1
00:00:08,320 --> 00:00:12,760
>>THESE REGARDING ANY
ITEMS

2
00:00:12,760 --> 00:00:14,440
DISCUSSED DURING THIS MEETING

3
00:00:14,440 --> 00:00:17,040
AND DO SO BY WRITING -- PLEASE

4
00:00:17,040 --> 00:00:18,720
MAKE SURE EVERYBODY IS MUTED.

5
00:00:18,720 --> 00:00:23,320
WRITING TO Dr. PAULETTE GRAY

6
00:00:23,320 --> 00:00:24,440
EXECUTIVE SECRETARY OF THE NCAB

7
00:00:24,440 --> 00:00:26,000
WITHIN 10 DAYS OF THE MEETING.

8
00:00:26,000 --> 00:00:27,480
ANY WRITTEN STATEMENTS OR

9
00:00:27,480 --> 00:00:29,640
QUESTIONS WILL RECEIVE CAREFUL

10
00:00:29,640 --> 00:00:31,680
CONSIDERATION.

11
00:00:31,680 --> 00:00:34,600
THE FOLLOWING NCAB SUBCOMMITTEE

12
00:00:34,600 --> 00:00:39,720
MEMBERS ARE PARTICIP PARTICIPATE

13
00:00:39,720 --> 00:00:40,040
MEETING.

14
00:00:40,040 --> 00:00:44,480
[ROLL CALL]

15
00:00:44,480 --> 00:00:45,880
>>THERE'S A QUORUM.

16
00:00:45,880 --> 00:00:49,440
ARE THERE ANY QUESTIONS

17
00:00:49,440 --> 00:00:52,520
REGARDING PROCESS?

18
00:00:52,520 --> 00:00:53,880
>>THANK YOU SO MUCH,
EVERYBODY

19
00:00:53,880 --> 00:00:59,240
FOR JOINING US TODAY.

20
00:00:59,240 --> 00:01:00,080
IT'S GOOD TO SEE EVERYBODY.

21
00:01:00,080 --> 00:01:03,120
I HOPE EVERYONE IS DOING WELL.

22
00:01:03,120 --> 00:01:05,640
SO, WE HAVE KIND OF A VERY OPEN

23
00:01:05,640 --> 00:01:07,800
AGENDA TODAY.

24
00:01:07,800 --> 00:01:12,600
I WOULD LIKE TO IF OVER THE

25
00:01:12,600 --> 00:01:14,840
CHARGE OF THIS AD HOC

26
00:01:14,840 --> 00:01:18,120
SUBCOMMITTEE AND THEN HAVE AN

27
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OPEN DISCUSSION WHERE WE'RE

28
00:01:18,960 --> 00:01:23,880
GOING TO GO NEXT AND SO PHIL, DO

29
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YOU HAVE ANYTHING TO SAY BEFORE

30
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WE START.

31
00:01:30,960 --> 00:01:31,320
IT'S ALL YOURS.

32
00:01:31,320 --> 00:01:31,720
>>OK.

33
00:01:31,720 --> 00:01:36,680
ALL RIGHT.

34
00:01:36,680 --> 00:01:39,680
THANK YOU.

35
00:01:39,680 --> 00:01:41,360
>>OTHER THAN SAYING HAPPY
NEW

36
00:01:41,360 --> 00:01:43,000
YEAR TO EVERYONE.

37
00:01:43,000 --> 00:01:43,680
IT'S BEEN TOO LONG.

38
00:01:43,680 --> 00:01:45,320
>>THANK YOU, VERY MUCH.

39
00:01:45,320 --> 00:01:55,800
>>ALL RIGHT, SO, I'M
GOING TO

40
00:01:57,360 --> 00:01:58,600
REVIEW OUR CHARGE AND THIS IS

41
00:01:58,600 --> 00:02:00,800
ALSO AVAILABLE ON-LINE.

42
00:02:00,800 --> 00:02:02,240
SO THIS SUBCOMMITTEE, THE

43
00:02:02,240 --> 00:02:03,720
PURPOSE OF THE SUBCOMMITTEE IS

44
00:02:03,720 --> 00:02:10,600
TO ADVISE THE NCAB AND THE

45
00:02:10,600 --> 00:02:13,480
DIRECTOR NCI ON STRATEGIC

46
00:02:13,480 --> 00:02:18,040
APPROACHES AND OPPORTUNITIES TOO

47
00:02:18,040 --> 00:02:19,920
ENHANCE NCI'S CONTRIBUTION TO

48
00:02:19,920 --> 00:02:22,000
POPULATION SCIENCE, EPIDEMIOLOGY

49
00:02:22,000 --> 00:02:24,640
AND DISPARITIES.

50
00:02:24,640 --> 00:02:27,520
THE SUBCOMMITTEE WILL BE

51
00:02:27,520 --> 00:02:30,120
RESPONSIBLE FOR IDENTIFYING

52
00:02:30,120 --> 00:02:32,440
OPPORTUNITIES TO ADDRESS

53
00:02:32,440 --> 00:02:35,080
POPULATIONS FACING DISPARITY.

54
00:02:35,080 --> 00:02:36,400
THE MULTI-DISCIPLINARY PROGRAMS

55
00:02:36,400 --> 00:02:38,640
AND RESEARCH, SURVEILLANCE,

56
00:02:38,640 --> 00:02:40,840
PATIENT CARE, PRIMARY

57
00:02:40,840 --> 00:02:44,240
PREVENTION, EDUCATION AND CANCER

58
00:02:44,240 --> 00:02:44,720
CONTROL.

59
00:02:44,720 --> 00:02:47,400
I CAN TELL YOU A LITTLE BIT

60
00:02:47,400 --> 00:02:49,360
ABOUT THE TWO THINGS THAT WE

61
00:02:49,360 --> 00:02:51,920
HAVE TACKLED SO FAR.

62
00:02:51,920 --> 00:02:55,480
THE FIRST WAS THAT WE STUDIED

63
00:02:55,480 --> 00:02:59,960
THE COHORTS, THE NCI COHORTS AND

64
00:02:59,960 --> 00:03:06,400
WE ISSUED A REPORT THAT THEN

65
00:03:06,400 --> 00:03:09,200
HELPED THE NCI WHEN THEY

66
00:03:09,200 --> 00:03:12,440
REISSUED THE COHORT RFA AND

67
00:03:12,440 --> 00:03:13,640
HELPING THEM FOCUS THEIR

68
00:03:13,640 --> 00:03:14,440
ACTIVITIES.

69
00:03:14,440 --> 00:03:17,360
ONE OF THE MAIN ISSUES THAT WAS

70
00:03:17,360 --> 00:03:22,840
CITED IN THAT REPORT WAS THAT

71
00:03:22,840 --> 00:03:25,600
THERE WAS OF A LACK OF MINORITY

72
00:03:25,600 --> 00:03:27,520
COHORTS AND SO FOR EXAMPLE, ONE

73
00:03:27,520 --> 00:03:28,680
COHORT THAT HAS BEEN FUNDED

74
00:03:28,680 --> 00:03:30,560
SINCE THEN IS IS THE HISPANIC

75
00:03:30,560 --> 00:03:32,440
COHORT.

76
00:03:32,440 --> 00:03:35,280
SO, A LOT OF THE RECOMMENDATIONS

77
00:03:35,280 --> 00:03:39,880
HAVE BEEN IMPLEMENTED IN VARIOUS

78
00:03:39,880 --> 00:03:41,640
WAYS AT THE NCI.

79
00:03:41,640 --> 00:03:44,400
THE SECOND TASK THAT WE TACKLED

80
00:03:44,400 --> 00:03:45,880
MOST OF YOU REMEMBER THAT, WE

81
00:03:45,880 --> 00:03:47,720
GAVE OUR REPORT AT THE LAST

82
00:03:47,720 --> 00:03:52,520
MEETING IN DECEMBER WAS TO

83
00:03:52,520 --> 00:03:54,040
ASSESS THE AMOUNT OF RESEARCH

84
00:03:54,040 --> 00:03:57,480
CONDUCTED AT THE NIH AND AT NCI

85
00:03:57,480 --> 00:04:02,080
AND THE UNDERSERVED-UNDER

86
00:04:02,080 --> 00:04:03,560
REPRESENTED GROUPS THAT THE AD

87
00:04:03,560 --> 00:04:06,280
HOC WORKING GROUP HAD

88
00:04:06,280 --> 00:04:06,560
IDENTIFIED.

89
00:04:06,560 --> 00:04:09,120
WE PUBLISHED THAT -- THAT IS

90
00:04:09,120 --> 00:04:09,440
AVAILABLE.

91
00:04:09,440 --> 00:04:14,400
WE PRESENTED THAT AND THAT

92
00:04:14,400 --> 00:04:17,960
REPORT AVAILABLE.

93
00:04:17,960 --> 00:04:19,160
ON THE WEB.

94
00:04:19,160 --> 00:04:26,040
ACTUALLY, THAT TASK WAS DECIDED

95
00:04:26,040 --> 00:04:28,360
LATE 2019 TO FOCUS ON THAT.

96
00:04:28,360 --> 00:04:30,560
I WAS ACTUALLY LOOKING BACK AT

97
00:04:30,560 --> 00:04:36,720
SOME OF MY NOTES AND IT WAS 2019

98
00:04:36,720 --> 00:04:38,560
WHEN WE LAST DECIDED WHAT WE

99
00:04:38,560 --> 00:04:42,000
WERE GOING TO FOCUS ON.

100
00:04:42,000 --> 00:04:47,760
SO, WE DIDN'T HAVE APP

101
00:04:47,760 --> 00:04:49,640
OPPORTUNITY TO TACKLE NEW AREAS.

102
00:04:49,640 --> 00:04:57,640
SO, I HAVE A FEW NOTES FROM WHAT

103
00:04:57,640 --> 00:04:58,640
WAS WRITTEN DOWN QUITE A LONG

104
00:04:58,640 --> 00:04:58,920
TIME AGO.

105
00:04:58,920 --> 00:05:04,200
I WOULD REALLY LIKE TO HEAR BACK

106
00:05:04,200 --> 00:05:05,960
FROM SOME OF YOU IN TERMS OF

107
00:05:05,960 --> 00:05:10,720
WHAT YOU THINK THIS ON

108
00:05:10,720 --> 00:05:12,800
POPULATION SCIENCES EPIDEMIOLOGY

109
00:05:12,800 --> 00:05:15,560
AND DISPARITIES SHOULD FOCUS ON.

110
00:05:15,560 --> 00:05:17,440
NOW, MARGARET MIGHT REMEMBER ONE

111
00:05:17,440 --> 00:05:20,280
OF THE REASONS THAT Dr.

112
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SHARPLESS HAD H HAD SUBCOMMITTEE

113
00:05:25,600 --> 00:05:27,600
BECAUSE MANY OF US SAID, WHERE

114
00:05:27,600 --> 00:05:30,800
IS THE POPULATION SCIENCE INPUT

115
00:05:30,800 --> 00:05:34,880
IN THIS DIRECTION OR THIS, YOU

116
00:05:34,880 --> 00:05:37,000
KNOW, CONCEPT THAT'S COME OUT?

117
00:05:37,000 --> 00:05:38,080
WHERE IS THE I AM PUT?

118
00:05:38,080 --> 00:05:46,960
INPUT?THERE WAS TIRING OF US SAG

119
00:05:46,960 --> 00:05:48,160
THE SAME THING.

120
00:05:48,160 --> 00:05:51,720
SO MARGARET AND I WERE PUT ON

121
00:05:51,720 --> 00:05:55,080
THIS SUBCOMMITTEE.

122
00:05:55,080 --> 00:05:58,840
SO, ANYWAY, WITH THAT LITTLE

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00:05:58,840 --> 00:06:02,160
BACKGROUND -- HELLO Dr.

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00:06:02,160 --> 00:06:02,600
BERGINOLI.

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00:06:02,600 --> 00:06:03,640
IT'S GOOD TO SEE YOU.

126
00:06:03,640 --> 00:06:05,320
THANK YOU FOR JOINING US, WE

127
00:06:05,320 --> 00:06:06,760
WERE JUST SAYING GOING OVER OUR

128
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CHARGE OF THIS SUBCOMMITTEE AND

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THE TWO REPORTS THAT WE'VE

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ALREADY TACKLED AND WE'RE OPEN

131
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TO KIND OF DISCUSSING WHAT WE

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WANTED TO DO NEXT.

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>>GREAT.

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00:06:22,160 --> 00:06:23,640
I HOPE IT'S OK THAT I DROPPED

135
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IN.

136
00:06:23,800 --> 00:06:25,360
>>DO YOU HAVE ANYTHING TO
SAY?

137
00:06:25,360 --> 00:06:26,440
>>NO, NO.

138
00:06:26,440 --> 00:06:27,800
THIS IS YOUR MEETING RIGHT NOW.

139
00:06:27,800 --> 00:06:28,440
>>THANK YOU.

140
00:06:28,440 --> 00:06:29,880
WE'RE HAPPY YOU ARE HERE WITH

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US.

142
00:06:30,760 --> 00:06:32,800
>>MARGARET, PLEASE.

143
00:06:32,800 --> 00:06:35,280
>>IF YOU RECALL WE
BROUGHT UP

144
00:06:35,280 --> 00:06:40,280
SEVERAL TIMES STARTING WHEN THE

145
00:06:40,280 --> 00:06:45,240
ISSUE OF FUNDING FOR TRAINING OF

146
00:06:45,240 --> 00:06:47,360
POPULATION SCIENTISTS, SEVERAL

147
00:06:47,360 --> 00:06:48,520
PROGRAMS THAT WE IN THE CANCER

148
00:06:48,520 --> 00:06:50,520
SCENES IS IS USED TO USE IS SUCH

149
00:06:50,520 --> 00:06:55,040
AS THE KO7 AND THE R25 WERE NO

150
00:06:55,040 --> 00:06:58,360
LONGER AVAILABLE SO WE HAD

151
00:06:58,360 --> 00:06:59,800
DISCUSSED SEVERAL TIMES THE NEED

152
00:06:59,800 --> 00:07:07,520
FOR SPECIFIC FUNDING FOR

153
00:07:07,520 --> 00:07:09,600
EDUCATIONAL PROGRAMS AND

154
00:07:09,600 --> 00:07:10,480
ELEKTRA, YOU WERE ON, I DON'T

155
00:07:10,480 --> 00:07:13,880
KNOW IF YOU STILL ARE ON THE

156
00:07:13,880 --> 00:07:16,280
SECRET FUNDING REVIEW BOARD AND

157
00:07:16,280 --> 00:07:20,680
YOU KNOW THERE THAT WE MANAGED

158
00:07:20,680 --> 00:07:21,680
TO PERSUADE THEM TO FUND THESE

159
00:07:21,680 --> 00:07:23,200
PROGRAMS BUT IT'S AN ISSUE WE IS

160
00:07:23,200 --> 00:07:26,520
SHOULD REVISIT.

161
00:07:26,520 --> 00:07:35,200
>>YES, I REMEMBER.

162
00:07:35,200 --> 00:07:37,000
WE HAD THE GENTLEMAN FROM THE

163
00:07:37,000 --> 00:07:38,480
TRAINING BRANCH COME AND TALK TO

164
00:07:38,480 --> 00:07:39,080
US A LITTLE BIT.

165
00:07:39,080 --> 00:07:40,840
HE SAID THEY WERE DOING THIS AND

166
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THAT AND WE SAID, WELL, A.,

167
00:07:43,040 --> 00:07:48,080
WE'LL GIVE YOU TIME AND WE WANT

168
00:07:48,080 --> 00:07:49,800
TO REVISIT HOW THAT HAS IMPACTED

169
00:07:49,800 --> 00:07:55,640
POPULATIONS SCIENCES.

170
00:07:55,640 --> 00:07:56,280
CHRIS MAR --

171
00:07:56,280 --> 00:08:04,880
CHRISTOPHER -->>BUILDING
ON MAS

172
00:08:04,880 --> 00:08:05,160
COMMENTS.

173
00:08:05,160 --> 00:08:07,720
WE HAVE A GOOD UNDERSTANDING

174
00:08:07,720 --> 00:08:09,080
RELATIVE TO OTHER AREAS IN

175
00:08:09,080 --> 00:08:10,600
CANCER RESEARCH, WHAT THE

176
00:08:10,600 --> 00:08:12,800
LANDSCAPE IS FOR POPULATION

177
00:08:12,800 --> 00:08:13,600
SCIENCE TRAINING AND WORKFORCE.

178
00:08:13,600 --> 00:08:14,840
WE HAVE A BETTER SENSE OF THAT

179
00:08:14,840 --> 00:08:16,440
FOR THE CLINICIAN WORKFORCE AND

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00:08:16,440 --> 00:08:20,240
WE KNOW THERE ARE GAPS.

181
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IF WE REALLY BELIEVE POPULATION

182
00:08:21,520 --> 00:08:25,320
SCIENCE IS A BEDROCK OF CONTROL

183
00:08:25,320 --> 00:08:26,640
OUT EVERYBODY IN THIS MEETING

184
00:08:26,640 --> 00:08:28,520
WOULD AGREE WITH ME ON THAT, WE

185
00:08:28,520 --> 00:08:30,320
DON'T REALLY HAVE A GOOD SENSE

186
00:08:30,320 --> 00:08:32,720
THAT HAVE AND WE DON'T HAVE A

187
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SENSE OF WHERE NCI CAN NIL AND

188
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SPECIFICALLY, JUST AS ONE

189
00:08:37,280 --> 00:08:39,080
EXAMPLE, I REMEMBER SUSAN AND I

190
00:08:39,080 --> 00:08:40,000
HAD A GREAT CONVERSATION.

191
00:08:40,000 --> 00:08:41,760
THERE'S AN INCREASING NUMBER OF

192
00:08:41,760 --> 00:08:44,600
PHYSICIAN AND OTHER CLINICIANS

193
00:08:44,600 --> 00:08:47,360
WHO ARE SEEING PROBLEMS WITH

194
00:08:47,360 --> 00:08:48,520
PATIENTS AND THE POPULATIONS

195
00:08:48,520 --> 00:08:50,520
THEY SERVE AND THEY WANT

196
00:08:50,520 --> 00:08:54,560
TRAINING IN CANCER CONTROL AND

197
00:08:54,560 --> 00:08:57,200
POPULATION SCIENCE, YET OUR

198
00:08:57,200 --> 00:08:57,800
CURRENT MECHANISMS DON'T MEET

199
00:08:57,800 --> 00:08:58,680
THAT NEED.

200
00:08:58,680 --> 00:09:00,720
ONE EXAMPLE AND I COULD THINK OF

201
00:09:00,720 --> 00:09:01,920
OTHERS.

202
00:09:01,920 --> 00:09:02,720
THAT'S A WORTH WHILE EXERCISE

203
00:09:02,720 --> 00:09:07,560
FOR US IS TO A ISSUE ON THE

204
00:09:07,560 --> 00:09:09,240
LANDSCAPE OF CANCER CONTROL AND

205
00:09:09,240 --> 00:09:10,520
SCIENCE FUTURE WORKFORCE AND

206
00:09:10,520 --> 00:09:11,480
WHERE WE MIGHT SEE GAPS AND

207
00:09:11,480 --> 00:09:14,680
WHERE WE MIGHT SEE

208
00:09:14,680 --> 00:09:15,040
OPPORTUNITIES.

209
00:09:15,040 --> 00:09:15,600
>>GREAT.

210
00:09:15,600 --> 00:09:16,600
THANK YOU.

211
00:09:16,600 --> 00:09:20,120
PHIL, I BELIEVE YOU WERE NEXT.

212
00:09:20,120 --> 00:09:30,280
>>SORRY.

213
00:09:32,120 --> 00:09:33,240
THIS HAS BEEN A CONCERN FOR BOTH

214
00:09:33,240 --> 00:09:36,920
KATRINA GOODARD AND ABOUT

215
00:09:36,920 --> 00:09:39,560
POPULATION SCIENCE AND WE ARE

216
00:09:39,560 --> 00:09:41,960
DOING SORT OF A PORTFOLIO

217
00:09:41,960 --> 00:09:44,080
ANALYSIS AT THE MOMENT AND

218
00:09:44,080 --> 00:09:47,200
LOOKING AT GAPS AND TRAINING

219
00:09:47,200 --> 00:09:47,920
OPPORTUNITIES.

220
00:09:47,920 --> 00:09:53,520
I WILL SAY THAT REALLY THINKING

221
00:09:53,520 --> 00:09:56,560
ABOUT TWO DIFFERENT SETS OF

222
00:09:56,560 --> 00:10:00,200
TRAINING, THERE'S THE SORT OF

223
00:10:00,200 --> 00:10:03,120
POPULATION SCIENCE -- POPULATION

224
00:10:03,120 --> 00:10:05,080
CANCER CONTROL SCIENTIST AND

225
00:10:05,080 --> 00:10:10,680
WHAT IS NEEDED TO EXPAND THAT

226
00:10:10,680 --> 00:10:12,040
WORKFORCE AND THERE'S A SEPARATE

227
00:10:12,040 --> 00:10:15,480
GROUP WHICH IS THE

228
00:10:15,480 --> 00:10:16,480
TRANSLATIONAL.

229
00:10:16,480 --> 00:10:17,440
THEY REFLECT WHAT THE DIVISIONS

230
00:10:17,440 --> 00:10:21,240
DO AND OFTEN IT'S NOT OBVIOUS TO

231
00:10:21,240 --> 00:10:22,600
EXTRAMURAL BUT WE ARE TOO

232
00:10:22,600 --> 00:10:26,840
DISTINCT DIVISIONS WITH TWO

233
00:10:26,840 --> 00:10:28,640
DISTINCT GOALS AND WE'RE FOCUSED

234
00:10:28,640 --> 00:10:30,560
ON DISCOVERY AND THE THINGS THAT

235
00:10:30,560 --> 00:10:34,840
WORK AND WE HAND OFF TO DCCPS

236
00:10:34,840 --> 00:10:36,440
AND WE NEED WORKFORCES AND A LOT

237
00:10:36,440 --> 00:10:43,520
OF CANCER CENTERS -- KATRINA

238
00:10:43,520 --> 00:10:45,240
SENT ME A NOTE SAYING SHE'S

239
00:10:45,240 --> 00:10:47,720
DOING THIS ANALYSIS.

240
00:10:47,720 --> 00:10:49,200
WE NEED TO EXPAND THE WORKFORCE

241
00:10:49,200 --> 00:10:52,560
IN BOTH YEARS GREATLY AND TO

242
00:10:52,560 --> 00:10:54,320
DIVERSIFY IT AND WE RECOGNIZE IT

243
00:10:54,320 --> 00:10:57,120
AND WE ARE WORKING ON THAT FIRST

244
00:10:57,120 --> 00:10:59,840
REQUIRES US TO DO A FULL

245
00:10:59,840 --> 00:11:04,040
LANDSCAPE APPAL SIS BUT WE ARE

246
00:11:04,040 --> 00:11:05,440
PARTICULARLY IN THE CANCER

247
00:11:05,440 --> 00:11:06,680
PREVENTION SPACE SO WE HAVE A

248
00:11:06,680 --> 00:11:13,720
HARD TIME GETTING BIOLOGISTS

249
00:11:13,720 --> 00:11:15,480
INTERESTED IN TRANSLATIONAL

250
00:11:15,480 --> 00:11:17,520
RESEARCH TO GO INTO PREVENTION

251
00:11:17,520 --> 00:11:22,880
AND THEY GO INTO ONCOLOGY AND WE

252
00:11:22,880 --> 00:11:25,520
NEED TO BUILD A PATH FOR THEM TO

253
00:11:25,520 --> 00:11:28,080
COME INTO PREVENTION AND

254
00:11:28,080 --> 00:11:33,560
RECOGNIZE THERE'S A LOT OF

255
00:11:33,560 --> 00:11:34,000
OPPORTUNITIES AND

256
00:11:34,000 --> 00:11:35,120
THEY HAVE NCI SUPPORT.

257
00:11:35,120 --> 00:11:39,520
I DON'T WANT TO SPEAK FOR

258
00:11:39,520 --> 00:11:49,920
KATRINA BUT I KNOW WE'RE

259
00:11:50,920 --> 00:11:52,840
THINKING OF NEW RFAs IN THE

260
00:11:52,840 --> 00:11:54,160
FUTURE AND THE IT WOULD BE I AM

261
00:11:54,160 --> 00:11:55,120
HER ENTER IN THAT SO I DON'T

262
00:11:55,120 --> 00:11:56,640
WANT TO TAKE TOO MUCH OF YOUR

263
00:11:56,640 --> 00:11:59,360
TIME BUT WE SHARE YOUR INTEREST

264
00:11:59,360 --> 00:12:00,400
AND CONCERN AND THE NEED TO

265
00:12:00,400 --> 00:12:05,280
BUILD OUT THE WORKFORCE FOR THE

266
00:12:05,280 --> 00:12:15,680
NEXT GENERATION.

267
00:12:15,680 --> 00:12:17,080
>>WE WOULD ADD TO WHAT
YOU ARE

268
00:12:17,080 --> 00:12:19,720
DOING OR DO YOU THINK THAT THE

269
00:12:19,720 --> 00:12:21,400
LANDSCAPE PORTFOLIO ANALYSIS

270
00:12:21,400 --> 00:12:24,080
THAT YOU BOTH ARE DOING WOULD BE

271
00:12:24,080 --> 00:12:27,800
ENOUGH OR WHAT CAN WE ADD?

272
00:12:27,800 --> 00:12:33,400
>>WELL, I'D LIKE TO
CONDUCT IS

273
00:12:33,400 --> 00:12:35,040
WE -- IF WE CAN GET ON THE

274
00:12:35,040 --> 00:12:36,000
DOCKET AND PRESENT WHAT WE'VE

275
00:12:36,000 --> 00:12:37,960
LEARNED SO FAR AND GET YOUR

276
00:12:37,960 --> 00:12:42,920
INPUT ABOUT YOU KNOW, IF WE

277
00:12:42,920 --> 00:12:45,800
MILLED SOMETHING AND ALSO TO GET

278
00:12:45,800 --> 00:12:48,720
YOUR IDEAS ABOUT HOW TO DEPLOY

279
00:12:48,720 --> 00:12:51,880
OUR CREATE THOSE TRAINING

280
00:12:51,880 --> 00:12:54,160
OPPORTUNITIES SO THAT WE CAN

281
00:12:54,160 --> 00:12:57,400
ACHIEVE THE GOAL THAT WE ALL

282
00:12:57,400 --> 00:12:58,560
ASPIRE TO.

283
00:12:58,560 --> 00:13:00,360
I THINK THAT'S WHAT I WOULD

284
00:13:00,360 --> 00:13:01,960
SUGGEST IS GIVE US THREE MORE

285
00:13:01,960 --> 00:13:03,080
MONTHS.

286
00:13:03,080 --> 00:13:04,760
I JUST THIRD A STRATEGIC

287
00:13:04,760 --> 00:13:06,280
PLANNING OFFICER AND SHE'S BEEN

288
00:13:06,280 --> 00:13:09,000
TASKED TO DO THAT AND SHE'S GOT

289
00:13:09,000 --> 00:13:10,200
GOOD ROOTS IN THIS AREA BECAUSE

290
00:13:10,200 --> 00:13:11,840
THEY WERE THE DEPUTY DIRECTING

291
00:13:11,840 --> 00:13:13,200
OFFER OUR CANCER DEVELOPMENT

292
00:13:13,200 --> 00:13:14,600
PROGRAM AND WE'RE EXPANDING ALL

293
00:13:14,600 --> 00:13:21,880
OF THAT AND THERE'S A LOT OF

294
00:13:21,880 --> 00:13:23,200
PIECES WE CAN PRESENT IN SORT OF

295
00:13:23,200 --> 00:13:24,480
THE FULL SCOPE OF WHAT WE'RE

296
00:13:24,480 --> 00:13:26,720
THINKING AND WHAT WE'RE TRYING

297
00:13:26,720 --> 00:13:30,000
TO DO.

298
00:13:30,000 --> 00:13:36,040
FOR EXAMPLE, WE STARTED TO HAVE

299
00:13:36,040 --> 00:13:38,320
ONE OF OUR CANCER PREVENTION

300
00:13:38,320 --> 00:13:40,600
FELLOWS DETAIL OR ROTATE SO THAT

301
00:13:40,600 --> 00:13:44,800
WE'RE CREATING A POLICY

302
00:13:44,800 --> 00:13:49,240
FELLOWSHIP AND WHICH IS PART OF

303
00:13:49,240 --> 00:13:50,040
POPULATION CONTROL AND WE'RE

304
00:13:50,040 --> 00:13:51,920
THINKING ABOUT AN INTERNATIONAL

305
00:13:51,920 --> 00:13:52,960
COMPONENT TO THE CANCER

306
00:13:52,960 --> 00:13:54,480
PREVENTION FELLOWSHIP AND THINGS

307
00:13:54,480 --> 00:13:58,200
LIKE THAT SO I'D LIKE TO SUGGEST

308
00:13:58,200 --> 00:14:00,040
WE BRING A FULL STORY OR AT

309
00:14:00,040 --> 00:14:02,240
LEAST WHERE WE ARE AFTER THE

310
00:14:02,240 --> 00:14:03,320
NEXT YOU KNOW IN THREE MONTHS

311
00:14:03,320 --> 00:14:04,640
FROM NOW WHEN WE GET TOGETHER

312
00:14:04,640 --> 00:14:06,160
THIS SUMMER.

313
00:14:06,160 --> 00:14:16,520
>>THAT WILL BE JUNE.

314
00:14:18,240 --> 00:14:19,640
>>ARE YOU WEAVING UNDER

315
00:14:19,640 --> 00:14:20,840
POPULATION PLANS IN THIS

316
00:14:20,840 --> 00:14:21,080
TRAINING?

317
00:14:21,080 --> 00:14:21,720
>>ABSOLUTELY.

318
00:14:21,720 --> 00:14:22,440
>>WONDERFUL.

319
00:14:22,440 --> 00:14:24,840
>>AND THAT GOES EVEN INTO
THE

320
00:14:24,840 --> 00:14:26,200
INTERNATIONAL COMPONENT OF THE

321
00:14:26,200 --> 00:14:34,360
CANCER PREVENTION FELLOWSHIP AND

322
00:14:34,360 --> 00:14:35,760
THERE ARE CHALLENGES FOR

323
00:14:35,760 --> 00:14:36,760
INTERNATIONAL FELLOWS TO COME TO

324
00:14:36,760 --> 00:14:39,360
THE NCI IS SOMETHING THAT I CAME

325
00:14:39,360 --> 00:14:40,400
IN SAYING WE'VE GOT TO FIGURE

326
00:14:40,400 --> 00:14:50,880
OUT A WAY TO DO THIS SO THE

327
00:14:53,840 --> 00:14:57,960
STORY IS MATURE ENOUGH TO

328
00:14:57,960 --> 00:14:58,840
PRESENTED TO YOU AND GET YOUR

329
00:14:58,840 --> 00:14:59,760
FEEDBACK IF THAT'S OK.

330
00:14:59,760 --> 00:15:00,480
>>THAT'S GREAT.

331
00:15:00,480 --> 00:15:02,520
SUSAN AND KAREN, I DIDN'T KNOW

332
00:15:02,520 --> 00:15:12,840
WHO CAME UP FIRST.

333
00:15:16,240 --> 00:15:18,600
>>THE REPORT THAT WAS
DONE IT

334
00:15:18,600 --> 00:15:20,200
WAS LOOKED AT PORTFOLIO OF

335
00:15:20,200 --> 00:15:20,640
RESEARCH.

336
00:15:20,640 --> 00:15:22,240
THE WORKFORCE IS IMPORTANT.

337
00:15:22,240 --> 00:15:23,800
I LOVE THIS AND LOVE WHERE YOU

338
00:15:23,800 --> 00:15:24,520
ARE GOING.

339
00:15:24,520 --> 00:15:26,760
ONE THING THAT CAME UP AT THE

340
00:15:26,760 --> 00:15:29,240
AACR MEETING WAS PERHAPS

341
00:15:29,240 --> 00:15:32,720
THINKING ABOUT SOME GUIDANCE

342
00:15:32,720 --> 00:15:36,480
AROUND WHAT DOES THE SOCIAL

343
00:15:36,480 --> 00:15:38,160
DETERMINANTS AND IF WE CAN WEIGH

344
00:15:38,160 --> 00:15:40,920
IN ON THAT OR PROVIDE GUIDANCE

345
00:15:40,920 --> 00:15:43,280
BUT THERE NEEDS TO BE FOR PEOPLE

346
00:15:43,280 --> 00:15:46,160
TO MOVE FORWARD IN THIS SPACE, I

347
00:15:46,160 --> 00:15:47,960
THINK A LOT OF THE SCRIPTERS AND

348
00:15:47,960 --> 00:15:50,120
RACE AND ETHNICITY ARE FINE AND

349
00:15:50,120 --> 00:15:51,440
A LOT OF THIS GIRLS DOWN TO

350
00:15:51,440 --> 00:15:52,960
SOCIAL DETERMINANTS OF HEALTH

351
00:15:52,960 --> 00:15:55,080
AND I DO WONDER IF IT IT MAKING

352
00:15:55,080 --> 00:15:56,920
SOMETHING IF IT'S A BIG THING TO

353
00:15:56,920 --> 00:15:59,280
TACKLE BUT THERE NEEDS TO BE

354
00:15:59,280 --> 00:16:09,800
SOMEWAY TO CREATE A UNIFIED ON

355
00:16:12,360 --> 00:16:16,160
POPULATION HEALTH.

356
00:16:16,160 --> 00:16:17,920
>>HAVING A COMMON
LANGUAGE WE

357
00:16:17,920 --> 00:16:19,760
ALL SPEAK AND WHEN WE SAY, YELL

358
00:16:19,760 --> 00:16:22,200
OH WE ALL RECOGNIZE WHAT THE

359
00:16:22,200 --> 00:16:23,400
COLOR YELLOW IS IS.

360
00:16:23,400 --> 00:16:25,840
THAT'S A BIG CHALLENGE IN MANY

361
00:16:25,840 --> 00:16:29,200
OF OUR SPECIALTIES LET ALONE

362
00:16:29,200 --> 00:16:30,240
TALKING ABOUT SOCIAL

363
00:16:30,240 --> 00:16:31,440
DETERMINANTS OF HEALTH.

364
00:16:31,440 --> 00:16:35,040
COMING UP WITH CODIFIED

365
00:16:35,040 --> 00:16:36,440
VOCABULARY WOULD BE VERY, VERY

366
00:16:36,440 --> 00:16:39,520
HELPFUL EX COMMUNICATING BROADLY

367
00:16:39,520 --> 00:16:42,640
SO I TOTALLY ENDORSE IT.

368
00:16:42,640 --> 00:16:44,360
>>THANK YOU, KAREN.

369
00:16:44,360 --> 00:16:48,000
I DO HAVE A QUESTION ON THAT BUT

370
00:16:48,000 --> 00:16:50,440
SUSAN, ARE YOU IN THE SAME AREA

371
00:16:50,440 --> 00:16:52,480
OR DO YOU WANT TO TALK ABOUT

372
00:16:52,480 --> 00:16:52,920
SOMETHING ELSE?

373
00:16:52,920 --> 00:16:54,360
>>SAME AREA AND TALK
ABOUT

374
00:16:54,360 --> 00:16:54,920
SOMETHING ELSE.

375
00:16:54,920 --> 00:16:55,920
>>GO AHEAD.

376
00:16:55,920 --> 00:17:03,200
>>SO, WHEN THE NCI WAS
STRUGGLE

377
00:17:03,200 --> 00:17:09,200
TO GO DECIDE HOW IT TO APPROACH

378
00:17:09,200 --> 00:17:15,480
ROLL, THEY CONVENED A YEAR LONG

379
00:17:15,480 --> 00:17:16,560
SET OF MEETINGS.

380
00:17:16,560 --> 00:17:18,880
A SMALL GROUP OF FOLKS AND THEY

381
00:17:18,880 --> 00:17:21,480
HAD A LOT OF PEOPLE COME IN,

382
00:17:21,480 --> 00:17:23,880
WHAT IS RURAL, HOW DO WE DEFINE

383
00:17:23,880 --> 00:17:24,360
RURAL?

384
00:17:24,360 --> 00:17:25,960
IT TOOK ALMOST A YEAR BUT THEN

385
00:17:25,960 --> 00:17:30,000
YOU KNOW, THAT DEFINITION IS

386
00:17:30,000 --> 00:17:33,600
SORT OF WHAT'S ACCEPTED BY NCI.

387
00:17:33,600 --> 00:17:35,000
THERE WERE A LOT OF DEFINITIONS

388
00:17:35,000 --> 00:17:39,640
OF RURAL OUT THERE AND NCI

389
00:17:39,640 --> 00:17:41,600
DIDN'T KNOW WHICH ONE TO USE.

390
00:17:41,600 --> 00:17:47,200
THEY COULDN'T START CU STARTINGG

391
00:17:47,200 --> 00:17:48,560
THE NUMBERS AND SHOW US WHEN

392
00:17:48,560 --> 00:17:52,760
THEY DID AND THEY WERE A GREAT

393
00:17:52,760 --> 00:17:53,040
DISPARITY.

394
00:17:53,040 --> 00:17:56,200
THIS IS ALMOST ALONG TO VANE TO

395
00:17:56,200 --> 00:17:56,920
MY MIND.

396
00:17:56,920 --> 00:17:58,600
THERE'S A LOT OF THINGS OUT

397
00:17:58,600 --> 00:18:01,360
THERE AND PEOPLE ARE CALLING

398
00:18:01,360 --> 00:18:02,720
SOCIAL DETERMINANTS OF HEALTH AS

399
00:18:02,720 --> 00:18:08,800
LIKE THE NEW BUZZWORD AND WHAT

400
00:18:08,800 --> 00:18:10,200
WE TALKING ABOUT SOCIAL

401
00:18:10,200 --> 00:18:12,240
DETERMINANTS OF HEALTH AND THEN

402
00:18:12,240 --> 00:18:14,200
HOW DO WE A SUNSHINE THEM

403
00:18:14,200 --> 00:18:18,240
UNIFORMLY AND HOW DO WE LIKE YOU

404
00:18:18,240 --> 00:18:21,000
SAID, ASSESS THE IMPACT ON

405
00:18:21,000 --> 00:18:23,560
OUTCOMES AND HEALTH.

406
00:18:23,560 --> 00:18:26,760
SO, ANYWAY, THAT'S JUST SORT OF

407
00:18:26,760 --> 00:18:29,200
MY HISTORY WITH NCI IN TERMS OF

408
00:18:29,200 --> 00:18:35,280
WHEN THEY WANT SORT OF COME ON A

409
00:18:35,280 --> 00:18:37,160
DEFINITION AND I'M HAPPY IF WE

410
00:18:37,160 --> 00:18:39,840
DECIDE WE WANT TO DO THIS O IF

411
00:18:39,840 --> 00:18:41,360
THIS IS SOMETHING DONE IN THE

412
00:18:41,360 --> 00:18:46,040
SAME FRAME THAT THEY PROCEEDED

413
00:18:46,040 --> 00:18:46,840
FOR RURAL.

414
00:18:46,840 --> 00:18:49,240
I'M HAPPY TO -- HOWEVER.

415
00:18:49,240 --> 00:18:51,520
SO ON THE TABLE.

416
00:18:51,520 --> 00:18:52,880
THANK YOU.

417
00:18:52,880 --> 00:18:54,480
SUSAN, GO AHEAD AND THEN ADD AND

418
00:18:54,480 --> 00:18:56,000
ADD ANOTHER ONE.

419
00:18:56,000 --> 00:18:56,440
>>SOUNDS GOOD.

420
00:18:56,440 --> 00:18:58,840
THANK YOU, ELECTRA.

421
00:18:58,840 --> 00:19:01,120
SO, PHIL, I JUST WANTED GO BACK

422
00:19:01,120 --> 00:19:03,080
TO THE LANDSCAPE ANALYSIS THAT

423
00:19:03,080 --> 00:19:07,360
YOU AND KATRINA AND OTHERS ARE

424
00:19:07,360 --> 00:19:09,200
WORKING ON.

425
00:19:09,200 --> 00:19:11,520
WILL THATTEN COMPASS SOME

426
00:19:11,520 --> 00:19:13,680
ASSESSMENT OF THE T32s FOCUSED

427
00:19:13,680 --> 00:19:15,000
ON TOP SIDE.

428
00:19:15,000 --> 00:19:16,400
SEVERAL OF US LEAD THEM AND I

429
00:19:16,400 --> 00:19:18,400
FEEL LIKE IT'S SUCH A PIPELINE

430
00:19:18,400 --> 00:19:20,400
AND THAT'S ALSO AN AREA TO

431
00:19:20,400 --> 00:19:22,000
IDENTIFY GAPS, YOU KNOW, SO IF

432
00:19:22,000 --> 00:19:25,280
YOU SEE A LOT ARE FOCUSED ON X

433
00:19:25,280 --> 00:19:29,880
BUT NOTHING HAS POP-SI AND DATA

434
00:19:29,880 --> 00:19:31,720
SCIENCE AND MAYBE THAT'S AN

435
00:19:31,720 --> 00:19:32,800
OPPORTUNITY TO HELP US THINK

436
00:19:32,800 --> 00:19:35,720
ABOUT HOW DO WE GET OUR EARLY

437
00:19:35,720 --> 00:19:38,320
INVESTIGATORS COMPETITIVE IN

438
00:19:38,320 --> 00:19:40,520
CANCER PREVENTION AND CONTROL

439
00:19:40,520 --> 00:19:42,040
WORK TODAY.

440
00:19:42,040 --> 00:19:43,560
SO THAT A SUGGESTION OR IF YOU

441
00:19:43,560 --> 00:19:45,240
ALREADY THOUGHT OF, I'M GLAD AND

442
00:19:45,240 --> 00:19:49,040
THE OTHER THING IS -- I WAS ALSO

443
00:19:49,040 --> 00:19:50,680
WONDERING, AND I HOPE YOU GUYS

444
00:19:50,680 --> 00:19:53,400
MAKE SURE TO TAKE CREDIT FOR

445
00:19:53,400 --> 00:19:55,640
SOME THE INNOVATIVE THINGS YOU

446
00:19:55,640 --> 00:19:58,240
DO TO RESPOND TO EMERGING AREAS.

447
00:19:58,240 --> 00:19:59,480
I'M THINKING ABOUT THE

448
00:19:59,480 --> 00:20:01,200
MULTI-LEVEL TRAINING INSTITUTE,

449
00:20:01,200 --> 00:20:03,720
THE IMPLEMENTATION SCIENCE

450
00:20:03,720 --> 00:20:05,480
INSTITUTE, THE DISSEMINATION

451
00:20:05,480 --> 00:20:05,920
ONE.

452
00:20:05,920 --> 00:20:06,800
YOU'VE TRAINED A LOT OF PEOPLE

453
00:20:06,800 --> 00:20:08,440
WHO ARE TRYING TO EARLY PEOPLE

454
00:20:08,440 --> 00:20:11,280
WHO ARE TRYING TO GET A LITTLE

455
00:20:11,280 --> 00:20:14,600
BIT MORE TRAINING AND COMFORT IN

456
00:20:14,600 --> 00:20:17,720
AN AREA AND I PERSONALLY HAVE

457
00:20:17,720 --> 00:20:18,720
PARTICIPATED IN SEVERAL OF THEM

458
00:20:18,720 --> 00:20:21,000
SO I THINK IT'S A GREAT MODEL

459
00:20:21,000 --> 00:20:23,320
FOR ADDRESSING EMERGING AREAS

460
00:20:23,320 --> 00:20:25,040
FOR NEW INVESTIGATORS.

461
00:20:25,040 --> 00:20:27,480
IT DOESN'T HELP WITH THE

462
00:20:27,480 --> 00:20:29,040
KO7-TYPE OF ISSUE BUT I REALLY

463
00:20:29,040 --> 00:20:31,920
DO THINK THAT THAT'S SUCH A

464
00:20:31,920 --> 00:20:33,320
VALUABLE THING THAT YOU ALL HAVE

465
00:20:33,320 --> 00:20:37,320
CUP AND IT SDONE AND IT SHOULD F

466
00:20:37,320 --> 00:20:38,840
WHAT YOU TAKE CREDIT FOR AND

467
00:20:38,840 --> 00:20:43,040
SOMETHING YOU TRANSLATE I LATE

468
00:20:43,040 --> 00:20:44,400
INTERNATIONALLY AS YOU REACH

469
00:20:44,400 --> 00:20:46,120
FURTHER POPULATIONS SO JUST SOME

470
00:20:46,120 --> 00:20:47,880
SUGGESTIONS FOR THAT.

471
00:20:47,880 --> 00:20:48,840
>>GREAT COMMENTS.

472
00:20:48,840 --> 00:20:49,600
>>EXCELLENT.

473
00:20:49,600 --> 00:20:51,240
>>TWO EXCELLENT
SUGGESTIONS.

474
00:20:51,240 --> 00:20:51,560
>>YES.

475
00:20:51,560 --> 00:20:53,400
>>DO YOU WANT TO ADD
ANYTHING?

476
00:20:53,400 --> 00:20:56,840
>>YEAH.

477
00:20:56,840 --> 00:21:03,520
>>I WANT TODAY GO BACK TO
THE

478
00:21:03,520 --> 00:21:04,600
SOCIAL DETERMINANTS OF HEALTH

479
00:21:04,600 --> 00:21:07,200
AND I LIKE THIS IDEA OF THIS

480
00:21:07,200 --> 00:21:09,000
GROUP HELPING TO FRAME THAT IF

481
00:21:09,000 --> 00:21:12,760
THAT'S USEFUL AND TO TAKE IT A

482
00:21:12,760 --> 00:21:14,400
STEP FURTHER, OF THE HARD PARTS,

483
00:21:14,400 --> 00:21:15,120
RIGHT.

484
00:21:15,120 --> 00:21:20,480
SO WE WORK WITH UNDERSERVED

485
00:21:20,480 --> 00:21:20,760
POPULATIONS.

486
00:21:20,760 --> 00:21:22,560
A LOT OF US DO RESEARCH IN THIS

487
00:21:22,560 --> 00:21:24,720
AREA BUT WHERE THE RUBBER MEETS

488
00:21:24,720 --> 00:21:26,680
THE ROAD IS NEXT STEP.

489
00:21:26,680 --> 00:21:27,880
WHETHER IT'S PEOPLE THAT

490
00:21:27,880 --> 00:21:30,800
PARTICIPATE IN OUR RESEARCH

491
00:21:30,800 --> 00:21:32,000
STUDIES, FOR THOSE OF US THAT

492
00:21:32,000 --> 00:21:35,360
LEAD COE TEAMS, YOU KNOW, I

493
00:21:35,360 --> 00:21:37,000
DON'T KNOW, HEARING FROM EACH

494
00:21:37,000 --> 00:21:39,680
OTHER, BEST PRACTICES,

495
00:21:39,680 --> 00:21:42,760
STRATEGIES, OR GAPS IN THIS AREA

496
00:21:42,760 --> 00:21:46,520
OF YOU KNOW, BY DEFINITION

497
00:21:46,520 --> 00:21:48,120
POP-SI RESEARCH TOUCHES PEOPLE

498
00:21:48,120 --> 00:21:50,040
AND YOU ARE ASKING THEM TO

499
00:21:50,040 --> 00:21:52,120
ENGAGE IN SOMETHING, DO

500
00:21:52,120 --> 00:21:53,560
SOMETHING AND THEN YOU KNOW, WE

501
00:21:53,560 --> 00:21:57,600
ARE ALL KIND OF LEFT TO

502
00:21:57,600 --> 00:22:00,520
OURSELVES TO FIGURE OUT SOCIAL

503
00:22:00,520 --> 00:22:01,600
DETERMINANTS OF HEALTH WHEN

504
00:22:01,600 --> 00:22:03,200
ACCESS IS AN ISSUE SO EVEN IF WE

505
00:22:03,200 --> 00:22:04,680
HIGHLIGHT AND BRING THAT TO

506
00:22:04,680 --> 00:22:07,120
LIGHT IT'S ANOTHER SORT OF

507
00:22:07,120 --> 00:22:08,640
PIGGYBACK OFF OF WHAT WAS JUST

508
00:22:08,640 --> 00:22:09,040
DISCUSSED.

509
00:22:09,040 --> 00:22:10,120
SO THAT'S IT FOR ME.

510
00:22:10,120 --> 00:22:11,400
>>THANK YOU, SUSAN.

511
00:22:11,400 --> 00:22:13,240
A LOT OF THE SECOND PART OF WHAT

512
00:22:13,240 --> 00:22:16,400
WE WERE TALKING ABOUT ARE AS YOU

513
00:22:16,400 --> 00:22:18,360
KNOW UNFUNDED MANDATES THAT WE

514
00:22:18,360 --> 00:22:19,160
TAKE.

515
00:22:19,160 --> 00:22:20,680
KAREN, YOU KNOW THAT VERY WELL

516
00:22:20,680 --> 00:22:21,040
TOO.

517
00:22:21,040 --> 00:22:25,400
AND IT'S THE COEs THAT WE DO A

518
00:22:25,400 --> 00:22:27,200
LOT OF UNFUNDED MANDATES.

519
00:22:27,200 --> 00:22:37,200
IT SEEMS LIKE THE MANDATES ARE

520
00:22:37,200 --> 00:22:40,560
BECAUSE IT'S THE RIGHT THING TO

521
00:22:40,560 --> 00:22:42,240
DO AND WE WANT TO DO THE RIGHT

522
00:22:42,240 --> 00:22:43,360
THING FOR THESE POPULATIONS,

523
00:22:43,360 --> 00:22:43,560
YEAH.

524
00:22:43,560 --> 00:22:45,360
THANK YOU, SUSAN.

525
00:22:45,360 --> 00:22:46,480
PHIL, DO YOU WANT TO RESPOND ON

526
00:22:46,480 --> 00:22:49,800
THE INCLUSION OF THE T32s IN

527
00:22:49,800 --> 00:22:54,680
YOUR LANDSCAPE ANALYSIS?

528
00:22:54,680 --> 00:22:58,760
>>IT'S A GREAT IDEA.

529
00:22:58,760 --> 00:23:00,280
MY FOCUS I DON'T WANT TO SPEAK

530
00:23:00,280 --> 00:23:02,040
TOO MUCH FOR KATRINE AND IT'S ON

531
00:23:02,040 --> 00:23:04,160
THE K AWARD AS WHEN THE K AWARD

532
00:23:04,160 --> 00:23:07,800
GOT SORT OF CONSOLIDATED AND I

533
00:23:07,800 --> 00:23:11,280
THINK DID A DISSERVICE AND

534
00:23:11,280 --> 00:23:11,920
THERE'S A CONFLATION OF PEOPLE

535
00:23:11,920 --> 00:23:13,480
TALK ABOUT CANCER PREVENTION AND

536
00:23:13,480 --> 00:23:17,360
IT'S REALLY SORT OF TWO SETS OF

537
00:23:17,360 --> 00:23:22,000
TRAINEES THERE'S THE SORT OF THE

538
00:23:22,000 --> 00:23:24,240
EPI SLASH THE FOLKS INTERESTED

539
00:23:24,240 --> 00:23:29,040
IN CANCER CONTROL AND THAT'S

540
00:23:29,040 --> 00:23:30,560
TYPICALLY WHAT CANCER CENTERS

541
00:23:30,560 --> 00:23:36,120
FOCUS ON BUT WE'RE FACED WITH A

542
00:23:36,120 --> 00:23:37,440
REAL CHALLENGE OF GETTING

543
00:23:37,440 --> 00:23:42,600
BIOLOGISTS AND TECHNOLOGIES

544
00:23:42,600 --> 00:23:44,560
INTERESTED IN CANCER PREVENTION

545
00:23:44,560 --> 00:23:46,960
AND TRANSLATIONAL RESEARCH AND

546
00:23:46,960 --> 00:23:47,560
WE'RE BEING CHOKED OFF HERE BY

547
00:23:47,560 --> 00:23:52,920
NOT GETTING ENOUGH NOT JUST

548
00:23:52,920 --> 00:23:56,840
ENOUGH WARM BODIES BUT IT'S PART

549
00:23:56,840 --> 00:23:58,760
OF IT BUT SOME NEW IDEAS AND

550
00:23:58,760 --> 00:24:02,840
WAYS OF THINKING ABOUT THINGS

551
00:24:02,840 --> 00:24:05,120
AND WE NEED SOME OUTSIDE BOX

552
00:24:05,120 --> 00:24:06,320
KINDS OF IDEAS AND IF WE'RE

553
00:24:06,320 --> 00:24:08,400
GOING TO MAKE SOME REAL PROGRESS

554
00:24:08,400 --> 00:24:13,480
AND SO I REALLY WANT TO KIND OF

555
00:24:13,480 --> 00:24:14,040
CATALYZE.

556
00:24:14,040 --> 00:24:19,560
YOU KNOW, EPIDEMIOLOGY T32 IS

557
00:24:19,560 --> 00:24:20,840
THAT EVEN GOING EARLY ENOUGH AND

558
00:24:20,840 --> 00:24:27,560
I DON'T KNOW HOW EARLY WE CAN GO

559
00:24:27,560 --> 00:24:30,680
BUT -- I DIDN'T THINK ABOUT

560
00:24:30,680 --> 00:24:31,400
EPIDEMIOLOGY WHEN I LEARNED

561
00:24:31,400 --> 00:24:32,880
ABOUT THE CANCER FELLOWSHIP

562
00:24:32,880 --> 00:24:34,680
PROGRAM AND EVEN THOUGH I WAS AT

563
00:24:34,680 --> 00:24:35,960
HOPKINS, IT NEVER OCCURRED THAT

564
00:24:35,960 --> 00:24:37,600
PEOPLE DO THAT KIND OF WORK.

565
00:24:37,600 --> 00:24:41,760
AND I WAS NOT A KID AT THAT

566
00:24:41,760 --> 00:24:44,840
POINT.

567
00:24:44,840 --> 00:24:49,000
I WOULD HAVE BENEFITED EARLIER

568
00:24:49,000 --> 00:24:49,680
OF.

569
00:24:49,680 --> 00:24:52,760
WE CAN'T START TOO YOUNG AND WE

570
00:24:52,760 --> 00:24:54,640
CAN'T START TOO YOUNG TO ADD

571
00:24:54,640 --> 00:24:58,480
DICE VERSE TEE INTO THIS AND WE

572
00:24:58,480 --> 00:25:00,480
NEED TO THINK EARLIER AND

573
00:25:00,480 --> 00:25:01,440
BROADER AND I DON'T CLAIM TO

574
00:25:01,440 --> 00:25:03,160
KNOW HOW TO DO THAT AND THAT IS

575
00:25:03,160 --> 00:25:04,240
WHY YOU ARE ON THIS BECAUSE YOU

576
00:25:04,240 --> 00:25:08,760
ARE THE SMART ONES BUT WE NEED

577
00:25:08,760 --> 00:25:11,600
TO GET AFTER THIS EARLY.

578
00:25:11,600 --> 00:25:12,920
>>CAN I ASK ONE OTHER
QUESTION.

579
00:25:12,920 --> 00:25:17,360
ARE YOU ALSO GOING TO

580
00:25:17,360 --> 00:25:20,600
SUPPLEMENTS SUPPLEMENT

581
00:25:20,600 --> 00:25:23,800
OPPORTUNITIES, MINORITY

582
00:25:23,800 --> 00:25:28,240
SUPPLEMENTS AND ON GRANTS AND

583
00:25:28,240 --> 00:25:29,760
YOUR ANALYSIS.

584
00:25:29,760 --> 00:25:31,680
>>WE'LL ADD THAT ON TO
THE

585
00:25:31,680 --> 00:25:31,920
LIST.

586
00:25:31,920 --> 00:25:37,160
>>THANK YOU.

587
00:25:37,160 --> 00:25:38,600
>>YOU JUST HIRED ONE OF
YOUR

588
00:25:38,600 --> 00:25:42,320
PREVENTION FELLOWS AND SHE'S

589
00:25:42,320 --> 00:25:42,880
FABULOUS.

590
00:25:42,880 --> 00:25:45,520
SO YOU ALL DO A GREAT JOB AND

591
00:25:45,520 --> 00:25:48,640
CROSS EPI PERSON AND YOU ARE

592
00:25:48,640 --> 00:25:50,600
RIGHT, IT REALLY MAKES A

593
00:25:50,600 --> 00:25:52,360
DIFFERENCE AND WORKING WITH MORE

594
00:25:52,360 --> 00:25:56,200
ABOUT THE CANCER CONTROL

595
00:25:56,200 --> 00:25:57,800
RESEARCHER IT'S JUST FABULOUS.

596
00:25:57,800 --> 00:25:58,600
>>GO AHEAD.

597
00:25:58,600 --> 00:26:00,720
>>I WOULD LOVE TO EXPAND
THE

598
00:26:00,720 --> 00:26:02,240
CAP SER PREVENTION FELLOWSHIP

599
00:26:02,240 --> 00:26:04,440
PROGRAM WHICH I CAME OUT OF.

600
00:26:04,440 --> 00:26:09,040
WE NEED TO REPLICATE IT INTO THE

601
00:26:09,040 --> 00:26:11,480
EXTRAMURAL COMMUNITY AS WELL AND

602
00:26:11,480 --> 00:26:15,760
I'M LOOKING FOR IDEAS ON HOW TO

603
00:26:15,760 --> 00:26:17,240
DO THAT FOR SURE.

604
00:26:17,240 --> 00:26:19,360
WE HAVE A WORKFORCE ISSUE IN THE

605
00:26:19,360 --> 00:26:21,000
CANCER PREVENTION SPACE AND WE

606
00:26:21,000 --> 00:26:24,360
NEED IF WE'RE GOING TO MAKE

607
00:26:24,360 --> 00:26:25,560
PROGRESS WE HAVE TO -- I NEED

608
00:26:25,560 --> 00:26:29,720
YOUR HELP, ABSOLUTELY, PLEASE.

609
00:26:29,720 --> 00:26:40,080
>>ARE YOU ON MUTE.

610
00:26:40,480 --> 00:26:41,280
>>HELLO.

611
00:26:41,280 --> 00:26:42,640
CAN YOU SEE ME NOW?

612
00:26:42,640 --> 00:26:44,880
>>I CAN HEAR YOU BUT I
CAN'T

613
00:26:44,880 --> 00:26:46,520
SEE YOU.

614
00:26:46,520 --> 00:26:50,480
>>IT DOES THAT.

615
00:26:50,480 --> 00:26:52,960
LET ME JUST TAKE MY VIDEO OFF

616
00:26:52,960 --> 00:26:56,880
AND TO NOT DISTRACT YOU AND I'VE

617
00:26:56,880 --> 00:26:59,960
BEEN HAVING THIS PROBLEM YOU CAN

618
00:26:59,960 --> 00:27:00,880
HEAR ME ALL RIGHT.

619
00:27:00,880 --> 00:27:04,400
>>THINKING ABOUT
EXTRAMURAL

620
00:27:04,400 --> 00:27:06,600
ENGAGEMENT AND THE MISSION TO

621
00:27:06,600 --> 00:27:12,080
ADVANCE SURVEILLANCE AND

622
00:27:12,080 --> 00:27:14,360
EPIDEMIOLOGY AND GENERAL AND I'M

623
00:27:14,360 --> 00:27:15,960
WONDERING ABOUT THE INTEREST

624
00:27:15,960 --> 00:27:17,840
THIS GROUP MIGHT HAVE IN

625
00:27:17,840 --> 00:27:19,520
ADVANCING MORE INTERSECTION WITH

626
00:27:19,520 --> 00:27:24,760
REGULATORY SCIENCES AND I THINK

627
00:27:24,760 --> 00:27:31,000
IN MY VIEW, THERE'S A LOT OF

628
00:27:31,000 --> 00:27:33,440
ADVANCES AND INTERESTS FROM THE

629
00:27:33,440 --> 00:27:34,600
REGULATORY SCIENCE PART IN

630
00:27:34,600 --> 00:27:38,120
FURTHER ENGAGEMENT WITH

631
00:27:38,120 --> 00:27:41,640
OFF-THE-RECORD STAKEHOLDERS AND

632
00:27:41,640 --> 00:27:51,480
THESTAKEHOLDERS AND CONDUCT OF E

633
00:27:51,480 --> 00:27:52,080
EXTERNALLY CONTROLLED TRIALS FOR

634
00:27:52,080 --> 00:27:53,720
DRUG AND BIOLOGICAL PRODUCTS.

635
00:27:53,720 --> 00:27:59,440
IT'S NOT JUST ABOUT TRIALS AND

636
00:27:59,440 --> 00:28:01,160
IT CAME OUT ON THE FDA WEBSITE

637
00:28:01,160 --> 00:28:02,760
IN FEBRUARY OF 2023.

638
00:28:02,760 --> 00:28:04,880
IT INCLUDES MULTIPLE CITATIONS

639
00:28:04,880 --> 00:28:08,880
AND REFERENCES TO A SERIES OF

640
00:28:08,880 --> 00:28:14,240
RECENT GUIDANCES ABOUT THE

641
00:28:14,240 --> 00:28:18,240
APPLICATIONS OF EPIDEMIOLOGY

642
00:28:18,240 --> 00:28:20,520
QUANTITIVE ANALYTIC APPROACHES

643
00:28:20,520 --> 00:28:23,480
THAT THE AGENCY THINKS ARE

644
00:28:23,480 --> 00:28:25,160
IMPORTANT FOR STAKEHOLDERS.

645
00:28:25,160 --> 00:28:26,680
NOW, I'M BIASES, YOU KNOW,

646
00:28:26,680 --> 00:28:31,840
BECAUSE I COME FROM INDUSTRY AND

647
00:28:31,840 --> 00:28:37,280
IT HAS TO BETTER ALIGN AND

648
00:28:37,280 --> 00:28:38,360
INTERSECT AND UNDERSTAND THESE

649
00:28:38,360 --> 00:28:39,800
THINGS BECAUSE THEY'RE PART OF

650
00:28:39,800 --> 00:28:42,280
POST-DRUG APPROVAL REQUIREMENTS.

651
00:28:42,280 --> 00:28:44,680
WE'RE GETTING APPROVALS BASED ON

652
00:28:44,680 --> 00:28:46,640
SMALLER INDICATIONS BUT THEN

653
00:28:46,640 --> 00:28:51,080
THERE'S A POST APPROVAL

654
00:28:51,080 --> 00:28:53,320
REQUIREMENT TO DO A BROAD

655
00:28:53,320 --> 00:28:56,640
REGISTRY OR EPIDEMIOLOGY

656
00:28:56,640 --> 00:28:57,840
ANALYSIS TO UNDERSTAND EFFECTS

657
00:28:57,840 --> 00:28:59,760
IN SUB POPULATIONS AND WHETHER

658
00:28:59,760 --> 00:29:02,320
THE CONTROLS EFFECTS OF PEOPLE

659
00:29:02,320 --> 00:29:03,560
UNTREATED WITH DRUGS IN THOSE

660
00:29:03,560 --> 00:29:05,440
SUB POPULATIONS AND UNDERSTAND

661
00:29:05,440 --> 00:29:06,880
SERVED POPULATIONS AND SO I

662
00:29:06,880 --> 00:29:10,080
THINK IT'S AN INDUSTRY INTEREST

663
00:29:10,080 --> 00:29:12,360
AND I CAN THINK MAYBE IT MIGHT

664
00:29:12,360 --> 00:29:17,560
BE SOMETHING THAT WOULD DONE BY

665
00:29:17,560 --> 00:29:23,440
INVITING THE AGENTORS OF THE AUA

666
00:29:23,440 --> 00:29:25,840
GUIDANCE TO GIVE A PRESENTATION

667
00:29:25,840 --> 00:29:30,120
AND START A DIALOGUE WITH US

668
00:29:30,120 --> 00:29:35,880
HERE ABOUT ISSUES THEY VIEW AS

669
00:29:35,880 --> 00:29:38,000
IMPORTANT IN THIS FIELD.

670
00:29:38,000 --> 00:29:44,080
>>THANK YOU.

671
00:29:44,080 --> 00:29:45,960
IT'S OUT OF THE BOX BUT I REALLY

672
00:29:45,960 --> 00:29:46,880
LIKE IT.

673
00:29:46,880 --> 00:29:47,320
IT'S INTERESTING.

674
00:29:47,320 --> 00:29:49,440
THANK YOU, HOWARD.

675
00:29:49,440 --> 00:29:52,240
>>WELL, I MEAN, SIGH --
JUST

676
00:29:52,240 --> 00:29:53,000
ONE LAST THING.

677
00:29:53,000 --> 00:29:56,040
I SEE THIS ALSO IN TERMS OF

678
00:29:56,040 --> 00:29:57,600
IMPLICATIONS FOR LARGER GRANTS.

679
00:29:57,600 --> 00:30:01,360
YOU KNOW, WE'RE GETTING MORE OF

680
00:30:01,360 --> 00:30:02,120
THESE LARGER GRANTS BECAUSE

681
00:30:02,120 --> 00:30:04,760
THEY'RE INVOLVING LARGE CLINICAL

682
00:30:04,760 --> 00:30:06,520
TRIALS OR YOU KNOW TRANSLATIONAL

683
00:30:06,520 --> 00:30:08,880
INTO THE CLINIC AND IT COSTS

684
00:30:08,880 --> 00:30:09,880
MORE MONEY.

685
00:30:09,880 --> 00:30:12,600
BUT SOMETIMES THE ANALYTIC

686
00:30:12,600 --> 00:30:14,000
APPROACHES BEING TAKEN, YOU

687
00:30:14,000 --> 00:30:16,160
KNOW, I CAN CITE GOG TRIALS THAT

688
00:30:16,160 --> 00:30:19,280
HAVE BEEN DONE, SURVEILLANCE --

689
00:30:19,280 --> 00:30:22,600
THEY WERE SURVEILLANCE STUDIES

690
00:30:22,600 --> 00:30:24,880
AND CLTB TRIALS I WORKED ON OVER

691
00:30:24,880 --> 00:30:25,480
THE YEARS.

692
00:30:25,480 --> 00:30:26,760
THERE WERE ESSENTIALLY

693
00:30:26,760 --> 00:30:28,160
SURVEILLANCE KIND OF LATE ON

694
00:30:28,160 --> 00:30:32,760
SETS SAFETY STUDIES AND I THINK

695
00:30:32,760 --> 00:30:34,840
THOSE ARE OUTDATED NOW AND

696
00:30:34,840 --> 00:30:36,280
REALLY DID NOT ANSWER SOME OF

697
00:30:36,280 --> 00:30:38,160
THE QUESTIONS THAT THEY WERE

698
00:30:38,160 --> 00:30:40,720
FUNDED TO ANSWER SO I WOULD HOPE

699
00:30:40,720 --> 00:30:41,760
MORE THAN WE WOULD LEARN BETTER

700
00:30:41,760 --> 00:30:45,320
FROM THE REGULATORS ON HOW TO

701
00:30:45,320 --> 00:30:47,160
DESIGN THOSE KINDS OF TRIALS

702
00:30:47,160 --> 00:30:48,960
BETTER TO ADDRESS WHAT IS GOING

703
00:30:48,960 --> 00:30:51,040
ON AND UNDERSERVED POPULATIONS,

704
00:30:51,040 --> 00:30:52,440
HOW TO INCORPORATE THINGS LIKE

705
00:30:52,440 --> 00:31:00,520
YOU MAY HAVE HEARD WHAT'S CALLEY

706
00:31:00,520 --> 00:31:06,000
OF DIAGNOSTIC PROBLEMS THAT

707
00:31:06,000 --> 00:31:07,880
HAPPEN WHEN YOU HAVE EXTERNAL

708
00:31:07,880 --> 00:31:10,440
DIAGNOSIS THAT HAVE A DIFFERENT

709
00:31:10,440 --> 00:31:12,080
DENSITY IT'S CALLED DIAGNOSTIC

710
00:31:12,080 --> 00:31:14,040
DENSITY AND IT'S IN THE

711
00:31:14,040 --> 00:31:14,520
EPIDEMIOLOGY FIELD.

712
00:31:14,520 --> 00:31:16,760
WHERE THE DIAGNOSIS IS REALLY

713
00:31:16,760 --> 00:31:19,120
INFLUENCED BY LIKE THE FREQUENCY

714
00:31:19,120 --> 00:31:21,560
OF HOW MUCH THINGS ARE MEASURED

715
00:31:21,560 --> 00:31:22,920
IN DIFFERENT POPULATION AND

716
00:31:22,920 --> 00:31:24,360
DIFFERENT REGIONS.

717
00:31:24,360 --> 00:31:26,960
SO NOW THERE'S REGIONAL AN LIT

718
00:31:26,960 --> 00:31:30,600
TICKS THAT HAVE BEEN DONE TO

719
00:31:30,600 --> 00:31:35,440
SHOW THAT ZIP CODES WHERE

720
00:31:35,440 --> 00:31:36,240
DIAGNOSTICS ARE DONE AND YOU

721
00:31:36,240 --> 00:31:37,960
FIND EVENTS IN THAT POPULATION.

722
00:31:37,960 --> 00:31:42,280
IT'S JUST ONE EXAMPLE OF WHAT

723
00:31:42,280 --> 00:31:42,880
I'M THINKING OF HERE.

724
00:31:42,880 --> 00:31:44,080
>>WOW, INTERESTING.

725
00:31:44,080 --> 00:31:47,480
THANK YOU.

726
00:31:47,480 --> 00:31:48,840
THANK YOU.

727
00:31:48,840 --> 00:31:50,960
WE USED TO LOOK AT THAT IN EPI

728
00:31:50,960 --> 00:31:53,440
FROM A INDIVIDUAL BASIS, NOT

729
00:31:53,440 --> 00:31:57,680
FROM A COMMUNITY BASIS OR ZIP

730
00:31:57,680 --> 00:31:59,360
CODE LEVEL SO THERE'S A BUY AS

731
00:31:59,360 --> 00:32:01,200
OUT THERE BUT IT'S INTERESTING

732
00:32:01,200 --> 00:32:02,720
BEING APPLIED TO A WHOLE

733
00:32:02,720 --> 00:32:09,560
POPULATION AND COMMUNITIES.

734
00:32:09,560 --> 00:32:16,360
THANK YOU, HOWARD.

735
00:32:16,360 --> 00:32:17,480
ANN --

736
00:32:17,480 --> 00:32:18,480
>>THERE WE GO.

737
00:32:18,480 --> 00:32:21,720
>>I THOUGHT WE WERE
UNMUTED

738
00:32:21,720 --> 00:32:22,920
AUTOMATICALLY.

739
00:32:22,920 --> 00:32:25,800
SO, I'M COMMENTING ON A POINT

740
00:32:25,800 --> 00:32:28,080
THAT I THINK PHIL MADE EX I

741
00:32:28,080 --> 00:32:29,360
THINK ABOUT IT A LOT AND THAT

742
00:32:29,360 --> 00:32:34,840
IS, YOU KNOW, BACK IN THE EARLY

743
00:32:34,840 --> 00:32:38,200
2000s, WE DID AN ENORMOUS

744
00:32:38,200 --> 00:32:40,800
AMOUNT OF GERM ONE SEQUENCES

745
00:32:40,800 --> 00:32:43,400
THROUGH COHORTS, AS YOU ALL

746
00:32:43,400 --> 00:32:44,240
RECALL, AROUND EVERY CANCER.

747
00:32:44,240 --> 00:32:46,760
AND IN SOME WAYS WE'VE KIND OF

748
00:32:46,760 --> 00:32:48,200
MOVED ON FROM THAT BUT A LOT HAS

749
00:32:48,200 --> 00:32:49,120
HAPPENED SINCE THEN.

750
00:32:49,120 --> 00:32:52,800
IN TERMS OF CHANGES IN GENOMICS

751
00:32:52,800 --> 00:32:55,280
AND TECHNOLOGY, ESPECIALLY

752
00:32:55,280 --> 00:32:57,520
AROUND NOT JUST THE COVERAGE,

753
00:32:57,520 --> 00:32:59,960
THE LEVEL OF COVERAGE IN THE

754
00:32:59,960 --> 00:33:01,760
GENOME BUT THE DEPTH OF COVERAGE

755
00:33:01,760 --> 00:33:05,360
AND ALSO THE ABILITY TO IDENTIFY

756
00:33:05,360 --> 00:33:06,320
ADDITIONAL GERM LINE MUTATIONS

757
00:33:06,320 --> 00:33:08,720
AND CHANGES THAT YOU KNOW, MAYBE

758
00:33:08,720 --> 00:33:09,840
THERE'S STILL CONSIDERED SMALL

759
00:33:09,840 --> 00:33:11,800
CHANGES BUT IN POPULATIONS, THEY

760
00:33:11,800 --> 00:33:17,840
HAVE A BIG IMPACT.

761
00:33:17,840 --> 00:33:19,040
WE'RE MOVING INTO A BETTER VIEW

762
00:33:19,040 --> 00:33:22,080
OF THE WHOLE GENOME BY DOING

763
00:33:22,080 --> 00:33:23,400
SEQUENCES ON THE GENOME AND IT'S

764
00:33:23,400 --> 00:33:25,320
GOING TO TURN UP EVEN MORE

765
00:33:25,320 --> 00:33:27,040
INTERESTING, I THINK,

766
00:33:27,040 --> 00:33:28,520
OPPORTUNITIES FOR US TO

767
00:33:28,520 --> 00:33:32,720
UNDERSTAND WHAT IS IN THE GERM

768
00:33:32,720 --> 00:33:32,920
LINE.

769
00:33:32,920 --> 00:33:35,760
THIS WEEK ALONE, WE LEARNED WE

770
00:33:35,760 --> 00:33:37,640
NOW HAVE PRETTY GOOD EVIDENCE

771
00:33:37,640 --> 00:33:39,520
THAT THEY'RE GOING TO BE TRAITS

772
00:33:39,520 --> 00:33:41,640
INHERITED AT LEAST FOR THREE

773
00:33:41,640 --> 00:33:43,880
GENERATIONS.

774
00:33:43,880 --> 00:33:45,400
DUE TO CHANGES IN METHYLATION

775
00:33:45,400 --> 00:33:46,600
WHICH NO ONE WOULD HAVE GUESSED.

776
00:33:46,600 --> 00:33:48,280
WHEN WE THINK WE KNOW SOMETHING

777
00:33:48,280 --> 00:33:50,760
AND CANCER BIOLOGY WE FIND OUT

778
00:33:50,760 --> 00:33:55,840
WE DON'T KNOW ENOUGH AND SO I

779
00:33:55,840 --> 00:33:58,520
THINK THAT WE'RE LOOKING AT

780
00:33:58,520 --> 00:34:00,640
OPPORTUNITIES THAT WE NEED TO

781
00:34:00,640 --> 00:34:03,080
TIE INTO SCALE KNOWING HOW THESE

782
00:34:03,080 --> 00:34:05,120
THINGS IMPACT AND I THOUGHT THE

783
00:34:05,120 --> 00:34:06,400
REPORT THAT THIS COMMITTEE DID,

784
00:34:06,400 --> 00:34:09,240
THIS SUBCOMMITTEE DID ON THE

785
00:34:09,240 --> 00:34:10,560
CONSORTIA OPPORTUNITIES ARE

786
00:34:10,560 --> 00:34:12,360
ENORMOUS HERE BUT I THINK THAT

787
00:34:12,360 --> 00:34:19,320
WE NEED O START P TO START PAYIO

788
00:34:19,320 --> 00:34:21,360
THIS AND WE SHOULDN'T MOVE

789
00:34:21,360 --> 00:34:22,200
BEYOND GERM LINE THERE'S A LOT

790
00:34:22,200 --> 00:34:23,560
TO KNOW HERE AND THERE'S A LOT

791
00:34:23,560 --> 00:34:25,160
THAT NEEDS TO BE SOLVED AND IT'S

792
00:34:25,160 --> 00:34:26,800
GOING TO IMPACT EVERYTHING WE DO

793
00:34:26,800 --> 00:34:28,960
BECAUSE SO MUCH OF WHAT WE'RE

794
00:34:28,960 --> 00:34:31,320
TALKING ABOUT IN TERMS OF

795
00:34:31,320 --> 00:34:33,720
MINORITY POPULATIONS, I BELIEVE

796
00:34:33,720 --> 00:34:36,960
INCREASINGLY MIGHT VERY WELL

797
00:34:36,960 --> 00:34:39,520
FIND SOME NOM IN TERMS OF

798
00:34:39,520 --> 00:34:40,120
INCREASING KNOWLEDGE IN THE

799
00:34:40,120 --> 00:34:42,320
CHANGES IN THE GENOME THAT ARE

800
00:34:42,320 --> 00:34:46,240
MAYBE MORE SUBTLE THAN WE

801
00:34:46,240 --> 00:34:48,200
THOUGHT ABOUT.

802
00:34:48,200 --> 00:34:49,800
WE NEED DEDICATION TO THIS

803
00:34:49,800 --> 00:34:51,520
BECAUSE WE NEED TO (INAUDIBLE)

804
00:34:51,520 --> 00:34:54,120
THIS BIOLOGY AND I'M NOT WISE

805
00:34:54,120 --> 00:34:56,560
ENOUGH AT THIS MOMENT TO KNOW IF

806
00:34:56,560 --> 00:35:00,440
IT'S A SUPER CO CONSORTIA OR HOE

807
00:35:00,440 --> 00:35:02,400
GET THE POWER TO FIND OUT HOW

808
00:35:02,400 --> 00:35:03,880
IMPORTANT ARE SOME OF THESE

809
00:35:03,880 --> 00:35:07,880
FINDINGS, ESPECIALLY IN THE EPI

810
00:35:07,880 --> 00:35:11,320
GENOMICS IS GOING TO BE

811
00:35:11,320 --> 00:35:12,240
IMPORTANT.

812
00:35:12,240 --> 00:35:13,280
>>THANK YOU, IT THANK
YOU, VERY

813
00:35:13,280 --> 00:35:13,840
MUCH.

814
00:35:13,840 --> 00:35:14,640
ANYBODY HAVE ANY COMMENTS ON

815
00:35:14,640 --> 00:35:25,000
EITHER OF THOSE IDEAS?

816
00:35:25,400 --> 00:35:28,040
ANYBODY HAVE ANY NEW IDEAS?

817
00:35:28,040 --> 00:35:29,200
ANY OTHER IDEAS?

818
00:35:29,200 --> 00:35:29,560
MARGARET?

819
00:35:29,560 --> 00:35:32,680
>>I THINK WHAT ANNA SAID
IS

820
00:35:32,680 --> 00:35:33,400
VERY VALUABLE.

821
00:35:33,400 --> 00:35:37,520
I THINK TO SOME EXTENT, THE

822
00:35:37,520 --> 00:35:38,600
RESEARCHERS HAVE STARTED

823
00:35:38,600 --> 00:35:40,560
THINKING ABOUT THE IMPORTANCE OF

824
00:35:40,560 --> 00:35:42,600
THIS AND YOU KNOW, TO SOME SMALL

825
00:35:42,600 --> 00:35:44,120
DEGREE THEY'RE DOING IT ALREADY

826
00:35:44,120 --> 00:35:47,440
BUT CLEARLY IT HAS TO BE DI DONN

827
00:35:47,440 --> 00:35:48,280
A LARGE-SCALE.

828
00:35:48,280 --> 00:35:50,360
I LOOKED BACK IN MY NOTES AND I

829
00:35:50,360 --> 00:35:52,360
THINK IT WAS DOUG LOWE ALTHOUGH

830
00:35:52,360 --> 00:35:56,840
IT MIGHT HAVE BEEN Dr.

831
00:35:56,840 --> 00:35:58,320
SHARPLESS, AND THEY ASKED US,

832
00:35:58,320 --> 00:36:00,640
BESIDES WHAT WE'VE ALREADY DONE,

833
00:36:00,640 --> 00:36:04,200
TO REVIEW HOW TO LEVERAGE

834
00:36:04,200 --> 00:36:09,080
MINORITY ENROLLMENT IN TRIALS

835
00:36:09,080 --> 00:36:10,600
AND SPECIFICALLY IN COMMUNITY

836
00:36:10,600 --> 00:36:12,840
TRIALS AND I THINK THAT THAT'S A

837
00:36:12,840 --> 00:36:15,760
MASSIVE TOPIC TO ADDRESS BUT IT

838
00:36:15,760 --> 00:36:16,720
WAS MENTIONED AS PERHAPS

839
00:36:16,720 --> 00:36:19,360
SOMETHING WE NEEDED TO BEGIN TO

840
00:36:19,360 --> 00:36:22,360
LOOK AT.

841
00:36:22,360 --> 00:36:23,560
I SEE ELECTRA YOU ARE NODDING.

842
00:36:23,560 --> 00:36:26,120
>>YES, IT'S ON MY LIST.

843
00:36:26,120 --> 00:36:27,880
RIGHT UNDER THE FUNDING FOR

844
00:36:27,880 --> 00:36:30,000
TRAINEES AND POPULATION SCIENCE,

845
00:36:30,000 --> 00:36:32,160
WHICH YOU HAVE MENTIONED BEFORE.

846
00:36:32,160 --> 00:36:39,880
SECOND WAS CLINICAL TRIAL

847
00:36:39,880 --> 00:36:42,000
ACCRUAL, UNDERSERVED MINORITY

848
00:36:42,000 --> 00:36:44,480
AND ACROSS THE AGE RANGE NOW IS

849
00:36:44,480 --> 00:36:46,720
OUR AND RURAL URBAN POPULATIONS,

850
00:36:46,720 --> 00:36:51,400
ET CETERA.

851
00:36:51,400 --> 00:36:53,320
AND POPULATION SCIENCE AND

852
00:36:53,320 --> 00:36:55,240
IMMUNO ONCOLOGY WAS ON THE LIST

853
00:36:55,240 --> 00:36:56,600
AND THEN BIDIRECTIONAL

854
00:36:56,600 --> 00:36:58,600
COMMUNICATION BETWEEN

855
00:36:58,600 --> 00:36:59,760
RESEARCHERS AND COMMUNITY.

856
00:36:59,760 --> 00:37:02,640
THAT WAS ON MY LIST.

857
00:37:02,640 --> 00:37:06,360
SO WE'VE MENTIONED TWO.

858
00:37:06,360 --> 00:37:07,440
GOOD TO SEE YOU, DOUG.

859
00:37:07,440 --> 00:37:12,920
>>HI ELECTRA, I JUST
WANTED TO

860
00:37:12,920 --> 00:37:13,440
RESPOND TO YOUR COMMENTS.

861
00:37:13,440 --> 00:37:17,280
WHEN IT IT COMES TO MINORITY

862
00:37:17,280 --> 00:37:21,040
ENROLLMENT IN NCI SPONSORED

863
00:37:21,040 --> 00:37:23,480
TRIALS, THIS WAS THE

864
00:37:23,480 --> 00:37:25,680
CO-OPERATIVE GROUPS AND ENCORE

865
00:37:25,680 --> 00:37:26,640
TRIALS AS I HAVE MENTIONED IN

866
00:37:26,640 --> 00:37:30,600
THE PAST, OVER THE LAST 20

867
00:37:30,600 --> 00:37:34,440
YEARS, WE HAVE GONE FROM 14%

868
00:37:34,440 --> 00:37:37,600
MINORITY ENROLLMENT TO ABOUT

869
00:37:37,600 --> 00:37:38,200
25%.

870
00:37:38,200 --> 00:37:42,640
THOSE DATA ARE THROUGH 2019 AND

871
00:37:42,640 --> 00:37:45,440
THE LAST TWO YEARS, 20 AND '21,

872
00:37:45,440 --> 00:37:49,720
THE PREPORTION OF UNDER

873
00:37:49,720 --> 00:37:53,440
REPRESENTED MINORITIES WAS EVEN

874
00:37:53,440 --> 00:37:54,640
HIGHER.

875
00:37:54,640 --> 00:37:57,640
AND I THINK THAT YOU KNOW, THIS

876
00:37:57,640 --> 00:38:00,200
WAS PRESENTED IN A WHILE AGO AND

877
00:38:00,200 --> 00:38:03,880
COULD BE PRESENTED AGAIN IF YOU

878
00:38:03,880 --> 00:38:04,720
WERE INTERESTED.

879
00:38:04,720 --> 00:38:09,080
AND THEN IN TERMS OF WOMEN WITH

880
00:38:09,080 --> 00:38:12,200
THE NOTABLE EXCEPTION OF QUITE A

881
00:38:12,200 --> 00:38:15,840
FEW YEARS AGO WHEN WE WERE

882
00:38:15,840 --> 00:38:20,520
ENROLLING FOR PROSTATE CANCER,

883
00:38:20,520 --> 00:38:23,360
WOMEN ACCOUNT FOR 60% OF THE

884
00:38:23,360 --> 00:38:27,080
PATIENTS WHO ARE ENROLLED IN NCI

885
00:38:27,080 --> 00:38:30,960
SPONSORED CLINICAL TRIALS.

886
00:38:30,960 --> 00:38:33,920
>>THANK YOU, DOUG.

887
00:38:33,920 --> 00:38:37,160
I DO WANT TO SAY JUST A COUPLE

888
00:38:37,160 --> 00:38:39,160
OF THINGS BEFORE WE GET TO KAREN

889
00:38:39,160 --> 00:38:41,640
AND JOHN AND THE GAINS THAT WE

890
00:38:41,640 --> 00:38:45,040
SEE AND WE'RE REPORTED BY WARDA

891
00:38:45,040 --> 00:38:49,760
ARE NOT UNIVERSAL ACROSS CAP SER

892
00:38:49,760 --> 00:38:51,040
CENTERS.

893
00:38:51,040 --> 00:38:54,760
AND I CAN SAY THAT WITH GREAT

894
00:38:54,760 --> 00:38:57,080
ASSURITY BECAUSE I VISIT A LOT

895
00:38:57,080 --> 00:39:01,560
OF PLACES AND WE DO ALSO NEED TO

896
00:39:01,560 --> 00:39:08,760
DO FURTHER WORK IN THAT AREA IN

897
00:39:08,760 --> 00:39:10,560
TERMS OF OUR RURAL POPULATIONS

898
00:39:10,560 --> 00:39:14,600
AND ACROSS THE LIFESPAN AND I

899
00:39:14,600 --> 00:39:18,520
ALSO STRONGLY SUGGEST WE MENTION

900
00:39:18,520 --> 00:39:20,400
INSIDE OUR REPORT THAT WE

901
00:39:20,400 --> 00:39:30,960
DISAGGREGATE RACE AND ETHNICITY.

902
00:39:33,600 --> 00:39:35,120
SOMETHING JUST CAME OUT FOR NEW

903
00:39:35,120 --> 00:39:38,200
GUIDELINES FOR THE NIH FOR

904
00:39:38,200 --> 00:39:40,480
REPORTING A RACE ETHNICITY VERY

905
00:39:40,480 --> 00:39:43,760
SIMILAR TO THE 2020 CENSUS WHICH

906
00:39:43,760 --> 00:39:46,120
THERE SOME DISAGGREGATION BUT

907
00:39:46,120 --> 00:39:49,560
NOT QUITE TO THE DEGREE THAT WE

908
00:39:49,560 --> 00:39:50,600
SUGGESTED.

909
00:39:50,600 --> 00:39:52,360
SO, THERE'S STILL A LOT TO LOOK

910
00:39:52,360 --> 00:39:55,080
AT IN THIS AREA AND YOU KNOW I

911
00:39:55,080 --> 00:40:00,960
THINK THE INCORP IS IS A MODEL

912
00:40:00,960 --> 00:40:02,880
FOR SUCCESS THAT I WISH OTHER

913
00:40:02,880 --> 00:40:04,320
PEOPLE COULD REPLICATE BECAUSE

914
00:40:04,320 --> 00:40:06,600
IT'S NOT AND WE ALSO HAVE FDA

915
00:40:06,600 --> 00:40:10,200
TRIALS THAT WE KNOW ARE REALLY

916
00:40:10,200 --> 00:40:11,800
SUFFERING FROM THIS.

917
00:40:11,800 --> 00:40:13,200
KAREN, GO AHEAD, PLEASE.

918
00:40:13,200 --> 00:40:16,640
>>YES, HEAR HEAR.

919
00:40:16,640 --> 00:40:18,440
IT'S A MAJOR ISSUE PARTICULARLY

920
00:40:18,440 --> 00:40:20,320
WHEN WE WERE TALKING ABOUT DRUG

921
00:40:20,320 --> 00:40:22,360
DISCOVERY AND CANCER CARE SPACE

922
00:40:22,360 --> 00:40:23,880
AND DON'T HAVE ADEQUATE

923
00:40:23,880 --> 00:40:25,600
REPRESENTATION SO THANK YOU FOR

924
00:40:25,600 --> 00:40:26,040
THAT.

925
00:40:26,040 --> 00:40:32,600
I DO WANT TO -- IF I CAN GO BACK

926
00:40:32,600 --> 00:40:35,920
TO SOMETHING PHILLIP MENTIONED

927
00:40:35,920 --> 00:40:37,480
ABOUT THE TRANSLATIONAL SCIENCE

928
00:40:37,480 --> 00:40:39,360
AND HAVING THIS BIDIRECTIONAL

929
00:40:39,360 --> 00:40:40,920
COMMUNICATION BETWEEN POPULATION

930
00:40:40,920 --> 00:40:44,640
AND BETWEEN BASIC SCIENTISTS AND

931
00:40:44,640 --> 00:40:46,040
COMMUNITY AND THERE WAS A

932
00:40:46,040 --> 00:40:46,760
SUPPLEMENT THAT CAME OUT A

933
00:40:46,760 --> 00:40:49,360
COUPLE OF YEARS AGO THAT I GOT

934
00:40:49,360 --> 00:40:51,120
AND I LOOKED JUST THAT THE AND I

935
00:40:51,120 --> 00:40:52,080
DON'T KNOW IF ANYBODY LOOKED AT

936
00:40:52,080 --> 00:40:52,800
THAT DATA.

937
00:40:52,800 --> 00:40:54,440
HAVE WE LOOKED, ALL THESE

938
00:40:54,440 --> 00:40:55,640
SUPPLEMENTS COME OUT AND I JUST

939
00:40:55,640 --> 00:40:57,400
DON'T KNOW HOW THAT DATA IS

940
00:40:57,400 --> 00:41:01,080
BEING AGGREGATE AND LOOKED AT

941
00:41:01,080 --> 00:41:02,040
AND EVALUATED.

942
00:41:02,040 --> 00:41:06,320
WE TOOK TWO PROGRAMS AT OUR

943
00:41:06,320 --> 00:41:14,320
CANCER AND IT HELPS UNDERSTAND

944
00:41:14,320 --> 00:41:15,520
THE VALUE OF COMMUNITY

945
00:41:15,520 --> 00:41:16,840
ENGAGEMENT AND THE OTHER THING

946
00:41:16,840 --> 00:41:18,800
THAT IS IMPORTANT AND IN OF THE

947
00:41:18,800 --> 00:41:20,960
ROLES, SOME OF US WHO HAVE BEEN

948
00:41:20,960 --> 00:41:25,160
ADs, WHE WE WERE REALLY

949
00:41:25,160 --> 00:41:27,120
INTENTIONAL THINKING ABOUT BASIC

950
00:41:27,120 --> 00:41:27,760
SCIENTISTS AROUND THE PREVENTION

951
00:41:27,760 --> 00:41:28,520
SIDE THAT WAS ONE OF THE THINGS

952
00:41:28,520 --> 00:41:30,280
THAT CAME UP.

953
00:41:30,280 --> 00:41:31,640
BECAUSE, FRIENDSHIPS, MA LAB A

954
00:41:31,640 --> 00:41:32,400
LOAM I CAN IS MASSIVE.

955
00:41:32,400 --> 00:41:34,320
WE KNOW THAT OBESITY WILL BE THE

956
00:41:34,320 --> 00:41:36,640
NUMBER ONE MODIFIABLE RISK

957
00:41:36,640 --> 00:41:39,840
FACTOR FOR CANCER SO THERE MIGHT

958
00:41:39,840 --> 00:41:40,880
BE INDIVIDUALS WHO ARE DOING

959
00:41:40,880 --> 00:41:43,680
WORK IN ONE AREA THAT MAY NOT

960
00:41:43,680 --> 00:41:45,080
UNDERSTAND HOW IT TRANSLATES TO

961
00:41:45,080 --> 00:41:48,040
CANCER BUT THOSE OF US WHO ARE

962
00:41:48,040 --> 00:41:51,480
ADs OR ADFCOE HAVE HAD THAT ON

963
00:41:51,480 --> 00:41:53,000
OUR MINDS FOR A LONG TIME SO I

964
00:41:53,000 --> 00:41:53,920
DON'T KNOW WHAT DATA HAS BEEN

965
00:41:53,920 --> 00:41:55,600
PULLED TOGETHER AND COLLATED --

966
00:41:55,600 --> 00:41:57,400
I THINK FROM THE SUPPLEMENTS

967
00:41:57,400 --> 00:41:59,280
THAT WITH SHOULD HAVE THAT DATA

968
00:41:59,280 --> 00:42:02,640
BUT IT WOULD BE INTERESTING TO

969
00:42:02,640 --> 00:42:05,280
LOOK AT THAT.

970
00:42:05,280 --> 00:42:08,200
>>YES, I RECALL THOSE

971
00:42:08,200 --> 00:42:09,040
SUPPLEMENTS AND I DON'T REMEMBER

972
00:42:09,040 --> 00:42:10,920
HEARING SORT OF THE END PRODUCT.

973
00:42:10,920 --> 00:42:14,560
I'M SURE IT'S SOMEWHERE.

974
00:42:14,560 --> 00:42:15,800
THERE'S VERY GOOD EVALUATION OF

975
00:42:15,800 --> 00:42:16,520
THESE.

976
00:42:16,520 --> 00:42:22,160
THANK YOU, CARRE KAREN.

977
00:42:22,160 --> 00:42:22,840
>>THANK YOU.

978
00:42:22,840 --> 00:42:23,840
THAT WAS A GREAT CONVERSATION

979
00:42:23,840 --> 00:42:24,600
AND DISCUSSION.

980
00:42:24,600 --> 00:42:26,320
JUST A COUPLE OF THINGS, I AGREE

981
00:42:26,320 --> 00:42:30,160
WITH YOU, ELECTRA, ABOUT THE

982
00:42:30,160 --> 00:42:33,160
TRIAL AND ACCRUAL NUMBERS AND

983
00:42:33,160 --> 00:42:35,640
YOU KNOW IT'S NOT UNIVERSAL AND

984
00:42:35,640 --> 00:42:37,320
I THINK I REMEMBER IN OF THOSE

985
00:42:37,320 --> 00:42:40,400
NUMBERS BEING PRESENTED AND

986
00:42:40,400 --> 00:42:41,560
SPECIFICALLY ASKING THE QUESTION

987
00:42:41,560 --> 00:42:45,360
ARE THESE OF ALL TRIALS OR HAVE

988
00:42:45,360 --> 00:42:47,320
YOU STRATIFIED BY THERAPEUTIC

989
00:42:47,320 --> 00:42:48,480
VERSIONS ALL INTERVENTIONAL AND

990
00:42:48,480 --> 00:42:50,760
THE NUMBERS PLUMMET, RIGHT, WHEN

991
00:42:50,760 --> 00:42:55,320
YOU START TALK ABOUT PER

992
00:42:55,320 --> 00:42:58,360
THERAPEUTIC TRIALS AND I ASK WE

993
00:42:58,360 --> 00:43:01,360
SEE THE STRATIFICATION SO

994
00:43:01,360 --> 00:43:02,720
THAT -- YOU KNOW, IT'S OK TO

995
00:43:02,720 --> 00:43:04,920
KNOW THAT THERE'S A PROBLEM.

996
00:43:04,920 --> 00:43:05,320
RIGHT.

997
00:43:05,320 --> 00:43:07,280
IT DOESN'T HAVE TO ALWAYS BE

998
00:43:07,280 --> 00:43:08,400
PRESENTED TO SAY WE'RE MAKING

999
00:43:08,400 --> 00:43:09,000
PROGRESS.

1000
00:43:09,000 --> 00:43:10,360
IT'S OK TO SAY IT BECAUSE IT'S

1001
00:43:10,360 --> 00:43:12,160
THE ONLY WAY, RIGHT, WHERE WE'LL

1002
00:43:12,160 --> 00:43:13,960
KEEP IT IN FRONT OF US, THAT WAS

1003
00:43:13,960 --> 00:43:14,800
THE FIRST THING.

1004
00:43:14,800 --> 00:43:16,200
THE SECOND THING IS WE CONSIDER

1005
00:43:16,200 --> 00:43:19,040
THE WORKING GROUP AND I DON'T

1006
00:43:19,040 --> 00:43:21,040
KNOW IF I'M GET AGO HEAD OF

1007
00:43:21,040 --> 00:43:22,760
MYSELF BUT ALL OF THE WORKING

1008
00:43:22,760 --> 00:43:23,720
GROUPS, RIGHT.

1009
00:43:23,720 --> 00:43:26,080
THE TIMING IS GREAT, RIGHT.

1010
00:43:26,080 --> 00:43:29,320
WE CAN REALLY THINK ABOUT HOW

1011
00:43:29,320 --> 00:43:31,440
EVERYTHING ALLIANCE, RIGHT, IN

1012
00:43:31,440 --> 00:43:34,320
TERMS OF OUR NEW ILLUSTRIOUS

1013
00:43:34,320 --> 00:43:35,560
LEADER AND HER THOUGHTS AND

1014
00:43:35,560 --> 00:43:37,520
MAKING SURE THAT WE'RE ALIGNED,

1015
00:43:37,520 --> 00:43:40,120
RIGHT, WITH THE AGENDA AND WHERE

1016
00:43:40,120 --> 00:43:41,760
AWAY WANT TO SEE THINGS GO.

1017
00:43:41,760 --> 00:43:44,240
IT'S REALLY IMPORTANT TO TAKE A

1018
00:43:44,240 --> 00:43:46,240
LOT OF NOTES TODAY.

1019
00:43:46,240 --> 00:43:48,000
AND I HAVE A FEELING WE'RE GOING

1020
00:43:48,000 --> 00:43:49,840
TO REVISIT SOME OF THIS IN THE

1021
00:43:49,840 --> 00:43:51,840
NOT TOO DISTANT FUTURE TO REALLY

1022
00:43:51,840 --> 00:43:53,840
BEGIN TO THINK, HOW DO WE MAKE

1023
00:43:53,840 --> 00:43:55,920
SURE THAT EVERYTHING IS ALIGNED

1024
00:43:55,920 --> 00:43:57,720
AND THEN FINALLY, HOW EVERYTHING

1025
00:43:57,720 --> 00:43:59,720
IS INTEGRATED.

1026
00:43:59,720 --> 00:44:01,000
WE'RE GOING TO HAVE TO CONTINUE

1027
00:44:01,000 --> 00:44:03,480
TO GET OUT OF THIS SILOED

1028
00:44:03,480 --> 00:44:04,920
APPROACH TO THINGS.

1029
00:44:04,920 --> 00:44:06,760
IT'S POPULATION HERE AND IT'S

1030
00:44:06,760 --> 00:44:08,120
TRANSLATIONAL THERE AND IT'S

1031
00:44:08,120 --> 00:44:09,280
CLINICAL HERE AND IT'S BASIC

1032
00:44:09,280 --> 00:44:09,800
THERE.

1033
00:44:09,800 --> 00:44:11,560
WE'RE ONLY GOING TO GET OUT

1034
00:44:11,560 --> 00:44:15,280
THESE ISSUES, RIGHT, IF WE LOOK

1035
00:44:15,280 --> 00:44:18,200
ACROSS THE DISCIPLINES TOGETHER.

1036
00:44:18,200 --> 00:44:20,760
FINALLY, I KNOW IT'S APP ARDUOUS

1037
00:44:20,760 --> 00:44:23,040
TASK BUT WE TALK ABOUT

1038
00:44:23,040 --> 00:44:23,880
POPULATION, WE HAVE TO THINK

1039
00:44:23,880 --> 00:44:26,240
ABOUT ALL OF US, IT'S A HUGE

1040
00:44:26,240 --> 00:44:28,880
STUDY AND HOW DO WE BEGIN TO TAP

1041
00:44:28,880 --> 00:44:30,520
INTO THAT ON THE CANCER SIDE.

1042
00:44:30,520 --> 00:44:33,600
OF COURSE IT'S LONGITUDINAL SO

1043
00:44:33,600 --> 00:44:34,880
IT TAKES TIME BUT THE AMOUNT OF

1044
00:44:34,880 --> 00:44:36,560
DATA, THE AMOUNT OF INDIVIDUALS,

1045
00:44:36,560 --> 00:44:38,920
THE BIOSPECIMENS THAT ARE

1046
00:44:38,920 --> 00:44:41,000
AVAILABLE TO REALLY BEGIN TO

1047
00:44:41,000 --> 00:44:43,760
UNDERSTAND POPULATIONS SCIENCE,

1048
00:44:43,760 --> 00:44:46,160
I THINK WE HAVE TO FIGURE OUT,

1049
00:44:46,160 --> 00:44:48,480
MONICA, HOW DO WE IT TO TIE

1050
00:44:48,480 --> 00:44:54,920
DEEPER AND DEEPER INTO THAT

1051
00:44:54,920 --> 00:44:56,400
COHORT BECAUSE WE'LL GAIN A LOT

1052
00:44:56,400 --> 00:44:57,480
FROM THAT INFORMATION.

1053
00:44:57,480 --> 00:44:58,640
THOSE ARE MY COMMENTS.

1054
00:44:58,640 --> 00:44:59,840
>>SPLIT ON, JOHN.

1055
00:44:59,840 --> 00:45:00,200
THANK YOU.

1056
00:45:00,200 --> 00:45:02,440
>>I THINK YOU WILL BE OUR
LAST

1057
00:45:02,440 --> 00:45:05,600
NOT COMMENT BECAUSE WE HAVE SOME

1058
00:45:05,600 --> 00:45:09,120
SUMMARIZING TO DO AND CLOSING

1059
00:45:09,120 --> 00:45:10,160
OUT, PLEASE, GO AHEAD.

1060
00:45:10,160 --> 00:45:13,000
>>YEAH, JUST LISTENING TO
ALL

1061
00:45:13,000 --> 00:45:14,600
THIS, I'M STRUCK WITH, IF YOU

1062
00:45:14,600 --> 00:45:16,720
LOOK AT OUR RO1 POOL AND THE

1063
00:45:16,720 --> 00:45:18,080
SCIENCE THAT WE FUND AND SO MUCH

1064
00:45:18,080 --> 00:45:20,440
OF IT IS IS INCREASINGLY AND I

1065
00:45:20,440 --> 00:45:21,600
THINK VERY GOOD THING FOR US

1066
00:45:21,600 --> 00:45:23,560
BASIC SCIENCE, A LOT OF BASIC

1067
00:45:23,560 --> 00:45:24,000
SCIENCE.

1068
00:45:24,000 --> 00:45:25,720
AND A LOT OF TRANSLATIONAL

1069
00:45:25,720 --> 00:45:28,000
SCIENCE AND WHERE WE PLACE THE

1070
00:45:28,000 --> 00:45:29,640
FOCUS AND MANY DECADES FOR NOW

1071
00:45:29,640 --> 00:45:31,960
IS ON TRANSLATING THAT TO THE

1072
00:45:31,960 --> 00:45:32,640
CLINIC.

1073
00:45:32,640 --> 00:45:34,160
BUILDING BETTER CLINICAL TRIALS

1074
00:45:34,160 --> 00:45:38,680
FOR THE DOES OT DRUGS AND OTHER

1075
00:45:38,680 --> 00:45:39,480
INTERVENTIONS WE MAKE.

1076
00:45:39,480 --> 00:45:41,680
WHAT GETS MISSES IS WHAT WE'RE

1077
00:45:41,680 --> 00:45:42,880
DISCUSSING TODAY.

1078
00:45:42,880 --> 00:45:44,320
HOW YOU TIE ALL THIS THROUGH,

1079
00:45:44,320 --> 00:45:45,720
WHAT JOHN WAS TALKING ABOUT, IN

1080
00:45:45,720 --> 00:45:48,920
TERMS OF THIS INTEGRATIVE

1081
00:45:48,920 --> 00:45:50,280
APPROACH INTO POPULATION

1082
00:45:50,280 --> 00:45:50,920
SCIENCE.

1083
00:45:50,920 --> 00:45:53,160
IT'S THE LEAST EMPHASIZED AREA I

1084
00:45:53,160 --> 00:45:58,320
THINK OF CAR  KAREN BROUGHT THIS

1085
00:45:58,320 --> 00:45:59,760
UP AS WELL IN TERMS OF GRANTS.

1086
00:45:59,760 --> 00:46:02,000
WE HAVE TO CHANGE THAT.

1087
00:46:02,000 --> 00:46:03,840
IF THESE FINDING DON'T GET THE

1088
00:46:03,840 --> 00:46:07,680
POPULATION IN TERMS OF RISK AND

1089
00:46:07,680 --> 00:46:09,080
HOW WE DEAL WITH THAT, WE'RE NOT

1090
00:46:09,080 --> 00:46:09,600
GOING ANYWHERE.

1091
00:46:09,600 --> 00:46:14,960
WE CAN MAKE ALL THE DOES DO DRUE

1092
00:46:14,960 --> 00:46:16,920
KNOW THE RISK WE CAN'T DO IT IN

1093
00:46:16,920 --> 00:46:19,040
A SCIENTIFIC MATTER AND I THINK

1094
00:46:19,040 --> 00:46:20,320
WE HAVE PEOPLE OUT THERE NOW WHO

1095
00:46:20,320 --> 00:46:22,160
CAN BE TRAINED OR HAVE BEEN

1096
00:46:22,160 --> 00:46:23,360
TRAINED TOP DO THIS AND I THINK

1097
00:46:23,360 --> 00:46:26,040
WE HAD PLACE REAL EMPHASIS THERE

1098
00:46:26,040 --> 00:46:27,400
BECAUSE WE'RE LOSING A LOT OF

1099
00:46:27,400 --> 00:46:29,000
GROUND, I THINK, IN TERMS OF

1100
00:46:29,000 --> 00:46:30,600
TRANSLATING SOME OF THESE BASIC

1101
00:46:30,600 --> 00:46:36,240
FINDINGS TO POPULATIONS.

1102
00:46:36,240 --> 00:46:37,960
>>MANY OF US POPULATION

1103
00:46:37,960 --> 00:46:39,120
SCIENTISTS HAVE BEEN SAYING FOR

1104
00:46:39,120 --> 00:46:41,680
YEARS, YOU HAVE TO INTEGRATE US.

1105
00:46:41,680 --> 00:46:43,800
I SAY YOU CAN FIND A CURE FOR

1106
00:46:43,800 --> 00:46:45,880
CANCER BUT UNLESS YOU INVOLVE

1107
00:46:45,880 --> 00:46:48,480
THE POPULATION SCIENTISTS IT

1108
00:46:48,480 --> 00:46:49,920
WON'T BE DELIVERED TO THE

1109
00:46:49,920 --> 00:46:51,480
POPULATIONS WHO NEED IT

1110
00:46:51,480 --> 00:46:52,720
APPROPRIATELY AT THE RIGHT TIME

1111
00:46:52,720 --> 00:46:56,360
AND THE RIGHT WAY IN THE RIGHT

1112
00:46:56,360 --> 00:46:56,840
PLACE.

1113
00:46:56,840 --> 00:46:59,880
AND I THINK IT'S A GREAT POINT.

1114
00:46:59,880 --> 00:47:02,520
REALLY GREAT POINT.

1115
00:47:02,520 --> 00:47:06,040
WHEN WE TALKED ABOUT SOME GREAT

1116
00:47:06,040 --> 00:47:07,400
THINGS TODAY.

1117
00:47:07,400 --> 00:47:09,600
I WOULD LIKE PEOPLE TO START

1118
00:47:09,600 --> 00:47:11,840
THINKING ABOUT WHAT OUR MEETING

1119
00:47:11,840 --> 00:47:14,960
IN JUNE SHOULD LOOK LIKE.

1120
00:47:14,960 --> 00:47:16,680
YES, COVID IS IS A GREAT

1121
00:47:16,680 --> 00:47:19,480
EXAMPLE, YES, WE'VE GOT LOTS OF

1122
00:47:19,480 --> 00:47:20,680
EXAMPLES.

1123
00:47:20,680 --> 00:47:22,760
SO, WE CAN HAVE A MEETING IN

1124
00:47:22,760 --> 00:47:25,720
JUNE AND ANOTHER MEETING OF THIS

1125
00:47:25,720 --> 00:47:29,720
SUBCOMMITTEE IN JUNE.

1126
00:47:29,720 --> 00:47:31,320
I DON'T KNOW IF THE MEETINGS ARE

1127
00:47:31,320 --> 00:47:34,600
GOING TO BE FACE-TO-FACE IN JUNE

1128
00:47:34,600 --> 00:47:34,800
OR NOT.

1129
00:47:34,800 --> 00:47:37,280
WE CAN HAVE A MEETING.

1130
00:47:37,280 --> 00:47:40,120
AND WE COULD INVITE SEVERAL

1131
00:47:40,120 --> 00:47:42,720
PEOPLE TO COME AND GIVE US MORE

1132
00:47:42,720 --> 00:47:44,120
INFORMATION ABOUT THE TOPICS

1133
00:47:44,120 --> 00:47:48,080
THAT WE HAVE TALKED ABOUT.

1134
00:47:48,080 --> 00:47:49,680
SO, FOR EXAMPLE, PHIL HAS ASKED

1135
00:47:49,680 --> 00:47:52,200
FOR PERHAPS HIM AND KATRINA TO

1136
00:47:52,200 --> 00:47:55,680
COME TO PRESENT THEIR LANDSCAPE

1137
00:47:55,680 --> 00:48:00,920
ANALYSIS AND THAT WOULD REALLY

1138
00:48:00,920 --> 00:48:02,400
ADDRESS THE FIRST HALF OF PAGE

1139
00:48:02,400 --> 00:48:05,920
OF NOTES THAT I TOOK.

1140
00:48:05,920 --> 00:48:09,680
REGARDING SOME OF OUR QUESTIONS

1141
00:48:09,680 --> 00:48:11,800
THAT WE HAVE AND WE WOULD ALSO

1142
00:48:11,800 --> 00:48:13,680
LIKE PHIL, YOU SAID YOU WOULD

1143
00:48:13,680 --> 00:48:20,560
ADD SUPPLEMENTS AND TALK ABOUT

1144
00:48:20,560 --> 00:48:22,200
EXPANDING AND REPLICATING THE

1145
00:48:22,200 --> 00:48:25,280
CANCER PREVENTION FELLOWSHIP AND

1146
00:48:25,280 --> 00:48:28,680
THAT SO THAT IS IS -- THAT'S

1147
00:48:28,680 --> 00:48:30,680
WITHIN THING THAT WE COULD HAVE

1148
00:48:30,680 --> 00:48:37,000
AT OUR NEXT MEETING IS ONE

1149
00:48:37,000 --> 00:48:39,160
PRESENTATION ON THE ANALYSIS OF

1150
00:48:39,160 --> 00:48:41,760
TRAINING OPPORTUNITIES FOR

1151
00:48:41,760 --> 00:48:42,720
POPULATIONS SCIENCE.

1152
00:48:42,720 --> 00:48:46,680
WHAT DO PEOPLE THINK ABOUT THAT?

1153
00:48:46,680 --> 00:48:48,400
>>I LIKE THAT.

1154
00:48:48,400 --> 00:48:50,160
>>IT'S A GOOD PLACE TO
START

1155
00:48:50,160 --> 00:48:51,840
BECAUSE IT'S TIMELY AND THERE'S

1156
00:48:51,840 --> 00:48:56,520
ALREADY WORK GOING AND THEN I

1157
00:48:56,520 --> 00:48:57,560
THINK YOUR LIST ELECTRA, WE JUST

1158
00:48:57,560 --> 00:49:00,400
NEED TO MAKE SURE THERE'S

1159
00:49:00,400 --> 00:49:01,320
INSTITUTIONAL KNOWLEDGE TO KEEP

1160
00:49:01,320 --> 00:49:04,520
THAT LIST GOING SO WE CAN MOVE

1161
00:49:04,520 --> 00:49:06,280
FORWARD, YEAH.

1162
00:49:06,280 --> 00:49:08,680
>>I'M NOT DONE CHRIS.

1163
00:49:08,680 --> 00:49:09,760
JUST A SECOND.

1164
00:49:09,760 --> 00:49:11,520
LET'S DECIDE ON THIS TOPIC AND

1165
00:49:11,520 --> 00:49:12,360
THEN WE CAN MOVE ON.

1166
00:49:12,360 --> 00:49:14,960
I HAVE TO GO OUT OF TIME SO I

1167
00:49:14,960 --> 00:49:19,240
CAN KEEP ORGANIZED.

1168
00:49:19,240 --> 00:49:22,640
>>PHIL, WILL THAT BE OK
WITH

1169
00:49:22,640 --> 00:49:22,880
YOU?

1170
00:49:22,880 --> 00:49:26,920
>>THAT'S FINE.

1171
00:49:26,920 --> 00:49:27,440
ALL RIGHT.

1172
00:49:27,440 --> 00:49:35,200
WE CAN TALK ABOUT THIS IDEA.

1173
00:49:35,200 --> 00:49:39,120
SO I'M JUST GOING TO LIST THE

1174
00:49:39,120 --> 00:49:42,480
OTHER ONES.

1175
00:49:42,480 --> 00:49:43,560
PHIL THEY PROBABLY COL HAVE IT

1176
00:49:43,560 --> 00:49:45,200
IN THREE MONTHS SO THAT'S WHY I

1177
00:49:45,200 --> 00:49:47,480
THINK THIS TIMELINESS IS GOOD

1178
00:49:47,480 --> 00:49:51,600
AND HOW LONG YOU THINK YOU WOULD

1179
00:49:51,600 --> 00:49:52,920
NEED FOR THIS, PHIL.

1180
00:49:52,920 --> 00:49:54,200
THE WHOLE TIME?

1181
00:49:54,200 --> 00:49:58,880
WE HAVE ABOUT AN HOUR?

1182
00:49:58,880 --> 00:50:00,440
>>LET'S KEEP IT WITHIN A

1183
00:50:00,440 --> 00:50:04,280
HALF-HOUR SO YOU CAN DO OTHER

1184
00:50:04,280 --> 00:50:04,960
SUBCOMMITTEE BUSINESS.

1185
00:50:04,960 --> 00:50:08,120
WE CAN GET TO THE START OF

1186
00:50:08,120 --> 00:50:09,600
THINGS IN 30 MINUTES AND HAVE 10

1187
00:50:09,600 --> 00:50:11,080
MINUTES OF DISCUSSION?

1188
00:50:11,080 --> 00:50:11,240
>>

1189
00:50:11,240 --> 00:50:13,600
>>I'M NOT SURE WITH THIS
GROUP.

1190
00:50:13,600 --> 00:50:14,000
 [LAUGHTER] 

1191
00:50:14,000 --> 00:50:15,880
>>IF YOU WANT TO GIVE US
MORE

1192
00:50:15,880 --> 00:50:18,160
TIME HOW ABOUT 30 MINUTES OF

1193
00:50:18,160 --> 00:50:20,840
REPRESENTATION AND 15 MINUTES OF

1194
00:50:20,840 --> 00:50:21,160
DISCUSSION.

1195
00:50:21,160 --> 00:50:26,560
>>AND WE CAN SORT OF TALK
ABOUT

1196
00:50:26,560 --> 00:50:29,120
AND WHAT MAYBE I'LL DO WITH IN

1197
00:50:29,120 --> 00:50:35,040
HELP FROM NCI IS IN THE BACK

1198
00:50:35,040 --> 00:50:36,520
SORT OF TALK TO FOLKS ON THEIR

1199
00:50:36,520 --> 00:50:40,760
TAKE IF THEY'RE PLANNING TO DO

1200
00:50:40,760 --> 00:50:41,960
ANYTHING ABOUT THE SOCIAL

1201
00:50:41,960 --> 00:50:42,960
DETERMINANTS OF HEALTH THAT

1202
00:50:42,960 --> 00:50:50,360
KAREN RAISED AND ALSO THE ISSUE

1203
00:50:50,360 --> 00:50:54,600
OF CLIP CAL TRIAL A KUEHL DO WE

1204
00:50:54,600 --> 00:51:01,480
WANT TO LOOK AT THAT AND THE --

1205
00:51:01,480 --> 00:51:05,000
AND THEN THE EXTRAMURAL

1206
00:51:05,000 --> 00:51:06,440
ENGAGEMENT I'LL TALK WITH SOME

1207
00:51:06,440 --> 00:51:09,280
MORE FOLKS ABOUT THAT AND YOU

1208
00:51:09,280 --> 00:51:12,080
KNOW, HOW DO WE INCOMPETENT

1209
00:51:12,080 --> 00:51:16,840
GREAT EPI IN SURVEILLANCE OF

1210
00:51:16,840 --> 00:51:18,120
BRINGING THE DRUGS TO MARKET AND

1211
00:51:18,120 --> 00:51:21,880
HE WILL HOWARD THAT'S YOUR

1212
00:51:21,880 --> 00:51:22,320
COMMENT.

1213
00:51:22,320 --> 00:51:23,880
>>ELECTRA, ONE THING TO
THINK

1214
00:51:23,880 --> 00:51:26,160
ABOUT IS THERE ARE OTHER

1215
00:51:26,160 --> 00:51:26,840
SUBCOMMITTEES AS WELL.

1216
00:51:26,840 --> 00:51:28,600
THERE'S A CLINICAL

1217
00:51:28,600 --> 00:51:29,840
INVESTIGATIONS AND SO WE CAN

1218
00:51:29,840 --> 00:51:32,120
ALSO LOOK AT WHERE WE CAN SORT

1219
00:51:32,120 --> 00:51:36,160
OF AGAIN INTEGRATE ACROSS OUR

1220
00:51:36,160 --> 00:51:37,560
COMMITTEES OF WITH INFORMATION

1221
00:51:37,560 --> 00:51:42,240
SO THAT ONE GROUP ISN'T TRYING

1222
00:51:42,240 --> 00:51:43,680
TO TOO MUCH SO JUST CONSIDERING

1223
00:51:43,680 --> 00:51:44,000
THAT.

1224
00:51:44,000 --> 00:51:48,440
>>I'M BRINGING UP THE
MAJOR

1225
00:51:48,440 --> 00:51:50,760
TOPICS AND THEN MY IDEA IS TO

1226
00:51:50,760 --> 00:51:52,080
TALK TO YOU AND OTHER PEOPLE TO

1227
00:51:52,080 --> 00:51:54,600
FIGURE OUT WHERE IS THE BEST

1228
00:51:54,600 --> 00:51:57,600
PLACE AND THAT THESE WOULD FALL

1229
00:51:57,600 --> 00:52:01,160
NOT NECESSARILY IN THIS BUT

1230
00:52:01,160 --> 00:52:02,640
ELSEWHERE OR SHE IS ALREADY

1231
00:52:02,640 --> 00:52:04,720
DOING THAT THAT'S WHERE I'M

1232
00:52:04,720 --> 00:52:05,400
GOING.

1233
00:52:05,400 --> 00:52:10,480
BUT THE MAIN AREA WERE SOCIAL

1234
00:52:10,480 --> 00:52:14,440
DETERMINANTS OF HEALTH EX

1235
00:52:14,440 --> 00:52:20,880
SURVEILLANCE AND AND ANN'S POINT

1236
00:52:20,880 --> 00:52:27,040
ABOUT THE SCALING BIOLOGY, EPI

1237
00:52:27,040 --> 00:52:28,680
GENOMICS AND INTEGRATED APPROACH

1238
00:52:28,680 --> 00:52:37,320
TO POPULATION SCIENCE.

1239
00:52:37,320 --> 00:52:39,320
WE DO NEED TO KNOW HOW WE HEAR

1240
00:52:39,320 --> 00:52:41,000
BACK ON EVALUATION OF

1241
00:52:41,000 --> 00:52:42,720
SUPPLEMENTS SO IN OF THOSE ARE

1242
00:52:42,720 --> 00:52:44,680
JUST QUESTIONS THAT WE CAN ASK

1243
00:52:44,680 --> 00:52:48,200
AND REPORT BACK.

1244
00:52:48,200 --> 00:52:51,880
DOES THAT SOUND LIKE A PLAN,

1245
00:52:51,880 --> 00:52:52,160
EVERYBODY?

1246
00:52:52,160 --> 00:52:55,240
>>I HATE TO THROW ONE OUT
AT

1247
00:52:55,240 --> 00:52:55,520
END.

1248
00:52:55,520 --> 00:53:00,440
THIS IS A LOT GOING ON WITH THE,

1249
00:53:00,440 --> 00:53:02,560
K. AND WELCOME BACK OF THE AREAS

1250
00:53:02,560 --> 00:53:05,240
IS ENVIRONMENTAL CARCINOMA OWE

1251
00:53:05,240 --> 00:53:06,920
BEGINS AND THAT IS IS A

1252
00:53:06,920 --> 00:53:09,680
POPULATION BASED I THINK AREA OF

1253
00:53:09,680 --> 00:53:12,000
INTEREST TO THINK ABOUT.

1254
00:53:12,000 --> 00:53:13,480
ENVIRONMENTAL INFLUENCES AND

1255
00:53:13,480 --> 00:53:14,160
FACTORS.

1256
00:53:14,160 --> 00:53:17,440
THAT'S A POPULATION BASED I

1257
00:53:17,440 --> 00:53:17,840
THINK.

1258
00:53:17,840 --> 00:53:23,240
>>IT IS, IT'S EPI BUT IT
ALSO

1259
00:53:23,240 --> 00:53:23,880
INCOMPETENT GATES TOXICOLOGY AND

1260
00:53:23,880 --> 00:53:27,240
OTHER BASIC SCIENTISTS SO WE CAN

1261
00:53:27,240 --> 00:53:29,000
A IS SIS WHAT UPDATES ARE EX

1262
00:53:29,000 --> 00:53:32,920
WHAT IS GOING ON IN THAT AREA.

1263
00:53:32,920 --> 00:53:36,360
OK SO,  WE NEED UPDATES AND WHAT

1264
00:53:36,360 --> 00:53:37,240
IS GOING ON.

1265
00:53:37,240 --> 00:53:39,040
IF THIS IS APPROPRIATE FOR OUR

1266
00:53:39,040 --> 00:53:40,560
COMMITTEE OR IF IT'S ALREADY

1267
00:53:40,560 --> 00:53:49,400
BEING UNDERTAKE EP BY NCI.

1268
00:53:49,400 --> 00:53:51,520
>>ALL RIGHT.

1269
00:53:51,520 --> 00:53:53,640
DOES THIS SOUPED OK TO

1270
00:53:53,640 --> 00:53:54,440
EVERYBODY?

1271
00:53:54,440 --> 00:53:57,800
I THINK WE WILL NEED A GOOD

1272
00:53:57,800 --> 00:53:58,920
AMOUNT OF TIME TO HEAR THE

1273
00:53:58,920 --> 00:54:02,120
REPORT AND I REALLY DO AND I

1274
00:54:02,120 --> 00:54:04,080
THINK IT'S GOING TO BE VERY

1275
00:54:04,080 --> 00:54:06,440
IMPACTFUL AND ACTUALLY SHOW GAPS

1276
00:54:06,440 --> 00:54:07,880
AND THEN WITH ALL OF THE THINGS

1277
00:54:07,880 --> 00:54:10,960
THAT WE ASKED YOU TO ADD ON TO.

1278
00:54:10,960 --> 00:54:13,440
I MEAN THAT MIGHT ADD A LOT OF

1279
00:54:13,440 --> 00:54:14,080
TIME.

1280
00:54:14,080 --> 00:54:16,000
THIS WILL BE A REALLY MEANINGFUL

1281
00:54:16,000 --> 00:54:17,800
AND THEM WE CAN DECIDE IF WE

1282
00:54:17,800 --> 00:54:21,200
WANT TO MOVE IN THAT SPACE OR

1283
00:54:21,200 --> 00:54:22,440
JUST EP DOERS, YOU KNOW, SORT OF

1284
00:54:22,440 --> 00:54:24,440
WHAT YOU FOUND AND DECIDE WHERE

1285
00:54:24,440 --> 00:54:25,640
WE WANT TO GO.

1286
00:54:25,640 --> 00:54:28,840
AND I'LL TRY TO GET SOME UPDATES

1287
00:54:28,840 --> 00:54:32,000
OF THESE OTHER THINGS IN TERMS

1288
00:54:32,000 --> 00:54:34,400
OF THEY'RE BEING DONE BY NCI OR

1289
00:54:34,400 --> 00:54:35,440
OTHERS OR IF THEY BUILDING IN

1290
00:54:35,440 --> 00:54:36,800
OTHER SUBCOMMITTEES OR THEY'RE

1291
00:54:36,800 --> 00:54:43,680
STILL ON THE DOCKET FOR US.

1292
00:54:43,680 --> 00:54:46,120
SOUNDS GOOD?

1293
00:54:46,120 --> 00:54:48,200
I THINK WE HAD A GREAT, GREAT

1294
00:54:48,200 --> 00:54:48,960
SUBCOMMITTEE MEETING.

1295
00:54:48,960 --> 00:54:51,800
THANK YOU ALL FOR ATTENDING AND

1296
00:54:51,800 --> 00:54:55,280
FOR YOUR WONDERFUL

1297
00:54:55,280 --> 00:54:56,080
PARTICIPATION.

1298
00:54:56,080 --> 00:55:00,400
YOU CAN ARE A FIVE-MINUTE -- A

1299
00:55:00,400 --> 00:55:03,040
10 MINUTE BREAK ACCORDING TO THE

1300
00:55:03,040 --> 00:55:03,480
CALENDER.

1301
00:55:03,480 --> 00:55:06,160
THE AGENDA, BEFORE WE START THE

1302
00:55:06,160 --> 00:55:08,360
PLANNING AND BUDGET IS

1303
00:55:08,360 --> 00:55:09,160
SUBCOMMITTEE.

1304
00:55:09,160 --> 00:55:13,200
ARE WE TO JUST STAY ON HERE?

1305
00:55:13,200 --> 00:55:15,360
>>YES, YES.

1306
00:55:15,360 --> 00:55:15,720
ALL RIGHT.

1307
00:55:15,720 --> 00:55:17,320
THANK YOU, EVERYBODY.

1308
00:55:17,320 --> 00:55:18,600
TAKE CARE.

1309
00:55:18,600 --> 00:55:18,840
BE WELL.

1310
00:55:18,840 --> 00:55:21,600
>>THANK YOU, ELECTRA.

1311
00:55:21,600 --> 00:55:31,920
OUTSTANDING MEETING.

1312
00:55:36,080 --> 00:55:36,920
>>THIS IS A PUBLIC

1313
00:55:36,920 --> 00:55:38,680
MEETING THAT IS IS BEING VIDEO

1314
00:55:38,680 --> 00:55:40,240
CAST AND RECORDED.

1315
00:55:40,240 --> 00:55:41,600
MEMBERS OF THE PUBLIC WHO MAY

1316
00:55:41,600 --> 00:55:43,360
WISH TO EXPRESS VIEWS REGARDING

1317
00:55:43,360 --> 00:55:44,840
ANY ITEMS DISCUSSED DURING THIS

1318
00:55:44,840 --> 00:55:51,480
MEETING MAY DO SO BY WRITE TO GO

1319
00:55:51,480 --> 00:55:52,360
PAULA GRAY WITHIN 10 DAYS AFTER

1320
00:55:52,360 --> 00:55:53,680
THE MEETING.

1321
00:55:53,680 --> 00:55:54,680
ANY WRITTEN STATEMENTS OR

1322
00:55:54,680 --> 00:55:56,200
QUESTIONS SUBMITTED BY MEMBERS

1323
00:55:56,200 --> 00:55:57,480
OF THE PUBLIC WILL RECEIVE

1324
00:55:57,480 --> 00:56:01,680
CAREFUL CONSIDERATION.

1325
00:56:01,680 --> 00:56:03,120
THE FOLLOWING NCAB MEMBERS ARE

1326
00:56:03,120 --> 00:56:03,640
PARTICIPATING TODAY.

1327
00:56:03,640 --> 00:56:10,440
THE CHAIR Dr. BARKER, Dr.

1328
00:56:10,440 --> 00:56:11,960
AND Dr. PASKETT.

1329
00:56:11,960 --> 00:56:14,240
ARE THERE ANY QUESTIONS

1330
00:56:14,240 --> 00:56:14,760
REGARDING PROCESS?

1331
00:56:14,760 --> 00:56:16,280
Dr. BARKER, YOU MAY NOW BEGIN

1332
00:56:16,280 --> 00:56:17,000
THE MEETING.

1333
00:56:17,000 --> 00:56:18,960
>>THANK YOU, VERY MUCH,
JOY.

1334
00:56:18,960 --> 00:56:20,080
AND WELCOME.

1335
00:56:20,080 --> 00:56:21,600
THIS IS OUR FIRST MEETING FOR

1336
00:56:21,600 --> 00:56:25,480
THIS SUBCOMMITTEE IN 2023.

1337
00:56:25,480 --> 00:56:27,080
IT SEEMS LIKE A LONG TIME AND A

1338
00:56:27,080 --> 00:56:28,480
LOT HAS HAPPENED IN THE LAST

1339
00:56:28,480 --> 00:56:33,200
SELF MONTHS SINCE WE LAST MET.

1340
00:56:33,200 --> 00:56:36,400
INCLUDING OBVIOUSLY OUR NEW NCI

1341
00:56:36,400 --> 00:56:37,640
DIRECTOR AND THANK YOU Dr.

1342
00:56:37,640 --> 00:56:38,520
BERTAGNOLLI FOR JOINING US

1343
00:56:38,520 --> 00:56:38,960
TODAY.

1344
00:56:38,960 --> 00:56:42,520
WE KNOW HER AS MONICA, SO I WILL

1345
00:56:42,520 --> 00:56:46,760
FOURTH WITH CALL HER MONICA.

1346
00:56:46,760 --> 00:56:48,640
WE APPRECIATE YOU JOINING TODAY,

1347
00:56:48,640 --> 00:56:51,440
MONICA, THERE'S A LOT GOING ON.

1348
00:56:51,440 --> 00:56:54,160
SO, I'M NOT GOING TO SAY A LOT,

1349
00:56:54,160 --> 00:56:56,320
BUT IF YOU ATTENDED THE LAST

1350
00:56:56,320 --> 00:56:57,720
SUBCOMMITTEE MEETING I THINK

1351
00:56:57,720 --> 00:57:00,080
ELECTRA DID A FABULOUS JOB OF

1352
00:57:00,080 --> 00:57:02,160
RECASTING THE COMMITTEE,

1353
00:57:02,160 --> 00:57:03,000
REMINDING EVERYONE WHAT THE

1354
00:57:03,000 --> 00:57:04,480
CHARGES WAS AND IT OCCURRED TO

1355
00:57:04,480 --> 00:57:05,960
ME THAT WOULD BE A GOOD IDEA FOR

1356
00:57:05,960 --> 00:57:06,640
THIS COMMITTEE.

1357
00:57:06,640 --> 00:57:09,760
THIS IS NOT AN EASY COMMITTEE TO

1358
00:57:09,760 --> 00:57:10,480
UNDERSTAND.

1359
00:57:10,480 --> 00:57:12,760
WE CAN'T REALLY COME UP WITH

1360
00:57:12,760 --> 00:57:13,760
SCIENTIFIC IDEAS, WE'RE TRYING

1361
00:57:13,760 --> 00:57:14,920
TO THINK ABOUT HOW CAN WE HELP

1362
00:57:14,920 --> 00:57:20,640
THE NCI MOST IN TERMS OF OUR

1363
00:57:20,640 --> 00:57:23,200
PLANNING AND BUDGET PROCESS.

1364
00:57:23,200 --> 00:57:25,480
THE PURPOSE OF THIS IS TO ASSIST

1365
00:57:25,480 --> 00:57:28,840
OF THE DIRECTOR, NCI, AND IT

1366
00:57:28,840 --> 00:57:29,560
SAYS, HISS STAFF HERE WILL

1367
00:57:29,560 --> 00:57:33,960
CHANGE THAT NOW TO HER STAFF.

1368
00:57:33,960 --> 00:57:36,120
ACTUALLY DOES SAY HIS STAFF.

1369
00:57:36,120 --> 00:57:37,840
ON ISSUES INVOLVING THE BUDGET

1370
00:57:37,840 --> 00:57:39,920
PROCESS AND PLANNING FOR THE

1371
00:57:39,920 --> 00:57:42,720
NATIONAL CANCER PROGRAM.

1372
00:57:42,720 --> 00:57:45,760
SO THAT'S A LITTLE DIFFERENT

1373
00:57:45,760 --> 00:57:46,960
READING OF THE NCI.

1374
00:57:46,960 --> 00:57:48,520
SO THE SUBCOMMITTEE PROVIDES

1375
00:57:48,520 --> 00:57:50,440
ADVICE ON THE BUDGET PROCESS BY

1376
00:57:50,440 --> 00:57:54,440
COMMENTING ON THE PRESENCE

1377
00:57:54,440 --> 00:58:04,960
BUDGET AND THAT OUR CHARGE AND

1378
00:58:10,960 --> 00:58:13,200
IT'S NOT THAT THE NCI DOESN'T

1379
00:58:13,200 --> 00:58:15,240
HAVE A PLANNING PROCESS OR A

1380
00:58:15,240 --> 00:58:17,120
BUDGET, IT HAS SEVERAL AND SO

1381
00:58:17,120 --> 00:58:18,520
SOMETIMES IT GETS A LITTLE

1382
00:58:18,520 --> 00:58:19,040
CONFUSING.

1383
00:58:19,040 --> 00:58:22,800
BECAUSE WE DO HAVE THE NCI TO

1384
00:58:22,800 --> 00:58:24,440
BUDGET EVERY YEAR THAT'S

1385
00:58:24,440 --> 00:58:25,600
REALISTIC EXPECTATIONS OF THAT

1386
00:58:25,600 --> 00:58:26,400
PARTICULAR YEAR.

1387
00:58:26,400 --> 00:58:28,200
WE SUBMIT THAT AND THEN THE

1388
00:58:28,200 --> 00:58:30,000
PRESIDENT LOOKS AT THAT AND HE

1389
00:58:30,000 --> 00:58:31,640
CREATES A BUDGET OR SHE CREATES

1390
00:58:31,640 --> 00:58:35,520
A BUDGET AND THEN THE NEXT PIECE

1391
00:58:35,520 --> 00:58:37,320
IT ALL GOES TO CONGRESS AND THEN

1392
00:58:37,320 --> 00:58:42,280
YOU KNOW, NOW, WE HAVE A FEW NO

1393
00:58:42,280 --> 00:58:43,880
KNOWNS IN THIS PROCESS, WE HAVE

1394
00:58:43,880 --> 00:58:46,120
A LOT OF KNOWN UNKNOWNS AND WE

1395
00:58:46,120 --> 00:58:50,600
HAVE EVEN MORE UNKNOWN UNKNOWNS.

1396
00:58:50,600 --> 00:58:52,800
IT'S A PROCESS.

1397
00:58:52,800 --> 00:58:55,800
AND I WAS AT THE NIXSON LIBRARY

1398
00:58:55,800 --> 00:58:57,320
THIS YEAR FOR THE CELEBRATION OF

1399
00:58:57,320 --> 00:59:04,520
THE NATIONAL CANCER AGENT AND

1400
00:59:04,520 --> 00:59:05,520
RICHARD NIXSON SAID IN AN

1401
00:59:05,520 --> 00:59:07,000
INTERVIEW AS HE WAS EXITING HIS

1402
00:59:07,000 --> 00:59:09,160
TERM IN OFFICE, NOT A HAPPY

1403
00:59:09,160 --> 00:59:10,560
ENDING BUT, HE SAID HE THOUGHT

1404
00:59:10,560 --> 00:59:12,320
THE MOST IMPACTFUL THING HE HAD

1405
00:59:12,320 --> 00:59:14,480
DONE IN OFFICE WAS THE NATIONAL

1406
00:59:14,480 --> 00:59:15,520
CANCER ACT.

1407
00:59:15,520 --> 00:59:18,520
AND AS YOU RECALL IF YOU SAW THE

1408
00:59:18,520 --> 00:59:20,040
PRESIDENT'S ADDRESS THE NIGHT

1409
00:59:20,040 --> 00:59:22,440
BEFORE LAST, HE IS INTERESTED IN

1410
00:59:22,440 --> 00:59:23,880
REAUTHORIZATION THE NATIONAL

1411
00:59:23,880 --> 00:59:25,040
CANCER ACT.

1412
00:59:25,040 --> 00:59:27,880
AND WE'VE BEEN TALKING ABOUT

1413
00:59:27,880 --> 00:59:29,440
THAT FOR A LONG TIME, A COUPLE

1414
00:59:29,440 --> 00:59:31,320
OF DECADES, AND IF YOU GO BACK

1415
00:59:31,320 --> 00:59:33,000
TO THE ORIGINAL NATIONAL CANCER

1416
00:59:33,000 --> 00:59:36,480
ACT, YOU WOULD SEE THAT IT IS

1417
00:59:36,480 --> 00:59:38,360
REAUTHORIZED AND THERE WOULD BE

1418
00:59:38,360 --> 00:59:39,840
SOME CHANGES THAT WOULD BE VERY

1419
00:59:39,840 --> 00:59:41,280
INTERESTING I THINK IN TERMS OF

1420
00:59:41,280 --> 00:59:42,440
SOME OF THE PROBLEMS THAT WE'RE

1421
00:59:42,440 --> 00:59:44,360
FACING IN CANCER.

1422
00:59:44,360 --> 00:59:48,040
SO, A LOT OF GOOD NEWS.

1423
00:59:48,040 --> 00:59:49,640
I LIKE TO DELIVER GOOD NEWS.

1424
00:59:49,640 --> 00:59:52,920
WE SAW THE REPORT THAT CAME OUT

1425
00:59:52,920 --> 00:59:55,640
FROM ACS RECENTLY, 33% DECLINE

1426
00:59:55,640 --> 00:59:57,520
IN MORTALITY RATE FOR ALL

1427
00:59:57,520 --> 01:00:00,800
CANCERS WHICH HAS BEEN ACHIEVED

1428
01:00:00,800 --> 01:00:02,560
OVER SEVERAL DECADES NOW AND I

1429
01:00:02,560 --> 01:00:06,920
HAVE TO SAY, IT'S PRETTY

1430
01:00:06,920 --> 01:00:16,040
IMPRESSIVE.

1431
01:00:16,040 --> 01:00:17,400
AND WE'RE SEEING THE IMPACT

1432
01:00:17,400 --> 01:00:18,760
WE'RE STARTING AND IT'S HAVING

1433
01:00:18,760 --> 01:00:20,840
AN IMPACT AND I THINK THAT CURVE

1434
01:00:20,840 --> 01:00:23,440
IS STARTED ING TO GO UP.

1435
01:00:23,440 --> 01:00:29,760
BUT IN THIS POINT IN TIME, A LOT

1436
01:00:29,760 --> 01:00:30,920
OF THAT HAVE -- INCREASE IN

1437
01:00:30,920 --> 01:00:33,680
MORTALITY RATES IS DUE TO

1438
01:00:33,680 --> 01:00:34,440
SMOKING SECESSION WE'VE SEEN

1439
01:00:34,440 --> 01:00:35,720
ACROSS THE COUNTRY.

1440
01:00:35,720 --> 01:00:37,760
THIS IS WHAT WE'RE GOING TO DO.

1441
01:00:37,760 --> 01:00:38,800
THERE'S A BIG SURPRISE IN THAT

1442
01:00:38,800 --> 01:00:39,120
REPORT.

1443
01:00:39,120 --> 01:00:41,320
I DON'T THINK IT SHOULD BE A

1444
01:00:41,320 --> 01:00:41,800
SURPRISE.

1445
01:00:41,800 --> 01:00:45,600
ANYBODY KNOWS ME I'M A COMPLEX

1446
01:00:45,600 --> 01:00:47,000
ADAPTIVE SYSTEMS SCIENCE.

1447
01:00:47,000 --> 01:00:49,960
WHEN YOU PUSH ON ONE NODE IN

1448
01:00:49,960 --> 01:00:53,160
THIS SYSTEM IT REVERBERATES

1449
01:00:53,160 --> 01:00:54,080
THROUGH THE SYSTEM.

1450
01:00:54,080 --> 01:00:55,840
THREE OR FOUR YEARS A. WE SAID,

1451
01:00:55,840 --> 01:00:58,960
LET'S REALLY RETHINK PSH

1452
01:00:58,960 --> 01:00:59,840
SCREENING FOR PROSTATE CANCER

1453
01:00:59,840 --> 01:01:01,440
AND THAT'S WHAT WE DID AND ALL

1454
01:01:01,440 --> 01:01:04,680
OF A SUDDEN, WE HAVE THIS LATE

1455
01:01:04,680 --> 01:01:06,240
PROSTATE CANCER SHOWING UP AND

1456
01:01:06,240 --> 01:01:08,520
IT'S JUST DECIMATED OUR

1457
01:01:08,520 --> 01:01:09,960
MORTALITY CURVES AND PROSTATE

1458
01:01:09,960 --> 01:01:10,640
CANCER.

1459
01:01:10,640 --> 01:01:11,960
SO, WE HAVE TO THINK THIS

1460
01:01:11,960 --> 01:01:13,040
THROUGH AND WE HAD THIS

1461
01:01:13,040 --> 01:01:15,720
CONVERSATION IN THE LAST

1462
01:01:15,720 --> 01:01:16,520
SUBCOMMITTEE MEETING.

1463
01:01:16,520 --> 01:01:17,920
WHEN YOU PUSH ON ONE NODE IN

1464
01:01:17,920 --> 01:01:20,000
THIS SYSTEM YOU BETTER THINK

1465
01:01:20,000 --> 01:01:23,360
THROUGH WHAT ARE THE POTENTIAL

1466
01:01:23,360 --> 01:01:27,280
OUTCOMES OF MOVING SOMETHING

1467
01:01:27,280 --> 01:01:30,840
LIKE SCREENING.

1468
01:01:30,840 --> 01:01:36,080
OPENED,SCREENING.THE OPPORTUNITG

1469
01:01:36,080 --> 01:01:37,560
RIGHT NOW ON THE OTHER HAND.

1470
01:01:37,560 --> 01:01:39,040
I MENTIONED ONE IN THE

1471
01:01:39,040 --> 01:01:40,400
SUBCOMMITTEE A FEW MINUTES AGO.

1472
01:01:40,400 --> 01:01:42,720
WE HAVE THOUGHT FOR A LONG TIME

1473
01:01:42,720 --> 01:01:44,880
THAT THE EPI GENOME IS IMPORTANT

1474
01:01:44,880 --> 01:01:45,960
BUT WE HAVEN'T KNOWN WHETHER OR

1475
01:01:45,960 --> 01:01:49,040
NOT IT CAN BE ACTUALLY

1476
01:01:49,040 --> 01:01:49,600
TRANSFERRED THROUGH THE GERM

1477
01:01:49,600 --> 01:01:49,800
LINE.

1478
01:01:49,800 --> 01:01:50,760
IT TURNS OUT THAT IT PROBABLY

1479
01:01:50,760 --> 01:01:51,000
CAN.

1480
01:01:51,000 --> 01:01:52,680
I MEAN, THIS REPORT THAT CAME

1481
01:01:52,680 --> 01:01:57,360
OUT THIS WEEK IS CONVINCING.

1482
01:01:57,360 --> 01:02:00,600
THIS HAPPENED TO DEAL WELL

1483
01:02:00,600 --> 01:02:02,040
METABALOMICS AND IF IT'S TRUE IT

1484
01:02:02,040 --> 01:02:03,080
COULD EXPLAIN A LOT.

1485
01:02:03,080 --> 01:02:05,720
IT COULD REALLY EXPLAIN A LOT.

1486
01:02:05,720 --> 01:02:06,280
IT WOULD CHANGE THE WAY WE

1487
01:02:06,280 --> 01:02:06,480
THINK.

1488
01:02:06,480 --> 01:02:09,280
WE HAVE MULTIPLE EARLY DETECTION

1489
01:02:09,280 --> 01:02:12,200
FOR CANCER WHICH IS TAKING OFF.

1490
01:02:12,200 --> 01:02:17,480
LIKE IT OR NOT IT'S TAKING OFF.

1491
01:02:17,480 --> 01:02:18,520
AND BEYOND THE GRAIL THAT ARE

1492
01:02:18,520 --> 01:02:20,080
TENS IF NOT 20s OF COMPANIES

1493
01:02:20,080 --> 01:02:21,640
THAT ARE ACTUALLY PURSUING THIS

1494
01:02:21,640 --> 01:02:23,040
IDEA.

1495
01:02:23,040 --> 01:02:25,840
SO, A LOT OF THINGS GOING ON AND

1496
01:02:25,840 --> 01:02:28,080
A LOT OF I THINK REALLY

1497
01:02:28,080 --> 01:02:29,560
INTERESTING ADVANCES THAT COULD

1498
01:02:29,560 --> 01:02:33,360
CHANGE THESE FEATURE STATISTICS

1499
01:02:33,360 --> 01:02:37,440
IN VERY MEANINGFUL WAYS.

1500
01:02:37,440 --> 01:02:39,200
I WOULD STEP BACK FROM THIS AND

1501
01:02:39,200 --> 01:02:41,640
I THINK WHAT CAN THIS COMMITTEE

1502
01:02:41,640 --> 01:02:42,120
DO?

1503
01:02:42,120 --> 01:02:43,360
THAT'S WHAT WE HOPE TO HAVE A

1504
01:02:43,360 --> 01:02:45,040
LITTLE TIME TO TALK WITH YOU

1505
01:02:45,040 --> 01:02:48,960
ABOUT AT THE END AFTER WE GET

1506
01:02:48,960 --> 01:02:50,160
THROUGH A COUPLE PRESENTATIONS

1507
01:02:50,160 --> 01:02:54,520
WHICH ARE REALLY QUITE

1508
01:02:54,520 --> 01:02:55,880
INTERESTING.

1509
01:02:55,880 --> 01:02:56,600
I'M THINKING ABOUT THE FUTURE.

1510
01:02:56,600 --> 01:02:58,640
I HAVE MAJOR CONCERNS FOR THE

1511
01:02:58,640 --> 01:03:01,480
CANCER INSTITUTE RIGHT NOW.

1512
01:03:01,480 --> 01:03:04,880
AS MUCH AS THAT 33% DECLINE IN

1513
01:03:04,880 --> 01:03:06,960
MORTALITY IS REALLY IMPORTANT,

1514
01:03:06,960 --> 01:03:09,000
IF YOU LOOK AT NUMBERS OF CASES,

1515
01:03:09,000 --> 01:03:10,960
THEY'RE GOING TO CONTINUE TO GO

1516
01:03:10,960 --> 01:03:11,560
UP.

1517
01:03:11,560 --> 01:03:12,880
AS THE POPULATION IS AGING AND

1518
01:03:12,880 --> 01:03:14,320
NOT JUST IN THIS COUNTRY BUT

1519
01:03:14,320 --> 01:03:16,000
IT'S GOING TO BE A GLOBAL

1520
01:03:16,000 --> 01:03:16,680
CRISIS.

1521
01:03:16,680 --> 01:03:19,360
I THINK THIS IS GOING TO BE ONE

1522
01:03:19,360 --> 01:03:23,680
OF THE ALL-TIME (INAUDIBLE).

1523
01:03:23,680 --> 01:03:25,920
AND EVERYBODY KNOWS THAT THERE

1524
01:03:25,920 --> 01:03:28,800
ARE COUNTRIES THAT ARE JUST NOW

1525
01:03:28,800 --> 01:03:30,080
ENTERING A POINT WHERE THEY HAVE

1526
01:03:30,080 --> 01:03:31,720
CONTROLLED A LOT OF THE

1527
01:03:31,720 --> 01:03:33,040
INFECTIOUS AGENTS THAT THEY'VE

1528
01:03:33,040 --> 01:03:34,440
DEALT WITH FOR DECADES AND NOW

1529
01:03:34,440 --> 01:03:36,160
THEY'RE DEALING WITH CANCER AND

1530
01:03:36,160 --> 01:03:37,920
WHEN YOU THINK ABOUT THAT ON A

1531
01:03:37,920 --> 01:03:40,560
GLOBAL BASIS, IT'S GOING TO BE

1532
01:03:40,560 --> 01:03:42,440
PARALYZING AND I WOULD IMAGINE,

1533
01:03:42,440 --> 01:03:44,040
THAT THERE ARE COUNTRY OUT THERE

1534
01:03:44,040 --> 01:03:45,080
RIGHT NOW THAT ARE BEGINNING TO

1535
01:03:45,080 --> 01:03:46,400
LOOK AT THAT AND REALIZE THAT

1536
01:03:46,400 --> 01:03:47,680
THEY HAVE A LARGE POPULATIONS

1537
01:03:47,680 --> 01:03:50,520
THAT ARE GOING TO ACTUALLY --

1538
01:03:50,520 --> 01:03:51,640
THE HEALTHCARE COSTS ALONE ARE

1539
01:03:51,640 --> 01:03:53,360
GOING TO EAT THEM ALIVE AND

1540
01:03:53,360 --> 01:03:54,560
THEY'RE GOING TO BE HARD-PRESSED

1541
01:03:54,560 --> 01:03:56,720
TO KEEP THEIR ECONOMY GOING.

1542
01:03:56,720 --> 01:03:59,520
I THINK WE NEED TO THINK ABOUT

1543
01:03:59,520 --> 01:04:00,800
THAT, REALLY LONG AND HARD IN

1544
01:04:00,800 --> 01:04:02,320
THIS COMMITTEE BECAUSE THE

1545
01:04:02,320 --> 01:04:04,160
PRESIDENT IS THINKING ABOUT THIS

1546
01:04:04,160 --> 01:04:08,480
AND HE IS NOT TO BE DETERRED ON

1547
01:04:08,480 --> 01:04:09,840
HIS CONCERNS FOR DOING MORE

1548
01:04:09,840 --> 01:04:11,280
ABOUT CAP SER AND I THINK WE

1549
01:04:11,280 --> 01:04:12,680
SHOULD DO EVERYTHING POSSIBLE

1550
01:04:12,680 --> 01:04:14,480
THAT WE CAN TO DELIVER FOR HIM

1551
01:04:14,480 --> 01:04:17,000
AND FOR OUR COUNTRY AND FOR THE

1552
01:04:17,000 --> 01:04:17,200
WORLD.

1553
01:04:17,200 --> 01:04:19,120
SO, NCI AT THE CENTER OF THE

1554
01:04:19,120 --> 01:04:20,920
UNIVERSE HERE, IN MY OPINION,

1555
01:04:20,920 --> 01:04:22,680
AND I THINK THIS COMMITTEE COULD

1556
01:04:22,680 --> 01:04:23,920
HELP A LOT IN TERMS OF HOW WE

1557
01:04:23,920 --> 01:04:25,360
CAN THINK ABOUT THE FUTURE AND

1558
01:04:25,360 --> 01:04:29,120
HOW WE CAN THICK ABOUT GETTING

1559
01:04:29,120 --> 01:04:30,560
THE KINDS OF RESOURCE WE SEE

1560
01:04:30,560 --> 01:04:32,120
NEED TO FUND THE KIND OF

1561
01:04:32,120 --> 01:04:33,600
RESEARCH THAT WE THINK ABOUT AND

1562
01:04:33,600 --> 01:04:35,480
TALK ABOUT THAT ARE GOING TO BE

1563
01:04:35,480 --> 01:04:38,640
REQUIRED TO CHANGE THESE CURVES,

1564
01:04:38,640 --> 01:04:43,960
EVEN REMOTELY TO REACH THE KIND

1565
01:04:43,960 --> 01:04:45,440
OF GOAL HE SET FOR US AND THE

1566
01:04:45,440 --> 01:04:47,600
NATIONAL CANCER PROGRAM.

1567
01:04:47,600 --> 01:04:49,240
SO, I'LL GET OFF MY SOAP BOX

1568
01:04:49,240 --> 01:04:50,320
NOW.

1569
01:04:50,320 --> 01:04:51,360
I REEL THINK IT'S IMPORTANT THAT

1570
01:04:51,360 --> 01:04:54,320
WE TAKE THE COMMITTEES VERY

1571
01:04:54,320 --> 01:04:57,080
SERIOUSLY AND WORK WITH THE NCI,

1572
01:04:57,080 --> 01:04:59,760
MAKE RECOMMENDATIONS, COME UP

1573
01:04:59,760 --> 01:05:01,640
WITH IDEAS TO HELP TO PLAN A

1574
01:05:01,640 --> 01:05:04,840
ESPECIALLY FOR NOT JUST THE NEXT

1575
01:05:04,840 --> 01:05:07,000
TWO TO THREE YEARS BUT THE NEXT

1576
01:05:07,000 --> 01:05:08,080
COUPLE OF DECADES.

1577
01:05:08,080 --> 01:05:09,280
THAT'S THE KIND OF PLANNING WE

1578
01:05:09,280 --> 01:05:10,800
NEED HERE AND IT'S HARD BECAUSE

1579
01:05:10,800 --> 01:05:12,480
WE'RE FUNDED YEAR TO YEAR AT THE

1580
01:05:12,480 --> 01:05:14,160
NCI AND IT MAKES IT DIFFICULT

1581
01:05:14,160 --> 01:05:16,520
FOR EVERY DIRECTOR HAS BEEN IN

1582
01:05:16,520 --> 01:05:18,440
THIS CHAIR.

1583
01:05:18,440 --> 01:05:21,360
I THINK ESPECIALLY NOW.

1584
01:05:21,360 --> 01:05:24,480
SO, WITH THAT, LET ME SAY THAT

1585
01:05:24,480 --> 01:05:26,400
WE HAVE PATRICK McGAREY WITH

1586
01:05:26,400 --> 01:05:29,400
US TODAY WHO IS GOING TO -- HE

1587
01:05:29,400 --> 01:05:33,280
DOES SUCH A FABULOUS JOB AS THE

1588
01:05:33,280 --> 01:05:35,760
EXECUTIVE SECRETARY BUT I HAVE

1589
01:05:35,760 --> 01:05:37,160
AN ANNOUNCEMENT GOOD FOR PATRICK

1590
01:05:37,160 --> 01:05:40,120
AND BAD FOR US, PATRICK IS IS

1591
01:05:40,120 --> 01:05:41,080
RETIRING.

1592
01:05:41,080 --> 01:05:42,240
I CAN'T IMAGINE THAT HE IS IS

1593
01:05:42,240 --> 01:05:43,880
BUT HE IS AND YOU KNOW, WE'RE

1594
01:05:43,880 --> 01:05:45,600
GOING TO -- I'M GOING TO ASK

1595
01:05:45,600 --> 01:05:48,160
THIS COMMITTEE PAY HIM A GREAT

1596
01:05:48,160 --> 01:05:49,160
DEAL MORE TO STAY BUT I DON'T

1597
01:05:49,160 --> 01:05:51,120
THINK IT WILL CONVINCE HIM.

1598
01:05:51,120 --> 01:05:52,480
PATRICK, I HAVE TO SAY IS ONE OF

1599
01:05:52,480 --> 01:05:54,520
THE MOST DEDICATED PUBLIC

1600
01:05:54,520 --> 01:05:57,440
SERVANTS I'VE KNOWN.

1601
01:05:57,440 --> 01:06:00,120
HE IS 13 YEARS -- TWO DECADES ON

1602
01:06:00,120 --> 01:06:01,600
THE HILL.

1603
01:06:01,600 --> 01:06:07,840
HE THOSE HIS WAY AROUND T KNOWSE

1604
01:06:07,840 --> 01:06:10,720
POLITICS AND THE POLITICAL

1605
01:06:10,720 --> 01:06:14,520
REGIME AND 13 YEARS AT FDA SO HE

1606
01:06:14,520 --> 01:06:16,120
KNOWS THE REGULATORY AND 10

1607
01:06:16,120 --> 01:06:17,200
YEARS FOR NCI.

1608
01:06:17,200 --> 01:06:18,840
I CAN'T TELL WHAT YOU A GIFT

1609
01:06:18,840 --> 01:06:21,080
YOU'VE BEEN TO THIS SUBCOMMITTEE

1610
01:06:21,080 --> 01:06:23,120
AND HOW YOU HAVE KEPT US SO

1611
01:06:23,120 --> 01:06:26,120
INFORMED AND THE WHOLE OF THE

1612
01:06:26,120 --> 01:06:27,880
NCIB AND WE WISH YOU WELL AND WE

1613
01:06:27,880 --> 01:06:28,880
KNOW YOU WOULDN'T RETIRE AND YOU

1614
01:06:28,880 --> 01:06:30,560
WILL HAVE EXCITING THINGS TO DO

1615
01:06:30,560 --> 01:06:32,560
WITH YOUR LIFE, I'M SURE, AND WE

1616
01:06:32,560 --> 01:06:34,720
HOPE YOU WILL STAY IN TOUCH.

1617
01:06:34,720 --> 01:06:38,480
GIVE US ADVICE WHEN WE REALLY

1618
01:06:38,480 --> 01:06:39,360
NEED IT.

1619
01:06:39,360 --> 01:06:40,880
I'LL STOP THERE AND TURN IT OVER

1620
01:06:40,880 --> 01:06:42,360
TO PATRICK WHO WILL TELL US

1621
01:06:42,360 --> 01:06:45,440
ABOUT SOME OF THE KNOWN KNOWNS

1622
01:06:45,440 --> 01:06:47,560
AND A LOT OF KNOWN UNKNOWNS AND

1623
01:06:47,560 --> 01:06:49,800
QUITE A BIT ON THE UNKNOWN

1624
01:06:49,800 --> 01:06:50,880
UNKNOWNS.

1625
01:06:50,880 --> 01:06:52,440
PATRICK, TAKE IT AWAY.

1626
01:06:52,440 --> 01:06:55,240
>>I WENT OFF TRACK.

1627
01:06:55,240 --> 01:06:57,360
THANK YOU, VERY MUCH, FOR THOSE

1628
01:06:57,360 --> 01:06:59,760
KIND REMARKS AND I SAY THE

1629
01:06:59,760 --> 01:07:03,200
GOVERNMENT SERVICE IS SO

1630
01:07:03,200 --> 01:07:06,520
REWARDING.

1631
01:07:06,520 --> 01:07:09,320
NCI REFLECTS THE BEST IN

1632
01:07:09,320 --> 01:07:09,640
GOVERNMENT.

1633
01:07:09,640 --> 01:07:11,440
I'M PLEASED THAT I COULD

1634
01:07:11,440 --> 01:07:12,520
CONTRIBUTE IN SOME WAY HERE OR

1635
01:07:12,520 --> 01:07:13,280
THERE.

1636
01:07:13,280 --> 01:07:14,480
I'M HAPPY TO STAY IN TOUCH.

1637
01:07:14,480 --> 01:07:16,880
THANK YOU, VERY MUCH FOR THOSE

1638
01:07:16,880 --> 01:07:18,080
KIND WORDS.

1639
01:07:18,080 --> 01:07:19,880
SO, LET'S DO JUMP IN.

1640
01:07:19,880 --> 01:07:21,360
IT'S GO AHEAD TO BE HERE BEFORE

1641
01:07:21,360 --> 01:07:23,000
THE SUBCOMMITTEE AGAIN.

1642
01:07:23,000 --> 01:07:24,880
I'M GOING TO KICKOFF

1643
01:07:24,880 --> 01:07:26,080
PRESENTATION ON THE BUDGET AND

1644
01:07:26,080 --> 01:07:32,040
MY NCI COLLEAGUE Dr. PALMARI

1645
01:07:32,040 --> 01:07:32,840
WILL FOLLOW WITH THE DISCUSSION

1646
01:07:32,840 --> 01:07:36,280
OF THE ANNUAL PLAN.

1647
01:07:36,280 --> 01:07:39,120
SO OUR AGENDA BEGINS WITH FISCAL

1648
01:07:39,120 --> 01:07:41,760
YEAR 2022, THE YEAR THAT CLOSED

1649
01:07:41,760 --> 01:07:42,160
LAST SEPTEMBER.

1650
01:07:42,160 --> 01:07:45,640
THEN I'LL MOVE ONTO THE NCI

1651
01:07:45,640 --> 01:07:52,640
BUDGET FOR 2023 AND 2024.

1652
01:07:52,640 --> 01:07:55,200
SO WHAT YOU ARE SEEING HERE

1653
01:07:55,200 --> 01:07:57,360
DISPLAYING THE HIGHLIGHTS OF THE

1654
01:07:57,360 --> 01:07:59,400
NCI MAJOR GRANT MECHANISMS, WE

1655
01:07:59,400 --> 01:08:02,840
WILL HAVE A FINAL GRANT COUNT ON

1656
01:08:02,840 --> 01:08:04,200
MARCH 9th, WHICH IS AN

1657
01:08:04,200 --> 01:08:05,560
IMPORTANT BUDGET DATE AND I'M

1658
01:08:05,560 --> 01:08:07,080
GOING TO TALK MORE ABOUT LATER

1659
01:08:07,080 --> 01:08:09,080
IN THE PRESENTATION.

1660
01:08:09,080 --> 01:08:11,280
BUT AS THINGS STAND NOW, OUR

1661
01:08:11,280 --> 01:08:14,600
GRANT COUNT WILL LIKELY EXCEED

1662
01:08:14,600 --> 01:08:17,720
7500 AWARDS FOR THE FIRST TIME.

1663
01:08:17,720 --> 01:08:20,000
MORE THAN HALF OF THESE AWARDS

1664
01:08:20,000 --> 01:08:25,520
ARE RO1 OR R37 GRANTS.

1665
01:08:25,520 --> 01:08:27,960
JUST A WORD ABOUT R37s, IF AN

1666
01:08:27,960 --> 01:08:30,120
EARLY STAGE INVESTIGATORS

1667
01:08:30,120 --> 01:08:32,240
APPLICATION, IT'S AN ESI AS WE

1668
01:08:32,240 --> 01:08:35,840
USE THE ACRONYM, RECEIVES A PEER

1669
01:08:35,840 --> 01:08:39,000
REVIEW SCORE MORE THAN OR BETTER

1670
01:08:39,000 --> 01:08:43,440
THAN OR EQUAL TO THE RO1 PAYLINE

1671
01:08:43,440 --> 01:08:45,480
THAN THOSE NOT ESI AWARDS ARE

1672
01:08:45,480 --> 01:08:51,360
ALLOWED TO CONVERT TO R37, MERIT

1673
01:08:51,360 --> 01:08:51,720
AWARDS.

1674
01:08:51,720 --> 01:08:54,000
RO1 AWARDS ARE FOR FIVE YEARS

1675
01:08:54,000 --> 01:08:57,280
AND R37 RUNS FOR TWO ADDITIONAL

1676
01:08:57,280 --> 01:08:59,160
YEARS OF GRANT FUNDING SOMETHING

1677
01:08:59,160 --> 01:09:01,840
I'LL ALSO RETURN TO LATER

1678
01:09:01,840 --> 01:09:03,160
BECAUSE THAT'S TWO ADDITIONAL

1679
01:09:03,160 --> 01:09:06,400
YEARS OF NON COMPETING WHICH

1680
01:09:06,400 --> 01:09:09,120
WE'RE HAPPY O RESOURCE BUT THEY

1681
01:09:09,120 --> 01:09:11,480
HAVE BUDGET IMPLICATIONS.

1682
01:09:11,480 --> 01:09:14,480
SO WE EXPECT A STRONG YEAR FOR

1683
01:09:14,480 --> 01:09:18,440
OUR RO1, R37 AND R2 # NUMBERS21S

1684
01:09:18,440 --> 01:09:20,160
WITH INCREASED GRANT OUTPUT ON

1685
01:09:20,160 --> 01:09:20,840
ALL THREE.

1686
01:09:20,840 --> 01:09:25,840
THE R21s ARE THE EXPLORATORY

1687
01:09:25,840 --> 01:09:27,440
RESEARCH GRANTS.

1688
01:09:27,440 --> 01:09:29,160
PLEASE RECALL THAT 2022, THE

1689
01:09:29,160 --> 01:09:31,600
YEAR WE FINISHED AND THE YEAR

1690
01:09:31,600 --> 01:09:33,160
THAT THESE NUMBERS REFLECT, WAS

1691
01:09:33,160 --> 01:09:35,600
A YEAR WHEN WE HELD STEADY

1692
01:09:35,600 --> 01:09:37,960
RATHER THAN INCREASE THE

1693
01:09:37,960 --> 01:09:38,760
PAYLINES.

1694
01:09:38,760 --> 01:09:40,240
SO, I HOPE YOU CAN APPRECIATE

1695
01:09:40,240 --> 01:09:41,640
THAT EVEN IN A YEAR WHEN WE

1696
01:09:41,640 --> 01:09:44,400
DON'T INCREASE THE PAYLINES, WE

1697
01:09:44,400 --> 01:09:46,400
CAN STILL ISSUE SUBSTANTIALLY

1698
01:09:46,400 --> 01:09:50,440
MORE GRANTS WITH THE DOLLARS WE

1699
01:09:50,440 --> 01:09:58,160
HAVE.

1700
01:09:58,160 --> 01:10:00,720
LET ME TURN TO FY2023 AND THE

1701
01:10:00,720 --> 01:10:01,880
FISCAL YEAR WE BEGAN

1702
01:10:01,880 --> 01:10:02,640
OCTOBER 1st.

1703
01:10:02,640 --> 01:10:06,520
CONGRESS WAS VERY GOOD TO NCI

1704
01:10:06,520 --> 01:10:09,600
AND THIS YEAR WE WERE RECEIVING

1705
01:10:09,600 --> 01:10:11,240
$408 MILLION INCREASE OVER THE

1706
01:10:11,240 --> 01:10:13,160
PRIOR YEAR.

1707
01:10:13,160 --> 01:10:15,240
AND ONLY ONCE IN THE PAST 10

1708
01:10:15,240 --> 01:10:20,720
YEARS HAVE WE RECEIVED A HIGHER

1709
01:10:20,720 --> 01:10:23,680
PERCENTAGE INCREASE THAN THAT

1710
01:10:23,680 --> 01:10:24,160
5.9%.

1711
01:10:24,160 --> 01:10:27,200
THE INCREASE INCLUDES, WELCOME

1712
01:10:27,200 --> 01:10:31,160
BACK THE 408 THERE'S 22 MILLION

1713
01:10:31,160 --> 01:10:33,760
FOR THE CURES ACT MOONSHOOT IN

1714
01:10:33,760 --> 01:10:36,320
2017 AND THAT LIFTS THE MOONSHOT

1715
01:10:36,320 --> 01:10:40,080
AMOUNT OF THE YEAR TO

1716
01:10:40,080 --> 01:10:42,360
$216 MILLION AND OF THE FOUR

1717
01:10:42,360 --> 01:10:44,680
CONGRESS PROVIDED $150 MILLION

1718
01:10:44,680 --> 01:10:47,800
MUST BE SPENT ON COMPETING AND

1719
01:10:47,800 --> 01:10:50,520
CONTINUING GRANTS AND WE'LL

1720
01:10:50,520 --> 01:10:53,280
CHECK THAT BOX.

1721
01:10:53,280 --> 01:10:54,800
NIH GOT A $3 BILLION INCREASE

1722
01:10:54,800 --> 01:11:01,400
THAT IS A PLUS 6.5% AND THAT

1723
01:11:01,400 --> 01:11:02,720
TOTAL I AM INCLUDES A BILLION

1724
01:11:02,720 --> 01:11:09,600
AND A HALF FOR ARPA-H, FOCUS ON

1725
01:11:09,600 --> 01:11:14,000
THAT BECAUSE ARPA-H HAS A CANCER

1726
01:11:14,000 --> 01:11:19,480
FOCUS IN ADDITION TO A GLOBAL

1727
01:11:19,480 --> 01:11:20,880
HEALTH AND THAT IS A HALF A

1728
01:11:20,880 --> 01:11:22,040
BILLION DOLLARS INCREASE OVER

1729
01:11:22,040 --> 01:11:23,040
THE PRIOR YEAR.

1730
01:11:23,040 --> 01:11:25,880
AND THERE AT THE BOTTOM, YOU SEE

1731
01:11:25,880 --> 01:11:29,680
KIND OF THE TASK THAT ARPA-H HAS

1732
01:11:29,680 --> 01:11:33,360
GIVEN IN A BROAD CO CONTEXT TO

1733
01:11:33,360 --> 01:11:34,440
ADVANCE HEALTH AND HEALTH

1734
01:11:34,440 --> 01:11:35,440
RESEARCH.

1735
01:11:35,440 --> 01:11:40,320
SO, NEXT SLIDE, PLEASE.

1736
01:11:40,320 --> 01:11:42,280
THIS IS A CLASSIC TABLE WE USE

1737
01:11:42,280 --> 01:11:43,440
YEAR IN AND YEAR OUT.

1738
01:11:43,440 --> 01:11:45,560
THE FIRST THING I SEE HERE IS

1739
01:11:45,560 --> 01:11:50,840
THAT 30 IN THE 2017 COLUMN.

1740
01:11:50,840 --> 01:11:52,120
I MUST HAVE DONE SOMETHING WHEN

1741
01:11:52,120 --> 01:11:53,920
I WAS SAVING IT THAT'S A 300 AND

1742
01:11:53,920 --> 01:11:55,840
JOY I'LL CORRECT THAT FOR THE

1743
01:11:55,840 --> 01:11:59,080
ONE WE DISPLAY FOR THE RECORD.

1744
01:11:59,080 --> 01:12:02,520
IS SO, SMALLER OR THERE BUT THE

1745
01:12:02,520 --> 01:12:06,560
ORANGE BOXES SHOW THE SEVEN

1746
01:12:06,560 --> 01:12:08,480
SUCCESS I HAVE YEARS OF CURES

1747
01:12:08,480 --> 01:12:09,360
ACT FUNDING.

1748
01:12:09,360 --> 01:12:16,320
START NORTH 2017 AND 2023 IS THE

1749
01:12:16,320 --> 01:12:16,920
FINAL YEAR.

1750
01:12:16,920 --> 01:12:21,760
WE CALL THAT A CLIFF AND WITHOUT

1751
01:12:21,760 --> 01:12:24,440
SOME CONCRETE ACTION, THIS

1752
01:12:24,440 --> 01:12:29,280
$216 MILLION YOU SEE THERE WILL

1753
01:12:29,280 --> 01:12:34,360
DISAPPEAR AND THAT'S ABOUT 3% OF

1754
01:12:34,360 --> 01:12:36,080
OUR BUDGET AND WE'RE KEEPING A

1755
01:12:36,080 --> 01:12:37,080
CLOSE EYE ON THAT AND THE

1756
01:12:37,080 --> 01:12:40,520
ADMINISTRATION IS AS WELL.

1757
01:12:40,520 --> 01:12:44,560
IN THE GREEN BOX WE HAVE THE

1758
01:12:44,560 --> 01:12:46,880
$50 MILLION FOR CHILDHOOD CANCER

1759
01:12:46,880 --> 01:12:48,560
INITIATIVES THAT IS A 10-YEAR

1760
01:12:48,560 --> 01:12:50,240
INITIATIVE AND WE'RE NOT QUITE

1761
01:12:50,240 --> 01:12:51,920
HALFWAY THROUGH THAT WITH THE

1762
01:12:51,920 --> 01:12:53,400
MONEY WE RECEIVED THIS YEAR.

1763
01:12:53,400 --> 01:12:55,800
SO THOSE ARE TWO OF A MORE

1764
01:12:55,800 --> 01:13:01,000
MODEST COMPONENTS IN THE LARGER

1765
01:13:01,000 --> 01:13:04,240
INCREASE OR BUDGET AMOUNT THE

1766
01:13:04,240 --> 01:13:10,080
$7 BILLION MAKING UP A TOTAL OF

1767
01:13:10,080 --> 01:13:11,160
$7.3 BILLION FOR THE YEAR THAT

1768
01:13:11,160 --> 01:13:14,960
WE'VE ENTERED, YEAR IN THE PAST.

1769
01:13:14,960 --> 01:13:17,920
WE ENTERED IT IN OCTOBER 1 BUT

1770
01:13:17,920 --> 01:13:20,160
THE APPROPRIATION CAME TO US AT

1771
01:13:20,160 --> 01:13:21,440
THE END OF DECEMBER.

1772
01:13:21,440 --> 01:13:23,760
NEXT SLIDE, PLEASE.

1773
01:13:23,760 --> 01:13:26,280
SO IN THIS SLIDE, I'M DISPLAYING

1774
01:13:26,280 --> 01:13:29,000
THE TABLE THAT APPEARED IN Dr.

1775
01:13:29,000 --> 01:13:31,360
BERTAGNOLLI'S FEBRUARY 

1776
01:13:31,360 --> 01:13:36,120
FEBRUARY 6th POST IN NCI'S

1777
01:13:36,120 --> 01:13:37,360
BOTTOM LINE BLOG.

1778
01:13:37,360 --> 01:13:40,280
IT SHOWS FUNDING POLICIES FOR

1779
01:13:40,280 --> 01:13:42,200
2023 AND COMPARED TO LAST FISCAL

1780
01:13:42,200 --> 01:13:44,200
YEAR WHAT YOU ARE SEEING IS NCI

1781
01:13:44,200 --> 01:13:46,840
RAISING THE PAYLINE FOR RO1 AND

1782
01:13:46,840 --> 01:13:52,800
THE ESIRO1s BY 1% TILE EACH

1783
01:13:52,800 --> 01:13:58,680
FROM 11% TO 12% FOR RO1 AND 16%

1784
01:13:58,680 --> 01:14:06,400
TO 17% FOR ES I-RO1s, WE

1785
01:14:06,400 --> 01:14:08,920
EXPECT TO ISSUE 100 ADDITIONAL

1786
01:14:08,920 --> 01:14:13,040
RO OR ESI AWARDS COMPARED TO

1787
01:14:13,040 --> 01:14:14,280
LAST YEAR.

1788
01:14:14,280 --> 01:14:16,080
AND THESE PAYLINE INCREASES ARE

1789
01:14:16,080 --> 01:14:18,400
POSSIBLE BECAUSE OF THE GENEROUS

1790
01:14:18,400 --> 01:14:21,600
INCREASE WE RECEIVED FROM

1791
01:14:21,600 --> 01:14:22,360
CONGRESS.

1792
01:14:22,360 --> 01:14:24,200
THIS YEAR, JUST LIKE IN THE

1793
01:14:24,200 --> 01:14:26,320
PRIOR YEAR, THE R21 EXPLORATORY

1794
01:14:26,320 --> 01:14:30,160
GRANTS WILL REMAIN AT 9%.

1795
01:14:30,160 --> 01:14:33,440
BUT TO ENSURE WE CAN MEET THESE

1796
01:14:33,440 --> 01:14:37,720
PAYLINE INCREASES, YOU KNOW, 100

1797
01:14:37,720 --> 01:14:38,600
ADDITIONAL GRANTS THAT ADDS UP

1798
01:14:38,600 --> 01:14:40,320
AND THERE ARE GRANT INCREASES IN

1799
01:14:40,320 --> 01:14:43,040
SOME OTHER CATEGORIES, NOT

1800
01:14:43,040 --> 01:14:44,960
DISPLAYED HERE, WE'VE HAD TO DO

1801
01:14:44,960 --> 01:14:47,960
JUST WHAT WE DID LAST YEAR, ONCE

1802
01:14:47,960 --> 01:14:50,480
AGAIN, FUND NON COMPETING AWARDS

1803
01:14:50,480 --> 01:14:54,440
AT THE THE 98%.

1804
01:14:54,440 --> 01:15:00,840
WITH IN TARGETED EXCEPTIONS YOU

1805
01:15:00,840 --> 01:15:05,600
SEE ON THE RIGHT HAND SIDE AND

1806
01:15:05,600 --> 01:15:07,600
NCI IS IS MAKING CUTS TO

1807
01:15:07,600 --> 01:15:12,240
INVERNAL BUDGETS AND WE'RE OWE

1808
01:15:12,240 --> 01:15:14,400
POTION A 2% OFFICES AND CENTERS

1809
01:15:14,400 --> 01:15:18,200
AND THIS ALLOWS US TO PRIORITIZE

1810
01:15:18,200 --> 01:15:22,120
FUNDING FOR ROS AND ESI

1811
01:15:22,120 --> 01:15:25,760
COMPETING AWARDS AND YOU HAVE A

1812
01:15:25,760 --> 01:15:29,880
LINK AT BOTTOM OF THE PAGE O THO

1813
01:15:29,880 --> 01:15:31,440
THE GRANT FUNDING POLICIES WHERE

1814
01:15:31,440 --> 01:15:34,960
THERE'S MORE DETAIL AVAILABLE TO

1815
01:15:34,960 --> 01:15:37,360
THE PUBLIC.

1816
01:15:37,360 --> 01:15:37,960
SO, THIS IS A FLASH BACK.

1817
01:15:37,960 --> 01:15:40,520
I'M SHOWING YOU HERE A SLIDE I

1818
01:15:40,520 --> 01:15:41,480
PRESENTED LAST YEAR.

1819
01:15:41,480 --> 01:15:43,680
IT'S NOT EXACTLY THE SAME SLIDE.

1820
01:15:43,680 --> 01:15:45,640
IN JUNE I SHOWED THE RED AND THE

1821
01:15:45,640 --> 01:15:56,160
GREEN AND THE BLUE COMPONENTS

1822
01:15:56,880 --> 01:16:00,200
AND 27 INCREASE IN '21 AND

1823
01:16:00,200 --> 01:16:00,880
'22 WAS $39 MILLION INCREASE AND

1824
01:16:00,880 --> 01:16:04,440
I ADDED IN GOLD THE 2023 PIECE

1825
01:16:04,440 --> 01:16:07,560
WHICH IS IS $28 MILLION SO YOU

1826
01:16:07,560 --> 01:16:10,840
SEE ACROSS THESE YEARS

1827
01:16:10,840 --> 01:16:13,080
$169 MILLION IN TOTAL INCREASE

1828
01:16:13,080 --> 01:16:17,120
FOR NOT COMPETING GRANTS.

1829
01:16:17,120 --> 01:16:21,720
AND NOW LET'S MOVE TO THE NEXT

1830
01:16:21,720 --> 01:16:25,720
SLIDE OF AND THIS IS A COMPLEX

1831
01:16:25,720 --> 01:16:27,240
DISPLAY AND IT'S NEARLY DESIGNED

1832
01:16:27,240 --> 01:16:29,960
TO SHOW THE MULTI YEAR

1833
01:16:29,960 --> 01:16:31,320
CONSEQUENCES OF ALL THESE

1834
01:16:31,320 --> 01:16:33,000
COMMITMENT TO GRANTS.

1835
01:16:33,000 --> 01:16:35,200
AND HOW THEY COMPOUND ACROSS THE

1836
01:16:35,200 --> 01:16:35,920
YEARS.

1837
01:16:35,920 --> 01:16:37,680
AND HERE YOU SEE LOOKING FROM

1838
01:16:37,680 --> 01:16:42,680
LEFT TO RIGHT, $75 MILLION WE

1839
01:16:42,680 --> 01:16:45,360
START INSIDE 2020 WILL OF COURSE

1840
01:16:45,360 --> 01:16:47,000
FOR FIVE SUCCESS I HAVE YEARS IF

1841
01:16:47,000 --> 01:16:50,520
IT'S AN RO1 OR IT WOULD BE SEVEN

1842
01:16:50,520 --> 01:16:54,600
YEARS IF IT WAS AN R-37 MERIT

1843
01:16:54,600 --> 01:16:56,920
AWARD FOR ESI WE HAVE THOSE

1844
01:16:56,920 --> 01:17:00,760
COSTS NOW I WANT TO BE CLEAR NOT

1845
01:17:00,760 --> 01:17:06,840
# HUNDRE100% OF THE $73 MILLIONE

1846
01:17:06,840 --> 01:17:08,480
PAYLINE AND THAT'S THE MOST

1847
01:17:08,480 --> 01:17:11,600
PROMINENT ONE BUT THERE ARE

1848
01:17:11,600 --> 01:17:13,760
OTHER SMALLER DRIVERS IN THERE

1849
01:17:13,760 --> 01:17:15,480
AS WELL AND THEY ADD TO THE

1850
01:17:15,480 --> 01:17:19,400
TOTAL, YOU ARE SEEING THE TOTAL

1851
01:17:19,400 --> 01:17:20,520
INCREASE AND THEM YOU GET OUT OF

1852
01:17:20,520 --> 01:17:22,640
THE GREEN AND WE ADD THOSE YEARS

1853
01:17:22,640 --> 01:17:24,320
AND BLUE AND WE ADD THOSE YEARS

1854
01:17:24,320 --> 01:17:25,960
AND NOW WE'RE STARTING FIVE OR

1855
01:17:25,960 --> 01:17:29,040
IN SOME CASES SEVEN YEARS OF

1856
01:17:29,040 --> 01:17:31,760
ADDITIONAL COMMITMENT AND YOU

1857
01:17:31,760 --> 01:17:33,760
CAN SEE IF YOU LOOK FROM TOP TO

1858
01:17:33,760 --> 01:17:36,040
BOTTOM, YOU CAN SEE HOW THOSE

1859
01:17:36,040 --> 01:17:39,040
COSTS ADD UP AND COMPOUND ACROSS

1860
01:17:39,040 --> 01:17:40,760
THE YEARS.

1861
01:17:40,760 --> 01:17:45,360
AND THERE'S A COUPLE OTHER

1862
01:17:45,360 --> 01:17:46,240
FACTORS THAT ARE ALSO WORTH WILE

1863
01:17:46,240 --> 01:17:46,600
CONSIDERING.

1864
01:17:46,600 --> 01:17:48,400
EVERY YEAR WE DRIVE TO MAKE MORE

1865
01:17:48,400 --> 01:17:50,400
AWARDS.

1866
01:17:50,400 --> 01:17:54,200
I MENTIONE MENTION 100 ADDITIONS

1867
01:17:54,200 --> 01:17:59,040
FOR ESI AND RO1 AWARDS AND SO

1868
01:17:59,040 --> 01:18:01,760
THAT WHAT WE HAVE THE LAST YEAR

1869
01:18:01,760 --> 01:18:05,480
OF AN EXPIRING GRANT COHORT,

1870
01:18:05,480 --> 01:18:07,160
THOSE DOLLARS AREN'T SUFFICIENT

1871
01:18:07,160 --> 01:18:09,240
TO FUND THE NEW LARGER COHORT.

1872
01:18:09,240 --> 01:18:10,880
AND THEN YOU CONSIDER INFLATION

1873
01:18:10,880 --> 01:18:14,440
AS WELL.

1874
01:18:14,440 --> 01:18:15,080
WHICH ALSO DEFLEETS THE BUYING

1875
01:18:15,080 --> 01:18:20,240
POWER SO THEN YOU ARE A PICTURE

1876
01:18:20,240 --> 01:18:22,520
OF THE COST STRUCTURE OF MAKING

1877
01:18:22,520 --> 01:18:25,440
A ONE-YEAR INITIAL COMMITMENT ON

1878
01:18:25,440 --> 01:18:27,800
COMPETING AND HOW IT PLAYS OUT

1879
01:18:27,800 --> 01:18:31,720
INTO NON COMPETING AWARDS AND

1880
01:18:31,720 --> 01:18:33,360
LET'S MOVE TO THE NEXT SLIDE,

1881
01:18:33,360 --> 01:18:33,800
PLEASE.

1882
01:18:33,800 --> 01:18:36,080
AND I JUST WANT TO OFFER THIS AS

1883
01:18:36,080 --> 01:18:39,560
A ALTERNATIVE VIEW, OUR FRIENDS

1884
01:18:39,560 --> 01:18:42,800
IN OEFIA OFFICE DEVELOPED THIS

1885
01:18:42,800 --> 01:18:44,240
AND I'M NOT GOING TO RUN THROUGH

1886
01:18:44,240 --> 01:18:46,920
IT AGAIN.

1887
01:18:46,920 --> 01:18:48,120
IT'S MERELY ANOTHER ILLUSTRATION

1888
01:18:48,120 --> 01:18:51,320
OF WHAT HAPPENS ACROSS THE YEARS

1889
01:18:51,320 --> 01:18:53,960
FOR WHEN WE MAKE A COMMITMENT A

1890
01:18:53,960 --> 01:18:55,760
COMPETING YEAR WHAT HAPPENS AND

1891
01:18:55,760 --> 01:18:59,240
THE COST AND HOW THEY DO

1892
01:18:59,240 --> 01:18:59,520
COMPOUND.

1893
01:18:59,520 --> 01:19:00,880
THIS IS ALL WORTH WHILE DOLLARS

1894
01:19:00,880 --> 01:19:05,400
WE'RE PUTTING OUT THERE FOR

1895
01:19:05,400 --> 01:19:06,320
SIGNIFICANT RESEARCH BUT THERE'S

1896
01:19:06,320 --> 01:19:11,360
A COST STRUCTURE AND THAT WE

1897
01:19:11,360 --> 01:19:12,040
FACE.

1898
01:19:12,040 --> 01:19:15,960
NEXT SLIDE, PLEASE.

1899
01:19:15,960 --> 01:19:17,760
AND NOW TURNING TO '24, YOU ARE

1900
01:19:17,760 --> 01:19:21,920
SEEING CONTACT FROM A MEMO CO

1901
01:19:21,920 --> 01:19:24,920
AUTHORED BY OMB DIRECTOR AND

1902
01:19:24,920 --> 01:19:28,520
NATIONAL ECONOMIC COUNCIL

1903
01:19:28,520 --> 01:19:31,280
ADVISER AND THE MEMO RELATED TO

1904
01:19:31,280 --> 01:19:32,920
A DRAMA OVER THE DEBT CEILING.

1905
01:19:32,920 --> 01:19:34,760
IT WAS A WHITE HOUSE SAYING

1906
01:19:34,760 --> 01:19:35,720
WE'RE SHOWING THE AMERICAN

1907
01:19:35,720 --> 01:19:38,000
PUBLIC OUR BUDGET SO,

1908
01:19:38,000 --> 01:19:39,520
REPUBLICANS CAN DO THE SAME BUT

1909
01:19:39,520 --> 01:19:41,040
I'M NOT WAITING INTO THAT AND

1910
01:19:41,040 --> 01:19:42,680
I'M TRYING TO FIND OUT THAT HERE

1911
01:19:42,680 --> 01:19:47,200
WE ARE ON PAGE ONE OF THE MEMO,

1912
01:19:47,200 --> 01:19:48,640
WE'RE TOLD THAT PRESIDENT JOE

1913
01:19:48,640 --> 01:19:51,360
BIDEN WILL RELEASE A BUDGET ON

1914
01:19:51,360 --> 01:19:52,880
THE NINTH OF MARCH AND AT THE

1915
01:19:52,880 --> 01:19:55,360
SAME TIME, WE'LL HAVE A DISPLAY

1916
01:19:55,360 --> 01:19:57,440
OF WHAT THE FINAL GRANT COUNT IS

1917
01:19:57,440 --> 01:20:01,160
IS FOR NCI SO THAT'S A DATE WE

1918
01:20:01,160 --> 01:20:02,520
CAN WATCH.

1919
01:20:02,520 --> 01:20:04,280
YOU CAN CALL THAT CLEARLY A

1920
01:20:04,280 --> 01:20:06,400
KNOWN UNKNOWN O WE DON'T KNOW

1921
01:20:06,400 --> 01:20:08,160
WHAT THAT BUDGET AMOUNT IS BUT

1922
01:20:08,160 --> 01:20:10,080
WE KNOW IT'S COMING AND IT'S

1923
01:20:10,080 --> 01:20:11,880
RELATIVELY AROUND THE CORNER

1924
01:20:11,880 --> 01:20:14,760
MONTH FROM TODAY.

1925
01:20:14,760 --> 01:20:17,080
SO, ALL I WANT TO EMPHASIZE IS

1926
01:20:17,080 --> 01:20:18,600
THE ENVIRONMENT AND CONGRESS AND

1927
01:20:18,600 --> 01:20:24,520
A NEW CONGRESS WE HAVE A DIVIDED

1928
01:20:24,520 --> 01:20:25,080
CONGRESS.

1929
01:20:25,080 --> 01:20:28,760
OF COURSE, THE DEMOCRATIC PAR

1930
01:20:28,760 --> 01:20:33,520
PARTY HAS THE WHITE HOUSE WITH

1931
01:20:33,520 --> 01:20:35,360
PRESIDENT BIDEN BUT WE HAD A

1932
01:20:35,360 --> 01:20:37,320
DEBT CEILING CRISIS IN THE SAME

1933
01:20:37,320 --> 01:20:43,080
ERA A DECADE AGO THAT WAS A

1934
01:20:43,080 --> 01:20:44,520
STORMY PERIOD AND YOU HAVE TO

1935
01:20:44,520 --> 01:20:46,640
ASK YOURSELF WHETHER OF HISTORY

1936
01:20:46,640 --> 01:20:50,280
MAY NOT REPEAT ITSELF BUT THE

1937
01:20:50,280 --> 01:20:51,360
SIMILARITIES MAKE YOU WONDER

1938
01:20:51,360 --> 01:20:56,600
ABOUT THE POSSIBILITY OF DEJA

1939
01:20:56,600 --> 01:20:57,000
VU.

1940
01:20:57,000 --> 01:21:01,200
TO BRING THE DISCUSSION TO A

1941
01:21:01,200 --> 01:21:03,520
CLOSE, I WANT TO SPOTLIGHT HOW

1942
01:21:03,520 --> 01:21:04,680
MUCH CANCER DISCOVERY AND THE

1943
01:21:04,680 --> 01:21:07,240
NEEDS OF CANCER PATIENTS ARE

1944
01:21:07,240 --> 01:21:08,480
PRIORITIES FOR PRESIDENT BIDEN

1945
01:21:08,480 --> 01:21:15,240
AND FIRST LADY JOE BIDEN.

1946
01:21:15,240 --> 01:21:17,280
THEY WILL EMPHASIZE ADDRESSES TO

1947
01:21:17,280 --> 01:21:18,560
THE NATION BY PRESIDENT JOE

1948
01:21:18,560 --> 01:21:23,160
BIDEN AND 2021, IN HIS FIRST

1949
01:21:23,160 --> 01:21:24,440
ADDRESS TO THE JOINT SESSION OF

1950
01:21:24,440 --> 01:21:25,640
CONGRESS WE LEARNED CANCER WOULD

1951
01:21:25,640 --> 01:21:27,120
BE A PRIORITY FOCUS OF THE JOE

1952
01:21:27,120 --> 01:21:31,480
BIDEN ADMINISTRATION AND WAS AN

1953
01:21:31,480 --> 01:21:32,960
EX OWE OF WHAT HE SAID

1954
01:21:32,960 --> 01:21:34,720
THROUGHOUT THE CAMPAIGN AND I'VE

1955
01:21:34,720 --> 01:21:36,040
HIGHLIGHTED IN YELLOW SOME OF

1956
01:21:36,040 --> 01:21:41,440
THE KEY MESSA PASSAGES N-2022 TE

1957
01:21:41,440 --> 01:21:42,640
STATE OF THE UNION THE BOX ON

1958
01:21:42,640 --> 01:21:44,960
THE RIGHT, HE ANNOUNCE THE HIS

1959
01:21:44,960 --> 01:21:47,440
PLAN TO SUPER CHARGE THE CANCER

1960
01:21:47,440 --> 01:21:48,760
MOONSHOT SETTING THE CHALLENGE

1961
01:21:48,760 --> 01:21:51,040
FOR NCI AND ALL OF GOVERNMENT

1962
01:21:51,040 --> 01:21:53,560
FRANKLY TO CUT CANCER DEATH IN

1963
01:21:53,560 --> 01:21:58,240
HALF IN 25 YEARS.

1964
01:21:58,240 --> 01:22:00,040
THURSDAY NIGHT TWO DAYS AGO, WE

1965
01:22:00,040 --> 01:22:02,080
HEARD FROM THE PRESIDENT, AGAIN,

1966
01:22:02,080 --> 01:22:03,480
FOR THE THIRD TIME IN THREE

1967
01:22:03,480 --> 01:22:06,560
YEARS IN ADDRESS TO CONGRESS AND

1968
01:22:06,560 --> 01:22:11,120
THE NATION WE WITNESSED A BRIGHT

1969
01:22:11,120 --> 01:22:18,480
SPOTLIGHT ON EVIDENCE CA OF CAN.

1970
01:22:18,480 --> 01:22:20,600
HE HAD 13 TIMES REFERENCE TO CAP

1971
01:22:20,600 --> 01:22:20,880
SER.

1972
01:22:20,880 --> 01:22:22,600
MORE THAN HE REFERRED TO THE

1973
01:22:22,600 --> 01:22:26,840
ECONOMY AND INFRASTRUCTURE,

1974
01:22:26,840 --> 01:22:29,640
COVID-19, CHINA, AND EVEN MORE

1975
01:22:29,640 --> 01:22:31,240
TIMES THAN HE MENTIONED

1976
01:22:31,240 --> 01:22:41,680
REPUBLICANREPUBLICAN OR DEMOCRA.

1977
01:22:41,680 --> 01:22:45,960
RONALD REGULARONALD REAGAN STARG

1978
01:22:45,960 --> 01:22:47,160
HUMAN APP STORIES ABOUT CANCER.

1979
01:22:47,160 --> 01:22:48,440
THERE WERE FOUR OF THEM.

1980
01:22:48,440 --> 01:22:50,920
A FAMILY FROM NEW YORK WITH A

1981
01:22:50,920 --> 01:22:52,560
4-YEAR-OLD THAT SUFFERED FROM

1982
01:22:52,560 --> 01:22:56,200
KIDNEY CAP SER, A BREAST CANCER

1983
01:22:56,200 --> 01:22:57,280
SURVIVOR AND ARIZONA NURSE IN

1984
01:22:57,280 --> 01:22:59,400
THE FIRST CANCER CLINIC ON A

1985
01:22:59,400 --> 01:23:00,840
NATIVE AMERICAN RESERVATION AND

1986
01:23:00,840 --> 01:23:03,240
A HERO WHO ENDED A MASS SHOOTING

1987
01:23:03,240 --> 01:23:06,720
THAT HE HAD POSTPONED HIS

1988
01:23:06,720 --> 01:23:08,520
COLLEGE TO CARE FOR HIS MOM

1989
01:23:08,520 --> 01:23:10,240
DYING OF CANCER.

1990
01:23:10,240 --> 01:23:11,560
IT'S COMPELLING EVIDENCE OF THE

1991
01:23:11,560 --> 01:23:15,560
DIE DENBIDEN'S COMMITMENT TO CA 

1992
01:23:15,560 --> 01:23:17,440
AND THE WORK OF NCI AND IN THE

1993
01:23:17,440 --> 01:23:19,000
HOURS BEFORE THE STATE OF THE

1994
01:23:19,000 --> 01:23:20,840
UNION, THE WHITE HOUSE RELEASED

1995
01:23:20,840 --> 01:23:23,400
A FACT SHEET ON ITS AGENDA FOR

1996
01:23:23,400 --> 01:23:26,480
THE YEAR AHEAD AND THE FIRST

1997
01:23:26,480 --> 01:23:29,800
AGENDA TOPIC WAS CANCER.

1998
01:23:29,800 --> 01:23:31,680
I'LL POST OF THE LINK TO THAT

1999
01:23:31,680 --> 01:23:38,320
FACT SHEET IN THE CHAT.

2000
01:23:38,320 --> 01:23:40,000
IT INCLUDES TACKLING THE BIGGEST

2001
01:23:40,000 --> 01:23:41,880
SINGLE DRIVER OF CANCER DEATHS

2002
01:23:41,880 --> 01:23:44,320
WHICH IS SMOKING.

2003
01:23:44,320 --> 01:23:45,400
PROVIDING PATIENT NAVIGATION

2004
01:23:45,400 --> 01:23:46,760
SUPPORT FOR EVERY AMERICAN

2005
01:23:46,760 --> 01:23:49,120
FACING CANCER AND BRINGING

2006
01:23:49,120 --> 01:23:50,800
AMERICA'S CANCER RESEARCH SYSTEM

2007
01:23:50,800 --> 01:23:52,920
INTO THE 21st CENTURY AND THEN

2008
01:23:52,920 --> 01:23:55,120
JUST A MOMENT MORE FINALLY ON

2009
01:23:55,120 --> 01:23:57,400
THE THIRD POINT, IT DESERVES

2010
01:23:57,400 --> 01:23:59,080
MORE DISCUSSION BECAUSE WITH IT

2011
01:23:59,080 --> 01:24:00,680
THE ADMINISTRATION ANNOUNCED A

2012
01:24:00,680 --> 01:24:04,960
PLAN TO REFRESH, AS Dr. BARKER

2013
01:24:04,960 --> 01:24:06,200
MENTIONED THE NATIONAL CANCER

2014
01:24:06,200 --> 01:24:09,240
ACT AND PART OF HIS PLAN IS

2015
01:24:09,240 --> 01:24:10,760
ALSO, I WANT TO QUOTE, TO WORK

2016
01:24:10,760 --> 01:24:14,800
WITH CONGRESS TO LOCK IN THE

2017
01:24:14,800 --> 01:24:16,320
STRONG INVESTMENT AND CANCER

2018
01:24:16,320 --> 01:24:19,760
RESEARCH THAT WAS PASSED IN 2016

2019
01:24:19,760 --> 01:24:24,000
AS PART OF THE 20th CURES ACT

2020
01:24:24,000 --> 01:24:26,360
CANCER MOONSHOT WHICH EXPIRES

2021
01:24:26,360 --> 01:24:27,280
THIS YEAR.

2022
01:24:27,280 --> 01:24:29,760
AND THAT BRINGS US BACK TO THAT

2023
01:24:29,760 --> 01:24:33,600
BAR GRAPH AND THE CLIFF FOR

2024
01:24:33,600 --> 01:24:33,920
2023.

2025
01:24:33,920 --> 01:24:37,160
SO WE DON'T HAVE SPECIFICS BUT,

2026
01:24:37,160 --> 01:24:39,000
CLEARLY THERE'S AN OBJECTIVE

2027
01:24:39,000 --> 01:24:41,440
THAT HE HAS IN MIND AND THE

2028
01:24:41,440 --> 01:24:43,360
ADMINISTRATION HAS IN MIND TO

2029
01:24:43,360 --> 01:24:46,880
ADDRESS THAT AND CONTINUE CANCER

2030
01:24:46,880 --> 01:24:48,480
MOONSHOT FUND NORTH SOMEWAY OR

2031
01:24:48,480 --> 01:24:50,000
FORM AND WE'LL LEARN MORE ABOUT

2032
01:24:50,000 --> 01:24:56,360
THAT ON THE NINTH OF MARCH I'M

2033
01:24:56,360 --> 01:24:57,840
AT MY END.

2034
01:24:57,840 --> 01:24:59,640
AND I'LL TURN IT OVER TO

2035
01:24:59,640 --> 01:25:00,720
QUESTIONS OR MEAN YOU WANT TO

2036
01:25:00,720 --> 01:25:03,440
HEAR FROM DIANNE AND WE'LL HAVE

2037
01:25:03,440 --> 01:25:04,360
QUESTIONS COLLECTIVELY.

2038
01:25:04,360 --> 01:25:06,360
>>SO,  I THINK WE'LL TAKE
A

2039
01:25:06,360 --> 01:25:09,920
COUPLE QUESTIONS HERE IF THERE

2040
01:25:09,920 --> 01:25:10,480
ARE ANY.

2041
01:25:10,480 --> 01:25:12,720
I'LL ASK THE FIRST ONE.

2042
01:25:12,720 --> 01:25:14,640
LET ME JUST ASK THIS TO THE

2043
01:25:14,640 --> 01:25:15,880
POSITIVE WAY, I'M TRYING TO

2044
01:25:15,880 --> 01:25:18,000
THINK OF A POSITIVE WAY TO FRAME

2045
01:25:18,000 --> 01:25:18,440
THIS.

2046
01:25:18,440 --> 01:25:19,440
WE'VE TALKED IN THIS COMMITTEE

2047
01:25:19,440 --> 01:25:21,240
FOR THE LAST COUPLE OF YEARS

2048
01:25:21,240 --> 01:25:23,880
ABOUT THIS GOAL, WE HAD TO GET

2049
01:25:23,880 --> 01:25:28,920
THE PAYLINE TO 15% BY 2025.

2050
01:25:28,920 --> 01:25:30,320
I'M NOT GOING TO ASK YOU,

2051
01:25:30,320 --> 01:25:31,040
PATRICK, IF YOU THINK THAT'S

2052
01:25:31,040 --> 01:25:32,720
GOING TO HAPPEN BUT I'M GOING TO

2053
01:25:32,720 --> 01:25:34,840
ASK YOU WHAT YOU THINK IT WOULD

2054
01:25:34,840 --> 01:25:42,080
TAKE TO MAKE THAT HAPPEN?

2055
01:25:42,080 --> 01:25:43,360
>>IT WILL PROBABLY TAKE
ANOTHER

2056
01:25:43,360 --> 01:25:45,000
MOON SHOOT COMMITMENT AND IT

2057
01:25:45,000 --> 01:25:45,840
TAKES DOLLARS.

2058
01:25:45,840 --> 01:25:49,880
THERE'S NO ESCAPING THAT.

2059
01:25:49,880 --> 01:25:52,120
I'LL SAY HOPEFULLY, WE DON'T GET

2060
01:25:52,120 --> 01:25:53,920
TO PRINT THE DOLLARS WE GET TO

2061
01:25:53,920 --> 01:25:55,240
RECEIVE THEM FROM CONGRESS.

2062
01:25:55,240 --> 01:25:57,720
IF THAT'S WHAT IT TAKES AND --

2063
01:25:57,720 --> 01:26:00,920
YOU KNOW, WE WILL KNOW MORE IN A

2064
01:26:00,920 --> 01:26:03,680
MONTH WHEN WE HAVE THAT BUDGET

2065
01:26:03,680 --> 01:26:05,560
ANNOUNCEMENT FOR ALL OF

2066
01:26:05,560 --> 01:26:06,680
GOVERNMENT, INCLUDING NCI FROM

2067
01:26:06,680 --> 01:26:08,920
THE WHITE HOUSE.

2068
01:26:08,920 --> 01:26:10,880
>>I POINT THIS OUT
BECAUSE IT'S

2069
01:26:10,880 --> 01:26:12,160
ONE OF THE MOST CRITICAL POINTS

2070
01:26:12,160 --> 01:26:14,040
I THINK IN THE NCI.

2071
01:26:14,040 --> 01:26:15,360
I'VE SEEN FOR A VERY LONG TIME

2072
01:26:15,360 --> 01:26:18,360
IN TERMS OF A BUDGET THAT IS

2073
01:26:18,360 --> 01:26:22,880
NECESSARY, NOT TO MOVE BACKWARDS

2074
01:26:22,880 --> 01:26:24,920
AND I'M HOPING THAT IS GOING TO

2075
01:26:24,920 --> 01:26:27,520
BE POSITIVE NEWS BECAUSE YOU

2076
01:26:27,520 --> 01:26:29,840
KNOW, WE REALLY DO HAVE OTHER

2077
01:26:29,840 --> 01:26:31,080
ISSUES TO DEAL WITH HERE OTHER

2078
01:26:31,080 --> 01:26:32,960
THAN JUST FUNDING THE RESEARCH

2079
01:26:32,960 --> 01:26:34,240
GRANTS THAT WE FUND.

2080
01:26:34,240 --> 01:26:35,720
YOU MENTIONED INFRASTRUCTURE FOR

2081
01:26:35,720 --> 01:26:36,120
EXAMPLE.

2082
01:26:36,120 --> 01:26:37,520
I'D LIKE TO COME BACK TO THAT

2083
01:26:37,520 --> 01:26:38,920
WITH A COMMITTEE BECAUSE I THINK

2084
01:26:38,920 --> 01:26:40,400
IT'S A KEY ISSUE.

2085
01:26:40,400 --> 01:26:44,440
LET'S SEE IF THIS ARE OTHER

2086
01:26:44,440 --> 01:26:54,640
QUESTIONS.

2087
01:26:56,160 --> 01:26:57,840
SEEING NONE, EVERYONE IS HAPPY

2088
01:26:57,840 --> 01:26:58,920
WITH THE BUDGET.

2089
01:26:58,920 --> 01:27:01,600
LET ME ASK ANOTHER QUESTION AND

2090
01:27:01,600 --> 01:27:03,480
I'M ASKING YOU TO THINK WITH US

2091
01:27:03,480 --> 01:27:06,200
A LITTLE BIT ABOUT THIS BUT YOU

2092
01:27:06,200 --> 01:27:10,520
KNOW, I'M FAMILIAR WITH THE

2093
01:27:10,520 --> 01:27:15,840
BIOMEDICAL PRICE EVERYBODY

2094
01:27:15,840 --> 01:27:17,320
DOESN'T PAY ANY ATTENTION TO IT

2095
01:27:17,320 --> 01:27:19,160
IF YOU LIVE IN THE ACADEMIA YOU

2096
01:27:19,160 --> 01:27:22,880
SHOULD KNOW ABOUT THIS AND SO,

2097
01:27:22,880 --> 01:27:27,200
WHERE ARE WE THOUGH IN TERMS OF

2098
01:27:27,200 --> 01:27:28,040
APPLYING REALISTIC INFLATION

2099
01:27:28,040 --> 01:27:32,280
NUMBERS TO OUR GRANTS AND WHAT

2100
01:27:32,280 --> 01:27:33,280
I'M ASKING WHAT'S IS OUR

2101
01:27:33,280 --> 01:27:36,520
SPENDING POWER IN THAT BUDGET

2102
01:27:36,520 --> 01:27:43,280
THINKING ABOUT REAL DOLLARS

2103
01:27:43,280 --> 01:27:49,560
VERSUS ARE WE DOING WELL IN THAT

2104
01:27:49,560 --> 01:27:52,960
REGARD OR HOW DO YOU THINK ABOUT

2105
01:27:52,960 --> 01:27:56,440
THE PURCHASING POWER WITHIN THAT

2106
01:27:56,440 --> 01:27:56,880
BUDGET?

2107
01:27:56,880 --> 01:28:02,440
>>SO ACROSS THE YEARS, WE
HAVE

2108
01:28:02,440 --> 01:28:04,840
HAD A 40% INCREASE IN OUR BUDGET

2109
01:28:04,840 --> 01:28:08,280
AND SO THAT IS AHEAD OF

2110
01:28:08,280 --> 01:28:12,160
INFLATION AND AHEAD OF THE

2111
01:28:12,160 --> 01:28:19,760
BIOMEDICAL PRICING AND SO WORE

2112
01:28:19,760 --> 01:28:21,400
INTO SOME CHALLENGING INFLATION

2113
01:28:21,400 --> 01:28:24,880
YEARS AND IN A YEAR OR TWO, WITH

2114
01:28:24,880 --> 01:28:30,520
INFLATION, A LOT CAN HAPPEN TO

2115
01:28:30,520 --> 01:28:31,400
EFFECT YOUR PURCHASING POWER.

2116
01:28:31,400 --> 01:28:35,840
WE'VE BEEN BLESSED BY LOW

2117
01:28:35,840 --> 01:28:37,840
INFLATION BUT WE KNOW INFLATION

2118
01:28:37,840 --> 01:28:38,840
IS COOKING UP AND HOW LONG IT

2119
01:28:38,840 --> 01:28:42,880
WILL SUSTAIN IS A QUESTION SO

2120
01:28:42,880 --> 01:28:44,800
IT'S A IMPORTANT QUESTION TO ASK

2121
01:28:44,800 --> 01:28:48,240
AND ONE TO STAY ON TOP OF

2122
01:28:48,240 --> 01:28:49,880
BECAUSE AN INCREASE THAT SOUNDS

2123
01:28:49,880 --> 01:28:53,280
GOOD MAY BE JUST BEATEN LARGELY

2124
01:28:53,280 --> 01:28:56,520
UP BY THE DRIP, DRIP, DRIP OF

2125
01:28:56,520 --> 01:28:57,080
INFLATION.

2126
01:28:57,080 --> 01:28:59,000
>>LAST YEAR, OBVIOUSLY --
I

2127
01:28:59,000 --> 01:29:00,400
WOULD HAVE POST RIGHT NOW INTO

2128
01:29:00,400 --> 01:29:02,040
THE CHAT THAT LINK I PROMISE,

2129
01:29:02,040 --> 01:29:03,200
SORRY.

2130
01:29:03,200 --> 01:29:03,800
I DIGRESS TODAY THAT.

2131
01:29:03,800 --> 01:29:04,160
>>THANK YOU.

2132
01:29:04,160 --> 01:29:05,600
>>THANK YOU, PATRICK.

2133
01:29:05,600 --> 01:29:07,440
I POINT THAT OUT BECAUSE, YOU

2134
01:29:07,440 --> 01:29:08,880
KNOW, LAST YEAR'S INFLATION

2135
01:29:08,880 --> 01:29:17,720
NUMBERS WEREN'T GOOD AND IF YOU

2136
01:29:17,720 --> 01:29:19,760
LOOK AT THE BIOTECH INDUSTRY,

2137
01:29:19,760 --> 01:29:23,400
THE FARM INDUSTRY AND THE TECH

2138
01:29:23,400 --> 01:29:26,120
INDUSTRY RIGHT NOW EVEN IF

2139
01:29:26,120 --> 01:29:32,640
HEALTHCARE SHARE CUTTING STAFFED

2140
01:29:32,640 --> 01:29:37,800
AND ALL THE DISCOVERY WE MAKE

2141
01:29:37,800 --> 01:29:44,800
DEPEND ON WE SEE A HUGE PULL

2142
01:29:44,800 --> 01:29:52,880
BACK IN ALL THOSE SECTORS AND

2143
01:29:52,880 --> 01:29:54,920
THE BIOTECHNOLOGY INDUSTRY HAS

2144
01:29:54,920 --> 01:29:56,120
BEEN DECIMATED IN THE LAST FEW

2145
01:29:56,120 --> 01:29:57,400
YEARS SO IT'S SMOG THINK ABOUT

2146
01:29:57,400 --> 01:30:02,160
IN TERMS OF HOW OUR -- HOW WE

2147
01:30:02,160 --> 01:30:08,080
CAN SPEND OUR MONEY AND WHERE

2148
01:30:08,080 --> 01:30:11,200
ARPA-H CAN HELP AND WE CAN GET

2149
01:30:11,200 --> 01:30:11,960
HELP ON SCALE AND THESE STICKY

2150
01:30:11,960 --> 01:30:16,000
PROBLEMS WE HAVE IN THAT REGARD

2151
01:30:16,000 --> 01:30:20,200
SO WE'LL MOVE ON AND THANK YOU

2152
01:30:20,200 --> 01:30:21,280
VERY MUCH ON WE HALF OF OUR

2153
01:30:21,280 --> 01:30:22,320
SUBCOMMITTEE AND IT'S A PLEASURE

2154
01:30:22,320 --> 01:30:27,200
TO WORK WITH YOU.

2155
01:30:27,200 --> 01:30:30,480
I MENTIONED OUR -- I ASKED FOR

2156
01:30:30,480 --> 01:30:31,680
THIS PRESENTATION BECAUSE EVERY

2157
01:30:31,680 --> 01:30:36,600
YEAR WE HAVE LOOKED AT OUR

2158
01:30:36,600 --> 01:30:40,680
BUDGET FOR WHAT WOULD IT TAKE TO

2159
01:30:40,680 --> 01:30:42,120
OPTIMIZE OUR CANCER RESEARCH IN

2160
01:30:42,120 --> 01:30:47,040
ANY GIVEN YEAR AND FROM 1971

2161
01:30:47,040 --> 01:30:48,760
WHEN PRESIDENT NIXON SAID

2162
01:30:48,760 --> 01:30:50,240
ESSENTIALLY, I WANT TO GO -- I

2163
01:30:50,240 --> 01:30:52,440
WANT TO GO ON RECORD AS SAYING,

2164
01:30:52,440 --> 01:30:54,480
I WANT TO KNOW WHAT IT'S GOING

2165
01:30:54,480 --> 01:30:56,560
TO TAKE TO MAKE THIS HAPPEN AND

2166
01:30:56,560 --> 01:30:58,640
I WANT TO KNOW THE BUDGET AND I

2167
01:30:58,640 --> 01:31:00,320
CAN GO TO CONGRESS WITH THAT AND

2168
01:31:00,320 --> 01:31:03,600
HE WAS TALKING TO PEOPLE THEN

2169
01:31:03,600 --> 01:31:07,520
LIKE TED KENNEDY AND PAUL PAUL

2170
01:31:07,520 --> 01:31:09,400
RODGERS AND PEOPLE IN THIS REAL

2171
01:31:09,400 --> 01:31:10,480
MOVEMENT FOR WHAT WAS THE

2172
01:31:10,480 --> 01:31:15,280
NATIONAL CANCER ACT AND SO HE

2173
01:31:15,280 --> 01:31:17,200
DEVELOPED SOMETHING CALLED THE

2174
01:31:17,200 --> 01:31:20,920
IDEA OF THE BYPASS BUDGET WHICH

2175
01:31:20,920 --> 01:31:23,520
WAS REAL FOR NCI IT'S A HUGE

2176
01:31:23,520 --> 01:31:25,240
NUMBER, EVERY SINGLE YEAR TO SIT

2177
01:31:25,240 --> 01:31:26,880
DOWN AND FIGURE OUT THIS IS WHAT

2178
01:31:26,880 --> 01:31:30,760
WE THINK WOULD REALLY OPTIMIZE

2179
01:31:30,760 --> 01:31:32,120
PROGRESS IN CAP SER RESEARCH AND

2180
01:31:32,120 --> 01:31:36,560
THIS IS WHAT IT COSTS.

2181
01:31:36,560 --> 01:31:38,000
UNFORTUNATELY, NOT EVEN THAT

2182
01:31:38,000 --> 01:31:39,520
MANY DECADES LATER, THAT BUDGET

2183
01:31:39,520 --> 01:31:41,360
YOU KNOW, DIDN'T ANY LONGER FIND

2184
01:31:41,360 --> 01:31:43,760
ITS WAY INTO THE PRESIDENT'S

2185
01:31:43,760 --> 01:31:45,520
OFFICE AND WE HAVEN'T HAD THAT

2186
01:31:45,520 --> 01:31:47,400
BUDGET FUNDED EVER SINCE I'VE

2187
01:31:47,400 --> 01:31:57,640
BEEN AROUND AND SO IT'S A

2188
01:31:57,640 --> 01:31:58,480
PLAINTIFF AND TO LOOK AT

2189
01:31:58,480 --> 01:31:59,240
INFRASTRUCTURE AND TO LOOK AT

2190
01:31:59,240 --> 01:32:00,920
THE WORKFORCE AND LOOK AT

2191
01:32:00,920 --> 01:32:02,480
EVERYTHING AND SEE WHERE DO WE

2192
01:32:02,480 --> 01:32:03,880
NEED TO SPEND OUR MONEY AND HOW

2193
01:32:03,880 --> 01:32:06,240
CAN WE REALLY MOVE THIS WHOLE

2194
01:32:06,240 --> 01:32:10,520
FIELD FORWARD AND SO, DIANNE HAS

2195
01:32:10,520 --> 01:32:15,160
THE HONOR OF DOING THAT AND THEY

2196
01:32:15,160 --> 01:32:16,320
KNOW WHEN I WAS THERE IT'S A LOT

2197
01:32:16,320 --> 01:32:17,640
OF WORK FOR A LOT OF PEOPLE AND

2198
01:32:17,640 --> 01:32:21,520
SHE'S OUR DIRECTOR OF CRS AND

2199
01:32:21,520 --> 01:32:23,600
SHE WILL TELL US ABOUT THIS

2200
01:32:23,600 --> 01:32:25,800
YEAR'S PLANNING BUDGET FOR THE

2201
01:32:25,800 --> 01:32:27,800
NCI WHICH IS THE PREVIOUSLY

2202
01:32:27,800 --> 01:32:30,520
CALLED THE BY PASS BUDGET.

2203
01:32:30,520 --> 01:32:31,160
IT'S ALL YOURS.

2204
01:32:31,160 --> 01:32:33,240
>>THANK YOU.

2205
01:32:33,240 --> 01:32:34,840
THANK YOU, EVERYONE FOR GIVING

2206
01:32:34,840 --> 01:32:35,680
ME THIS OPPORTUNITY.

2207
01:32:35,680 --> 01:32:38,280
WE USUALLY DO THIS AT THE

2208
01:32:38,280 --> 01:32:40,560
SEPTEMBER NCAB MEETING BUT THIS

2209
01:32:40,560 --> 01:32:42,920
YEAR THE FY '24 ANNUAL PLAN EX

2210
01:32:42,920 --> 01:32:45,920
BUDGET PRO POSAL WAS RELEASED ON

2211
01:32:45,920 --> 01:32:48,080
SEPTEMBER 15th SO IT WAS AFTER

2212
01:32:48,080 --> 01:32:49,560
THE SEPTEMBER MEETING AND BEFORE

2213
01:32:49,560 --> 01:32:51,320
Dr. BERTAGNOLLI TOOK THE HELM

2214
01:32:51,320 --> 01:32:52,320
OF THE NCI.

2215
01:32:52,320 --> 01:32:54,000
SO I'M GOING TO TAKE A FEW

2216
01:32:54,000 --> 01:32:55,960
MINUTES TO WALK YOU THROUGH THIS

2217
01:32:55,960 --> 01:32:56,600
YEAR'S PLAN.

2218
01:32:56,600 --> 01:32:59,000
SO NEXT SLIDE, PLEASE.

2219
01:32:59,000 --> 01:33:00,360
AS YOU HAVE ALREADY DISCUSSED

2220
01:33:00,360 --> 01:33:02,000
BUT JUST FOR THE SAKE OF

2221
01:33:02,000 --> 01:33:04,240
COMPLETENESS TO REWIND EVERYONE

2222
01:33:04,240 --> 01:33:05,520
AGAIN THAT THE NATIONAL CANCER

2223
01:33:05,520 --> 01:33:08,080
ACT GIVES NCI THE AUTHORITY TO

2224
01:33:08,080 --> 01:33:09,520
DO THIS AND THE LANGUAGE THERE

2225
01:33:09,520 --> 01:33:11,520
WAS REALLY -- IT GIVES US THE

2226
01:33:11,520 --> 01:33:14,480
ABILITY TO PROVIDE OUR

2227
01:33:14,480 --> 01:33:16,000
PROFESSIONAL JUDGMENT EACH YEAR

2228
01:33:16,000 --> 01:33:17,520
ON THE BUDGET NEEDED TO

2229
01:33:17,520 --> 01:33:18,520
ADMINISTER THE NATIONAL CANCER

2230
01:33:18,520 --> 01:33:19,880
PROGRAM AND IT WAS INTENDED TO

2231
01:33:19,880 --> 01:33:22,040
BE DELIVERED DIRECTLY TO THE

2232
01:33:22,040 --> 01:33:23,720
PRESIDENT FOR REVIEW BY

2233
01:33:23,720 --> 01:33:24,800
CONGRESS.

2234
01:33:24,800 --> 01:33:26,520
AGAIN, AS WAS ALREADY ALLUDED TO

2235
01:33:26,520 --> 01:33:28,760
IT WAS SIGNED INTO LAW TO 1971

2236
01:33:28,760 --> 01:33:32,960
AND NOW THE PRESIDENT IS TALKING

2237
01:33:32,960 --> 01:33:35,440
ABOUT REAUTHORIZING IT.

2238
01:33:35,440 --> 01:33:38,440
IN 2022 THE NCI CELEBRATED OR

2239
01:33:38,440 --> 01:33:39,760
COMMEMORATED THE ANNIVERSARY OF

2240
01:33:39,760 --> 01:33:41,920
THE SIGNING WITH A YEAR LONG

2241
01:33:41,920 --> 01:33:42,600
ENGAGEMENT CAMPAIGN AND WE'RE

2242
01:33:42,600 --> 01:33:44,760
BUILDING ON THE MOMENTUM AROUND

2243
01:33:44,760 --> 01:33:45,520
ENGAGING EVERYONE IN THE

2244
01:33:45,520 --> 01:33:49,360
COMMITMENT TO CANCER RESEARCH.

2245
01:33:49,360 --> 01:33:52,000
SO, THE PLAN IN ITS ESSENCE,

2246
01:33:52,000 --> 01:33:53,160
WHAT WE PREVIOUSLY USED TO REFER

2247
01:33:53,160 --> 01:33:55,840
TO AS THE BY PASS BUDGET AND WE

2248
01:33:55,840 --> 01:33:57,600
REBRAND IT AS THE NCI ANNUAL

2249
01:33:57,600 --> 01:33:59,360
PLAN AND BUDGET PROPOSAL

2250
01:33:59,360 --> 01:34:00,480
CONTAINS TWO MAIN COMPONENTS

2251
01:34:00,480 --> 01:34:01,080
EVERY YEAR.

2252
01:34:01,080 --> 01:34:02,960
THE FIRST IS THE IMPORTANT

2253
01:34:02,960 --> 01:34:04,240
PROFESSIONAL JUDGMENT BUDGET,

2254
01:34:04,240 --> 01:34:05,360
AGAIN, REALLY THIS IS MEANT TO

2255
01:34:05,360 --> 01:34:07,320
BE AN ASPIRATIONAL BUDGET

2256
01:34:07,320 --> 01:34:08,720
PROPOSAL TO COMMUNICATE THE

2257
01:34:08,720 --> 01:34:10,080
OPTIMAL FUNDING NEEDED EVERY

2258
01:34:10,080 --> 01:34:13,840
YEAR TO MAKE PROGRESS AGAINST

2259
01:34:13,840 --> 01:34:16,840
CANCER AND THE ANNUAL PLAN

2260
01:34:16,840 --> 01:34:18,480
NARRATIVE THE DYNAMIC STRATEGIC

2261
01:34:18,480 --> 01:34:20,720
PLAN GIVES US THE CHANCE TO

2262
01:34:20,720 --> 01:34:22,400
DISCUSS OUR PRIORITIES SUCH AS

2263
01:34:22,400 --> 01:34:23,320
SUPPORTING INVESTIGATORS

2264
01:34:23,320 --> 01:34:24,880
INITIATED RESEARCH AND RAISING

2265
01:34:24,880 --> 01:34:27,840
THE RO1 PAY LINES AND HIGHLIGHT

2266
01:34:27,840 --> 01:34:29,640
SCIENTIFIC OPPORTUNITIES.

2267
01:34:29,640 --> 01:34:31,040
IT ALSO FULFILLS THE

2268
01:34:31,040 --> 01:34:32,000
CONGRESSIONAL REQUIREMENT THAT

2269
01:34:32,000 --> 01:34:35,120
WAS INCLUDED IN THE 21st CENTS

2270
01:34:35,120 --> 01:34:37,880
RECURES ACT THAT EACH AND EVERY

2271
01:34:37,880 --> 01:34:39,160
NIH OFFICE INSTITUTE AND CENTER

2272
01:34:39,160 --> 01:34:42,240
HAVE A STRATEGIC PLAN.

2273
01:34:42,240 --> 01:34:44,480
SO, THE PLAN THAT WE PUT OUT

2274
01:34:44,480 --> 01:34:45,600
EVERY YEAR FULFILLS THAT

2275
01:34:45,600 --> 01:34:46,040
REQUIREMENT.

2276
01:34:46,040 --> 01:34:49,480
NEXT SLIDE, PLEASE.

2277
01:34:49,480 --> 01:34:50,960
SO THE PLAN IS RELEASED TWO

2278
01:34:50,960 --> 01:34:52,320
YEARS AHEAD OF TIME SO BUILDING

2279
01:34:52,320 --> 01:34:54,760
ON WHAT PATRICK WAS SAYING, WE

2280
01:34:54,760 --> 01:34:58,720
RELEASED THE FY24 ANNUAL PLAN IN

2281
01:34:58,720 --> 01:35:01,240
SEPTEMBER OF FY '22.

2282
01:35:01,240 --> 01:35:04,160
SO IT'S TWO YEARS AHEAD OF TIME.

2283
01:35:04,160 --> 01:35:05,480
AND THAT RELEASE REALLY ALIGNS

2284
01:35:05,480 --> 01:35:06,640
WITH THE TIMING OF THE FOURTH

2285
01:35:06,640 --> 01:35:07,800
COMING PRESIDENT'S BUDGET.

2286
01:35:07,800 --> 01:35:10,760
SO WHEN WE RELEASED THE FY24

2287
01:35:10,760 --> 01:35:12,440
ANNUAL PLAN AND BUDGET PROPOSAL

2288
01:35:12,440 --> 01:35:15,400
IN THE FALL, WE'RE WAITING THEN

2289
01:35:15,400 --> 01:35:16,320
THE 2024 PRESIDENT'S BUDGET

2290
01:35:16,320 --> 01:35:17,880
WHICH PATRICK JUST TOLD US WILL

2291
01:35:17,880 --> 01:35:20,400
BE RELEASED ON MARCH 9th.

2292
01:35:20,400 --> 01:35:22,160
IT WILL PRE-EMPT THAT TO BE PART

2293
01:35:22,160 --> 01:35:23,480
OF THE CONSIDERATIONS.

2294
01:35:23,480 --> 01:35:25,920
THIS YEAR'S PLAN INCLUDES A

2295
01:35:25,920 --> 01:35:27,680
MESSAGE FROM THEN ACTING

2296
01:35:27,680 --> 01:35:30,640
DIRECTOR DOUG LOWY, THE PJB OR

2297
01:35:30,640 --> 01:35:33,720
THE PROFESSIONAL BUDGET BUDGET

2298
01:35:33,720 --> 01:35:35,560
TABLE AND NARRATIVE.

2299
01:35:35,560 --> 01:35:37,160
STORIES FROM PATIENTS AND

2300
01:35:37,160 --> 01:35:38,400
RESEARCHERS AND IT'S INTEGRATED

2301
01:35:38,400 --> 01:35:41,840
WITHIN THE CANCER.GOV ENTERPRISE

2302
01:35:41,840 --> 01:35:43,840
WEBSITE SO IT COVERS NCI

2303
01:35:43,840 --> 01:35:44,960
SCIENTIFIC VISION AND PRIORITIES

2304
01:35:44,960 --> 01:35:47,320
ACROSS THE PORTFOLIO.

2305
01:35:47,320 --> 01:35:48,440
IN ADDITION THE ANNUAL PLAN

2306
01:35:48,440 --> 01:35:50,320
INCLUDES HIGHLIGHTED SCIENTIFIC

2307
01:35:50,320 --> 01:35:50,800
OPPORTUNITIES.

2308
01:35:50,800 --> 01:35:52,480
IN THE PAST FEW YEARS, WE'VE

2309
01:35:52,480 --> 01:35:54,200
BEEN FOCUSING ON HIGHLIGHTING

2310
01:35:54,200 --> 01:35:56,280
THREE OR FOUR OPPORTUNITIES IN

2311
01:35:56,280 --> 01:35:59,160
SOME DEPTH AS OPPOSED TO LISTING

2312
01:35:59,160 --> 01:35:59,880
DIFFERENT OPPORTUNITIES.

2313
01:35:59,880 --> 01:36:01,840
I'M GOING TO TALK ABOUT THE

2314
01:36:01,840 --> 01:36:02,520
HIGHLIGHTED SCIENTIFIC

2315
01:36:02,520 --> 01:36:04,000
OPPORTUNITIES ON THE NEXT SLIDE.

2316
01:36:04,000 --> 01:36:06,240
BUT BEFORE I DO THAT, I WANTED

2317
01:36:06,240 --> 01:36:07,760
TO MENTION, COULD YOU GO BACK,

2318
01:36:07,760 --> 01:36:08,520
PLEASE?

2319
01:36:08,520 --> 01:36:08,880
THANK YOU.

2320
01:36:08,880 --> 01:36:10,520
I WANTED TO MENTION THAT THERE'S

2321
01:36:10,520 --> 01:36:12,560
ALSO APP EXECUTIVE SUMMARY WHICH

2322
01:36:12,560 --> 01:36:14,200
IS PART OF THE ANNUAL PLANNED

2323
01:36:14,200 --> 01:36:16,240
PACKAGE THAT YOU CAN DOWNLOAD

2324
01:36:16,240 --> 01:36:17,920
FROM CAP SER.GOV.

2325
01:36:17,920 --> 01:36:21,920
THE AT A GLANCE DOCUMENT

2326
01:36:21,920 --> 01:36:24,440
INCLUDES THE DIRECTOR'S MESSAGE,

2327
01:36:24,440 --> 01:36:25,840
PROFESSIONAL BUDGET TABLE,

2328
01:36:25,840 --> 01:36:27,480
BUDGET NARRATIVE AND KEY MESSAGE

2329
01:36:27,480 --> 01:36:29,360
WHICH THIS YEAR INCLUDES SEVERAL

2330
01:36:29,360 --> 01:36:30,280
OPPORTUNITIES TO BUILD ON THE

2331
01:36:30,280 --> 01:36:34,320
SUCCESS OF THE CANCER MOONSHOT.

2332
01:36:34,320 --> 01:36:39,440
THANK YOU, SO, THE HIGHLIGHTED

2333
01:36:39,440 --> 01:36:47,600
SCIENTIFIC OPPORTUNITY NOT --

2334
01:36:47,600 --> 01:36:50,120
APPARENTLY MY DOG WANTS TO

2335
01:36:50,120 --> 01:36:50,480
COMMENT.

2336
01:36:50,480 --> 01:36:53,040
WE TOOK THE APPROACH TO USE

2337
01:36:53,040 --> 01:36:55,000
IMAGES AND FACTOIDS SEEN ON THIS

2338
01:36:55,000 --> 01:36:57,640
SLIDE TO CAPTURE THE PROBLEM OR

2339
01:36:57,640 --> 01:36:58,400
THE CHALLENGED THAT EACH OF THE

2340
01:36:58,400 --> 01:36:59,800
TOPICS IS TRYING TO ADDRESS SO

2341
01:36:59,800 --> 01:37:02,480
IF YOU START AT THE TOP-LEFT,

2342
01:37:02,480 --> 01:37:06,440
THE MAP HIGHLIGHTS OPPORTUNITIES

2343
01:37:06,440 --> 01:37:08,280
PLAN HIGHLIGHTS CANCER SCREENING

2344
01:37:08,280 --> 01:37:14,040
THROUGH DETECTION AND IT WAS

2345
01:37:14,040 --> 01:37:16,720
LAUNCH TO TEST A SIM TO THE ACHE

2346
01:37:16,720 --> 01:37:17,600
MULTI CANCER DETECTION AND THE

2347
01:37:17,600 --> 01:37:20,400
NEXT TOPIC MOVING DOWN,

2348
01:37:20,400 --> 01:37:21,600
ADDRESSES HARNESSING THE POWER

2349
01:37:21,600 --> 01:37:23,960
OF CELL THERAPY TO TREAT SOLID

2350
01:37:23,960 --> 01:37:24,480
TUMORS.

2351
01:37:24,480 --> 01:37:26,520
AND SO AS YOU KNOW, THERE ARE

2352
01:37:26,520 --> 01:37:28,240
FDA APPROVED THERAPIES FOR

2353
01:37:28,240 --> 01:37:30,280
LIQUID TUMORS BUT WE DIDN'T HAVE

2354
01:37:30,280 --> 01:37:32,040
THE SAME SUCCESS IN SOLID TUMORS

2355
01:37:32,040 --> 01:37:33,920
SO THE CONTENT FOCUSES ON THE

2356
01:37:33,920 --> 01:37:35,800
NEED FOR MORE RESEARCH TO

2357
01:37:35,800 --> 01:37:37,280
OVERCOME BARRIERS TO CELL

2358
01:37:37,280 --> 01:37:39,920
THERAPY FOR SOLID TUMORS AND IT

2359
01:37:39,920 --> 01:37:41,360
ALSO INTRODUCES THE CANCER

2360
01:37:41,360 --> 01:37:43,240
ADOPTIVE CELLULAR THERAPY

2361
01:37:43,240 --> 01:37:44,880
NETWORK WHICH IS FOCUSES ON

2362
01:37:44,880 --> 01:37:47,280
EARLY STAGE CLINICAL TESTING OF

2363
01:37:47,280 --> 01:37:49,360
NOVEL CELL THERAPIES FOR SOLID

2364
01:37:49,360 --> 01:37:49,600
TUMORS.

2365
01:37:49,600 --> 01:37:52,760
THE THIRD TOPIC ADDRESSES NCI'S

2366
01:37:52,760 --> 01:37:54,480
CONTINUING FOCUS TO INCREASE

2367
01:37:54,480 --> 01:37:54,840
HEALTH EQUITY.

2368
01:37:54,840 --> 01:37:56,520
AND IT'S FOCUSED ON THE

2369
01:37:56,520 --> 01:37:57,880
CONNECTION BETWEEN PERSISTENT

2370
01:37:57,880 --> 01:37:59,320
POVERTY AND INCREASED CANCER

2371
01:37:59,320 --> 01:38:01,560
RISK AND MORTALITY.

2372
01:38:01,560 --> 01:38:06,800
CANCER DEATH RATES ARE 12%

2373
01:38:06,800 --> 01:38:07,920
HIGHER IN COUNCIL TEE THAT'S

2374
01:38:07,920 --> 01:38:09,480
POVERTY THAN OTHER U.S. COUNTIES

2375
01:38:09,480 --> 01:38:11,040
AND THE MAJORITY OF THOSE

2376
01:38:11,040 --> 01:38:13,280
COUNTIES AS DEFACTOID ARE IN

2377
01:38:13,280 --> 01:38:13,800
RURAL AREAS.

2378
01:38:13,800 --> 01:38:17,400
IT WAS DISCUSSED IN THE PREVIOUS

2379
01:38:17,400 --> 01:38:17,720
SUBCOMMITTEE.

2380
01:38:17,720 --> 01:38:19,480
NCI IS FUNDING RESEARCH TO

2381
01:38:19,480 --> 01:38:20,800
UNDERSTAND HOW FACTORS SUCH AS

2382
01:38:20,800 --> 01:38:22,760
EXPOSURE TO CAP SER CAUSING

2383
01:38:22,760 --> 01:38:24,480
AGENTS, INCREASE STRESS, AND

2384
01:38:24,480 --> 01:38:26,840
LACK OF ACCESS TO QUALITY

2385
01:38:26,840 --> 01:38:29,800
HEALTHCARE AMONG OTHERS CAN

2386
01:38:29,800 --> 01:38:31,400
INTERSECT TO EFFECT CANCER

2387
01:38:31,400 --> 01:38:32,240
OUTCOMES FOR PEOPLE LIVING IN

2388
01:38:32,240 --> 01:38:34,040
YEARS OF PERSISTENT POVERTY.

2389
01:38:34,040 --> 01:38:35,000
WE'RE WORK TO GO BETTER

2390
01:38:35,000 --> 01:38:36,040
UNDERSTAND THIS PROBLEM AND

2391
01:38:36,040 --> 01:38:37,680
WE'RE ALSO TESTING INTERVENTIONS

2392
01:38:37,680 --> 01:38:38,880
AT THE INDIVIDUAL, THE

2393
01:38:38,880 --> 01:38:40,360
COMMUNITY, AND THE POPULATION

2394
01:38:40,360 --> 01:38:41,960
LEVEL TO TRY TO EFFECT CHANGE

2395
01:38:41,960 --> 01:38:45,000
AND CANCER OUTCOMES IN THESE

2396
01:38:45,000 --> 01:38:45,560
COMMUNITIES.

2397
01:38:45,560 --> 01:38:48,120
THE FINAL TOPIC ADDRESSES THE

2398
01:38:48,120 --> 01:38:50,120
PROBLEM OF TACKLING

2399
01:38:50,120 --> 01:38:52,120
TRADITIONALLY UNDRUGABLE CANCER

2400
01:38:52,120 --> 01:38:53,320
TARGETS WITH NEW APPROACHES TO

2401
01:38:53,320 --> 01:38:54,560
DRUG DESIGN.

2402
01:38:54,560 --> 01:38:56,680
AND Dr. BARK ERA LEWDED TO

2403
01:38:56,680 --> 01:38:58,800
THIS WHEN SHE COMMENTED ON THE

2404
01:38:58,800 --> 01:39:00,560
PROMISE THAT WE'RE NOW REALIZING

2405
01:39:00,560 --> 01:39:05,000
OF ALL OF THE RESEARCH INTO

2406
01:39:05,000 --> 01:39:08,240
GENOMICS AND SO WE THINK THE

2407
01:39:08,240 --> 01:39:09,240
LONG-TERM INVESTMENTS AND

2408
01:39:09,240 --> 01:39:10,880
UNDERSTANDING CANCER AND A PRIME

2409
01:39:10,880 --> 01:39:13,920
EXAMPLE IS THE RAS ON KA GENE

2410
01:39:13,920 --> 01:39:14,880
ARE PAYING OFF.

2411
01:39:14,880 --> 01:39:16,560
RESEARCHERS HAVE THE ABILITY TO

2412
01:39:16,560 --> 01:39:17,240
COMBINE MORE KNOWLEDGE ABOUT

2413
01:39:17,240 --> 01:39:19,000
CANCER BIOLOGY THAN EVER BEFORE.

2414
01:39:19,000 --> 01:39:23,720
WITH IMPORTANT ADVANCES IN MA

2415
01:39:23,720 --> 01:39:25,600
DISH ENAL AND IMAGING AND SO

2416
01:39:25,600 --> 01:39:27,040
THAT WE CAN ENVISION A FUTURE

2417
01:39:27,040 --> 01:39:28,800
WHERE NO CANCER TARGETS ARE

2418
01:39:28,800 --> 01:39:35,160
CONSIDERED UNDRUGABLE.

2419
01:39:35,160 --> 01:39:36,880
BEFORE WE TURN TO THE BUDGET,

2420
01:39:36,880 --> 01:39:38,760
THE ANNUAL PLAN COVERS THE

2421
01:39:38,760 --> 01:39:40,560
ENTIRETY OF NCI'S PORTFOLIO FROM

2422
01:39:40,560 --> 01:39:42,280
THE FUNDAMENTAL CANCER BIOLOGY

2423
01:39:42,280 --> 01:39:44,280
THAT WE SUPPORT TO POPULATION

2424
01:39:44,280 --> 01:39:47,960
LEVEL CANCER CONTROL, AND

2425
01:39:47,960 --> 01:39:49,720
BUILDING A DIVERSE AND INCLUSIVE

2426
01:39:49,720 --> 01:39:51,320
WORKFORCE AND SUPPORTING KEY

2427
01:39:51,320 --> 01:39:52,320
INFRASTRUCTURE SUCH AS THE

2428
01:39:52,320 --> 01:39:53,280
CANCER CENTER PROGRAMS AND THE

2429
01:39:53,280 --> 01:39:56,600
CLIP CAL TRIALS NETWORKS SO THE

2430
01:39:56,600 --> 01:39:57,800
ANNUAL PLAN IN THE WEBSITE

2431
01:39:57,800 --> 01:40:02,960
COVERS ALL OF NCI'S PRIORITIES

2432
01:40:02,960 --> 01:40:04,960
FOR THESE AREAS.

2433
01:40:04,960 --> 01:40:06,640
NOW TURNING TO THE BUDGET.

2434
01:40:06,640 --> 01:40:08,800
THE FY24 PROFESSIONAL BUDGET

2435
01:40:08,800 --> 01:40:11,120
PUGET IS REALLY WHAT WE WERE

2436
01:40:11,120 --> 01:40:12,360
REFERRING TO AS A BOLD REQUEST

2437
01:40:12,360 --> 01:40:13,880
FOR CANCER RESEARCH AND IT'S

2438
01:40:13,880 --> 01:40:16,040
REALLY INTENDED TO CAPITALIZE ON

2439
01:40:16,040 --> 01:40:17,120
ALL OF THE OPPORTUNITIES TO

2440
01:40:17,120 --> 01:40:18,360
ACHIEVE THE PRESIDENT'S GOALS OF

2441
01:40:18,360 --> 01:40:21,480
ENDING CANCER AS WE KNOW IT FOR

2442
01:40:21,480 --> 01:40:23,080
ALL PEOPLE WHICH PATRICK

2443
01:40:23,080 --> 01:40:24,160
HIGHLIGHTED IN HIS TALK AND THE

2444
01:40:24,160 --> 01:40:25,680
NUMBER OF TIMES AND IMPORTANCE

2445
01:40:25,680 --> 01:40:26,520
TO THIS PRESIDENT.

2446
01:40:26,520 --> 01:40:28,120
IT BUILDS ON THE SUCCESSES OF

2447
01:40:28,120 --> 01:40:29,880
THE CANCER MOONSHOT AND IT

2448
01:40:29,880 --> 01:40:32,200
INCLUDES FUNDING FOR INCREASING

2449
01:40:32,200 --> 01:40:33,920
THE PAYLINE.

2450
01:40:33,920 --> 01:40:37,240
CONTINUING NCI'S COMMITMENT TO

2451
01:40:37,240 --> 01:40:38,920
ELIMINATE CANCER DISPARITIES AND

2452
01:40:38,920 --> 01:40:40,080
EXPAND CLINICAL TRIALS AND

2453
01:40:40,080 --> 01:40:42,000
CANCER CARE DELIVERY RESEARCH.

2454
01:40:42,000 --> 01:40:45,320
THE NEXT SLIDE, PLEASE.

2455
01:40:45,320 --> 01:40:46,920
THE BUDGET TABLE AND THAT BOLD

2456
01:40:46,920 --> 01:40:48,840
REQUEST OF NEARLY $10 BILLION.

2457
01:40:48,840 --> 01:40:54,200
SO THE FY24 PROFESSIONAL BUDGET

2458
01:40:54,200 --> 01:40:55,880
PROPOSAL IS FOR $10 BILLION AND

2459
01:40:55,880 --> 01:40:58,280
IT BEGINS WITH THE FY23

2460
01:40:58,280 --> 01:41:00,920
PROFESSIONAL BUDGET BUDGET ASK

2461
01:41:00,920 --> 01:41:03,720
AND REQUEST A $2.4 BILLION

2462
01:41:03,720 --> 01:41:05,320
INCREASE OVER THAT ASK.

2463
01:41:05,320 --> 01:41:07,760
THAT IS ABOUT A $2.7 BILLION

2464
01:41:07,760 --> 01:41:10,560
INCREASE OVER THE FY '23 ENACTED

2465
01:41:10,560 --> 01:41:13,000
BUDGET OF $7.3 BILLION SO AS YOU

2466
01:41:13,000 --> 01:41:14,720
KNOW, WE DIDN'T HAVE THE ENACTED

2467
01:41:14,720 --> 01:41:17,760
NUMBER WHEN WE PUT THIS

2468
01:41:17,760 --> 01:41:19,000
PROFESSIONAL BUDGET TOGETHER

2469
01:41:19,000 --> 01:41:22,080
EACH SUMMER.

2470
01:41:22,080 --> 01:41:23,200
AGAIN, AS YOU CAN SEE ON THE

2471
01:41:23,200 --> 01:41:25,160
TABLE, IT INCLUDES MONEY FOR ALL

2472
01:41:25,160 --> 01:41:28,600
YEARS OF THE PORTFOLIO, AND THEN

2473
01:41:28,600 --> 01:41:31,120
SOME ADDITIONAL KEY FUNDING FOR

2474
01:41:31,120 --> 01:41:34,920
CLINICAL RESEARCH.

2475
01:41:34,920 --> 01:41:36,000
SO, THIS GRAPH JUST LET'S YOU

2476
01:41:36,000 --> 01:41:37,560
TRACK THE BUDGET REQUEST OVER

2477
01:41:37,560 --> 01:41:38,880
THE LAST FIVE YEARS SO YOU CAN

2478
01:41:38,880 --> 01:41:41,040
SEE THE COMPARISONS I NOTED

2479
01:41:41,040 --> 01:41:43,760
BETWEEN '23 AND THE '24 PJB AND

2480
01:41:43,760 --> 01:41:44,960
THE LAST SLIDE.

2481
01:41:44,960 --> 01:41:47,200
THE PJB PROPOSALS FOR THE LAST

2482
01:41:47,200 --> 01:41:48,600
FIVE YEARS ARE SHOWN IN RED AND

2483
01:41:48,600 --> 01:41:51,400
THE ENACTED BUDGETS ARE SHOWN IN

2484
01:41:51,400 --> 01:41:52,000
BLUE.

2485
01:41:52,000 --> 01:41:53,560
AS PATRICK ALREADY TALKED ABOUT,

2486
01:41:53,560 --> 01:41:55,240
BUT I WANTED TO KNOW HEIT AS

2487
01:41:55,240 --> 01:41:57,240
WELL, THIS IS THE LAST YEAR FOR

2488
01:41:57,240 --> 01:41:57,920
MOONSHOT FUNDING THROUGH THE

2489
01:41:57,920 --> 01:42:00,320
CURES ACT SO THE FY '23 ENACTED

2490
01:42:00,320 --> 01:42:05,880
BUDGET OF $7.3 BILLION INCLUDES

2491
01:42:05,880 --> 01:42:08,000
THAT $2.6 MILLION FOR THE CURES

2492
01:42:08,000 --> 01:42:10,960
ACT FUNDING AND ALL SHOWN ON

2493
01:42:10,960 --> 01:42:14,400
THIS SLIDE, INCLUDES THAT MOON

2494
01:42:14,400 --> 01:42:16,080
SHOOT FUNDING WHICH WE'LL LOSE

2495
01:42:16,080 --> 01:42:19,560
IN FY '24.

2496
01:42:19,560 --> 01:42:22,920
THIS YEAR'S PLAN ALSO INCLUDED A

2497
01:42:22,920 --> 01:42:25,520
NEW BUDGET INFO GRAPHIC THAT WE

2498
01:42:25,520 --> 01:42:27,640
WANTED TO PUT INTO HELP TO

2499
01:42:27,640 --> 01:42:29,320
EXPLAIN WHY WE NEED SUSTAINED

2500
01:42:29,320 --> 01:42:31,600
ANNUAL BUDGET INCREASES TO FUND

2501
01:42:31,600 --> 01:42:32,880
MORE RESEARCH PROJECTS GRANTS

2502
01:42:32,880 --> 01:42:34,080
AND RAISE THE PAYLINE.

2503
01:42:34,080 --> 01:42:35,520
IT'S THE LAY VERSION OF THE

2504
01:42:35,520 --> 01:42:36,920
TABLE THAT PATRICK SHOWED YOU.

2505
01:42:36,920 --> 01:42:38,680
USING THE SAME KIND OF STAIR

2506
01:42:38,680 --> 01:42:40,080
STEP APPROACH ONLY INVERT INSIDE

2507
01:42:40,080 --> 01:42:41,120
THIS GRAPHIC.

2508
01:42:41,120 --> 01:42:43,240
AND THE ENTIRE GRAPHIC IS SHOWN

2509
01:42:43,240 --> 01:42:44,600
ON THE LEFT OF THE SLIDE AND I

2510
01:42:44,600 --> 01:42:45,680
APPRECIATED IT'S VERY HARD TO

2511
01:42:45,680 --> 01:42:48,640
SEE HERE AS IT'S A LONG VERTICAL

2512
01:42:48,640 --> 01:42:50,520
GRAPHIC, SO I ENCOURAGE YOU TO

2513
01:42:50,520 --> 01:42:52,200
VIEW IT ON CANCER.GOV.

2514
01:42:52,200 --> 01:42:54,240
BUT STARTING AT THE TOP OF THE

2515
01:42:54,240 --> 01:42:55,880
GRAPHIC, WE HIGHLIGHT THE IDEA

2516
01:42:55,880 --> 01:42:57,760
OR THE CONCEPT THAT EVERY YEAR

2517
01:42:57,760 --> 01:42:59,520
WE RECEIVE MANY, MANY RESEARCH

2518
01:42:59,520 --> 01:43:01,000
PROPOSALS AND WHEN WE FUND THE

2519
01:43:01,000 --> 01:43:03,480
PROPOSAL IT'S A MULTI-YEAR

2520
01:43:03,480 --> 01:43:03,800
COMMITMENT.

2521
01:43:03,800 --> 01:43:04,680
NOW I KNOW THAT AWFUL YOU ARE

2522
01:43:04,680 --> 01:43:06,680
FAMILIAR WITH THE CONCEPT OF OUT

2523
01:43:06,680 --> 01:43:08,920
YEAR COSTS BUT MANY OF OUR

2524
01:43:08,920 --> 01:43:10,360
AUDIENCES ARE NOT SO THIS WAS

2525
01:43:10,360 --> 01:43:12,640
OUR ATTEMPT TO GIVE THEM A

2526
01:43:12,640 --> 01:43:13,880
VISUAL TO UNDERSTAND THIS

2527
01:43:13,880 --> 01:43:15,520
CONCEPT SO THE MAIN PANEL OF THE

2528
01:43:15,520 --> 01:43:17,720
GRAPHIC WHICH IS IN LARGED HERE,

2529
01:43:17,720 --> 01:43:19,440
ATTEMPTS TO PROVIDE PEOPLE WITH

2530
01:43:19,440 --> 01:43:21,360
THAT VISUAL TO UNDERSTAND THE

2531
01:43:21,360 --> 01:43:23,240
CONCEPT OF THE OUT YEAR COST AND

2532
01:43:23,240 --> 01:43:24,680
SHOW WHY IN ORDER TO FUND MORE

2533
01:43:24,680 --> 01:43:26,760
NEW GRANTS EACH YEAR WE NEED

2534
01:43:26,760 --> 01:43:29,000
MORE MONEY EACH YEAR.

2535
01:43:29,000 --> 01:43:31,480
AND AS THE GRAPH POINTS OUT AT

2536
01:43:31,480 --> 01:43:34,880
THE BOTTOM, SUSTAINED YEARLY

2537
01:43:34,880 --> 01:43:36,840
BUDGET INCREASES ALLOW US TO

2538
01:43:36,840 --> 01:43:38,080
FUND MORE GRANTS EACH YEAR WHICH

2539
01:43:38,080 --> 01:43:39,840
ALLOW US TO DO SUPPORT MORE NEW

2540
01:43:39,840 --> 01:43:40,400
IDEAS.

2541
01:43:40,400 --> 01:43:42,360
SO THAT WE DON'T MISS ANY

2542
01:43:42,360 --> 01:43:45,480
EMERGING OPPORTUNITIES IN CANCER

2543
01:43:45,480 --> 01:43:47,640
RESEARCH.

2544
01:43:47,640 --> 01:43:51,160
NEXT SLIDE.

2545
01:43:51,160 --> 01:43:53,120
FINALLY, AS IN PAST YEARS, THIS

2546
01:43:53,120 --> 01:43:54,040
YEAR'S PLAN SHARES THE

2547
01:43:54,040 --> 01:43:55,800
EXPERIENCES OF RESEARCHERS AND

2548
01:43:55,800 --> 01:43:56,800
OF PATIENTS WHO HAVE

2549
01:43:56,800 --> 01:43:58,520
PARTICIPATED IN NCI CLINICAL

2550
01:43:58,520 --> 01:43:58,760
TRIALS.

2551
01:43:58,760 --> 01:44:00,360
AND I WANT TO TAKE JUST A MINUTE

2552
01:44:00,360 --> 01:44:05,840
TO TELL YOU ABOUT JUSTIN'S

2553
01:44:05,840 --> 01:44:06,040
STORY.

2554
01:44:06,040 --> 01:44:07,640
JUSTIN AND HIS FAMILY HAVE BEEN

2555
01:44:07,640 --> 01:44:10,560
PART OF THE NCI NATURAL HISTORY

2556
01:44:10,560 --> 01:44:14,480
STUDY SINCE THE MID 19 - 1990s.

2557
01:44:14,480 --> 01:44:17,480
JUSTIN WAS DIAGNOSED WITH VHL

2558
01:44:17,480 --> 01:44:18,840
SYNDROME WHEN I WAS SIX YEARS O

2559
01:44:18,840 --> 01:44:20,240
HIS 20s WERE MARKED WITH

2560
01:44:20,240 --> 01:44:22,040
FREQUENT SURVEILLANCE SCAN,

2561
01:44:22,040 --> 01:44:24,120
TRIPS TO THE HOSPITAL AND

2562
01:44:24,120 --> 01:44:24,680
SURGERIES.

2563
01:44:24,680 --> 01:44:25,880
AND HE THOUGHT THIS WAS THE WAY

2564
01:44:25,880 --> 01:44:27,920
THAT THE REST OF HIS LIFE WOULD

2565
01:44:27,920 --> 01:44:29,520
BE BASED ON WATCHING HIS

2566
01:44:29,520 --> 01:44:30,640
FATHER'S EXPERIENCES.

2567
01:44:30,640 --> 01:44:33,520
AND THEN HE JOINED AN NCI PHASE

2568
01:44:33,520 --> 01:44:37,800
2 CLINICAL TRIAL LED BY

2569
01:44:37,800 --> 01:44:38,680
INTRAMURAL INVESTIGATORS IN THE

2570
01:44:38,680 --> 01:44:39,880
CENTER FOR CANCER RESEARCH AT

2571
01:44:39,880 --> 01:44:42,200
THE NIH CLINICAL CENTER AND IN

2572
01:44:42,200 --> 01:44:43,760
JUSTIN'S OWN WORDS T. IT CHANGED

2573
01:44:43,760 --> 01:44:45,560
HIS LIFE.

2574
01:44:45,560 --> 01:44:47,360
AFTER BEING ON ON THE DRUG FOR A

2575
01:44:47,360 --> 01:44:49,160
PERIOD OF TIME, JUSTIN, IN HIS

2576
01:44:49,160 --> 01:44:51,600
EARLY 30s, FELT COMFORTABLE TO

2577
01:44:51,600 --> 01:44:53,360
TRAVEL INTERNATIONALLY FOR THE

2578
01:44:53,360 --> 01:44:55,520
FIRST TIME, TO GET MARRIED, AND

2579
01:44:55,520 --> 01:44:57,920
AS THE SLIDE SAYS, TO FILL

2580
01:44:57,920 --> 01:44:59,800
OPTIMISTIC ABOUT HIS FUTURE.

2581
01:44:59,800 --> 01:45:02,240
SOME OF YOU MAY KNOW THAT THE

2582
01:45:02,240 --> 01:45:05,160
NCI INTRAMURAL PROGRAM PLAYED A

2583
01:45:05,160 --> 01:45:08,280
ROLE IN UNRAVELING THE BIOLOGY

2584
01:45:08,280 --> 01:45:11,520
OF VHL TUMORS AND IDENTIFYING

2585
01:45:11,520 --> 01:45:13,600
THE VHL GENE IN THE 1990s AND

2586
01:45:13,600 --> 01:45:16,840
TWO NCI EXTRAMURAL RESEARCHERS

2587
01:45:16,840 --> 01:45:19,440
WON THE PRIZE IN 2019 FOR THEIR

2588
01:45:19,440 --> 01:45:20,840
WORK ON HYPOXIA INDUCE ABLE

2589
01:45:20,840 --> 01:45:23,120
FACTOR WHICH IS A CRITICAL

2590
01:45:23,120 --> 01:45:25,400
COMPONENT OF VHL TUMOR FORMATION

2591
01:45:25,400 --> 01:45:27,880
AND THE TARGET OF.

2592
01:45:27,880 --> 01:45:29,280
SO WHILE WE HAVE NOT ACHIEVED

2593
01:45:29,280 --> 01:45:31,200
DIRECT TARGETING OF VHL, THE

2594
01:45:31,200 --> 01:45:32,120
DECADES OF RESEARCH TO

2595
01:45:32,120 --> 01:45:33,800
UNDERSTAND THE BIOLOGY OF THE

2596
01:45:33,800 --> 01:45:36,840
FORMATION OF VHL MEDIATED TUMORS

2597
01:45:36,840 --> 01:45:41,000
LED TO 2092 IS FDA APPROVAL OF

2598
01:45:41,000 --> 01:45:44,840
BELL SOOT A FAN TO TREAT THE

2599
01:45:44,840 --> 01:45:48,120
TUMORS.

2600
01:45:48,120 --> 01:45:52,760
MANY SO IN CLOSING, THE FY24

2601
01:45:52,760 --> 01:45:54,640
ANNUAL PLAN HAS A NUMBER OF KEY

2602
01:45:54,640 --> 01:45:55,360
MESSAGES.

2603
01:45:55,360 --> 01:45:56,880
IT STARTS WITH A BOLD

2604
01:45:56,880 --> 01:45:58,280
ASPIRATIONAL BUDGET PROPOSAL

2605
01:45:58,280 --> 01:46:00,200
REALLY DESIGNED TO CAPITALIZE ON

2606
01:46:00,200 --> 01:46:01,600
THE SCIENTIFIC OPPORTUNITIES

2607
01:46:01,600 --> 01:46:02,440
BEFORE US.

2608
01:46:02,440 --> 01:46:04,640
TO END CANCER AS WE KNOW IT FOR

2609
01:46:04,640 --> 01:46:04,800
ALL.

2610
01:46:04,800 --> 01:46:06,520
TO BUILD ON THE SUCCESSES OF THE

2611
01:46:06,520 --> 01:46:07,840
CANCER MOONSHOT AND TO CONTINUE

2612
01:46:07,840 --> 01:46:10,640
TO INCREASE OUR INVESTMENTS IN

2613
01:46:10,640 --> 01:46:13,360
INVESTIGATOR INITIATED AWARDS.

2614
01:46:13,360 --> 01:46:13,720
THANK YOU.

2615
01:46:13,720 --> 01:46:15,600
>>THANK YOU, DIANNE.

2616
01:46:15,600 --> 01:46:18,200
THAT WAS ABSOLUTELY ONE OF THE

2617
01:46:18,200 --> 01:46:20,560
BEST PRESENTATIONS I'VE HEARD OF

2618
01:46:20,560 --> 01:46:22,240
WHAT I CONTINUE TO CALL THE BY

2619
01:46:22,240 --> 01:46:24,520
PASS BUDGET BUT WE'RE NOW

2620
01:46:24,520 --> 01:46:25,680
CALLING THE -- WHAT ARE WE

2621
01:46:25,680 --> 01:46:26,080
CALLING IT NOW?

2622
01:46:26,080 --> 01:46:27,240
>>ANNUAL PLAN.

2623
01:46:27,240 --> 01:46:29,120
>>THE ANNUAL PLAN, OK.

2624
01:46:29,120 --> 01:46:29,640
GOOD.

2625
01:46:29,640 --> 01:46:33,960
I'M WITH THAT.

2626
01:46:33,960 --> 01:46:35,320
WHAT IS REALLY INTERESTING AND

2627
01:46:35,320 --> 01:46:36,560
WHAT WE WANTED DO WITH THE

2628
01:46:36,560 --> 01:46:38,320
COMMITTEE TODAY IS TO SHOW YOU

2629
01:46:38,320 --> 01:46:40,840
WHERE WE ARE, WHAT THEY SORT OF,

2630
01:46:40,840 --> 01:46:42,920
AS PATRICK MENTIONS, SOME OF THE

2631
01:46:42,920 --> 01:46:46,520
KNOWN AND UNKNOWNS AND A LOT OF

2632
01:46:46,520 --> 01:46:47,040
UNKNOWN UNKNOWNS.

2633
01:46:47,040 --> 01:46:51,640
WHERE WE COULD BE WITH THE RIGHT

2634
01:46:51,640 --> 01:46:52,560
KIND OF FUNDING.

2635
01:46:52,560 --> 01:46:55,480
I POINT OUT TO YOU, $10 MILLION

2636
01:46:55,480 --> 01:46:56,680
SOUNDS LIKE A LOT OF MONEY,

2637
01:46:56,680 --> 01:46:57,440
RIGHT.

2638
01:46:57,440 --> 01:46:59,000
IF YOU LOOKED AT THE COST OF

2639
01:46:59,000 --> 01:47:00,360
CANCER AND THE INCREASE COMING

2640
01:47:00,360 --> 01:47:04,520
AND IF YOU LOOK AT THE COST OF

2641
01:47:04,520 --> 01:47:08,320
BUBIOLOGICS SO THIS COMMITTEE

2642
01:47:08,320 --> 01:47:09,720
NEEDS TO THINK ABOUT HOW DO WE

2643
01:47:09,720 --> 01:47:11,560
GET TO THAT $10 MILLION AND WE

2644
01:47:11,560 --> 01:47:14,040
CAN'T GET THERE OVER THE NEXT 25

2645
01:47:14,040 --> 01:47:15,680
YEARS, RIGHT.

2646
01:47:15,680 --> 01:47:17,280
THE PRESIDENT HAS CHALLENGES TO

2647
01:47:17,280 --> 01:47:20,560
REDUCE CANCER BY 50% IN THE NEXT

2648
01:47:20,560 --> 01:47:21,640
A 25 YEARS.

2649
01:47:21,640 --> 01:47:24,800
SOMEONE SOMEWHERE, I'M HOPING IN

2650
01:47:24,800 --> 01:47:26,000
THE NCI, NEEDS TO SIT DOWN AND

2651
01:47:26,000 --> 01:47:27,400
FIGURE OUT IF IT IT TOOK THIS

2652
01:47:27,400 --> 01:47:28,880
MANY DECADES TO GET WHERE WE

2653
01:47:28,880 --> 01:47:30,640
ARE, WHICH IS A PRETTY GOOD

2654
01:47:30,640 --> 01:47:39,480
REDUCTION IN CANCER, WE'RE JUST

2655
01:47:39,480 --> 01:47:40,720
SEEING THIS CURVE I AM FACT US

2656
01:47:40,720 --> 01:47:42,200
IN TERMS OF UNDERSTANDING THE

2657
01:47:42,200 --> 01:47:43,600
BIOLOGY OF CANCER, THAT'S GOING

2658
01:47:43,600 --> 01:47:46,400
TO BE TRANSFORMATIVE, NO

2659
01:47:46,400 --> 01:47:47,000
QUESTION.

2660
01:47:47,000 --> 01:47:49,240
SO, HOW CAN THIS COMMITTEE HELP?

2661
01:47:49,240 --> 01:47:50,440
I GUESS IS ONE OF THE QUESTIONS

2662
01:47:50,440 --> 01:47:52,960
WE WANT TO ASK OURSELVES.

2663
01:47:52,960 --> 01:47:54,920
AND I'M WONDERING IF THERE ARE

2664
01:47:54,920 --> 01:47:56,920
ANY IDEAS FROM THE COMMITTEE

2665
01:47:56,920 --> 01:48:00,080
THAT AREAS WHERE WE THINK WE CAN

2666
01:48:00,080 --> 01:48:04,840
HAVE MONICA ACTUALLY, NOT JUST

2667
01:48:04,840 --> 01:48:07,320
GET THE RESOURCES WE NEED AND

2668
01:48:07,320 --> 01:48:10,080
THINKING ABOUT EVERYTHING FROM

2669
01:48:10,080 --> 01:48:11,800
THE FOUR YEARS THAT WERE

2670
01:48:11,800 --> 01:48:13,320
HIGHLIGHTED WHICH ARE THE

2671
01:48:13,320 --> 01:48:15,880
INVESTMENTS IN THIS ANNUAL PLAN,

2672
01:48:15,880 --> 01:48:17,720
TO SOMEONE OTHER AND YOU CAN SEE

2673
01:48:17,720 --> 01:48:18,920
THEM COMING INVESTMENTS ARE

2674
01:48:18,920 --> 01:48:22,160
GOING TO BE REQUIRED IN NEW

2675
01:48:22,160 --> 01:48:23,280
BIOLOGY AND INFRASTRUCTURE.

2676
01:48:23,280 --> 01:48:27,520
IF YOU RUN A CAP SER C A CANCERU

2677
01:48:27,520 --> 01:48:28,200
THINK ABOUT THAT.

2678
01:48:28,200 --> 01:48:30,200
I USED TO CHAIR THE CANCER STUDY

2679
01:48:30,200 --> 01:48:32,240
SECTION YEARS AGO AND YOU GO TO

2680
01:48:32,240 --> 01:48:37,920
A SITE AND EVERYONE EXPLAINS EXS

2681
01:48:37,920 --> 01:48:38,840
ABOUT THE OVERHEAD.

2682
01:48:38,840 --> 01:48:40,800
YOU ASK IF THEY LIKE HAVING THE

2683
01:48:40,800 --> 01:48:42,680
LIGHTS ON AND THE ELECTRICITY

2684
01:48:42,680 --> 01:48:44,040
THAT THEY GET AND ALL THE OTHER

2685
01:48:44,040 --> 01:48:46,440
THINGS THEY GET.

2686
01:48:46,440 --> 01:48:47,520
THEY DON'T THINK ABOUT THAT.

2687
01:48:47,520 --> 01:48:48,640
WE HAVE TO THINK ABOUT THE

2688
01:48:48,640 --> 01:48:49,960
INFRASTRUCTURE BECAUSE IT'S

2689
01:48:49,960 --> 01:48:51,440
CRITICAL AND COST OF CANCER

2690
01:48:51,440 --> 01:48:52,640
RESEARCH IS GOING UP EVERY

2691
01:48:52,640 --> 01:48:55,240
SINGLE DAY.

2692
01:48:55,240 --> 01:48:57,840
SO LET'S -- AS A COMMITTEE, AS

2693
01:48:57,840 --> 01:48:59,440
INDIVIDUAL MEMBERS OF THIS

2694
01:48:59,440 --> 01:49:00,360
COMMITTEE WITH CERTAIN

2695
01:49:00,360 --> 01:49:01,600
RESPONSIBILITY TO MAKE SURE THAT

2696
01:49:01,600 --> 01:49:04,200
WE GET THIS DONE, WHAT ARE YOUR

2697
01:49:04,200 --> 01:49:04,440
IDEAS?

2698
01:49:04,440 --> 01:49:08,280
WHAT KINDS OF THINGS CAN THIS

2699
01:49:08,280 --> 01:49:13,960
COMMITTEE HELP Dr. BERTAGNOLLI

2700
01:49:13,960 --> 01:49:14,160
WITH?

2701
01:49:14,160 --> 01:49:16,320
I KNOW YOU ARE OUT THERE AND YOU

2702
01:49:16,320 --> 01:49:17,200
MUST HAVE GO AHEAD IDEAS?

2703
01:49:17,200 --> 01:49:19,080
WHAT KINDS OF THINGS CAN WE DO?

2704
01:49:19,080 --> 01:49:20,800
ANY ANALYTICS YOU WOULD LIKE TO

2705
01:49:20,800 --> 01:49:24,000
SEE FROM NCI?

2706
01:49:24,000 --> 01:49:26,960
ANY NOT KIND OF QUESTIONS ABOUT

2707
01:49:26,960 --> 01:49:28,400
HOW FAR THOSE EMPHASIS AREAS ARE

2708
01:49:28,400 --> 01:49:30,520
SELECTED IN TERMS OF HOW THOSE

2709
01:49:30,520 --> 01:49:33,240
COMMITMENT OF DOLLARS COME IN?

2710
01:49:33,240 --> 01:49:34,960
I KNOW IF YOU ARE NOT A CPA AND

2711
01:49:34,960 --> 01:49:38,040
YOU MAY NOT HAVE YOUR MBA BUT

2712
01:49:38,040 --> 01:49:39,320
YOU HAVE TO THINK ABOUT THE

2713
01:49:39,320 --> 01:49:40,600
BUDGET EVERY SINGLE DAY AND I

2714
01:49:40,600 --> 01:49:42,800
HAVE TO SAY, DIANNE, THAT IS ONE

2715
01:49:42,800 --> 01:49:44,640
OF THE BEST REPRESENTATIONS I'VE

2716
01:49:44,640 --> 01:49:47,560
SEEN OF A BUDGET, I DON'T KNOW

2717
01:49:47,560 --> 01:49:49,080
HOW MANY VIEWS YOU'VE GOT THAT

2718
01:49:49,080 --> 01:49:50,800
HAVE BUT IT'S REALLY WELL

2719
01:49:50,800 --> 01:49:53,080
PRESENTED AND VERY CRISP,

2720
01:49:53,080 --> 01:49:54,400
ON-LINE AND IT USED TO BE A

2721
01:49:54,400 --> 01:49:56,160
DOCUMENT ABOUT THIS THICK AND NO

2722
01:49:56,160 --> 01:49:58,320
ONE READ IT HONESTLY.

2723
01:49:58,320 --> 01:50:00,360
EVERYONE CAN LOOK AT THIS ONE

2724
01:50:00,360 --> 01:50:01,640
AND UNDERSTAND IT AND GO TO WORK

2725
01:50:01,640 --> 01:50:04,960
TO HELP US GET IT, I HOPE.

2726
01:50:04,960 --> 01:50:07,120
WHAT DO YOU GUYS HAVE IN TERMS

2727
01:50:07,120 --> 01:50:07,480
OF IDEAS?

2728
01:50:07,480 --> 01:50:10,640
>>ELECTRA.

2729
01:50:10,640 --> 01:50:12,280
>>DISRUPTER.

2730
01:50:12,280 --> 01:50:15,080
I AM CONTINUING MY DISRUPTER

2731
01:50:15,080 --> 01:50:19,960
ROLE.

2732
01:50:19,960 --> 01:50:21,840
SO, DECEMBER WORKING GROUP

2733
01:50:21,840 --> 01:50:25,000
PRESENTED A REPORT THAT SAID

2734
01:50:25,000 --> 01:50:27,000
THAT THE INVESTMENTS BOTH BY NIH

2735
01:50:27,000 --> 01:50:30,880
AND THE NCI IN RESEARCH IN

2736
01:50:30,880 --> 01:50:33,720
VARIOUS UNDER REPRESENTED

2737
01:50:33,720 --> 01:50:38,080
POPULATIONS IS IS WOEFULLY

2738
01:50:38,080 --> 01:50:39,120
APPROXIMATE LOW.

2739
01:50:39,120 --> 01:50:43,120
I WOULD LOVE TO SEE THAT

2740
01:50:43,120 --> 01:50:45,000
HIGHLIGHTED ACROSS ALL OF THOSE

2741
01:50:45,000 --> 01:50:51,040
THOSEHIGHLIGHTED CATEGORIES IN E

2742
01:50:51,040 --> 01:50:51,240
PLAN.

2743
01:50:51,240 --> 01:50:52,640
I DID NOT SEE.

2744
01:50:52,640 --> 01:50:56,920
I SAW IT IN THE LOVELY, I LOVE

2745
01:50:56,920 --> 01:50:58,880
THOSE PICTURES, THE FOCUS ON PER

2746
01:50:58,880 --> 01:51:08,960
IS CYSTCYST APARTMENT PERSIST AI

2747
01:51:08,960 --> 01:51:11,840
LOVE TO BE WRONG BUT I DIDN'T

2748
01:51:11,840 --> 01:51:13,280
SEE THE CORPORATION OF THE

2749
01:51:13,280 --> 01:51:14,840
FINDINGS IN THE RECOMMENDATION

2750
01:51:14,840 --> 01:51:21,200
THAT'S WE PRESENTED AND IS NOW

2751
01:51:21,200 --> 01:51:24,840
ON-LINE IN SEPTEMBER.

2752
01:51:24,840 --> 01:51:27,640
THAT'S MY PIECE.

2753
01:51:27,640 --> 01:51:29,080
>>MAYBE WE CAN CHALLENGE
PEOPLE

2754
01:51:29,080 --> 01:51:30,480
THAT CREATE THESE REPORTS TO

2755
01:51:30,480 --> 01:51:33,000
THINK ABOUT WHAT IS THE BUDGET

2756
01:51:33,000 --> 01:51:33,600
IMPACT?

2757
01:51:33,600 --> 01:51:35,960
WHAT DO YOU ASSESS -- WHERE DO

2758
01:51:35,960 --> 01:51:38,600
YOU ASSESS THE COSTS WILL COME

2759
01:51:38,600 --> 01:51:38,920
FROM IF.

2760
01:51:38,920 --> 01:51:41,240
>>YEAH, I MEAN WE
SUGGESTED

2761
01:51:41,240 --> 01:51:42,320
SOME TARGETING FUNDING AREAS.

2762
01:51:42,320 --> 01:51:52,800
I MEAN SOME FO ANTI-SEMITISM, EY

2763
01:51:52,800 --> 01:51:54,520
REALLY NEED TO A, BE MORE

2764
01:51:54,520 --> 01:51:57,040
INCLUSIVE AND MORE DIRECT IN

2765
01:51:57,040 --> 01:51:58,920
THEIR INCLUSION OF THESE

2766
01:51:58,920 --> 01:52:00,840
POPULATIONS IN THE REGULAR

2767
01:52:00,840 --> 01:52:04,880
RESEARCH THAT THEY'RE DOING AND

2768
01:52:04,880 --> 01:52:08,760
IT'S JUST NOT THOUGHT OF AND

2769
01:52:08,760 --> 01:52:10,520
WHAT A BETTER WAY FOR PEOPLE TO

2770
01:52:10,520 --> 01:52:12,320
INCREASE THIS RESEARCH IS TO

2771
01:52:12,320 --> 01:52:13,760
SAY, YOU KNOW, THIS IS A

2772
01:52:13,760 --> 01:52:14,840
HIGHLIGHT, THAT'S WHAT IS SOME

2773
01:52:14,840 --> 01:52:17,600
OF OUR MONEY IS FOCUSING ON AND

2774
01:52:17,600 --> 01:52:22,160
YOU KNOW, I THINK YOU WILL GET

2775
01:52:22,160 --> 01:52:23,720
PEOPLE FOCUSING ON THAT AREA.

2776
01:52:23,720 --> 01:52:25,200
I DON'T KNOW IF ANYBODY ELSE

2777
01:52:25,200 --> 01:52:30,240
WANTS TO ADD TO THAT.

2778
01:52:30,240 --> 01:52:32,840
>>O ONE THING TO NOTE, IF
YOU

2779
01:52:32,840 --> 01:52:34,960
LOOK AT PATRICK SLIDES THE CURES

2780
01:52:34,960 --> 01:52:40,680
ACT IS A BIG DIFFERENCE.

2781
01:52:40,680 --> 01:52:41,720
I CHAIRED ONE OF THOSE

2782
01:52:41,720 --> 01:52:42,920
COMMITTEES AND IT CHANGED

2783
01:52:42,920 --> 01:52:43,680
EVERYTHING.

2784
01:52:43,680 --> 01:52:45,080
THE REGULATORY PROCESS AND THE

2785
01:52:45,080 --> 01:52:47,720
WAY WE FUND SCIENCE AND HOW

2786
01:52:47,720 --> 01:52:48,560
WE'RE ACCOUNTABLE IN SCIENCE AND

2787
01:52:48,560 --> 01:52:50,000
I HAVE TO SAY, IF YOU THINK YOU

2788
01:52:50,000 --> 01:52:53,000
DON'T HAVE AN IMPACT, AS A

2789
01:52:53,000 --> 01:52:54,440
SCIENTIST, OR IF YOU THINK YOU

2790
01:52:54,440 --> 01:52:56,520
DON'T HAVE AN IMPACT AS AN

2791
01:52:56,520 --> 01:53:02,040
ADVOCATE OUT THERE, YOU CAN.

2792
01:53:02,040 --> 01:53:03,440
AND THE CURES ACT IS A PERFECT

2793
01:53:03,440 --> 01:53:04,360
EXAMPLE OF THAT.

2794
01:53:04,360 --> 01:53:05,560
YOU HAVE AN ADMINISTRATION THAT

2795
01:53:05,560 --> 01:53:09,120
IS LISTENING HERE AND TRYING TO

2796
01:53:09,120 --> 01:53:09,960
REALLY CHANGE THAN THIS WHOLE

2797
01:53:09,960 --> 01:53:14,560
DYNAMIC FOR CA CANCER INCLUDING

2798
01:53:14,560 --> 01:53:16,120
FUNDING AND $10 MILLION IS, I'M

2799
01:53:16,120 --> 01:53:19,520
TELLING YOU, IT'S NOT VERY MUCH.

2800
01:53:19,520 --> 01:53:25,640
AND IT'S A B1 SELF-BOMBER THAT

2801
01:53:25,640 --> 01:53:27,360
COST $745 MILLION SO THAT IS IS

2802
01:53:27,360 --> 01:53:32,320
1010 OF THOSE TO FUND THE MEDICL

2803
01:53:32,320 --> 01:53:33,320
CANCER INSTITUTE.

2804
01:53:33,320 --> 01:53:33,560
I WILL

2805
01:53:33,560 --> 01:53:36,440
YOU A FEW BOMB

2806
01:53:36,440 --> 01:53:38,640
FEW BOMBERS, I WILL.

2807
01:53:38,640 --> 01:53:40,920
ANYONE WANT TO SUPPORT ME?

2808
01:53:40,920 --> 01:53:42,960
WE CAN TAKE A BIT OF THAT AND

2809
01:53:42,960 --> 01:53:44,480
APPLY IT TO CANCER IS.

2810
01:53:44,480 --> 01:53:46,280
MONICA, I WANT TO GIVE YOU A

2811
01:53:46,280 --> 01:53:47,480
CHANCE TO SAY ANYTHING.

2812
01:53:47,480 --> 01:53:48,920
I HAVEN'T ASKED YOU TO COMMENT

2813
01:53:48,920 --> 01:53:49,720
BECAUSE I KNOW YOU ARE

2814
01:53:49,720 --> 01:53:50,320
LISTENING.

2815
01:53:50,320 --> 01:53:51,280
ANY LAST WORDS?

2816
01:53:51,280 --> 01:53:56,080
>>WELL, I KNOW THAT TIME
IS

2817
01:53:56,080 --> 01:53:57,240
BRIEF.

2818
01:53:57,240 --> 01:54:01,320
LISTEN, I REALLY LOOK FORWARD TL

2819
01:54:01,320 --> 01:54:01,560
SESSION.

2820
01:54:01,560 --> 01:54:03,840
NOW I LOOK FORWARD IN THE VERY

2821
01:54:03,840 --> 01:54:06,440
NEAR FUTURE TO SOME REALLY

2822
01:54:06,440 --> 01:54:10,520
SUBSTANTIVE CONVERSATIONS AND

2823
01:54:10,520 --> 01:54:12,160
ENGAGEMENT WITH THIS GROUP OVER

2824
01:54:12,160 --> 01:54:13,160
EXACTLY THE ISSUES THAT I TALKED

2825
01:54:13,160 --> 01:54:13,840
ABOUT.

2826
01:54:13,840 --> 01:54:15,200
WHAT ARE OUR STRATEGIES?

2827
01:54:15,200 --> 01:54:16,960
WHAT ARE OUR APPROACHES?

2828
01:54:16,960 --> 01:54:20,720
WHAT IS IT REALLY TAKE?

2829
01:54:20,720 --> 01:54:23,320
WHO SHOULD BE DOING THE WORK?

2830
01:54:23,320 --> 01:54:24,880
WHO AND HOW SHOULD THE WORKING

2831
01:54:24,880 --> 01:54:25,360
DONE?

2832
01:54:25,360 --> 01:54:27,080
YOU KNOW, ALL OF THOSE THINGS,

2833
01:54:27,080 --> 01:54:29,440
IT'S ONE THING TO SAY LET'S

2834
01:54:29,440 --> 01:54:32,240
INCREASE THE R PG POLL.

2835
01:54:32,240 --> 01:54:35,760
THERE ARE SO MANY OTHER PLAYERS

2836
01:54:35,760 --> 01:54:38,080
OF NUANCE THAT HELP US ACHIEVE

2837
01:54:38,080 --> 01:54:42,160
THE SOCIETAL AIMS WE HAVE.

2838
01:54:42,160 --> 01:54:44,160
LECTOR JUST BROUGHT OUT A BIG

2839
01:54:44,160 --> 01:54:46,000
ONE THAT AREN'T JUST GOING TO

2840
01:54:46,000 --> 01:54:47,720
FLOAT OUT OF THE RPG POOL,

2841
01:54:47,720 --> 01:54:48,480
RIGHT.

2842
01:54:48,480 --> 01:54:49,800
SO IT'S STRATEGIZING TO

2843
01:54:49,800 --> 01:54:52,400
UNDERSTAND HOW TO MAKE PROGRESS

2844
01:54:52,400 --> 01:54:54,160
THERE THAT I RALLY LOOK FORWARD

2845
01:54:54,160 --> 01:54:56,320
TO WORKING WITH YOU TO DO AND I

2846
01:54:56,320 --> 01:54:57,400
THINK WE HAVE SOME IDEAS AND

2847
01:54:57,400 --> 01:54:59,760
WE'LL BE DISCUSSING HOW WE CAN

2848
01:54:59,760 --> 01:55:03,200
WORK TOGETHER SOON.

2849
01:55:03,200 --> 01:55:06,160
>>AND SEVERAL OF YOU HAVE
SENT

2850
01:55:06,160 --> 01:55:07,960
ME SOME IDEAS AND I'LL ACCEPTING

2851
01:55:07,960 --> 01:55:09,920
SOME OF THOSE ALONG TO Dr.

2852
01:55:09,920 --> 01:55:12,320
BERTAGNOLLI AND IF YOU HAVE

2853
01:55:12,320 --> 01:55:13,680
ADDITIONAL IDEAS, SEND THEM TO

2854
01:55:13,680 --> 01:55:15,440
ME AND WE'LL MAKE SURE THAT WE

2855
01:55:15,440 --> 01:55:18,840
GET THEM IN FRONT OF OUR NEW

2856
01:55:18,840 --> 01:55:20,480
DIRECTOR AND ON THAT NOTE, I

2857
01:55:20,480 --> 01:55:23,120
THINK WE'RE EXACTLY -- I'M

2858
01:55:23,120 --> 01:55:25,240
GIVING YOU BACK 30 SECONDS OR

2859
01:55:25,240 --> 01:55:27,000
SO.

2860
01:55:27,000 --> 01:55:29,040
SEE EVERYBODY NEXT TIME,

2861
01:55:29,040 --> 01:55:30,800
HOPEFULLY AND WE'LL HAVE AN IDEA

2862
01:55:30,800 --> 01:55:32,240
SESSION AND I'M GOING TO CHARGE

2863
01:55:32,240 --> 01:55:36,400
CHALLENGE YOU ALL TO COME WITH

2864
01:55:36,400 --> 01:55:36,720
YOUR IDEAS.

2865
01:55:36,720 --> 01:55:38,640
SEE YOU ON THE OTHER SIDE, HERE.

2866
01:55:38,640 --> 01:55:42,000
>>THE NCBA SUBCOMMITTEE

2867
01:55:42,000 --> 01:55:43,000
MEETINGS HAVE CONCLUDED AND WE

2868
01:55:43,000 --> 01:55:45,400
WILL TRANSLATE TO THE NCAB OPEN

2869
01:55:45,400 --> 01:55:46,240
SESSION THAT WILL BE AT 1:15.

2870
01:55:46,240 --> 01:55:47,520
>>THANK YOU, AGAIN,
KATHERINE.

2871
01:55:47,520 --> 01:56:03,040
>>THIS SESSION WILL NOW
END.