03:41:12,720 AND COMPLICATED. 6375 03:41:12,720 --> 03:41:14,360 IT ALWAYS STARTS WITH ACUTE PAIN 6376 03:41:14,360 --> 03:41:15,960 EPISODES AND THE TYPE OF PAIN 6377 03:41:15,960 --> 03:41:20,760 MAY CHANGE ACROSS LIFESPAN. 6378 03:41:20,760 --> 03:41:23,080 IT'S CHARACTERIZE BID 6379 03:41:23,080 --> 03:41:25,520 MULTIPLE -- PAIN CRISES. 6380 03:41:25,520 --> 03:41:26,200 MOST PATIENTS DEVELOP CHRONIC 6381 03:41:26,200 --> 03:41:28,240 PAIN WITH SUDDEN ACUTE PAIN 6382 03:41:28,240 --> 03:41:31,000 EPISODES AND -- CRISIS ON TOP OF 6383 03:41:31,000 --> 03:41:31,720 CHRONIC PERSIST AT THE PRESENT 6384 03:41:31,720 --> 03:41:36,800 TIME PAIN. 6385 03:41:36,800 --> 03:41:38,440 ON CLINICAL LEVELS, BOTH ACUTE 6386 03:41:38,440 --> 03:41:39,880 AND CHRONIC IT IS A MULTIORGAN 6387 03:41:39,880 --> 03:41:40,760 PROBLEM. 6388 03:41:40,760 --> 03:41:42,160 DUE TO OR DPAN DAMAGE CAUSED BY 6389 03:41:42,160 --> 03:41:43,720 SICKLE CELL DISEASE, MANY 6390 03:41:43,720 --> 03:41:46,960 PATIENTS REPORT ACUTE PAIN IN 6391 03:41:46,960 --> 03:41:49,280 THEIR LIVER, SPLEEN, KIDNEY, 6392 03:41:49,280 --> 03:41:53,640 INTESTINE, CHEST, -- AND GENERAL 6393 03:41:53,640 --> 03:41:53,960 TELLS. 6394 03:41:53,960 --> 03:41:57,240 ALSO THEY HAVE SEVERE HEADACHES 6395 03:41:57,240 --> 03:42:00,120 AND -- PAIN DUE TO THE STROKE, 6396 03:42:00,120 --> 03:42:04,400 ACUTE PAIN EPISODES -- 6397 03:42:04,400 --> 03:42:07,560 VASOOCCLUSIVE CRIES I, BONY 6398 03:42:07,560 --> 03:42:09,520 INFARCTION AND MULTIORGAN 6399 03:42:09,520 --> 03:42:10,400 FAILURE. 6400 03:42:10,400 --> 03:42:12,360 AVASCULAR NECROSIS AND BONY 6401 03:42:12,360 --> 03:42:13,120 INFARCTION. 6402 03:42:13,120 --> 03:42:16,200 RECENTLY, SEVERAL STUDIES 6403 03:42:16,200 --> 03:42:17,200 POINTED MUSCULOSKELETAL PAIN IN 6404 03:42:17,200 --> 03:42:18,280 PATIENTS WITH SICKLE CELL 6405 03:42:18,280 --> 03:42:18,920 DISEASE. 6406 03:42:18,920 --> 03:42:21,160 THIS PAIN IS BELIEVED TO REFLECT 6407 03:42:21,160 --> 03:42:25,160 ACUTE AND CHRONIC INJURIES TO -- 6408 03:42:25,160 --> 03:42:25,840 AND BONES. 6409 03:42:25,840 --> 03:42:28,960 ONE OF THE BIGGEST PROBLEMS 6410 03:42:28,960 --> 03:42:30,640 DISCUSSED AT THE WORKSHOP IS 6411 03:42:30,640 --> 03:42:32,360 THAT CLINICAL STATUS OF ORGAN 6412 03:42:32,360 --> 03:42:38,040 DAMAGE IN SICKLE CELL DISEASE DO 6413 03:42:38,040 --> 03:42:40,240 NOT -- AND MOST ANIMAL IS IT DUS 6414 03:42:40,240 --> 03:42:43,720 OF SICKLE CELL PAIN FOCUS ON 6415 03:42:43,720 --> 03:42:45,680 SKIN, NOT ORGAN IMPACTED IN 6416 03:42:45,680 --> 03:42:47,720 SICKLE CELL DISEASE PATIENTS. 6417 03:42:47,720 --> 03:42:50,080 SO FOR EXAMPLE -- ON MUSCLE 6418 03:42:50,080 --> 03:42:52,080 ACTIVATION CAUSES SICKLE CELL 6419 03:42:52,080 --> 03:42:56,360 DISEASE PAIN -- THAT IS FOCUSING 6420 03:42:56,360 --> 03:43:02,400 ON SENSITIZATION OF -- IN SKIN 6421 03:43:02,400 --> 03:43:04,640 OF -- INTERVENTION STUDY OF THE 6422 03:43:04,640 --> 03:43:07,720 SICKLE CELL MICE -- WERE ALSO 6423 03:43:07,720 --> 03:43:11,440 DONE IN SKIN. 6424 03:43:11,440 --> 03:43:12,680 -- INCLUDE LIMITED 6425 03:43:12,680 --> 03:43:14,520 OPPORTUNITIES TO INTEGRATE 6426 03:43:14,520 --> 03:43:17,800 RESEARCH ACROSS MULTIPLE 6427 03:43:17,800 --> 03:43:19,440 DISCIPLINES, OPPORTUNITIES TO 6428 03:43:19,440 --> 03:43:22,840 CONNECT SICKLE CELL DISEASE 6429 03:43:22,840 --> 03:43:25,040 PAIN -- ACCESS FROM OTHER PAIN 6430 03:43:25,040 --> 03:43:26,000 FIELDS. 6431 03:43:26,000 --> 03:43:28,120 -- DISSEMINATION OF KNOWLEDGE 6432 03:43:28,120 --> 03:43:31,160 ON SICKLE CELL DISEASE RESOURCES 6433 03:43:31,160 --> 03:43:33,440 AND BETWEEN -- CLINICIANS AND 6434 03:43:33,440 --> 03:43:35,680 PATIENTS, DIVERSION IT AND 6435 03:43:35,680 --> 03:43:38,160 INCLUSION OF 6436 03:43:38,160 --> 03:43:38,800 UNDERREPRESENTED --. 6437 03:43:38,800 --> 03:43:40,880 TO OVERCOME THESE FAILURES -- 6438 03:43:40,880 --> 03:43:42,800 DEVELOPMENT OF THREE SUCH 6439 03:43:42,800 --> 03:43:43,840 NETWORKS WITH THE FOLLOWING 6440 03:43:43,840 --> 03:43:44,440 OBJECTIVES. 6441 03:43:44,440 --> 03:43:46,200 ONE OBJECTIVE IS TO DEVELOP 6442 03:43:46,200 --> 03:43:49,680 FRAMEWORK TO ENABLE 6443 03:43:49,680 --> 03:43:50,800 TRANSLATIONAL AND -- STUDIES. 6444 03:43:50,800 --> 03:43:53,520 ALSO TO SUPPORT NOVEL TECHNOLOGY 6445 03:43:53,520 --> 03:43:57,240 SUCH AS HUMANIZE ANIMAL MODELS, 6446 03:43:57,240 --> 03:44:00,680 NOVEL MUSCLE BONE JOINT -- PAIN 6447 03:44:00,680 --> 03:44:03,600 MODEL, MECHANISM-BASED PAIN 6448 03:44:03,600 --> 03:44:06,240 PHENOTYPING, ACCESS TO -- SUCH 6449 03:44:06,240 --> 03:44:09,760 AS DRGs, LARGE OR MIXED 6450 03:44:09,760 --> 03:44:11,240 MICROBIOME AND IMAGING STUDY 6451 03:44:11,240 --> 03:44:12,920 WITH LONGITUDINAL DESIGN TO 6452 03:44:12,920 --> 03:44:13,800 STUDY DEVELOPMENT AND 6453 03:44:13,800 --> 03:44:16,720 PROGRESSION OF PAIN. 6454 03:44:16,720 --> 03:44:18,160 THESE NETWORKS WILL ALSO SUPPORT 6455 03:44:18,160 --> 03:44:20,320 THE DEVELOPMENT OF INTERVENTIONS 6456 03:44:20,320 --> 03:44:22,640 SUCH AS NON-ADDICTIVE 6457 03:44:22,640 --> 03:44:24,600 PHARMACOLOGICAL THERAPIES, 6458 03:44:24,600 --> 03:44:26,920 COMPLEMENTARY INTERVENTIONS 6459 03:44:26,920 --> 03:44:27,960 AND -- BECAUSE SICKLE CELL 6460 03:44:27,960 --> 03:44:31,800 DISEASE IS DEFINITELY A -- 6461 03:44:31,800 --> 03:44:33,160 FUNCTION PROBLEM. 6462 03:44:33,160 --> 03:44:34,960 ALSO THESE NETWORKS WILL BRING 6463 03:44:34,960 --> 03:44:36,960 TOGETHER PEOPLE OF DIFFERENT 6464 03:44:36,960 --> 03:44:38,840 EXPERTISE SUCH AS HEMATOLOGISTS, 6465 03:44:38,840 --> 03:44:42,880 ORGAN BIOLOGISTS, PAIN EXPERTS, 6466 03:44:42,880 --> 03:44:44,640 NEUROSCIENTISTS, PSYCHOLOGISTS, 6467 03:44:44,640 --> 03:44:47,200 GENETICISTS, MICRO BIOLOGISTS, 6468 03:44:47,200 --> 03:44:48,720 BEHAVIORAL SCIENTISTS AND 6469 03:44:48,720 --> 03:44:52,800 CLINICIANS. 6470 03:44:52,800 --> 03:44:54,080 SPECIFICALLY, THE INITIATIVE 6471 03:44:54,080 --> 03:44:58,480 WILL ENCOURAGE THOSE GROUPS TO 6472 03:44:58,480 --> 03:44:59,600 GET TOGETHER FROM VARIOUS 6473 03:44:59,600 --> 03:45:03,480 DISPLIPS AND 6474 03:45:03,480 --> 03:45:06,240 DISCIPLINES AND THEY WILL 6475 03:45:06,240 --> 03:45:07,560 DEVELOP THE PAIN RESEARCH 6476 03:45:07,560 --> 03:45:07,960 NETWORKS. 6477 03:45:07,960 --> 03:45:09,400 THIS WILL INVOLVE TRAINING SUCH 6478 03:45:09,400 --> 03:45:15,200 AS INTENSIVE WORKSHOPS AND 6479 03:45:15,200 --> 03:45:17,120 SUMMER INSTITUTES OR VISITING 6480 03:45:17,120 --> 03:45:18,480 SCHOLAR PROGRAMS. 6481 03:45:18,480 --> 03:45:20,720 MEETING AND CONFERENCES, ALSO 6482 03:45:20,720 --> 03:45:22,520 SMALL SCALE RESEARCH THAT WOULD 6483 03:45:22,520 --> 03:45:23,440 SUPPORT, ENABLE AND LAY THE 6484 03:45:23,440 --> 03:45:25,640 GROUND WORK FOR POTENTIAL 6485 03:45:25,640 --> 03:45:29,560 TARGETED PROJECTS TO ADDRESS THE 6486 03:45:29,560 --> 03:45:31,520 PRIORITY AREAS SUCH AS POTENTIAL 6487 03:45:31,520 --> 03:45:33,160 THERAPEUTIC TARGETS, REVERSE 6488 03:45:33,160 --> 03:45:34,720 TRANSLATION, BIOMARKERS, 6489 03:45:34,720 --> 03:45:35,800 MULTIMODAL INTERVENTIONS, AND 6490 03:45:35,800 --> 03:45:39,440 WHOLE PERSON HEALTH. 6491 03:45:39,440 --> 03:45:41,760 THIS INITIATIVE IS THE SAME 6492 03:45:41,760 --> 03:45:43,360 APPROACH THAT WAS SUCCESSFUL 6493 03:45:43,360 --> 03:45:46,200 WITH OTHER -- PROGRAMS SUCH AS 6494 03:45:46,200 --> 03:45:50,400 EMOTIONAL WELL-BEING AND FORCE 6495 03:45:50,400 --> 03:45:51,520 BASE MANIPULATION. 6496 03:45:51,520 --> 03:45:53,000 THIS APPROACH WOULD AIM TO BRING 6497 03:45:53,000 --> 03:45:54,440 TOGETHER SCIENTISTS AND 6498 03:45:54,440 --> 03:45:56,640 SPECIALISTS THAT CURRENTLY DO 6499 03:45:56,640 --> 03:46:00,280 NOT COLLABORATE AND THE TOPIC OF 6500 03:46:00,280 --> 03:46:01,520 THE -- JOIN FORCES. 6501 03:46:01,520 --> 03:46:03,840 AS WITH OTHER SIMILAR 6502 03:46:03,840 --> 03:46:04,840 INITIATIVES, WE'D HOPE THAT THIS 6503 03:46:04,840 --> 03:46:07,120 PROGRAM WILL BE SUPPORTED BY OUR 6504 03:46:07,120 --> 03:46:10,200 NIH PARTNERS, INCLUDING HEART 6505 03:46:10,200 --> 03:46:13,040 AND LUNG AND BLOOD INSTITUTE, 6506 03:46:13,040 --> 03:46:14,640 CHILD HEALTH AND DISEASE 6507 03:46:14,640 --> 03:46:16,680 INSTITUTE, NIDA, NATIONAL 6508 03:46:16,680 --> 03:46:18,160 INSTITUTE OF MINORITY HEALTH AND 6509 03:46:18,160 --> 03:46:20,240 HEALTH DISPARITIES AND OTHERS. 6510 03:46:20,240 --> 03:46:23,080 WITH THIS, I THANK YOU FOR YOUR 6511 03:46:23,080 --> 03:46:24,400 ATTENTION AND SEEK YOUR APPROVAL 6512 03:46:24,400 --> 03:46:25,600 AND SUPPORT OF THIS NEW 6513 03:46:25,600 --> 03:46:27,200 INITIATIVE. 6514 03:46:27,200 --> 03:46:27,880 AND HAPPY TO ANSWER ANY 6515 03:46:27,880 --> 03:46:31,400 QUESTIONS. 6516 03:46:31,400 --> 03:46:33,160 >> THANK YOU, DR. BELFER. 6517 03:46:33,160 --> 03:46:34,280 QUESTIONS FROM COUNCIL? 6518 03:46:34,280 --> 03:46:38,720 IF YOU COULD GO BACK TO THE 6519 03:46:38,720 --> 03:46:43,440 "HOLLYWOOD SQUARES" HERE. 6520 03:46:43,440 --> 03:46:49,440 THANK YOU. 6521 03:46:49,440 --> 03:46:59,840 QUESTIONS FROM COUNCIL. 6522 03:47:07,920 --> 03:47:11,600 OKAY. 6523 03:47:11,600 --> 03:47:14,120 >> I THINK MAYBE MORE OF A 6524 03:47:14,120 --> 03:47:17,960 COMMENT RATHER THAN A QUESTION. 6525 03:47:17,960 --> 03:47:18,920 I THINK SICKLE CELL IS SOMETHING 6526 03:47:18,920 --> 03:47:22,000 THAT IS WOEFULLY UNDERSTOOD AND 6527 03:47:22,000 --> 03:47:23,400 WOEFULLY UNDERRESEARCHED. 6528 03:47:23,400 --> 03:47:27,480 AND I THINK GETTING LARGE GROUPS 6529 03:47:27,480 --> 03:47:28,480 OF PEOPLE TOGETHER TO 6530 03:47:28,480 --> 03:47:29,800 COLLABORATE ACROSS MULTIPLE 6531 03:47:29,800 --> 03:47:33,200 DISCIPLINES IS REALLY, REALLY 6532 03:47:33,200 --> 03:47:35,040 GREAT. 6533 03:47:35,040 --> 03:47:36,640 SO I THINK THIS IS A REALLY 6534 03:47:36,640 --> 03:47:37,160 EXCITING PROPOSAL. 6535 03:47:37,160 --> 03:47:38,520 >> THANK YOU, DR. COGHILL. 6536 03:47:38,520 --> 03:47:40,480 OTHER COMMENTS OR QUESTIONS? 6537 03:47:40,480 --> 03:47:43,120 DR. HARRIS? 6538 03:47:43,120 --> 03:47:44,320 >> I WOULD SECOND THAT COMMENT 6539 03:47:44,320 --> 03:47:47,720 FROM DR. COGHILL. 6540 03:47:47,720 --> 03:47:51,720 I'M ALSO WONDERING IF THERE'S A 6541 03:47:51,720 --> 03:47:53,720 WAY TO FACILITATE RECRUITMENT OF 6542 03:47:53,720 --> 03:47:56,400 PATIENTS INTO THESE NETWORKS 6543 03:47:56,400 --> 03:47:58,040 BECAUSE IT'S VERY DIFFICULT FOR 6544 03:47:58,040 --> 03:48:00,120 A SINGLE SITE TO BE ABLE TO 6545 03:48:00,120 --> 03:48:01,640 RECRUIT ENOUGH SICKLE CELL 6546 03:48:01,640 --> 03:48:04,680 PATIENTS TO WARRANT STUDY, SO A 6547 03:48:04,680 --> 03:48:08,120 KEY FACTOR IS GOING TO BE 6548 03:48:08,120 --> 03:48:09,040 RECRUITMENT ACROSS MULTIPLE 6549 03:48:09,040 --> 03:48:10,080 SITES AND I'M WONDERING HOW MUCH 6550 03:48:10,080 --> 03:48:11,480 OF THIS INITIATIVE IS GOING TO 6551 03:48:11,480 --> 03:48:14,560 BE GOING TOWARDS THAT 6552 03:48:14,560 --> 03:48:15,440 SPECIFICALLY. 6553 03:48:15,440 --> 03:48:17,360 >> THE PATIENT ENGAGEMENT WILL 6554 03:48:17,360 --> 03:48:20,320 BE A BIG ASPECT OF THE NETWORKS, 6555 03:48:20,320 --> 03:48:22,920 AND DEFINITELY NEEDS TO BE 6556 03:48:22,920 --> 03:48:24,480 ADDRESSED BY THE GROUPS THAT 6557 03:48:24,480 --> 03:48:25,680 WILL PARTICIPATE IN THIS 6558 03:48:25,680 --> 03:48:28,680 INITIATIVE. 6559 03:48:28,680 --> 03:48:31,160 PATIENT ENGAGEMENT AND THE 6560 03:48:31,160 --> 03:48:34,880 EXPERIENCE WITH WORKING OF THE 6561 03:48:34,880 --> 03:48:37,080 PATIENTS DEVELOP -- THIS IS 6562 03:48:37,080 --> 03:48:38,200 DEFINITELY THE EXPERTISE WE'RE 6563 03:48:38,200 --> 03:48:42,880 LOOKING FOR IN THESE NETWORKS. 6564 03:48:42,880 --> 03:48:43,880 >> DR. COGHILL, DID YOU HAVE 6565 03:48:43,880 --> 03:48:44,920 ANOTHER QUESTION? 6566 03:48:44,920 --> 03:48:50,200 >> YEAH, I'LL JUST SECOND RICK'S 6567 03:48:50,200 --> 03:48:51,760 THOUGHTS ON THAT IS, I THINK 6568 03:48:51,760 --> 03:48:54,480 RESEARCH OPPORTUNITIES FOR 6569 03:48:54,480 --> 03:48:56,120 UNDERREPRESENTED MINORITIES ARE, 6570 03:48:56,120 --> 03:48:57,640 AGAIN, IT IS CHALLENGING TO 6571 03:48:57,640 --> 03:48:59,880 REACH OUT, IT'S CHALLENGING TO 6572 03:48:59,880 --> 03:49:01,400 CONNECT WITH THEM IN AN 6573 03:49:01,400 --> 03:49:02,360 APPROPRIATE WAY AND THEN HAVING 6574 03:49:02,360 --> 03:49:05,560 THAT BAKED INTO THE SYSTEM, I 6575 03:49:05,560 --> 03:49:07,280 THINK IS A REALLY POWERFUL 6576 03:49:07,280 --> 03:49:09,160 FEATURE, SO I'M REALLY GLAD THAT 6577 03:49:09,160 --> 03:49:11,880 THAT'S THERE AS WELL. 6578 03:49:11,880 --> 03:49:14,200 >> THANK YOU, DR. COGHILL. 6579 03:49:14,200 --> 03:49:14,480 DR. SHERMAN? 6580 03:49:14,480 --> 03:49:16,040 >> SO I JUST WANT TO OFFER TWO 6581 03:49:16,040 --> 03:49:17,440 COMMENTS. 6582 03:49:17,440 --> 03:49:20,880 FIRST, I LOVE THE IDEA OF 6583 03:49:20,880 --> 03:49:23,280 BUILDING A NETWORK LIKE THIS FOR 6584 03:49:23,280 --> 03:49:24,680 SUCH A COMPLEX CONDITION AND 6585 03:49:24,680 --> 03:49:26,080 TRYING TO BRING PEOPLE TOGETHER. 6586 03:49:26,080 --> 03:49:30,800 I THINK THAT'S FANTASTIC. 6587 03:49:30,800 --> 03:49:33,480 I ALSO WONDER IF YOU CAN USE 6588 03:49:33,480 --> 03:49:37,960 THIS AS A MODEL FOR OTHER KINDS 6589 03:49:37,960 --> 03:49:41,680 OF CONDITIONS THAT MIGHT REQUIRE 6590 03:49:41,680 --> 03:49:42,680 BRINGING DIFFERENT PEOPLE 6591 03:49:42,680 --> 03:49:44,040 TOGETHER THAT ARE COMPLICATED 6592 03:49:44,040 --> 03:49:49,000 LIKE THIS SO THAT WE CAN REALLY 6593 03:49:49,000 --> 03:49:50,280 FIGURE OUT HOW, AS EFFICIENTLY 6594 03:49:50,280 --> 03:49:56,880 AS POSSIBLE, TO BUILD THE 6595 03:49:56,880 --> 03:49:58,200 NETWORKS FOR THESE KINDS OF 6596 03:49:58,200 --> 03:49:59,480 THINGS, SO I THINK THAT JUST 6597 03:49:59,480 --> 03:50:03,360 MIGHT BE A POTENTIAL ANCILLARY 6598 03:50:03,360 --> 03:50:04,520 CONSEQUENCE IF WE'RE PAYING 6599 03:50:04,520 --> 03:50:06,320 ATTENTION. 6600 03:50:06,320 --> 03:50:09,480 >> THANK YOU, DR. SHERMAN. 6601 03:50:09,480 --> 03:50:11,000 DR. EDWARDS, DID YOU WANT TO 6602 03:50:11,000 --> 03:50:14,400 COMMENT ON DR. SHERMAN'S POINT? 6603 03:50:14,400 --> 03:50:17,360 >> DID YOU CALL ON ME FOR THAT? 6604 03:50:17,360 --> 03:50:19,200 >> YES, I JUST WONDERING IF YOU 6605 03:50:19,200 --> 03:50:20,720 WANTED TO COMMENT ON WHAT 6606 03:50:20,720 --> 03:50:21,280 DR. SHERMAN WAS SAYING. 6607 03:50:21,280 --> 03:50:22,920 >> SURE, I'LL JUST SAY, KAREN, 6608 03:50:22,920 --> 03:50:24,800 WE'VE BEEN REALLY EXPERIMENTING 6609 03:50:24,800 --> 03:50:25,560 WITH THIS MODEL. 6610 03:50:25,560 --> 03:50:28,080 THIS IS GOING TO BE -- IF YOU 6611 03:50:28,080 --> 03:50:30,280 CONCUR, THIS WOULD BE THE THIRD 6612 03:50:30,280 --> 03:50:32,560 SET OF NETWORKS THAT NCCIH WOULD 6613 03:50:32,560 --> 03:50:33,760 BE SPONSORING. 6614 03:50:33,760 --> 03:50:36,280 AS YOU RECALL, WE STARTED OUT 6615 03:50:36,280 --> 03:50:38,560 WITH EMOTIONAL WELL-BEING 6616 03:50:38,560 --> 03:50:41,560 NETWORKS, AND BRINGING TOGETHER 6617 03:50:41,560 --> 03:50:42,840 INVESTIGATORS FROM VARIOUS 6618 03:50:42,840 --> 03:50:44,400 DISCIPLINES TRYING TO UNDERSTAND 6619 03:50:44,400 --> 03:50:47,600 THE MECHANISM OF WELL-BEING. 6620 03:50:47,600 --> 03:50:50,080 AND THEN WE MOVE TO THE FORCE 6621 03:50:50,080 --> 03:50:51,400 BASE MANIPULATION, WHERE WE'RE 6622 03:50:51,400 --> 03:50:52,960 BRINGING TOGETHER 6623 03:50:52,960 --> 03:50:55,440 NEUROSCIENTISTS TO WORK WITH 6624 03:50:55,440 --> 03:50:57,200 INVESTIGATORS THAT WERE IN THE 6625 03:50:57,200 --> 03:50:58,280 MANUAL THERAPY FIELD. 6626 03:50:58,280 --> 03:51:02,560 AND SO WE SEE THIS AS ACTUALLY A 6627 03:51:02,560 --> 03:51:05,080 FAIRLY ECONOMICAL WAY TO JUMP 6628 03:51:05,080 --> 03:51:08,560 START THE FIELD. 6629 03:51:08,560 --> 03:51:13,160 AND THIS PROGRAM THAT RENA IS 6630 03:51:13,160 --> 03:51:14,840 PRESENTED TO YOU IS CONTINUING 6631 03:51:14,840 --> 03:51:15,240 THAT PRACTICE. 6632 03:51:15,240 --> 03:51:16,600 AND I THINK WE'LL HAVE ONE MORE 6633 03:51:16,600 --> 03:51:20,440 LATER ON THIS AFTERNOON AS WELL. 6634 03:51:20,440 --> 03:51:21,840 SO WE ARE REALLY SATISFIED AND 6635 03:51:21,840 --> 03:51:24,480 PLEASED WITH THE PROGRESS THAT 6636 03:51:24,480 --> 03:51:26,320 THE CURRENT NETWORKS ARE DOING, 6637 03:51:26,320 --> 03:51:28,520 AND VERY HOPEFUL THAT THIS IS A 6638 03:51:28,520 --> 03:51:30,360 GOOD MODEL FOR US TO -- 6639 03:51:30,360 --> 03:51:30,920 >> SURE. 6640 03:51:30,920 --> 03:51:32,040 THIS IS A LITTLE BIT DIFFERENT 6641 03:51:32,040 --> 03:51:35,680 BECAUSE IT FOCUSES ON SORT OF 6642 03:51:35,680 --> 03:51:36,800 MORE OF A DISEASE CONDITION 6643 03:51:36,800 --> 03:51:38,280 THAT'S ACTUALLY VERY 6644 03:51:38,280 --> 03:51:40,920 COMPLICATED, SO I THINK THAT WAS 6645 03:51:40,920 --> 03:51:42,320 THE ANGLE I WAS PICKING THIS UP 6646 03:51:42,320 --> 03:51:43,520 FROM, BUT YOUR POINT, OF COURSE, 6647 03:51:43,520 --> 03:51:45,080 IS VERY WELL TAKEN. 6648 03:51:45,080 --> 03:51:48,680 >> THANKS. 6649 03:51:48,680 --> 03:51:50,560 >> DR. MEHLING, I SAW YOU POSTED 6650 03:51:50,560 --> 03:51:51,160 A COMMENT IN THE CHAS. 6651 03:51:51,160 --> 03:51:54,800 DID YOU WANT CHAT. 6652 03:51:54,800 --> 03:51:57,000 DID YOU WANT TO FOLLOW UP ON 6653 03:51:57,000 --> 03:51:57,200 THAT? 6654 03:51:57,200 --> 03:52:00,040 >> I JUST REVIEWED RECENTLY A 6655 03:52:00,040 --> 03:52:02,360 GRANT WHERE I LEARNED THERE IS 6656 03:52:02,360 --> 03:52:03,240 SUPPOSEDLY SOMETHING LIKE A 6657 03:52:03,240 --> 03:52:04,360 CLINICAL RESEARCH NETWORK 6658 03:52:04,360 --> 03:52:09,280 ALREADY FOR SICKLE CELL DISEASE. 6659 03:52:09,280 --> 03:52:11,360 -- INCLUDE NEUROSCIENTISTS BUT 6660 03:52:11,360 --> 03:52:13,000 I THINK THERE IS A NETWORK OF 6661 03:52:13,000 --> 03:52:19,280 CLINICS ALREADY NATIONWIDE. 6662 03:52:19,280 --> 03:52:20,200 >> THANK YOU. 6663 03:52:20,200 --> 03:52:24,080 >> SICKLE CELL DISEASE FOCUSED 6664 03:52:24,080 --> 03:52:24,960 NETWORKS. 6665 03:52:24,960 --> 03:52:26,720 HOWEVER, THEY'RE FOCUSED ON THE 6666 03:52:26,720 --> 03:52:27,920 DIFFERENT ASPECTS. 6667 03:52:27,920 --> 03:52:30,200 THE NETWORKS THAT THIS 6668 03:52:30,200 --> 03:52:32,840 INITIATIVE WOULD SUPPORT WOULD 6669 03:52:32,840 --> 03:52:33,960 HAVE MULTICOMPONENT WHICH WILL 6670 03:52:33,960 --> 03:52:37,240 HAVE A CENTER THAT WOULD 6671 03:52:37,240 --> 03:52:39,640 COORDINATE DIFFERENT CRITICAL -- 6672 03:52:39,640 --> 03:52:41,080 AND DIFFERENT RESEARCH PROCESS 6673 03:52:41,080 --> 03:52:42,840 AND DIFFERENT TRAINING PROGRAMS. 6674 03:52:42,840 --> 03:52:45,240 THESE WOULD BE THE UNIQUE 6675 03:52:45,240 --> 03:52:46,520 COMPONENTS THAT OTHER SICKLE 6676 03:52:46,520 --> 03:52:49,640 CELL DISEASE PROGRAMS THAT ARE 6677 03:52:49,640 --> 03:52:52,760 MORE FOCUSED ON PARTICULAR 6678 03:52:52,760 --> 03:52:54,160 THERAPIES, AND THEY WOULD BE 6679 03:52:54,160 --> 03:52:58,360 MISSING THIS COMPONENT OF CROSS 6680 03:52:58,360 --> 03:53:01,520 DISCIPLINE -- THAT IS ONE OF 6681 03:53:01,520 --> 03:53:06,000 THE -- OF THIS INITIATIVE. 6682 03:53:06,000 --> 03:53:07,440 PRIORITIES OF THIS INITIATIVE. 6683 03:53:07,440 --> 03:53:11,800 >> ANY NICHE QUESTIONS OR 6684 03:53:11,800 --> 03:53:13,160 COMMENTS, ANYTHING TO ADD BEFORE 6685 03:53:13,160 --> 03:53:13,920 WE VOTE? 6686 03:53:13,920 --> 03:53:14,240 OKAY. 6687 03:53:14,240 --> 03:53:15,880 SEEING NO HANDS UP OR HEARING 6688 03:53:15,880 --> 03:53:17,280 ANYTHING, I'D LIKE TO GO AHEAD 6689 03:53:17,280 --> 03:53:18,680 AND LET'S CALL THE VOTE ON THIS. 6690 03:53:18,680 --> 03:53:20,720 YOU'LL SEE ON YOUR SCREENS THE 6691 03:53:20,720 --> 03:53:23,240 USUAL THING, IF YOU'RE VOTING 6692 03:53:23,240 --> 03:53:24,960 YES, YOU'RE FOR APPROVING THE 6693 03:53:24,960 --> 03:53:26,160 CONCEPT CLEARANCE, NO WOULD BE 6694 03:53:26,160 --> 03:53:36,640 FOR NOT, OR YOU MAY ABSTAIN. 6695 03:53:44,400 --> 03:53:51,880 13 IN FAVOR, ONE ABSTENTION. 6696 03:53:51,880 --> 03:53:53,440 THANK YOU VERY MUCH, DR. BELFER. 6697 03:53:53,440 --> 03:53:55,400 FOR THE THIRD CONCEPT FOR TODAY, 6698 03:53:55,400 --> 03:53:58,680 THIRD AND LAST GOING TO BE 6699 03:53:58,680 --> 03:54:00,640 PRESENTED BY DR. WEN CHEN, 6700 03:54:00,640 --> 03:54:06,120 BUILDING CROSS-CUTTING RESEARCH 6701 03:54:06,120 --> 03:54:08,320 NETWORKS TO PROMOTE 6702 03:54:08,320 --> 03:54:09,760 MULTIDISCIPLINARY MECHANISTIC 6703 03:54:09,760 --> 03:54:11,160 STUDIES OF MUSIC AND HEALTH. 6704 03:54:11,160 --> 03:54:12,800 AND IN THIS CASE, WEN, YOU'RE 6705 03:54:12,800 --> 03:54:13,880 GOING TO BE SHARING YOUR SCREEN 6706 03:54:13,880 --> 03:54:18,360 AND PRESENTING YOUR OWN SLIDES. 6707 03:54:18,360 --> 03:54:19,880 >> ARE YOU LOOKING AT THE RIGHT 6708 03:54:19,880 --> 03:54:20,640 SLIDE, I HOPE? 6709 03:54:20,640 --> 03:54:22,440 >> WE GOT THE RIGHT SLIDE BUT 6710 03:54:22,440 --> 03:54:26,600 YOU'VE GOT YOUR -- YOU'RE NOT IN 6711 03:54:26,600 --> 03:54:27,040 PRESENTATION MODE. 6712 03:54:27,040 --> 03:54:27,600 >> OKAY. 6713 03:54:27,600 --> 03:54:36,280 LET ME TRY TO SWAP THE DISPLAY. 6714 03:54:36,280 --> 03:54:37,000 IS THIS CORRECT NOW? 6715 03:54:37,000 --> 03:54:38,280 >> YES, THAT'S PERFECT. 6716 03:54:38,280 --> 03:54:38,600 >> EXCELLENT. 6717 03:54:38,600 --> 03:54:39,560 THANK YOU. 6718 03:54:39,560 --> 03:54:41,960 WELL, GOOD AFTERNOON, EVERYONE. 6719 03:54:41,960 --> 03:54:46,880 AS A FINAL ACT TODAY, I AM THE 6720 03:54:46,880 --> 03:54:47,880 CHIEF OF MECHANISTIC RESEARCH 6721 03:54:47,880 --> 03:54:50,040 BRANCH WITHIN THE DIVISION OF 6722 03:54:50,040 --> 03:54:52,760 EXTRA RESEARCH AT NCCIH. 6723 03:54:52,760 --> 03:54:56,280 TODAY I AM PRESENTING A NOVEL 6724 03:54:56,280 --> 03:54:57,800 CONCEPT RELATED TO BUILDING 6725 03:54:57,800 --> 03:54:59,040 CROSS-CUTTING RESEARCH NETWORKS 6726 03:54:59,040 --> 03:55:00,760 TO PROMOTE MULTIDISCIPLINARY 6727 03:55:00,760 --> 03:55:04,680 MECHANISTIC STUDIES OF MUSIC AND 6728 03:55:04,680 --> 03:55:06,600 HEALTH. 6729 03:55:06,600 --> 03:55:08,640 SO TO BEGIN THIS PRESENTATION, 6730 03:55:08,640 --> 03:55:09,960 I'D LIKE TO HAVE A QUICK 6731 03:55:09,960 --> 03:55:14,200 REFRESHER ON HISTORY OF THIS 6732 03:55:14,200 --> 03:55:17,040 TRANS-NIH THANK MUSIC AND HEH 6733 03:55:17,040 --> 03:55:17,360 INITIATIVES. 6734 03:55:17,360 --> 03:55:18,960 IT STARTED WITH TWO MUSIC 6735 03:55:18,960 --> 03:55:24,520 LOVERS, THE FAMOUS U.S. SOPRANO 6736 03:55:24,520 --> 03:55:31,680 MRS. RENE -- AND OUR BELOVED NIH 6737 03:55:31,680 --> 03:55:32,960 DIRECTOR FRANCIS COLLINS MANY 6738 03:55:32,960 --> 03:55:34,640 YEARS AGO IN A SOCIAL EVENT THAT 6739 03:55:34,640 --> 03:55:36,280 EXPLORED THE IDEA OF MUSIC AND 6740 03:55:36,280 --> 03:55:38,680 MEDICINE TOGETHER. 6741 03:55:38,680 --> 03:55:39,760 THE INITIAL CONVERSATION 6742 03:55:39,760 --> 03:55:42,160 EVENTUALLY LED TO THE FIRST EVER 6743 03:55:42,160 --> 03:55:44,160 NIH WORKSHOP ON MUSIC AND THE 6744 03:55:44,160 --> 03:55:48,200 BRAIN, RESEARCH ACROSS THE 6745 03:55:48,200 --> 03:55:49,640 LIFESPAN, IN JANUARY OF 2017, 6746 03:55:49,640 --> 03:55:53,160 SLIGHTLY OVER FIVE YEARS AGO. 6747 03:55:53,160 --> 03:55:54,800 THE KENNEDY CENTER FOR 6748 03:55:54,800 --> 03:55:55,640 PERFORMING ARTS, NATIONAL 6749 03:55:55,640 --> 03:55:58,960 ENDOWMENT FOR THE ARTS WHICH IS 6750 03:55:58,960 --> 03:56:00,600 PART OF THE DEPARTMENT OF 6751 03:56:00,600 --> 03:56:02,680 EDUCATION AND MUSIC THERAPY 6752 03:56:02,680 --> 03:56:04,000 PROFESSIONAL AND ADVOCACY GROUPS 6753 03:56:04,000 --> 03:56:06,920 TO THE NIH TO DISCUSS BASIC 6754 03:56:06,920 --> 03:56:07,920 MECHANISTIC WAYS THAT MUSIC CAN 6755 03:56:07,920 --> 03:56:10,000 AFFECT THE BRAIN AS WELL AS 6756 03:56:10,000 --> 03:56:15,040 MUSIC AND HEALING. 6757 03:56:15,040 --> 03:56:17,160 THAT WORKSHOP ALSO RESULTED IN A 6758 03:56:17,160 --> 03:56:19,320 LANDMARK REVIEW ARTICLE 6759 03:56:19,320 --> 03:56:21,280 PUBLISHED IN NEURON IN 2018 ON 6760 03:56:21,280 --> 03:56:25,800 MUSIC AND THE BRAIN. 6761 03:56:25,800 --> 03:56:27,440 MOST IMPORTANTLY THIS NEURON 6762 03:56:27,440 --> 03:56:32,680 PAPER SUMMARIZES RESEARCH MUSIC 6763 03:56:32,680 --> 03:56:34,240 IN THE BRAIN SPECIFICALLY IN 6764 03:56:34,240 --> 03:56:36,680 AREAS OF BASIC MECHANISTIC 6765 03:56:36,680 --> 03:56:37,480 RESEARCH, TRANSLATIONAL AND 6766 03:56:37,480 --> 03:56:39,800 CLINICAL RESEARCH METHODS AND 6767 03:56:39,800 --> 03:56:42,960 OUTCOME AS WELL AS CAPACITY 6768 03:56:42,960 --> 03:56:44,160 BUILDING AND INFRASTRUCTURE. 6769 03:56:44,160 --> 03:56:48,120 TO TACKLE THOSE RECOMMENDATIONS, 6770 03:56:48,120 --> 03:56:50,120 NIH IMMEDIATELY FORMED A 6771 03:56:50,120 --> 03:56:52,840 TRANS-NIH WORKING GROUP ON MUSIC 6772 03:56:52,840 --> 03:56:53,600 AND HEALTH. 6773 03:56:53,600 --> 03:56:55,240 THE GROUP FIRST FOCUSED ON THE 6774 03:56:55,240 --> 03:56:58,000 TOP TWO TOPICS FROM THE WORKSHOP 6775 03:56:58,000 --> 03:56:59,960 RECOMMENDATIONS, SUPPORTING 6776 03:56:59,960 --> 03:57:01,320 BASIC MECHANISTIC RESEARCH AS 6777 03:57:01,320 --> 03:57:02,600 WELL AS TRANSLATIONAL AND 6778 03:57:02,600 --> 03:57:05,560 CLINICAL RESEARCH THROUGH A SET 6779 03:57:05,560 --> 03:57:11,080 OF THREE RFAs UTILIZING THE 6780 03:57:11,080 --> 03:57:13,480 R61R33, R21 AND R01 FUNDING 6781 03:57:13,480 --> 03:57:13,800 MECHANISMS. 6782 03:57:13,800 --> 03:57:18,720 A TOTAL OF 15 AWARDS WERE MADE 6783 03:57:18,720 --> 03:57:21,040 PHYSICALLY IN 2019 WITH OVER 6784 03:57:21,040 --> 03:57:23,560 5 MILLION PER YEAR IN AWARDS. 6785 03:57:23,560 --> 03:57:28,240 FOR SOME OF YOU WHO WERE AT 6786 03:57:28,240 --> 03:57:30,120 COUNCIL AT THAT TIME, YOU MAY 6787 03:57:30,120 --> 03:57:32,320 HAVE ACTUALLY REVIEWED THOSE 6788 03:57:32,320 --> 03:57:33,520 CONCEPTS AS WELL AS THE FUNDING 6789 03:57:33,520 --> 03:57:39,520 PLAN FOR THOSE INITIATIVES. 6790 03:57:39,520 --> 03:57:44,040 AND IN FISCAL YEAR 2020, WE 6791 03:57:44,040 --> 03:57:46,880 FOLLOWED UP THE INITIAL RFAs 6792 03:57:46,880 --> 03:57:48,400 WITH ACTUALLY MULTIPLE PROGRAM 6793 03:57:48,400 --> 03:57:50,280 ANNOUNCEMENTS TO CONTINUE OUR 6794 03:57:50,280 --> 03:57:51,560 SUPPORT FOR MUSIC AND HEALTH 6795 03:57:51,560 --> 03:57:55,160 RESEARCH. 6796 03:57:55,160 --> 03:57:59,560 IN 2021, THE WORKING GROUP LED 6797 03:57:59,560 --> 03:58:03,040 BY NCCIH -- ORGANIZED THREE HALF 6798 03:58:03,040 --> 03:58:07,240 DAY WORKSHOPS TO TACKLE THE 6799 03:58:07,240 --> 03:58:08,640 RECOMMENDATIONS ON METHODS AND 6800 03:58:08,640 --> 03:58:09,280 OUTCOMES. 6801 03:58:09,280 --> 03:58:10,600 THE FIRST WORKSHOP LAID THE 6802 03:58:10,600 --> 03:58:12,360 FOUNDATION BY DEFINING THE 6803 03:58:12,360 --> 03:58:13,880 BUILDING BLOCKS OF THE 6804 03:58:13,880 --> 03:58:15,520 MUSIC-BASED INTERVENTIONS. 6805 03:58:15,520 --> 03:58:17,400 THE SECOND WORKSHOP FOCUSED ON 6806 03:58:17,400 --> 03:58:19,800 ASSESSING AND MEASURING TARGET 6807 03:58:19,800 --> 03:58:23,960 ENGAGEMENT, SPECIFICALLY ON 6808 03:58:23,960 --> 03:58:27,560 MECHANISTIC AND -- OUT COME 6809 03:58:27,560 --> 03:58:29,440 MEASURES FOR BRAIN DISORDERS OF 6810 03:58:29,440 --> 03:58:30,960 AGING, AND THE THIRD WORKSHOP 6811 03:58:30,960 --> 03:58:32,480 WORKED ON RELATING TARGET 6812 03:58:32,480 --> 03:58:35,120 ENGAGEMENT TO CLINICAL BENEFITS. 6813 03:58:35,120 --> 03:58:38,480 THE SERIES OF EFFORTS IS 6814 03:58:38,480 --> 03:58:41,000 SUMMARIZED IN THE MANUSCRIPT 6815 03:58:41,000 --> 03:58:46,160 CURRENTLY UNDER CONSIDERATION 6816 03:58:46,160 --> 03:58:47,480 ENTITLED NIH MUSIC-BASED 6817 03:58:47,480 --> 03:58:48,280 INTERVENTIONS TOOLKIT. 6818 03:58:48,280 --> 03:58:52,080 THE ONLY CATEGORY OF THE 2017 6819 03:58:52,080 --> 03:58:52,920 WORKSHOP RECOMMENDATIONS YET TO 6820 03:58:52,920 --> 03:58:55,120 BE ADDRESSED IS THE CAPACITY 6821 03:58:55,120 --> 03:58:58,400 BUILDING AND INFRASTRUCTURE. 6822 03:58:58,400 --> 03:58:59,920 MORE SPECIFICALLY THROUGH 6823 03:58:59,920 --> 03:59:01,040 NETWORKS AND COLLABORATIVE 6824 03:59:01,040 --> 03:59:02,720 STUDIES INVOLVING 6825 03:59:02,720 --> 03:59:04,440 NEUROSCIENTISTS, MUSIC 6826 03:59:04,440 --> 03:59:07,400 THERAPISTS, MUSICIANS, 6827 03:59:07,400 --> 03:59:08,880 BIOMEDICAL, BEHAVIORAL OR SOCIAL 6828 03:59:08,880 --> 03:59:13,440 SIGH TISES 6829 03:59:13,440 --> 03:59:17,240 SCIENTISTS AND -- EVIDENCE-BASED 6830 03:59:17,240 --> 03:59:17,640 BEST PRACTICE. 6831 03:59:17,640 --> 03:59:19,920 AS YOU HEARD FROM DR. BELFER'S 6832 03:59:19,920 --> 03:59:20,480 PRESENTATION AS WELL AS 6833 03:59:20,480 --> 03:59:23,040 DISCUSSION ON A NUMBER OF PRIOR 6834 03:59:23,040 --> 03:59:26,840 MODELS OF RESEARCH NETWORKS, WE 6835 03:59:26,840 --> 03:59:29,760 FELT THAT A COLLECTION OF 6836 03:59:29,760 --> 03:59:33,640 RESEARCH NETWORKS FOCUS ON MUSIC 6837 03:59:33,640 --> 03:59:34,960 AND HEALTH MAY BE THE BEST 6838 03:59:34,960 --> 03:59:38,880 APPROACH TO ADDRESS THE SPECIFIC 6839 03:59:38,880 --> 03:59:42,360 RECOMMENDATION ALIGNED IN THAT 6840 03:59:42,360 --> 03:59:43,920 NEURON PAPER. 6841 03:59:43,920 --> 03:59:45,520 CONCEPTUALLY, WE CAN HAVE EACH 6842 03:59:45,520 --> 03:59:48,320 NETWORK MAY FOCUS ON A SPECIFIC 6843 03:59:48,320 --> 03:59:52,040 CONDITION SUCH AS PAIN OR 6844 03:59:52,040 --> 03:59:54,200 ALZHEIMER'S DISEASE OR STROKE OR 6845 03:59:54,200 --> 03:59:55,720 PARKINSON'S DISEASE OR COULD BE 6846 03:59:55,720 --> 03:59:57,880 EVEN MENTAL HEALTH DISORDERS, 6847 03:59:57,880 --> 04:00:00,440 AND TOGETHER THEY WILL ADDRESS 6848 04:00:00,440 --> 04:00:03,480 SOME COMMON TOPICS RELATED TO 6849 04:00:03,480 --> 04:00:04,800 MUSIC-BASED INTERVENTIONS AS 6850 04:00:04,800 --> 04:00:07,440 WELL, ESPECIALLY REGARDING 6851 04:00:07,440 --> 04:00:09,080 TERMINOLOGIES AND TAXONOMY, FOR 6852 04:00:09,080 --> 04:00:13,000 EXAMPLE. 6853 04:00:13,000 --> 04:00:14,040 THIS RESEARCH NETWORKS CAN 6854 04:00:14,040 --> 04:00:15,360 ACCOMPLISH OBJECTIVES THROUGH 6855 04:00:15,360 --> 04:00:16,880 MEETINGS, WORKSHOPS, CONFERENCES 6856 04:00:16,880 --> 04:00:19,000 BOTH VIRTUAL AND IN PERSON, AS 6857 04:00:19,000 --> 04:00:21,000 WELL AS COLLABORATIVE 6858 04:00:21,000 --> 04:00:22,760 DISCUSSIONS IN EXCHANGE FOR 6859 04:00:22,760 --> 04:00:23,880 VISITING SCIENTIST ARRANGEMENTS 6860 04:00:23,880 --> 04:00:24,640 AS WELL AS TRAINING 6861 04:00:24,640 --> 04:00:27,400 OPPORTUNITIES, FOR EXA FOR . 6862 04:00:27,400 --> 04:00:30,200 THE NETWORKS MAY ALSO FUND PILOT 6863 04:00:30,200 --> 04:00:34,080 RESEARCH PROJECTS THAT WILL FILL 6864 04:00:34,080 --> 04:00:35,480 UNIQUE GAPS IDENTIFIED TO 6865 04:00:35,480 --> 04:00:37,560 PREPARE FOR THE NECESSARY 6866 04:00:37,560 --> 04:00:39,320 PRELIMINARY DATA THAT WILL BE 6867 04:00:39,320 --> 04:00:42,720 HELPFUL TO THE INVESTIGATORS TO 6868 04:00:42,720 --> 04:00:46,400 PREPARE COMPETITIVE NIH 6869 04:00:46,400 --> 04:00:47,640 APPLICATIONS THROUGH THE 6870 04:00:47,640 --> 04:00:49,720 EXISTING MUSIC AND HEALTH PUBLIC 6871 04:00:49,720 --> 04:00:50,800 HEALTH ANNOUNCEMENTS AND OTHER 6872 04:00:50,800 --> 04:00:52,120 FUNDING OPPORTUNITIES. 6873 04:00:52,120 --> 04:00:54,240 ALSO THE NETWORKS MAY SUSTAIN 6874 04:00:54,240 --> 04:00:56,320 THE SCIENTIFIC IMPACTS THROUGH 6875 04:00:56,320 --> 04:00:57,640 PUBLICATIONS OF RESEARCH 6876 04:00:57,640 --> 04:00:59,160 FRAMEWORK, COMMON TERMINOLOGIES, 6877 04:00:59,160 --> 04:01:00,480 REVIEWS, AND OTHER BEST 6878 04:01:00,480 --> 04:01:03,000 PRACTICE, AS WELL AS THE OTHER 6879 04:01:03,000 --> 04:01:04,680 DISSEMINATION AND OUTREACH 6880 04:01:04,680 --> 04:01:06,600 STRATEGIES. 6881 04:01:06,600 --> 04:01:08,800 BUT NETWORK ACTIVITIES AND PILOT 6882 04:01:08,800 --> 04:01:12,960 PROJECTS TO BE SUPPORTED, WE 6883 04:01:12,960 --> 04:01:14,600 HOPE, HIGH PRIORITY TOPICS IN 6884 04:01:14,600 --> 04:01:16,360 THREE GENERAL AREAS, INCLUDING 6885 04:01:16,360 --> 04:01:19,200 MUSIC INTERVENTION, MECHANISMS 6886 04:01:19,200 --> 04:01:23,600 AND BIOMARKERS, TECHNOLOGY TOOLS 6887 04:01:23,600 --> 04:01:25,800 AND MODELS. 6888 04:01:25,800 --> 04:01:30,680 FOR MUSIC INTERVENTION, WE WILL 6889 04:01:30,680 --> 04:01:32,040 ENCOURAGE THE RESEARCH NETWORKS 6890 04:01:32,040 --> 04:01:34,960 TO HELP DEFINE DIFFERENTIATE 6891 04:01:34,960 --> 04:01:41,400 DIFFERENT TYPES OF MUSIC-BASED 6892 04:01:41,400 --> 04:01:43,040 INTERVENTIONS, PASSIVE LISTENING 6893 04:01:43,040 --> 04:01:44,720 OR ACTIVE ENGAGEMENT, TO DEFINE 6894 04:01:44,720 --> 04:01:46,880 VARIOUS COMPONENTS OF MUSIC AND 6895 04:01:46,880 --> 04:01:47,960 MUSIC-BASED INTERVENTIONS. 6896 04:01:47,960 --> 04:01:48,960 THAT'S JUST SOME EXAMPLES. 6897 04:01:48,960 --> 04:01:51,960 AND FOR THE MECHANISMS AND 6898 04:01:51,960 --> 04:01:55,200 BIOMARKERS CATEGORY, WE HOPE THE 6899 04:01:55,200 --> 04:01:57,080 RESEARCH NETWORKS WILL HELP TO 6900 04:01:57,080 --> 04:01:59,000 SUPPORT EXPLORATION OF INOH HE 6901 04:01:59,000 --> 04:02:00,680 VAITIVE NEUROMECHANISTIC 6902 04:02:00,680 --> 04:02:03,640 INSIGHTS RELEVANT TO MUSIC AND 6903 04:02:03,640 --> 04:02:05,040 THE SPECIFIC HEALTH CONDITION. 6904 04:02:05,040 --> 04:02:11,040 THAT MAY HELP TO -- AND NOVEL 6905 04:02:11,040 --> 04:02:12,920 MEASURES TO MUSIC-BASED 6906 04:02:12,920 --> 04:02:14,600 INTERVENTION AND THE SPECIFIC 6907 04:02:14,600 --> 04:02:17,120 HEALTH CONDITION OR HELP TO 6908 04:02:17,120 --> 04:02:20,080 DISCOVERY SPONS OF PREDICTIVE 6909 04:02:20,080 --> 04:02:20,960 BIOMARKERS, SIGNATURES, PROFILES 6910 04:02:20,960 --> 04:02:25,120 FOR THIS TYPE OF INTERVENTIONS. 6911 04:02:25,120 --> 04:02:26,640 AND FOR TECHNOLOGY TOOLS AND 6912 04:02:26,640 --> 04:02:29,280 MODELS, WE HOPE THEY WILL HELP 6913 04:02:29,280 --> 04:02:30,400 TO SUPPORT THE DEVELOPMENT OF 6914 04:02:30,400 --> 04:02:34,080 NOVEL TECHNOLOGIES TO MEASURE 6915 04:02:34,080 --> 04:02:35,040 MUSIC-BASED INTERVENTIONS OR 6916 04:02:35,040 --> 04:02:38,600 MONITOR DISEASE-BASED RESPONSES 6917 04:02:38,600 --> 04:02:39,160 TO MUSIC-BASED INTERVENTIONS 6918 04:02:39,160 --> 04:02:41,440 THAT MAY HELP TO DEVELOP OR TEST 6919 04:02:41,440 --> 04:02:42,440 INNOVATIVE ANIMAL MODELS TO 6920 04:02:42,440 --> 04:02:45,160 STUDY MECHANISMS AND BIOMARKERS 6921 04:02:45,160 --> 04:02:47,480 OF THOSE TYPE OF INTERVENTIONS 6922 04:02:47,480 --> 04:02:49,880 OR HELP TO DEVELOP NOVEL 6923 04:02:49,880 --> 04:02:51,080 COMPUTATIONAL MODELS TO STUDY 6924 04:02:51,080 --> 04:02:55,360 THE MECHANISMS OF MUSIC OR MUSIC 6925 04:02:55,360 --> 04:02:56,000 INTERVENTIONS ON SPECIFIC HEALTH 6926 04:02:56,000 --> 04:02:56,480 CONDITIONS. 6927 04:02:56,480 --> 04:03:00,160 SO WE HOPE THAT THE RESEARCH 6928 04:03:00,160 --> 04:03:01,040 NETWORK INITIATIVE WILL BE ABLE 6929 04:03:01,040 --> 04:03:03,000 TO COMPLETE THE FINAL 6930 04:03:03,000 --> 04:03:04,800 RECOMMENDATION FROM THAT 2018 6931 04:03:04,800 --> 04:03:08,400 NEURON PAPER, IN PARTICULAR, TO 6932 04:03:08,400 --> 04:03:09,480 OVERCOME IDENTIFIED RESEARCH 6933 04:03:09,480 --> 04:03:11,240 BARRIERS TO BUILD THE NETWORK 6934 04:03:11,240 --> 04:03:13,080 AND INFRASTRUCTURE TO ADVANCE 6935 04:03:13,080 --> 04:03:14,080 THIS VERY IMPORTANT AREA OF 6936 04:03:14,080 --> 04:03:14,640 SCIENCE. 6937 04:03:14,640 --> 04:03:16,280 I'M GOING TO PAUSE HERE AND 6938 04:03:16,280 --> 04:03:18,440 THANK YOU FOR YOUR ATTENTION AND 6939 04:03:18,440 --> 04:03:21,720 I CERTAINLY HOPE THAT YOU FIND 6940 04:03:21,720 --> 04:03:25,760 THIS CONCEPT COMPELLING AND 6941 04:03:25,760 --> 04:03:26,800 WE'RE LOOKING FOR YOUR COMMENTS 6942 04:03:26,800 --> 04:03:29,040 AND HOPEFULLY YOUR SUPPORT FOR 6943 04:03:29,040 --> 04:03:31,160 THIS CONCEPT PROPOSAL. 6944 04:03:31,160 --> 04:03:32,680 THANK YOU, I'M GOING TO PAUSE 6945 04:03:32,680 --> 04:03:34,120 RIGHT HERE AND MOVE ON TO THE 6946 04:03:34,120 --> 04:03:39,240 NEXT SLIDE ABOUT QUESTIONS. 6947 04:03:39,240 --> 04:03:41,880 >> THANK YOU, DR. CHEN. 6948 04:03:41,880 --> 04:03:44,640 COMMENTS OR QUESTIONS FROM 6949 04:03:44,640 --> 04:03:54,800 COUNCIL? 6950 04:04:04,480 --> 04:04:08,000 THERE WE GO. 6951 04:04:08,000 --> 04:04:16,640 DR. LEF RETS LEF LAVRETS. 6952 04:04:16,640 --> 04:04:20,520 >> THIS 6953 04:04:20,520 --> 04:04:24,560 >> THAT'S A VERY GOOD QUESTION, 6954 04:04:24,560 --> 04:04:24,880 DR. LAVRETSKY. 6955 04:04:24,880 --> 04:04:27,320 THIS IS SORT OF A RESEARCH 6956 04:04:27,320 --> 04:04:32,440 NETWORK BUILDING THAT WILL BRING 6957 04:04:32,440 --> 04:04:33,680 DIFFERENT -- INVESTIGATORS FROM 6958 04:04:33,680 --> 04:04:36,680 DIFFERENT DISCIPLINES TOGETHER, 6959 04:04:36,680 --> 04:04:40,040 AND BUILD -- THREE PROJECTS SO 6960 04:04:40,040 --> 04:04:41,360 THEY CAN GENERATE THE 6961 04:04:41,360 --> 04:04:42,560 PRELIMINARY DATA THAT WILL HELP 6962 04:04:42,560 --> 04:04:45,800 THEM TO BE COMPETITIVE FOR 6963 04:04:45,800 --> 04:04:51,120 R21s, R01s OR EVEN R -- 33. 6964 04:04:51,120 --> 04:04:54,360 SO WE HAVE THE PREVIOUS 6965 04:04:54,360 --> 04:04:57,480 INITIATIVE EFFORTS, WE STILL 6966 04:04:57,480 --> 04:04:59,080 REALIZE THAT THAT'S A VERY 6967 04:04:59,080 --> 04:05:00,600 CHALLENGING GAP THAT HAS NOT YET 6968 04:05:00,600 --> 04:05:03,320 TO BE OVERCOME AND THIS SL SORT 6969 04:05:03,320 --> 04:05:05,800 OF THE FINAL PIECE OF THE PUZZLE 6970 04:05:05,800 --> 04:05:08,880 WE'RE HOPING TO ADVANCE THE 6971 04:05:08,880 --> 04:05:09,680 FIELD, SO REALLY SEEDING THOSE 6972 04:05:09,680 --> 04:05:10,400 PILOT PROJECTS. 6973 04:05:10,400 --> 04:05:12,160 IT'S NOT QUITE -- WE DON'T 6974 04:05:12,160 --> 04:05:13,560 REALLY -- NIH OTHERWISE DON'T 6975 04:05:13,560 --> 04:05:15,800 REALLY QUITE HAVE FUNDING 6976 04:05:15,800 --> 04:05:18,400 MECHANISMS EXCEPT TO R03, WHICH 6977 04:05:18,400 --> 04:05:20,680 IS ALSO A SOMEWHAT PROBLEMATIC 6978 04:05:20,680 --> 04:05:23,040 ON ITS OWN. 6979 04:05:23,040 --> 04:05:26,280 SO WE FELT THIS WAY, WE CAN 6980 04:05:26,280 --> 04:05:27,680 REALLY -- THIS KIND OF RESEARCH 6981 04:05:27,680 --> 04:05:29,880 NETWORKS, WE CAN HELP TO BUILD 6982 04:05:29,880 --> 04:05:32,640 THAT KIND OF COLLABORATION 6983 04:05:32,640 --> 04:05:35,360 RESEARCH NETWORKS FOR THE 6984 04:05:35,360 --> 04:05:35,720 INVESTIGATORS. 6985 04:05:35,720 --> 04:05:39,680 >> SO WOULDN'T IT BE CRITERIA 6986 04:05:39,680 --> 04:05:41,040 FOR INVESTIGATORS JOINING THIS 6987 04:05:41,040 --> 04:05:41,280 NETWORK? 6988 04:05:41,280 --> 04:05:43,880 IF THEY'RE NOT PROPOSING 6989 04:05:43,880 --> 04:05:44,760 RESEARCH PROJECTS INITIALLY, HOW 6990 04:05:44,760 --> 04:05:51,480 WOULD YOU SELECT THEM? 6991 04:05:51,480 --> 04:05:53,200 >> I HAVE TO BE CAREFUL OF WHAT 6992 04:05:53,200 --> 04:05:57,480 I'M SAYING HERE. 6993 04:05:57,480 --> 04:05:58,560 SO LET ME THINK ABOUT HOW TO 6994 04:05:58,560 --> 04:06:01,840 ANSWER THAT QUESTION. 6995 04:06:01,840 --> 04:06:03,080 THE PILOT PROJECT COMPONENTS IN 6996 04:06:03,080 --> 04:06:05,160 THE RESEARCH NETWORKS WHERE I 6997 04:06:05,160 --> 04:06:10,520 THINK IF THEY CAN DEFINE IN MY 6998 04:06:10,520 --> 04:06:13,520 LAST SLIDE, THE PRIORITY TOPICS, 6999 04:06:13,520 --> 04:06:16,080 FOR EXAMPLE, AND THEN REALLY 7000 04:06:16,080 --> 04:06:18,920 TYPICAL WOULD DO PRETTY BROAD 7001 04:06:18,920 --> 04:06:22,520 CALL TO -- BEYOND THE ACTUAL 7002 04:06:22,520 --> 04:06:25,920 INSTITUTIONS THAT'S RECEIVING 7003 04:06:25,920 --> 04:06:26,800 SUPPORT, SO REALLY PUBLIC CALL 7004 04:06:26,800 --> 04:06:30,320 FOR COMPETITION TO SUBMIT IDEAS. 7005 04:06:30,320 --> 04:06:32,520 SO THOSE IDEAS CAN BE FUNDED 7006 04:06:32,520 --> 04:06:34,720 THROUGH THE RESEARCH NETWORK TO 7007 04:06:34,720 --> 04:06:37,120 DO THOSE PILOT PROJECTS. 7008 04:06:37,120 --> 04:06:38,680 DOES THAT ANSWER YOUR QUESTION, 7009 04:06:38,680 --> 04:06:38,880 I HOPE? 7010 04:06:38,880 --> 04:06:40,400 >> MORE OR LESS, YES. 7011 04:06:40,400 --> 04:06:43,400 THANK YOU. 7012 04:06:43,400 --> 04:06:48,680 >> WEN, LET ME JUST ADD, WHEN WE 7013 04:06:48,680 --> 04:06:51,840 PULL OUT THOSE CALLS FOR -- YOU 7014 04:06:51,840 --> 04:06:52,720 KNOW, THOSE MULTIDISCIPLINARY 7015 04:06:52,720 --> 04:06:54,400 NETWORK, WE ALWAYS HAVE THE SET 7016 04:06:54,400 --> 04:06:56,640 OF HIGH PRIORITY TOPIC, AND 7017 04:06:56,640 --> 04:06:58,320 REALLY THE INVESTIGATORS THAT 7018 04:06:58,320 --> 04:07:00,920 ACTUALLY ARE SUCCESSFUL ARE 7019 04:07:00,920 --> 04:07:03,800 GROUPS THAT CAN FULLY 7020 04:07:03,800 --> 04:07:05,000 DEMONSTRATE THE EXPERTISE THAT 7021 04:07:05,000 --> 04:07:06,080 THEY'RE BRINGING TOGETHER WOULD 7022 04:07:06,080 --> 04:07:09,480 BE ABLE TO ADDRESS ONE TO THREE 7023 04:07:09,480 --> 04:07:12,640 OF THOSE HIGH PRIORITY TOPICS. 7024 04:07:12,640 --> 04:07:14,160 SO IT'S NOT ONLY THROUGH THE 7025 04:07:14,160 --> 04:07:16,920 PILOT PROJECT, IT'S REALLY 7026 04:07:16,920 --> 04:07:18,760 THROUGH BRINGING THOSE 7027 04:07:18,760 --> 04:07:19,880 PARTICIPANTS TOGETHER TO BE ABLE 7028 04:07:19,880 --> 04:07:24,360 TO CONCEPTUALIZE MORE SCIENTIFIC 7029 04:07:24,360 --> 04:07:25,760 PROJECT THAT WOULD MOVE THE 7030 04:07:25,760 --> 04:07:26,280 FIELD FORWARD. 7031 04:07:26,280 --> 04:07:27,400 AND THAT'S ONE OF THE CRITERIA 7032 04:07:27,400 --> 04:07:33,040 THAT WE HAVE TO EVALUATE, 7033 04:07:33,040 --> 04:07:35,000 SUCCESSFUL APPLICATIONS AND 7034 04:07:35,000 --> 04:07:36,680 SUCH, THE PROPOSAL. 7035 04:07:36,680 --> 04:07:37,560 >> DR. MEHLING? 7036 04:07:37,560 --> 04:07:39,960 >> JUST A BRIEF CURIOSITY 7037 04:07:39,960 --> 04:07:41,480 QUESTION. 7038 04:07:41,480 --> 04:07:45,240 LIKE MUSIC FOR PARKINSONISM, A 7039 04:07:45,240 --> 04:07:46,280 MOVEMENT DISEASE, SO MY QUESTION 7040 04:07:46,280 --> 04:07:47,520 WOULD BE, IS DANCE INCLUDED OR 7041 04:07:47,520 --> 04:07:52,000 IS IT EXCLUDED FROM THIS KIND OF 7042 04:07:52,000 --> 04:07:52,200 TOPIC? 7043 04:07:52,200 --> 04:07:54,320 >> IT DEPENDS. 7044 04:07:54,320 --> 04:07:59,120 IF DANCE -- WE DO DANCE TO MUSIC 7045 04:07:59,120 --> 04:08:02,800 SO YES, IT WOULD BE CONSIDERED A 7046 04:08:02,800 --> 04:08:03,600 MUSIC-BASED INTERVENTION. 7047 04:08:03,600 --> 04:08:05,600 UNLESS THERE'S NO -- I DON'T 7048 04:08:05,600 --> 04:08:06,760 KNOW -- THAT WOULDN'T BE CALLED 7049 04:08:06,760 --> 04:08:09,080 DANCE, I GUESS. 7050 04:08:09,080 --> 04:08:12,920 >> YOU COULD USE A MET TROA 7051 04:08:12,920 --> 04:08:13,120 NOME. 7052 04:08:13,120 --> 04:08:15,480 >> ACTUALLY THAT'S STILL RHYTHM. 7053 04:08:15,480 --> 04:08:15,960 >> TRUE. 7054 04:08:15,960 --> 04:08:18,400 THAT'S TRUE. 7055 04:08:18,400 --> 04:08:24,440 >> IS DRUMMING MUSIC? 7056 04:08:24,440 --> 04:08:24,880 >> YEAH. 7057 04:08:24,880 --> 04:08:25,680 >> YES? 7058 04:08:25,680 --> 04:08:27,920 >> RHYTHM IS A COMPONENT OF 7059 04:08:27,920 --> 04:08:33,160 MUSIC, AND THAT'S HOW WE HAVE 7060 04:08:33,160 --> 04:08:34,280 ACTUALLY -- THUS FAR WE WOULD 7061 04:08:34,280 --> 04:08:36,920 INCLUDE THOSE AS PART OF 7062 04:08:36,920 --> 04:08:43,040 MUSIC-BASED INTERVENTIONS. 7063 04:08:43,040 --> 04:08:44,640 >> OKAY. 7064 04:08:44,640 --> 04:08:46,280 UNLESS THERE ARE ANY OTHER 7065 04:08:46,280 --> 04:08:47,400 CRITICAL QUESTIONS TO POSE, THEN 7066 04:08:47,400 --> 04:08:49,040 LET'S GO AHEAD AND VOTE ON THIS 7067 04:08:49,040 --> 04:08:51,680 CONCEPT CLEARANCE. 7068 04:08:51,680 --> 04:08:52,440 ON YOUR SCREEN YOU'LL SEE A 7069 04:08:52,440 --> 04:08:52,880 POLL. 7070 04:08:52,880 --> 04:08:54,320 VOTING FOR YES MEANS YOU'RE 7071 04:08:54,320 --> 04:08:55,720 VOTING IN FAVOR OF THE CONCEPT, 7072 04:08:55,720 --> 04:08:57,880 NO MEANS YOU'RE IN OPPOSITION, 7073 04:08:57,880 --> 04:09:08,200 AND YOU MAY ABSTAIN. 7074 04:09:17,080 --> 04:09:18,240 SO IT IS UNANIMOUS VOTE IN FAVOR 7075 04:09:18,240 --> 04:09:21,080 OF THIS CONCEPT. 7076 04:09:21,080 --> 04:09:22,200 SO IT CARRIES. 7077 04:09:22,200 --> 04:09:23,720 THANKS VERY MUCH. 7078 04:09:23,720 --> 04:09:24,120 THANKS, DR. CHEN. 7079 04:09:24,120 --> 04:09:24,920 >> THANK YOU. 7080 04:09:24,920 --> 04:09:27,480 >> SO THE LAST THING ON THE 7081 04:09:27,480 --> 04:09:29,960 AGENDA IS JUST A REMINDER FOR 7082 04:09:29,960 --> 04:09:35,360 THE PUBLIC, IF YOU WISH TO MAKE 7083 04:09:35,360 --> 04:09:37,120 A PUBLIC COMMENT AGAIN, BECAUSE 7084 04:09:37,120 --> 04:09:38,840 WE'RE DOING THIS VIRTUALLY, 7085 04:09:38,840 --> 04:09:40,600 PLEASE YOU MAY SUBMIT THOSE 7086 04:09:40,600 --> 04:09:43,200 COMMENTS IN WRITING, EITHER BY 7087 04:09:43,200 --> 04:09:46,080 EMAIL OR A HARD COPY WHICH COULD 7088 04:09:46,080 --> 04:09:46,760 BE MAILED. 7089 04:09:46,760 --> 04:09:48,600 AGAIN, IT NEEDS TO BE RECEIVED 7090 04:09:48,600 --> 04:09:50,880 WITHIN 15 DAYS OF THIS MEETING. 7091 04:09:50,880 --> 04:09:54,680 AND THEN THESE WILL BE SHARED 7092 04:09:54,680 --> 04:09:56,360 WITH COUNCIL BY OUR ELECTRONIC 7093 04:09:56,360 --> 04:10:01,200 COUNCIL BOOK. 7094 04:10:01,200 --> 04:10:06,840 DR. LA VETS KEY, LAVRETS? 7095 04:10:06,840 --> 04:10:08,840 >> I WAS TRYING TO SUBMIT RFI 7096 04:10:08,840 --> 04:10:10,760 FOR WHOLE HEALTH AND THE WEBSITE 7097 04:10:10,760 --> 04:10:12,360 REJECTED MY SUBMISSION. 7098 04:10:12,360 --> 04:10:13,640 CAN YOU PLEASE CHECK THAT IT'S 7099 04:10:13,640 --> 04:10:13,880 WORKING? 7100 04:10:13,880 --> 04:10:15,200 >> WE WILL CHECK THAT. 7101 04:10:15,200 --> 04:10:16,200 THANK YOU VERY MUCH FOR LETTING 7102 04:10:16,200 --> 04:10:17,400 US KNOW. 7103 04:10:17,400 --> 04:10:20,640 YOU'RE IN THE . 7104 04:10:20,640 --> 04:10:22,040 IN THE ROOM IS DIRECTOR OF THAT 7105 04:10:22,040 --> 04:10:24,440 WEBSITE SO IT WILL BE TAKEN CARE 7106 04:10:24,440 --> 04:10:25,200 OF VERY PROMPTLY. 7107 04:10:25,200 --> 04:10:25,960 THANK YOU VERY MUCH. 7108 04:10:25,960 --> 04:10:28,360 LET ME JUST ASK IF THERE ARE ANY 7109 04:10:28,360 --> 04:10:36,560 FINAL COMMENTS BY DRS. EDWARD, 7110 04:10:36,560 --> 04:10:39,160 SHIRTLIVE OR DR. LANGEVIN? 7111 04:10:39,160 --> 04:10:40,720 EMMELINE, ANY FINAL COMMENTS FOR 7112 04:10:40,720 --> 04:10:40,960 COUNCIL? 7113 04:10:40,960 --> 04:10:42,080 >> I WANT TO THANK EVERYBODY FOR 7114 04:10:42,080 --> 04:10:44,560 A VERY, VERY EXCITING DAY, AND 7115 04:10:44,560 --> 04:10:46,120 WE HEARD SOME REALLY GREAT 7116 04:10:46,120 --> 04:10:49,480 DISCUSSION AND WE'RE VERY 7117 04:10:49,480 --> 04:10:50,920 GRATEFUL THAT THE HYBRID MEETING 7118 04:10:50,920 --> 04:10:52,320 ACTUALLY WORKED PRETTY WELL. 7119 04:10:52,320 --> 04:10:53,200 SO THAT WAS GOOD. 7120 04:10:53,200 --> 04:10:54,320 THANK YOU. 7121 04:10:54,320 --> 04:10:57,160 >> THANK YOU, DR. EDWARDS. 7122 04:10:57,160 --> 04:10:58,880 >> AND I'LL JUST ADD, THANK YOU 7123 04:10:58,880 --> 04:11:00,320 TO COUNCIL FOR ALL YOUR 7124 04:11:00,320 --> 04:11:04,600 ENTHUSIASM AND CONSTRUCTIVE 7125 04:11:04,600 --> 04:11:05,480 FEEDBACK. 7126 04:11:05,480 --> 04:11:07,640 REALLY I THINK FOR US, 7127 04:11:07,640 --> 04:11:08,640 VALIDATING WHAT WE'RE DOING AS A 7128 04:11:08,640 --> 04:11:10,520 CENTER IS REALLY GRATIFYING, SO 7129 04:11:10,520 --> 04:11:12,560 WITH MUCH GRATITUDE WITH YOU, 7130 04:11:12,560 --> 04:11:13,320 COUNCILMEMBERS, FOR YOUR ADVICE. 7131 04:11:13,320 --> 04:11:15,200 I JUST WANT TO PUT A SHOUT OUT 7132 04:11:15,200 --> 04:11:17,040 TO ALL OUR STAFF WHO REALLY MAKE 7133 04:11:17,040 --> 04:11:17,840 ALL THIS HAPPEN. 7134 04:11:17,840 --> 04:11:20,920 IT'S VERY EXCITING TO BE PART OF 7135 04:11:20,920 --> 04:11:22,200 THIS GROUP AND WORKING WITH BOTH 7136 04:11:22,200 --> 04:11:23,840 COUNCIL AND WITH OUR STAFF AND 7137 04:11:23,840 --> 04:11:25,000 WITH THE EXTRAMURAL COMMUNITY, 7138 04:11:25,000 --> 04:11:25,920 SO THANK YOU SO MUCH. 7139 04:11:25,920 --> 04:11:28,640 >> THANK YOU. 7140 04:11:28,640 --> 04:11:29,000 DR. LANGEVIN. 7141 04:11:29,000 --> 04:11:32,840 >> SO I REALLY LIKED THE COMMENT 7142 04:11:32,840 --> 04:11:34,720 THAT LORI JUST PUT IN THE CHAT 7143 04:11:34,720 --> 04:11:36,040 ABOUT WITNESSING THE WHOLE 7144 04:11:36,040 --> 04:11:37,760 THREAD OF WHOLE PERSON RESEARCH 7145 04:11:37,760 --> 04:11:38,200 THROUGHOUT THE DAY. 7146 04:11:38,200 --> 04:11:41,200 YOU KNOW, THE THING THAT AMAZES 7147 04:11:41,200 --> 04:11:42,720 ME AT EVERY ONE OF THESE COUNCIL 7148 04:11:42,720 --> 04:11:47,760 SESSIONS IS REALLY A 7149 04:11:47,760 --> 04:11:49,640 CROSS-SECTIONAL SNAPSHOT AT ONE 7150 04:11:49,640 --> 04:11:50,040 POINT IN TIME. 7151 04:11:50,040 --> 04:11:52,360 WHAT YOU'RE SEEING IS THIS 7152 04:11:52,360 --> 04:11:55,560 ENTIRE ARC WHICH IABLE ONLY NOW 7153 04:11:55,560 --> 04:11:57,400 BEGINNING TO EXPERIENCE AFTER 7154 04:11:57,400 --> 04:12:00,200 DURING MY TIME AS NCCIH 7155 04:12:00,200 --> 04:12:00,880 DIRECTOR. 7156 04:12:00,880 --> 04:12:02,880 BETWEEN FORMULATING A CONCEPT -- 7157 04:12:02,880 --> 04:12:07,920 IDENTIFYING THE GAP FIRST OF 7158 04:12:07,920 --> 04:12:08,680 ALL,, THEN FORMULATING THE 7159 04:12:08,680 --> 04:12:10,120 CONCEPT AS YOU SAW SOME OF 7160 04:12:10,120 --> 04:12:11,560 TODAY, AND ISSUING THE FUNDING 7161 04:12:11,560 --> 04:12:12,440 OPPORTUNITY, WHICH -- THAT'S A 7162 04:12:12,440 --> 04:12:15,080 LOT OF WORK TOO, THEN RECEIVING 7163 04:12:15,080 --> 04:12:18,680 AND REVIEWING THE APPLICATION, 7164 04:12:18,680 --> 04:12:20,040 AND THEN EVENTUALLY ISSUING THE 7165 04:12:20,040 --> 04:12:20,320 AWARDS. 7166 04:12:20,320 --> 04:12:24,160 THIS IS A CYCLE THAT LASTS WAY 7167 04:12:24,160 --> 04:12:25,040 MORE THAN A YEAR ACTUALLY. 7168 04:12:25,040 --> 04:12:26,560 AND SO IT TAKES A LONG TIME 7169 04:12:26,560 --> 04:12:31,040 BEFORE YOU CAN THIS CYCLE MANY 7170 04:12:31,040 --> 04:12:31,600 TIMES. 7171 04:12:31,600 --> 04:12:35,960 THAT'S WHY WE TRY TO EMBRICATE 7172 04:12:35,960 --> 04:12:36,600 LOTS OF DIFFERENT THINGS THAT 7173 04:12:36,600 --> 04:12:37,760 ARE GOING TO FEED ON EACH OTHER 7174 04:12:37,760 --> 04:12:40,680 SO YOU DON'T HAVE TO WAIT UNTIL 7175 04:12:40,680 --> 04:12:42,280 ONE CYCLE IS COMPLETELY OVER 7176 04:12:42,280 --> 04:12:43,240 BEFORE YOU START THE NEXT ONE. 7177 04:12:43,240 --> 04:12:45,000 SO THIS IS REALLY COMPLICATED 7178 04:12:45,000 --> 04:12:49,240 AND IT REQUIRES -- I CANNOT SAY 7179 04:12:49,240 --> 04:12:50,720 ENOUGH ABOUT A FABULOUS TEAM WE 7180 04:12:50,720 --> 04:12:53,720 HAVE, SO, SO IMPRESSIVE. 7181 04:12:53,720 --> 04:12:56,000 WHAT YOU WITNESS AS 7182 04:12:56,000 --> 04:12:56,920 COUNCILMEMBERS, MOSTLY PEOPLE 7183 04:12:56,920 --> 04:13:01,040 WHO TALK HERE ARE MOSTLY 7184 04:13:01,040 --> 04:13:02,920 REPRESENTING A PROGRAM, BUT 7185 04:13:02,920 --> 04:13:05,640 THERE'S ALSO BEHIND ALL OF THAT 7186 04:13:05,640 --> 04:13:06,600 OBVIOUSLY REVIEW, THERE'S ALL 7187 04:13:06,600 --> 04:13:07,960 EXTRAMURAL ACTIVITY, THERE'S 7188 04:13:07,960 --> 04:13:10,920 GRANTS MANAGEMENT, THERE'S 7189 04:13:10,920 --> 04:13:12,080 OFFICE OF ADMINISTRATIVE 7190 04:13:12,080 --> 04:13:13,320 OPERATIONS, THERE'S 7191 04:13:13,320 --> 04:13:15,160 COMMUNICATION, I.T., POLICY, 7192 04:13:15,160 --> 04:13:15,600 PLANNING EVALUATION. 7193 04:13:15,600 --> 04:13:18,280 ALL OF THESE PEOPLE ARE REALLY 7194 04:13:18,280 --> 04:13:20,000 KIND OF WORKING TOGETHER TO MAKE 7195 04:13:20,000 --> 04:13:22,600 THIS A SMOOTH RUNNING MACHINE. 7196 04:13:22,600 --> 04:13:26,800 I CAN'T TELL YOU, YOU KNOW, HOW 7197 04:13:26,800 --> 04:13:29,120 GRATEFUL I AM FOR ALL OF THE 7198 04:13:29,120 --> 04:13:31,720 HARD WORK THAT EVERYBODY AT 7199 04:13:31,720 --> 04:13:35,040 NCCIH PUTS TO MAKE ALL OF THIS 7200 04:13:35,040 --> 04:13:35,440 HAPPEN. 7201 04:13:35,440 --> 04:13:37,760 AND ESPECIALLY TO OUR IT TEAM 7202 04:13:37,760 --> 04:13:39,960 TODAY THAT REALLY WENT THROUGH 7203 04:13:39,960 --> 04:13:42,000 MANY DIFFERENT REHEARSALS TO 7204 04:13:42,000 --> 04:13:44,440 MAKE SURE THAT -- AND DID PUT A 7205 04:13:44,440 --> 04:13:46,200 LOT OF THOUGHT AND EFFORT INTO 7206 04:13:46,200 --> 04:13:47,240 MAKING THIS HYBRID MEETING. 7207 04:13:47,240 --> 04:13:48,680 AS FAR AS I CAN TELL, WE WOULD 7208 04:13:48,680 --> 04:13:50,480 LOVE TO HEAR YOUR FEEDBACK FROM 7209 04:13:50,480 --> 04:13:51,680 WHAT IT WAS LIKE FROM THE ZOOM 7210 04:13:51,680 --> 04:13:53,040 END OF THINGS. 7211 04:13:53,040 --> 04:13:57,320 I CAN SAY THAT FROM THE ROOM 7212 04:13:57,320 --> 04:14:00,680 SIDE, I REALLY FELT DIFFERENT, 7213 04:14:00,680 --> 04:14:02,360 AND ACTUALLY REALLY NICE 7214 04:14:02,360 --> 04:14:05,120 COMPARED TO BEING ON -- FOR ME 7215 04:14:05,120 --> 04:14:07,320 PERSONALLY, I REALLY -- SO I'M 7216 04:14:07,320 --> 04:14:13,120 REALLY HOPING THAT IF WE DO HAVE 7217 04:14:13,120 --> 04:14:15,120 AN OPPORTUNITY TO GET TOGETHER 7218 04:14:15,120 --> 04:14:16,400 IN THE FALL, THAT MANY OF YOU 7219 04:14:16,400 --> 04:14:18,920 WILL TAKE THE OPPORTUNITY TO DO 7220 04:14:18,920 --> 04:14:19,800 SO. 7221 04:14:19,800 --> 04:14:21,680 I REALLY, REALLY WOULD LOVE TO 7222 04:14:21,680 --> 04:14:24,400 MEET IN PERSON THOSE 7223 04:14:24,400 --> 04:14:29,520 COUNCILMEMBERS WHO HAVE JOINED 7224 04:14:29,520 --> 04:14:32,240 US WHILE WE WERE VIRTUAL, AND OF 7225 04:14:32,240 --> 04:14:34,920 COURSE ALL OUR OLD FRIENDS WE 7226 04:14:34,920 --> 04:14:35,680 HAD FROM BEFORE. 7227 04:14:35,680 --> 04:14:38,040 I LOVED BEN'S COMMENTS, ONE OF 7228 04:14:38,040 --> 04:14:39,280 THE BEST RUN HYBRID MEETINGS. 7229 04:14:39,280 --> 04:14:41,920 I HAVE TO SAY, I AGREE. 7230 04:14:41,920 --> 04:14:44,080 I'VE ATTENDED SOME NOT SO GOOD 7231 04:14:44,080 --> 04:14:45,400 HYBRID MEETINGS RECENTLY, AND I 7232 04:14:45,400 --> 04:14:46,720 THINK THIS ONE ACTUALLY WENT 7233 04:14:46,720 --> 04:14:49,040 PRETTY WELL. 7234 04:14:49,040 --> 04:14:51,320 SO GRATEFUL TO ALL OF YOU, AND 7235 04:14:51,320 --> 04:14:52,960 YOU'LL BE HEARING, OF COURSE, 7236 04:14:52,960 --> 04:14:55,680 UPDATES FROM US AS TO WHAT WE'RE 7237 04:14:55,680 --> 04:14:56,680 GOING TO DO WITH FUTURE 7238 04:14:56,680 --> 04:14:57,240 MEETINGS. 7239 04:14:57,240 --> 04:15:00,280 BUT WE WOULD LOVE YOUR INPUT 7240 04:15:00,280 --> 04:15:01,600 ABOUT HOW YOU FEEL ABOUT THIS, 7241 04:15:01,600 --> 04:15:03,360 WHETHER YOU WOULD BE EXCITED IN 7242 04:15:03,360 --> 04:15:05,440 COMING BACK IN PERSON AND WE'LL 7243 04:15:05,440 --> 04:15:07,720 TRY TO MAKE IT FUN. 7244 04:15:07,720 --> 04:15:09,720 SO GREAT. 7245 04:15:09,720 --> 04:15:11,040 ANYWAY, THANK YOU VERY MUCH, 7246 04:15:11,040 --> 04:15:12,440 EVERYONE. 7247 04:15:12,440 --> 04:15:14,640 AND I GUESS THAT'S IT. 7248 04:15:14,640 --> 04:15:16,400 >> SO I'D ALSO JUST LIKE TO 7249 04:15:16,400 --> 04:15:17,920 EXTEND MY PERSONAL THANKS TO ALL 7250 04:15:17,920 --> 04:15:20,680 OUR STAFF WHO HAVE MADE THIS 7251 04:15:20,680 --> 04:15:21,960 MEETING HAPPEN. 7252 04:15:21,960 --> 04:15:24,480 IT'S AN HONOR TO WORK WITH THEM. 7253 04:15:24,480 --> 04:15:26,360 AND WE WILL -- IN TERMS OF THE 7254 04:15:26,360 --> 04:15:27,560 SEPTEMBER MEETING, AGAIN, THE 7255 04:15:27,560 --> 04:15:29,440 AUGUST MEETING AT COUNCIL, THE 7256 04:15:29,440 --> 04:15:30,720 CLOSED SESSION ONLY MEETING, 7257 04:15:30,720 --> 04:15:33,360 THAT WILL BE HELD VIRTUALLY. 7258 04:15:33,360 --> 04:15:36,880 IT'S THE SEPTEMBER MEETING WHICH 7259 04:15:36,880 --> 04:15:39,360 WE'RE CONSIDERING HOLDING AS A 7260 04:15:39,360 --> 04:15:40,560 HYBRID MEETING IN WHICH 7261 04:15:40,560 --> 04:15:42,760 COUNCILMEMBERS COULD ALSO COME 7262 04:15:42,760 --> 04:15:43,200 OPTIONALLY. 7263 04:15:43,200 --> 04:15:44,960 IT WAS NOT A REQUIREMENT THAT 7264 04:15:44,960 --> 04:15:47,160 COUNCIL WOULD HAVE TO HAVE COME 7265 04:15:47,160 --> 04:15:51,400 IN PERSON TO THE CONTRARY, BUT 7266 04:15:51,400 --> 04:15:52,480 IT WOULD BE AB OPTION. 7267 04:15:52,480 --> 04:15:53,800 NOW THIS OF COURSE IS GOING TO 7268 04:15:53,800 --> 04:15:55,560 BE CONTINGENT UPON WHETHER IT'S 7269 04:15:55,560 --> 04:15:58,720 SAFE TO TRAVEL AND ALL THOSE 7270 04:15:58,720 --> 04:16:00,160 THINGS AND ALL THE THINGS WE 7271 04:16:00,160 --> 04:16:02,320 KNOW TOO WELL AT THIS POINT 7272 04:16:02,320 --> 04:16:03,480 AFTER TWO YEARS PLUS OF LIVING 7273 04:16:03,480 --> 04:16:06,960 WITH COVID. 7274 04:16:06,960 --> 04:16:08,360 BUT WE WILL COMMUNICATE WITH YOU 7275 04:16:08,360 --> 04:16:14,120 THIS SUMMER ABOUT OUR BEST 'FESS 7276 04:16:14,120 --> 04:16:15,520 AS TO WHETHER WE WILL BE ABLE TO 7277 04:16:15,520 --> 04:16:17,360 HOLD THIS TO IN-PERSON OPTION 7278 04:16:17,360 --> 04:16:19,360 FOR COUNCILMEMBERS AND IF SO, 7279 04:16:19,360 --> 04:16:20,320 WE'LL ACTIVATE THE USUAL 7280 04:16:20,320 --> 04:16:22,200 MACHINERY THAT THOSE OF YOU WHO 7281 04:16:22,200 --> 04:16:24,200 HAVE BEEN AROUND FOR A FEW YEARS 7282 04:16:24,200 --> 04:16:27,120 ANYWAY KNOW ABOUT HOW WE MAKE 7283 04:16:27,120 --> 04:16:29,080 PLANE RESERVATIONS AND HOTEL 7284 04:16:29,080 --> 04:16:31,040 RESERVATIONS AND GET YOU FED AND 7285 04:16:31,040 --> 04:16:33,120 FROM THE HOTEL TO HERE AND ALL 7286 04:16:33,120 --> 04:16:34,360 THOSE KINDS OF THINGS. 7287 04:16:34,360 --> 04:16:37,400 SO STAY TUNED, AND WE'RE VERY 7288 04:16:37,400 --> 04:16:39,520 EXCITED ABOUT THE POSSIBILITY AS 7289 04:16:39,520 --> 04:16:40,160 WELL. 7290 04:16:40,160 --> 04:16:42,280 AND WITH THAT, THEN I'LL GO 7291 04:16:42,280 --> 04:16:44,680 AHEAD, WE'LL CONCLUDE THIS 7292 04:16:44,680 --> 04:16:45,960 MEETING, THE 80TH MEETING OF THE 7293 04:16:45,960 --> 04:16:47,600 NATIONAL ADVISORY COUNCIL FOR 7294 04:16:47,600 --> 04:16:48,680 COMPLEMENTARY AND INTEGRATIVE 7295 04:16:48,680 --> 04:16:48,920 HEALTH. 7296 04:16:48,920 --> 04:16:49,360 THANK YOU VERY MUCH. 7297 04:16:49,360 --> 04:16:51,160 IT'S BEEN GREAT BEING WITH YOU 7298 04:16:51,160 --> 04:16:53,160 ALL DAY, AND I HOPE YOU ALL HAVE 7299 04:16:53,160 --> 00:00:00,000 A GREAT WEEKEND AS WELL.