1
00:00:08,254 --> 00:00:10,356
>> LET ME WELCOME
EVERYONE.

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I ONLY HAVE 28 PARTICIPANTS ON

3
00:00:12,658 --> 00:00:15,728
MY SIDE.

4
00:00:15,728 --> 00:00:17,697
>> THAT'S OKAY, BECAUSE
SOME

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00:00:17,697 --> 00:00:20,433
PEOPLE ARE ON THE VIDEOCAST,

6
00:00:20,433 --> 00:00:21,834
SOME STAFF ARE ON THE VIDEOCAST

7
00:00:21,834 --> 00:00:23,469
SO IT'S COUNCIL AND ONLY A

8
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HANDFUL OF OTHER NIDA STAFF.

9
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>> OKAY.

10
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SO WITH THAT, I'M THEN GOING TO

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WELCOME EVERYONE TO THE 146TH

12
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MEETING OF THE NATIONAL ADVISORY

13
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COUNCIL ON DRUG ABUSE.

14
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IT A PLEASURE TO HAVE YOU HERE

15
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AND WE ALWAYS LOOK FORWARD TO

16
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HEARING YOUR COMMENTS AND GIVE

17
00:00:40,219 --> 00:00:42,388
YOU AN UPDATE OF SOME OF THE

18
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MAIN ISSUES THAT WE ARE DEALING

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WITH AS AN INSTITUTE, AND THE

20
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SCIENCE THAT'S EMERGING.

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WITH THAT, I'M GOING TO START

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FORMALLY THE MEETING AND I'M

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READING THE GOVERNMENT -- ACT

24
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REQUIRE THAT AS MANY ADVISORY

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COMMITTEE MEETINGS AS POSSIBLE

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00:01:01,073 --> 00:01:02,775
BE OPEN TO THE PUBLIC.

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THIS INCLUDES MEETINGS OF THE

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NATIONAL ADVISORY COUNCIL ON

29
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DRUG ABUSE.

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TODAY'S MEETING IS OPEN TO THE

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PUBLIC AND IS VIDEOCAST AND

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RECORDED.

33
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MINUTES OF THE MEETING WILL BE

34
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AVAILABLE ON THE NIDA HOME PAGE,

35
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RECORDINGS OF THE OPEN COUNCIL

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MEETINGS ARE POSTED ON THE NIH

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VIDEOCAST SITE.

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MEMBERS OF THE PUBLIC WHO MAY

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WISH TO EXPRESS VIEWS REGARDING

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ANY ITEM DISCUSSED DURING THIS

41
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MEETING MAY DO SO BY WRITING DR,

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WITHIN 10 DAYS OF THE MEETING.

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ANY WRITTEN STATEMENTS BY

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00:01:38,778 --> 00:01:39,779
MEMBERS OF THE PUBLIC WILL

45
00:01:39,779 --> 00:01:42,715
RECEIVE CAREFUL CONSIDERATIONS.

46
00:01:42,715 --> 00:01:45,584
AT THIS POINT, I'M GOING TO ASK

47
00:01:45,584 --> 00:01:47,353
FOR COMMENTS OR CORRECTIONS FOR

48
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MINUTES TO THE SEPTEMBER 23RD,

49
00:01:50,456 --> 00:01:50,923
2023 MEETING.

50
00:01:50,923 --> 00:01:54,193
A COPY OF THE MEETINGS WERE MADE

51
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AVAILABLE ON THE ELECTRONIC

52
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COUNCIL BOOK UNDER THE NIDA

53
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CURRENT COUNCIL.

54
00:01:57,196 --> 00:02:03,202
I WANT TO ASK FOR A VOTE ON OUR

55
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COUNCIL MEETINGS, I'LL ASK FOR A

56
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MOTION FOR APPROVAL.

57
00:02:06,372 --> 00:02:09,308
MOTION FOR APPROVAL.

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SECOND?

59
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ALL IN FAVOR?

60
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MOTION IS CARRIED.

61
00:02:15,081 --> 00:02:16,515
NOW I'M GOING TO ANNOUNCE THE

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FUTURE COUNCIL DATES.

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00:02:20,453 --> 00:02:22,855
THE NEXT ONE WILL BE ON

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MAY 7 AND 8, AND THAT'S BOTH OUR

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COUNCIL WHICH IS DONE JOINTLY

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WITH THE NIAA.

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SEPTEMBER 11 AND ON FEBRUARY 4,

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2025.

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00:02:37,069 --> 00:02:39,038
THAT'S ALL OF THE ITEMS THAT ARE

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PRESENT BEFORE I GIVE YOU MY

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00:02:41,607 --> 00:02:43,509
DIRECTOR'S REPORT.

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SO ANYTHING ELSE, SUSAN, OR

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SHOULD I JUMP IN?

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>> JUMP IN.

75
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>> OKAY, I'M JUMPING IN.

76
00:02:52,852 --> 00:02:58,758
LET ME SHARE MY SLIDES.

77
00:02:58,758 --> 00:03:00,192
AND I'LL NEED TO KNOW IF YOU'RE

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SEEING THEM.

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IS THAT OKAY?

80
00:03:09,335 --> 00:03:10,069
>> PERFECT.

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00:03:10,069 --> 00:03:11,871
>> WELL, FIRST OF ALL,
AGAIN, I

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WANT TO REITERATE THAT IT'S A

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PLEASURE TO BE ABLE TO PRESENT

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00:03:16,041 --> 00:03:17,543
TO YOU, AND WHAT I'M GOING TO DO

85
00:03:17,543 --> 00:03:18,544
IS, OF COURSE, HIGHLIGHT SOME OF

86
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THE ISSUES THAT ARE MOST SALIENT

87
00:03:22,047 --> 00:03:23,883
AND THAT ARE DRIVING MANY OF THE

88
00:03:23,883 --> 00:03:28,954
PRIORITIES IN TERMS OF RESEARCH.

89
00:03:28,954 --> 00:03:30,055
EXTREMELY IMPORTANT, I'M SURE

90
00:03:30,055 --> 00:03:31,457
THAT MOST OF YOU KNOW BUT WE

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00:03:31,457 --> 00:03:36,162
HAVE A NEW DIRECTOR OF THE NIH,

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00:03:36,162 --> 00:03:37,596
DR. MONICA BERTAGNOLLI, AND

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SHE'S THE SECOND WOMAN TO TAKE

94
00:03:38,898 --> 00:03:41,434
THAT POSITION AT THE NIH.

95
00:03:41,434 --> 00:03:43,502
SHE WAS NOMINATED BY PRESIDENT

96
00:03:43,502 --> 00:03:45,905
JOE BIDEN ON MAY 15TH, AND

97
00:03:45,905 --> 00:03:47,773
CONFIRMED BY THE SENATE ON

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00:03:47,773 --> 00:03:49,508
NOVEMBER 7 OF LAST YEAR, AND SHE

99
00:03:49,508 --> 00:03:51,277
TOOK OFFICE TWO DAYS LATER.

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00:03:51,277 --> 00:03:54,346
SHE'S THE FIRST SURGEON AND AS I

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00:03:54,346 --> 00:03:55,648
SAY, THE SECOND WOMAN TO HOLD

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THE POSITION OF DIRECTOR OF THE

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NIH.

104
00:03:59,251 --> 00:04:00,719
SHE'S A LEADER IN CLINICAL

105
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ONCOLOGY AND HER RESEARCH HAS

106
00:04:02,321 --> 00:04:04,824
FOCUSED ON GENETIC DRIVERS OF

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00:04:04,824 --> 00:04:05,324
GASTROINTESTINAL CANCER

108
00:04:05,324 --> 00:04:06,358
DEVELOPMENT AND THE ROLE OF

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00:04:06,358 --> 00:04:08,761
INFLAMMATION ON CANCER DRUG.

110
00:04:08,761 --> 00:04:10,296
SHE HAS LED TRANSLATIONAL

111
00:04:10,296 --> 00:04:12,698
SCIENCE INITIATIVES IN THE NCI

112
00:04:12,698 --> 00:04:15,434
FUNDED COOPERATIVE GROUPS

113
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PROGRAM, WHICH IS THE NCI'S

114
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EQUIVALENT OF THE NATIONAL

115
00:04:18,204 --> 00:04:19,905
CLINICAL TRIALS NETWORK FROM

116
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1994 TO 2011.

117
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SHE'S GROUP CHAIR OF THE

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ALLIANCE FOR CLINICAL TRIALS IN

119
00:04:26,512 --> 00:04:27,913
ONCOLOGY, AND NATIONAL CLINICAL

120
00:04:27,913 --> 00:04:29,982
TRIALS NETWORK MEMBER

121
00:04:29,982 --> 00:04:34,153
ORGANIZATION FROM 2011 TO 2022.

122
00:04:34,153 --> 00:04:38,157
AND SHE IS CHIEF OF THE DIVISION

123
00:04:38,157 --> 00:04:40,059
OF SURGICAL ONCOLOGY FOR DANA

124
00:04:40,059 --> 00:04:42,261
FARBER BRIGHAM CANCER CENTER

125
00:04:42,261 --> 00:04:43,362
FROM 2007 TO 2018.

126
00:04:43,362 --> 00:04:44,997
SO SHE HAS HAD A SPECTACULAR

127
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CAREER WITH VERY, VERY STRONG --

128
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VERY STRONG IN CLINICAL

129
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SCIENCES.

130
00:04:50,903 --> 00:04:52,738
BUT ALSO IN BASIC COMPONENTS OF

131
00:04:52,738 --> 00:04:56,141
CANCER DEVELOPMENT.

132
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AND I WANTED TO HIGHLIGHT SOME

133
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OF THE POINTS THAT SHE HAS SAID

134
00:04:59,111 --> 00:05:01,614
BECAUSE I DO THINK THAT IT DOES

135
00:05:01,614 --> 00:05:02,581
REFLECT VERY MUCH WHERE SOME OF

136
00:05:02,581 --> 00:05:04,783
THE PRIORITIES AT THE WHOLE

137
00:05:04,783 --> 00:05:07,086
LEVEL OF THE NIH ARE GOING TO BE

138
00:05:07,086 --> 00:05:08,621
HAPPENING, WHICH ARE ALSO

139
00:05:08,621 --> 00:05:10,456
EXTREMELY TIMELY AND CONSISTENT

140
00:05:10,456 --> 00:05:13,225
WITH MANY OF THE INITIATIVES AT

141
00:05:13,225 --> 00:05:13,526
NIDA.

142
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SO I'M GOING TO QUOTE FROM SOME

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OF THE THINGS THAT SHE HAS

144
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BASICALLY EXPRESSED.

145
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OUR WORK IS NOT FINISHED WHEN WE

146
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DELIVER SCIENTIFIC DISCOVERIES.

147
00:05:21,634 --> 00:05:23,836
OUR WORK IS FINISHED WHEN PEOPLE

148
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ARE LIVING LONG AND HEALTHY

149
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LIVES.

150
00:05:27,973 --> 00:05:29,708
NIH RESEARCH ENCOMPASSES THE

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LABORATORY, THE CLINIC, AND THE

152
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COMMUNITY.

153
00:05:33,212 --> 00:05:34,747
PATIENTS ARE PARTNERS IN

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DISCOVERY.

155
00:05:36,649 --> 00:05:37,950
NIH AIMS TO BRING MORE MEMBERS

156
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OF THE PUBLIC INTO THE RESEARCH

157
00:05:40,319 --> 00:05:41,954
ENTERPRISE AS PARTNERS IN

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DISCOVERY.

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00:05:43,689 --> 00:05:46,025
INCOME, AGE, RACE, ETHNICITY,

160
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GEOGRAPHIC LOCATION, AND

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00:05:47,426 --> 00:05:49,628
DISABILITY STATUS SHOULD NOT BE

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BARRIERS TO PARTICIPATING IN

163
00:05:50,930 --> 00:05:53,032
RESEARCH OR BENEFITING FROM

164
00:05:53,032 --> 00:05:55,200
RESEARCH ADVANCES.

165
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PROGRESS IS ACCELERATED WHEN

166
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ADVANCED SCIENTIFIC METHODS ARE

167
00:05:58,804 --> 00:06:00,906
APPLIED TO DATA THAT INCLUDES

168
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EVERYONE, AND WHEN NEW

169
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DISCOVERIES ARE RAPIDLY -- SOR 

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SORRY -- AND WHEN NEW

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DISCOVERIES ARE RAPIDLY AND

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EQUITILY DELIVEEQUITABLY DELI AL

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CARE.

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YOU CAN SEE WHY THERE IS SO MUCH

175
00:06:31,437 --> 00:06:33,038
EXCITEMENT AMONG THE VARIOUS

176
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INSTITUTE DIRECTORS AND STAFF AT

177
00:06:35,574 --> 00:06:36,775
THE NIH ARE BRINGING SOMEONE

178
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THAT IS SO INCREDIBLY INCLUSIVE

179
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AND SO COMMITTED TO ADVANCING

180
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TRANSLATION AND BRING SOLUTIONS

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SO THAT PEOPLE'S LIVES ARE

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BETTER.

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ANOTHER IMPORTANT ADVANCE THAT

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00:06:49,688 --> 00:06:52,424
HAS HAPPENED IS THE NIH FELLOWS

185
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UNITED.

186
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ON DECEMBER 7 OF LAST YEAR, A

187
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MAJORITY OF THE VOTING NIH

188
00:06:58,430 --> 00:07:01,066
FELLOWS UNITED VOTED TO BE

189
00:07:01,066 --> 00:07:02,201
REPRESENTED BY THE INTERNATIONAL

190
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UNION OF UNITED AUTOMOBILE,

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AEROSPACE AND AGRICULTURAL

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00:07:06,639 --> 00:07:10,476
IMPLEMENT WORKERS OF AMERICA.

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THE FEDERAL LABOR RELATIONS

194
00:07:12,444 --> 00:07:13,512
AUTHORITY CERTIFIED THE

195
00:07:13,512 --> 00:07:16,582
BARGAINING UNIT ON DECEMBER 15,

196
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2023.

197
00:07:17,016 --> 00:07:20,419
AND THE UAW UNIT COVERS

198
00:07:20,419 --> 00:07:24,890
APPROXIMATELY 5,000 NIH FELLOWS.

199
00:07:24,890 --> 00:07:27,760
NIH WILL PARTNER WITH THE UAW TO

200
00:07:27,760 --> 00:07:29,795
NEGOTIATE A COLLECTIVE

201
00:07:29,795 --> 00:07:31,697
BARGAINING AGREEMENT FOR THE

202
00:07:31,697 --> 00:07:32,464
PARTIES.

203
00:07:32,464 --> 00:07:33,165
COLLECTIVE BARGAINING WILL BE

204
00:07:33,165 --> 00:07:34,633
ONGOING THROUGHOUT 2024.

205
00:07:34,633 --> 00:07:38,370
AND WE WILL BE UPDATING YOU AS

206
00:07:38,370 --> 00:07:41,106
DECISIONS ARE MADE.

207
00:07:41,106 --> 00:07:42,875
WITH RESPECT TO THE BUDGET, WE

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00:07:42,875 --> 00:07:44,610
ARE CURRENTLY ON A CONTINUING

209
00:07:44,610 --> 00:07:48,547
RESOLUTION THAT BASICALLY MEANS

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VERY LIKELY FLAT BUDGETS FOR

211
00:07:50,683 --> 00:07:53,252
2025 AND PERHAPS FOR -- WE DON'T

212
00:07:53,252 --> 00:07:55,320
KNOW WHAT WILL HAPPEN IN 2026,

213
00:07:55,320 --> 00:07:57,189
BUT THERE IS A POSSIBILITY THAT

214
00:07:57,189 --> 00:08:00,159
THERE WOULD ALSO BE FLAT

215
00:08:00,159 --> 00:08:01,460
BUDGETS, CONSIDERING THAT THE

216
00:08:01,460 --> 00:08:05,731
COST OF DOING RESEARCH IS

217
00:08:05,731 --> 00:08:06,965
INCREASING, EVEN THOUGH IT'S

218
00:08:06,965 --> 00:08:09,001
SAME BUDGETS AS BEFORE, ACTUALLY

219
00:08:09,001 --> 00:08:12,604
MEANS A DECREASE IN THE BUYING

220
00:08:12,604 --> 00:08:16,975
POWER THAT THOSE DOLLARS IS.

221
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WE ARE AWARE OF THIS, WE ARE

222
00:08:18,844 --> 00:08:21,680
HOPEFUL THAT THERE WILL NOT BE

223
00:08:21,680 --> 00:08:23,982
DRASTIC CUTS BEYOND THOSE THAT

224
00:08:23,982 --> 00:08:27,252
MAY BE INFLICTED IF WE DO GET A

225
00:08:27,252 --> 00:08:27,920
CONTINUING RESOLUTION AND IT'S

226
00:08:27,920 --> 00:08:29,354
NOT RESOLVED.

227
00:08:29,354 --> 00:08:31,423
AND SO WE'RE WORKING WITH THE

228
00:08:31,423 --> 00:08:35,461
POSSIBILITY OF A FLAT BUDGET.

229
00:08:35,461 --> 00:08:38,530
BECAUSE OF THE -- AS I WAS

230
00:08:38,530 --> 00:08:40,399
MENTIONING THE INCREASES IN COST

231
00:08:40,399 --> 00:08:43,569
AND IT IS -- THIS IS GOING TO

232
00:08:43,569 --> 00:08:45,104
RESULT IN A SLOWING OF NEW

233
00:08:45,104 --> 00:08:47,172
DISCOVERIES.

234
00:08:47,172 --> 00:08:49,374
IT WILL -- THERE IS CONCERN THAT

235
00:08:49,374 --> 00:08:53,412
IF THE FUNDS ARE LESS, THIS WILL

236
00:08:53,412 --> 00:08:54,480
ACTUALLY DETRACT OUR YOUNG

237
00:08:54,480 --> 00:08:56,048
INVESTIGATORS TO GO INTO SCIENCE

238
00:08:56,048 --> 00:08:58,817
CAREERS, AND WE MAY LOSE THEM,

239
00:08:58,817 --> 00:09:00,285
AND PARTICULARLY VULNERABLE IS

240
00:09:00,285 --> 00:09:02,488
THAT OUR INTRAMURAL RESEARCH

241
00:09:02,488 --> 00:09:06,759
PROGRAMS AT THE NIH, BECAUSE

242
00:09:06,759 --> 00:09:08,627
BASICALLY MOST OF THE FUNDS GO

243
00:09:08,627 --> 00:09:11,797
INTO PERSONNEL AND THEY CANNOT

244
00:09:11,797 --> 00:09:15,067
BALANCE BY GOING OUT AND BEING

245
00:09:15,067 --> 00:09:17,803
ABLE TO GET ADDITIONAL FUNDING.

246
00:09:17,803 --> 00:09:19,538
SO THAT MAKES IT -- THAT'S WHAT

247
00:09:19,538 --> 00:09:21,573
MAKES THE INTRAMURAL PROGRAM SO

248
00:09:21,573 --> 00:09:24,042
PARTICUPARTICULARLY SENSITIVE TE

249
00:09:24,042 --> 00:09:29,181
SITUATIONS WHERE THE NIH -- ARE

250
00:09:29,181 --> 00:09:29,681
CUT.

251
00:09:29,681 --> 00:09:31,049
SO IN THIS LANDSCAPE, WE HAVE TO

252
00:09:31,049 --> 00:09:32,518
BE VERY AWARE THAT IN ORDER TO

253
00:09:32,518 --> 00:09:33,752
ADVANCE THE SCIENCE, WHICH IS

254
00:09:33,752 --> 00:09:36,622
OUR RESPONSIBILITY, WE NEED TO

255
00:09:36,622 --> 00:09:38,490
ALSO MAXIMIZE AND BE STRATEGIC

256
00:09:38,490 --> 00:09:41,627
AND CREATE PARTNERSHIPS THAT CAN

257
00:09:41,627 --> 00:09:46,565
HELP US DO RESEARCH.

258
00:09:46,565 --> 00:09:47,166
, BECAUSE IT

259
00:09:47,166 --> 00:09:52,805
IS URGENTLY NEEDED.

260
00:09:52,805 --> 00:09:54,239
I WANT TO ALSO HIGHLIGHT OF SOME

261
00:09:54,239 --> 00:09:56,308
VERY, VERY EXCITING ADVANCES

262
00:09:56,308 --> 00:09:58,043
FROM BRAIN, AND THIS WAS LAST

263
00:09:58,043 --> 00:10:01,380
YEAR, THERE WAS A WHOLE VOLUME

264
00:10:01,380 --> 00:10:05,951
OF THE JOURNAL NATURE DEVOTED TO

265
00:10:05,951 --> 00:10:08,887
THE CHARACTERIZATION OF THE

266
00:10:08,887 --> 00:10:11,523
COMPLETE MULTIMODAL CELL CENSUS

267
00:10:11,523 --> 00:10:13,926
OF THE MOUSE BRAIN, AND THIS IS

268
00:10:13,926 --> 00:10:15,761
A PRODUCT OF THE BRAIN

269
00:10:15,761 --> 00:10:17,996
INITIATIVE CELL CENSUS NETWORK,

270
00:10:17,996 --> 00:10:20,799
AND IT'S VERY, VERY EXCITING

271
00:10:20,799 --> 00:10:24,636
BECAUSE IT NOW PROVIDES US AN

272
00:10:24,636 --> 00:10:28,240
INSIDE DIVERSITY OF CELLS IN THE

273
00:10:28,240 --> 00:10:29,541
BRAIN, AND WAY BEYOND WHAT WE

274
00:10:29,541 --> 00:10:33,212
HAD EVER THOUGHT, AND THROUGH

275
00:10:33,212 --> 00:10:34,046
TOOLS THAT AT THE SAME TIME IN

276
00:10:34,046 --> 00:10:35,113
PARALLEL ARE BEING DEVELOPED BY

277
00:10:35,113 --> 00:10:39,084
THE BRAIN INITIATIVE, WE NOW

278
00:10:39,084 --> 00:10:41,053
HAVE THE FEASIBILITY OF

279
00:10:41,053 --> 00:10:44,223
POTENTIALLY MANIPULATING

280
00:10:44,223 --> 00:10:46,525
SPECIFIC CELLS AND UNDERSTANDING

281
00:10:46,525 --> 00:10:50,362
THEIR EFFECTS.

282
00:10:50,362 --> 00:10:52,030
AND WITH THAT, I DO WAS TO ALSO

283
00:10:52,030 --> 00:10:53,198
ALERT YOU AND INVITE YOU TO

284
00:10:53,198 --> 00:10:54,700
ATTEND THE ANIMAL BRAIN

285
00:10:54,700 --> 00:10:55,601
INITIATIVE CONFERENCE, WHICH

286
00:10:55,601 --> 00:10:58,871
WILL TAKE PLACE ON JUNE 17 AND

287
00:10:58,871 --> 00:11:00,839
JUNE 18, AND WHERE YOU WILL HEAR

288
00:11:00,839 --> 00:11:02,474
SOME OF THE MOST EXCITING

289
00:11:02,474 --> 00:11:04,443
ADVANCES THAT HAVE COME OUT OF

290
00:11:04,443 --> 00:11:08,046
THE BRAIN, WHICH INCLUDE TOOLS

291
00:11:08,046 --> 00:11:10,916
BUT ALSO UTILIZATION AND

292
00:11:10,916 --> 00:11:13,986
EXAMPLES ABOUT HOW THESE TOOLS

293
00:11:13,986 --> 00:11:15,287
ARE ILLUMINATING OUR

294
00:11:15,287 --> 00:11:18,657
UNDERSTANDING OF HOW THE BRAIN

295
00:11:18,657 --> 00:11:21,193
OF RODENTS, NON-HUMAN PRIMATES

296
00:11:21,193 --> 00:11:25,564
AND HUMANS ACTUALLY IS ORGANI

297
00:11:25,564 --> 00:11:25,831
ORGANIZED.

298
00:11:25,831 --> 00:11:26,965
SO THERE IS THE CELL CENSUS BUT

299
00:11:26,965 --> 00:11:29,334
THERE IS ALSO THE VERY DETAILED

300
00:11:29,334 --> 00:11:30,702
CHARACTERIZATION OF THE

301
00:11:30,702 --> 00:11:33,538
CONNECTIONS BETWEEN CELLS AND

302
00:11:33,538 --> 00:11:35,507
BETWEEN MULTIPLE CELL AREAS INTO

303
00:11:35,507 --> 00:11:37,809
NETWORKS AND HOW THEN THESE

304
00:11:37,809 --> 00:11:39,244
ULTIMATELY TRANSLATES INTO

305
00:11:39,244 --> 00:11:41,613
BEHAVIOR.

306
00:11:41,613 --> 00:11:43,081
SO EXTRAORDINARILY EXCITING.

307
00:11:43,081 --> 00:11:50,756
SO IF YOU ARE ABLE TO JOIN, YOU

308
00:11:50,756 --> 00:11:52,691
WILL NOT BE DISAPPOINTED.

309
00:11:52,691 --> 00:11:54,326
NOW I WANT TO JUMP INTO NIDA

310
00:11:54,326 --> 00:11:55,093
ITSELF.

311
00:11:55,093 --> 00:11:56,862
I ALWAYS START BY DESCRIBING OUR

312
00:11:56,862 --> 00:11:57,396
BUDGET.

313
00:11:57,396 --> 00:11:59,665
SO HERE ARE THE BUDGETS FOR 2023

314
00:11:59,665 --> 00:12:05,537
AND THE BUDGETS FOR 2024 AND FOR

315
00:12:05,537 --> 00:12:05,904
THE PRESIDENT'S.

316
00:12:05,904 --> 00:12:06,972
THIS IS BASICALLY BECAUSE WE ARE

317
00:12:06,972 --> 00:12:09,107
ON A CONTINUING RESOLUTION, OUR

318
00:12:09,107 --> 00:12:11,209
BUDGETS ARE BASED ON WHAT WE

319
00:12:11,209 --> 00:12:15,447
GOTTEN ACTED IN 2023, AND YOU'RE

320
00:12:15,447 --> 00:12:16,615
SEEING I'VE BEEN PRESENTING THE

321
00:12:16,615 --> 00:12:21,153
BUDGETS AS THE BASE AND DIVIDING

322
00:12:21,153 --> 00:12:22,421
THE BASE SEPARATE FROM THE HILL,

323
00:12:22,421 --> 00:12:23,922
AND THE REASON WHY THIS IS FOR

324
00:12:23,922 --> 00:12:27,259
IS THAT THE HEAL FUNDS WERE

325
00:12:27,259 --> 00:12:31,530
ALLOCATED TO NIDA, AND AN

326
00:12:31,530 --> 00:12:33,932
EQUIVALENT WAS ALLOCATED TO

327
00:12:33,932 --> 00:12:35,600
NINDS, SPECIFICALLY TO ADVANCE

328
00:12:35,600 --> 00:12:36,435
SCIENCE AND KNOWLEDGE THAT WOULD

329
00:12:36,435 --> 00:12:39,171
HELP US ADDRESS THE OVERDOSE

330
00:12:39,171 --> 00:12:40,739
CRISIS.

331
00:12:40,739 --> 00:12:42,574
SO BY PLACING THEM AS A SEPARATE

332
00:12:42,574 --> 00:12:45,444
CATEGORY, IT DOES HIGHLIGHT THE

333
00:12:45,444 --> 00:12:49,281
URGENCY THAT WE -- OF BASICALLY

334
00:12:49,281 --> 00:12:50,682
WHERE WE ARE AND HOW WE WANT TO

335
00:12:50,682 --> 00:12:52,851
USE THOSE FUNDS TO HELP US

336
00:12:52,851 --> 00:12:56,254
ADDRESS THESE OVERWHELMING AND

337
00:12:56,254 --> 00:12:57,789
TRAGIC LOSS OF LIVES FROM THE

338
00:12:57,789 --> 00:12:59,858
OVERDOSE CRISIS.

339
00:12:59,858 --> 00:13:08,066
SO FROM 2022 TO 2023, WE DID GET

340
00:13:08,066 --> 00:13:10,202
AN INCREASE OF FUNDS AND WE GOT

341
00:13:10,202 --> 00:13:11,236
$10 MILLION EXTRA FOR HEAL, AND

342
00:13:11,236 --> 00:13:13,405
WE ALSO GOT -- THE INSTITUTE

343
00:13:13,405 --> 00:13:22,280
ALSO GOT $10 MILLION FOR PAIN.

344
00:13:22,280 --> 00:13:23,582
IN TERMS OF THE INSTITUTE

345
00:13:23,582 --> 00:13:24,916
ITSELF, I AM REALLY, REALLY

346
00:13:24,916 --> 00:13:27,519
EXCITED TO MAKE THE ANNOUNCEMENT

347
00:13:27,519 --> 00:13:30,589
THAT DR. IVAN MONTOYA HAS BEEN

348
00:13:30,589 --> 00:13:33,525
OFFERED AND ACCEPTED THE

349
00:13:33,525 --> 00:13:36,061
POSITION OF DIVISION OF

350
00:13:36,061 --> 00:13:36,828
THERAPEUTICS AT NIDA.

351
00:13:36,828 --> 00:13:38,530
MOST OF YOU KNOW HIM BECAUSE

352
00:13:38,530 --> 00:13:39,564
IVAN HAS BEEN THE ACTING

353
00:13:39,564 --> 00:13:43,702
DIRECTOR FOR THE DTMC FOR MORE

354
00:13:43,702 --> 00:13:45,837
THAN A YEAR, AND BEFORE THAT, HE

355
00:13:45,837 --> 00:13:50,375
HAS BEEN THE DEPUTY DIRECTOR FOR

356
00:13:50,375 --> 00:13:51,276
A LONG, LONG TIME.

357
00:13:51,276 --> 00:13:53,745
SO HE HAS A STRONG, STRONG

358
00:13:53,745 --> 00:13:56,848
KNOWLEDGE ABOUT THE PROCESS OF

359
00:13:56,848 --> 00:13:58,650
THE DEVELOPMENT OF MEDICATIONS

360
00:13:58,650 --> 00:14:00,786
AND ALSO VERY KNOWLEDGEABLE

361
00:14:00,786 --> 00:14:06,358
ABOUT HOW THE NIH WORKS AND THE

362
00:14:06,358 --> 00:14:07,359
INTERACTIONS -- AND HIS

363
00:14:07,359 --> 00:14:09,428
INTERACTIONS WITH THE OTHER

364
00:14:09,428 --> 00:14:10,495
DIVISIONS AND HIS OFFICE HAS

365
00:14:10,495 --> 00:14:11,963
BEEN VERY, VERY PRODUCTIVE, AS

366
00:14:11,963 --> 00:14:14,433
WELL AS HIS INTERACTIONS WITH

367
00:14:14,433 --> 00:14:15,434
THE PHARMACEUTICAL INDUSTRY.

368
00:14:15,434 --> 00:14:16,968
SO IT'S A PLEASURE, WE ARE

369
00:14:16,968 --> 00:14:19,604
REALLY DELIGHTED THAT IVAN HAS

370
00:14:19,604 --> 00:14:21,440
AGREED TO DO THIS -- TAKE ON THE

371
00:14:21,440 --> 00:14:23,175
ROLE OF DIRECTOR OF THAT

372
00:14:23,175 --> 00:14:24,109
DIVISION OF THERAPEUTICS.

373
00:14:24,109 --> 00:14:26,578
AND WE LOOK FORWARD TO MANY

374
00:14:26,578 --> 00:14:30,082
DISCOVERIES.

375
00:14:30,082 --> 00:14:32,484
I ALSO WRANT TO ANNOUNCE TOO

376
00:14:32,484 --> 00:14:35,220
THAT MR. MICHELE RANKIN WILL

377
00:14:35,220 --> 00:14:37,255
ALSO BE THE DIRECTOR FOR OF

378
00:14:37,255 --> 00:14:38,523
OFFICE OF NIDA HEAL.

379
00:14:38,523 --> 00:14:41,893
THIS RESULTED AS -- WHEN IT USED

380
00:14:41,893 --> 00:14:44,463
TO BE THAT HEAL WAS DIRECTED

381
00:14:44,463 --> 00:14:45,764
FROM THE OFFICE OF THE DIRECTOR

382
00:14:45,764 --> 00:14:49,835
OF THE NIH AT THE BEGINNING WITH

383
00:14:49,835 --> 00:14:52,304
THE PURPOSE AND THE MISSION TO

384
00:14:52,304 --> 00:14:54,706
TRY TO STABILIZE THE FUNDING AND

385
00:14:54,706 --> 00:14:56,575
TO CREATE A THROUGHPUT AND,

386
00:14:56,575 --> 00:15:00,378
AGAIN, THAT WILL THEN ULTIMATELY

387
00:15:00,378 --> 00:15:01,546
ENSURE THAT THERE WAS ADVANCES

388
00:15:01,546 --> 00:15:06,284
IN THE FIELD OF OPIOID USE

389
00:15:06,284 --> 00:15:07,519
DISORDER AND OVERDOSE PREVENTION

390
00:15:07,519 --> 00:15:08,887
AND TREATMENT, WHILE AT THE SAME

391
00:15:08,887 --> 00:15:10,355
TIME ENSURING THAT THERE WAS

392
00:15:10,355 --> 00:15:11,756
INTEGRATION FOR RESEARCH THAT

393
00:15:11,756 --> 00:15:18,230
PERTAINED TO PAIN, AND SO NOW

394
00:15:18,230 --> 00:15:19,464
LAST YEAR IT MOVED FROM THE

395
00:15:19,464 --> 00:15:22,534
OFFICE OF THE DIRECTOR INTO THE

396
00:15:22,534 --> 00:15:24,569
TWO INSTITUTES THAT HAVE BEEN

397
00:15:24,569 --> 00:15:27,172
ASSIGNED RESOURCES, NIDA BEING

398
00:15:27,172 --> 00:15:28,440
ONE OF THEM AND THE OTHER ONE

399
00:15:28,440 --> 00:15:29,875
NINDS.

400
00:15:29,875 --> 00:15:33,645
SO DR. MICHELE RANKIN WILL BE

401
00:15:33,645 --> 00:15:37,482
OUR LEAD AT NIDA FOR OVERSEEING

402
00:15:37,482 --> 00:15:39,818
THE RESOURCES THAT ARE PLACED IN

403
00:15:39,818 --> 00:15:41,953
ORDER TO ADVANCE THE SCIENCE FOR

404
00:15:41,953 --> 00:15:45,357
HEAL.

405
00:15:45,357 --> 00:15:47,626
AND MICHELLE HAS BEEN DOING

406
00:15:47,626 --> 00:15:49,161
REALLY THAT ROLE, OVERSEEING AND

407
00:15:49,161 --> 00:15:49,828
ENSURING THAT ALL OF THE

408
00:15:49,828 --> 00:15:51,563
PROJECTS THAT ARE BEING FUNDED

409
00:15:51,563 --> 00:15:56,101
WITH HEAL DOLLARS ARE ACTUALLY

410
00:15:56,101 --> 00:16:00,405
REACHING THEIR GOALS.

411
00:16:00,405 --> 00:16:01,740
NOW LET ME JUMP INTO THE SCIENCE

412
00:16:01,740 --> 00:16:02,908
AND GET YOU AN UPDATE.

413
00:16:02,908 --> 00:16:04,776
SO THIS IS A SLIDE THAT I

414
00:16:04,776 --> 00:16:06,611
ACTUALLY BROUGHT TOGETHER FROM

415
00:16:06,611 --> 00:16:08,180
THE MONITORING THE FUTURE THAT,

416
00:16:08,180 --> 00:16:10,916
AS YOU KNOW, IS A SURVEY DONE,

417
00:16:10,916 --> 00:16:12,551
WE DO WHERE WE'RE ACTUALLY

418
00:16:12,551 --> 00:16:16,254
EVALUATING ON A YEARLY BASIS

419
00:16:16,254 --> 00:16:19,324
TEENAGERS THAT ARE IN 8TH, 10TH

420
00:16:19,324 --> 00:16:20,625
AND 12TH GRADE TO ASSESS THE

421
00:16:20,625 --> 00:16:21,626
PREVALENCE OF DRUG USE AS WELL

422
00:16:21,626 --> 00:16:22,827
AS THEIR ATTITUDES.

423
00:16:22,827 --> 00:16:26,097
AND THIS JUST SUMMARIZES IT,

424
00:16:26,097 --> 00:16:28,900
BECAUSE AS HAS BEEN THE CASE FOR

425
00:16:28,900 --> 00:16:31,903
2022 AND 2021, WE HAVE SEEN A

426
00:16:31,903 --> 00:16:33,538
VERY SIGNIFICANT REDUCTION IN

427
00:16:33,538 --> 00:16:37,576
THE USE OF DRUGS IN OUR COUNTRY

428
00:16:37,576 --> 00:16:38,810
AMONG TEENAGERS.

429
00:16:38,810 --> 00:16:40,011
ACTUALLY HAS BEEN MORE THAN

430
00:16:40,011 --> 00:16:43,181
2021, IT HAS BEEN JUST GOING

431
00:16:43,181 --> 00:16:51,489
DOWNWARD NOW FOR I WOULD SAY --

432
00:16:51,489 --> 00:16:57,596
WITH THE COVID PANDEMIC WE SAW A

433
00:16:57,596 --> 00:16:58,663
DRASTIC DECREASE IN DRUG USE

434
00:16:58,663 --> 00:16:59,998
WHICH WE WERE EXCITED ABOUT

435
00:16:59,998 --> 00:17:01,199
BECAUSE IN GENERAL, WE KNOW ONE

436
00:17:01,199 --> 00:17:02,534
OF THE MOST DANGEROUS PERIODS

437
00:17:02,534 --> 00:17:05,203
FOR DRUG EXPOSURES IS DURING ADD

438
00:17:05,203 --> 00:17:06,238
ADOLESCENCE, AND IT'S ALSO A

439
00:17:06,238 --> 00:17:08,440
PERIOD WHERE THEY'RE MORE LIKELY

440
00:17:08,440 --> 00:17:13,912
TO BE ENTICED INTO TAKING DRUGS.

441
00:17:13,912 --> 00:17:15,247
SO TO SEE SUCH A SIGNIFICANT

442
00:17:15,247 --> 00:17:17,382
CHANGE IN 2020, WHICH WE

443
00:17:17,382 --> 00:17:18,617
ACTUALLY ASCRIBE TO THE FACT

444
00:17:18,617 --> 00:17:20,385
THAT TEENAGERS WERE NO LONGER

445
00:17:20,385 --> 00:17:23,755
ABLE TO BE IN PLACES TOGETHER,

446
00:17:23,755 --> 00:17:24,856
DECREASED THEIR LIKELIHOOD OF

447
00:17:24,856 --> 00:17:29,761
BEING ABLE TO GET EXPOSED TO

448
00:17:29,761 --> 00:17:32,664
DRUGS.

449
00:17:32,664 --> 00:17:33,965
SUBSEQUENT STUDIES HAVE ACTUALLY

450
00:17:33,965 --> 00:17:35,233
EVALUATED THAT, YES, THAT PLAYED

451
00:17:35,233 --> 00:17:36,368
AN IMPORTANT ROLE, AND ALSO THAT

452
00:17:36,368 --> 00:17:38,069
THEY WERE AT HOME AND MANY TIMES

453
00:17:38,069 --> 00:17:39,170
THE PARENTS WERE THERE SO THEY

454
00:17:39,170 --> 00:17:42,674
WERE OVERSEEING THEM.

455
00:17:42,674 --> 00:17:44,175
SO WE WERE CONCERNED THAT ONCE

456
00:17:44,175 --> 00:17:45,944
THE SCHOOLS OPENED UP AND

457
00:17:45,944 --> 00:17:47,245
TEENAGERS WERE ABLE TO GET BACK

458
00:17:47,245 --> 00:17:49,281
TOGETHER AS THEY USED TO, WE

459
00:17:49,281 --> 00:17:50,915
WOULD SEE A RISE IN THE PATTERNS

460
00:17:50,915 --> 00:17:54,953
OF DRUG USE TO THOSE SIMILAR

461
00:17:54,953 --> 00:17:56,888
THAT WE HAD SEEN IN 2019.

462
00:17:56,888 --> 00:17:58,523
AND WHAT WE'VE SEEN IS THAT

463
00:17:58,523 --> 00:18:02,360
THAT'S NOT THE CASE.

464
00:18:02,360 --> 00:18:04,696
NEITHER FOR 2022 NOR 2023, WE

465
00:18:04,696 --> 00:18:08,700
HAVE SEEN THE PREVALENCE OF DRUG

466
00:18:08,700 --> 00:18:11,236
USE REBOUND TO WHAT IT WAS.

467
00:18:11,236 --> 00:18:12,637
IN FACT WE CONTINUE TO SEE IT

468
00:18:12,637 --> 00:18:14,739
DECREASE, AND THAT PERTAINS BOTH

469
00:18:14,739 --> 00:18:15,807
TO ILLICIT DRUGS, WHICH ARE THE

470
00:18:15,807 --> 00:18:20,745
ONES TO THE LEFT, AS WELL AS TO

471
00:18:20,745 --> 00:18:23,348
THALCOHOL AND TOBACCO.

472
00:18:23,348 --> 00:18:25,317
THIS IS ACTUALLY EXTREMELY

473
00:18:25,317 --> 00:18:28,053
NOTABLE IF YOU THINK ABOUT IT.

474
00:18:28,053 --> 00:18:30,355
PARTICULARLY, TOO, IS THE MAIN

475
00:18:30,355 --> 00:18:32,991
CHANGES ARE IN THE 12TH GRADERS

476
00:18:32,991 --> 00:18:35,327
AND THE 12TH GRADERS SORT OF ARE

477
00:18:35,327 --> 00:18:37,162
THE ONES THAT HAD THE HIGHEST

478
00:18:37,162 --> 00:18:39,230
PREVALENCE RATES OVERALL.

479
00:18:39,230 --> 00:18:41,299
THERE'S A FEW AREAS THAT THERE

480
00:18:41,299 --> 00:18:44,269
HAS BEEN WHAT APPEARS TO BE SOME

481
00:18:44,269 --> 00:18:47,305
INCREASES FOR TENTH GRADERS ON

482
00:18:47,305 --> 00:18:49,741
ILLICIT SUBSTANCES, BUT THE

483
00:18:49,741 --> 00:18:51,242
NUMBERS ARE SO, SO VERY LOW OF

484
00:18:51,242 --> 00:18:54,746
THOSE TEENAGERS THAT ARE TAKING

485
00:18:54,746 --> 00:18:58,683
THE COCAINE THAT BASICALLY IT'S

486
00:18:58,683 --> 00:19:00,885
VERY LIKELY TO BE JUST PART OF

487
00:19:00,885 --> 00:19:02,087
THIS ERROR SIGNALS AND

488
00:19:02,087 --> 00:19:06,024
VARIABILITY.

489
00:19:06,024 --> 00:19:07,892
IN THE LEGAL ONES, THE ONE THAT

490
00:19:07,892 --> 00:19:10,061
WE'RE SEEING IS THE INCREASES IN

491
00:19:10,061 --> 00:19:11,596
ALCOHOL BEVERAGES WITH CAFFEINE.

492
00:19:11,596 --> 00:19:13,131
AND WE WILL KEEP AN EYE ON THOSE

493
00:19:13,131 --> 00:19:17,369
TO SEE IF THEY ARE REALLY --

494
00:19:17,369 --> 00:19:20,438
THEY ARE -- THEY WILL CONTINUE

495
00:19:20,438 --> 00:19:22,107
LIKE THAT OR WHETHER THEY ARE AS

496
00:19:22,107 --> 00:19:25,043
I WAS IMPLYING THEY COULD BE

497
00:19:25,043 --> 00:19:28,546
JUST VARIABILITY.

498
00:19:28,546 --> 00:19:31,282
THIS SLIDE I'M SHOWING TO YOU TO

499
00:19:31,282 --> 00:19:34,119
ACTUALLY GET YOU A SENSE OF WHAT

500
00:19:34,119 --> 00:19:36,654
ARE THE -- AND TO THE LEFT, WHAT

501
00:19:36,654 --> 00:19:39,257
IS THE PREVALENCE OF PAST YEAR

502
00:19:39,257 --> 00:19:41,793
DRUG USE AMONG 12TH GRADERS, BUT

503
00:19:41,793 --> 00:19:43,495
I WANT YOU TO LOOK AT THE

504
00:19:43,495 --> 00:19:45,930
RANKING OF THE DRUGS THE

505
00:19:45,930 --> 00:19:47,031
TEENAGERS FAVOR BECAUSE ACTUALLY

506
00:19:47,031 --> 00:19:49,100
THAT GIVES US A PERSPECTIVE IN

507
00:19:49,100 --> 00:19:52,070
TERMS OF WHAT TO LOOK FOR AND

508
00:19:52,070 --> 00:19:54,572
HOW TO INTERPRET FINDINGS AND OF

509
00:19:54,572 --> 00:19:58,643
COURSE TARGET PREVENTION.

510
00:19:58,643 --> 00:19:59,944
ALCOHOL IS THE NUMBER ONE, THE

511
00:19:59,944 --> 00:20:01,246
MOST PREVALENT, WE'VE KNOWN THAT

512
00:20:01,246 --> 00:20:03,114
ALL ALONG, AND IN FACT IT

513
00:20:03,114 --> 00:20:04,983
REFLECTS THE FACT THAT IT IS A

514
00:20:04,983 --> 00:20:06,384
LEGAL SUBSTANCE AND THAT IT'S

515
00:20:06,384 --> 00:20:09,120
WIDESPREAD, AND SO THE

516
00:20:09,120 --> 00:20:12,857
ACCESSIBILITY, THE CULTURE AND

517
00:20:12,857 --> 00:20:13,958
THE NORMS MAKE IT MUCH MORE

518
00:20:13,958 --> 00:20:15,026
LIKELY THAT THEY WILL GET

519
00:20:15,026 --> 00:20:17,328
EXPOSED TO IT, EVEN WHEN IT IS

520
00:20:17,328 --> 00:20:18,663
ILLEGAL FOR TEENAGERS TO CONSUME

521
00:20:18,663 --> 00:20:19,197
IT.

522
00:20:19,197 --> 00:20:20,398
BUT IT HAS BEEN GOING DOWN

523
00:20:20,398 --> 00:20:25,203
SIGNIFICANTLY.

524
00:20:25,203 --> 00:20:27,172
I DO WANT YOU TO KNOW THAT

525
00:20:27,172 --> 00:20:28,940
SECOND ONE, I PUT A LITTLE RED

526
00:20:28,940 --> 00:20:30,442
STAR TO CATCH YOUR EYES WHICH IS

527
00:20:30,442 --> 00:20:32,410
ANY VAPING, BECAUSE ACTUALLY ANY

528
00:20:32,410 --> 00:20:36,915
VAPING NOW HOLDS THE SECOND

529
00:20:36,915 --> 00:20:39,717
FREQUENCY IN TERMS OF FREQUENCY

530
00:20:39,717 --> 00:20:43,788
POSITION WITH MAR MARIJUANA, AND

531
00:20:43,788 --> 00:20:44,556
TYPICALLY ALL THROUGH THE

532
00:20:44,556 --> 00:20:47,625
MONITORING THE FUTURE SURVEY,

533
00:20:47,625 --> 00:20:48,726
MARIJUANA HAS THE SECOND RANKING

534
00:20:48,726 --> 00:20:51,563
IN TERMS OF FREQUENCY AND NOT

535
00:20:51,563 --> 00:20:51,896
ANYMORE.

536
00:20:51,896 --> 00:20:55,066
WE'RE SEEING THAT VAPING -- AND

537
00:20:55,066 --> 00:21:00,104
AGAIN, IT REFLECTS THE VERY FAST

538
00:21:00,104 --> 00:21:02,740
UP TAKE OF VAPING BY TEENAGERS

539
00:21:02,740 --> 00:21:04,809
STARTING IN 2017, 2018 AND 2019,

540
00:21:04,809 --> 00:21:07,745
WHEN WE HAVE IN 2019 THE HIGHEST

541
00:21:07,745 --> 00:21:10,281
RATES OF PREVALENCE.

542
00:21:10,281 --> 00:21:13,017
VAPEING HAS GONE DOWN SINCE

543
00:21:13,017 --> 00:21:14,853
THEN, SINCE 2020, BUT IT HAS

544
00:21:14,853 --> 00:21:18,256
REMAINED VERY, VERY HIGH,

545
00:21:18,256 --> 00:21:20,458
BASICALLY 29%.

546
00:21:20,458 --> 00:21:25,864
IF YOU GO LOWER, VAPING NICOTINE

547
00:21:25,864 --> 00:21:27,499
IS THE MAIN DRIVER OF VAPING,

548
00:21:27,499 --> 00:21:30,268
BUT SO IS ACTUALLY VAPING OF

549
00:21:30,268 --> 00:21:33,538
CANNABIS ALSO IS QUITE FREQUENT

550
00:21:33,538 --> 00:21:36,040
AMONG TEENAGERS.

551
00:21:36,040 --> 00:21:41,279
I AM ALSO DISPLAYING THAT

552
00:21:41,279 --> 00:21:44,015
ACTUALLY TO YOUR RIGHT, LSD AND

553
00:21:44,015 --> 00:21:46,551
TO YOUR LEFT ACTUALLY MORE

554
00:21:46,551 --> 00:21:57,829
NOTABLE, HA LEW LE HA LE HALLUC.

555
00:22:01,933 --> 00:22:03,101
 -- IN THE PAST YEAR, AND AGAIN,

556
00:22:03,101 --> 00:22:04,469
THIS IS THE HIGHEST THAT WE'VE

557
00:22:04,469 --> 00:22:09,440
SEEN IT.

558
00:22:09,440 --> 00:22:14,045
THEN TO THE RIGHT YOU SEE

559
00:22:14,045 --> 00:22:16,147
PSYCHOTHERAPEUTICS, THE REDS.

560
00:22:16,147 --> 00:22:18,983
I HIGHLIGHT THEM BECAUSE THEY

561
00:22:18,983 --> 00:22:22,153
ARE -- COUGH MEDICINE,

562
00:22:22,153 --> 00:22:24,889
AMPHETAMINES, TRANQUILIZERS,

563
00:22:24,889 --> 00:22:27,058
PRESCRIPTION OPIOIDS SUCH AS

564
00:22:27,058 --> 00:22:28,826
VICODIN AND OXYCONTIN.

565
00:22:28,826 --> 00:22:30,995
THEY CONTINUE TO PERSIST, VAIR

566
00:22:30,995 --> 00:22:36,034
VALUETHEIRVALUES ARE MUCH LOWERT

567
00:22:36,034 --> 00:22:37,535
WE HAVE SEEN IN THE PAST, BUT

568
00:22:37,535 --> 00:22:39,504
THEY ARE AMONG THE DRUGS THAT

569
00:22:39,504 --> 00:22:40,505
TEENAGERS WILL EXPERIMENT WITH,

570
00:22:40,505 --> 00:22:43,241
AND I'LL BRING IT BACK LATER

571
00:22:43,241 --> 00:22:47,378
BECAUSE THIS HAS LED TO SOME

572
00:22:47,378 --> 00:22:48,913
SOME VERY NEGATIVE OUTCOMES.

573
00:22:48,913 --> 00:22:50,982
I DO WANT YOU -- LET'S MOVE TO

574
00:22:50,982 --> 00:22:52,183
THE RIGHT TO SEE THE SLIDES

575
00:22:52,183 --> 00:22:53,785
THERE, AND BASICALLY IT SHOWS

576
00:22:53,785 --> 00:22:57,121
JUST TO GET YOU AN IDEA OF THE

577
00:22:57,121 --> 00:22:58,890
TRENDS THAT I WAS REPORTING ON

578
00:22:58,890 --> 00:23:00,191
WITH RESPECT TO THE DECREASES IN

579
00:23:00,191 --> 00:23:03,027
DRUG USE, IN GENERAL, THESE HAVE

580
00:23:03,027 --> 00:23:04,896
NOT -- THESE HAVE BEEN MUCH MORE

581
00:23:04,896 --> 00:23:06,598
STABLE FOR MARIJUANA, WHERE WE

582
00:23:06,598 --> 00:23:08,933
HAVE NOT SEEN ANY MAJOR

583
00:23:08,933 --> 00:23:10,802
DECREASES, VERY STABLE, PERHAPS

584
00:23:10,802 --> 00:23:12,337
SLIGHTLY WITH 2020 AND THEN THAT

585
00:23:12,337 --> 00:23:17,008
HAS STAYED THE SAME BUT ON THE

586
00:23:17,008 --> 00:23:19,210
OTHER HAND, BUT WHAT HAVE BEEN

587
00:23:19,210 --> 00:23:20,979
KEEPING AN EYE ON IS, AGAIN, NOT

588
00:23:20,979 --> 00:23:22,480
BECOMING COMPLACENT AND SAYING,

589
00:23:22,480 --> 00:23:23,381
WELL, ADOLESCENT DRUG USE IS

590
00:23:23,381 --> 00:23:25,249
GOING DOWN, THAT'S CORRECT.

591
00:23:25,249 --> 00:23:27,085
MARIJUANA IS QUITE STABLE.

592
00:23:27,085 --> 00:23:28,853
AND VAPING IS GOING DOWN, BUT

593
00:23:28,853 --> 00:23:31,789
IT'S A VERY HIGH LEVEL.

594
00:23:31,789 --> 00:23:33,891
BUT LOOK AT THE LOWER ONE TO THE

595
00:23:33,891 --> 00:23:35,393
RIGHT, WHICH ACTUALLY SHOWS THAT

596
00:23:35,393 --> 00:23:37,395
THAT'S THE DAILY CONSUMPTION,

597
00:23:37,395 --> 00:23:40,865
ALMOST DAILY CONSUMPTION OF

598
00:23:40,865 --> 00:23:42,834
MARIJUANA, AND THIS IS

599
00:23:42,834 --> 00:23:44,268
CONCERNING CERTAINLY IN MY BRAIN

600
00:23:44,268 --> 00:23:46,904
BECAUSE OF HOW STABLE IT IS, AND

601
00:23:46,904 --> 00:23:53,244
IT'S BEEN APPROXIMATELY A 6%,

602
00:23:53,244 --> 00:23:54,879
CONSIDERING THAT THE CONTENT OF

603
00:23:54,879 --> 00:23:57,615
THC IN MARIJUANA HAS BEEN

604
00:23:57,615 --> 00:24:00,885
INCREASING SIGNIFICANTLY AND

605
00:24:00,885 --> 00:24:02,420
THAT IT IS THE REGULAR USE OF

606
00:24:02,420 --> 00:24:04,188
MARIJUANA WITH A HIGH CONTENT

607
00:24:04,188 --> 00:24:05,156
ASSOCIATED WITH THE MORE

608
00:24:05,156 --> 00:24:06,024
NEGATIVE OUTCOMES, THIS IS

609
00:24:06,024 --> 00:24:08,660
SOMETHING THAT IS WORRISOME, AND

610
00:24:08,660 --> 00:24:13,364
THAT OBVIOUSLY THAT WE

611
00:24:13,364 --> 00:24:14,699
CAN MONITOR AND FOLLOW CLOSELY

612
00:24:14,699 --> 00:24:16,100
TO SEE WHAT ARE THE CONSEQUENCES

613
00:24:16,100 --> 00:24:18,069
OF REGULAR USE OF MARIJUANA IN

614
00:24:18,069 --> 00:24:23,408
TEENAGERS.

615
00:24:23,408 --> 00:24:25,076
AND HOW DO THESE FINDINGS I'M

616
00:24:25,076 --> 00:24:27,011
SHOWING YOU HERE IN TERMS OF

617
00:24:27,011 --> 00:24:28,579
RANKING OF PREFERENCES OF

618
00:24:28,579 --> 00:24:31,416
TEENAGERS FOR DRUGS -- IN TERMS

619
00:24:31,416 --> 00:24:33,151
OF HOW DO THEY COMPARE WITH THE

620
00:24:33,151 --> 00:24:36,888
ADULTS IN TERMS OF VAPING, ALONG

621
00:24:36,888 --> 00:24:39,390
WITH MARIJUANA, SIDELY SIDE.

622
00:24:39,390 --> 00:24:40,291
IMPORTANTLY THAT COMMENT THAT

623
00:24:40,291 --> 00:24:42,026
WE'VE SEEN THE HIGHER RATES FOR

624
00:24:42,026 --> 00:24:44,529
THE USE OF HALLUCINOGENS.

625
00:24:44,529 --> 00:24:46,197
SO LET'S JUMP, THEN, INTO THE

626
00:24:46,197 --> 00:24:47,598
SURVEY FROM THE NATIONAL SURVEY

627
00:24:47,598 --> 00:24:49,767
OF DRUG USE AND HEALTH FROM

628
00:24:49,767 --> 00:24:51,335
SAMHSA, WHICH WAS JUST RELEASED

629
00:24:51,335 --> 00:24:53,604
LAST YEAR FOR 2022.

630
00:24:53,604 --> 00:24:55,807
AND JUST FOR ADOLESCENTS, THE

631
00:24:55,807 --> 00:24:58,109
NUMBER ONE DRUG IN TERMS OF

632
00:24:58,109 --> 00:25:01,946
PREVALENCE IS ALCOHOL.

633
00:25:01,946 --> 00:25:03,414
THE SECOND ONE ARE TOBACCO

634
00:25:03,414 --> 00:25:03,881
PRODUCTS.

635
00:25:03,881 --> 00:25:05,750
VERY MUCH SIDE BY SIDE WITH

636
00:25:05,750 --> 00:25:06,617
MARIJUANA.

637
00:25:06,617 --> 00:25:10,855
BUT YOU ALSO SEE THAT AMONG THE

638
00:25:10,855 --> 00:25:12,523
FOUR TOP RANKING DRUGS IN TERMS

639
00:25:12,523 --> 00:25:15,159
OF PREVALENCE IS NICOTINE

640
00:25:15,159 --> 00:25:15,693
VAPING.

641
00:25:15,693 --> 00:25:21,265
SO EVEN THOUGH THE NICOTINE

642
00:25:21,265 --> 00:25:23,367
VAPING IS THE HIGHEST AMONG

643
00:25:23,367 --> 00:25:25,103
TEENAGERS, WE'RE SEEING ALSO

644
00:25:25,103 --> 00:25:26,204
VERY HIGH RATES AMONG

645
00:25:26,204 --> 00:25:28,372
INDIVIDUALS THAT ARE 12 YEARS OR

646
00:25:28,372 --> 00:25:35,847
OLDER, WHICH IS WHAT TH THE NSDH

647
00:25:35,847 --> 00:25:38,249
SURVEY IS SHOWING YOU HERE.

648
00:25:38,249 --> 00:25:41,352
THE RED STAR INDICATES

649
00:25:41,352 --> 00:25:41,686
HALLUCINOGENS.

650
00:25:41,686 --> 00:25:44,489
SO NOW HALLUCINOGENS ARE AMONG

651
00:25:44,489 --> 00:25:45,890
THE SIX MOST FREQUENTLY USED

652
00:25:45,890 --> 00:25:48,760
SUBSTANCES IN OUR COUNTRY.

653
00:25:48,760 --> 00:25:50,161
NOW, THIS IS WHERE WE ARE RIGHT

654
00:25:50,161 --> 00:25:52,997
NOW, BUT IT'S ALSO WORTHWHILE TO

655
00:25:52,997 --> 00:25:55,733
LOOK AT ANOTHER INDICATOR FROM

656
00:25:55,733 --> 00:25:59,137
THE NSDUH, BECAUSE IT ACTUALLY

657
00:25:59,137 --> 00:26:00,972
ALLOWS US TO PREDICT WHERE WE'RE

658
00:26:00,972 --> 00:26:02,073
GOING TO BE IN THE FUTURE, WHAT

659
00:26:02,073 --> 00:26:02,940
ARE SOME OF THE CHALLENGES WE'RE

660
00:26:02,940 --> 00:26:03,841
GOING TO BE SEEING.

661
00:26:03,841 --> 00:26:08,746
SO THEY DO REPORT ON PAST YEAR

662
00:26:08,746 --> 00:26:10,281
INITIATES OF SUBSTANCES ON

663
00:26:10,281 --> 00:26:11,816
PEOPLE 12 YEARS OR OLDER, AND I

664
00:26:11,816 --> 00:26:13,217
FIND THESE EXTREMELY HELPFUL.

665
00:26:13,217 --> 00:26:14,318
BECAUSE IF YOU LOOK AT IT FROM

666
00:26:14,318 --> 00:26:15,753
THAT PERSPECTIVE, YOU CAN SEE

667
00:26:15,753 --> 00:26:19,123
THAT NICOTINE VAPING IS THE

668
00:26:19,123 --> 00:26:19,423
NUMBER ONE.

669
00:26:19,423 --> 00:26:22,326
SO EVEN THOUGH NICOTINE VAPING

670
00:26:22,326 --> 00:26:31,936
WAS THE 4,014TH RANKI -- THE 14N

671
00:26:31,936 --> 00:26:35,006
PREVALENCE, THE SECOND ONE IS

672
00:26:35,006 --> 00:26:35,673
FOR ALCOHOL.

673
00:26:35,673 --> 00:26:38,743
AND I FOUND IT QUITE NOTABLE

674
00:26:38,743 --> 00:26:40,144
THAT -- I DON'T THINK I'VE EVER

675
00:26:40,144 --> 00:26:48,619
SEEN ANYTHING LIKE THIS -- BASED

676
00:26:48,619 --> 00:26:50,254
ON THESE NUMBERS AND IT'S CLOSE

677
00:26:50,254 --> 00:26:53,324
TO 50% HIGHER, WHICH MEANS THAT

678
00:26:53,324 --> 00:26:54,992
IT IS -- WE CAN PREDICT AND WE

679
00:26:54,992 --> 00:26:57,995
CAN EXPECT THAT THERE WILL BE

680
00:26:57,995 --> 00:26:59,430
MORE INDIVIDUALS IN THE FUTURE

681
00:26:59,430 --> 00:27:06,270
THAT WILL BE ADDICTION TO

682
00:27:06,270 --> 00:27:07,705
NICOTINE TRIGGERED BY ANYTHING

683
00:27:07,705 --> 00:27:09,006
TEEN VAPING.

684
00:27:09,006 --> 00:27:10,541
AND A LOT OF PEOPLE HAVE BEEN

685
00:27:10,541 --> 00:27:11,642
CONCERNED THAT THIS COULD

686
00:27:11,642 --> 00:27:12,844
TRANSLATE INTO HIGHER USE OF

687
00:27:12,844 --> 00:27:15,813
TOBACCO PRODUCTS

688
00:27:15,813 --> 00:27:18,049
FOR WHICH THERE'S SOME EVIDENCE

689
00:27:18,049 --> 00:27:19,517
THAT THAT ACTUALLY DOES HAPPEN.

690
00:27:19,517 --> 00:27:21,152
BUT IN AND OF ITSELF, IT IS ALSO

691
00:27:21,152 --> 00:27:22,353
LIKELY THAT NICOTINE MAY BECOME

692
00:27:22,353 --> 00:27:25,122
A MUCH MORE PREVALENT BY ITSELF

693
00:27:25,122 --> 00:27:26,958
SUBSTANCE THAT WE HAVE SEEN NOW

694
00:27:26,958 --> 00:27:30,361
FOR MANY YEARS.

695
00:27:30,361 --> 00:27:34,398
YOU ALSO SEE THAT THE THIRD ONE

696
00:27:34,398 --> 00:27:36,133
IN INITIATES CONTINUES TO BE

697
00:27:36,133 --> 00:27:36,467
MARIJUANA.

698
00:27:36,467 --> 00:27:38,436
THAT IS A SERIOUS PROBLEM

699
00:27:38,436 --> 00:27:41,505
BECAUSE WE'VE SEEN ALL ALONG

700
00:27:41,505 --> 00:27:43,441
THAT WITH LEGALIZATION OF

701
00:27:43,441 --> 00:27:44,275
MARIJUANA ACROSS THE STATES,

702
00:27:44,275 --> 00:27:45,776
WE'RE SEEING A SIGNIFICANT RISE

703
00:27:45,776 --> 00:27:47,979
IN THE USE OF MARIJUANA ACROSS

704
00:27:47,979 --> 00:27:50,214
ALL AGES OTHER THAN TEENAGERS,

705
00:27:50,214 --> 00:27:58,022
AS I WAS PRESENTING BEFORE.

706
00:27:58,022 --> 00:27:59,390
I ALSO PUT THIS LITTLE STAR HERE

707
00:27:59,390 --> 00:28:01,292
TO SHOW YOU THAT THE NUMBER

708
00:28:01,292 --> 00:28:05,129
6 ACTUALLY IN NEW INITIATES IS

709
00:28:05,129 --> 00:28:05,563
HALLUCINOGENS.

710
00:28:05,563 --> 00:28:09,066
WHICH MEANS WE ARE TO EXPECT, IF

711
00:28:09,066 --> 00:28:12,036
THINGS AND TRENDS CONTINUE

712
00:28:12,036 --> 00:28:13,237
LIKELY, HALLUCINOGENICS WILL

713
00:28:13,237 --> 00:28:15,072
BECOME MUCH MORE FREQUENTLY USED

714
00:28:15,072 --> 00:28:17,174
THAN WHAT WE HAVE BEEN SEEING

715
00:28:17,174 --> 00:28:19,477
UNTIL NOW, AND WHAT YOU'RE ALSO

716
00:28:19,477 --> 00:28:23,314
STARTING TO SEE IN ADOLESCENTS,

717
00:28:23,314 --> 00:28:31,489
AS I SHOWED.

718
00:28:31,489 --> 00:28:33,124
NOW, ONE OF THE ASPECTS THAT I

719
00:28:33,124 --> 00:28:34,325
LIKE TO TIE IT WHEN I SPEAK

720
00:28:34,325 --> 00:28:37,094
ABOUT THE PREVALENCE OF DRUG USE

721
00:28:37,094 --> 00:28:38,396
AND HOW CONCERNING IT IS THAT

722
00:28:38,396 --> 00:28:41,098
WE'RE SEEING SOME OF THESE

723
00:28:41,098 --> 00:28:41,999
TRENDS, PARTICULARLY WITH

724
00:28:41,999 --> 00:28:44,835
REGULAR USE OF MARIJUANA, AND

725
00:28:44,835 --> 00:28:46,270
CERTAINLY NOW WITH NICOTINE

726
00:28:46,270 --> 00:28:48,673
VAPING AND NICOTINE AND VAPING

727
00:28:48,673 --> 00:28:51,509
OF THCs, WHAT ARE THE

728
00:28:51,509 --> 00:28:53,811
CONSEQUENCES.

729
00:28:53,811 --> 00:28:55,179
THAT IS ACTUALLY WHAT ULTIMATELY

730
00:28:55,179 --> 00:28:56,280
LED US TO START IN PARTNERSHIP

731
00:28:56,280 --> 00:28:58,015
WITH THE ALCOHOL INSTITUTES AND

732
00:28:58,015 --> 00:28:59,583
OTHER INSTITUTES, THE ABCD

733
00:28:59,583 --> 00:29:03,988
STUDY, TO TRY TO UNDERSTAND IN A

734
00:29:03,988 --> 00:29:05,056
PROSPECTIVE DESIGN DOING A STUDY

735
00:29:05,056 --> 00:29:06,824
TO ADDRESS THE QUESTIONS OF WHAT

736
00:29:06,824 --> 00:29:09,660
ARE THE CONSEQUENCES OF EXPOSURE

737
00:29:09,660 --> 00:29:11,295
TO CANNABIS TO THE HUMAN BRAIN,

738
00:29:11,295 --> 00:29:14,265
BRAIN DEVELOPMENT, EMERGENCE OF

739
00:29:14,265 --> 00:29:15,900
PSYCHIATRIC SYMPTOMS AND

740
00:29:15,900 --> 00:29:22,773
DISORDERS, AND ULTIMATELY,

741
00:29:22,773 --> 00:29:23,975
ABILITY TO ACTUALLY SUCCEED AND

742
00:29:23,975 --> 00:29:24,976
PERFORM AS AN ADULT.

743
00:29:24,976 --> 00:29:27,044
THAT'S HOW THE ABCD WAS BORN,

744
00:29:27,044 --> 00:29:30,881
AND WE LAUNCHED IT IN TWEB 17.

745
00:29:30,881 --> 00:29:31,849
 -- IN 2017.

746
00:29:31,849 --> 00:29:34,485
IT HAS CONTINUED SINCE THEN,

747
00:29:34,485 --> 00:29:36,354
CHILDREN THAT WERE THEN 9 TO 10

748
00:29:36,354 --> 00:29:38,089
YEARS OLD WHEN THEY WERE

749
00:29:38,089 --> 00:29:40,391
RECRUITED, OF WHICH 96.3% HAVE

750
00:29:40,391 --> 00:29:42,560
BEEN RETAINED SINCE THEN.

751
00:29:42,560 --> 00:29:46,597
PERIODICALLY IMPANELIN IMAGING Y

752
00:29:46,597 --> 00:29:48,699
TWO YEARS, EVALUATING THEM

753
00:29:48,699 --> 00:29:51,769
COGNITIVELY, BEHAVIORALLY, WITH

754
00:29:51,769 --> 00:29:58,242
SURVEYS FOR SOCIAL PATTERNS, TO

755
00:29:58,242 --> 00:30:01,278
ADDRESS PHYSICAL ACTIVITIES WITH

756
00:30:01,278 --> 00:30:03,247
IN DEPTH CHARACTERIZATION OF

757
00:30:03,247 --> 00:30:05,883
THEIR SOCIOECONOMICAL

758
00:30:05,883 --> 00:30:08,285
ENVIRONMENTS, AND DEPOSITING

759
00:30:08,285 --> 00:30:10,588
THAT DATA ON A YEARLY BASIS IN

760
00:30:10,588 --> 00:30:14,291
AN OPEN ACCESS FORMAT TO ALLOW

761
00:30:14,291 --> 00:30:16,494
RESEARCHERS FROM ALL DISCIPLINES

762
00:30:16,494 --> 00:30:19,764
TO BE ABLE TO TAKE ADVANTAGE OF

763
00:30:19,764 --> 00:30:23,367
THETHIS EXTRAORDINARY RICH DATAT

764
00:30:23,367 --> 00:30:24,668
AND ANALYZE IT IN THE WAYS THAT

765
00:30:24,668 --> 00:30:26,337
IN THE PAST, NO DATASET HAVE

766
00:30:26,337 --> 00:30:28,072
BEEN MADE AVAILABLE FOR

767
00:30:28,072 --> 00:30:28,672
UNDERSTANDING THE HUMAN BRAIN

768
00:30:28,672 --> 00:30:33,644
DEVELOPMENT.

769
00:30:33,644 --> 00:30:35,413
THIS PROGRAM HAS BEEN INCREDIBLY

770
00:30:35,413 --> 00:30:39,116
ABLY LED BY DR. DOWLING AND HER

771
00:30:39,116 --> 00:30:40,451
TEAM, AND AGAIN, I WANT TO

772
00:30:40,451 --> 00:30:42,219
REITERATE THAT THIS HAS BEEN

773
00:30:42,219 --> 00:30:44,822
DONE IN CLOSE COLLABORATION WITH

774
00:30:44,822 --> 00:30:48,626
THE ALCOHOL INSTITUTE, AS WELL

775
00:30:48,626 --> 00:30:51,295
AS OTHER INSTITUTES LIKE THE

776
00:30:51,295 --> 00:30:51,829
NIMH.

777
00:30:51,829 --> 00:30:53,464
THIS ACTUALLY -- THE WAY THAT

778
00:30:53,464 --> 00:30:56,300
WE'VE ALSO BEEN MAXIMIZING THE

779
00:30:56,300 --> 00:30:58,102
UTILIZATION OF THESE DATABASES

780
00:30:58,102 --> 00:31:03,874
IS JUST BY PUTTING THEM AS OPEN

781
00:31:03,874 --> 00:31:04,842
ACCESS, BUT ALL OF THE

782
00:31:04,842 --> 00:31:06,377
INSTITUTES YOU SEE HERE HAVE

783
00:31:06,377 --> 00:31:07,578
ALSO REQUESTED PROPOSALS IN

784
00:31:07,578 --> 00:31:09,880
ORDER TO BE ABLE -- ENCOURAGING

785
00:31:09,880 --> 00:31:11,148
RESEARCHERS TO TAKE ADVANTAGE OF

786
00:31:11,148 --> 00:31:14,685
THE DATABASE TO ASK FOR GRANTS

787
00:31:14,685 --> 00:31:16,620
THAT ACTUALLY ENABLE THEM TO ASK

788
00:31:16,620 --> 00:31:17,088
SPECIFIC QUESTIONS.

789
00:31:17,088 --> 00:31:19,056
AND THIS FIGURE HERE SHOWS THE

790
00:31:19,056 --> 00:31:21,592
RELATIVE NUMBER OF GRANTS THAT

791
00:31:21,592 --> 00:31:24,962
HAVE BEEN AWARDED BY THE

792
00:31:24,962 --> 00:31:26,797
DIFFERENT INSTITUTES IN ORDER TO

793
00:31:26,797 --> 00:31:31,335
EXPLOIT THE RICHNESS OF THE AB 

794
00:31:31,335 --> 00:31:34,905
ABCD.

795
00:31:34,905 --> 00:31:37,007
THE CONSEQUENCES ARE HERE, THE

796
00:31:37,007 --> 00:31:37,775
PUBLICATIONS.

797
00:31:37,775 --> 00:31:39,510
AS OF NOW, MY UNDERSTANDING IS

798
00:31:39,510 --> 00:31:42,146
THERE ARE 832 PUBLICATIONS, IT'S

799
00:31:42,146 --> 00:31:42,913
PROBABLY MORE THAN THAT BUT

800
00:31:42,913 --> 00:31:43,881
THAT'S THE LATEST NUMBERS I

801
00:31:43,881 --> 00:31:45,082
HAVE.

802
00:31:45,082 --> 00:31:51,088
AND MOST OF THEM ARE BASICALLY

803
00:31:51,088 --> 00:31:51,755
EMPIRICAL DATABASED ON NEW

804
00:31:51,755 --> 00:31:52,089
RESULTS.

805
00:31:52,089 --> 00:31:55,359
OTHERS ARE BASED ON COMMENTARIES

806
00:31:55,359 --> 00:31:56,994
AND ANALYSIS OF THE SIGNIFICANCE

807
00:31:56,994 --> 00:31:58,329
OF THESE FINDINGS.

808
00:31:58,329 --> 00:31:59,663
IT HAS BEEN QUITE EXTRAORDINARY,

809
00:31:59,663 --> 00:32:04,101
AND I WOULD SAY AS SOMEONE THAT

810
00:32:04,101 --> 00:32:07,171
HAS BEEN OVERSEEING HOW THE ABCD

811
00:32:07,171 --> 00:32:08,506
HAS BEEN GROWING AND AS SOMEONE

812
00:32:08,506 --> 00:32:11,675
THAT HAS BEEN INVOLVED IN

813
00:32:11,675 --> 00:32:13,077
NEUROIMAGING, TO ME, IT HAS BEEN

814
00:32:13,077 --> 00:32:15,179
A SPECTACULAR SUCCESS.

815
00:32:15,179 --> 00:32:17,681
NOT JUST AS WE WERE INITIALLY

816
00:32:17,681 --> 00:32:20,951
INTENDING, I DON'T THINK -- I

817
00:32:20,951 --> 00:32:24,588
MEAN, I WAS OBVIOUSLY VERY, VERY

818
00:32:24,588 --> 00:32:25,656
EXCITED ABOUT THIS PROGRAM BUT I

819
00:32:25,656 --> 00:32:26,757
NEVER PREDICTED IT WOULD HAVE

820
00:32:26,757 --> 00:32:29,059
SUCH A GIGANTIC IMPACT, NOT JUST

821
00:32:29,059 --> 00:32:30,628
IN TERMS OF UNDERSTANDING HOW

822
00:32:30,628 --> 00:32:33,197
THE HUMAN BRAIN WORKS, BUT

823
00:32:33,197 --> 00:32:34,632
IMPORTANTLY, ON GIVING US AN

824
00:32:34,632 --> 00:32:36,400
INSIGHT OF WHY SOCIAL

825
00:32:36,400 --> 00:32:40,871
DETERMINANTS OF HEALTH COULD

826
00:32:40,871 --> 00:32:42,506
INFLUENCE THOSE PATTERNS OF

827
00:32:42,506 --> 00:32:46,644
DEVELOPMENT AND ALSO HOW THAT

828
00:32:46,644 --> 00:32:49,180
LEADS TO MENTAL DISORDERS.

829
00:32:49,180 --> 00:32:51,048
IT'S ALSO BEEN INCREDIBLY

830
00:32:51,048 --> 00:32:52,349
CONSEQUENTIAL IN TERMS OF

831
00:32:52,349 --> 00:32:55,219
ADVANCING NEURO IMAGING ITSELF,

832
00:32:55,219 --> 00:32:57,488
AND PREPARING US FOR THE

833
00:32:57,488 --> 00:33:00,991
OPPORTUNITY OF CREATING

834
00:33:00,991 --> 00:33:03,194
DATABASES THAT OF COURSE CAN BE

835
00:33:03,194 --> 00:33:04,828
USED IN ORDER TO BUILD MODELS

836
00:33:04,828 --> 00:33:07,464
FOR ARTIFICIAL INTELLIGENCE AND

837
00:33:07,464 --> 00:33:09,533
MACHINE LEARNING AND PREDICTION.

838
00:33:09,533 --> 00:33:11,068
SO IT HAS BEEN JUST AN

839
00:33:11,068 --> 00:33:14,638
EXTRAORDINARY SUCCESS.

840
00:33:14,638 --> 00:33:15,639
A PART OF THE SUCCESS HAS BEEN

841
00:33:15,639 --> 00:33:17,274
THE OPEN ACCESS FORMAT THAT

842
00:33:17,274 --> 00:33:19,143
ALLOWS, AGAIN, FOR RESEARCHERS

843
00:33:19,143 --> 00:33:23,948
TO REALLY DWELL INTO THE COMP 

844
00:33:23,948 --> 00:33:24,582
COMPLEXITY.

845
00:33:24,582 --> 00:33:25,216
IT HAS BEEN SOMETIMES A LITTLE

846
00:33:25,216 --> 00:33:26,483
BIT OF A ROLLER COASTER.

847
00:33:26,483 --> 00:33:28,018
WE HAD WANTED TO BE ABLE TO

848
00:33:28,018 --> 00:33:29,887
RELEASE THE DATA ON A YEARLY

849
00:33:29,887 --> 00:33:33,691
BASIS, BUT WE HAD SUFFERED

850
00:33:33,691 --> 00:33:36,560
ACTUALLY SOME SETBACKS BECAUSE

851
00:33:36,560 --> 00:33:37,761
OF THE DIFFICULTIES OF RELEASING

852
00:33:37,761 --> 00:33:41,031
DATA THAT IS SO COMPLEX, AND SO

853
00:33:41,031 --> 00:33:42,533
FINALLY WE WERE DELAYED BY

854
00:33:42,533 --> 00:33:44,201
ALMOST I THINK ONE YEAR BUT WE

855
00:33:44,201 --> 00:33:50,674
WERE ABLE TO HAVE THE ABCD

856
00:33:50,674 --> 00:33:52,610
5.1 DATA RELEASED AND FINALLY

857
00:33:52,610 --> 00:33:54,578
WILL BE ON TRACK BEFORE TO HAVE

858
00:33:54,578 --> 00:33:55,679
THE ANNUAL RELEASES.

859
00:33:55,679 --> 00:33:58,649
AND THESE VERY SUCCESSFUL ABCD

860
00:33:58,649 --> 00:33:59,950
STUDY ACTUALLY SERVED FOR THE

861
00:33:59,950 --> 00:34:04,221
IPS PRAITION INSPIRATION OF THEN

862
00:34:04,221 --> 00:34:05,956
AND CHILD DEVELOPMENT STUDY,

863
00:34:05,956 --> 00:34:07,391
WHICH ALSO AIMS TO LOOK AT BRAIN

864
00:34:07,391 --> 00:34:08,325
DEVELOPMENT, EXCEPT IN THIS ONE,

865
00:34:08,325 --> 00:34:09,560
WE STARTED WHEN THEY WERE 9 TO

866
00:34:09,560 --> 00:34:12,963
10, AND IN THIS WURNTION WE'RE E

867
00:34:12,963 --> 00:34:14,565
STARTING WHEN THE WOMEN ARE

868
00:34:14,565 --> 00:34:17,301
PREGNANT OR JUST -- A NEWBORN IS

869
00:34:17,301 --> 00:34:18,869
NEW-BORN, IN ORDER TO ACTUALLY

870
00:34:18,869 --> 00:34:21,205
ASK THE SAME QUESTIONS, HOW DOES

871
00:34:21,205 --> 00:34:24,408
THE HUMAN BRAIN DEVELOP, AND TO

872
00:34:24,408 --> 00:34:26,810
FOLLOW THESE NEONATES UNTIL THEY

873
00:34:26,810 --> 00:34:30,848
REACH FOR AT LEAST 10 YEARS.

874
00:34:30,848 --> 00:34:33,717
WE FUNDED THE PROJECTS LAST

875
00:34:33,717 --> 00:34:39,690
YEAR, IN SEPTEMBER OF 2023, AND

876
00:34:39,690 --> 00:34:41,358
27 SITES WERE SELECTED, AND

877
00:34:41,358 --> 00:34:43,227
SINCE THEN, THEY HAVE BEEN ABLE

878
00:34:43,227 --> 00:34:48,399
TO RECRUIT 844 PAIRS, A MOTHER

879
00:34:48,399 --> 00:34:48,932
AND A CHILD.

880
00:34:48,932 --> 00:34:52,102
AND THAT IS 78.2% OF THE

881
00:34:52,102 --> 00:34:54,738
ENROLLMENT GOAL, WHICH IS

882
00:34:54,738 --> 00:34:55,406
ACTUALLY -- WHICH IS GOOD

883
00:34:55,406 --> 00:35:00,077
BECAUSE IT'S AN EXTRAORDINARILY

884
00:35:00,077 --> 00:35:00,644
CHALLENGING STUDY.

885
00:35:00,644 --> 00:35:02,046
IN A WAY, IT'S MORE CHALLENGING

886
00:35:02,046 --> 00:35:03,480
THAN THE ABCD, BECAUSE WHAT

887
00:35:03,480 --> 00:35:05,983
HAPPENS IS WE ARE AIMING TO

888
00:35:05,983 --> 00:35:13,857
RECRUIT AT LEAST 25% OF INFANTS

889
00:35:13,857 --> 00:35:15,392
WHOSE MOTHER HAD BEEN EXPOSED TO

890
00:35:15,392 --> 00:35:16,493
DRUGS DURING PREGNANCY.

891
00:35:16,493 --> 00:35:19,563
AND THIS IS CHALLENGING, BECAUSE

892
00:35:19,563 --> 00:35:22,399
MANY WOMEN ARE AFRAID TO

893
00:35:22,399 --> 00:35:23,701
ACTUALLY SEEK OUT HELP IF THEY

894
00:35:23,701 --> 00:35:26,103
ARE TAKING DRUGS, AND THEY ARE

895
00:35:26,103 --> 00:35:27,304
PREGNANT, FOR FEAR THAT THEIR

896
00:35:27,304 --> 00:35:30,174
CHILDREN WOULD BE REMOVED FROM

897
00:35:30,174 --> 00:35:33,444
THEM, OR IN SOME VERY PUNITIVE

898
00:35:33,444 --> 00:35:36,080
STATES, THEY MAY END UP IN JAIL.

899
00:35:36,080 --> 00:35:39,149
SO CONSIDERING THAT, AND WE WERE

900
00:35:39,149 --> 00:35:43,620
AWARE OF THAT, WE HAD ACTUALLY

901
00:35:43,620 --> 00:35:45,356
DONE -- BEFORE WE DID THE FORMAL

902
00:35:45,356 --> 00:35:47,324
RELEASE LAST YEAR, WE HAD A

903
00:35:47,324 --> 00:35:48,759
TWO-YEAR PILOT PROGRAMMING TO

904
00:35:48,759 --> 00:35:50,094
GET A SENSE OF WHAT WERE THE

905
00:35:50,094 --> 00:35:53,030
CHALLENGES AND ALSO ALLOW FOR

906
00:35:53,030 --> 00:35:58,535
THE DIFFERENT SITES TO DO PILOTS

907
00:35:58,535 --> 00:36:00,471
OF THE DIFFERENT VISITS

908
00:36:00,471 --> 00:36:01,538
DEPENDING ON THE AGE OF THESE

909
00:36:01,538 --> 00:36:05,743
INFANTS.

910
00:36:05,743 --> 00:36:07,077
THIS ACTUALLY SHOWS YOU THE

911
00:36:07,077 --> 00:36:07,945
DIFFERENT SITES.

912
00:36:07,945 --> 00:36:09,146
THERE IS VARIABILITY ON WHERE

913
00:36:09,146 --> 00:36:11,448
THEY ARE RIGHT NOW, AND THIS

914
00:36:11,448 --> 00:36:19,623
PLOT HERE SHOWS YOU OF THE

915
00:36:19,623 --> 00:36:22,493
884 -- 844 INFANTS THAT HAVE

916
00:36:22,493 --> 00:36:26,630
BEEN RECRUITED, 34% HAVE HAD A

917
00:36:26,630 --> 00:36:28,165
HISTORY OF PRENATAL SUBSTANCE

918
00:36:28,165 --> 00:36:29,700
USE, WHICH IS HIGHER THAN WHAT

919
00:36:29,700 --> 00:36:33,737
WAS THE GOAL OF 25, WHICH -- AND

920
00:36:33,737 --> 00:36:38,442
THIS TELLS YOU WHICH ARE THE

921
00:36:38,442 --> 00:36:39,443
MOST FREQUENTLY EXPOSED.

922
00:36:39,443 --> 00:36:41,278
AS YOU CAN SEE, THE MOST

923
00:36:41,278 --> 00:36:43,247
FREQUENTLY EXPOSED COME FROM

924
00:36:43,247 --> 00:36:45,682
ALCOHOL, AND IT IS ALL FOLLOWED

925
00:36:45,682 --> 00:36:47,284
BY -- ACTUALLY BY MARIJUANA, AND

926
00:36:47,284 --> 00:36:50,053
THEN TOBACCO.

927
00:36:50,053 --> 00:36:52,222
AND THEN WE HAVE 4% OF THEM ARE

928
00:36:52,222 --> 00:36:53,757
ACTUALLY ON OPIOIDS.

929
00:36:53,757 --> 00:36:57,895
AND IT ALSO HIGHLIGHTS THAT

930
00:36:57,895 --> 00:37:00,497
EXPOSURES ARE VERY MUCH MORE

931
00:37:00,497 --> 00:37:03,267
LIKELY TO BE POLYSUBSTANCE THAN

932
00:37:03,267 --> 00:37:04,802
A SINGLE SUBSTANCE.

933
00:37:04,802 --> 00:37:06,770
AGAIN, THE PLAN JUST LIKE IT WAS

934
00:37:06,770 --> 00:37:08,539
FOR ABCD IS TO ACTUALLY RELEASE

935
00:37:08,539 --> 00:37:10,474
THE DATA IN AN OPEN ACCESS

936
00:37:10,474 --> 00:37:13,010
FORMAT, SO THAT RESEARCHERS CAN

937
00:37:13,010 --> 00:37:14,344
START TO INVESTIGATE AND TAKE

938
00:37:14,344 --> 00:37:18,415
ADVANTAGE OF THIS TO ADVANCE THE

939
00:37:18,415 --> 00:37:21,652
SCIENCE AND OUR DEADLINE RIGHT

940
00:37:21,652 --> 00:37:25,155
NOW, OUR GOAL, IS TO, BY THE END

941
00:37:25,155 --> 00:37:29,092
OF 2024, HAVE A FULL RELEASE FOR

942
00:37:29,092 --> 00:37:30,961
THE FIRST DATASET FOR ABCD, SO

943
00:37:30,961 --> 00:37:33,030
THIS IS QUITE EXCITING.

944
00:37:33,030 --> 00:37:36,667
AND WITH THAT, HE WA I WANT TO P

945
00:37:36,667 --> 00:37:39,102
INTO THE BIG ELEPHANT IN THE

946
00:37:39,102 --> 00:37:41,572
ROOM OF WHAT HAS BEEN HAPPENING

947
00:37:41,572 --> 00:37:43,106
IN OUR COUNTRY WITH THE OVERDOSE

948
00:37:43,106 --> 00:37:47,478
CRISIS AND THE HOCIA HORRIBLE

949
00:37:47,478 --> 00:37:49,012
MORTALITY THAT IT IMPOSED AND

950
00:37:49,012 --> 00:37:50,614
THE SUFFERING IT MEANS FOR

951
00:37:50,614 --> 00:37:51,315
FAMILIES, FRIENDS AND

952
00:37:51,315 --> 00:37:51,615
COMMUNITIES.

953
00:37:51,615 --> 00:37:54,918
AND THE PROBLEM, UNFORTUNATELY,

954
00:37:54,918 --> 00:37:57,855
EVEN THOUGH THERE HAS BEEN VERY

955
00:37:57,855 --> 00:37:58,956
INTEGRATED EFFORTS TO FIGHT IT

956
00:37:58,956 --> 00:38:02,459
AND RESOURCES, IT CONTINUES TO

957
00:38:02,459 --> 00:38:06,296
GROW, ALBEIT IT IS GROWING AT A

958
00:38:06,296 --> 00:38:07,264
SLOWER PACE.

959
00:38:07,264 --> 00:38:08,999
THE NUMBERS WE HAVE WHICH

960
00:38:08,999 --> 00:38:10,567
CORRESPOND TO THE LAST 12 MONTHS

961
00:38:10,567 --> 00:38:12,636
THAT ENDED IN JULY 2023

962
00:38:12,636 --> 00:38:17,574
INDICATED THAT THERE WERE

963
00:38:17,574 --> 00:38:19,409
111,964 PEOPLE THAT DIED FROM AN

964
00:38:19,409 --> 00:38:22,813
OVERDOSE THAT YEAR, AND THAT'S

965
00:38:22,813 --> 00:38:23,580
2.3% INCREASE FROM THE PRIOR

966
00:38:23,580 --> 00:38:27,951
YEAR.

967
00:38:27,951 --> 00:38:29,720
YES, THIS IS AN INCREASE, BUT AS

968
00:38:29,720 --> 00:38:31,321
I SAY, IT'S SIGNIFICANTLY LOWER

969
00:38:31,321 --> 00:38:35,959
THAN WHAT WE SAW IN 2020, WHEN

970
00:38:35,959 --> 00:38:37,594
THE INCREASE DURING THE COVID

971
00:38:37,594 --> 00:38:39,663
PANDEMIC WAS 30%, AND THEN THE

972
00:38:39,663 --> 00:38:43,033
NEXT YEAR, ON 2021, IT WAS 15%.

973
00:38:43,033 --> 00:38:45,702
SO IT HAS SLOWED DOWN, BUT IT

974
00:38:45,702 --> 00:38:47,004
HASN'T BASICALLY DECREASED AND

975
00:38:47,004 --> 00:38:50,507
IT CONTINUES TO INCREASE, AND SO

976
00:38:50,507 --> 00:38:52,142
IT'S AT VERY, VERY HIGH LEVELS.

977
00:38:52,142 --> 00:38:55,546
WE ARE ALSO MONITORING THE PATH

978
00:38:55,546 --> 00:38:57,180
OF WHAT'S HAPPENING, WE HAVE

979
00:38:57,180 --> 00:38:58,515
BEEN SEEING THAT FOR SEVERAL

980
00:38:58,515 --> 00:39:00,717
YEARS, THAT OVERDOSES FROM

981
00:39:00,717 --> 00:39:01,885
HEROIN HAVE BEEN GOING DOWN.

982
00:39:01,885 --> 00:39:04,855
WE'VE ALSO BEEN SEEING THAT THE

983
00:39:04,855 --> 00:39:07,024
OVERDOSES -- FATALITIES FROM

984
00:39:07,024 --> 00:39:08,792
PAIN MEDICATIONS THAT CONTAIN

985
00:39:08,792 --> 00:39:09,993
OPIATES HAVE BEEN GOING DOWN,

986
00:39:09,993 --> 00:39:13,897
AND WE'VE ALSO BEEN SEEING THAT

987
00:39:13,897 --> 00:39:14,831
FATALITIES FROM METHADONE HAVE

988
00:39:14,831 --> 00:39:16,266
BEEN GOING DOWN.

989
00:39:16,266 --> 00:39:18,769
BUT WE HAVE BEEN SEEING THE MAIN

990
00:39:18,769 --> 00:39:20,504
CULPRIT, FENTANYL, AND JUST LOOK

991
00:39:20,504 --> 00:39:23,140
AT THE NUMBERS OF PEOPLE THAT

992
00:39:23,140 --> 00:39:26,777
OVERDOSE AND DIE FROM FENTANYL

993
00:39:26,777 --> 00:39:28,211
ARE THE DRIVERS, AND THEY

994
00:39:28,211 --> 00:39:29,279
CONTINUE TO INCREASE.

995
00:39:29,279 --> 00:39:30,514
NOW, AS YOU LOOK TO THE RIGHT,

996
00:39:30,514 --> 00:39:33,016
WE HAVE THE STIMULANT DRUGS,

997
00:39:33,016 --> 00:39:35,652
COCAINE AND METHAMPHETAMINE, AND

998
00:39:35,652 --> 00:39:37,387
WHEN YOU LOOK AT THE NUMBERS YOU

999
00:39:37,387 --> 00:39:38,722
SAY IT'S VERY CLOSE TO FENTANYL,

1000
00:39:38,722 --> 00:39:40,324
AND THAT IS CORRECT, EXCEPT THAT

1001
00:39:40,324 --> 00:39:41,725
THE ISSUE THAT WE NEED TO

1002
00:39:41,725 --> 00:39:44,661
UNDERSTAND IS THAT MOST OF THESE

1003
00:39:44,661 --> 00:39:48,231
DEATHS, THESE 66 OR CLOSE TO

1004
00:39:48,231 --> 00:39:50,100
67,000 PEOPLE DYING FROM

1005
00:39:50,100 --> 00:39:51,835
PSYCHOSTIMULANTS, THE MAJORITY

1006
00:39:51,835 --> 00:39:55,272
OF THEM ACTUALLY HAD ALSO

1007
00:39:55,272 --> 00:39:56,306
FENTANYL.

1008
00:39:56,306 --> 00:39:58,108
SO IT IS A VERY FREQUENT

1009
00:39:58,108 --> 00:40:00,077
PATTERN, THAT OF SEEING OTHER

1010
00:40:00,077 --> 00:40:02,579
DRUGS ACTUALLY IN COMBINATION

1011
00:40:02,579 --> 00:40:05,115
WITH FENTANYL, WHICH THEN

1012
00:40:05,115 --> 00:40:06,750
INCREASES THE LETHALITY OF THESE

1013
00:40:06,750 --> 00:40:08,085
DRUGS AS WE'RE SEEING FOR

1014
00:40:08,085 --> 00:40:10,253
COCAINE, WHERE WE SAW A 12.2%

1015
00:40:10,253 --> 00:40:12,556
INCREASE IN MORTALITY, AND A

1016
00:40:12,556 --> 00:40:15,626
6.4% FOR METHAMPHETAMINE.

1017
00:40:15,626 --> 00:40:18,028
SO THESE HAS MADE ACTUALLY

1018
00:40:18,028 --> 00:40:20,764
ADDRESSING THE OVERDOSES AND THE

1019
00:40:20,764 --> 00:40:22,633
PROTECTION AND THE PREVENTION OF

1020
00:40:22,633 --> 00:40:25,936
THESE OVERDOSES MUCH MORE

1021
00:40:25,936 --> 00:40:27,137
COMPLEX, BECAUSE IT'S NOT NOW

1022
00:40:27,137 --> 00:40:29,206
ONLY PEOPLE THAT ARE SEEKING

1023
00:40:29,206 --> 00:40:31,074
OPIOIDS THAT ARE DYING, BUT ALSO

1024
00:40:31,074 --> 00:40:35,879
PEOPLE THAT ARE SEEKING OUT

1025
00:40:35,879 --> 00:40:37,414
COCAINE AND METHAMPHETAMINE.

1026
00:40:37,414 --> 00:40:38,749
SO WE KNOW THAT ALL ALONG

1027
00:40:38,749 --> 00:40:40,717
ACTUALLY THAT ONE OF THE MOST

1028
00:40:40,717 --> 00:40:45,622
POWERFUL TOOLS THAT WE HAVE FOR

1029
00:40:45,622 --> 00:40:46,957
ADDRESSING THE OVERDOSE CRISIS

1030
00:40:46,957 --> 00:40:48,492
IS ACCESS TO TREATMENT.

1031
00:40:48,492 --> 00:40:50,360
THIS BECAME VERY, VERY EVIDENT

1032
00:40:50,360 --> 00:40:52,095
AND URGENT DURING THE COVID

1033
00:40:52,095 --> 00:40:54,297
PANDEMIC, WHEN THE SOCIETY

1034
00:40:54,297 --> 00:40:56,900
CLOSED, AND THAT FORCED

1035
00:40:56,900 --> 00:40:58,568
BASICALLY CHANGING THE PATTERN

1036
00:40:58,568 --> 00:41:01,605
BY WHICH WE WERE DEPLOYING THE

1037
00:41:01,605 --> 00:41:04,141
TREATMENTS FOR OPIOID USE

1038
00:41:04,141 --> 00:41:07,044
DISORDER, MOST NOTELY METHADONE

1039
00:41:07,044 --> 00:41:10,480
TO THE OPIATE OR METHADONE M

1040
00:41:10,480 --> 00:41:13,784
PRAS, AND BUPRENORPHINE, TO

1041
00:41:13,784 --> 00:41:16,253
ACTUALLY RELAX THE PROCEDURE SO

1042
00:41:16,253 --> 00:41:17,721
IT WOULD MAKE IT EASIER FOR

1043
00:41:17,721 --> 00:41:19,022
PEOPLE TO ACCESS THESE

1044
00:41:19,022 --> 00:41:21,892
MEDICATIONS AND TO STAY IN THESE

1045
00:41:21,892 --> 00:41:24,194
MEDICATIONS.

1046
00:41:24,194 --> 00:41:25,295
AND FROM THE EXPERIENCE WITH THE

1047
00:41:25,295 --> 00:41:27,030
COVID PANDEMIC, IT BECAME CLEAR

1048
00:41:27,030 --> 00:41:31,535
THAT, YES, DECREASING THE

1049
00:41:31,535 --> 00:41:33,270
RESTRICTIVENESS OF PROVIDEING

1050
00:41:33,270 --> 00:41:34,805
WITH METHADONE IN OPIATE

1051
00:41:34,805 --> 00:41:37,674
TREATMENT PROGRAMS BASICALLY

1052
00:41:37,674 --> 00:41:39,976
INCREASED ACCESS TO METHADONE

1053
00:41:39,976 --> 00:41:41,278
AND DID NOT RESULT IN AN

1054
00:41:41,278 --> 00:41:44,147
INCREASE IN PEOPLE DYING FROM

1055
00:41:44,147 --> 00:41:46,116
OVERDOSES FROM METHADONE AS

1056
00:41:46,116 --> 00:41:47,851
INITIALLY WAS -- PEOPLE HAD BEEN

1057
00:41:47,851 --> 00:41:48,218
AFRAID.

1058
00:41:48,218 --> 00:41:53,590
AND SIMILARLY, THE RELAXATION OF

1059
00:41:53,590 --> 00:41:55,425
PROVIDING WITH BUPRENORPHINE

1060
00:41:55,425 --> 00:41:56,426
TREATMENT FOR THOSE THAT NEEDED

1061
00:41:56,426 --> 00:41:59,496
IT WAS ALSO ASSOCIATED WITH NEW

1062
00:41:59,496 --> 00:42:01,131
INITIATE AND INCREASED

1063
00:42:01,131 --> 00:42:02,132
SUSTAINMENT IN TREATMENT.

1064
00:42:02,132 --> 00:42:05,736
SO IT IS VERY EXCITING FOR ME TO

1065
00:42:05,736 --> 00:42:09,573
BRING FORWARD THE NEW FEDERAL

1066
00:42:09,573 --> 00:42:11,675
REGISTER WHERE IT ACTUALLY IS

1067
00:42:11,675 --> 00:42:13,076
ANNOUNCED TARGETING CHANGES TO

1068
00:42:13,076 --> 00:42:14,611
THE MEDICATION FOR THE TREATMENT

1069
00:42:14,611 --> 00:42:17,581
OF OPIOID USE DISORDER IN WHICH

1070
00:42:17,581 --> 00:42:20,851
IT ELIMINATES ONE YEAR OPIOID

1071
00:42:20,851 --> 00:42:23,854
ADDICTION HISTORY REQUIREMENT BY

1072
00:42:23,854 --> 00:42:26,990
THE OTPs IN ORDER TO BE ABLE

1073
00:42:26,990 --> 00:42:29,226
TO GIVE TREATMENT TO PREGNANT

1074
00:42:29,226 --> 00:42:30,727
INDIVIDUALS.

1075
00:42:30,727 --> 00:42:35,098
IT ALSO INCORPORATES --

1076
00:42:35,098 --> 00:42:36,166
REDUCTION PRINCIPLES INTO

1077
00:42:36,166 --> 00:42:37,267
TREATMENT, WHICH IS THE FIRST

1078
00:42:37,267 --> 00:42:40,737
TIME WE'VE SEEN THIS AS ONE OF

1079
00:42:40,737 --> 00:42:45,408
THE ITEMS THAT IS PROMOTED.

1080
00:42:45,408 --> 00:42:47,210
IT REMOVES THE REQUIREMENTS FOR

1081
00:42:47,210 --> 00:42:51,348
TWO DOCUMENTED INSTANCES OF

1082
00:42:51,348 --> 00:42:52,115
UNSUCCESSFUL TREATMENT FOR

1083
00:42:52,115 --> 00:42:54,951
PEOPLE UNDER AGE 18, SO THAT

1084
00:42:54,951 --> 00:42:56,086
THEY CAN ALSO BENEFIT FROM THE

1085
00:42:56,086 --> 00:42:58,121
USE OF MEDICATIONS FOR OPIOID

1086
00:42:58,121 --> 00:42:59,890
USE DISORDER IF THEY ARE

1087
00:42:59,890 --> 00:43:04,361
TEENAGERS AND REQUIRE THEM.

1088
00:43:04,361 --> 00:43:07,564
AND THE MEDICATION ACCESS IS NO

1089
00:43:07,564 --> 00:43:08,965
LONGER CONTINGENT ON COUNSELING,

1090
00:43:08,965 --> 00:43:10,600
WHICH WAS AN ISSUE THAT MADE IT

1091
00:43:10,600 --> 00:43:11,501
VERY HARD SOMETIMES TO PROVIDE

1092
00:43:11,501 --> 00:43:15,005
FOR METHADONE EXCEPT IN

1093
00:43:15,005 --> 00:43:16,072
METHADONE OPIOID TREATMENT

1094
00:43:16,072 --> 00:43:16,406
PROGRAMS.

1095
00:43:16,406 --> 00:43:17,707
IT ALSO ALLOWS FOR THE SCREENING

1096
00:43:17,707 --> 00:43:20,177
TO BE PERFORMED BY PRACTITIONERS

1097
00:43:20,177 --> 00:43:22,913
OUTSIDE THE OPIATE TREATMENT

1098
00:43:22,913 --> 00:43:24,781
PROGRAMS, AND THE COVID-19

1099
00:43:24,781 --> 00:43:27,851
TAKE-HOME FLEXIBILITIES MADE

1100
00:43:27,851 --> 00:43:28,718
PERMANENT -- WERE MADE

1101
00:43:28,718 --> 00:43:30,153
PERMANENT, INCLUDING BEING ABLE

1102
00:43:30,153 --> 00:43:32,789
TO TAKE METHADONE HOME WITHIN

1103
00:43:32,789 --> 00:43:34,291
ONE WEEK OF TREATMENT UNDER

1104
00:43:34,291 --> 00:43:39,462
CERTAIN CONDITIONS.

1105
00:43:39,462 --> 00:43:41,631
IT ALSO ALLOWS FOR SCREENING FOR

1106
00:43:41,631 --> 00:43:46,570
BUPRENORPHINE INITIATION FOR

1107
00:43:46,570 --> 00:43:53,476
AUDIO ONLY OR AUDIO-VISUAL

1108
00:43:53,476 --> 00:43:54,678
TELEHEALTH UNDER CERTAIN

1109
00:43:54,678 --> 00:43:57,514
CONDITION AND ALLOWS ANY

1110
00:43:57,514 --> 00:44:00,050
QUALIFYING OPIATE TREATMENT

1111
00:44:00,050 --> 00:44:01,151
PROGRAM, THE TIME FRAME WAS

1112
00:44:01,151 --> 00:44:02,786
EXPANDED FROM 120 TO 180 DAYS.

1113
00:44:02,786 --> 00:44:05,555
AND FINALLY, IT ALLOWS NURSE

1114
00:44:05,555 --> 00:44:06,990
PRACTITIONERS AND PHYSICIAN

1115
00:44:06,990 --> 00:44:08,825
ASSISTANTS TO ORDER MEDICATIONS

1116
00:44:08,825 --> 00:44:12,996
FOR OPIOID USE DISORDER FOR

1117
00:44:12,996 --> 00:44:13,964
OPIATE TREATMENT DISPENSING.

1118
00:44:13,964 --> 00:44:16,499
SO ALL OF THESE CHANGES ARE

1119
00:44:16,499 --> 00:44:18,568
BASICALLY CONSOLIDATING

1120
00:44:18,568 --> 00:44:20,437
PRACTICES THAT WILL MAKE IT MUCH

1121
00:44:20,437 --> 00:44:21,438
EASIER FOR PEOPLE TO HAVE ACCESS

1122
00:44:21,438 --> 00:44:23,440
TO TREATMENT, WHICH, AGAIN, IS

1123
00:44:23,440 --> 00:44:24,741
CRUCIAL BECAUSE WE KNOW THAT THE

1124
00:44:24,741 --> 00:44:28,345
MOST POWERFUL TOOL THAT WE HAVE

1125
00:44:28,345 --> 00:44:30,513
TO PREVENT OVERDOSES IS GIVING

1126
00:44:30,513 --> 00:44:32,182
ACCESS TO MEDICATIONS FOR OPIOID

1127
00:44:32,182 --> 00:44:33,283
USE DISORDER TO THOSE THAT NEED

1128
00:44:33,283 --> 00:44:38,355
THEM.

1129
00:44:38,355 --> 00:44:40,123
SO YES, AND THIS IS VERY MUCH

1130
00:44:40,123 --> 00:44:42,325
DESCRIBED IN THE HHS OVERDOSE

1131
00:44:42,325 --> 00:44:43,526
PREVENTION STRATEGY.

1132
00:44:43,526 --> 00:44:44,594
EVIDENCE-BASED TREATMENT

1133
00:44:44,594 --> 00:44:46,029
HIGHLIGHTS THE IMPORTANCE OF

1134
00:44:46,029 --> 00:44:48,031
MEDICATIONS FOR OPIATE USE

1135
00:44:48,031 --> 00:44:49,666
DISORDER, BUT ALSO EXPANDED

1136
00:44:49,666 --> 00:44:52,269
ACCESS FOR NALOXONE.

1137
00:44:52,269 --> 00:44:55,238
BUT ALSO NOW IN THIS NEW

1138
00:44:55,238 --> 00:44:56,773
ADMINISTRATION, IT HAS

1139
00:44:56,773 --> 00:44:58,108
HIGHLIGHTED, THE HHS, THE

1140
00:44:58,108 --> 00:45:00,744
IMPORTANCE OF HARM REDUCTION

1141
00:45:00,744 --> 00:45:02,579
APPROACHES AS A STRATEGY IN

1142
00:45:02,579 --> 00:45:03,914
ORDER TO PREVENT OVERDOSE

1143
00:45:03,914 --> 00:45:04,781
DEATHS.

1144
00:45:04,781 --> 00:45:07,217
AND THIS IS CRUCIAL BECAUSE

1145
00:45:07,217 --> 00:45:10,720
WHILE OBVIOUSLY THE IDEAL IS TO

1146
00:45:10,720 --> 00:45:12,122
GET PEOPLE INTO TREATMENT AND

1147
00:45:12,122 --> 00:45:13,556
ULTIMATELY INTO FULL RECOVERY,

1148
00:45:13,556 --> 00:45:16,092
THE REALITY IS THAT THERE ARE

1149
00:45:16,092 --> 00:45:17,627
MANY INDIVIDUALS WHO ARE TAKING

1150
00:45:17,627 --> 00:45:19,362
DRUGS THAT ARE NOT READY TO GET

1151
00:45:19,362 --> 00:45:25,068
INTO TREATMENT AND NOT OFFERING

1152
00:45:25,068 --> 00:45:26,169
SOME OF THE INTERVENTIONS THAT

1153
00:45:26,169 --> 00:45:28,271
COULD SAVE THEIR LIVES.

1154
00:45:28,271 --> 00:45:30,106
ACTUALLY INTERFERES WITH THEIR

1155
00:45:30,106 --> 00:45:31,675
GIVING THEM AN OPPORTUNITY TO

1156
00:45:31,675 --> 00:45:34,344
EVENTUALLY GET INTO RECOVERY.

1157
00:45:34,344 --> 00:45:38,081
SO HARM REDUCTION AIMS TO

1158
00:45:38,081 --> 00:45:38,949
PROVIDE SUPPORT TO PEOPLE WHERE

1159
00:45:38,949 --> 00:45:39,616
THEY ARE.

1160
00:45:39,616 --> 00:45:42,585
IF IT IS HELPING THEM GUIDE THEM

1161
00:45:42,585 --> 00:45:45,555
INTO TREATMENT, IT IS BASICALLY

1162
00:45:45,555 --> 00:45:47,290
HELP THEM, GUIDE THEM IN HOW TO

1163
00:45:47,290 --> 00:45:51,227
USE DRUGS IN A WAY THAT IS LESS

1164
00:45:51,227 --> 00:45:52,796
HARMFUL THEN, AND THEN STABILIZE

1165
00:45:52,796 --> 00:45:55,532
THEM AND THEN GIVING THEM AN

1166
00:45:55,532 --> 00:45:57,400
OPPORTUNITY TO BE READY

1167
00:45:57,400 --> 00:45:59,369
EVENTUALLY TO GO INTO TREATMENT,

1168
00:45:59,369 --> 00:46:00,236
THEN WE SHOULD DO IT.

1169
00:46:00,236 --> 00:46:04,074
WE SHOULD BE ABLE TO PROVIDE AND

1170
00:46:04,074 --> 00:46:07,043
PROTECT PEOPLE FROM DYING FROM

1171
00:46:07,043 --> 00:46:10,013
OVERDOSES.

1172
00:46:10,013 --> 00:46:10,981
IN THE FIELD OF HARM REDUCTION

1173
00:46:10,981 --> 00:46:12,315
AND IN THE RESEARCH OF HARM

1174
00:46:12,315 --> 00:46:13,049
REDUCTION, THERE ARE SOME

1175
00:46:13,049 --> 00:46:14,617
PRACTICES THAT HAVE BEEN

1176
00:46:14,617 --> 00:46:15,285
EXTENSIVELY INVESTIGATED.

1177
00:46:15,285 --> 00:46:18,221
AND I WILL SAY THE MOST NOTABLE

1178
00:46:18,221 --> 00:46:20,390
AND MOST WIDESPREAD RESEARCH HAS

1179
00:46:20,390 --> 00:46:23,159
BEEN DONE ON SYRINGE EXCHANGES

1180
00:46:23,159 --> 00:46:24,794
AND SYRINGE SERVICES PROGRAMS.

1181
00:46:24,794 --> 00:46:28,732
AND THE RESEARCH IS BASICALLY

1182
00:46:28,732 --> 00:46:32,569
CLEARCUT SHOWING THAT SYRINGE

1183
00:46:32,569 --> 00:46:33,703
EXCHANGE AND SYRINGE SERVICES

1184
00:46:33,703 --> 00:46:36,106
PROGRAMS ACTUALLY ARE VERY

1185
00:46:36,106 --> 00:46:40,810
EFFECTIVE IN PROTECTING PEOPLE

1186
00:46:40,810 --> 00:46:42,679
FROM INFECTIOUS DISEASES, HIV,

1187
00:46:42,679 --> 00:46:43,213
HCV.

1188
00:46:43,213 --> 00:46:45,181
IT'S ALSO SHOWN THAT IT HELPS

1189
00:46:45,181 --> 00:46:46,716
PEOPLE LINK THEM WITH TREATMENT,

1190
00:46:46,716 --> 00:46:52,322
AND IT ALSO HAS SHOWN THAT IT --

1191
00:46:52,322 --> 00:46:54,491
OPIATE USE DISORDER LU ALSO LINK

1192
00:46:54,491 --> 00:46:56,259
THEM FOR TREATMENT FOR OTHER

1193
00:46:56,259 --> 00:46:57,994
MEDICAL CONDITIONS AND, BY THE

1194
00:46:57,994 --> 00:46:59,329
WAY, IT'S COST-EFFECTIVE.

1195
00:46:59,329 --> 00:47:00,764
SO THERE'S NO MORE RESEARCH

1196
00:47:00,764 --> 00:47:01,731
NEEDED TO SHOW THAT IT IS

1197
00:47:01,731 --> 00:47:02,298
EFFECTIVE.

1198
00:47:02,298 --> 00:47:04,601
THE ISSUE, THOUGH, THAT IS VERY

1199
00:47:04,601 --> 00:47:05,702
FRUSTRATING IS DESPITE THIS

1200
00:47:05,702 --> 00:47:06,669
EVIDENCE, WHY IS IT THAT THEY

1201
00:47:06,669 --> 00:47:08,671
ARE NOT IMPLEMENTED?

1202
00:47:08,671 --> 00:47:10,673
WHY IS IT THAT THERE ARE SO MANY

1203
00:47:10,673 --> 00:47:13,710
PLACES THAT ARE STILL BASICALLY

1204
00:47:13,710 --> 00:47:16,913
CLOSED SYRINGE EXCHANGE PROGRAMS

1205
00:47:16,913 --> 00:47:20,316
WITH THE CONSEQUENCES AS CAN BE

1206
00:47:20,316 --> 00:47:23,153
EXPECTED OF BASICALLY NEW CASES

1207
00:47:23,153 --> 00:47:27,657
OF INFECTIONS THAT HAPPEN WHEN

1208
00:47:27,657 --> 00:47:28,525
THIS HAS A CURE.

1209
00:47:28,525 --> 00:47:30,260
SO FROM THAT PERSPECTIVE ON

1210
00:47:30,260 --> 00:47:32,695
RESEARCH, THE QUESTION THAT

1211
00:47:32,695 --> 00:47:37,967
LINGERS IS WHAT NEEDS TO BE DONE

1212
00:47:37,967 --> 00:47:39,402
TO ACTUALLY MODIFY PRACTICES SO

1213
00:47:39,402 --> 00:47:41,805
THAT THERE IS IMPLEMENTATION OF

1214
00:47:41,805 --> 00:47:42,739
THIS VERY STRONG EVIDENCE

1215
00:47:42,739 --> 00:47:43,406
INITIATIVE.

1216
00:47:43,406 --> 00:47:45,542
THERE IS ALSO VERY STRONG

1217
00:47:45,542 --> 00:47:47,310
EVIDENCE THAT DISTRIBUTION OF

1218
00:47:47,310 --> 00:47:49,612
NALOXONE, WHICH IS THE OPIOID

1219
00:47:49,612 --> 00:47:50,847
RECEPTOR ANTAGONIST DRUGS THAT

1220
00:47:50,847 --> 00:47:53,450
WHEN APPLIED IN TIME CAN

1221
00:47:53,450 --> 00:47:55,218
BASICALLY SAVE A LIFE, I LIKE TO

1222
00:47:55,218 --> 00:47:56,786
CALL IT A MIRACLE DRUG, AND I

1223
00:47:56,786 --> 00:47:58,221
DON'T LIKE TO CALL ANYTHING

1224
00:47:58,221 --> 00:48:00,390
MIRACLE, BUT THE REALITY IS

1225
00:48:00,390 --> 00:48:01,825
NALOXONE, I CALL IT A MIRACLE

1226
00:48:01,825 --> 00:48:03,359
BECAUSE IF YOU DO GIVE IT IN

1227
00:48:03,359 --> 00:48:04,661
TIME AT THE CORRECT DOSE, YOU

1228
00:48:04,661 --> 00:48:06,229
WILL SAVE A PERSON'S LIFE.

1229
00:48:06,229 --> 00:48:08,298
AND IT HAS MINIMAL NEGATIVE

1230
00:48:08,298 --> 00:48:09,499
EFFECTS, SIDE EFFECTS.

1231
00:48:09,499 --> 00:48:11,234
SO IF YOU GIVE IT AND SOMEONE

1232
00:48:11,234 --> 00:48:12,602
HAS AN OVERDOSE FROM SOMETHING

1233
00:48:12,602 --> 00:48:13,703
ELSE, YOU ARE NOT GOING TO HARM

1234
00:48:13,703 --> 00:48:15,438
THEM.

1235
00:48:15,438 --> 00:48:19,976
BUT THERE IS BASICALLY

1236
00:48:19,976 --> 00:48:21,244
ABSOLUTELY SPACE TO DO RESEARCH

1237
00:48:21,244 --> 00:48:22,245
TO UNDERSTAND, FOR EXAMPLE, WHAT

1238
00:48:22,245 --> 00:48:24,647
ARE THE OPTIMAL DISTRIBUTION

1239
00:48:24,647 --> 00:48:25,515
STRATEGIES, WHAT IS THE PATTERN

1240
00:48:25,515 --> 00:48:33,957
OF USE IN TERMS OF DOSING, AND

1241
00:48:33,957 --> 00:48:34,958
WHO -- POCKETS OF PEOPLE THAT

1242
00:48:34,958 --> 00:48:36,593
ARE VERY VULNERABLE THAT ARE NOT

1243
00:48:36,593 --> 00:48:38,228
GETTING ACCESS TO NALOXONE IN

1244
00:48:38,228 --> 00:48:40,463
ORDER TO BE ABLE TO IDENTIFY

1245
00:48:40,463 --> 00:48:41,331
THEM AND ADDRESS IT.

1246
00:48:41,331 --> 00:48:43,333
AND THERE ARE OTHER AREAS FOR

1247
00:48:43,333 --> 00:48:44,434
WHICH HARM REDUCTION PRACTICES

1248
00:48:44,434 --> 00:48:49,672
HAVE BEEN STUDIED LESS.

1249
00:48:49,672 --> 00:48:50,874
OVERDOSE PREVENTION SENATORS,

1250
00:48:50,874 --> 00:48:53,743
MOST OF THE RESEARCH HAS BEEN

1251
00:48:53,743 --> 00:48:55,278
DONE IN STUDIES OUTSIDE THE

1252
00:48:55,278 --> 00:48:57,046
UNITED STATES AND BECAUSE OF THE

1253
00:48:57,046 --> 00:48:57,947
SUCCESS OF THESE PROGRAMS WHICH

1254
00:48:57,947 --> 00:48:59,682
HAVE BEEN SHOWN THERE'S NO TWO

1255
00:48:59,682 --> 00:49:01,784
WAYS AROUND IT, THEY SAVE LIVES,

1256
00:49:01,784 --> 00:49:06,823
BUT THEY ACTUALLY ARE MEASURED

1257
00:49:06,823 --> 00:49:08,791
AGAINST WHAT THE OUTCOMES WILL

1258
00:49:08,791 --> 00:49:11,327
BE ACHIEVED BECAUSE THESE

1259
00:49:11,327 --> 00:49:12,562
REQUIRE RESOURCES, AND UNDER

1260
00:49:12,562 --> 00:49:14,230
WHAT CONDITIONS AND CONTEXT THEY

1261
00:49:14,230 --> 00:49:15,298
ARE MOST VALUABLE.

1262
00:49:15,298 --> 00:49:18,168
THAT RESEARCH IS NEEDED IN OUR

1263
00:49:18,168 --> 00:49:22,071
COUNTRY.

1264
00:49:22,071 --> 00:49:23,306
SIMILARLY AS WE'RE SEEING MORE

1265
00:49:23,306 --> 00:49:24,741
AND MORE FENTANYL USED TO LACE

1266
00:49:24,741 --> 00:49:28,344
OTHER DRUGS, CONTAMINATING THEM,

1267
00:49:28,344 --> 00:49:31,681
THE POSSIBILITY OF GIVING TEST

1268
00:49:31,681 --> 00:49:32,749
STRIPS FOR INDIVIDUALS THAT ARE

1269
00:49:32,749 --> 00:49:34,350
USING DRUGS SO THEY CAN TEST THE

1270
00:49:34,350 --> 00:49:37,153
DRUGS BEFORE THEY USE THEM HAS

1271
00:49:37,153 --> 00:49:39,022
GENERATED A LOT OF INTEREST IN

1272
00:49:39,022 --> 00:49:39,923
SOME STATES.

1273
00:49:39,923 --> 00:49:42,859
THEY ACTUALLY -- DOLLARS CAN BE

1274
00:49:42,859 --> 00:49:44,160
USED FROM THE STATES IN ORDER TO

1275
00:49:44,160 --> 00:49:46,629
PURCHASE THOSE TEST STRIPS IN

1276
00:49:46,629 --> 00:49:47,497
OTHER STATES.

1277
00:49:47,497 --> 00:49:49,799
THEY ARE STILL CONSIDERED DRUG

1278
00:49:49,799 --> 00:49:50,867
PARAPHERNALIA AND, THEREFORE,

1279
00:49:50,867 --> 00:49:52,835
ILLEGAL.

1280
00:49:52,835 --> 00:49:54,504
SO RESEARCH IS NEEDED TO TRY TO

1281
00:49:54,504 --> 00:49:57,340
UNDERSTAND HOW TO OPTIMALLY

1282
00:49:57,340 --> 00:49:58,641
DISSEMINATE AND IMPLEMENT THE

1283
00:49:58,641 --> 00:50:01,211
USE OF THESE TEST STRIPS,

1284
00:50:01,211 --> 00:50:03,846
WHETHER IT IS FOR FENTANYL AND

1285
00:50:03,846 --> 00:50:05,381
XYLAZINE, AND HOW TO EDUCATE THE

1286
00:50:05,381 --> 00:50:07,150
USERS IF THEY DO HAVE POSITIVE

1287
00:50:07,150 --> 00:50:09,052
TESTS ON HOW TO ACTUALLY

1288
00:50:09,052 --> 00:50:11,854
MINIMIZE THE RISKS IF THEY

1289
00:50:11,854 --> 00:50:16,492
DECIDE TO STILL USE THE DRUGS.

1290
00:50:16,492 --> 00:50:19,896
AND TO ME, I'VE PUT THESE OTHERS

1291
00:50:19,896 --> 00:50:21,531
BECAUSE OBVIOUSLY PEOPLE ARE

1292
00:50:21,531 --> 00:50:22,832
TRYING TO COME UP WITH DIFFERENT

1293
00:50:22,832 --> 00:50:26,736
TYPE OF STRATEGIES TO PREVENT

1294
00:50:26,736 --> 00:50:28,338
THEM FROM GOING INTO WITHDRAWAL,

1295
00:50:28,338 --> 00:50:31,741
FOR EXAMPLE, THE UTILIZATION IN

1296
00:50:31,741 --> 00:50:33,676
SOME INSTANCES OF CANNABIS, AND

1297
00:50:33,676 --> 00:50:35,712
FROM THAT PERSPECTIVE, THOSE CAN

1298
00:50:35,712 --> 00:50:39,983
ALSO BE DESCRIBED IN HARM

1299
00:50:39,983 --> 00:50:41,551
REDUCTION PRACTICES, BUT THERE

1300
00:50:41,551 --> 00:50:42,986
IS VERY LITTLE RESEARCH IN THAT

1301
00:50:42,986 --> 00:50:47,423
RESPECT.

1302
00:50:47,423 --> 00:50:49,626
SO TO TRY TO ADDRESS BASICALLY

1303
00:50:49,626 --> 00:50:50,960
AND PUSH FORWARD THE CONCEPT OF

1304
00:50:50,960 --> 00:50:54,130
THE NEED FOR RESEARCH ON HARM

1305
00:50:54,130 --> 00:50:57,300
REDUCTION, LAST YEAR WE

1306
00:50:57,300 --> 00:50:59,302
BASICALLY DEPLOYED A HARM

1307
00:50:59,302 --> 00:51:01,037
REDUCTION RESEARCH NETWORK THAT

1308
00:51:01,037 --> 00:51:03,139
AIMS TO BASICALLY INVESTIGATE

1309
00:51:03,139 --> 00:51:05,541
NOVEL HARM REDUCTION APPROACHES,

1310
00:51:05,541 --> 00:51:06,909
NOVEL SETTINGS FOR DEPLOYING

1311
00:51:06,909 --> 00:51:11,714
THOSE ARMORY D HARM REDUCTION A,

1312
00:51:11,714 --> 00:51:14,550
UNDERSTANDING WHAT ARE THE

1313
00:51:14,550 --> 00:51:23,026
BARRIERS, AND RESEARCHING

1314
00:51:23,026 --> 00:51:25,662
UNDERSTSTUDIED POPULATIONS.

1315
00:51:25,662 --> 00:51:26,863
THESE ARE ORGANIZED IN SUCH A

1316
00:51:26,863 --> 00:51:28,164
WAY THAT WE STARTED WITH 10

1317
00:51:28,164 --> 00:51:31,501
DIFFERENT GRANTS THAT ARE UNITED

1318
00:51:31,501 --> 00:51:32,702
THROUGH A COORDINATION CENTER

1319
00:51:32,702 --> 00:51:37,874
THAT IS COMPOSED OF FOUR CORES,

1320
00:51:37,874 --> 00:51:41,678
ONE FOR COMMUNICATION AND

1321
00:51:41,678 --> 00:51:42,779
COORDINATION, ONE FOR DATA

1322
00:51:42,779 --> 00:51:44,314
HARMONIZATION AND METHODOLOGY SO

1323
00:51:44,314 --> 00:51:45,515
THE DATA IS COLLECTED IN WAYS

1324
00:51:45,515 --> 00:51:47,750
THAT THEN CAN BE UTILIZED ACROSS

1325
00:51:47,750 --> 00:51:49,719
THE DIFFERENT INVESTIGATORS AND

1326
00:51:49,719 --> 00:51:50,787
OTHERS, COMMUNITY AND

1327
00:51:50,787 --> 00:51:52,488
STAKEHOLDER ENGAGEMENT, SO THAT

1328
00:51:52,488 --> 00:51:57,060
WE CAN BASICALLY HAVE A MUCH

1329
00:51:57,060 --> 00:51:58,161
MORE -- HAVE MUCH MORE

1330
00:51:58,161 --> 00:51:58,828
ENGAGEMENT OF THOSE PEOPLE THAT

1331
00:51:58,828 --> 00:52:01,798
ARE OUT THERE AND MOST

1332
00:52:01,798 --> 00:52:02,565
KNOWLEDGEABLE OF WHAT ARE SOME

1333
00:52:02,565 --> 00:52:04,200
OF THE CHALLENGES THAT THEY

1334
00:52:04,200 --> 00:52:05,868
FACE, AND IMPORTANTLY,

1335
00:52:05,868 --> 00:52:07,136
DISSEMINATION AND TRANSLATION.

1336
00:52:07,136 --> 00:52:10,306
SO THAT THE KNOWLEDGE CAN BE U 

1337
00:52:10,306 --> 00:52:12,375
USED BY OTHERS AND SO THAT IT

1338
00:52:12,375 --> 00:52:15,611
CAN ADVANCE IT FURTHER.

1339
00:52:15,611 --> 00:52:17,213
NOW, I'M GOING TO JUMP FROM THE

1340
00:52:17,213 --> 00:52:18,314
HARM REDUCTION TO THIS SLIDE,

1341
00:52:18,314 --> 00:52:24,220
WHICH I HAVE SHOWN IN THE PAST,

1342
00:52:24,220 --> 00:52:25,488
ACTUALLY I KEEP UPDATING IT BUT

1343
00:52:25,488 --> 00:52:27,657
IT SHOWS MORTALITY FROM

1344
00:52:27,657 --> 00:52:29,092
OVERDOSES FROM FENTANYL AMONG

1345
00:52:29,092 --> 00:52:29,525
TEENAGERS.

1346
00:52:29,525 --> 00:52:34,464
I SHOW IT IN BLUE FOR BOYS

1347
00:52:34,464 --> 00:52:36,232
TEENAGERS, IN PURPLE FOR GIRLS,

1348
00:52:36,232 --> 00:52:37,567
AND IN RED FOR THE AVERAGE.

1349
00:52:37,567 --> 00:52:40,937
AND I SHOW IT BECAUSE -- THIS IS

1350
00:52:40,937 --> 00:52:42,372
FOR TEENAGERS 15 TO 19, AND YOU

1351
00:52:42,372 --> 00:52:45,241
CAN SEE THAT WE SAW A BIG PEAK

1352
00:52:45,241 --> 00:52:47,310
DURING THE COVID PANDEMIC, THEN

1353
00:52:47,310 --> 00:52:48,644
IT WENT SLIGHTLY DOWN BUT THEN

1354
00:52:48,644 --> 00:52:50,546
IT BASICALLY HAS STABILIZED.

1355
00:52:50,546 --> 00:52:54,283
AND WE'RE SEEING -- AND IT

1356
00:52:54,283 --> 00:52:55,418
RAISES A BIG FLAG BECAUSE WE

1357
00:52:55,418 --> 00:52:57,253
HAVE NOT SEEN TEENAGERS DYING

1358
00:52:57,253 --> 00:53:01,190
FROM FENTANYL, AND DEATHS FROM

1359
00:53:01,190 --> 00:53:04,260
OVERDOSES IN TEENAGERS PRIMARILY

1360
00:53:04,260 --> 00:53:05,461
WERE DRIVEN BY ALCOHOL.

1361
00:53:05,461 --> 00:53:09,432
SO THIS WAS A DISRUPTION IN

1362
00:53:09,432 --> 00:53:10,733
PATTERNS THAT WE HAVE OBSERVED,

1363
00:53:10,733 --> 00:53:11,934
WHICH OF COURSE BEGS THE

1364
00:53:11,934 --> 00:53:14,036
QUESTION THAT NEEDS THIS

1365
00:53:14,036 --> 00:53:15,671
OBVIOUSLY REQUIRE ATTENTION AND

1366
00:53:15,671 --> 00:53:17,473
THE WAY THAT I HAVE PRESENTED IN

1367
00:53:17,473 --> 00:53:18,875
THE PAST AND I CONTINUED TO

1368
00:53:18,875 --> 00:53:19,976
PRESENT IN THE PAST.

1369
00:53:19,976 --> 00:53:21,944
IT ALSO HIGHLIGHTS HOW CRUCIAL

1370
00:53:21,944 --> 00:53:27,116
IT IS TO DO PREVENTION, BECAUSE

1371
00:53:27,116 --> 00:53:30,720
PREVENTION STARTING IN --

1372
00:53:30,720 --> 00:53:34,357
ADOLESCENCE, BECAUSE TEENAGERS

1373
00:53:34,357 --> 00:53:35,558
IN MONITORING THE FUTURE, WE

1374
00:53:35,558 --> 00:53:38,194
HAVE THE LOWEST, LOWEST RATES OF

1375
00:53:38,194 --> 00:53:40,430
PREVALENCE FOR HEROIN USE, AND

1376
00:53:40,430 --> 00:53:41,431
TEENAGERS DON'T SEEK OUT

1377
00:53:41,431 --> 00:53:41,731
FENTANYL.

1378
00:53:41,731 --> 00:53:44,901
SO HOW COME THEY END UP WITH

1379
00:53:44,901 --> 00:53:45,835
OVERDOSES WITH FENTANYL?

1380
00:53:45,835 --> 00:53:48,104
AND VERY LIKELY, BECAUSE THEY DO

1381
00:53:48,104 --> 00:53:51,174
SEEK OUT PRESCRIPTION DRUGS,

1382
00:53:51,174 --> 00:53:52,942
PSYCHOTHERAPEUTIC PRESCRIPTION

1383
00:53:52,942 --> 00:53:58,548
DRUGS.

1384
00:53:58,548 --> 00:54:00,616
AND ILLICIT PRESCRIPTION DRUGS

1385
00:54:00,616 --> 00:54:03,019
AND PSYCHOTHERAPEUTIC DRUGS,

1386
00:54:03,019 --> 00:54:05,888
ULTIMATELY AN AGEE SIX LIKE

1387
00:54:05,888 --> 00:54:09,091
OXYCONTIN AND VICODIN OR

1388
00:54:09,091 --> 00:54:12,261
HYPNOTICS LIE BENZODIAZEPINES

1389
00:54:12,261 --> 00:54:17,834
ARE ILLICITLY MANUFACTURED.

1390
00:54:17,834 --> 00:54:21,137
IF THE TEENAGER GETS THEIR HANDS

1391
00:54:21,137 --> 00:54:23,773
ON THESE ILLICITLY MANUFACTURED

1392
00:54:23,773 --> 00:54:26,309
PILLS THAT ARE LESS EXPENSIVE

1393
00:54:26,309 --> 00:54:28,277
THAN THOSE SOLD IN THE LEGAL

1394
00:54:28,277 --> 00:54:29,278
MARKET OR THEY ARE GIVEN TO THEM

1395
00:54:29,278 --> 00:54:30,713
BY A FRIEND OR WHICHEVER WAY

1396
00:54:30,713 --> 00:54:33,816
THEY GET IT, THEY ARE AT RISK OF

1397
00:54:33,816 --> 00:54:34,817
OVERDOSING WITH A SINGLE

1398
00:54:34,817 --> 00:54:35,084
EXPOSURE.

1399
00:54:35,084 --> 00:54:36,719
THIS IS, AGAIN, WHY PREVENTION

1400
00:54:36,719 --> 00:54:42,425
BECOMES SO VERY IMPORTANT.

1401
00:54:42,425 --> 00:54:43,693
SO LAST COUNCIL, I BROUGHT UP

1402
00:54:43,693 --> 00:54:46,829
THE POINT THAT BECAUSE OF THAT,

1403
00:54:46,829 --> 00:54:48,364
AS A NATIONAL ACADEMY OF

1404
00:54:48,364 --> 00:54:51,033
SCIENCES TO DO A BLUE POINT FOR

1405
00:54:51,033 --> 00:55:00,443
A NATIONAL -- I THIS IS BORN OF

1406
00:55:00,443 --> 00:55:01,744
THE FRUSTRATION THAT RECOGNIZING

1407
00:55:01,744 --> 00:55:04,080
AFTER DECADES OF RESEARCH ON

1408
00:55:04,080 --> 00:55:05,681
PREVENTION SCIENCE AND CLEARCUT

1409
00:55:05,681 --> 00:55:08,117
EVIDENCE OF PREVENTION

1410
00:55:08,117 --> 00:55:10,686
INTERVENTIONS, THESE ARE NOT

1411
00:55:10,686 --> 00:55:11,220
IMPLEMENTED.

1412
00:55:11,220 --> 00:55:12,989
SO WE WANT THE NATIONAL ACADEMY

1413
00:55:12,989 --> 00:55:18,227
TO LOOK INTO THIS AND TO ADDRESS

1414
00:55:18,227 --> 00:55:21,664
WHY IS ITNESS SAIR -- WHAT IS

1415
00:55:21,664 --> 00:55:22,765
NECESSARY FOR THESE TO BE

1416
00:55:22,765 --> 00:55:23,165
IMPLEMENTED.

1417
00:55:23,165 --> 00:55:23,833
WHAT ARE THE REQUIREMENTS IN

1418
00:55:23,833 --> 00:55:26,636
TERMS OF BEST PRACTICES IN TERMS

1419
00:55:26,636 --> 00:55:28,471
OF RESOURCES, IN TERMS OF

1420
00:55:28,471 --> 00:55:36,646
POLICIES THAT MAY BE NECESSARY.

1421
00:55:36,646 --> 00:55:38,414
AND ULTIMATELY WHAT ARE THE

1422
00:55:38,414 --> 00:55:39,282
RESEARCH GAPS THAT WOULD HELP

1423
00:55:39,282 --> 00:55:40,383
GUIDE US IN TERMS OF PRIORITY

1424
00:55:40,383 --> 00:55:41,617
AREAS THAT HE WITH NEED TO MOVE

1425
00:55:41,617 --> 00:55:42,184
FURTHER.

1426
00:55:42,184 --> 00:55:45,121
SO THIS IS WHERE WE ARE, AND

1427
00:55:45,121 --> 00:55:46,856
THEY HAD THE NATIONAL ACADEMIES

1428
00:55:46,856 --> 00:55:48,991
HELD THEIR FIRST IN-PERSON

1429
00:55:48,991 --> 00:55:50,793
MEETING, I THINK IT WAS TWO OR

1430
00:55:50,793 --> 00:55:53,262
THREE WEEKS AGO.

1431
00:55:53,262 --> 00:55:57,433
SO THEY ACTUALLY ARE WORKING AND

1432
00:55:57,433 --> 00:56:01,370
AS WE GET THEIR RECOMMENDATIONS,

1433
00:56:01,370 --> 00:56:02,305
OF COURSE, WE WILL BE UPDATING

1434
00:56:02,305 --> 00:56:03,339
YOU ALL.

1435
00:56:03,339 --> 00:56:06,242
BUT IT ALSO CERTAINLY FORCES --

1436
00:56:06,242 --> 00:56:07,443
IT CERTAINLY FORCED ME TO THINK,

1437
00:56:07,443 --> 00:56:12,648
I MEAN, YES, F THERE IS ALSO AT

1438
00:56:12,648 --> 00:56:13,849
THE SAME TIME YOU WANT TO

1439
00:56:13,849 --> 00:56:15,151
PREVENT TEENAGERS FROM TAKING

1440
00:56:15,151 --> 00:56:17,053
DRUGS, BUT ALSO AMONG THE

1441
00:56:17,053 --> 00:56:20,890
TEENAGERS THAT ARE AT HIGHER

1442
00:56:20,890 --> 00:56:24,393
RISK AT OVERDOSES, THOSE WHO

1443
00:56:24,393 --> 00:56:25,895
ALREADY HAVE A SUBSTANCE USE

1444
00:56:25,895 --> 00:56:27,730
DISORDER.

1445
00:56:27,730 --> 00:56:29,031
TEENAGERS, BASICALLY THEY DO GET

1446
00:56:29,031 --> 00:56:30,633
ADDICTED TO DRUGS, AND IF YOU

1447
00:56:30,633 --> 00:56:33,769
LOOK AT THE NUMBERS, THERE ARE

1448
00:56:33,769 --> 00:56:36,038
2.2 MILLION ADOLESCENTS AGED 12

1449
00:56:36,038 --> 00:56:38,207
TO 17 THAT MEET CRITERIA FOR A

1450
00:56:38,207 --> 00:56:40,543
SUBSTANCE USE DISORDER AS OF

1451
00:56:40,543 --> 00:56:42,912
2022 IN THE UNITED STATES.

1452
00:56:42,912 --> 00:56:44,480
2.2 MILLION.

1453
00:56:44,480 --> 00:56:46,983
SO IT'S NOT A NEGLIGIBLE NUMBER.

1454
00:56:46,983 --> 00:56:50,052
AND OF THOSE THAT HAVE A

1455
00:56:50,052 --> 00:56:52,655
SUBSTANCE USE DISORDER, ONLY .5%

1456
00:56:52,655 --> 00:56:55,358
RECEIVE TREATMENT.

1457
00:56:55,358 --> 00:56:56,792
ONLY .5%.

1458
00:56:56,792 --> 00:56:58,094
I ACTUALLY HAD TO READ AND THINK

1459
00:56:58,094 --> 00:57:01,464
ABOUT THAT NUMBER AND THINK HOW

1460
00:57:01,464 --> 00:57:03,165
CAN IT BE SO VERY LOW?

1461
00:57:03,165 --> 00:57:06,469
WHICH CORRESPONDS TO ONLY 8,000

1462
00:57:06,469 --> 00:57:10,606
TEENAGERS RECEIVE TREATMENT.

1463
00:57:10,606 --> 00:57:13,509
SO THIS IS AN URGENT, URGENT GAP

1464
00:57:13,509 --> 00:57:16,212
THAT NEEDS TO BE ADDRESSED.

1465
00:57:16,212 --> 00:57:19,782
AND ALSO IT FORCES, THEREFORE,

1466
00:57:19,782 --> 00:57:20,716
INTO UNDERSTANDING TO WHERE ARE

1467
00:57:20,716 --> 00:57:23,285
WE WITH THE TREATMENT FOR

1468
00:57:23,285 --> 00:57:26,455
ADOLESCENTS THAT HAVE A

1469
00:57:26,455 --> 00:57:28,024
SUBSTANCE USE DISORDER, WHERE IS

1470
00:57:28,024 --> 00:57:28,391
THE EVIDENCE.

1471
00:57:28,391 --> 00:57:30,226
AND THE EVIDENCE IS THERE THAT

1472
00:57:30,226 --> 00:57:31,594
PSYCHOSOCIAL TREATMENTS ACTUALLY

1473
00:57:31,594 --> 00:57:33,062
ARE EFFECTIVE IN TREATING

1474
00:57:33,062 --> 00:57:35,431
SUBSTANCE USE DISORDERS IN

1475
00:57:35,431 --> 00:57:37,600
TEENAGERS, WHETHER IT IS

1476
00:57:37,600 --> 00:57:38,934
MOTIVATIONAL, COGNITIVE

1477
00:57:38,934 --> 00:57:40,836
BEHAVIORAL, FAMILY ORIENTED

1478
00:57:40,836 --> 00:57:44,440
THERAPIES, AND B CONTINGENCY

1479
00:57:44,440 --> 00:57:45,307
MANAGEMENT, THEY ALL HAVE SHOWN

1480
00:57:45,307 --> 00:57:46,776
THAT THEY ARE EFFECTIVE FOR

1481
00:57:46,776 --> 00:57:48,411
VARIOUS SUBSTANCE USE DISORDER.

1482
00:57:48,411 --> 00:57:50,146
BUT WE HAVE TO RECOGNIZE ALSO

1483
00:57:50,146 --> 00:57:52,381
THAT THE EFFECT SIZES ARE SMALL

1484
00:57:52,381 --> 00:57:53,149
TO MODEST.

1485
00:57:53,149 --> 00:57:56,552
SO THERE IS AN URGENT NEED TO

1486
00:57:56,552 --> 00:57:58,621
IMPROVE ACTUALLY ALTERNATIVE

1487
00:57:58,621 --> 00:58:01,390
TREATMENTS THAT CAN GET LARGER

1488
00:58:01,390 --> 00:58:03,059
EFFECTS.

1489
00:58:03,059 --> 00:58:05,361
FROM THE WORLD OF MEDICATIONS

1490
00:58:05,361 --> 00:58:09,498
WHERE WE KNOW ALREADY NOW THAT

1491
00:58:09,498 --> 00:58:11,200
INDICATIONS FOR OPIATE USE

1492
00:58:11,200 --> 00:58:12,301
DISORDER IS THE MOST EFFECTIVE

1493
00:58:12,301 --> 00:58:13,936
INTERVENTION THAT WE HAVE, WE

1494
00:58:13,936 --> 00:58:18,107
KNOW THAT THERE IS THE

1495
00:58:18,107 --> 00:58:20,276
FDA-APPROVED BUPRENORPHINE FOR

1496
00:58:20,276 --> 00:58:21,310
OPIOID USE DISORDER IN

1497
00:58:21,310 --> 00:58:23,713
INDIVIDUALS THAT ARE 16 YEARS OF

1498
00:58:23,713 --> 00:58:28,751
AGE OR OLDER, BUT WE DON'T HAVE,

1499
00:58:28,751 --> 00:58:30,186
REALLY, EVIDENCE THAT HAS BEEN

1500
00:58:30,186 --> 00:58:33,622
DONE TO EVALUATE THE UTILITY IN

1501
00:58:33,622 --> 00:58:34,623
YOUNGER TEENAGERS.

1502
00:58:34,623 --> 00:58:37,793
NOR IS THERE DATA, CLINICAL

1503
00:58:37,793 --> 00:58:41,430
TRIAL DATA FOR METHADONE, EVEN

1504
00:58:41,430 --> 00:58:43,499
THOUGH IT IS ALLOWED TO

1505
00:58:43,499 --> 00:58:44,366
ACTUALLY -- AS I WAS COMMENTING

1506
00:58:44,366 --> 00:58:46,502
BEFORE, A TEENAGER CAN BE

1507
00:58:46,502 --> 00:58:49,338
PRESCRIBED METHADONE THROUGH THE

1508
00:58:49,338 --> 00:58:50,106
OPIATE TREATMENT PROGRAM

1509
00:58:50,106 --> 00:58:52,141
PROVIDED THAT THEY HAVE FAILED

1510
00:58:52,141 --> 00:58:53,776
THROUGH OTHER INTERVENTIONS.

1511
00:58:53,776 --> 00:58:55,411
BUT IT IS VERY FEW OF THEM GET

1512
00:58:55,411 --> 00:58:56,712
ACCESS TO METHADONE AND WE

1513
00:58:56,712 --> 00:59:00,149
REALLY HA HAVE NOT DONE THE

1514
00:59:00,149 --> 00:59:01,150
CLINICAL TRIALS THAT COULD

1515
00:59:01,150 --> 00:59:02,551
OPTIMALLY HELP US GUIDE WHAT ARE

1516
00:59:02,551 --> 00:59:04,920
THE DOSES, HOW TO INTERVENE, AND

1517
00:59:04,920 --> 00:59:07,656
WHO SHOULD BE -- UNDER WHAT

1518
00:59:07,656 --> 00:59:08,524
CONDITIONS IT IS ACTUALLY

1519
00:59:08,524 --> 00:59:08,858
JUSTIFIED.

1520
00:59:08,858 --> 00:59:13,963
AND SIMILARLY, NALTREXONE IS

1521
00:59:13,963 --> 00:59:16,031
PARTICULARLY INTERESTING AND

1522
00:59:16,031 --> 00:59:16,799
MERITS FURTHER INVESTIGATION

1523
00:59:16,799 --> 00:59:19,201
BECAUSE IF YOU HAVE TEENAGERS

1524
00:59:19,201 --> 00:59:21,103
THAT ARE IN THE EARLY STAGES OF

1525
00:59:21,103 --> 00:59:23,739
A SUBSTANCE -- AN OPIOID USE

1526
00:59:23,739 --> 00:59:25,474
DISORDER WHERE YOU DON'T WANT TO

1527
00:59:25,474 --> 00:59:29,578
ACTUALLY PLACE THEM ON AN OPIOID

1528
00:59:29,578 --> 00:59:32,414
AGONIST, EVEN IF IT'S A PARTIAL

1529
00:59:32,414 --> 00:59:34,183
AGONIST, NALTREXONE OFFERS

1530
00:59:34,183 --> 00:59:37,520
PROTECTION FOR THEM FROM

1531
00:59:37,520 --> 00:59:40,356
OVERDOSE, SO -- BUT WITHOUT

1532
00:59:40,356 --> 00:59:43,292
RESEARCH, WE REALLY DO NOT KNOW

1533
00:59:43,292 --> 00:59:45,461
HOW BENEFICIAL IT COULD BE, BUT

1534
00:59:45,461 --> 00:59:47,296
IT ABSOLUTELY SHOULD BE A

1535
00:59:47,296 --> 00:59:48,864
PRIORITY IN TERMS OF FUTURE

1536
00:59:48,864 --> 00:59:54,970
RESEARCH.

1537
00:59:54,970 --> 00:59:56,872
I WANT TO END MY PRESENTATION

1538
00:59:56,872 --> 00:59:57,907
JUST BY TWO ANNOUNCEMENTS.

1539
00:59:57,907 --> 01:00:00,709
ONE OF THEM IS THE POPULATION

1540
01:00:00,709 --> 01:00:06,315
ASSESSMENT OF TOBACCO AND

1541
01:00:06,315 --> 01:00:08,951
HEALTH, THE PATH STUDY

1542
01:00:08,951 --> 01:00:10,152
CONTINUATION, NATIONALLY

1543
01:00:10,152 --> 01:00:10,719
REPRESENTATIVE LONGITUDINAL

1544
01:00:10,719 --> 01:00:12,955
COHORT STUDY OF TOBACCO USE, ITS

1545
01:00:12,955 --> 01:00:16,025
DETERMINANTS AND IMPACT ON U.S.

1546
01:00:16,025 --> 01:00:17,993
POPULATIONS AGE 12 AND OLDER, IT

1547
01:00:17,993 --> 01:00:19,762
STARTED COLLECTING DATA SINCE

1548
01:00:19,762 --> 01:00:20,896
2013 FOR SEVEN COMPLETED FULL

1549
01:00:20,896 --> 01:00:22,198
WAVES AND THREE SPECIAL DATA

1550
01:00:22,198 --> 01:00:22,765
COLLECTIONS.

1551
01:00:22,765 --> 01:00:24,466
SO THAT'S MORE THAN 45,000

1552
01:00:24,466 --> 01:00:25,568
BASELINE ASSESSMENTS.

1553
01:00:25,568 --> 01:00:28,838
AND IT HAS LED TO 800

1554
01:00:28,838 --> 01:00:29,805
PUBLICATIONS AND THE DATA IS

1555
01:00:29,805 --> 01:00:30,840
AVAILABLE FOR RESEARCHERS

1556
01:00:30,840 --> 01:00:31,841
THROUGH THIS LINK THAT I'M

1557
01:00:31,841 --> 01:00:39,048
SHOWING YOU HERE.

1558
01:00:39,048 --> 01:00:43,919
THE PATH STUDY HAS BEEN

1559
01:00:43,919 --> 01:00:46,188
SUPPORTED THROUGH TWO CONTRACTS,

1560
01:00:46,188 --> 01:00:50,059
FIVE AND EIGHT YEARS, AND ON

1561
01:00:50,059 --> 01:00:51,727
FEBRUARY 1ST, A CONTRACT WAS

1562
01:00:51,727 --> 01:00:54,597
AWARDED TO WESTAT TO SUPPORT

1563
01:00:54,597 --> 01:00:56,765
4 ADDITIONAL WAVES OF DATA

1564
01:00:56,765 --> 01:00:58,901
COLLECTION OVER EIGHT YEARS,

1565
01:00:58,901 --> 01:01:00,536
FROM 2024 TO 2032.

1566
01:01:00,536 --> 01:01:02,071
THE PATH IS ADMINISTERED BY NIDA

1567
01:01:02,071 --> 01:01:03,973
AND IS FUNDED PRIMARILY BY THE

1568
01:01:03,973 --> 01:01:05,641
FDA CENTER FOR TOBACCO PRODUCTS,

1569
01:01:05,641 --> 01:01:08,477
AND THIS YEAR THE FUNDING HAS

1570
01:01:08,477 --> 01:01:14,917
BEEN BASICALLY NOW ALSO DONE BY

1571
01:01:14,917 --> 01:01:19,255
ADDITIONAL FUNDS FROM NIDA, NCI,

1572
01:01:19,255 --> 01:01:25,327
NHLBI, NIMHD, NIAAA, NIDDK,

1573
01:01:25,327 --> 01:01:28,230
OBSSR, NIEHS, OTP AND NLM.

1574
01:01:28,230 --> 01:01:30,299
AND MY FINAL SLIDE IS ONE THAT I

1575
01:01:30,299 --> 01:01:31,634
LIKE TO BRAG ACTUALLY BECAUSE I

1576
01:01:31,634 --> 01:01:33,435
THINK IT'S VERY, VERY EXCITING,

1577
01:01:33,435 --> 01:01:36,272
IT HI HIGHLIGHTS THE FIRST AWARD

1578
01:01:36,272 --> 01:01:38,574
FOR ONE OF OUR TRANSLATION

1579
01:01:38,574 --> 01:01:41,710
PROGRAMS WITH OTP THAT BASICALLY

1580
01:01:41,710 --> 01:01:44,747
GOT THE NUMBER ONE GOLD MEDAL

1581
01:01:44,747 --> 01:01:47,182
FOR BEING THE INSTITUTE AT THE

1582
01:01:47,182 --> 01:01:50,619
NIH THAT HAS SPONSORED THE MOST

1583
01:01:50,619 --> 01:01:51,287
CHALLENGES.

1584
01:01:51,287 --> 01:01:53,622
AND I ALSO WANT TO REITERATE, IT

1585
01:01:53,622 --> 01:01:55,791
WAS ALSO, I THINK, THE FIRST

1586
01:01:55,791 --> 01:01:57,493
INSTITUTE THAT INITIATED THE USE

1587
01:01:57,493 --> 01:01:59,094
OF CHALLENGE TO ACTUALLY ADVANCE

1588
01:01:59,094 --> 01:02:00,095
THE SCIENCE.

1589
01:02:00,095 --> 01:02:01,463
AND WITH THAT, I WANT TO THANK

1590
01:02:01,463 --> 01:02:05,067
YOU FOR YOUR ATTENTION, ANDLY

1591
01:02:05,067 --> 01:02:06,602
STOP SHARING SO IF THERE ARE

1592
01:02:06,602 --> 01:02:09,405
QUESTIONS, I CAN ADDRESS THEM.

1593
01:02:09,405 --> 01:02:19,715
THANKS VERY MUCH.

1594
01:02:20,649 --> 01:02:23,185
>> NORA, I CAN -- I DON'T

1595
01:02:23,185 --> 01:02:23,419
KNOW --

1596
01:02:23,419 --> 01:02:26,088
>> GO AHEAD, RAJITA.

1597
01:02:26,088 --> 01:02:27,957
>> THANK YOU, NORA, FOR
THAT

1598
01:02:27,957 --> 01:02:31,327
VERY COMPREHENSIVE SUMMARY OF

1599
01:02:31,327 --> 01:02:36,532
THE STATE OF THE SCIENCE AND THE

1600
01:02:36,532 --> 01:02:39,802
DATA WITH ADOLESCENTS, THEIR

1601
01:02:39,802 --> 01:02:41,870
OVERDOSES AND INITIATION BUT

1602
01:02:41,870 --> 01:02:45,207
ALSO DAILY USE GOING UP IS

1603
01:02:45,207 --> 01:02:47,943
ALARMING, SO WE SHARE YOUR

1604
01:02:47,943 --> 01:02:50,012
CONCERN THERE.

1605
01:02:50,012 --> 01:02:52,648
THE QUESTION I WANTED TO RAISE

1606
01:02:52,648 --> 01:02:53,882
JUST SORT OF TAKING A STEP BACK

1607
01:02:53,882 --> 01:02:58,153
AND DOING MORE OF A LONG VIEW,

1608
01:02:58,153 --> 01:02:59,655
CANNABIS IS VERY MUCH PRESENT IN

1609
01:02:59,655 --> 01:03:01,790
A LOT OF THIS IN TERMS OF

1610
01:03:01,790 --> 01:03:04,560
THINKING OF PREVENTION OF

1611
01:03:04,560 --> 01:03:06,962
ADOLESCENTS BUT ALSO ADULTS, AND

1612
01:03:06,962 --> 01:03:08,831
WHERE THINGS START IN TERMS OF

1613
01:03:08,831 --> 01:03:11,633
SUBSTANCE USE AND MISUSE.

1614
01:03:11,633 --> 01:03:13,168
ALCOHOL AND CANNABIS AND

1615
01:03:13,168 --> 01:03:15,104
NICOTINE BEING UP THERE AS

1616
01:03:15,104 --> 01:03:15,771
PATHWAY DRUG.

1617
01:03:15,771 --> 01:03:17,306
ONE THING THAT HAS COME UP IN

1618
01:03:17,306 --> 01:03:19,308
OUR REALM AND PEOPLE -- AND FROM

1619
01:03:19,308 --> 01:03:23,078
THE PUBLIC HAVE ASKED IS, IS

1620
01:03:23,078 --> 01:03:23,712
CANNABIS HARMFUL?

1621
01:03:23,712 --> 01:03:25,180
THIS IS ALWAYS COMING UP, WE ALL

1622
01:03:25,180 --> 01:03:25,714
HEAR THIS.

1623
01:03:25,714 --> 01:03:31,120
AND SO ONE QUESTION I HAD FOR US

1624
01:03:31,120 --> 01:03:31,754
SCIENTIFICALLY, IS THERE A PLACE

1625
01:03:31,754 --> 01:03:33,022
FOR US TO START THINKING ABOUT

1626
01:03:33,022 --> 01:03:34,089
THRESHOLDS OF HARM?

1627
01:03:34,089 --> 01:03:37,726
JUST AS WE DO WITH ALCOHOL, WE

1628
01:03:37,726 --> 01:03:39,261
HAVE HAZARDOUS DRINKING

1629
01:03:39,261 --> 01:03:42,264
THRESHOLDS AND I KNOW HOW WE'RE

1630
01:03:42,264 --> 01:03:43,999
INVOLVED IN THE PROCESS OF HOW

1631
01:03:43,999 --> 01:03:45,434
THAT CAME ABOUT, WHERE WE WERE

1632
01:03:45,434 --> 01:03:48,337
ABLE TO IDENTIFY BINGE DRINKING

1633
01:03:48,337 --> 01:03:49,738
THRESHOLDS AND HAZARDOUS LEVELS,

1634
01:03:49,738 --> 01:03:51,507
AND I JUST WONDER, LOOKING INTO

1635
01:03:51,507 --> 01:03:53,108
THE FUTURE AND EVEN THE CURRENT

1636
01:03:53,108 --> 01:03:55,711
TRENDS OF WHERE CANNABIS IS

1637
01:03:55,711 --> 01:03:59,014
GOING, WITH LEGALIZATION,

1638
01:03:59,014 --> 01:04:00,983
WHETHER IT BEHOOVES US TO

1639
01:04:00,983 --> 01:04:02,885
CONSIDER TO THINK ABOUT

1640
01:04:02,885 --> 01:04:06,488
INITIATING SOME KIND OF PROCESS

1641
01:04:06,488 --> 01:04:08,924
BY WHICH WE CAN DETERMINE

1642
01:04:08,924 --> 01:04:11,427
THRESHOLDS OF HARM, SAFE LEVELS

1643
01:04:11,427 --> 01:04:11,894
OF CANNABIS.

1644
01:04:11,894 --> 01:04:13,829
I KNOW IT'S A THORNY ISSUE, BUT

1645
01:04:13,829 --> 01:04:16,331
I WANTED TO RAISE IT AND WHETHER

1646
01:04:16,331 --> 01:04:19,468
THERE COULD EVEN BE A WORK GROUP

1647
01:04:19,468 --> 01:04:21,870
OR GRANTS, I'M JUST SORT OF

1648
01:04:21,870 --> 01:04:22,838
THINKING, BRAINSTORMING HERE, TO

1649
01:04:22,838 --> 01:04:25,574
THINK ABOUT THAT, BECAUSE THIS

1650
01:04:25,574 --> 01:04:27,376
IS NOT GOING TO GO AWAY AND IT'S

1651
01:04:27,376 --> 01:04:28,510
ONLY GROWING IN TERMS OF NUMBER

1652
01:04:28,510 --> 01:04:30,179
OF STATES LEGALIZING IT AND

1653
01:04:30,179 --> 01:04:33,782
INCREASING NUMBERS OF CHILDREN,

1654
01:04:33,782 --> 01:04:34,750
ADOLESCENTS AND YOUNG ADULTS

1655
01:04:34,750 --> 01:04:35,984
USING IT AND GOING DOWN THE

1656
01:04:35,984 --> 01:04:38,420
PATHWAY OF SUBSTANCE USE

1657
01:04:38,420 --> 01:04:39,621
DISORDERS RISK.

1658
01:04:39,621 --> 01:04:41,056
>> RAJITA, THANKS FOR
BRINGING

1659
01:04:41,056 --> 01:04:42,257
THAT UP.

1660
01:04:42,257 --> 01:04:45,794
ABSOLUTELY, YO INCREDIBLE

1661
01:04:45,794 --> 01:04:46,095
SUGGESTION.

1662
01:04:46,095 --> 01:04:50,833
I THINK ONE OF T REASONS WHY WE

1663
01:04:50,833 --> 01:04:55,838
PROPOSED A STANDARD UNIT WAS IN

1664
01:04:55,838 --> 01:04:56,371
UNDERSTANDING IS THERE A

1665
01:04:56,371 --> 01:04:57,573
THRESHOLD OF RISK.

1666
01:04:57,573 --> 01:04:59,041
OBVIOUSLY THAT THRESHOLD OF RISK

1667
01:04:59,041 --> 01:05:00,375
IS GOING TO VERY MUCH DEPEND IN

1668
01:05:00,375 --> 01:05:01,810
PART ON YOUR DEMOGRAPHICS, SO WE

1669
01:05:01,810 --> 01:05:02,878
KNOW THAT.

1670
01:05:02,878 --> 01:05:05,280
AND ALSO YOUR UNIQUE

1671
01:05:05,280 --> 01:05:06,682
CHARACTERISTICS OF DO YOU HAVE A

1672
01:05:06,682 --> 01:05:08,550
HISTORY OF PSYCHIATRIC DISEASES,

1673
01:05:08,550 --> 01:05:10,619
LIKE PSYCHOSIS, YOU ARE AT MUCH

1674
01:05:10,619 --> 01:05:14,423
GREATER RISK.

1675
01:05:14,423 --> 01:05:16,558
BUT WITH RESPECT TO THE

1676
01:05:16,558 --> 01:05:17,893
THRESHOLD, I THINK WE SHOULD

1677
01:05:17,893 --> 01:05:19,061
TACKLE IT ABSOLUTELY.

1678
01:05:19,061 --> 01:05:20,329
IN ADOLESCENCE, THAT'S WHAT

1679
01:05:20,329 --> 01:05:23,065
ACTUALLY -- WHEN I PROPOSED TO

1680
01:05:23,065 --> 01:05:25,601
GEORGE I SAID LET'S DO THIS FOR

1681
01:05:25,601 --> 01:05:27,069
THE ABCD, BECAUSE THAT WOULD

1682
01:05:27,069 --> 01:05:28,937
ALLOW US TO UNDERSTAND AND NOW

1683
01:05:28,937 --> 01:05:33,008
THE TEENAGERS, WHICH ARE 16

1684
01:05:33,008 --> 01:05:34,576
YEARS OF AGE, ARE STARTING TO

1685
01:05:34,576 --> 01:05:36,545
SMOKE MARIJUANA, BUT WE HAVE

1686
01:05:36,545 --> 01:05:37,746
THEIR BRAIN SCAN AND THEIR

1687
01:05:37,746 --> 01:05:38,714
BEHAVIOR BEFORE THEY ACTUALLY

1688
01:05:38,714 --> 01:05:41,750
STARTED TO USE IT.

1689
01:05:41,750 --> 01:05:43,919
AND THE SIZE -- WE POWERED THE

1690
01:05:43,919 --> 01:05:45,587
STUDY OF THE ABCD TO BE SURE TO

1691
01:05:45,587 --> 01:05:47,689
BE ABLE TO ADDRESS THE QUESTION

1692
01:05:47,689 --> 01:05:52,094
OF CANNABIS EFFECTS IN THE BRAIN

1693
01:05:52,094 --> 01:05:53,162
DEVELOPMENT OF TEENAGERS, IN

1694
01:05:53,162 --> 01:05:54,763
ORDER TO GET THAT SENSE OF

1695
01:05:54,763 --> 01:05:55,197
THRESHOLD.

1696
01:05:55,197 --> 01:05:57,065
WE HAVE HAD SOME DIFFICULTY

1697
01:05:57,065 --> 01:05:59,368
ACTUALLY OF IMPLEMENTING THE

1698
01:05:59,368 --> 01:06:01,537
STANDARD UNIT DOSE, SO WE

1699
01:06:01,537 --> 01:06:03,138
BASICALLY SAID IF YOU ARE GOING

1700
01:06:03,138 --> 01:06:05,340
TO GET MONEY FROM NIDA TO STUDY

1701
01:06:05,340 --> 01:06:07,009
THE EFFECTS OF CANNABIS, YOU

1702
01:06:07,009 --> 01:06:08,777
HAVE TO MAKE AN ATTEMPT TO

1703
01:06:08,777 --> 01:06:10,245
ACTUALLY TRANSLATE IT INTO

1704
01:06:10,245 --> 01:06:10,646
STANDARD DOSES.

1705
01:06:10,646 --> 01:06:14,082
SO FOR THE ABCD, WE WILL KEEP ON

1706
01:06:14,082 --> 01:06:18,353
PUSHING TO TRY TO GET THE PIs

1707
01:06:18,353 --> 01:06:20,455
TO PUSH THEIR PEOPLE TO GET

1708
01:06:20,455 --> 01:06:22,491
STANDARD DOSES BUT AS OF NOW, I

1709
01:06:22,491 --> 01:06:26,094
HAVE NOT SEEN THE UPTICK THAT I

1710
01:06:26,094 --> 01:06:27,729
WOULD LIKE TO DO IT.

1711
01:06:27,729 --> 01:06:28,664
MEANWHILE -- THAT'S ADOLESCENTS.

1712
01:06:28,664 --> 01:06:30,299
BUT YOUR QUESTION IS THRESHOLD,

1713
01:06:30,299 --> 01:06:31,733
AND THRESHOLD IS GOING TO BE

1714
01:06:31,733 --> 01:06:34,069
AFFECTED BY OTHER FACTORS.

1715
01:06:34,069 --> 01:06:40,108
AND WE HAVE VERY LITTLE DATA ON

1716
01:06:40,108 --> 01:06:41,176
THAT, AND I THINK WHEN WE'RE

1717
01:06:41,176 --> 01:06:42,277
SPEAKING ABOUT HAVING A

1718
01:06:42,277 --> 01:06:44,980
GUIDELINE, WE NEED TO BUILD THAT

1719
01:06:44,980 --> 01:06:45,447
DATA.

1720
01:06:45,447 --> 01:06:46,515
ONE OF THE ASPECTS THAT WE'VE

1721
01:06:46,515 --> 01:06:50,485
DONE IS CREATED A REGISTRY FOR,

1722
01:06:50,485 --> 01:06:54,890
AGAIN, PEOPLE THAT ARE USING

1723
01:06:54,890 --> 01:06:55,457
MARIJUANA, CANNABIS, WHETHER

1724
01:06:55,457 --> 01:06:57,326
IT'S MEDICAL OR OTHER PURPOSES,

1725
01:06:57,326 --> 01:06:58,860
TO TRY TO GET A BETTER

1726
01:06:58,860 --> 01:07:00,095
UNDERSTANDING OF WHETHER IT HAS

1727
01:07:00,095 --> 01:07:04,566
NEGATIVE CONSEQUENCES.

1728
01:07:04,566 --> 01:07:06,268
WE'RE ALSO IN DISCUSSION WITH

1729
01:07:06,268 --> 01:07:08,136
JOSH DENNY, DIRECTOR OF THE

1730
01:07:08,136 --> 01:07:10,539
ALL-OF-US PROGRAM THAT BASICALLY

1731
01:07:10,539 --> 01:07:12,174
AIMS TO FOLLOW A MILLION PEOPLE

1732
01:07:12,174 --> 01:07:13,875
IN THE UNITED STATES WITH THEIR

1733
01:07:13,875 --> 01:07:15,410
ELECTRONIC HEALTH RECORDS TO

1734
01:07:15,410 --> 01:07:19,248
ENSURE THAT ACTUALLY THERE WILL

1735
01:07:19,248 --> 01:07:21,116
BE INFORMATION RELATED TO THE

1736
01:07:21,116 --> 01:07:22,818
CONSUMPTION OF DRUGS INCLUDING

1737
01:07:22,818 --> 01:07:24,019
MEDICAL CANNABIS AND HE HAS BEEN

1738
01:07:24,019 --> 01:07:28,056
OPEN TO DISCUSS IT, BECAUSE THAT

1739
01:07:28,056 --> 01:07:29,124
WILL BE AN INCREDIBLE

1740
01:07:29,124 --> 01:07:31,960
OPPORTUNITY TO START TO PIECE

1741
01:07:31,960 --> 01:07:34,263
OUT WHAT PATTERNS ARE LINKED

1742
01:07:34,263 --> 01:07:36,565
WITH HARMFUL EFFECTS.

1743
01:07:36,565 --> 01:07:38,200
OTHERWISE I'M AFRAID THAT WE'RE

1744
01:07:38,200 --> 01:07:40,235
REALLY IN THE DARKNESS, RAJITA,

1745
01:07:40,235 --> 01:07:44,172
BUT I AGREE, AND I THINK THAT IN

1746
01:07:44,172 --> 01:07:45,140
FOLLOWING YOUR SUGGESTION

1747
01:07:45,140 --> 01:07:48,076
PERHAPS IT MAY BE WORTHWHILE TO

1748
01:07:48,076 --> 01:07:51,580
BRING TOGETHER PEOPLE TO THINK

1749
01:07:51,580 --> 01:07:53,215
ABOUT WHAT STEPS COULD

1750
01:07:53,215 --> 01:07:54,182
ACCELERATE US TO BE IN A

1751
01:07:54,182 --> 01:07:55,784
POSITION WHERE WE COULD CREATE

1752
01:07:55,784 --> 01:07:59,855
THOSE GUIDELINES.

1753
01:07:59,855 --> 01:08:01,290
SO I WISH THEY'D SAY LET'S

1754
01:08:01,290 --> 01:08:02,291
CREATE THOSE GUIDELINES, WE

1755
01:08:02,291 --> 01:08:03,225
DON'T HAVE THE KNOWLEDGE YET.

1756
01:08:03,225 --> 01:08:03,558
>> RIGHT.

1757
01:08:03,558 --> 01:08:07,062
THANK YOU.

1758
01:08:07,062 --> 01:08:08,030
>> ARPANA.

1759
01:08:08,030 --> 01:08:08,497
>> THANK YOU.

1760
01:08:08,497 --> 01:08:10,699
I ACTUALLY GOT SO EXCITED BY

1761
01:08:10,699 --> 01:08:11,700
RAJITA'S QUESTION, I ALMOST

1762
01:08:11,700 --> 01:08:15,404
FORGOT MY QUESTION.

1763
01:08:15,404 --> 01:08:16,071
I SECOND HER COMMENT.

1764
01:08:16,071 --> 01:08:17,673
I THINK THIS WOULD BE INCREDIBLE

1765
01:08:17,673 --> 01:08:19,541
TO DO, ESPECIALLY WITH AS YOU

1766
01:08:19,541 --> 01:08:20,642
MENTIONED, NORA, CHANGING

1767
01:08:20,642 --> 01:08:22,077
POTENCY LEVELS, SO WHAT OUR

1768
01:08:22,077 --> 01:08:23,378
YOUTH ARE GETTING TODAY ARE

1769
01:08:23,378 --> 01:08:25,113
PROBABLY NOT WHAT YOUTH RECEIVED

1770
01:08:25,113 --> 01:08:27,416
EVEN, YOU KNOW, A DECADE AGO.

1771
01:08:27,416 --> 01:08:29,785
BUT I HAVE A COMMENT AND A WISH,

1772
01:08:29,785 --> 01:08:31,186
IF YOU WILL.

1773
01:08:31,186 --> 01:08:35,691
MY COMMENT IS REALLY TO

1774
01:08:35,691 --> 01:08:38,060
CONGRATULATE YOU AND NIDA ON

1775
01:08:38,060 --> 01:08:39,695
ABCD AND HBCD.

1776
01:08:39,695 --> 01:08:41,763
TO MY KNOWLEDGE, AS SOMEBODY WHO

1777
01:08:41,763 --> 01:08:43,098
USES A LOT OF LARGE DATASETS,

1778
01:08:43,098 --> 01:08:46,535
THESE ARE UNPREPRECEDENTED

1779
01:08:46,535 --> 01:08:47,636
PROJECTS.

1780
01:08:47,636 --> 01:08:48,904
THEY'RE LONGITUDAL STUDYING

1781
01:08:48,904 --> 01:08:49,237
CHILDREN.

1782
01:08:49,237 --> 01:08:51,206
THEY HAVE BIOLOGICAL DATA AS YOU

1783
01:08:51,206 --> 01:08:53,075
MENTIONED, THEY HAVE RICH SOCIAL

1784
01:08:53,075 --> 01:08:54,543
DETERMINANTS OF HEALTH DATA, AND

1785
01:08:54,543 --> 01:08:56,078
THERE ARE NO SUCH DATASETS.

1786
01:08:56,078 --> 01:08:58,480
SO I REALLY THINK THIS HAS BEEN

1787
01:08:58,480 --> 01:09:02,818
A GAME CHANGER FOR THE FIELD, IN

1788
01:09:02,818 --> 01:09:04,353
PARTICULAR, FOR YOUNG PEOPLE,

1789
01:09:04,353 --> 01:09:06,755
FOR YOUNG INVESTIGATORS, FOR

1790
01:09:06,755 --> 01:09:09,024
TRAINEES, PRE-DOCS, POSTDOCS WHO

1791
01:09:09,024 --> 01:09:10,425
ARE ABLE TO DOWNLOAD THESE DATA

1792
01:09:10,425 --> 01:09:13,295
WITH THE VERY HIGH STANDARD --

1793
01:09:13,295 --> 01:09:14,229
FOR DATA SHARING.

1794
01:09:14,229 --> 01:09:15,564
AND TO BE ABLE TO TEST NEW

1795
01:09:15,564 --> 01:09:17,966
METHODS, I MEAN, THEY ARE AT THE

1796
01:09:17,966 --> 01:09:18,900
FOREFRONT OF METHODS

1797
01:09:18,900 --> 01:09:19,368
DEVELOPMENT.

1798
01:09:19,368 --> 01:09:20,535
THEY'RE ABLE TO PULL THESE DATA

1799
01:09:20,535 --> 01:09:22,504
AND DO THINGS WITH IT THAT I

1800
01:09:22,504 --> 01:09:23,605
CAN'T CONCEIVE OF THESE THINGS,

1801
01:09:23,605 --> 01:09:25,006
BUT IT'S JUST INCREDIBLE, HOW

1802
01:09:25,006 --> 01:09:26,742
MUCH INNOVATION HAS HAPPENED.

1803
01:09:26,742 --> 01:09:28,276
THE OTHER THING THAT I WANT TO

1804
01:09:28,276 --> 01:09:30,212
COMMENT ON WITH ABCD IN

1805
01:09:30,212 --> 01:09:33,048
PARTICULAR AND HBCD FORTHCOMING

1806
01:09:33,048 --> 01:09:34,883
IS THE COMMUNITY-FACING

1807
01:09:34,883 --> 01:09:35,250
COMPONENT.

1808
01:09:35,250 --> 01:09:37,386
WHEN RESEARCH PROJECTS ARE

1809
01:09:37,386 --> 01:09:39,354
COMPLETED, THERE IS AN

1810
01:09:39,354 --> 01:09:40,555
INFOGRAPHIC OR SOMETHING THAT'S

1811
01:09:40,555 --> 01:09:43,225
A VISUAL THAT IS

1812
01:09:43,225 --> 01:09:44,226
COMMUNITY-FACING, AND I'VE USED

1813
01:09:44,226 --> 01:09:45,761
IT AS A PARENT, I'VE USED IT AS

1814
01:09:45,761 --> 01:09:47,629
SOMEBODY WHO SERVES ON SCHOOL

1815
01:09:47,629 --> 01:09:48,897
BOARDS, BECAUSE THESE ARE

1816
01:09:48,897 --> 01:09:50,532
INCREDIBLY USEFUL TO TALK ABOUT

1817
01:09:50,532 --> 01:09:54,369
HOW SOCIAL MEDIA OR VIEWING TIME

1818
01:09:54,369 --> 01:09:56,405
OR SLEEP IS INFLUENCED IN YOUTH,

1819
01:09:56,405 --> 01:09:58,039
AND TO HAVE SOMETHING EMPIRICAL

1820
01:09:58,039 --> 01:10:00,041
THAT CAN BE USED OUTSIDE OF THE

1821
01:10:00,041 --> 01:10:01,109
RESEARCH CONTEXT, I THINK HAS

1822
01:10:01,109 --> 01:10:02,944
BEEN REMARKABLE.

1823
01:10:02,944 --> 01:10:06,848
SO MY WISH IS THAT ABCD AND HBCD

1824
01:10:06,848 --> 01:10:08,717
WILL CONTINUE TO THRIVE, AND

1825
01:10:08,717 --> 01:10:10,552
THAT THE WAY YOU'VE SET UP HBCD

1826
01:10:10,552 --> 01:10:14,923
TO BE A PRECURSOR TO ABCD WHERE

1827
01:10:14,923 --> 01:10:16,224
WE'RE SORT OF BRIDGING THE GAP

1828
01:10:16,224 --> 01:10:17,659
FROM PRENATAL EXPOSURE THROUGH

1829
01:10:17,659 --> 01:10:19,394
TO AGE 9, THAT THERE WILL BE AN

1830
01:10:19,394 --> 01:10:21,563
OPPORTUNITY FOR THE ABCD

1831
01:10:21,563 --> 01:10:23,098
CHILDREN, YOUTH, TO ACTUALLY

1832
01:10:23,098 --> 01:10:24,733
BECOME PARENTS AND COME BACK

1833
01:10:24,733 --> 01:10:27,536
INTO HBCD WITH THIS INCREDIBLE

1834
01:10:27,536 --> 01:10:29,171
LONGITUDAL PERSPECTIVE.

1835
01:10:29,171 --> 01:10:30,806
SO NOT A COMMENT BUT A HOPE THAT

1836
01:10:30,806 --> 01:10:31,907
THESE TWO PROJECTS WILL SET US

1837
01:10:31,907 --> 01:10:33,942
UP TO HAVE AN OPPORTUNITY TO

1838
01:10:33,942 --> 01:10:36,678
JUST GO FULL CIRCLE AND

1839
01:10:36,678 --> 01:10:40,081
UNDERSTAND HOW ONE'S OWN

1840
01:10:40,081 --> 01:10:40,949
LIFETIME OF BRAIN DEVELOPMENT

1841
01:10:40,949 --> 01:10:42,884
AND EXPERIENCE KIND OF SHAPES

1842
01:10:42,884 --> 01:10:44,953
THEIR BECOMING A PARENT, THEIR

1843
01:10:44,953 --> 01:10:46,488
PRENATAL BEHAVIORS, AND THEIR

1844
01:10:46,488 --> 01:10:46,822
OFFSPRING.

1845
01:10:46,822 --> 01:10:50,292
I THINK THAT WOULD BE JUST AN

1846
01:10:50,292 --> 01:10:51,393
INCREDIBLE OPPORTUNITY BEYOND

1847
01:10:51,393 --> 01:10:52,594
WHAT PEOPLE HAVE ALREADY SET UP.

1848
01:10:52,594 --> 01:10:54,129
SO THANK YOU VERY MUCH FOR THESE

1849
01:10:54,129 --> 01:10:55,263
INCREDIBLE PROJECTS.

1850
01:10:55,263 --> 01:10:56,598
>> THANKS A LOT, AND
THANKS FOR

1851
01:10:56,598 --> 01:10:57,899
THE COMMENTS, AND I COMPLETELY

1852
01:10:57,899 --> 01:10:58,233
AGREE.

1853
01:10:58,233 --> 01:11:00,969
AND I DO HOPE THAT THE FUNDING

1854
01:11:00,969 --> 01:11:01,937
CONTINUES SO THAT WE CAN

1855
01:11:01,937 --> 01:11:03,038
ACTUALLY DO THAT.

1856
01:11:03,038 --> 01:11:06,508
I MEAN, IT WAS -- YOU SORT OF

1857
01:11:06,508 --> 01:11:09,110
SEE THE RICHNESS OF THE

1858
01:11:09,110 --> 01:11:11,880
INFORMATION THAT WE HAVE AND THE

1859
01:11:11,880 --> 01:11:13,215
COMMITMENT OF THESE TEENAGERS

1860
01:11:13,215 --> 01:11:16,685
AND THEIR FAMILIES TO IT SO IT

1861
01:11:16,685 --> 01:11:18,286
COULD BE A PITY NOT TO CONTINUE

1862
01:11:18,286 --> 01:11:20,489
WORKING ON IT.

1863
01:11:20,489 --> 01:11:22,791
BUT SO ABSOLUTELY, WE ARE VERY

1864
01:11:22,791 --> 01:11:25,393
AWARE THAT THESE HAVE BEEN

1865
01:11:25,393 --> 01:11:28,563
PROJECTS THAT EVEN OF COURSE A

1866
01:11:28,563 --> 01:11:31,066
PROJECT LIKE THAT ARE COSTLY IN

1867
01:11:31,066 --> 01:11:33,034
TERMS OF THE AMOUNT OF KNOWLEDGE

1868
01:11:33,034 --> 01:11:35,537
THAT THEY HAVE GENERATED.

1869
01:11:35,537 --> 01:11:36,972
IT HAS BEEN INCREDIBLY

1870
01:11:36,972 --> 01:11:42,878
SUCCESSFUL.

1871
01:11:42,878 --> 01:11:44,412
SO THANKS FOR BRINGING THIS UP.

1872
01:11:44,412 --> 01:11:45,347
ONE OF THE THINGS THAT I LOVE

1873
01:11:45,347 --> 01:11:50,619
ABOUT IT, IT EE EQUALIZING SCIE.

1874
01:11:50,619 --> 01:11:52,888
BECAUSE ME AS A RESEARCHER,

1875
01:11:52,888 --> 01:11:55,156
THROUGH THESE TYPE OF DATABASE,

1876
01:11:55,156 --> 01:11:57,459
ANYONE IN A SMALL COLLEGE OR IN

1877
01:11:57,459 --> 01:12:00,195
AN INSTITUTION THAT DOESN'T HAVE

1878
01:12:00,195 --> 01:12:01,563
THE CAPABILITIES CAN GET THEIR

1879
01:12:01,563 --> 01:12:03,164
HANDS ON IT AND TAKE ADVANTAGE

1880
01:12:03,164 --> 01:12:03,765
OF IT.

1881
01:12:03,765 --> 01:12:07,168
SO IT IS JUST A WONDERFUL -- AND

1882
01:12:07,168 --> 01:12:09,838
YES, ARPANA, I HOPE OUR BUDGET

1883
01:12:09,838 --> 01:12:12,807
KEEPS ON ROBUST AND THESE, OF

1884
01:12:12,807 --> 01:12:13,675
COURSE, ARE PRIORITY PROJECTS

1885
01:12:13,675 --> 01:12:20,882
FOR THE INSTITUTE.

1886
01:12:20,882 --> 01:12:21,082
KATE?

1887
01:12:21,082 --> 01:12:23,051
>> THANK YOU, NORA, FOR
ANOTHER

1888
01:12:23,051 --> 01:12:24,219
EXCELLENT MEETING AND EXCELLENT

1889
01:12:24,219 --> 01:12:25,654
PRESENTATION FULL OF SO MUCH

1890
01:12:25,654 --> 01:12:27,656
INTERESTING AND EXCITING

1891
01:12:27,656 --> 01:12:28,290
INFORMATION.

1892
01:12:28,290 --> 01:12:31,059
I WAS PARTICULARLY INTERESTED IN

1893
01:12:31,059 --> 01:12:32,460
THE TRENDS IN SUBSTANCE USE THAT

1894
01:12:32,460 --> 01:12:33,628
YOU SHARED.

1895
01:12:33,628 --> 01:12:35,030
I'M WONDERING -- MY QUESTION IS

1896
01:12:35,030 --> 01:12:38,099
ABOUT XYLAZINE, AND WHETHER THE

1897
01:12:38,099 --> 01:12:40,735
USE OF XYLAZINE WITH FENTANYL IN

1898
01:12:40,735 --> 01:12:42,437
PARTICULAR IS TRACKING ALONG

1899
01:12:42,437 --> 01:12:43,638
WITH THE INCREASES THAT YOU

1900
01:12:43,638 --> 01:12:44,105
SHARED.

1901
01:12:44,105 --> 01:12:47,042
AND ALSO WANT TO CONGRATULATE

1902
01:12:47,042 --> 01:12:48,343
DR. MONTOYA ON HIS VERY

1903
01:12:48,343 --> 01:12:50,645
WELL-DESERVED PROMOTION.

1904
01:12:50,645 --> 01:12:52,614
>> THANKS, KATE, AND
THANKS FOR

1905
01:12:52,614 --> 01:12:53,982
HELPING IN THE SEARCH COMMITTEE.

1906
01:12:53,982 --> 01:12:55,216
SO I'M VERY, VERY GRATEFUL FOR

1907
01:12:55,216 --> 01:12:56,751
YOU.

1908
01:12:56,751 --> 01:13:02,290
AND YES, WE HAVE SEEN, I MEAN,

1909
01:13:02,290 --> 01:13:06,328
THE TTHE RATE IN WHICH WE'RE SEG

1910
01:13:06,328 --> 01:13:08,396
OVERDOSE DEATHS WITH FENTANYL

1911
01:13:08,396 --> 01:13:09,464
VERSUS FENTANYL WITH XYLAZINE,

1912
01:13:09,464 --> 01:13:11,866
THE RELATIVE PROPORTION VARIES

1913
01:13:11,866 --> 01:13:12,968
SIGNIFICANT BY GEOGRAPHICAL

1914
01:13:12,968 --> 01:13:15,537
AREA, AND IT'S MUCH HIGHER IN

1915
01:13:15,537 --> 01:13:17,105
THE EAST COAST THAN IN THE WEST

1916
01:13:17,105 --> 01:13:20,375
COAST, BUT WHAT HAS BEEN

1917
01:13:20,375 --> 01:13:23,111
REPORTED IS THAT BASICALLY

1918
01:13:23,111 --> 01:13:25,080
THE -- THAT IT IS EMERGING NOW

1919
01:13:25,080 --> 01:13:27,349
ALMOST ON EVERY SINGLE STATE,

1920
01:13:27,349 --> 01:13:30,318
THERE HAVE BEEN REPORTS OF

1921
01:13:30,318 --> 01:13:31,052
FATALITIES ASSOCIATED WITH THE

1922
01:13:31,052 --> 01:13:34,556
USE OF BOTH DRUGS.

1923
01:13:34,556 --> 01:13:35,757
AND IT HAS BEEN IN GROWING AND

1924
01:13:35,757 --> 01:13:37,592
IN SOME PLACES LIKE

1925
01:13:37,592 --> 01:13:39,794
PENNSYLVANIA, I THINK SORT OF --

1926
01:13:39,794 --> 01:13:42,864
ALMOST LIKE 70% IN SOME

1927
01:13:42,864 --> 01:13:44,132
INSTANCES CONTAINED XYLAZINE.

1928
01:13:44,132 --> 01:13:46,001
SO THERE'S TREMENDOUS

1929
01:13:46,001 --> 01:13:46,968
VARIABILITY BY GEOGRAPHIC

1930
01:13:46,968 --> 01:13:50,372
LOCATION.

1931
01:13:50,372 --> 01:13:52,907
IT HAS MADE IT MUCH MORE COMPLEX

1932
01:13:52,907 --> 01:13:55,276
TO UNDERSTAND THE PATTERNS,

1933
01:13:55,276 --> 01:13:57,245
BECAUSE WE DON'T ACTUALLY EVEN

1934
01:13:57,245 --> 01:14:00,548
UNDERSTAND XYLAZINE WELL.

1935
01:14:00,548 --> 01:14:04,986
AND SO WE KNOW THAT NALOXONE BY

1936
01:14:04,986 --> 01:14:09,691
ITSELF IN SOME INSTANCES MAY NOT

1937
01:14:09,691 --> 01:14:11,693
BE SUFFICIENT BUT IT IS CRUCIAL

1938
01:14:11,693 --> 01:14:12,861
TO ADMINISTER IT BECAUSE IT

1939
01:14:12,861 --> 01:14:14,396
ACTUALLY HELPS, BUT IT'S NOT

1940
01:14:14,396 --> 01:14:15,830
SUFFICIENT BECAUSE PATIENTS ARE

1941
01:14:15,830 --> 01:14:19,734
STILL VERY, VERY HYPOTENSIVE AND

1942
01:14:19,734 --> 01:14:21,136
HYPOXEMIA LASTS MUCH LONGER.

1943
01:14:21,136 --> 01:14:22,671
AND THE OTHER ISSUE THAT HAS

1944
01:14:22,671 --> 01:14:26,041
GENERATED A LOT OF CONCERN IS

1945
01:14:26,041 --> 01:14:26,808
THESE HORRIBLE LESIONS THAT

1946
01:14:26,808 --> 01:14:29,444
HAPPEN IN THE SKIN OF PEOPLE

1947
01:14:29,444 --> 01:14:30,979
THAT GET EXPOSED TO THIS

1948
01:14:30,979 --> 01:14:32,447
COMBINATION OF FENTANYL WITH

1949
01:14:32,447 --> 01:14:34,115
XYLAZINE OR XYLAZINE WITH

1950
01:14:34,115 --> 01:14:34,849
HEROIN.

1951
01:14:34,849 --> 01:14:37,919
WE DON'T UNDERSTAND, I MEAN,

1952
01:14:37,919 --> 01:14:39,454
THERE'S OBVIOUSLY HYPOTHESIS

1953
01:14:39,454 --> 01:14:40,755
ABOUT WHAT MAY BE GOING ON WITH

1954
01:14:40,755 --> 01:14:43,258
THESE LESIONS, BECAUSE THEY GROW

1955
01:14:43,258 --> 01:14:45,026
VERY FAST, THEY ARE NOT A

1956
01:14:45,026 --> 01:14:46,327
TYPICAL TYPE OF LESION THAT YOU

1957
01:14:46,327 --> 01:14:48,063
OBSERVE WITH OTHER -- IN OTHER

1958
01:14:48,063 --> 01:14:50,165
CASES OF INJECTION DRUG USE, AND

1959
01:14:50,165 --> 01:14:51,466
SOMETIMES THEY APPEAR IN AREAS

1960
01:14:51,466 --> 01:14:52,801
THAT THEY DON'T INJECT.

1961
01:14:52,801 --> 01:14:53,902
LIKE YOU CAN SEE THEM EVEN IN

1962
01:14:53,902 --> 01:14:56,938
THE BACK.

1963
01:14:56,938 --> 01:14:59,908
SO IT IS BELIEVED THAT THE

1964
01:14:59,908 --> 01:15:03,244
HYPOXEMIA FROM THE RESPIRATORY

1965
01:15:03,244 --> 01:15:05,113
PRESENT EFFECTS COUPLED TO THE

1966
01:15:05,113 --> 01:15:07,749
HYPOTENSION FROM XYLAZINE

1967
01:15:07,749 --> 01:15:11,219
ACTUALLY EXACERBATES TISSUE

1968
01:15:11,219 --> 01:15:12,253
IRRIGATION, THAT THE SEDATIVE

1969
01:15:12,253 --> 01:15:15,690
EFFECTS OF THAT COMBINATION

1970
01:15:15,690 --> 01:15:17,325
ACTUALLY LEADS TO PRESSURE

1971
01:15:17,325 --> 01:15:18,493
LESIONS BECAUSE PEOPLE ARE

1972
01:15:18,493 --> 01:15:19,494
SEDATED FOR HOURS, DON'T MOVE,

1973
01:15:19,494 --> 01:15:23,665
BUT IT'S ALSO BEING POSTULATED

1974
01:15:23,665 --> 01:15:25,700
THAT PERHAPS -- AND THIS IS A

1975
01:15:25,700 --> 01:15:29,304
VERY INTERESTING THOUGHT -- THAT

1976
01:15:29,304 --> 01:15:31,206
KAPPA RECEPTOR AGONIST EFFECTS

1977
01:15:31,206 --> 01:15:39,280
OF XYLAZINE MAY CONTRIBUTE, AND

1978
01:15:39,280 --> 01:15:40,348
PARTICULARLY IF YOU CONSIDER

1979
01:15:40,348 --> 01:15:42,517
FENTANYL ALSO HAS SOME XYLAZINE

1980
01:15:42,517 --> 01:15:46,154
AGONIST EFFECTS, AND SO WE DON'T

1981
01:15:46,154 --> 01:15:47,322
REALLY -- OBVIOUSLY WE'RE ASKING

1982
01:15:47,322 --> 01:15:51,059
RESEARCHERS TO LOOK INTO IT, THE

1983
01:15:51,059 --> 01:15:52,694
FDA IS WORKING WITH ANIMAL

1984
01:15:52,694 --> 01:15:54,329
MODELS FOR THESE LESIONS BECAUSE

1985
01:15:54,329 --> 01:15:55,930
IF YOU HAVE THEM, THEN YOU COULD

1986
01:15:55,930 --> 01:15:57,699
TRY TO TEST DIFFERENT

1987
01:15:57,699 --> 01:16:01,102
INTERVENTIONS TO TACKLE IT.

1988
01:16:01,102 --> 01:16:02,470
SO DIFFERENT INTERVENTIONS TO

1989
01:16:02,470 --> 01:16:03,671
TACKLE THE OVERDOSES THAT THEY

1990
01:16:03,671 --> 01:16:05,106
HAPPEN TO SAVE THEM, BUT ALSO

1991
01:16:05,106 --> 01:16:08,176
THIS VERY CHALLENGING PROBLEM

1992
01:16:08,176 --> 01:16:09,778
THAT IS ACTUALLY RESULTING --

1993
01:16:09,778 --> 01:16:11,846
I'VE MET WITH PEOPLE THAT HAD AN

1994
01:16:11,846 --> 01:16:13,181
AMPUTATION FROM IT, AND THEY ARE

1995
01:16:13,181 --> 01:16:13,681
DESPERATE.

1996
01:16:13,681 --> 01:16:14,883
THEY BASE INCLUDE -- THIS IS ONE

1997
01:16:14,883 --> 01:16:16,184
OF THE THINGS THEY WANT TO KNOW,

1998
01:16:16,184 --> 01:16:18,686
WHEN YOU ASK THEM, HOW CAN

1999
01:16:18,686 --> 01:16:20,455
RESEARCH HELP YOU, TO PEOPLE

2000
01:16:20,455 --> 01:16:22,624
THAT ARE TAKING DRUGS, WHAT IS

2001
01:16:22,624 --> 01:16:24,793
XYLAZINE DOING TO OUR BODIES, TO

2002
01:16:24,793 --> 01:16:27,128
OUR LUNGS, HOW TO TREAT THE SKIN

2003
01:16:27,128 --> 01:16:28,196
LESIONS.

2004
01:16:28,196 --> 01:16:31,065
SO YES.

2005
01:16:31,065 --> 01:16:36,971
MELANIE.

2006
01:16:36,971 --> 01:16:40,108
YOU ARE MUTED, MELANIE.

2007
01:16:40,108 --> 01:16:40,408
MELANIE --

2008
01:16:40,408 --> 01:16:41,075
>> LIKE USUAL.

2009
01:16:41,075 --> 01:16:41,743
THANK YOU.

2010
01:16:41,743 --> 01:16:43,278
NO, THANK YOU, NORA.

2011
01:16:43,278 --> 01:16:45,013
GREAT TALK.

2012
01:16:45,013 --> 01:16:46,114
SORRY FOR FOR GETTING THAT I'M

2013
01:16:46,114 --> 01:16:47,849
MUTED.

2014
01:16:47,849 --> 01:16:53,021
I WAS VERY IMPRESSED BY THE NEW

2015
01:16:53,021 --> 01:16:54,522
CHEMICAL ADDICTION TREATMENTS

2016
01:16:54,522 --> 01:16:58,359
LIKE CS1103 AND POTENTIALLY

2017
01:16:58,359 --> 01:16:59,027
FENTANYL SEQUESTERS THAT WERE

2018
01:16:59,027 --> 01:17:00,428
MENTIONED BEFORE, AND I WANTED

2019
01:17:00,428 --> 01:17:05,567
JUST TO SORT OF SEE HOW YOU SEE

2020
01:17:05,567 --> 01:17:06,835
OVERALL THEM AND POTENTIALLY

2021
01:17:06,835 --> 01:17:08,503
OTHERS INCLUDING POSSIBLY THE

2022
01:17:08,503 --> 01:17:11,573
GLP AGONIST, YOU KNOW,

2023
01:17:11,573 --> 01:17:13,141
TREATMENTS RESHAPING HOW WE ARE

2024
01:17:13,141 --> 01:17:16,077
GOING TO TREAT IN THE FUTURE.

2025
01:17:16,077 --> 01:17:18,446
>> YEAH, NO, WE ARE VERY
EXCITED

2026
01:17:18,446 --> 01:17:20,949
AND I THINK WHEN YOU'RE SPEAKING

2027
01:17:20,949 --> 01:17:28,056
ABOUT SCWES TRA SCW SEQUESTERS N

2028
01:17:28,056 --> 01:17:29,357
REVERSE AN OVERDOSE, YOU KNOW

2029
01:17:29,357 --> 01:17:31,226
THAT WITH NALOXONE, YOU ACTUALLY

2030
01:17:31,226 --> 01:17:32,760
STILL HAVE A LONGER LASTING

2031
01:17:32,760 --> 01:17:34,629
EFFECT OF FENTANYL.

2032
01:17:34,629 --> 01:17:36,798
SO IF YOU COMBINE THE NALOXONE

2033
01:17:36,798 --> 01:17:38,132
WITH A SCWES TRANT, YOU'RE MUCH

2034
01:17:38,132 --> 01:17:39,868
MORE LIKELY TO BE SUCCESSFUL.

2035
01:17:39,868 --> 01:17:41,069
AND THERE'S SOME DATA TO SHOW

2036
01:17:41,069 --> 01:17:41,469
THAT.

2037
01:17:41,469 --> 01:17:43,471
THE SAME THING WITH

2038
01:17:43,471 --> 01:17:44,105
METHAMPHETAMINE, WE ABSOLUTELY

2039
01:17:44,105 --> 01:17:48,409
HAVE NOTHING RIGHT NOW WITH A

2040
01:17:48,409 --> 01:17:48,977
METHAMPHETAMINE OVERDOSE.

2041
01:17:48,977 --> 01:17:52,080
SO TO HAVE ALTERNATIVES IS

2042
01:17:52,080 --> 01:17:58,219
NECESSARY THERE ARE MULTIPLE

2043
01:17:58,219 --> 01:17:59,721
SORT OF STRATEGIES BEING

2044
01:17:59,721 --> 01:18:00,788
DEPLOYED WHICH WE HAVE BEEN ABLE

2045
01:18:00,788 --> 01:18:01,689
TO DO BECAUSE OF THE EXTRA FUNDS

2046
01:18:01,689 --> 01:18:04,759
THAT WERE ALLOCATED UNDER THE

2047
01:18:04,759 --> 01:18:06,361
HEAL MISSION OF ADDRESSING THE

2048
01:18:06,361 --> 01:18:07,896
OVERDOSE CRISIS.

2049
01:18:07,896 --> 01:18:10,398
I THINK THAT IF YOU LOOK AT IT

2050
01:18:10,398 --> 01:18:13,501
FROM TIME LINES, WE TRIED TO

2051
01:18:13,501 --> 01:18:14,903
ACCELERATE AS MUCH AS POSSIBLE

2052
01:18:14,903 --> 01:18:16,738
FROM -- BUT FROM THAT

2053
01:18:16,738 --> 01:18:20,174
PERSPECTIVE, WHEN YOU HAVE A

2054
01:18:20,174 --> 01:18:21,776
PROBLEM THAT IS ALREADY THERE IN

2055
01:18:21,776 --> 01:18:23,211
THE -- A PRODUCT ALREADY IN THE

2056
01:18:23,211 --> 01:18:26,247
MARKET AND YOU FIND REPURPOSING,

2057
01:18:26,247 --> 01:18:27,115
YOU OF COURSE GET MUCH MORE

2058
01:18:27,115 --> 01:18:27,448
EXCITED.

2059
01:18:27,448 --> 01:18:31,719
SO WE ARE EXTREMELY EXCITED

2060
01:18:31,719 --> 01:18:34,322
ABOUT THE GLP AGONIST BECAUSE

2061
01:18:34,322 --> 01:18:35,323
ANIMALS SHOW VERY POSITIVE

2062
01:18:35,323 --> 01:18:36,824
EFFECTS IN TERMS OF PREVENTING

2063
01:18:36,824 --> 01:18:38,960
DRUG ADMINISTRATION AND RELAPSE,

2064
01:18:38,960 --> 01:18:41,296
AND THE CLINICAL DATA, THE

2065
01:18:41,296 --> 01:18:43,498
ANECDOTES AND THE ANALYSIS ON

2066
01:18:43,498 --> 01:18:45,800
ELECTRONIC HEALTH RECORDS IS

2067
01:18:45,800 --> 01:18:48,836
DOCUMENTED TO RISK CONSUMPTION.

2068
01:18:48,836 --> 01:18:51,239
SO YES, THIS IS AN AREA THAT IS

2069
01:18:51,239 --> 01:18:52,674
EXACTLY PARTICULARLY EXCITING

2070
01:18:52,674 --> 01:18:53,908
BECAUSE DRUGS HAVE BEEN APPROVED

2071
01:18:53,908 --> 01:18:55,176
FOR OTHER INDICATIONS, IT WILL

2072
01:18:55,176 --> 01:18:56,711
BE MUCH FASTER TO BRING INTO THE

2073
01:18:56,711 --> 01:19:01,649
CLINIC.

2074
01:19:01,649 --> 01:19:05,453
SO SO THAT THAT IS AGAIN AN ARE.

2075
01:19:05,453 --> 01:19:08,156
SO WE ARE PURSUING MEDICATIONS

2076
01:19:08,156 --> 01:19:10,792
FOR NEW INDICATIONS AND WE'RE

2077
01:19:10,792 --> 01:19:11,893
PURSUING COMPLETELY NEW TARGETS,

2078
01:19:11,893 --> 01:19:15,063
NEW FORMULATIONS.

2079
01:19:15,063 --> 01:19:16,564
 -- ANTIBODIES, AND WE'RE ALSO

2080
01:19:16,564 --> 01:19:18,967
VERY EXCITED ABOUT

2081
01:19:18,967 --> 01:19:20,435
NEUROMODULATION APPROACHES WHICH

2082
01:19:20,435 --> 01:19:22,370
ARE REVEALING SOME REALLY

2083
01:19:22,370 --> 01:19:23,538
EXCITING RESULTS, PARTICULARLY

2084
01:19:23,538 --> 01:19:25,306
WITH THE USE OF ULTRASOUND.

2085
01:19:25,306 --> 01:19:27,809
SO THERE IS A LOT OF VERY

2086
01:19:27,809 --> 01:19:31,980
PROMISING WORK GOING ON.

2087
01:19:31,980 --> 01:19:35,917
>> THANK YOU.

2088
01:19:35,917 --> 01:19:36,551
>> CHARLES.

2089
01:19:36,551 --> 01:19:38,086
>> I WAS VERY IMPRESSED BY
THE

2090
01:19:38,086 --> 01:19:40,788
DATA THAT YOU'VE GOT ON THE

2091
01:19:40,788 --> 01:19:41,689
NEURODEVELOPMENT FOR CHILDREN

2092
01:19:41,689 --> 01:19:44,192
AND RISKS FOR MARIJUANA USE, AND

2093
01:19:44,192 --> 01:19:45,360
IT'S A BIG CONCERN.

2094
01:19:45,360 --> 01:19:47,328
NOT REALLY KNOWING HOW TO MOVE

2095
01:19:47,328 --> 01:19:48,429
IT FORWARD.

2096
01:19:48,429 --> 01:19:50,531
AND ALSO, RAJITA'S COMMENT ABOUT

2097
01:19:50,531 --> 01:19:52,600
SAFE LEVELS, I THINK IS REALLY

2098
01:19:52,600 --> 01:19:54,002
SOMETHING THAT NIDA COULD BE IN

2099
01:19:54,002 --> 01:19:56,504
A POSITION TO REALLY VERY

2100
01:19:56,504 --> 01:19:57,071
CONSTRUCTIVELY ADDRESS.

2101
01:19:57,071 --> 01:20:00,675
I REALLY LIKE THAT IDEA.

2102
01:20:00,675 --> 01:20:01,876
THE CREDIBILITY OF SCIENCE

2103
01:20:01,876 --> 01:20:04,612
REQUIRES THAT PEOPLE SAY YES,

2104
01:20:04,612 --> 01:20:07,015
SAFE LEVELS MIGHT EXIST, AND

2105
01:20:07,015 --> 01:20:07,882
THAT'S THEIR EXPERIENCE, BUT

2106
01:20:07,882 --> 01:20:09,083
WHEN WE READ IN THE NEWSPAPERS

2107
01:20:09,083 --> 01:20:12,053
THE STORIES ABOUT HOW THERE ARE

2108
01:20:12,053 --> 01:20:14,222
NOW THOUGHT TO BE NO SAFE LEVELS

2109
01:20:14,222 --> 01:20:16,190
FOR WINE CONSUMPTION, NO SAFE

2110
01:20:16,190 --> 01:20:17,959
LEVELS FOR ALCOHOL CONSUMPTION,

2111
01:20:17,959 --> 01:20:20,895
THERE REALLY IS A CONFLICT

2112
01:20:20,895 --> 01:20:22,196
BETWEEN THOSE REPORTS OF NO SAFE

2113
01:20:22,196 --> 01:20:24,599
LEVELS AND PEOPLE'S EXPERIENCE

2114
01:20:24,599 --> 01:20:26,134
WHERE A BEER EVERY ONCE IN A

2115
01:20:26,134 --> 01:20:27,435
WHILE SEEMS TO BE SAFE.

2116
01:20:27,435 --> 01:20:29,404
AND SO I DON'T KNOW HOW TO

2117
01:20:29,404 --> 01:20:30,505
POLITICALLY WALK THAT LINE.

2118
01:20:30,505 --> 01:20:32,607
IT SOUNDS LIKE A VERY DIFFICULT

2119
01:20:32,607 --> 01:20:35,309
LINE TO ADDRESS, AND COMING BACK

2120
01:20:35,309 --> 01:20:38,246
TO A SPECIFIC SUGGESTION, IT

2121
01:20:38,246 --> 01:20:40,314
SEEMS TO ME THAT WE HAVE AN

2122
01:20:40,314 --> 01:20:42,817
OPPORTUNITY TO TRY TO GIVE

2123
01:20:42,817 --> 01:20:44,919
PATIENTS, PERSONS, MORE DATA

2124
01:20:44,919 --> 01:20:46,854
ABOUT THEIR HARMFUL DRUG USE.

2125
01:20:46,854 --> 01:20:48,723
I KNOW THAT WHEN I GO SEE MY

2126
01:20:48,723 --> 01:20:50,358
PRIMARY CARE PHYSICIAN, I HAVE

2127
01:20:50,358 --> 01:20:52,760
TO ANSWER A QUESTION OF HOW MUCH

2128
01:20:52,760 --> 01:20:56,364
ALCOHOL AM I COU CONSUMING, ANDF

2129
01:20:56,364 --> 01:20:57,231
COURSE PHYSICIANS BELIEVE THAT

2130
01:20:57,231 --> 01:20:58,533
MOST PERSONS ARE LYING ABOUT

2131
01:20:58,533 --> 01:20:59,967
THEIR CONSUMPTION, THEY

2132
01:20:59,967 --> 01:21:01,135
UNDERESTIMATE, THEY UNDERREPORT

2133
01:21:01,135 --> 01:21:01,602
WHAT THEY DO.

2134
01:21:01,602 --> 01:21:03,805
IT SEEMS TO ME THAT IF WE HAD

2135
01:21:03,805 --> 01:21:06,641
OBJECTIVE BLOOD LEVELS,

2136
01:21:06,641 --> 01:21:07,942
BIOMARKERS THAT COULD DOCUMENT

2137
01:21:07,942 --> 01:21:10,344
WHAT, IN FACT, WE ARE, IN FACT,

2138
01:21:10,344 --> 01:21:12,847
CONSUMING, WHEN I LOOK AT, FOR

2139
01:21:12,847 --> 01:21:14,282
EXAMPLE, ARE THERE BIOMARKERS

2140
01:21:14,282 --> 01:21:15,683
FOR ALCOHOL CONSUMPTION, THE

2141
01:21:15,683 --> 01:21:18,886
ANSWER IS YES, THERE ARE.

2142
01:21:18,886 --> 01:21:20,621
THEY'RE NOT WIDELY USED BUT THEY

2143
01:21:20,621 --> 01:21:21,956
COULD SIMPLY HELP US GET A

2144
01:21:21,956 --> 01:21:24,792
BETTER SENSE AS A PATIENT OR AS

2145
01:21:24,792 --> 01:21:27,829
A PERSON REGULARLY HOW DOES OUR

2146
01:21:27,829 --> 01:21:30,998
ALCOHOL CONSUMPTION COMPARE TO

2147
01:21:30,998 --> 01:21:31,232
OTHERS?

2148
01:21:31,232 --> 01:21:32,567
IF WE HAVE AN OBJECTIVE MEASURE

2149
01:21:32,567 --> 01:21:33,734
OF WHAT KIND OF ALCOHOL

2150
01:21:33,734 --> 01:21:37,205
CONSUMPTION WE HAVE IN RELATION

2151
01:21:37,205 --> 01:21:40,508
TO HEALTH RISK, IT WILL BE MUCH

2152
01:21:40,508 --> 01:21:42,543
LIKE WHEN WE GET OUR CHOLESTEROL

2153
01:21:42,543 --> 01:21:44,078
BLOOD LEVELS CHECKED, THERE ARE

2154
01:21:44,078 --> 01:21:45,179
VALIDATED MEASURES FOR

2155
01:21:45,179 --> 01:21:46,714
CHOLESTEROL, AND IF WE KNOW OUR

2156
01:21:46,714 --> 01:21:49,350
LEVEL IS HIGH, WE'VE GOT RISK OF

2157
01:21:49,350 --> 01:21:50,318
HEART DISEASE, THAT'S ALL

2158
01:21:50,318 --> 01:21:50,885
OBJECTIVE.

2159
01:21:50,885 --> 01:21:52,720
IF WE HAD MEASURES LIKE THAT FOR

2160
01:21:52,720 --> 01:21:54,055
ALCOHOL, IT WOULD BE VERY

2161
01:21:54,055 --> 01:21:55,556
HELPFUL SINCE SO MANY

2162
01:21:55,556 --> 01:21:57,091
INDIVIDUALS USE ALCOHOL AND

2163
01:21:57,091 --> 01:21:58,860
UNDERREPORT THEIR CONSUMPTION,

2164
01:21:58,860 --> 01:22:00,928
BUT FROM NIDA PERSPECTIVE, FROM

2165
01:22:00,928 --> 01:22:03,831
A PUBLIC HEALTH PERSPECTIVE, IS

2166
01:22:03,831 --> 01:22:07,135
THERE ANY USE IN HAVING NIDA

2167
01:22:07,135 --> 01:22:08,302
VALIDATE BIOMARKERS THAT COULD

2168
01:22:08,302 --> 01:22:10,571
BE USEFUL AS A DRUG SCREENING

2169
01:22:10,571 --> 01:22:12,373
THAT WOULD BE ROUTINELY

2170
01:22:12,373 --> 01:22:14,909
INCORPORATED INTO A HEALTH

2171
01:22:14,909 --> 01:22:15,877
CHECK, WHERE INDIVIDUALS WHO

2172
01:22:15,877 --> 01:22:21,482
COME TO THEIR PHYSICIAN, FOR AN

2173
01:22:21,482 --> 01:22:22,450
ANNUAL HEALTH CHECK, JUST TO GET

2174
01:22:22,450 --> 01:22:23,885
A SENSE OF WHERE ARE THEY ON A

2175
01:22:23,885 --> 01:22:25,186
SCALE OF DRUG USE, AND ARE THEY

2176
01:22:25,186 --> 01:22:29,023
IN A RISKY POSITION, AND

2177
01:22:29,023 --> 01:22:30,224
COULD -- I'M NOT SUGGESTING THAT

2178
01:22:30,224 --> 01:22:34,695
THIS BE REPORTED TO THE POLICE,

2179
01:22:34,695 --> 01:22:36,330
BUT IN TERMS OF PRIVATE

2180
01:22:36,330 --> 01:22:37,865
CONVERSATIONS WITH THEIR PRIMARY

2181
01:22:37,865 --> 01:22:39,934
CARE PHYSICIANS, COULD A

2182
01:22:39,934 --> 01:22:44,005
VALIDATED TEST FOR DRUG USE BE

2183
01:22:44,005 --> 01:22:44,972
CONSTRUCTIVE IN WAYS THAT ALLOWS

2184
01:22:44,972 --> 01:22:46,507
A PHYSICIAN TO DO MORE THAN JUST

2185
01:22:46,507 --> 01:22:47,608
SIMPLY ASK WHAT IS YOUR

2186
01:22:47,608 --> 01:22:49,810
CONSUMPTION AND GET A VERBAL

2187
01:22:49,810 --> 01:22:51,779
REPORT, BUT ACTUALLY HAVE AN

2188
01:22:51,779 --> 01:22:52,747
OBJECTIVE MEASURE THAT COULD

2189
01:22:52,747 --> 01:22:56,384
THEN BE VALIDATED AND SAY NO, I

2190
01:22:56,384 --> 01:22:57,919
THINK YOUR MARIJUANA USE IS IN

2191
01:22:57,919 --> 01:22:59,220
THE RISKY CATEGORY.

2192
01:22:59,220 --> 01:23:02,390
AND I THINK WE NEED TO REPORT TO

2193
01:23:02,390 --> 01:23:04,592
YOU THAT THIS IS SOMETHING WE

2194
01:23:04,592 --> 01:23:06,827
NEED TO TALK ABOUT IN A WAY THAT

2195
01:23:06,827 --> 01:23:08,062
IS A HELPFUL SETTING.

2196
01:23:08,062 --> 01:23:09,163
BECAUSE RIGHT NOW WE DO HAVE

2197
01:23:09,163 --> 01:23:11,999
THAT KIND OF OBJECTIVE DATA.

2198
01:23:11,999 --> 01:23:13,634
JUST CONVERSATIONS THAT ARE JUST

2199
01:23:13,634 --> 01:23:15,203
NOT SATISFACTORY.

2200
01:23:15,203 --> 01:23:17,438
BUT THAT'S SIMPLY MY THOUGHT.

2201
01:23:17,438 --> 01:23:19,440
>> NO, AND I AGREE,
CHARLES, I

2202
01:23:19,440 --> 01:23:21,542
MEAN, I THINK IT WOULD BE REALLY

2203
01:23:21,542 --> 01:23:23,611
FANTASTIC TO HAVE SUCH A TEST,

2204
01:23:23,611 --> 01:23:25,246
BECAUSE IT WILL BASICALLY MAKE

2205
01:23:25,246 --> 01:23:27,348
IT ALMOST AUTOMATIC THAT YOU

2206
01:23:27,348 --> 01:23:29,083
WOULD BE EVALUATED, JUST LIKE

2207
01:23:29,083 --> 01:23:31,719
YOU SAY, YOU WILL GET YOUR BLOOD

2208
01:23:31,719 --> 01:23:33,287
TEST AND THEY EVALUATE YOU.

2209
01:23:33,287 --> 01:23:37,024
I THINK THAT IN TERMS OF WITH

2210
01:23:37,024 --> 01:23:38,226
ALCOHOL, WHAT'S INTERESTING IS

2211
01:23:38,226 --> 01:23:39,293
THAT WHILE THERE ARE TESTS THAT

2212
01:23:39,293 --> 01:23:41,796
HAVE BEEN PROPOSED, NONETHELESS,

2213
01:23:41,796 --> 01:23:43,331
ONE THAT HAS BEEN USED BY A LOT

2214
01:23:43,331 --> 01:23:46,367
OF CLINICIANS TO TRY TO GAUGE

2215
01:23:46,367 --> 01:23:48,035
THE EXTENT TO WHICH THERE IS

2216
01:23:48,035 --> 01:23:49,570
HARMFUL EFFECTS ARE LIVER

2217
01:23:49,570 --> 01:23:50,871
FUNCTION TESTS, BECAUSE THAT

2218
01:23:50,871 --> 01:23:51,739
BASICALLY INDICATES WHEN SOMEONE

2219
01:23:51,739 --> 01:23:53,307
MAY BE CONSUMING ALCOHOL AT

2220
01:23:53,307 --> 01:23:56,010
LEVELS THAT ARE REFLECTED IN THE

2221
01:23:56,010 --> 01:23:57,778
MARKER THAT YOU CAN MONITOR.

2222
01:23:57,778 --> 01:23:59,447
SO EVEN THOUGH IT'S NOT THE ONLY

2223
01:23:59,447 --> 01:24:03,251
THING THAT IS GOING TO MAKE YOUR

2224
01:24:03,251 --> 01:24:04,785
LIVER FUNCTION TEST ABNORMAL, IT

2225
01:24:04,785 --> 01:24:09,924
IS THE MOST FREQUENTLY ONE.

2226
01:24:09,924 --> 01:24:12,293
SO WE SHOULD BASICALLY -- IT

2227
01:24:12,293 --> 01:24:14,395
WOULD BE IDEAL AND BUILDING --

2228
01:24:14,395 --> 01:24:17,231
AGAIN, IN A WAY THAT NEED THAT

2229
01:24:17,231 --> 01:24:20,635
WE HAVE TO BUILD UP KNOWLEDGE OF

2230
01:24:20,635 --> 01:24:26,641
WHAT COULD BE A BIOMARKER FOR

2231
01:24:26,641 --> 01:24:28,109
EXPOSURE TO DRUGS, SPECIFICALLY

2232
01:24:28,109 --> 01:24:30,177
SPEAKING IN TERMS OF CANNABIS,

2233
01:24:30,177 --> 01:24:33,314
BECAUSE THAT IS RIGHT NOW THE

2234
01:24:33,314 --> 01:24:37,485
MOST URGENT, JUST ON THE BASIS

2235
01:24:37,485 --> 01:24:39,120
OF THE HIGH PREVALENCE AND

2236
01:24:39,120 --> 01:24:41,088
INCREASED UTILIZATION BY MANY

2237
01:24:41,088 --> 01:24:44,258
PEOPLE, AND WE DON'T REALLY KNOW

2238
01:24:44,258 --> 01:24:47,962
TO WHAT EXTENT THERE ARE ADVERSE

2239
01:24:47,962 --> 01:24:48,496
OUTCOMES.

2240
01:24:48,496 --> 01:24:50,164
SO UNDERSTANDING WHAT ARE THE

2241
01:24:50,164 --> 01:24:51,899
ADVERSE OUTCOMES AND AT WHAT

2242
01:24:51,899 --> 01:24:53,134
THRESHOLD IS A KEY IN ORDER TO

2243
01:24:53,134 --> 01:24:56,937
BE ABLE TO PLACE IN TERMS OF

2244
01:24:56,937 --> 01:24:59,006
WHAT COULD POTENTIALLY BE A

2245
01:24:59,006 --> 01:25:01,309
BIOMARKER THAT IT'S INDICATIVE

2246
01:25:01,309 --> 01:25:03,210
OF RISK.

2247
01:25:03,210 --> 01:25:05,813
SO IT'S VERY MUCH LINKED WITH A

2248
01:25:05,813 --> 01:25:07,915
SUGGESTION THAT RAJITA HAD FOR A

2249
01:25:07,915 --> 01:25:08,349
THRESHOLD.

2250
01:25:08,349 --> 01:25:11,519
AND I DO THINK IT WOULD BE

2251
01:25:11,519 --> 01:25:12,386
EXTREMELY CONSEQUENTIAL TO HAVE

2252
01:25:12,386 --> 01:25:16,424
SUCH A BIOMARKER THAT COULD BE

2253
01:25:16,424 --> 01:25:18,426
DEPLOYED IN MEDICINE, BECAUSE

2254
01:25:18,426 --> 01:25:21,562
ONE OF THE ASPECTS I'VE BEEN

2255
01:25:21,562 --> 01:25:23,564
TRYING TO CHANGE IS THE NEGLECT

2256
01:25:23,564 --> 01:25:26,267
OF SCREENING FOR SUBSTANCE USE

2257
01:25:26,267 --> 01:25:28,035
AMONG MANY PRIMARY CARE

2258
01:25:28,035 --> 01:25:29,337
PHYSICIANS, AND HAVING SUCH A

2259
01:25:29,337 --> 01:25:33,641
TEST WILL MAKE IT OUGHT MATT

2260
01:25:33,641 --> 01:25:35,676
TICK.

2261
01:25:35,676 --> 01:25:36,110
 AUTOMATIC.

2262
01:25:36,110 --> 01:25:37,311
SO WE WILL PULL OUR HEADS

2263
01:25:37,311 --> 01:25:38,079
TOGETHER IN TERMS OF WHAT ARE

2264
01:25:38,079 --> 01:25:40,614
THE MECHANISMS WE COULD USE TO

2265
01:25:40,614 --> 01:25:43,451
TRY TO ACCELERATE THIS SPACE, IN

2266
01:25:43,451 --> 01:25:45,686
THIS CASE FOR EXAMPLE,

2267
01:25:45,686 --> 01:25:47,154
TRANSLATION AND INNOVATION, HOW

2268
01:25:47,154 --> 01:25:49,457
DO WE ENCOURAGE RESEARCHERS TO

2269
01:25:49,457 --> 01:25:51,325
GENERATE BIOMARKERS?

2270
01:25:51,325 --> 01:25:56,997
SO YES, I SORT OF IMPRINTED YOUR

2271
01:25:56,997 --> 01:25:59,533
SUGGESTION IN MY BRAIN, BECAUSE

2272
01:25:59,533 --> 01:26:02,036
I THINK IT WILL BE INCREDIBLY

2273
01:26:02,036 --> 01:26:04,038
VALUABLE AND IT WILL HELP PEOPLE

2274
01:26:04,038 --> 01:26:06,741
UNDERSTAND BETTER AND MAKE

2275
01:26:06,741 --> 01:26:08,275
DECISIONS ON HOW MUCH DRUGS THEY

2276
01:26:08,275 --> 01:26:09,176
CONSUME OR NOT.

2277
01:26:09,176 --> 01:26:10,811
WHICH IS WHAT THEY ARE DOING BUT

2278
01:26:10,811 --> 01:26:12,113
THEY'RE DOING BLINDLY, THEY

2279
01:26:12,113 --> 01:26:13,314
DON'T REALLY UNDERSTAND WHAT

2280
01:26:13,314 --> 01:26:15,282
COULD BE CONSEQUENTIAL.

2281
01:26:15,282 --> 01:26:19,320
TRAVIS?

2282
01:26:19,320 --> 01:26:20,588
>> THIS IS MY FAVORITE
PART OF

2283
01:26:20,588 --> 01:26:22,490
THE MEETING EVERY TIME.

2284
01:26:22,490 --> 01:26:23,257
THIS CONVERSATION IS ALWAYS SO

2285
01:26:23,257 --> 01:26:24,859
RICH.

2286
01:26:24,859 --> 01:26:26,527
I JUST -- I THOUGHT I WOULD

2287
01:26:26,527 --> 01:26:28,729
MENTION TWO PLACES WHERE I HEARD

2288
01:26:28,729 --> 01:26:31,565
MY WORLD INVOKED JUST IN CASE IT

2289
01:26:31,565 --> 01:26:34,301
COULD BE USEFUL IN THE FUTURE SO

2290
01:26:34,301 --> 01:26:36,270
YOU KNOW I COME FROM BIOETHICS

2291
01:26:36,270 --> 01:26:37,671
AND MEDICAL HUMANITIES AND TO

2292
01:26:37,671 --> 01:26:40,875
SOME EXTENT PHILOSOPHY, AND WE

2293
01:26:40,875 --> 01:26:43,477
FIND OURSELVES FEELING A BIT

2294
01:26:43,477 --> 01:26:45,679
LIKE WEIRDOS BECAUSE WE DON'T

2295
01:26:45,679 --> 01:26:47,314
ALWAYS DO THE EMPIRICAL OR

2296
01:26:47,314 --> 01:26:48,582
SCIENTIFIC WORK, BUT THERE ARE

2297
01:26:48,582 --> 01:26:50,418
TWO PLACES, ONE DURING YOUR

2298
01:26:50,418 --> 01:26:51,719
PRESENTATION, NORA, AND THEN ONE

2299
01:26:51,719 --> 01:26:54,021
DURING THIS CONVERSATION WHERE I

2300
01:26:54,021 --> 01:26:56,190
THOUGHT THAT'S BREAD AND BUTTER

2301
01:26:56,190 --> 01:26:58,592
BIOETHICS AND CONCEPTUAL WORK

2302
01:26:58,592 --> 01:26:59,693
THAT FEELS LIKE THERE'S A REAL

2303
01:26:59,693 --> 01:27:00,227
ROLE FOR.

2304
01:27:00,227 --> 01:27:01,862
SO ONE OF THEM WAS WHEN, NORA,

2305
01:27:01,862 --> 01:27:04,398
YOU BROUGHT UP THE QUESTION OF,

2306
01:27:04,398 --> 01:27:06,467
YOU KNOW, WHY DON'T WE EMPLOY

2307
01:27:06,467 --> 01:27:07,768
MORE HARM REDUCTION WHEN THE

2308
01:27:07,768 --> 01:27:09,970
EVIDENCE IS SO STRONG?

2309
01:27:09,970 --> 01:27:11,605
THERE'S A PURELY EMPIRICAL

2310
01:27:11,605 --> 01:27:13,140
VERSION OF THAT QUESTION WHICH

2311
01:27:13,140 --> 01:27:14,642
IS LIKE PEOPLE MAKE JUDGMENTS,

2312
01:27:14,642 --> 01:27:16,444
WHY DO THEY DO IT, WE CAN GO ASK

2313
01:27:16,444 --> 01:27:17,745
THEM AND FIND OUT THE ANSWER.

2314
01:27:17,745 --> 01:27:19,914
BUT THERE'S ALSO A SPACE THAT

2315
01:27:19,914 --> 01:27:22,116
I'VE WORKED IN AND SOME OF MY

2316
01:27:22,116 --> 01:27:23,217
COLLEAGUES HAVE WORKED IN, WHICH

2317
01:27:23,217 --> 01:27:25,052
IS PEOPLE ARE MAKING MORAL

2318
01:27:25,052 --> 01:27:26,287
JUDGMENTS HERE.

2319
01:27:26,287 --> 01:27:28,889
THEY'RE LARGELY SAYING THAT

2320
01:27:28,889 --> 01:27:31,959
SOMETHING IS WRONG ABOUT THIS

2321
01:27:31,959 --> 01:27:32,927
PRACTICE, IT'S SOMETHING MORALLY

2322
01:27:32,927 --> 01:27:35,563
WRONG, SO WRAPPED UP IN THE

2323
01:27:35,563 --> 01:27:37,264
STIGMA IS THEIR JUDGMENTS AND

2324
01:27:37,264 --> 01:27:38,966
THEIR CHOICE.

2325
01:27:38,966 --> 01:27:41,268
AND SO THERE'S REAL IMPORTANT

2326
01:27:41,268 --> 01:27:45,639
UNTANGLING TO BE DONE ABOUT

2327
01:27:45,639 --> 01:27:46,807
WHAT'S REASONABLE TO SAY AND

2328
01:27:46,807 --> 01:27:47,842
WHAT'S NOT, SO THAT WE CAN HAVE

2329
01:27:47,842 --> 01:27:50,044
A BETTER INFORMED CONVERSATION.

2330
01:27:50,044 --> 01:27:50,911
BECAUSE ONE OF THE THINGS THAT I

2331
01:27:50,911 --> 01:27:53,881
THINK IS HAPPENING IN YOUR

2332
01:27:53,881 --> 01:27:58,285
TRADEMARK TRAVIS EDITORIALIZING,

2333
01:27:58,285 --> 01:28:01,422
BUT WHAT HAPPENS IS, PEOPLE HAVE

2334
01:28:01,422 --> 01:28:02,623
AN IMPLICIT MORAL PHILOSOPHY

2335
01:28:02,623 --> 01:28:03,824
THAT MAKES A TON OF SENSE IN A

2336
01:28:03,824 --> 01:28:05,292
LOT OF PLACE, WHICH INVOLVES

2337
01:28:05,292 --> 01:28:06,560
THINGS LIKE DESSERTS, LIKE

2338
01:28:06,560 --> 01:28:07,995
PEOPLE DESERVE CERTAIN THINGS.

2339
01:28:07,995 --> 01:28:09,096
MOST PEOPLE IN THIS ROOM BELIEVE

2340
01:28:09,096 --> 01:28:10,631
THAT SOME PEOPLE DESERVE CERTAIN

2341
01:28:10,631 --> 01:28:11,765
THINGS, GOOD AND BAD, BASED ON

2342
01:28:11,765 --> 01:28:12,800
WHAT YOU'VE DONE IN THE PAST.

2343
01:28:12,800 --> 01:28:14,568
BUT THEN THEY APPLY TO A CONTEXT

2344
01:28:14,568 --> 01:28:16,971
LIKE DRUG USE, AND THEY GET

2345
01:28:16,971 --> 01:28:20,040
SOME, LIKE, MISFIRING JUDGMENTS.

2346
01:28:20,040 --> 01:28:21,408
AND THAT SORT OF CONCEPTUAL WORK

2347
01:28:21,408 --> 01:28:22,443
CAN BE REALLY IMPORTANT WHEN WE

2348
01:28:22,443 --> 01:28:24,278
TRY TO FIGURE OUT HOW DO YOU

2349
01:28:24,278 --> 01:28:25,513
MOVE FORWARD ENGAGING THIS

2350
01:28:25,513 --> 01:28:26,146
POPULATION.

2351
01:28:26,146 --> 01:28:28,015
BECAUSE DATA IS NOT MOVING THE

2352
01:28:28,015 --> 01:28:28,782
CONVERSATION FORWARD.

2353
01:28:28,782 --> 01:28:29,950
WE JUST KEEP HITTING PEOPLE OVER

2354
01:28:29,950 --> 01:28:31,185
THE HEAD WITH DATA SHOWING THAT,

2355
01:28:31,185 --> 01:28:33,287
YOU KNOW, HARM REDUCTION WORKS,

2356
01:28:33,287 --> 01:28:34,154
AND PEOPLE DON'T CHANGE THEIR

2357
01:28:34,154 --> 01:28:36,223
MINDS.

2358
01:28:36,223 --> 01:28:37,992
SO SOAP BOX, SORRY, BUT THAT'S

2359
01:28:37,992 --> 01:28:41,695
ONE PLACE WHERE I THINK

2360
01:28:41,695 --> 01:28:42,663
BIOETHICS AND HEALTH POLICY CAN

2361
01:28:42,663 --> 01:28:43,330
BE HELPFUL.

2362
01:28:43,330 --> 01:28:44,331
THE OTHER WAS THIS CONVERSATION

2363
01:28:44,331 --> 01:28:45,533
THAT WAS JUST HAPPENING ABOUT

2364
01:28:45,533 --> 01:28:47,401
HARM, RISK, RISK CATEGORIES AND

2365
01:28:47,401 --> 01:28:52,940
THRESHOLD.

2366
01:28:52,940 --> 01:28:54,642
YOU KNOW, THERE ARE MANY UNSAFE

2367
01:28:54,642 --> 01:28:59,647
LEVELS OF CHEESE CONSUMPTION,

2368
01:28:59,647 --> 01:29:01,315
AND WE WOULDN'T PUT IT INTO A

2369
01:29:01,315 --> 01:29:02,950
CATEGORY THAT DOCTORS ASK ABOUT

2370
01:29:02,950 --> 01:29:05,152
AND THAT KIND OF THREATENS

2371
01:29:05,152 --> 01:29:08,622
RAISING STIG MA STIGMA, I THINKN

2372
01:29:08,622 --> 01:29:10,257
CHEESE CONSUMPTION IS PROBABLY

2373
01:29:10,257 --> 01:29:12,459
UNSAFE TO SOME DEGREE, BUT ALSO

2374
01:29:12,459 --> 01:29:13,794
BICYCLING AND SKIING AND ALL

2375
01:29:13,794 --> 01:29:14,662
THESE OTHER SORTS OF THINGS.

2376
01:29:14,662 --> 01:29:16,730
SO THAT'S JUST A GOOFY WAY OF

2377
01:29:16,730 --> 01:29:19,266
SAYING RISK, SAFETY, HARM, AND

2378
01:29:19,266 --> 01:29:20,467
ESPECIALLY TRYING TO ESTABLISH A

2379
01:29:20,467 --> 01:29:21,769
THRESHOLD OR A THRESHOLD IS

2380
01:29:21,769 --> 01:29:23,571
SOMETHING LIKE WE OUGHT NOT TO

2381
01:29:23,571 --> 01:29:26,073
GO PAST THIS.

2382
01:29:26,073 --> 01:29:27,608
THAT OUGHT IS NORMATIVE, RIGHT?

2383
01:29:27,608 --> 01:29:29,677
IT'S OUR JUDGMENT ABOUT WHAT'S

2384
01:29:29,677 --> 01:29:30,778
RATIONAL, WHAT'S GOOD FOR YOU,

2385
01:29:30,778 --> 01:29:32,079
WHAT'S RIGHT TO DO, WHAT'S RIGHT

2386
01:29:32,079 --> 01:29:33,948
FOR THE MEDICAL SYSTEM TO SORT

2387
01:29:33,948 --> 01:29:36,016
OF IMPOSE ON.

2388
01:29:36,016 --> 01:29:39,186
SO THAT'S JUST -- YOU KNOW,

2389
01:29:39,186 --> 01:29:42,923
YOU'VE GOT ME HERE, I SAW SOME

2390
01:29:42,923 --> 01:29:44,024
NAILS, THOUGHT I'D OFFER THEM UP

2391
01:29:44,024 --> 01:29:44,792
FOR WHAT IT'S WORTH.

2392
01:29:44,792 --> 01:29:46,860
>> NO, TRAVIS, THANKS A
LOT AND

2393
01:29:46,860 --> 01:29:48,162
I'M GLAD THAT YOU BROUGHT IT UP.

2394
01:29:48,162 --> 01:29:49,463
WHAT I WOULD SORT OF SAY IS

2395
01:29:49,463 --> 01:29:52,533
BRINGING IN FORWARD THAT CHARLES

2396
01:29:52,533 --> 01:29:53,867
BASICALLY SUGGESTION AND -- I

2397
01:29:53,867 --> 01:29:55,736
WOULD DO A CHOLESTEROL TEST AND

2398
01:29:55,736 --> 01:29:57,905
SEE IF YOUR CHEESE IS HARMFUL OR

2399
01:29:57,905 --> 01:29:59,139
NOT TO YOU.

2400
01:29:59,139 --> 01:30:00,674
AND IF YOUR CHOLESTEROL TEST IS

2401
01:30:00,674 --> 01:30:01,875
GOOD, I WOULDN'T WORRY ABOUT IT.

2402
01:30:01,875 --> 01:30:03,510
I MEAN, AND I THINK THAT THAT'S

2403
01:30:03,510 --> 01:30:05,679
EXACTLY IN TERMS OF THE POINT,

2404
01:30:05,679 --> 01:30:07,181
AND THEN YOU CAN MAKE THE

2405
01:30:07,181 --> 01:30:08,349
DECISION AND YOU HAVE THAT DATA,

2406
01:30:08,349 --> 01:30:09,316
YOU CAN MAKE IT.

2407
01:30:09,316 --> 01:30:12,152
SO I DO VERY MUCH RESONATE AND

2408
01:30:12,152 --> 01:30:16,790
I'M VERY AWARE HOW STRONG ARE

2409
01:30:16,790 --> 01:30:17,858
THE MORAL JUDGMENTS OF WHAT

2410
01:30:17,858 --> 01:30:19,293
PEOPLE DESERVE BASED ON THEIR

2411
01:30:19,293 --> 01:30:20,060
BEHAVIOR.

2412
01:30:20,060 --> 01:30:21,261
BUT THE WAY THAT I PHRASE IT

2413
01:30:21,261 --> 01:30:26,100
MYSELF, IS THERE DATA, AGAIN

2414
01:30:26,100 --> 01:30:28,035
THINK WE NEED TO CHALLENGE

2415
01:30:28,035 --> 01:30:28,936
OURSELVES THAT WE USE TO CHANGE

2416
01:30:28,936 --> 01:30:29,570
A POLICY.

2417
01:30:29,570 --> 01:30:31,238
I ALWAYS SAY, BECAUSE IF IT'S SO

2418
01:30:31,238 --> 01:30:32,206
CONSEQUENTIAL THAT THE POLICY

2419
01:30:32,206 --> 01:30:33,540
MAKERS CANNOT IGNORE IT, THEN

2420
01:30:33,540 --> 01:30:34,842
YOU HAVE A POLICY, AND ONCE YOU

2421
01:30:34,842 --> 01:30:38,579
HAVE A POLICY, THAT ACTUALLY CAN

2422
01:30:38,579 --> 01:30:40,114
COMPENSATE EVEN FOR PEOPLE THAT

2423
01:30:40,114 --> 01:30:41,649
ARE DISCRIMINATORY AND

2424
01:30:41,649 --> 01:30:42,816
STIGMATIZED AND IF THERE'S

2425
01:30:42,816 --> 01:30:43,617
POLICIES THAT REQUIRE THAT YOU

2426
01:30:43,617 --> 01:30:48,656
DO THIS OR THE OTHER.

2427
01:30:48,656 --> 01:30:48,956
, THEN

2428
01:30:48,956 --> 01:30:49,757
THAT'S SORT OF THE WAY THAT I

2429
01:30:49,757 --> 01:30:50,190
VIEW IT.

2430
01:30:50,190 --> 01:30:52,026
BUT WE NEED TO BE VERY AWARE,

2431
01:30:52,026 --> 01:30:53,694
OBVIOUSLY, THAT A LOT OF THAT

2432
01:30:53,694 --> 01:30:55,796
DIFFICULTY WITH SYRINGE EXCHANGE

2433
01:30:55,796 --> 01:30:57,398
PROGRAMS, OF CLOSING THEM, IS

2434
01:30:57,398 --> 01:30:58,966
BASICALLY PREJUDICE, AND TO A

2435
01:30:58,966 --> 01:31:00,401
CERTAIN EXTENT PERHAPS EVEN WHAT

2436
01:31:00,401 --> 01:31:01,602
YOU'RE SAYING, PEOPLE THINKING,

2437
01:31:01,602 --> 01:31:03,570
WELL, THEY GET WHAT THEY

2438
01:31:03,570 --> 01:31:07,074
DESERVE, SO IT'S -- AND THAT

2439
01:31:07,074 --> 01:31:08,609
PERSPECTIVE SOMETIMES

2440
01:31:08,609 --> 01:31:11,245
UNFORTUNATELY IS DRIVEN VERY

2441
01:31:11,245 --> 01:31:12,579
MUCH BY LACK OF UNDERSTANDING,

2442
01:31:12,579 --> 01:31:14,648
SO I THINK THAT'S THE OTHER

2443
01:31:14,648 --> 01:31:17,751
ASPECT, WE'RE TRYING TO

2444
01:31:17,751 --> 01:31:18,719
DISSEMINATE KNOWLEDGE, SO

2445
01:31:18,719 --> 01:31:20,821
HOPEFULLY WE CAN CHANGE THOSE

2446
01:31:20,821 --> 01:31:23,657
STIGMATIZING PERCEPTIONS.

2447
01:31:23,657 --> 01:31:24,858
SHELLEY, YOU HAD YOUR HAND

2448
01:31:24,858 --> 01:31:26,193
RAISED.

2449
01:31:26,193 --> 01:31:28,162
>> THANK YOU SO MUCH.

2450
01:31:28,162 --> 01:31:29,329
AND I AGREE WITH TRAVIS, THIS IS

2451
01:31:29,329 --> 01:31:30,564
ONE OF THE GREAT PARTS OF THIS

2452
01:31:30,564 --> 01:31:33,634
MEETING, AND THANKS AGAIN FOR A

2453
01:31:33,634 --> 01:31:34,201
COMPREHENSIVE PRESENTATION,

2454
01:31:34,201 --> 01:31:34,401
NORA.

2455
01:31:34,401 --> 01:31:36,170
YOU KNOW, I'VE BEEN FINDING

2456
01:31:36,170 --> 01:31:37,705
MYSELF FOR PART OF THIS

2457
01:31:37,705 --> 01:31:40,641
DISCUSSION JUST STUCK BACK ON

2458
01:31:40,641 --> 01:31:43,510
THE ADOLESCENT SUBSTANCE USE

2459
01:31:43,510 --> 01:31:45,145
DISORDER PAST YEAR DATA AND THE

2460
01:31:45,145 --> 01:31:47,881
MINIMAL NUMBERS OF PEOPLE

2461
01:31:47,881 --> 01:31:50,317
ACCESSING ANY TYPE OF TREATMENT.

2462
01:31:50,317 --> 01:31:54,254
AND THE INCREDIBLE NEED

2463
01:31:54,254 --> 01:31:55,656
TREATMENT GAP IN THE UNITED

2464
01:31:55,656 --> 01:31:56,590
STATES, AND OF COURSE IT'S FOR

2465
01:31:56,590 --> 01:31:57,891
ALL PEOPLE WITH SUBSTANCE USE

2466
01:31:57,891 --> 01:31:59,393
DISORDERS, BUT THIS ADOLESCENT

2467
01:31:59,393 --> 01:32:00,828
GROUP, IT'S EVEN LOWER THAN WHAT

2468
01:32:00,828 --> 01:32:02,262
WE EXPECT IN THE ADULTS, AND I

2469
01:32:02,262 --> 01:32:04,331
JUST KEEP GOING OVER THOSE

2470
01:32:04,331 --> 01:32:05,632
STATISTICS AND I'VE BEEN TRYING

2471
01:32:05,632 --> 01:32:07,868
TO TURN IT INTO SOME RESEARCH

2472
01:32:07,868 --> 01:32:11,572
QUESTIONS THAT WE MIGHT BE ABLE

2473
01:32:11,572 --> 01:32:13,307
TO, YOU KNOW, WORK ON, AND I

2474
01:32:13,307 --> 01:32:16,810
FIND MYSELF THINKING ABOUT THAT

2475
01:32:16,810 --> 01:32:18,779
AREA AS BEING KIND OF RIPE FOR

2476
01:32:18,779 --> 01:32:21,315
THINGS LIKE, YOU KNOW, MIXED

2477
01:32:21,315 --> 01:32:23,517
METHOD STUDIES WHERE WE MIGHT BE

2478
01:32:23,517 --> 01:32:25,052
DOING SOME COMMUNITY-BASED

2479
01:32:25,052 --> 01:32:29,189
PARTICIPATORY RESEARCH, TO GO

2480
01:32:29,189 --> 01:32:30,057
INTO THE COMMUNITIES AND FIND

2481
01:32:30,057 --> 01:32:31,091
OUT WHAT THEIR NEEDS ARE AND

2482
01:32:31,091 --> 01:32:32,726
WHAT THE BARRIERS AND OBSTACLES

2483
01:32:32,726 --> 01:32:35,829
ARE, WHICH COULD BE INCLUSIVE OF

2484
01:32:35,829 --> 01:32:37,030
CO-OCCURRING OTHER PSYCHIATRIC

2485
01:32:37,030 --> 01:32:37,998
DISORDERS AMONGST THE ADD LE

2486
01:32:37,998 --> 01:32:39,333
SENT POPULATION, WHERE IT

2487
01:32:39,333 --> 01:32:40,634
BECOMES VERY HARD TO ACCESS ANY

2488
01:32:40,634 --> 01:32:44,938
KIND OF CARE FOR ADOLESCENTS.

2489
01:32:44,938 --> 01:32:46,907
IT COULD ALSO ACTUALLY SURFACE

2490
01:32:46,907 --> 01:32:48,642
EVEN MORE THE LACK OF PROVIDERS,

2491
01:32:48,642 --> 01:32:50,744
AND IT DOES SEEM TO ME THAT WHEN

2492
01:32:50,744 --> 01:32:52,279
WE COLLECT DATA LIKE THAT, BY

2493
01:32:52,279 --> 01:32:54,715
GOING INTO THE COMMUNITY AND

2494
01:32:54,715 --> 01:32:57,651
ASKING, AND THEN ACTUALLY LOOK

2495
01:32:57,651 --> 01:32:59,653
AT WHAT EXISTS AND WHAT PEOPLE

2496
01:32:59,653 --> 01:33:02,589
TELL YOU ARE THE BARRIERS, THAT

2497
01:33:02,589 --> 01:33:05,993
OFTEN CAN BE SURFACED TOWARD

2498
01:33:05,993 --> 01:33:06,660
CHANGING POLICY.

2499
01:33:06,660 --> 01:33:08,495
BECAUSE RIGHT NOW WE JUST REALLY

2500
01:33:08,495 --> 01:33:13,200
DON'T HAVE ANY POLICY TO TRY TO

2501
01:33:13,200 --> 01:33:16,069
PROVIDE BETTER ACCESS FOR, YOU

2502
01:33:16,069 --> 01:33:18,372
KNOW, KIDS AND THEIR PARENTS AND

2503
01:33:18,372 --> 01:33:19,473
FAMILIES, AND THE OTHER THING

2504
01:33:19,473 --> 01:33:23,977
ABOUT THAT ALSO IS THAT WE'RE

2505
01:33:23,977 --> 01:33:25,512
HAVING A REALLY HARD TIME WITH

2506
01:33:25,512 --> 01:33:29,316
THE WORKFORCE SITUATION.

2507
01:33:29,316 --> 01:33:30,651
SO SOMETIMES WHEN YOU CAN GET IN

2508
01:33:30,651 --> 01:33:32,119
AND ACTUALLY ESTABLISH THOSE

2509
01:33:32,119 --> 01:33:36,490
DATA, IT CAN HELP US WITH THE

2510
01:33:36,490 --> 01:33:39,893
POLICY QUESTIONS THAT COME UP

2511
01:33:39,893 --> 01:33:43,931
ABOUT THE WORKFORCE STRATEGY,

2512
01:33:43,931 --> 01:33:50,604
LIKE THERE ARE VERY, VERY FEW --

2513
01:33:50,604 --> 01:33:51,538
ALMOST NONE OF THEM ARE

2514
01:33:51,538 --> 01:33:56,410
ADDICTION TRAINED, IT'S LIKE 30,

2515
01:33:56,410 --> 01:33:57,845
MAYBE IT'S 40, I DON'T KNOW, BUT

2516
01:33:57,845 --> 01:33:59,413
THAT'S FOR THE WHOLE U.S., AND

2517
01:33:59,413 --> 01:34:00,414
I'M JUST TALKING ABOUT

2518
01:34:00,414 --> 01:34:01,715
PSYCHIATRY ITSELF BECAUSE THOSE

2519
01:34:01,715 --> 01:34:05,352
ARE THE STATISTICS I KNOW THE

2520
01:34:05,352 --> 01:34:09,423
BEST, BUT THERE'S JUST A HUGE

2521
01:34:09,423 --> 01:34:10,757
GAP NEED SO THAT COULD BE ONE

2522
01:34:10,757 --> 01:34:11,725
AREA I WAS THINKING ABOUT FOR

2523
01:34:11,725 --> 01:34:12,392
THAT.

2524
01:34:12,392 --> 01:34:15,229
A SECOND THING THAT THIS TOUCHES

2525
01:34:15,229 --> 01:34:16,897
ON BUT WASN'T A MAIN FOCUS BUT I

2526
01:34:16,897 --> 01:34:18,966
JUST WANTED TO MENTION TODAY IS

2527
01:34:18,966 --> 01:34:20,934
JUST, AGAIN, WITH THE WORKFORCE

2528
01:34:20,934 --> 01:34:25,439
SITUATION IN TERMS OF THE NEW

2529
01:34:25,439 --> 01:34:26,974
GENERATION OF ADDICTION

2530
01:34:26,974 --> 01:34:29,376
RESEARCHERS, ESPECIALLY

2531
01:34:29,376 --> 01:34:30,377
CLINICIAN-SCIENTISTS AND

2532
01:34:30,377 --> 01:34:31,445
ESPECIALLY PHYSICIAN SCIENTISTS,

2533
01:34:31,445 --> 01:34:32,779
WE'RE REALLY SEEING LIKE A

2534
01:34:32,779 --> 01:34:36,283
COMPLETE PLUMMETING OF THAT, AND

2535
01:34:36,283 --> 01:34:38,252
A GROUP OF US HAVE BEEN TRYING

2536
01:34:38,252 --> 01:34:40,153
TO FIGURE OUT, WHAT KINDS OF

2537
01:34:40,153 --> 01:34:41,788
INITIATIVES COULD HAPPEN THAT

2538
01:34:41,788 --> 01:34:44,024
MIGHT HELP MOVE PEOPLE WHO ARE

2539
01:34:44,024 --> 01:34:47,561
SORT OF IN TRAINING WHO WANT TO

2540
01:34:47,561 --> 01:34:49,062
DO THIS BUT FEEL LIKE THAT

2541
01:34:49,062 --> 01:34:51,565
TRANSITION FROM FINISHING YOUR

2542
01:34:51,565 --> 01:34:56,737
TRAINING, LET'S SAY PSYCHOL PSYY

2543
01:34:56,737 --> 01:34:59,239
RESIDENCY TO LIKE AN EARLY

2544
01:34:59,239 --> 01:35:00,140
INVESTIGATOR MODE IS ALMOST

2545
01:35:00,140 --> 01:35:01,475
IMPOSSIBLE FOR MANY AND THEY GET

2546
01:35:01,475 --> 01:35:02,542
BASICALLY MOVED OFF INTO

2547
01:35:02,542 --> 01:35:05,178
CLINICAL PRACTICE OR INTO OTHER

2548
01:35:05,178 --> 01:35:06,146
FORMS OF THE PRIVATE SECTOR.

2549
01:35:06,146 --> 01:35:07,681
I WAS JUST WONDERING ABOUT THE

2550
01:35:07,681 --> 01:35:11,184
IDEA OF TARGETED SUPPLEMENTS FOR

2551
01:35:11,184 --> 01:35:14,254
PIs WITH GRANTS THAT WOULD

2552
01:35:14,254 --> 01:35:18,759
ACTUALLY ENCOURAGE BRINGING IN

2553
01:35:18,759 --> 01:35:20,027
CERTAIN YOUNG INVESTIGATORS,

2554
01:35:20,027 --> 01:35:21,094
JUNIOR INVESTIGATORS WITH

2555
01:35:21,094 --> 01:35:24,364
CERTAIN PROFILES, AND

2556
01:35:24,364 --> 01:35:25,799
PARTICULARLY IN THIS INSTANCE

2557
01:35:25,799 --> 01:35:26,466
THINKING ABOUT PHYSICIAN

2558
01:35:26,466 --> 01:35:28,302
SCIENTISTS WHERE THERE'S LIKE

2559
01:35:28,302 --> 01:35:29,836
LITERALLY A PLUMMETING FALLOFF,

2560
01:35:29,836 --> 01:35:31,471
I'VE BEEN TALKING TO A LOT OF

2561
01:35:31,471 --> 01:35:33,740
PEOPLE WITH R25s RIGHT NOW TO

2562
01:35:33,740 --> 01:35:34,908
TRAIN PHYSICIAN SCIENTISTS IN

2563
01:35:34,908 --> 01:35:36,443
ADDICTION AND THEY JUST ARE

2564
01:35:36,443 --> 01:35:38,445
FALLING RIGHT OFF RIGHT AFTER.

2565
01:35:38,445 --> 01:35:40,213
SO AS A SECOND THING AND THEN

2566
01:35:40,213 --> 01:35:42,816
THE THIRD THING JUST TO

2567
01:35:42,816 --> 01:35:45,452
CHARLES' -- THE WHOLE IDEA OF

2568
01:35:45,452 --> 01:35:48,655
THRESHOLDS AND UNFORTUNATELY I

2569
01:35:48,655 --> 01:35:50,190
THINK A LOT OF PEOPLE KNOW,

2570
01:35:50,190 --> 01:35:51,591
PHYSICIANS ARE VERY POORLY

2571
01:35:51,591 --> 01:35:55,362
TRAINED IN ADDICTION, ALL OF IT.

2572
01:35:55,362 --> 01:35:56,363
ALCOHOL, MAYBE TOBACCO, THEY'RE

2573
01:35:56,363 --> 01:35:59,733
PRETTY WELL TRAINED, BUT NOT

2574
01:35:59,733 --> 01:36:01,234
EVEN THERE IN TERMS OF OFFERING,

2575
01:36:01,234 --> 01:36:02,602
YOU KNOW, THEY KNOW IT'S BAD FOR

2576
01:36:02,602 --> 01:36:05,138
YOU, BUT THEY ALMOST NEVER

2577
01:36:05,138 --> 01:36:08,008
OFFER, YOU KNOW, NICOTINE

2578
01:36:08,008 --> 01:36:09,376
REPLACEMENT THERAPIES OR ANY OF

2579
01:36:09,376 --> 01:36:11,411
THE OTHER KINDS OF TREATMENTS.

2580
01:36:11,411 --> 01:36:14,481
THEY'RE NOTORIOUSLY BAD AT THIS,

2581
01:36:14,481 --> 01:36:21,321
AND YOU KNOW, I THINK THAT ONE

2582
01:36:21,321 --> 01:36:23,256
OF THE CHALLENGES WE HAVE IS HOW

2583
01:36:23,256 --> 01:36:25,559
DO WE PRODUCE, TO TRAVIS' POINT,

2584
01:36:25,559 --> 01:36:26,793
A GOOD WAY FOR PEOPLE TO TAKE

2585
01:36:26,793 --> 01:36:29,830
THE DATA, AND THEN HELP TRANSFER

2586
01:36:29,830 --> 01:36:33,233
THE DATA INTO PEOPLE'S SPECIFIC

2587
01:36:33,233 --> 01:36:34,568
RISK PORTFOLIOS, YOU KNOW?

2588
01:36:34,568 --> 01:36:38,405
BECAUSE FOR EVERY PERSON, YOU

2589
01:36:38,405 --> 01:36:41,775
KNOW, THEIR RISK PORTFOLIO IS

2590
01:36:41,775 --> 01:36:43,543
DIFFERENT BASED ON THEIR FAMILY

2591
01:36:43,543 --> 01:36:44,811
HISTORY, THEIR GENETICS AND

2592
01:36:44,811 --> 01:36:45,746
THEIR SOCIAL ENVIRONMENTAL

2593
01:36:45,746 --> 01:36:46,179
HISTORY.

2594
01:36:46,179 --> 01:36:47,614
SO LIKE I'LL JUST GIVE YOU ONE

2595
01:36:47,614 --> 01:36:50,550
BIG EXAMPLE.

2596
01:36:50,550 --> 01:36:52,019
FOR WOMEN WHO HAVE A FAMILY

2597
01:36:52,019 --> 01:36:53,086
HISTORY OF BREAST CANCER, BASED

2598
01:36:53,086 --> 01:36:56,289
ON THE DATA RIGHT NOW, IF YOU'RE

2599
01:36:56,289 --> 01:36:57,424
A PHYSICIAN, YOU'RE SEEING A

2600
01:36:57,424 --> 01:36:59,159
WOMAN AND YOU WANT TO TALK TO

2601
01:36:59,159 --> 01:37:01,028
HER ABOUT MODIFIABLE RISK

2602
01:37:01,028 --> 01:37:02,229
FACTORS, DECREASING OR

2603
01:37:02,229 --> 01:37:03,196
ELIMINATING ALCOHOL FROM THE

2604
01:37:03,196 --> 01:37:05,565
DIET ACTUALLY IS ONE MODIFIABLE

2605
01:37:05,565 --> 01:37:07,501
RISK FACTOR, ALONG WITH, YOU

2606
01:37:07,501 --> 01:37:08,935
KNOW, EXERCISE AND DIET.

2607
01:37:08,935 --> 01:37:10,537
SO IT'S VERY RARE, THOUGH, FOR

2608
01:37:10,537 --> 01:37:12,239
PHYSICIANS TO EVER HAVE THOSE

2609
01:37:12,239 --> 01:37:13,106
CONVERSATIONS WITH WOMEN.

2610
01:37:13,106 --> 01:37:14,574
I KNOW BECAUSE I TALK TO A LOT

2611
01:37:14,574 --> 01:37:16,877
OF WOMEN THAT HAVE THESE

2612
01:37:16,877 --> 01:37:18,078
CONVERSATIONS, SO I THINK TAKING

2613
01:37:18,078 --> 01:37:19,613
DATA AND TRYING TO FIGURE OUT

2614
01:37:19,613 --> 01:37:22,049
HOW TO HELP CLINICIAN,

2615
01:37:22,049 --> 01:37:24,351
ESPECIALLY PHYSICIANS, FIGURE

2616
01:37:24,351 --> 01:37:27,621
OUT HOW TO TALK TO PEOPLE ABOUT

2617
01:37:27,621 --> 01:37:30,590
THEIR RISK PORTFOLIO, YOU KNOW,

2618
01:37:30,590 --> 01:37:32,125
RATHER THAN MAYBE IT'S NOT

2619
01:37:32,125 --> 01:37:33,860
ABSOLUTE THRESHOLDS, IT'S MORE

2620
01:37:33,860 --> 01:37:35,228
LIKE LET'S TALK ABOUT WHAT YOUR

2621
01:37:35,228 --> 01:37:36,730
RISKS ARE, YOUR INDIVIDUAL

2622
01:37:36,730 --> 01:37:38,165
RISKS, YOUR PERSONAL RISKS, YOUR

2623
01:37:38,165 --> 01:37:40,700
FAMILY RISKS, AND THEN LET'S

2624
01:37:40,700 --> 01:37:42,502
TALK ABOUT EVERYTHING THAT'S

2625
01:37:42,502 --> 01:37:44,004
MODIFIABLE HERE, WHICH INCLUDES

2626
01:37:44,004 --> 01:37:45,439
DIET, EXERCISE AND YOUR USE OF

2627
01:37:45,439 --> 01:37:51,278
ALL SUBSTANCES, ALL OF THEM.

2628
01:37:51,278 --> 01:37:52,612
BUT THAT'S NOT THE TRAJECTORY

2629
01:37:52,612 --> 01:37:54,181
THAT WE'RE ON RIGHT NOW.

2630
01:37:54,181 --> 01:37:55,582
SO I DON'T KNOW, MAYBE THERE'S

2631
01:37:55,582 --> 01:37:57,684
ALSO SOME DATA QUESTIONS AND

2632
01:37:57,684 --> 01:37:59,986
SOME, YOU KNOW, RESEARCH

2633
01:37:59,986 --> 01:38:02,422
QUESTIONS THERE LIKE YOU COULD

2634
01:38:02,422 --> 01:38:05,592
RUN SOME IMPLEMENTATION SCIENCE

2635
01:38:05,592 --> 01:38:09,429
TYPE OF RESEARCH WHERE YOU'RE

2636
01:38:09,429 --> 01:38:11,398
JUST DOING LIKE A PRAGMATIC

2637
01:38:11,398 --> 01:38:13,400
TRIAL OF, LIKE, SAME AS USUAL

2638
01:38:13,400 --> 01:38:16,103
VERSUS THIS TYPE OF COUNSELING,

2639
01:38:16,103 --> 01:38:17,904
YOU KNOW, IN PRIMARY CARE

2640
01:38:17,904 --> 01:38:18,138
OFFICES.

2641
01:38:18,138 --> 01:38:19,573
IT'S JUST ANOTHER THOUGHT ABOUT

2642
01:38:19,573 --> 01:38:20,874
THIS, BECAUSE I THINK WE'RE

2643
01:38:20,874 --> 01:38:23,844
PRETTY BAD AT THIS ACTUALLY FOR

2644
01:38:23,844 --> 01:38:24,478
PATIENTS.

2645
01:38:24,478 --> 01:38:26,179
AND THAT INCLUDES, YOU KNOW,

2646
01:38:26,179 --> 01:38:26,947
YOUNG PEOPLE.

2647
01:38:26,947 --> 01:38:29,349
NOT JUST THE ADOLESCENCE, BUT

2648
01:38:29,349 --> 01:38:30,851
THAT TRANSITIONAL-AGE GROUP

2649
01:38:30,851 --> 01:38:32,119
WHERE WE DON'T REALLY TALK TO

2650
01:38:32,119 --> 01:38:33,420
THEM ABOUT ANY OF THIS STUFF

2651
01:38:33,420 --> 01:38:34,754
REALLY VERY WELL EITHER, YOU

2652
01:38:34,754 --> 01:38:37,157
KNOW, AND TO TRAVIS' POINT, IT

2653
01:38:37,157 --> 01:38:40,127
OFTEN SOUNDS TO PEOPLE LIKE IT'S

2654
01:38:40,127 --> 01:38:42,229
LIKE A STIGMATIZING CONVERSATION

2655
01:38:42,229 --> 01:38:45,065
AS OPPOSED TO A HELPFUL

2656
01:38:45,065 --> 01:38:45,966
CONVERSATION, LIKE LET'S TALK

2657
01:38:45,966 --> 01:38:47,267
ABOUT YOUR RISKS AND FIGURE OUT

2658
01:38:47,267 --> 01:38:48,401
WHAT MIGHT BE BEST FOR YOU AND

2659
01:38:48,401 --> 01:38:52,906
WHAT YOU WANT TO TRY.

2660
01:38:52,906 --> 01:38:55,609
SO THOSE ARE JUST A BUNCH OF --

2661
01:38:55,609 --> 01:38:57,277
>> NO, SHELLEY, THANKS A
LOT.

2662
01:38:57,277 --> 01:38:57,878
I TOOK NOTE.

2663
01:38:57,878 --> 01:38:59,579
I MEAN, YOU'RE PROPOSING SEVERAL

2664
01:38:59,579 --> 01:39:02,149
THINGS THAT I THINK COULD BE

2665
01:39:02,149 --> 01:39:03,483
VERY, VERY USEFUL.

2666
01:39:03,483 --> 01:39:06,653
THEY ARE DISTINCT, BUT IT ALSO

2667
01:39:06,653 --> 01:39:08,188
HIGHLIGHTS THAT IN TERMS OF

2668
01:39:08,188 --> 01:39:10,490
ADDRESSING THE CHALLENGES THAT

2669
01:39:10,490 --> 01:39:12,259
WE HAVE FOR TREATMENT OF

2670
01:39:12,259 --> 01:39:13,460
ADOLESCENTS, I MEAN, BECAUSE

2671
01:39:13,460 --> 01:39:15,562
AGAIN, THIS IS SUCH A GAP AREA

2672
01:39:15,562 --> 01:39:19,833
AND WE BASICALLY HAD TO SAY HOW

2673
01:39:19,833 --> 01:39:22,569
CAN WE HELP AND BRING IN SAMHSA,

2674
01:39:22,569 --> 01:39:23,770
BECAUSE IT'S A KEY PARTNER IN

2675
01:39:23,770 --> 01:39:26,773
TERMS OF TRAINING BUT ALSO IN

2676
01:39:26,773 --> 01:39:28,308
TERMS OF PUTTING SUPPORT AND

2677
01:39:28,308 --> 01:39:34,347
BRINGING IN NIMH, US, AS YOU SAR

2678
01:39:34,347 --> 01:39:37,184
TEENAGERS, IT'S CO-MORBID.

2679
01:39:37,184 --> 01:39:38,285
SO IMPLEMENTATION GUIDELINES,

2680
01:39:38,285 --> 01:39:40,954
THIS IS AN OPPORTUNITY FOR BIG

2681
01:39:40,954 --> 01:39:43,156
DATA, YOU HAD THE DATA, QUALITY

2682
01:39:43,156 --> 01:39:45,492
DATA, YOU CAN JUST SAY AYE TO

2683
01:39:45,492 --> 01:39:48,962
GENERATE TRAJECTORIES THAT --

2684
01:39:48,962 --> 01:39:49,396
RISK.

2685
01:39:49,396 --> 01:39:56,870
ALSO IN PRINCIPLE, CAN WE TRAIN

2686
01:39:56,870 --> 01:39:58,305
AI ON DATABASES AND GET OUR

2687
01:39:58,305 --> 01:40:02,475
HANDS ON DATABASES THAT HAVE

2688
01:40:02,475 --> 01:40:07,414
BEEN SYSTEMATICALLY FOR -- BUT

2689
01:40:07,414 --> 01:40:08,715
WE ARE WORKING ON THAT, SO

2690
01:40:08,715 --> 01:40:10,250
THANKS A LOT, SHELLEY, AND ALL

2691
01:40:10,250 --> 01:40:11,851
OF YOU FOR THESE VERY GOOD

2692
01:40:11,851 --> 01:40:13,486
SUGGESTIONS.

2693
01:40:13,486 --> 01:40:15,322
WE MAY CALL BACK ON YOU AS WE

2694
01:40:15,322 --> 01:40:19,159
FOLLOW UP ON THESE

2695
01:40:19,159 --> 01:40:19,526
RECOMMENDATIONS.

2696
01:40:19,526 --> 01:40:21,061
>> THIS IS THE PART OF THE
JOB I

2697
01:40:21,061 --> 01:40:22,796
HATE THE MOST, WE'RE ALREADY

2698
01:40:22,796 --> 01:40:25,198
ALMOST THROUGH OUR BREAK SO OUR

2699
01:40:25,198 --> 01:40:26,700
NEXT TALK STARTS AT 2:30.

2700
01:40:26,700 --> 01:40:28,635
DO YOU WANT TO SKIP THE BREAK

2701
01:40:28,635 --> 01:40:30,270
AND START A FEW MINUTES LATE?

2702
01:40:30,270 --> 01:40:33,340
WE HAVE TWO MORE QUESTIONS.

2703
01:40:33,340 --> 01:40:34,674
>> I'LL LET COUNCIL
DECIDE.

2704
01:40:34,674 --> 01:40:40,247
I MEAN, I THINK THAT --

2705
01:40:40,247 --> 01:40:42,148
>> ANNA ROSE, IS IT A LONG

2706
01:40:42,148 --> 01:40:43,683
QUESTION OR A SHORT QUESTION?

2707
01:40:43,683 --> 01:40:47,120
>> JUST A REALLY SHORT
COMMENT

2708
01:40:47,120 --> 01:40:50,390
AND I GUESS ONE QUESTION.

2709
01:40:50,390 --> 01:40:52,826
THE SHORT COMMENT, REALLY SHORT,

2710
01:40:52,826 --> 01:40:54,127
IS THAT EARLIER IN OUR

2711
01:40:54,127 --> 01:40:55,028
DISCUSSION, WE WERE TALKING

2712
01:40:55,028 --> 01:40:56,863
ABOUT THE POLICY DRUG SITUATION,

2713
01:40:56,863 --> 01:40:59,165
WHICH OF COURSE IS SO VERY REAL

2714
01:40:59,165 --> 01:41:01,501
WITH FENTANYL UP AROUND OUR

2715
01:41:01,501 --> 01:41:03,036
ANKLES AND XYLAZINE COMING UP

2716
01:41:03,036 --> 01:41:05,138
AROUND OUR CALVES AND, YOU KNOW,

2717
01:41:05,138 --> 01:41:06,439
AT THIS POINT, IT SORT OF

2718
01:41:06,439 --> 01:41:09,409
REMINDS ME OF THE EARLY PART OF

2719
01:41:09,409 --> 01:41:10,944
NICOTINE PATCH RESEARCH WHEN

2720
01:41:10,944 --> 01:41:12,045
THEY MADE CARTOONS SHOWING THAT

2721
01:41:12,045 --> 01:41:15,382
YOU HAD PATCHES ON YOUR BODY FOR

2722
01:41:15,382 --> 01:41:17,117
EVERYTHING, FOR CHOCOLATE,

2723
01:41:17,117 --> 01:41:19,753
FOR -- THE POLYDRUG SITUATION IS

2724
01:41:19,753 --> 01:41:20,320
REALLY TRICKY.

2725
01:41:20,320 --> 01:41:22,622
SO I LOVE THE IDEA OF THE

2726
01:41:22,622 --> 01:41:24,924
SEQUESTERING MEDICATIONS.

2727
01:41:24,924 --> 01:41:26,393
HOW WILL WE, THOUGH, APPROACH

2728
01:41:26,393 --> 01:41:28,561
THESE VERY, VERY COMPLEX

2729
01:41:28,561 --> 01:41:30,096
PROFILES?

2730
01:41:30,096 --> 01:41:31,965
IT FEELS A LITTLE BIT IN THE

2731
01:41:31,965 --> 01:41:33,600
TRENCHES AS THOUGH WE'RE SORT OF

2732
01:41:33,600 --> 01:41:35,602
BATTLING THE WINDMILLS AND WHERE

2733
01:41:35,602 --> 01:41:36,803
WE'RE BASICALLY TRYING REALLY

2734
01:41:36,803 --> 01:41:38,672
HARD, BUT WE HAVE A NEW WRINKLE

2735
01:41:38,672 --> 01:41:40,106
THAT APPEARS, IT SEEMS LIKE

2736
01:41:40,106 --> 01:41:42,409
EVERY YEAR OR SO NOW, SO IT'S --

2737
01:41:42,409 --> 01:41:44,711
IT WOULD BE ENOUGH JUST TO HAVE

2738
01:41:44,711 --> 01:41:47,781
A VERY VEER OPIOID USE DISORDER,

2739
01:41:47,781 --> 01:41:49,115
BEFORE FENTANYL AND BEFORE

2740
01:41:49,115 --> 01:41:53,286
XYLAZINE AND BEFORE THE

2741
01:41:53,286 --> 01:41:54,120
NITAZINES AND BEFORE THE NEXT

2742
01:41:54,120 --> 01:41:54,421
TURN.

2743
01:41:54,421 --> 01:41:56,323
SO THERE'S A LOT OF SUNSHINE

2744
01:41:56,323 --> 01:41:57,691
TODAY HERE IN PHILADELPHIA, BUT

2745
01:41:57,691 --> 01:41:59,059
IT'S A REALLY TOUGH SITUATION,

2746
01:41:59,059 --> 01:42:01,895
AND I GUESS THAT POLYDRUG

2747
01:42:01,895 --> 01:42:03,530
PROFILE AND THAT SITUATION WHICH

2748
01:42:03,530 --> 01:42:05,632
IS NOT THE KIND OF THING THAT

2749
01:42:05,632 --> 01:42:07,200
REVIEWERS REALLY RESONATE TO

2750
01:42:07,200 --> 01:42:08,735
BECAUSE YOU WANT THE PURE STUDY,

2751
01:42:08,735 --> 01:42:10,337
YOU WANT THE PURE POPULATION,

2752
01:42:10,337 --> 01:42:12,272
YOU WANT THE ONE DISORDER IF YOU

2753
01:42:12,272 --> 01:42:13,907
CAN, WHEN, IN FACT, IT'S NOT THE

2754
01:42:13,907 --> 01:42:16,209
WAY OUR PATIENTS ARE REALLY

2755
01:42:16,209 --> 01:42:18,011
COMING PACKAGED AT THIS POINT.

2756
01:42:18,011 --> 01:42:20,080
FOR COCAINE, THE OVERDOSE

2757
01:42:20,080 --> 01:42:22,482
DEATHS, IT LIKE, WHAT, 70% OF

2758
01:42:22,482 --> 01:42:24,050
THEM HAVE FENTANYL IN THEM NOW.

2759
01:42:24,050 --> 01:42:25,585
IT'S JUST A CRAZY SITUATION.

2760
01:42:25,585 --> 01:42:26,820
THERE'S A HUGE INTERTWINING OF

2761
01:42:26,820 --> 01:42:30,724
THESE THINGS.

2762
01:42:30,724 --> 01:42:32,058
SO THAT'S JUST A QUICK COMMENT

2763
01:42:32,058 --> 01:42:33,026
IN TERMS OF I DON'T KNOW HOW WE

2764
01:42:33,026 --> 01:42:33,560
FIX THAT.

2765
01:42:33,560 --> 01:42:35,362
THE OTHER REALLY QUICK THING IS

2766
01:42:35,362 --> 01:42:36,796
THAT IN TERMS OF ATTRACTING

2767
01:42:36,796 --> 01:42:37,530
YOUNG PHYSICIAN, I DON'T KNOW,

2768
01:42:37,530 --> 01:42:40,166
WE'VE TALKED ABOUT IT BEFORE, IF

2769
01:42:40,166 --> 01:42:42,102
NIH IS THINKING ANY MORE ABOUT

2770
01:42:42,102 --> 01:42:45,171
JUST INCREASING THE BASE SALARY

2771
01:42:45,171 --> 01:42:47,507
SPHFOR SOME OF THE TRAINING

2772
01:42:47,507 --> 01:42:47,941
STIPENDS.

2773
01:42:47,941 --> 01:42:49,909
WE CAN'T BE COMPETITIVE WITH

2774
01:42:49,909 --> 01:42:51,444
WONDERFUL YOUNG PHYSICIANS WHO

2775
01:42:51,444 --> 01:42:52,979
ARE TRYING TO DECIDE AFTER

2776
01:42:52,979 --> 01:42:53,980
RESIDENCY IF THEY WILL BE ABLE

2777
01:42:53,980 --> 01:42:55,415
TO START A FAMILY, HAVE A HOME,

2778
01:42:55,415 --> 01:43:01,588
HOW WILL THEY DO THAT ON A SPY

2779
01:43:01,588 --> 01:43:02,555
STIPEND, AND COMPARE THAT TO

2780
01:43:02,555 --> 01:43:03,723
GOING OUT AND RUNNING A CLINIC

2781
01:43:03,723 --> 01:43:04,924
FOR TWICE THE AMOUNT.

2782
01:43:04,924 --> 01:43:06,359
SO I KNOW MONEY IS MONEY AND IF

2783
01:43:06,359 --> 01:43:07,694
YOU TAKE IT FROM ONE PLACE, YOU

2784
01:43:07,694 --> 01:43:08,895
DON'T HAVE IT IN ANOTHER.

2785
01:43:08,895 --> 01:43:11,531
BUT JUST A PLEA THERE, I RUN A

2786
01:43:11,531 --> 01:43:12,766
T32, WE'VE HAD A COUPLE OF CLOSE

2787
01:43:12,766 --> 01:43:14,501
CALLS IN GETTING M.D.s, BUT

2788
01:43:14,501 --> 01:43:16,369
IT'S JUST VERY, VERY HARD, VERY,

2789
01:43:16,369 --> 01:43:18,938
VERY HARD.

2790
01:43:18,938 --> 01:43:19,873
THAT'S IT.

2791
01:43:19,873 --> 01:43:21,574
>> ANNA ROSE, THANKS VERY
MUCH

2792
01:43:21,574 --> 01:43:23,009
AND BOTH OF THEM ARE IMPRINTED

2793
01:43:23,009 --> 01:43:25,845
IN MY BRAIN AND WE HAVE REQUESTS

2794
01:43:25,845 --> 01:43:30,750
FOR APPLICATIONS THAT THAT TACKE

2795
01:43:30,750 --> 01:43:32,152
POLYSUBSTANCE USE.

2796
01:43:32,152 --> 01:43:33,586
BUT THESE, THE NEED FOR

2797
01:43:33,586 --> 01:43:34,554
ATTRACTING YOUNG PHYSICIANS, AND

2798
01:43:34,554 --> 01:43:36,022
THE NEED FOR BETTER SALARIES,

2799
01:43:36,022 --> 01:43:38,758
I'LL BRING IT UP BUT THE WHOLE

2800
01:43:38,758 --> 01:43:40,160
CONSORTIUM NIH LEVEL BECAUSE I

2801
01:43:40,160 --> 01:43:41,761
THINK THAT PERTAINS TO EVERYONE.

2802
01:43:41,761 --> 01:43:43,396
AND I KNOW THAT SUSAN IS KEEPING

2803
01:43:43,396 --> 01:43:47,033
TRACK SO I'M GOING TO ADJOURN

2804
01:43:47,033 --> 01:43:48,168
NOW FOR ONE MINUTE OR TWO

2805
01:43:48,168 --> 01:43:50,370
MINUTES OR HOW MANY MINUTES,

2806
01:43:50,370 --> 01:43:50,703
SUSAN?

2807
01:43:50,703 --> 01:43:51,471
YOU'RE MUTED.

2808
01:43:51,471 --> 01:43:53,006
>> HOW ABOUT FIVE MINUTES?

2809
01:43:53,006 --> 01:43:56,776
LET'S GET BACK AT 2:35 AND WE'LL

2810
01:43:56,776 --> 01:43:57,877
START THE PRESENTATION AT THAT

2811
01:43:57,877 --> 01:43:58,378
POINT.

2812
01:43:58,378 --> 01:44:00,814
SORRY ABOUT THE VERY QUICK BIO

2813
01:44:00,814 --> 01:44:02,148
BREAK.

2814
01:44:02,148 --> 01:44:03,883
>> BETTER THAN --

2815
01:44:03,883 --> 01:44:05,785
>> I MEAN, IT'S BEEN SUCH
AN

2816
01:44:05,785 --> 01:44:06,386
INTERESTING CONVERSATION, SO
THANK YOU ALL.

2817
01:44:06,386 --> 01:44:07,608


2818
01:44:10,426 --> 01:44:13,095
>> TISHA, WHY DON'T YOU
START.

2819
01:44:13,095 --> 01:44:14,330
SORRY IT WAS SUCH A SHORT BREAK.

2820
01:44:14,330 --> 01:44:16,365
>> NO PROBLEM.

2821
01:44:16,365 --> 01:44:17,900
WELL, GOOD AFTERNOON, EVERYONE,

2822
01:44:17,900 --> 01:44:22,037
AND I WANT TO THANK NORA AND THE

2823
01:44:22,037 --> 01:44:23,639
REST OF THE NIDA TEAM FOR GIVING

2824
01:44:23,639 --> 01:44:24,740
ME THE CHANCE TO SHARE WITH YOU

2825
01:44:24,740 --> 01:44:25,975
AN UPDATE ON THE WORK THAT WE

2826
01:44:25,975 --> 01:44:28,677
ARE DOING AS PART OF THE JUSTICE

2827
01:44:28,677 --> 01:44:30,045
COMMUNITY OPIOID INNOVATION

2828
01:44:30,045 --> 01:44:31,480
NETWORK.

2829
01:44:31,480 --> 01:44:32,781
AND I ALSO WANT TO ACKNOWLEDGE

2830
01:44:32,781 --> 01:44:34,216
MY TEAM BEFORE I START.

2831
01:44:34,216 --> 01:44:35,417
I GET THE PRIVILEGE OF WORKING

2832
01:44:35,417 --> 01:44:36,752
WITH A REALLY WONDERFUL TEAM

2833
01:44:36,752 --> 01:44:39,088
HERE AT NIDA TO DO THIS WORK.

2834
01:44:39,088 --> 01:44:41,523
WE HAVE LORI, OUR SCIENCE

2835
01:44:41,523 --> 01:44:43,192
OFFICER, SHE'S THE ONLY SCIENCE

2836
01:44:43,192 --> 01:44:45,494
OFFICER FOR JCOIN, REALLY HELPS

2837
01:44:45,494 --> 01:44:46,495
CONNECT THE DOTS ACROSS THIS

2838
01:44:46,495 --> 01:44:48,230
REALLY COMPLEX NETWORK.

2839
01:44:48,230 --> 01:44:49,898
AND THEN IN ADDITION TO THEIR

2840
01:44:49,898 --> 01:44:51,567
OTHER DUTIES AS PART OF THE

2841
01:44:51,567 --> 01:44:54,436
SERVICES RESEARCH BRANCH, CARRIE

2842
01:44:54,436 --> 01:45:01,944
IS THE PO FOR JCOIN HUBS, JULIA,

2843
01:45:01,944 --> 01:45:04,213
SHELLEY, AND MARCY FITS-RANDOLPH

2844
01:45:04,213 --> 01:45:06,515
IS OUR MEDICAL OFFICER AND

2845
01:45:06,515 --> 01:45:08,651
LEADS -- WE DO A UNIFIED DSMB

2846
01:45:08,651 --> 01:45:10,085
ACROSS ALL OF THESE STUDIES SO

2847
01:45:10,085 --> 01:45:11,620
SHE LEADS OUR WORK THERE.

2848
01:45:11,620 --> 01:45:14,957
SO BEFORE I JUMP IN, I WANT TO

2849
01:45:14,957 --> 01:45:15,624
SHARE ACTUALLY THE PICTURE

2850
01:45:15,624 --> 01:45:17,026
THAT'S KIND OF HIDING IN THE

2851
01:45:17,026 --> 01:45:18,327
BACKGROUND HERE.

2852
01:45:18,327 --> 01:45:20,229
AND YOU'LL SEE THROUGHOUT THE

2853
01:45:20,229 --> 01:45:22,765
PRESENTATION TODAY SOME PICTURES

2854
01:45:22,765 --> 01:45:23,632
INTERSPERSED THAT HAVE COME TO

2855
01:45:23,632 --> 01:45:25,234
US BY WAY OF OUR INVESTIGATORS

2856
01:45:25,234 --> 01:45:27,636
AND PARTNERS IN THE NETWORK.

2857
01:45:27,636 --> 01:45:30,239
AND THIS PICTURE IN PARTICULAR

2858
01:45:30,239 --> 01:45:32,007
IS OF THE FRANKLIN COUNTY,

2859
01:45:32,007 --> 01:45:33,142
MASSACHUSETTS JAIL OF THE

2860
01:45:33,142 --> 01:45:33,909
WOMEN'S RECREATION AREA.

2861
01:45:33,909 --> 01:45:35,210
IT COMES FROM THE FRANKLIN

2862
01:45:35,210 --> 01:45:37,946
COUNTY SHERIFF'S DEPARTMENT, AND

2863
01:45:37,946 --> 01:45:40,182
I THINK THIS PICTURE TO ME IS

2864
01:45:40,182 --> 01:45:41,050
MEANINGFUL AND POIGNANT BECAUSE

2865
01:45:41,050 --> 01:45:43,118
I THINK IT CAPTURES IN MANY WAYS

2866
01:45:43,118 --> 01:45:44,386
THE HUMANITY OF THE POPULATION

2867
01:45:44,386 --> 01:45:47,890
THAT WE'RE WORKING WITH, BUT

2868
01:45:47,890 --> 01:45:49,591
ALSO MANY PEOPLE SPEND A PERIOD

2869
01:45:49,591 --> 01:45:51,593
OF TIME IN THESE SETTINGS IN

2870
01:45:51,593 --> 01:45:52,961
JAILS AND PRISONS, BUT THIS

2871
01:45:52,961 --> 01:45:54,463
PICTURE ALSO CAPTURES SORT OF

2872
01:45:54,463 --> 01:45:55,731
THE IDEA OF WHAT LIES BEYOND.

2873
01:45:55,731 --> 01:45:56,932
YOU SEE THE MOUNTAINS IN THE

2874
01:45:56,932 --> 01:45:59,601
DISTANCE OF THIS PICTURE, AND I

2875
01:45:59,601 --> 01:46:01,136
THINK THAT THAT CAPTURES THE

2876
01:46:01,136 --> 01:46:02,404
IDEA THAT IT'S REALLY IMPORTANT

2877
01:46:02,404 --> 01:46:03,572
TO THINK NOT JUST WHAT HAPPENS

2878
01:46:03,572 --> 01:46:05,140
IN JAILS AND PRISONS, BUT WHAT

2879
01:46:05,140 --> 01:46:06,675
HAPPENS AS PEOPLE RETURN BACK TO

2880
01:46:06,675 --> 01:46:08,010
THEIR HOMES, BACK TO THEIR

2881
01:46:08,010 --> 01:46:09,912
COMMUNITIES AND FAMILIES AND

2882
01:46:09,912 --> 01:46:10,979
THEIR CONNECTION AND THEIR PATH

2883
01:46:10,979 --> 01:46:14,383
TOWARD RECOVERY.

2884
01:46:14,383 --> 01:46:15,584
SO LET ME ALSO THEN KIND OF TURN

2885
01:46:15,584 --> 01:46:18,253
TO THE DATA HERE.

2886
01:46:18,253 --> 01:46:21,657
NORA KOPFED SOM COVERED SOME OFS

2887
01:46:21,657 --> 01:46:22,191
EARLIER.

2888
01:46:22,191 --> 01:46:24,426
WE ALL KNOW IN THIS AUDIENCE THE

2889
01:46:24,426 --> 01:46:25,527
IMPORTANCE OF UNDERSTANDING THAT

2890
01:46:25,527 --> 01:46:26,962
SO MANY PEOPLE ARE LOSING THEIR

2891
01:46:26,962 --> 01:46:28,364
LIVES EVERY YEAR TO THIS

2892
01:46:28,364 --> 01:46:29,398
OVERDOSE CRISIS, AND WE'VE KNOWN

2893
01:46:29,398 --> 01:46:31,266
FOR A LONG TIME THAT THE JUSTICE

2894
01:46:31,266 --> 01:46:33,435
SYSTEM IS A REALLY SENSITIVE

2895
01:46:33,435 --> 01:46:35,471
PLACE AND THAT THIS TRANSITION

2896
01:46:35,471 --> 01:46:36,438
PERIOD IS A SENSITIVE ONE.

2897
01:46:36,438 --> 01:46:38,440
WE HAVE MANY STUDIES OVER THE

2898
01:46:38,440 --> 01:46:40,342
LAST 10 TO 15 YEARS THAT HAVE

2899
01:46:40,342 --> 01:46:41,210
REALLY HIGHLIGHTED THAT THE TIME

2900
01:46:41,210 --> 01:46:42,444
AS PEOPLE ARE MOVING BETWEEN

2901
01:46:42,444 --> 01:46:45,381
JAILS AND PRISONS AND BACK INTO

2902
01:46:45,381 --> 01:46:47,182
THEIR COMMUNITIES IS A PERIOD OF

2903
01:46:47,182 --> 01:46:48,484
HEIGHTENED RISK OF RELAPSE AND

2904
01:46:48,484 --> 01:46:49,184
MORTALITY.

2905
01:46:49,184 --> 01:46:50,652
BUT MORE RECENT STATISTICS ALSO

2906
01:46:50,652 --> 01:46:51,620
POINT THAT THIS IS A PLACE WHERE

2907
01:46:51,620 --> 01:46:54,656
WE CAN INTERVENE AND CHANGE THE

2908
01:46:54,656 --> 01:46:55,224
TRAJECTORY.

2909
01:46:55,224 --> 01:46:56,158
RHODE ISLAND WAS ONE OF THE

2910
01:46:56,158 --> 01:46:57,893
FIRST STATES IN THE COUNTRY THAT

2911
01:46:57,893 --> 01:46:59,161
REALLY EMBRACED OFFERING ALL

2912
01:46:59,161 --> 01:47:00,763
THREE MEDICATIONS FOR OPIOID USE

2913
01:47:00,763 --> 01:47:02,231
DISORDER IN THEIR JAILS AND

2914
01:47:02,231 --> 01:47:04,867
PRISONS, AND WHEN THEY LOOKED AT

2915
01:47:04,867 --> 01:47:06,702
SOME MODELING DATA OF THAT, THEY

2916
01:47:06,702 --> 01:47:08,070
WERE ABLE TO PROJECT THAT THEY

2917
01:47:08,070 --> 01:47:10,706
COULD SEE AS MUCH AS A 31%

2918
01:47:10,706 --> 01:47:12,341
REDUCTION IN OVERALL OVERDOSE

2919
01:47:12,341 --> 01:47:14,443
RATES AT THE STATE LEVEL BY

2920
01:47:14,443 --> 01:47:16,211
EXPANDING THAT APPROACH.

2921
01:47:16,211 --> 01:47:17,546
WE'VE STARTED TO SEE STATES

2922
01:47:17,546 --> 01:47:20,482
ACROSS THE COUNTRY TAKE ON THIS

2923
01:47:20,482 --> 01:47:21,417
APPROACH.

2924
01:47:21,417 --> 01:47:22,518
SOME RECENT DATA FROM INDIANA

2925
01:47:22,518 --> 01:47:23,752
LOOKED AT THE PEOPLE THAT HAD

2926
01:47:23,752 --> 01:47:25,988
LOST THEIR LIVES AND LOOKED AT

2927
01:47:25,988 --> 01:47:27,423
WHETHER OR NOT WHAT SYSTEMS THEY

2928
01:47:27,423 --> 01:47:29,491
HAD CONTACT WITH IN THE YEAR

2929
01:47:29,491 --> 01:47:30,592
LEADING UP TO THEIR DEATH AND

2930
01:47:30,592 --> 01:47:32,728
FOUND THAT 1 IN 4 TOUCHED THE

2931
01:47:32,728 --> 01:47:34,062
JUSTICE SYSTEM, SO I THINK THIS

2932
01:47:34,062 --> 01:47:35,464
REALLY HIGHLIGHTS WHY THE

2933
01:47:35,464 --> 01:47:36,799
JUSTICE SYSTEM IS SUCH AN

2934
01:47:36,799 --> 01:47:38,600
IMPORTANT SYSTEM TO FOCUS ON AND

2935
01:47:38,600 --> 01:47:44,273
TO TARGET INTERVENTIONS TO.

2936
01:47:44,273 --> 01:47:45,707
BUT IT'S JUST NOT ENOUGH TO

2937
01:47:45,707 --> 01:47:47,142
TARGET THE JUSTICE SYSTEM AND

2938
01:47:47,142 --> 01:47:50,045
THINK ABOUT JAILS IN PRISONS IN

2939
01:47:50,045 --> 01:47:51,013
THE CONTINUITY OF CARE THAT

2940
01:47:51,013 --> 01:47:51,847
HAPPENS WHEN PEOPLE RETURN TO

2941
01:47:51,847 --> 01:47:52,881
THEIR HOMES.

2942
01:47:52,881 --> 01:47:54,283
AND IN THE COMMUNITIES, THERE'S

2943
01:47:54,283 --> 01:47:55,250
A LOT OF WORK TO DO.

2944
01:47:55,250 --> 01:47:57,085
THIS CAME UP IN THE DISCUSSION

2945
01:47:57,085 --> 01:47:57,653
EARLIER TODAY.

2946
01:47:57,653 --> 01:47:59,221
WE KNOW THAT THE BEHAVIORAL

2947
01:47:59,221 --> 01:48:01,423
HEALTH SYSTEM IS CHRONICALLY

2948
01:48:01,423 --> 01:48:03,592
UNDERRESOURCED, THAT THERE ARE

2949
01:48:03,592 --> 01:48:07,095
LOTS OF -- WORKFORCE CHALLENGES,

2950
01:48:07,095 --> 01:48:09,131
FUNDING SHORTAGES.

2951
01:48:09,131 --> 01:48:10,632
BUT WHAT I'M GOING TO HIGHLIGHT

2952
01:48:10,632 --> 01:48:11,967
HERE IS THAT EVEN KNOWING THAT,

2953
01:48:11,967 --> 01:48:13,769
EVEN WHEN PEOPLE MAKE THEIR WAY

2954
01:48:13,769 --> 01:48:17,506
INTO THE SYSTEM, PEOPLE WHO ARE

2955
01:48:17,506 --> 01:48:19,775
COMING INTO THE COMMUNITY

2956
01:48:19,775 --> 01:48:21,210
TREATMENT SYSTEM BY WAY OF THE

2957
01:48:21,210 --> 01:48:22,244
JUSTICE SYSTEM ARE LESS LIKELY

2958
01:48:22,244 --> 01:48:25,314
TO RECEIVE ACCESS TO EFFECTIVE

2959
01:48:25,314 --> 01:48:28,150
MEDICATIONS, SO 5% OF JUSTICE

2960
01:48:28,150 --> 01:48:28,851
REFERRED PATIENTS.

2961
01:48:28,851 --> 01:48:31,386
IN THIS ONE STUDY, RECEIVED

2962
01:48:31,386 --> 01:48:32,387
METHADONE OR BUPRENORPHINE

2963
01:48:32,387 --> 01:48:33,522
COMPARED TO 40% OF PEOPLE WHO

2964
01:48:33,522 --> 01:48:35,390
CAME INTO THE TREATMENT SYSTEM

2965
01:48:35,390 --> 01:48:36,258
THROUGH ANOTHER PATHWAY.

2966
01:48:36,258 --> 01:48:38,126
AND THIS IS A DISPARITY THAT'S

2967
01:48:38,126 --> 01:48:40,529
COSTING LIVES AND REALLY

2968
01:48:40,529 --> 01:48:41,730
DEMONSTRATES HOW CRITICAL IT IS

2969
01:48:41,730 --> 01:48:42,998
TO BUILD THESE PARTNERSHIPS

2970
01:48:42,998 --> 01:48:44,867
BETWEEN THE JUSTICE AND

2971
01:48:44,867 --> 01:48:48,136
COMMUNITY-BASED SYSTEMS IN ORDER

2972
01:48:48,136 --> 01:48:50,038
TO MAKE A DENT IN THAT.

2973
01:48:50,038 --> 01:48:50,939
THAT OBSERVATION IS REALLY SORT

2974
01:48:50,939 --> 01:48:53,242
OF WHAT LED US TO OUR VISION TO

2975
01:48:53,242 --> 01:48:54,676
THE WAY THAT WE'VE APPROACHED

2976
01:48:54,676 --> 01:48:56,144
THE WORK THAT WE'VE DONE IN

2977
01:48:56,144 --> 01:48:56,678
JCOIN.

2978
01:48:56,678 --> 01:48:58,447
J DN COIN WAS INITIALLY LAUNCHED

2979
01:48:58,447 --> 01:49:00,616
AS PART OF THE HEAL INITIATIVE

2980
01:49:00,616 --> 01:49:01,783
IN 2018.

2981
01:49:01,783 --> 01:49:03,285
IN 2018, WE WERE ABLE TO PUT OUT

2982
01:49:03,285 --> 01:49:04,987
A SET OF WHAT WE CALL

2983
01:49:04,987 --> 01:49:05,821
ACCELERATOR SUPPLEMENTS, THEN WE

2984
01:49:05,821 --> 01:49:07,990
DID A FULL LAUNCH OF THE NETWORK

2985
01:49:07,990 --> 01:49:09,291
IN 2019, AND I'LL BE DESCRIBING

2986
01:49:09,291 --> 01:49:11,593
THE WORK THAT WE'VE BEEN DOING

2987
01:49:11,593 --> 01:49:12,461
SINCE 2019 HERE, BUT ONE OF THE

2988
01:49:12,461 --> 01:49:14,429
THINGS THAT WE ORGANIZED AROUND

2989
01:49:14,429 --> 01:49:18,000
WAS A CORE MISSION THAT HAS

2990
01:49:18,000 --> 01:49:20,302
GUIDED EVERYTHING THAT WE HAVE

2991
01:49:20,302 --> 01:49:21,837
DO, AND THAT CORE MISSION IS A

2992
01:49:21,837 --> 01:49:23,038
VERY SIMPLE IDEA, THE SIMPLE

2993
01:49:23,038 --> 01:49:24,540
IDEA THAT EVERY INDIVIDUAL WHO'S

2994
01:49:24,540 --> 01:49:26,174
INVOLVED IN THE JUSTICE SYSTEM

2995
01:49:26,174 --> 01:49:27,476
THAT HAS A SUBSTANCE USE

2996
01:49:27,476 --> 01:49:29,044
DISORDER SHOULD HAVE ACCESS TO

2997
01:49:29,044 --> 01:49:29,645
EFFECTIVE TREATMENT AND THAT

2998
01:49:29,645 --> 01:49:31,380
THAT IS SOMETHING THAT SHOULD BE

2999
01:49:31,380 --> 01:49:32,881
TRUE, WHETHER SOMEONE IS

3000
01:49:32,881 --> 01:49:34,349
DETAINED IN A JAIL OR PRISON OR

3001
01:49:34,349 --> 01:49:36,952
THEY ARE IN THE COMMUNITY, AND

3002
01:49:36,952 --> 01:49:38,754
TO DO THAT, WE MUST REALLY BRING

3003
01:49:38,754 --> 01:49:39,888
TOGETHER PERSPECTIVES OF THE

3004
01:49:39,888 --> 01:49:40,822
JUSTICE PARTNERS OF THE

3005
01:49:40,822 --> 01:49:42,457
COMMUNITY PARTNERS, AND BECAUSE

3006
01:49:42,457 --> 01:49:44,960
WE ARE IN AN AGE OF THE

3007
01:49:44,960 --> 01:49:45,627
RESEARCHERS.

3008
01:49:45,627 --> 01:49:47,329
SO FIRST AND FOREMOST, OUR GOAL

3009
01:49:47,329 --> 01:49:49,097
AS A RESEARCH NETWORK IS TO

3010
01:49:49,097 --> 01:49:51,266
GENERATE NEW EVIDENCE ABOUT WHAT

3011
01:49:51,266 --> 01:49:52,601
WORKS, BUT ALSO HOW DO WE TAKE

3012
01:49:52,601 --> 01:49:53,735
THE THINGS THAT WE KNOW WORK AND

3013
01:49:53,735 --> 01:49:56,471
GET THEM INTO PRACTICE?

3014
01:49:56,471 --> 01:50:02,611
AND INTO WIDESPREAD PRACTICE.

3015
01:50:02,611 --> 01:50:04,947
THE REST OF OUR KIND OF CORE

3016
01:50:04,947 --> 01:50:05,948
PRINCIPLES ARE HOW DO WE DO

3017
01:50:05,948 --> 01:50:06,181
THAT.

3018
01:50:06,181 --> 01:50:07,916
WE WANT TO BUILD A NATIONAL

3019
01:50:07,916 --> 01:50:09,318
COLLABORATIVE NETWORK OF

3020
01:50:09,318 --> 01:50:11,053
RESEARCHERS WORKING WITH

3021
01:50:11,053 --> 01:50:11,687
PRACTITIONERS ACROSS BOTH

3022
01:50:11,687 --> 01:50:14,323
JUSTICE AND COMMUNITY-BASED

3023
01:50:14,323 --> 01:50:15,324
SETTINGS, THAT AS WE DO THIS

3024
01:50:15,324 --> 01:50:16,625
WORK, WE WANT TO BIELD OUT

3025
01:50:16,625 --> 01:50:18,794
RESOURCES FOR THE FIELD VERY

3026
01:50:18,794 --> 01:50:21,930
RAPIDLY, BECOME A GO-TO TRUSTED

3027
01:50:21,930 --> 01:50:24,433
RESOURCE FOR PRACTITIONERS AND

3028
01:50:24,433 --> 01:50:26,635
RESEARCHERS ALIKE TO BUILD

3029
01:50:26,635 --> 01:50:28,003
CAPACITY AND TO ANGLES TO THIS.

3030
01:50:28,003 --> 01:50:29,237
ONE IS ABOUT BUILDING CAPACITY

3031
01:50:29,237 --> 01:50:31,273
FOR RESEARCHERS TO DO WORK IN

3032
01:50:31,273 --> 01:50:33,141
THIS VERY COMPLEX SPACE, BUT THE

3033
01:50:33,141 --> 01:50:34,743
SECOND PIECE OF IT IS TO BUILD

3034
01:50:34,743 --> 01:50:36,945
CAPACITY IN THE COMMUNITY TO USE

3035
01:50:36,945 --> 01:50:40,282
AND ADOPT AND APPLY RESEARCH AND

3036
01:50:40,282 --> 01:50:41,350
APPLY SKILLS IN THEIR OWN WORK

3037
01:50:41,350 --> 01:50:41,817
TO DO THAT.

3038
01:50:41,817 --> 01:50:43,118
AND HOPEFULLY IF WE CAN BRING

3039
01:50:43,118 --> 01:50:45,921
ALL OF THIS TOGETHER, WE CAN BE

3040
01:50:45,921 --> 01:50:46,888
ONE PIECE SPEEDING THIS PROCESS

3041
01:50:46,888 --> 01:50:49,191
OF SCIENCE TO SOLUTIONS AND

3042
01:50:49,191 --> 01:50:50,892
CREATING MEANINGFUL FEEDBACK

3043
01:50:50,892 --> 01:50:51,093
LOONS.

3044
01:50:51,093 --> 01:50:52,294
SO THIS IS THE VISION THAT

3045
01:50:52,294 --> 01:50:53,395
GUIDES ALL THAT WE DO.

3046
01:50:53,395 --> 01:50:56,031
BUT SO WHAT IS J COIN, WHAT DOES

3047
01:50:56,031 --> 01:50:57,432
THIS ACTUALLY MEAN, WHAT ARE WE

3048
01:50:57,432 --> 01:50:57,866
AS A NETWORK?

3049
01:50:57,866 --> 01:51:00,569
WE HAVE FUNDED 13 RESEARCH HUBS.

3050
01:51:00,569 --> 01:51:04,706
THOSE RESEARCH HUBS ARE FUNDING

3051
01:51:04,706 --> 01:51:05,273
MULTISITE CLINICAL TRIALS.

3052
01:51:05,273 --> 01:51:06,908
THE MAJORITY OF THE RESEARCH --

3053
01:51:06,908 --> 01:51:08,043
BY MULTISITE, THEE ARE TRIALS

3054
01:51:08,043 --> 01:51:10,712
THAT ARE HAPPENING IN AT LEAST

3055
01:51:10,712 --> 01:51:12,581
FIVE COMMUNITIES, SO VERY LARGE

3056
01:51:12,581 --> 01:51:14,783
TRIALS COLLECTING DATA FOR MANY,

3057
01:51:14,783 --> 01:51:15,517
MANY PARTICIPANTS.

3058
01:51:15,517 --> 01:51:17,285
THE MAJORITY OF THESE ARE REALLY

3059
01:51:17,285 --> 01:51:18,820
LOOKING AT THIS PROCESS OF

3060
01:51:18,820 --> 01:51:21,390
LINKAGE AGAIN AS PEOPLE ARE

3061
01:51:21,390 --> 01:51:22,190
MOVING BETWEEN CARS RAL SETTINGS

3062
01:51:22,190 --> 01:51:24,459
BACK INTO THE COMMUNITY SO WE'RE

3063
01:51:24,459 --> 01:51:25,127
TESTING SEVEN DIFFERENT MODELS

3064
01:51:25,127 --> 01:51:26,361
OF WHAT THAT LINKAGE TO CARE

3065
01:51:26,361 --> 01:51:31,066
LOOKS LIKE.

3066
01:51:31,066 --> 01:51:32,434
SO HOPEFULLY IF WE GET TO THE

3067
01:51:32,434 --> 01:51:34,903
POINT WHERE WE HAVE RESULTS,

3068
01:51:34,903 --> 01:51:38,674
THERE'S A WORK GROUP THAT MEETS

3069
01:51:38,674 --> 01:51:39,474
PRETTY REGULARLY THAT THINKS

3070
01:51:39,474 --> 01:51:40,676
ABOUT THE WAYS ALL THESE STUDIES

3071
01:51:40,676 --> 01:51:41,810
ARE SIMILAR AND DIFFERENT TO

3072
01:51:41,810 --> 01:51:42,577
EACH OTHER AND WHAT THAT ALL

3073
01:51:42,577 --> 01:51:42,878
MEANS.

3074
01:51:42,878 --> 01:51:44,112
WE HAVE TWO STUDIES THAT ARE

3075
01:51:44,112 --> 01:51:46,782
LOOKING AT STATE-WIDE POLICY

3076
01:51:46,782 --> 01:51:47,049
ROLLOUTS.

3077
01:51:47,049 --> 01:51:48,750
AT THE TIME WE WERE SOLICITING

3078
01:51:48,750 --> 01:51:51,720
APPLICATIONS FOR JCOIN,

3079
01:51:51,720 --> 01:51:52,354
MASSACHUSETTS HAD RECENTLY

3080
01:51:52,354 --> 01:51:53,855
PASSED A LAW REQUIRING THAT THE

3081
01:51:53,855 --> 01:51:56,358
JAILS IN THAT STATE ALL OFFER

3082
01:51:56,358 --> 01:51:57,359
MEDICATIONS FOR ALL THREE FORMS

3083
01:51:57,359 --> 01:51:59,394
OF MEDICATIONS FOR OPIOID USE

3084
01:51:59,394 --> 01:52:00,495
DISORDER SO WE'VE BEEN ABLE TO

3085
01:52:00,495 --> 01:52:01,797
PARTNER WITH THAT PROCESS OF

3086
01:52:01,797 --> 01:52:04,599
ROLLING OUT THAT POLICY.

3087
01:52:04,599 --> 01:52:05,267
LIKEWISE IN NEW YORK, THERE WAS

3088
01:52:05,267 --> 01:52:07,135
AN EFFORT TO SCALE A MODEL

3089
01:52:07,135 --> 01:52:08,970
FOCUSED ON DRUG COURTS USING

3090
01:52:08,970 --> 01:52:11,673
WHAT'S CALLED OPIOID COURT

3091
01:52:11,673 --> 01:52:11,973
MODEL.

3092
01:52:11,973 --> 01:52:13,408
TWO OF OUR STUDIES ARE

3093
01:52:13,408 --> 01:52:14,543
COMPARATIVE EFFECTIVENESS TRIALS

3094
01:52:14,543 --> 01:52:15,610
LOOKING AT DIFFERENT

3095
01:52:15,610 --> 01:52:17,846
FORMULATIONS OF LONG-ACTING

3096
01:52:17,846 --> 01:52:18,180
MEDICATIONS.

3097
01:52:18,180 --> 01:52:19,948
AND THIS IS OFTEN A PRAGMATIC

3098
01:52:19,948 --> 01:52:21,917
KIND OF QUESTION LIKE WHICH

3099
01:52:21,917 --> 01:52:22,951
MEDICATION WORKS BEST, DO THEY

3100
01:52:22,951 --> 01:52:24,386
ALL WORK SIMILARLY.

3101
01:52:24,386 --> 01:52:26,555
SO THESE TWO STUDIES HAVE REALLY

3102
01:52:26,555 --> 01:52:28,924
HARMONIZED THEIR APPROACHES,

3103
01:52:28,924 --> 01:52:30,892
HAPPENING IN DIFFERENT PLACES,

3104
01:52:30,892 --> 01:52:32,728
ONE IS LOOKING AT THE

3105
01:52:32,728 --> 01:52:35,897
LONG-ACTING FORMULATION AT BEUP

3106
01:52:35,897 --> 01:52:38,834
BUPRENORPHINE, BOTH COMPARING

3107
01:52:38,834 --> 01:52:42,437
THIS TO THE LONG-ACTING VERSION

3108
01:52:42,437 --> 01:52:44,072
OF NALTREXONE, AS WELL AS

3109
01:52:44,072 --> 01:52:46,241
THERE'S SOME COMPONENTS TOO

3110
01:52:46,241 --> 01:52:47,008
COMPARED TO USUAL CARE.

3111
01:52:47,008 --> 01:52:48,310
THEN TWO OF OUR STUDIES ARE

3112
01:52:48,310 --> 01:52:49,511
REALLY LOOKING MORE AT THE HOW,

3113
01:52:49,511 --> 01:52:51,880
SO HOW DO YOU APPROACH THE

3114
01:52:51,880 --> 01:52:54,082
IMPLEMENTATION THING, AND WHICH

3115
01:52:54,082 --> 01:52:55,383
STRATEGIES WORK BEST TO HELP

3116
01:52:55,383 --> 01:52:56,151
SUPPORT ORGANIZATIONS THAT THEY

3117
01:52:56,151 --> 01:52:57,953
TRY TO ADOPT THESE BEST

3118
01:52:57,953 --> 01:52:59,588
PRACTICES.

3119
01:52:59,588 --> 01:53:01,022
ONE OF THE THINGS THAT HAS BEEN

3120
01:53:01,022 --> 01:53:02,991
IMPORTANT TO US AS WE STARTED

3121
01:53:02,991 --> 01:53:05,160
JCOIN WAS TO REALLY BUILD A

3122
01:53:05,160 --> 01:53:05,827
NATIONAL FOOTPRINT.

3123
01:53:05,827 --> 01:53:07,763
IF YOU LOOKED, WE DID A

3124
01:53:07,763 --> 01:53:10,365
LITERATURE REVIEW EARLY ON, AND

3125
01:53:10,365 --> 01:53:12,667
AT THAT TIME, A LOT OF THE

3126
01:53:12,667 --> 01:53:14,069
RESEARCH HAD COME REALLY OUT OF

3127
01:53:14,069 --> 01:53:16,037
THE NORTHEAST CORRIDOR, AND WE

3128
01:53:16,037 --> 01:53:17,105
WOULD HEAR THINGS FROM THE FIELD

3129
01:53:17,105 --> 01:53:18,373
ABOUT, WELL, THIS ISN'T RELEVANT

3130
01:53:18,373 --> 01:53:19,708
IN THIS PLACE OR THAT PLACE, IT

3131
01:53:19,708 --> 01:53:21,576
ONLY WORKS IN THESE KINDS OF

3132
01:53:21,576 --> 01:53:22,744
SETTINGS, SO WE'VE REALLY MADE A

3133
01:53:22,744 --> 01:53:25,714
PUSH TO MAKE SURE THAT WE'RE

3134
01:53:25,714 --> 01:53:26,915
GETTING REACH INTO LOTS OF

3135
01:53:26,915 --> 01:53:28,517
DIFFERENT PLACES SO THAT WE CAN

3136
01:53:28,517 --> 01:53:30,152
ADDRESS THAT AND MAKE SURE

3137
01:53:30,152 --> 01:53:31,386
THINGS WORK LOTS OF DIFFERENT

3138
01:53:31,386 --> 01:53:32,687
PLACES.

3139
01:53:32,687 --> 01:53:35,924
WE HAVE 140 COUNTIES AND 38

3140
01:53:35,924 --> 01:53:37,559
STATES IN PUERTO RICO

3141
01:53:37,559 --> 01:53:38,660
PARTICIPATING IN ONE CAPACITY OR

3142
01:53:38,660 --> 01:53:40,262
ANOTHER IN OUR RESEARCH.

3143
01:53:40,262 --> 01:53:41,229
SO FAR THROUGH THESE CLINICAL

3144
01:53:41,229 --> 01:53:43,131
TRIALS, WE'VE RECRUITED NEARLY

3145
01:53:43,131 --> 01:53:43,799
23,000 PARTICIPANTS.

3146
01:53:43,799 --> 01:53:45,233
SOME OF THIS IS FROM

3147
01:53:45,233 --> 01:53:47,002
ADMINISTRATIVE DATA, BUT WE'VE

3148
01:53:47,002 --> 01:53:48,403
ENROLLED LARGE NUMBERS OF

3149
01:53:48,403 --> 01:53:49,838
PARTICIPANTS AT STAFF IN MANY OF

3150
01:53:49,838 --> 01:53:53,308
THESE TRIALS.

3151
01:53:53,308 --> 01:53:54,509
PART OF THE GLUE THAT HOLDS

3152
01:53:54,509 --> 01:53:55,710
JCOIN TOGETHER, HOWEVER, IS OUR

3153
01:53:55,710 --> 01:53:56,244
SUPPORT CENTERS.

3154
01:53:56,244 --> 01:53:57,412
THEY HAVE A LOT OF FUNCTIONS.

3155
01:53:57,412 --> 01:53:59,581
WE'VE GOT TWO DIFFERENT SUPPORT

3156
01:53:59,581 --> 01:53:59,915
CENTERS.

3157
01:53:59,915 --> 01:54:03,919
ONE IS THE METHODOLOGY AND

3158
01:54:03,919 --> 01:54:04,519
ADVANCED ANALYTICS RESOURCE

3159
01:54:04,519 --> 01:54:04,820
CENTER.

3160
01:54:04,820 --> 01:54:06,555
THIS REALLY FOCUSES ON DATA,

3161
01:54:06,555 --> 01:54:08,390
DATA RESOURCES MODELING AND

3162
01:54:08,390 --> 01:54:09,491
SURVEY PROJECTS.

3163
01:54:09,491 --> 01:54:11,226
AND THEN WE HAVE A COORDINATION

3164
01:54:11,226 --> 01:54:13,829
AND TRANSLATION CENTER WHICH

3165
01:54:13,829 --> 01:54:16,765
FOCUSES ON, IN ADDITION TO

3166
01:54:16,765 --> 01:54:17,766
COORDINATION FUNCTIONS, REALLY

3167
01:54:17,766 --> 01:54:19,067
HOW WE GET THIS RESEARCH OUT

3168
01:54:19,067 --> 01:54:19,501
INTO PRACTICE.

3169
01:54:19,501 --> 01:54:21,269
AND YOU'LL SEE A LOT OF EXAMPLES

3170
01:54:21,269 --> 01:54:23,638
OF BOTH OF THEIR WORK TODAY.

3171
01:54:23,638 --> 01:54:25,507
BUT IN ADDITION TO THOSE 13

3172
01:54:25,507 --> 01:54:26,441
MULTISITE CLINICAL TRIALS, WE'VE

3173
01:54:26,441 --> 01:54:29,177
ACTUALLY EXECUTED 55 ADDITIONAL

3174
01:54:29,177 --> 01:54:29,845
RESEARCH PROTOCOLS.

3175
01:54:29,845 --> 01:54:32,881
MANY OF THESE ARE HAPPENING IN

3176
01:54:32,881 --> 01:54:35,951
THE MAARC AND CTCS ABOUT LU

3177
01:54:35,951 --> 01:54:37,786
HAPPENING IN THEIR RESEARCH HUB.

3178
01:54:37,786 --> 01:54:40,388
WE'VE GOT NATIONAL SURVEYS,

3179
01:54:40,388 --> 01:54:42,557
PILOT PROTOCOLS, MODELING AND

3180
01:54:42,557 --> 01:54:44,459
MAPPING STUDIES, DIVERSITY

3181
01:54:44,459 --> 01:54:45,694
SUPPLEMENTS AND SMALL GRANTS.

3182
01:54:45,694 --> 01:54:46,595
I'LL TELL MORE ABOUT THESE

3183
01:54:46,595 --> 01:54:47,863
COMPONENTS IN A MINUTE BUT THE

3184
01:54:47,863 --> 01:54:50,165
POINT I WANT TO MAKE HERE IS

3185
01:54:50,165 --> 01:54:51,600
THIS IS A REALLY ROBUST NETWORK

3186
01:54:51,600 --> 01:54:52,801
OF A LOT OF DIFFERENT

3187
01:54:52,801 --> 01:54:53,768
INTERRELATED RESEARCH HAPPENING

3188
01:54:53,768 --> 01:54:56,705
AT THE INTERSECTION OF JUSTICE

3189
01:54:56,705 --> 01:54:58,840
AND PUBLIC HEALTH AS IT PERTAINS

3190
01:54:58,840 --> 01:55:00,208
TO THE OVERDOSE CRISIS.

3191
01:55:00,208 --> 01:55:01,743
A CORE ELEMENT, A CORE FEATURE

3192
01:55:01,743 --> 01:55:05,213
THAT'S REALLY INFUSED WITH

3193
01:55:05,213 --> 01:55:07,082
EVERYTHING WE DO IS THE IDEA OF

3194
01:55:07,082 --> 01:55:07,782
THIS COLLABORATION.

3195
01:55:07,782 --> 01:55:09,217
I JUST WANT TO DEMONSTRATE FOR

3196
01:55:09,217 --> 01:55:12,087
YOU HOW IT IS INTERWOVEN THROUGH

3197
01:55:12,087 --> 01:55:14,656
THE WHOLE FABRIC OF THE NETWORK.

3198
01:55:14,656 --> 01:55:16,424
OUR HUBS IN EACH OF THE

3199
01:55:16,424 --> 01:55:18,159
COMMUNITIES ARE EXECUTING THE

3200
01:55:18,159 --> 01:55:19,361
TRIALS IN, HOW ARE

3201
01:55:19,361 --> 01:55:20,462
REPRESENTATIVES FROM BOTH THE

3202
01:55:20,462 --> 01:55:23,265
JUSTICE AND BEHAVIORAL HEALTH

3203
01:55:23,265 --> 01:55:23,832
PERSPECTIVES IN THOSE

3204
01:55:23,832 --> 01:55:24,866
COMMUNITIES AND OUR STEERING

3205
01:55:24,866 --> 01:55:26,568
COMMITTEE WHICH OVERSEES THE

3206
01:55:26,568 --> 01:55:27,969
WHOLE NETWORK, WE'VE GOT EACH OF

3207
01:55:27,969 --> 01:55:29,938
THE HUBS ALSO HAVE A NAMED

3208
01:55:29,938 --> 01:55:31,239
SENIOR JUSTICE AND BEHAVIORAL

3209
01:55:31,239 --> 01:55:32,440
HEALTH COMMUNITY PARTNER WHO'S

3210
01:55:32,440 --> 01:55:34,175
BEEN REALLY FOUNDATIONAL TO THE

3211
01:55:34,175 --> 01:55:36,344
WAY THEY'VE THOUGHT ABOUT THEIR

3212
01:55:36,344 --> 01:55:36,678
RESEARCH.

3213
01:55:36,678 --> 01:55:39,748
OUR COORDINATION AND TRANSLATION

3214
01:55:39,748 --> 01:55:41,182
CENTER ORGANIZES A NUMBER

3215
01:55:41,182 --> 01:55:41,516
COMMITTEES.

3216
01:55:41,516 --> 01:55:43,685
WE'VE GOT A NATIONAL

3217
01:55:43,685 --> 01:55:44,219
PRACTITIONER BOARD OF KEY

3218
01:55:44,219 --> 01:55:46,121
THOUGHT LEADERS ACROSS MULTIPLE

3219
01:55:46,121 --> 01:55:48,256
DIFFERENT DISCIPLINES AND

3220
01:55:48,256 --> 01:55:49,124
PERSPECTIVES, AS WELL AS A

3221
01:55:49,124 --> 01:55:51,960
STAKEHOLDER BOARD WHERE WE PULL

3222
01:55:51,960 --> 01:55:52,494
TOGETHER PROFESSIONAL

3223
01:55:52,494 --> 01:55:54,029
ASSOCIATIONS AGAIN FROM MULTIPLE

3224
01:55:54,029 --> 01:55:55,230
DISCIPLINES AND PERSPECTIVES,

3225
01:55:55,230 --> 01:55:56,731
AND WE DO A LOT OF WORK TOO TO

3226
01:55:56,731 --> 01:55:59,267
REACH OUT TO OUR COLLEAGUES AT

3227
01:55:59,267 --> 01:56:01,069
VARIOUS AGENCIES, THE DEPARTMENT

3228
01:56:01,069 --> 01:56:03,271
OF JUSTICE, SAMHSA, TO MAKE SURE

3229
01:56:03,271 --> 01:56:05,540
WE'RE AWARE OF AND COMMUNICATING

3230
01:56:05,540 --> 01:56:07,842
WITH OUR PARTNERS IN THE FEDERAL

3231
01:56:07,842 --> 01:56:12,447
STAYS WHO ARE SPACE WHO ARE DOIK

3232
01:56:12,447 --> 01:56:15,250
FNGHT.

3233
01:56:15,250 --> 01:56:15,784
WORK.

3234
01:56:15,784 --> 01:56:18,086
JUST OVER FOUR YEARS IN OF

3235
01:56:18,086 --> 01:56:18,853
LAUNCHING THE CORE OF THE

3236
01:56:18,853 --> 01:56:20,121
NETWORK, I THINK WE'RE NOW ON

3237
01:56:20,121 --> 01:56:22,223
THAT KIND OF UPHILL TRAJECTORY

3238
01:56:22,223 --> 01:56:23,625
OF PUBLICATIONS.

3239
01:56:23,625 --> 01:56:27,095
AT OUR LAST COUNT, WE HAD 157

3240
01:56:27,095 --> 01:56:27,429
PUBLICATIONS.

3241
01:56:27,429 --> 01:56:29,497
THIS QR CODE IF YOU SCAN IT WILL

3242
01:56:29,497 --> 01:56:32,200
TAKE YOU TO A PUBMED DATABASE

3243
01:56:32,200 --> 01:56:33,301
WHERE WE'RE GOING TO KEEP ADDING

3244
01:56:33,301 --> 01:56:39,541
TO THIS AS IT GROWS.

3245
01:56:39,541 --> 01:56:41,076
IT'S STILL GOING TO BE ANOTHER

3246
01:56:41,076 --> 01:56:43,111
COUPLE OF YEARS, COVID SLOWED

3247
01:56:43,111 --> 01:56:44,646
DOWN OUR CLINICAL TRIALS

3248
01:56:44,646 --> 01:56:46,381
ALTHOUGH SOME ARE NEARING

3249
01:56:46,381 --> 01:56:48,383
COMPLETION, IT'S STILL GOING TO

3250
01:56:48,383 --> 01:56:49,851
BE A COUPLE YEARS BEFORE WE HAVE

3251
01:56:49,851 --> 01:56:50,885
RESULTS FROM THOSE TRIALS, BUT

3252
01:56:50,885 --> 01:56:52,153
IN THE MEANTIME, WE'RE PUTTING

3253
01:56:52,153 --> 01:56:53,855
OUT A LOT INTO THE FIELD, AND

3254
01:56:53,855 --> 01:56:55,223
ONE WAY -- AND I THINK EVEN

3255
01:56:55,223 --> 01:56:56,958
THESE EARLY FINDINGS ARE HAVING

3256
01:56:56,958 --> 01:56:58,393
A SIGNIFICANT IMPACT ON OUR

3257
01:56:58,393 --> 01:56:59,894
UNDERSTANDING OF THESE ISSUES

3258
01:56:59,894 --> 01:57:01,196
AND ON THE FIELD.

3259
01:57:01,196 --> 01:57:04,132
ONE INDICATOR OF THAT IS IN THIS

3260
01:57:04,132 --> 01:57:04,432
RCR METRIC.

3261
01:57:04,432 --> 01:57:06,101
IF YOU'RE NOT FAMILIAR WITH THIS

3262
01:57:06,101 --> 01:57:08,670
METRIC, RCR STANDS FOR RELATIVE

3263
01:57:08,670 --> 01:57:09,804
CITATION RATIO.

3264
01:57:09,804 --> 01:57:11,773
THIS IS A METRIC CREATED BY

3265
01:57:11,773 --> 01:57:12,974
NIH'S OFFICE OF EXTRAMURAL

3266
01:57:12,974 --> 01:57:14,676
RESEARCH.

3267
01:57:14,676 --> 01:57:17,645
AND RCR2.41 REALLY JUST MEANS

3268
01:57:17,645 --> 01:57:19,047
THE PUBLICATIONS COMING OUT OF

3269
01:57:19,047 --> 01:57:20,815
JCOIN SO FAR ARE BEING CITED TWO

3270
01:57:20,815 --> 01:57:23,184
TO THREE TIMES MORE OFTEN THAN

3271
01:57:23,184 --> 01:57:24,753
THE AVERAGE PAPER PUBLISHED IN

3272
01:57:24,753 --> 01:57:32,627
THE FIELD OF THOSE PAPERS.

3273
01:57:32,627 --> 01:57:33,895
SO THAT'S ONE METRIC TO THINK

3274
01:57:33,895 --> 01:57:34,229
ABOUT IT.

3275
01:57:34,229 --> 01:57:36,331
RATHER THAN AS A COLLECTION OF

3276
01:57:36,331 --> 01:57:37,832
R01s TO REALLY CREATE

3277
01:57:37,832 --> 01:57:38,800
SYNERGIES AND COLLABORATIONS.

3278
01:57:38,800 --> 01:57:40,668
SO IN JCOIN, OUR NETWORK

3279
01:57:40,668 --> 01:57:42,771
INFRASTRUCTURE INCLUDES MULTIPLE

3280
01:57:42,771 --> 01:57:47,342
WORK GROUPS, AND THOSE WORK

3281
01:57:47,342 --> 01:57:50,178
GROUPS HELP FIND AREAS OF COMMON

3282
01:57:50,178 --> 01:57:50,779
INTEREST.

3283
01:57:50,779 --> 01:57:51,913
THEY'VE ALSO WORKED TO COME WITH

3284
01:57:51,913 --> 01:57:54,115
COMMON MEASURES THAT ARE

3285
01:57:54,115 --> 01:57:56,251
INCORPORATED INTO ALL OF THE

3286
01:57:56,251 --> 01:57:56,484
STUDIES.

3287
01:57:56,484 --> 01:57:57,719
ALL OF OUR INVESTIGATORS ARE

3288
01:57:57,719 --> 01:58:01,089
PUTTING THEIR DATA INTO A COMMON

3289
01:58:01,089 --> 01:58:02,290
PLATFORM, BUT WE'VE ALSO TRIED

3290
01:58:02,290 --> 01:58:03,725
TO SEE IF IT'S REALLY WORKING TO

3291
01:58:03,725 --> 01:58:06,561
BUILD RELATIONSHIPS.

3292
01:58:06,561 --> 01:58:08,196
SO THIS GRAPHIC I'M SHOWING YOU

3293
01:58:08,196 --> 01:58:09,397
HERE ON THE RIGHT COMES FROM A

3294
01:58:09,397 --> 01:58:13,001
PAPER PUBLISHED WITH -- BY LORI

3295
01:58:13,001 --> 01:58:14,636
AS THE SCIENCE OFFICER WITH SOME

3296
01:58:14,636 --> 01:58:17,338
OF OUR METHODOLOGY, OUR MAARC

3297
01:58:17,338 --> 01:58:18,440
COLLEAGUES.

3298
01:58:18,440 --> 01:58:19,340
REALLY WHAT IT DEMONSTRATES IS

3299
01:58:19,340 --> 01:58:21,476
THAT OVER TIME, THIS JCOIN

3300
01:58:21,476 --> 01:58:23,111
STRUCTURE HAS CREATED MORE

3301
01:58:23,111 --> 01:58:24,646
INTERIOR RELATIONSHIPS AMONG THE

3302
01:58:24,646 --> 01:58:26,114
DIFFERENT RESEARCH HUBS AND HAS

3303
01:58:26,114 --> 01:58:28,917
RESULTED IN LOTS OF DIFFERENT

3304
01:58:28,917 --> 01:58:30,118
COLLABORATIONS AND SYNERGIES, SO

3305
01:58:30,118 --> 01:58:31,453
THIS IS ONE OF THE REASONS WHY

3306
01:58:31,453 --> 01:58:33,822
WE THINK TAKING THIS NETWORK

3307
01:58:33,822 --> 01:58:34,856
APPROACH IS A USEFUL APPROACH

3308
01:58:34,856 --> 01:58:36,224
AND I THINK IN THE FUTURE, WE'LL

3309
01:58:36,224 --> 01:58:38,626
SEE MORE OF THAT.

3310
01:58:38,626 --> 01:58:39,694
BUT I WANT TO GIVE YOU JUST A

3311
01:58:39,694 --> 01:58:41,663
COUPLE OF EXAMPLES OF INDIVIDUAL

3312
01:58:41,663 --> 01:58:43,565
PAPERS AND THE WAY WE THINK

3313
01:58:43,565 --> 01:58:45,266
ABOUT TRANSLATING THAT RESEARCH

3314
01:58:45,266 --> 01:58:46,000
FOR IMPACT.

3315
01:58:46,000 --> 01:58:49,204
THIS IS A PAPER FROM THE

3316
01:58:49,204 --> 01:58:50,705
MASSACHUSETTS JCOIN HUB THAT WAS

3317
01:58:50,705 --> 01:58:53,741
LOOKING AT THAT EFFORT TO OFFER

3318
01:58:53,741 --> 01:58:56,144
ALL THREE FORMS OF MEDICATION IN

3319
01:58:56,144 --> 01:58:56,578
MASSACHUSETTS JAILS.

3320
01:58:56,578 --> 01:58:58,546
THE TITLE OF THE PAPER IS

3321
01:58:58,546 --> 01:59:00,381
"UNCOMMON AND PREVENTABLE

3322
01:59:00,381 --> 01:59:01,816
PERCEPTIONS OF DIVERSION OF

3323
01:59:01,816 --> 01:59:03,551
MEDICATION FOR OPIOID USE

3324
01:59:03,551 --> 01:59:03,952
DISORDER."

3325
01:59:03,952 --> 01:59:05,520
THIS PAPER WAS BASED ON SOME OF

3326
01:59:05,520 --> 01:59:07,255
THEIR EARLY WORK, AND IT'S VERY

3327
01:59:07,255 --> 01:59:08,323
RESPONSIVE TO A CONCERN WE OFTEN

3328
01:59:08,323 --> 01:59:10,425
HEAR FROM OUR JUSTICE PARTNERS

3329
01:59:10,425 --> 01:59:11,192
ABOUT REASONS WHY THEY DON'T

3330
01:59:11,192 --> 01:59:14,362
WANT TO OFFER BUPRENORPHINE

3331
01:59:14,362 --> 01:59:15,897
BECAUSE THEY'RE AFRAID OF

3332
01:59:15,897 --> 01:59:16,965
DIVERSION, THEY'RE AFRAID IT

3333
01:59:16,965 --> 01:59:19,167
CREATES A SAFETY AND SECURITY

3334
01:59:19,167 --> 01:59:20,468
RISK WITHIN THERE'S SECURE

3335
01:59:20,468 --> 01:59:22,003
ENVIRONMENTS, AND SO WHAT THIS

3336
01:59:22,003 --> 01:59:26,407
PAPER DID IS IT SHOWED THAT IN

3337
01:59:26,407 --> 01:59:27,242
MASSACHUSETTS, THEY'VE BEEN ABLE

3338
01:59:27,242 --> 01:59:28,610
TO COME UP WITH A SET OF

3339
01:59:28,610 --> 01:59:29,878
PROTOCOLS TO REALLY MITIGATE

3340
01:59:29,878 --> 01:59:33,047
THOSE RISKS AND MAKE THEM VERY

3341
01:59:33,047 --> 01:59:37,218
MANAGEABLE.

3342
01:59:37,218 --> 01:59:38,720
FROM THIS PUBLICATION, WE PUT

3343
01:59:38,720 --> 01:59:40,889
THEM IN OUR NEWSLETTER IN A NICE

3344
01:59:40,889 --> 01:59:41,456
LITTLE SUMMARY.

3345
01:59:41,456 --> 01:59:43,558
WE'VE GOT 5,000 NEWSLETTER

3346
01:59:43,558 --> 01:59:45,727
SUBSCRIBERS, AND THIS GETS

3347
01:59:45,727 --> 01:59:47,595
BLASTED OUT.

3348
01:59:47,595 --> 01:59:49,764
AND THEN FOR SOME OF OUR PAPERS,

3349
01:59:49,764 --> 01:59:51,599
WE FOLLOW UP WITH THAT WITH A

3350
01:59:51,599 --> 01:59:52,367
WEBINAR, PARTICULARLY WHEN WE'RE

3351
01:59:52,367 --> 01:59:53,568
SENSING THERE'S A LOT OF

3352
01:59:53,568 --> 01:59:55,236
INTEREST IN THE FIELD, SO JUST

3353
01:59:55,236 --> 01:59:56,204
LAST DECEMBER THERE WAS A

3354
01:59:56,204 --> 01:59:57,505
WEBINAR FROM THE INVESTIGATORS

3355
01:59:57,505 --> 01:59:59,440
ON THIS THAT WAS WELL ATTENDED.

3356
01:59:59,440 --> 02:00:01,209
ANOTHER UNIQUE DISSEMINATION

3357
02:00:01,209 --> 02:00:02,844
PATHWAY THAT WE HAVE WITHIN

3358
02:00:02,844 --> 02:00:05,480
JCOIN IS A PODCAST THAT HAS

3359
02:00:05,480 --> 02:00:07,515
GOTTEN QUITE POPULAR,

3360
02:00:07,515 --> 02:00:09,417
45 EPISODES SO FAR, 13,000

3361
02:00:09,417 --> 02:00:10,685
DOWNLOADS, AND THEY'VE

3362
02:00:10,685 --> 02:00:11,920
INTERVIEWED MOST IF NOT ALL OF

3363
02:00:11,920 --> 02:00:13,321
THE INVESTIGATORS AT THIS POINT

3364
02:00:13,321 --> 02:00:16,090
AND THEY DO LOTS OF NICE LITTLE

3365
02:00:16,090 --> 02:00:16,958
INTERESTING EPISODES ON

3366
02:00:16,958 --> 02:00:20,195
DIFFERENT FINDINGS OR

3367
02:00:20,195 --> 02:00:20,495
PRINCIPLES.

3368
02:00:20,495 --> 02:00:22,230
WE ALSO TURN THIS FINDING INTO

3369
02:00:22,230 --> 02:00:23,765
AN INFOGRAPHIC SORT OF

3370
02:00:23,765 --> 02:00:25,867
DISTILLING DOWN THE KEY ELEMENTS

3371
02:00:25,867 --> 02:00:28,203
OF THE FINDING, AND THEN BLAST

3372
02:00:28,203 --> 02:00:29,737
OUT PIECES OF THIS ON SOCIAL

3373
02:00:29,737 --> 02:00:31,839
MEDIA REALLY TO CREATE

3374
02:00:31,839 --> 02:00:32,340
ENGAGEMENT.

3375
02:00:32,340 --> 02:00:35,510
AND WHAT WE'VE HEARD FROM OUR

3376
02:00:35,510 --> 02:00:37,478
PARTNERS WHO WERE PART OF THIS

3377
02:00:37,478 --> 02:00:40,114
WORK IS THAT THIS IS HELPFUL TO

3378
02:00:40,114 --> 02:00:41,516
THEM BECAUSE WHENEVER THEY'RE

3379
02:00:41,516 --> 02:00:43,918
GETTING CALLS FROM OTHER JAILS,

3380
02:00:43,918 --> 02:00:46,187
IT GIVES THEM A RESOURCE TO

3381
02:00:46,187 --> 02:00:47,755
POINT PEOPLE TO AND HELPS THEM

3382
02:00:47,755 --> 02:00:53,761
MANAGE THAT INTEREST LEVEL.

3383
02:00:53,761 --> 02:00:55,597
IN THIS CASE ONE OF THE THINGS

3384
02:00:55,597 --> 02:00:57,999
WE'VE HEARD BACK, THERE WAS

3385
02:00:57,999 --> 02:00:59,434
OUTREACH FROM MAIN JAILS AND

3386
02:00:59,434 --> 02:01:01,169
THOSE MAINE JAILS HAVE ADOPTED

3387
02:01:01,169 --> 02:01:02,036
THE DIVERSION PROTOCOLS

3388
02:01:02,036 --> 02:01:03,204
DEVELOPED IN MASSACHUSETTS AND

3389
02:01:03,204 --> 02:01:05,540
IT IS I THINK IN PART A RESULT

3390
02:01:05,540 --> 02:01:06,608
OF THIS SORT OF TRANSLATION

3391
02:01:06,608 --> 02:01:09,110
STRATEGY TO REALLY GET THE WORD

3392
02:01:09,110 --> 02:01:10,411
OUT TO SUPPORT THE WORK OF

3393
02:01:10,411 --> 02:01:13,381
OTHERS TO DO THAT.

3394
02:01:13,381 --> 02:01:14,682
A SECOND EXAMPLE ALSO FROM

3395
02:01:14,682 --> 02:01:15,550
MASSACHUSETTS, I THINK

3396
02:01:15,550 --> 02:01:16,584
ILLUSTRATES SOME DIFFERENT

3397
02:01:16,584 --> 02:01:18,653
PRINCIPLES OF HOW WE TAKE OUR

3398
02:01:18,653 --> 02:01:21,522
APPROACH TO THIS TRANSLATION.

3399
02:01:21,522 --> 02:01:23,258
HERE THIS PUBLICATION FOCUSED ON

3400
02:01:23,258 --> 02:01:24,659
A BUDGET IMPACT TOOL RELATED TO

3401
02:01:24,659 --> 02:01:26,928
HOW TO INCORPORATE MEDICATIONS

3402
02:01:26,928 --> 02:01:30,231
IN TO THE JAILS.

3403
02:01:30,231 --> 02:01:32,300
AND AN UNUSUAL FEATURE HERE, IF

3404
02:01:32,300 --> 02:01:34,402
YOU LOOK AT THE CO-AUTHOR LIST,

3405
02:01:34,402 --> 02:01:36,704
THE SHERIFF OF MIDDLESEX HOUSE

3406
02:01:36,704 --> 02:01:38,806
OF CORRECTIONS IN MASSACHUSETTS,

3407
02:01:38,806 --> 02:01:42,710
AS WELL AS THE PERSON IN CHARGE

3408
02:01:42,710 --> 02:01:44,312
OF THE BUDGET IN THE MIDDLESEX

3409
02:01:44,312 --> 02:01:49,150
JAILS AND THEN -- WHO LEADS THE

3410
02:01:49,150 --> 02:01:50,184
TREATMENT WORK WITHIN THE

3411
02:01:50,184 --> 02:01:51,319
FRANKLIN COUNTY JAILS IN

3412
02:01:51,319 --> 02:01:52,387
MASSACHUSETTS, WHERE MANY OF THE

3413
02:01:52,387 --> 02:01:53,288
PICTURES I'VE BEEN SHOWING YOU

3414
02:01:53,288 --> 02:01:53,655
ARE.

3415
02:01:53,655 --> 02:01:55,256
AND THEY'RE CO-AUTHORS OF THIS

3416
02:01:55,256 --> 02:01:56,024
PUBLICATION, AND THIS

3417
02:01:56,024 --> 02:01:57,659
PUBLICATION IN PART WAS SPARKED

3418
02:01:57,659 --> 02:01:58,826
FROM A CONVERSATION BETWEEN THE

3419
02:01:58,826 --> 02:02:01,329
INVESTIGATORS AND THE ECONOMISTS

3420
02:02:01,329 --> 02:02:02,997
WHO ARE PART OF THE VARIOUS

3421
02:02:02,997 --> 02:02:05,833
JCOIN STUDIES ABOUT HOW THEY

3422
02:02:05,833 --> 02:02:07,368
WERE THINKING ABOUT HOW THEY

3423
02:02:07,368 --> 02:02:09,137
WERE GOING TO PRACTICALLY

3424
02:02:09,137 --> 02:02:10,038
IMPLEMENT THIS GUIDANCE.

3425
02:02:10,038 --> 02:02:10,905
WHETHER THEY WERE GOING TO

3426
02:02:10,905 --> 02:02:12,540
BECOME AN OTP OR SUBCONTRACT IT

3427
02:02:12,540 --> 02:02:14,509
OUT IS SORT OF A MAKE OR BUY

3428
02:02:14,509 --> 02:02:15,310
QUESTION.

3429
02:02:15,310 --> 02:02:17,011
AND SO THIS PUBLICATION IS THE

3430
02:02:17,011 --> 02:02:19,080
RESULT BUT THEY ALSO DEVELOPED A

3431
02:02:19,080 --> 02:02:21,916
DOWNLOADABLE TOOL THAT WAS

3432
02:02:21,916 --> 02:02:23,551
PUBLISHED AT THE SAME TIME AS

3433
02:02:23,551 --> 02:02:24,419
THIS PUBLICATION THAT OTHER

3434
02:02:24,419 --> 02:02:25,820
JAILS CAN GO AND DOWNLOAD AND

3435
02:02:25,820 --> 02:02:28,890
PUT IN WHAT THEIR PARTICULAR

3436
02:02:28,890 --> 02:02:31,693
ASSUMPTIONS ARE AND SEE BASED ON

3437
02:02:31,693 --> 02:02:32,827
THE EXPERIENCES OF THESE JAILS,

3438
02:02:32,827 --> 02:02:34,028
I BELIEVE THERE'S ALSO

3439
02:02:34,028 --> 02:02:35,997
CONSULTATION WITH SOME OF THE

3440
02:02:35,997 --> 02:02:38,232
MARYLAND JAIL TO ANOTHER STUDY

3441
02:02:38,232 --> 02:02:40,468
WITHIN THE JCOIN NETWORK.

3442
02:02:40,468 --> 02:02:40,668
 DOING

3443
02:02:40,668 --> 02:02:40,902
THAT.

3444
02:02:40,902 --> 02:02:43,738
THEY DID A WEBINAR AS WITH THE

3445
02:02:43,738 --> 02:02:45,373
OTHER PAPER, BUT ONE OF THE

3446
02:02:45,373 --> 02:02:47,208
OTHER UNUSUAL THINGS JUST FOUR

3447
02:02:47,208 --> 02:02:48,843
MONTHS AFTER THIS PAPER WAS

3448
02:02:48,843 --> 02:02:50,845
PUBLISHED, WE HAD THE

3449
02:02:50,845 --> 02:02:52,213
INVESTIGATORS BEING APPROACHED

3450
02:02:52,213 --> 02:02:56,584
AND INVITED BY SAMHSA'S GAIN

3451
02:02:56,584 --> 02:02:58,886
CENTER TO COME AND PRESENT WHERE

3452
02:02:58,886 --> 02:03:00,321
THEY BRING IN TEAMS FROM ACROSS

3453
02:03:00,321 --> 02:03:04,625
THE COUNTRY WHO ARE OUT

3454
02:03:04,625 --> 02:03:05,693
THERE TRYING TO DO THIS WORK AND

3455
02:03:05,693 --> 02:03:06,694
TO TALK THROUGH THIS TOOL AND

3456
02:03:06,694 --> 02:03:10,164
HOW THE TOOL CAN BE USED.

3457
02:03:10,164 --> 02:03:11,699
WE ALSO DO MAKE SURE WE ARE

3458
02:03:11,699 --> 02:03:12,700
GENERATING DATA AND RESOURCES

3459
02:03:12,700 --> 02:03:14,202
THAT ARE USEFUL FOR THE RESEARCH

3460
02:03:14,202 --> 02:03:14,535
COMMUNITY.

3461
02:03:14,535 --> 02:03:16,738
WE'VE GOT A NICE DATABASE OF

3462
02:03:16,738 --> 02:03:18,272
DIFFERENT POLICIES THAT ARE

3463
02:03:18,272 --> 02:03:19,140
PARTICULARLY RELEVANT IN THE

3464
02:03:19,140 --> 02:03:20,842
WORK THAT WE DO THAT MIGHT BE OF

3465
02:03:20,842 --> 02:03:24,479
INTEREST TO OTHERS AROUND LAWS

3466
02:03:24,479 --> 02:03:27,081
ABOUT DRUG INDUCED HOMICIDE

3467
02:03:27,081 --> 02:03:29,484
LAWS, MEDICAID COVERAGE FROM

3468
02:03:29,484 --> 02:03:31,686
MOUD, THINGS OF THAT NATURE.

3469
02:03:31,686 --> 02:03:34,822
WE'VE GOT OUR CORE MEASURES

3470
02:03:34,822 --> 02:03:35,256
PUBLISHED.

3471
02:03:35,256 --> 02:03:38,860
THIS IS A TOOL I THINK IS REALLY

3472
02:03:38,860 --> 02:03:40,294
COOL CALLED THE OPIOID

3473
02:03:40,294 --> 02:03:42,730
ENVIRONMENT POLICY SCAN.

3474
02:03:42,730 --> 02:03:45,133
THE TEAM DOES A LOT OF REALLY

3475
02:03:45,133 --> 02:03:46,768
FANTASTIC GEOSPATIAL ANALYSES,

3476
02:03:46,768 --> 02:03:48,636
AND THEY TOOK AND COMBINED

3477
02:03:48,636 --> 02:03:50,471
MULTIPLE EXISTING DATASETS,

3478
02:03:50,471 --> 02:03:51,706
GEOCODED THEM AND PUT THEM INTO

3479
02:03:51,706 --> 02:03:53,141
A SINGLE RESOURCE TOOL THAT

3480
02:03:53,141 --> 02:03:55,276
OTHER RESEARCHERS CAN DOWNLOAD

3481
02:03:55,276 --> 02:03:56,511
AND USE FOR WHATEVER YOUR OWN

3482
02:03:56,511 --> 02:03:58,479
RESEARCH QUESTIONS ARE.

3483
02:03:58,479 --> 02:04:00,314
AS AN EXAMPLE OF ONE OF OUR

3484
02:04:00,314 --> 02:04:01,082
COLLABORATIONS WITH OTHER

3485
02:04:01,082 --> 02:04:04,051
FEDERAL AGENCIES, A TEAM FROM

3486
02:04:04,051 --> 02:04:06,220
SEVERAL DIFFERENT INSTITUTIONS

3487
02:04:06,220 --> 02:04:07,755
LED BY THE UNIVERSITY OF

3488
02:04:07,755 --> 02:04:10,024
CHICAGO, BY ROGAN AND ABRAHAM

3489
02:04:10,024 --> 02:04:12,760
AND ANDREWS DID WORK TO LOOK AT

3490
02:04:12,760 --> 02:04:14,429
ALL THE FUNDING THAT WENT OUT

3491
02:04:14,429 --> 02:04:16,097
FROM -- I BELIEVE IT WAS 11 OR

3492
02:04:16,097 --> 02:04:18,199
12 DIFFERENT FUNDING AGENCIES IN

3493
02:04:18,199 --> 02:04:22,303
2019 AND 2020 AND MAPPED OUT AND

3494
02:04:22,303 --> 02:04:23,938
ANALYZED AS TO RELATES TO LOTS

3495
02:04:23,938 --> 02:04:24,906
OF DIFFERENT FACTORS.

3496
02:04:24,906 --> 02:04:26,407
THIS IS AN INTERACTIVE MAP THAT

3497
02:04:26,407 --> 02:04:28,743
YOU CAN ACCESS AND LO LOOK AT TE

3498
02:04:28,743 --> 02:04:29,844
DATA YOURSELF, AND WE'RE WORKING

3499
02:04:29,844 --> 02:04:31,245
TO MAKE SURE THE DATA THAT CAN

3500
02:04:31,245 --> 02:04:33,448
BE EASILY SHARED WIDELY IS BEING

3501
02:04:33,448 --> 02:04:35,416
MOVED ON TO THE HEAL DATA

3502
02:04:35,416 --> 02:04:36,951
PLATFORM AND WE HAVE AN INTERNAL

3503
02:04:36,951 --> 02:04:39,887
PLATFORM TO FACILITATE EARLIER

3504
02:04:39,887 --> 02:04:41,656
STAGE SHARING BEFORE IT'S READY

3505
02:04:41,656 --> 02:04:48,196
FOR PUBLIC CONSUMPTION.

3506
02:04:48,196 --> 02:04:49,397
AS WE TRACK THE DATA ON THE

3507
02:04:49,397 --> 02:04:52,033
REACH WE'RE HAVING, SO FAR WE'VE

3508
02:04:52,033 --> 02:04:52,800
ENGAGED 16,000 UNIQUE

3509
02:04:52,800 --> 02:04:53,668
STAKEHOLDERS FROM OUR PUBLIC

3510
02:04:53,668 --> 02:04:54,969
EVENTS AND THE TAKEAWAY I WANT

3511
02:04:54,969 --> 02:04:57,171
YOU TO GET FROM THIS CHART IS

3512
02:04:57,171 --> 02:04:58,406
THAT WE'RE REACHING LOTS OF

3513
02:04:58,406 --> 02:04:58,906
DIFFERENT AUDIENCES.

3514
02:04:58,906 --> 02:05:00,708
SO RESEARCHERS, STATE AND LOCAL

3515
02:05:00,708 --> 02:05:02,043
GOVERNMENT, LIVED EXPERIENCE,

3516
02:05:02,043 --> 02:05:03,611
AND THAT IS PART OF OUR GOAL,

3517
02:05:03,611 --> 02:05:05,046
THAT WE'RE ALWAYS HAVING ALL OF

3518
02:05:05,046 --> 02:05:06,581
THESE DIFFERENT AUDIENCES IN

3519
02:05:06,581 --> 02:05:09,517
MIND IN MAKING SURE TO CREATE

3520
02:05:09,517 --> 02:05:10,718
PRODUCTS THAT ARE OF INTEREST TO

3521
02:05:10,718 --> 02:05:12,720
VARIOUS AUDIENCES.

3522
02:05:12,720 --> 02:05:15,756
AND WHILE WE'RE WAITING FOR THE

3523
02:05:15,756 --> 02:05:17,191
RESULTS OF THE CLINICAL TRIALS,

3524
02:05:17,191 --> 02:05:19,126
THERE ARE SOME INDICATIONS JUST

3525
02:05:19,126 --> 02:05:19,894
ANECDOTALLY THAT WE'VE HEARD

3526
02:05:19,894 --> 02:05:21,429
ABOUT THAT ARE REALLY

3527
02:05:21,429 --> 02:05:23,064
DEMONSTRATING TO ME THAT WE ARE

3528
02:05:23,064 --> 02:05:24,932
HAVING A REAL IMPACT IN THE

3529
02:05:24,932 --> 02:05:25,366
FIELD.

3530
02:05:25,366 --> 02:05:27,535
WE'VE HEARD OF 15 DIFFERENT

3531
02:05:27,535 --> 02:05:28,202
JURISDICTIONS THAT HAVE

3532
02:05:28,202 --> 02:05:30,938
PERMANENTLY ADDED OR EXPANDED

3533
02:05:30,938 --> 02:05:32,139
THEIR OFFERING OF MEDICATIONS

3534
02:05:32,139 --> 02:05:33,875
FOR OPIOID USE DISORDER AS PART

3535
02:05:33,875 --> 02:05:35,843
OF THEIR USUAL JAIL SERVICES DUE

3536
02:05:35,843 --> 02:05:37,612
TO THEIR JCOIN EXPOSURE.

3537
02:05:37,612 --> 02:05:40,014
JUST ONE EXAMPLE OF THAT IS A

3538
02:05:40,014 --> 02:05:41,849
FLORIDA JAIL IN A TRIAL LED BY

3539
02:05:41,849 --> 02:05:42,950
WISCONSIN THROUGH OUR

3540
02:05:42,950 --> 02:05:43,584
COORDINATION TRANSLATION CENTER

3541
02:05:43,584 --> 02:05:45,253
THAT COMPLETED THEIR OTP

3542
02:05:45,253 --> 02:05:47,288
CERTIFICATION.

3543
02:05:47,288 --> 02:05:49,257
WE'VE HEARD FROM OUR KENTUCKY

3544
02:05:49,257 --> 02:05:51,125
PARTNERS THAT THEY CREDIT THE

3545
02:05:51,125 --> 02:05:52,560
OPPORTUNITY TO WORK TOGETHER

3546
02:05:52,560 --> 02:05:54,262
THROUGH JCOIN AS SOMETHING THAT

3547
02:05:54,262 --> 02:05:55,730
HAS STRENGTHENED THEIR

3548
02:05:55,730 --> 02:05:57,031
RELATIONSHIP AND CONTRIBUTED TO

3549
02:05:57,031 --> 02:06:00,201
THEIR OWN EFFORTS IN KENTUCKY TO

3550
02:06:00,201 --> 02:06:02,503
APPLY FOR AN 1115 WAIVER TO

3551
02:06:02,503 --> 02:06:04,138
EXPAND THEIR OFFERINGS OF

3552
02:06:04,138 --> 02:06:05,873
MOUDs IN JAILS WITHIN

3553
02:06:05,873 --> 02:06:07,275
KENTUCKY, AND IN INDIANA, WE

3554
02:06:07,275 --> 02:06:09,143
HAVE A PI THAT'S ON A STATE TASK

3555
02:06:09,143 --> 02:06:11,445
FORCE USING HIS JCOIN DATA TO

3556
02:06:11,445 --> 02:06:12,079
RECOMMEND UNIVERSAL SCREENING

3557
02:06:12,079 --> 02:06:14,582
FOR JUVENILES AT ARREST.

3558
02:06:14,582 --> 02:06:15,483
THERE'S STATE LEGISLATION

3559
02:06:15,483 --> 02:06:15,917
PENDING.

3560
02:06:15,917 --> 02:06:17,985
THEN IN THE CATEGORY OF KIND OF

3561
02:06:17,985 --> 02:06:19,620
UNEXPECTED BUT REALLY VERY

3562
02:06:19,620 --> 02:06:22,590
WELCOMED FINDINGS, MANY OF OUR

3563
02:06:22,590 --> 02:06:25,693
LINKAGE FACILITATION EFFORTS USE

3564
02:06:25,693 --> 02:06:27,828
PEER MODELS BUT HAVE FOUND THAT

3565
02:06:27,828 --> 02:06:29,030
SOMETIMES IT QUITE HARD TO HIRE

3566
02:06:29,030 --> 02:06:31,766
PEERS THAT HAVE A HISTORY OF

3567
02:06:31,766 --> 02:06:32,333
JUSTICE INVOLVEMENT.

3568
02:06:32,333 --> 02:06:34,502
WE'VE HAD TWO HUBS THAT HAVE

3569
02:06:34,502 --> 02:06:36,170
REALLY WORKED TO CHANGE THEIR HR

3570
02:06:36,170 --> 02:06:40,074
POLICIES WITHIN THEIR OWN

3571
02:06:40,074 --> 02:06:40,875
UNIVERSITIES WITH BARRIERS TO

3572
02:06:40,875 --> 02:06:42,076
HIRING PEOPLE WITH LIVED

3573
02:06:42,076 --> 02:06:44,045
EXPERIENCE, WITH SUBSTANCE USE

3574
02:06:44,045 --> 02:06:46,113
DISORDER OR, IN PARTICULAR,

3575
02:06:46,113 --> 02:06:47,448
CRIMINAL JUSTICE INVOLVEMENT.

3576
02:06:47,448 --> 02:06:49,083
IN FACT, ONE OF OUR PARTER INS

3577
02:06:49,083 --> 02:06:51,252
WAS EVEN RECENTLY A PARTNER WHO

3578
02:06:51,252 --> 02:06:53,654
HAS A -- WHO LEADS A MAJOR

3579
02:06:53,654 --> 02:06:55,523
ORGANIZATION BUT HAS A HISTORY

3580
02:06:55,523 --> 02:06:57,792
OF JUSTICE INVOLVEMENT WAS NAMED

3581
02:06:57,792 --> 02:06:59,794
AS FACULTY AT YALE.

3582
02:06:59,794 --> 02:07:02,296
I THINK REALLY SIGNALING THAT

3583
02:07:02,296 --> 02:07:03,497
THERE IS MUCH MORE PROMISING

3584
02:07:03,497 --> 02:07:09,637
WORK TO COME IN THAT REGARD.

3585
02:07:09,637 --> 02:07:13,908
I WANT TO TURN TO TALKING ABOUT

3586
02:07:13,908 --> 02:07:15,977
OUR EFFORTS AROUND BUILDING

3587
02:07:15,977 --> 02:07:17,078
CAPACITY, FOUR DIFFERENT

3588
02:07:17,078 --> 02:07:18,279
ELEMENTS THE WAY WE'VE

3589
02:07:18,279 --> 02:07:20,247
STRUCTURED THE NETWORK, ONE IS A

3590
02:07:20,247 --> 02:07:22,316
TRAINING PROGRAM CALLED THE LEAP

3591
02:07:22,316 --> 02:07:23,084
INVESTIGATOR PROGRAM.

3592
02:07:23,084 --> 02:07:25,186
WE'VE GOT A SMALL GRANTS PROGRAM

3593
02:07:25,186 --> 02:07:27,455
WE CALL THE JCOIN RAPID

3594
02:07:27,455 --> 02:07:29,123
INNOVATION GRANTS, ON-DEMAND

3595
02:07:29,123 --> 02:07:30,124
TECHNICAL ASSISTANCE PROGRAM,

3596
02:07:30,124 --> 02:07:31,692
AND NUMEROUS COURSES, WEBINARS

3597
02:07:31,692 --> 02:07:32,493
AND PODCASTS.

3598
02:07:32,493 --> 02:07:34,028
SO I'LL GIVE YOU A LITTLE BIT OF

3599
02:07:34,028 --> 02:07:36,964
DETAIL ON EACH OF THESE.

3600
02:07:36,964 --> 02:07:38,299
THESE FACES HERE ARE ALL

3601
02:07:38,299 --> 02:07:39,734
PARTICIPANTS WHO'VE BEEN PART OF

3602
02:07:39,734 --> 02:07:42,803
OUR LEARNING EXPERIENCES TO

3603
02:07:42,803 --> 02:07:44,972
ADVANCE PRACTICE SCHOLARS AND

3604
02:07:44,972 --> 02:07:45,473
INVESTIGATORS PROGRAM.

3605
02:07:45,473 --> 02:07:48,809
WE'VE HAD 90 TRAINEES SO FAR.

3606
02:07:48,809 --> 02:07:50,544
WE BUILT BASICALLY AN R25 INTO

3607
02:07:50,544 --> 02:07:53,381
OUR COORDINATION AND TRANSLATION

3608
02:07:53,381 --> 02:07:54,582
CENTER INFRASTRUCTURE.

3609
02:07:54,582 --> 02:07:59,220
AND THEY'VE REALLY DONE A GREAT

3610
02:07:59,220 --> 02:08:00,287
DEAL OF WORK WITH THIS AND I

3611
02:08:00,287 --> 02:08:01,288
THINK ARE BUILDING FOUNT DAITION

3612
02:08:01,288 --> 02:08:02,923
OF THE FUTURE OF THE FIELD.

3613
02:08:02,923 --> 02:08:04,458
SO I'M GOING TO TAKE YOU THROUGH

3614
02:08:04,458 --> 02:08:05,126
THE TWO DIFFERENT COMPONENTS OF

3615
02:08:05,126 --> 02:08:06,761
THIS PROGRAM.

3616
02:08:06,761 --> 02:08:08,162
THE FIRST COMPONENT IS REALLY

3617
02:08:08,162 --> 02:08:09,697
ABOUT FOLKS THAT ARE ON THE

3618
02:08:09,697 --> 02:08:11,999
VERGE OF LAUNCHING THEIR NIH

3619
02:08:11,999 --> 02:08:12,333
CAREER.

3620
02:08:12,333 --> 02:08:13,768
IT'S A TWO-YEAR PROGRAM.

3621
02:08:13,768 --> 02:08:16,604
AND IT PROVIDES INTENSIVE

3622
02:08:16,604 --> 02:08:17,805
MENTORING, GRANTSMANSHIP WORK,

3623
02:08:17,805 --> 02:08:19,106
FUNDS FOR PILOT WORK.

3624
02:08:19,106 --> 02:08:20,775
WE'VE HAD 24 PARTICIPANTS IN

3625
02:08:20,775 --> 02:08:22,510
THIS SO FAR, BUT REALLY TRIES TO

3626
02:08:22,510 --> 02:08:25,446
HELP SET THEM UP TO BE

3627
02:08:25,446 --> 02:08:29,884
INDEPENDENT INVESTIGATORS, AND

3628
02:08:29,884 --> 02:08:31,052
HAS BEEN QUITE SUCCESSFUL IN

3629
02:08:31,052 --> 02:08:31,252
THAT.

3630
02:08:31,252 --> 02:08:33,654
WE'VE HAD 11 NEW NIH OR CDC

3631
02:08:33,654 --> 02:08:35,089
AWARDS MADE TO PARTICIPANTS IN

3632
02:08:35,089 --> 02:08:36,791
THIS PROGRAM, EITHER DURING OR

3633
02:08:36,791 --> 02:08:39,593
AFTER THEIR PARTICIPATION IN THE

3634
02:08:39,593 --> 02:08:40,795
PROGRAM, LOTS MORE APPLICATIONS

3635
02:08:40,795 --> 02:08:41,362
IN THE PIPELINE.

3636
02:08:41,362 --> 02:08:43,731
BUT I THINK IMPORTANTLY, WHAT

3637
02:08:43,731 --> 02:08:44,865
THIS HAS HELPED TO DO IS

3638
02:08:44,865 --> 02:08:46,267
DIVERSIFY THE FUTURE OF THE

3639
02:08:46,267 --> 02:08:46,600
FIELD.

3640
02:08:46,600 --> 02:08:48,669
THIS IS DIVERSIFYING FROM A

3641
02:08:48,669 --> 02:08:51,305
GEOGRAPHIC PERSPECTIVE, FROM A

3642
02:08:51,305 --> 02:08:54,475
DISCIPLINARY PERSPECTIVE,

3643
02:08:54,475 --> 02:08:55,743
GENDER, UNDERREPRESENTED

3644
02:08:55,743 --> 02:08:58,079
MINORITY AND EVEN SORT OF -- WE

3645
02:08:58,079 --> 02:08:59,413
HAVE A THIRD OF THE PARTICIPANTS

3646
02:08:59,413 --> 02:09:01,248
HERE WHO ARE FIRST GENERATION

3647
02:09:01,248 --> 02:09:01,782
COLLEGE.

3648
02:09:01,782 --> 02:09:03,451
SO THESE ARE THE FACES I THINK

3649
02:09:03,451 --> 02:09:05,753
OF THE FUTURE OF THE FIELD, AND

3650
02:09:05,753 --> 02:09:08,055
WE'VE BEEN VERY EXCITED TO SEE

3651
02:09:08,055 --> 02:09:09,356
THEM PARTICIPATE IN THIS, BUT

3652
02:09:09,356 --> 02:09:10,558
THEY ALSO, WHEN THEY ARE

3653
02:09:10,558 --> 02:09:11,992
PARTICIPATING IN THIS PROGRAM,

3654
02:09:11,992 --> 02:09:14,095
THERE'S A SECOND PART OF THE

3655
02:09:14,095 --> 02:09:15,262
PROGRAM THAT ACTUALLY HAS MORE

3656
02:09:15,262 --> 02:09:15,830
PARTICIPANTS.

3657
02:09:15,830 --> 02:09:18,132
THIS HAS FOCUSED ON TWO

3658
02:09:18,132 --> 02:09:18,899
DIFFERENT SIDES OF THINGS.

3659
02:09:18,899 --> 02:09:22,937
ONE FOR PEOPLE WHO ARE LITTLE

3660
02:09:22,937 --> 02:09:25,005
BIT EARLIER STAGE, MAYBE

3661
02:09:25,005 --> 02:09:26,474
POSTDOCS OR DOCTORAL STUDENTS,

3662
02:09:26,474 --> 02:09:27,842
AS WELL AS PRACTITIONERS.

3663
02:09:27,842 --> 02:09:30,044
AND THIS ELEMENT, THE LEAP

3664
02:09:30,044 --> 02:09:31,245
SCHOLARS TRACK FOR THE PROGRAM

3665
02:09:31,245 --> 02:09:33,347
REALLY FOCUSES ON FOUNDATIONAL

3666
02:09:33,347 --> 02:09:35,249
TRAINING AND HOW TO CONDUCT,

3667
02:09:35,249 --> 02:09:41,756
INTERPRET OR APPLY RESEARCH.

3668
02:09:41,756 --> 02:09:41,922
 IN

3669
02:09:41,922 --> 02:09:43,190
JUSTICE SETTINGS.

3670
02:09:43,190 --> 02:09:45,392
WE'VE HAD 66 PARTICIPANTS SO

3671
02:09:45,392 --> 02:09:46,927
FAR, FROM A VARIETY OF

3672
02:09:46,927 --> 02:09:47,728
DISCIPLINARY PERSPECTIVES.

3673
02:09:47,728 --> 02:09:49,563
IN CONTRAST, THIS IS A SHORTER

3674
02:09:49,563 --> 02:09:51,098
PROGRAM, JUST ONE YEAR, AND THE

3675
02:09:51,098 --> 02:09:52,500
PARTICIPANTS HAVE ENJOYED IT SO

3676
02:09:52,500 --> 02:09:54,268
MUCH, THEY'VE REQUESTED AN

3677
02:09:54,268 --> 02:09:56,270
ALUMNI PROGRAM, WHICH THEY'VE

3678
02:09:56,270 --> 02:09:56,704
LAUNCHED.

3679
02:09:56,704 --> 02:10:00,407
AGAIN, THIS IS CREATING NICE

3680
02:10:00,407 --> 02:10:03,944
GEOGRAPHIC DIVERSITY, GENDER,

3681
02:10:03,944 --> 02:10:05,513
FROM PEOPLE WHO ARE THE FIRST IN

3682
02:10:05,513 --> 02:10:07,081
THEIR FAMILY TO GO TO COLLEGE,

3683
02:10:07,081 --> 02:10:08,983
AND I KNOW THIS MAKES THIS SLIDE

3684
02:10:08,983 --> 02:10:10,518
BUSY, BUT WHAT I WANT TO

3685
02:10:10,518 --> 02:10:11,519
EMPHASIZE HERE IS WE'RE REALLY

3686
02:10:11,519 --> 02:10:12,820
PULLING FROM PEOPLE THAT ARE

3687
02:10:12,820 --> 02:10:14,388
COMING FROM DIFFERENT KINDS OF

3688
02:10:14,388 --> 02:10:15,689
BACKGROUNDS THAN WHAT WE

3689
02:10:15,689 --> 02:10:17,324
TRADITIONALLY SEE IN NIH

3690
02:10:17,324 --> 02:10:17,758
RESEARCH.

3691
02:10:17,758 --> 02:10:19,827
YOU SEE IN TERMS OF OUR

3692
02:10:19,827 --> 02:10:21,796
NON-ACADEMIC PARTNER -- OR

3693
02:10:21,796 --> 02:10:22,797
NON-ACADEMIC AFFILIATIONS OF

3694
02:10:22,797 --> 02:10:24,331
PARTICIPANTS, THESE ARE PEOPLE

3695
02:10:24,331 --> 02:10:25,933
COMING FROM SHERIFF'S

3696
02:10:25,933 --> 02:10:28,269
DEPARTMENTS AND TRIAL COURTS AND

3697
02:10:28,269 --> 02:10:29,370
RE-ENTRY RESOURCE CENTERS AND

3698
02:10:29,370 --> 02:10:33,808
TREATMENT ORGANIZATIONS, AND

3699
02:10:33,808 --> 02:10:34,842
FROM THE ACADEMIC SIDE, PEOPLE

3700
02:10:34,842 --> 02:10:36,343
COMING FROM NON-RESEARCH ONE

3701
02:10:36,343 --> 02:10:37,478
INSTITUTIONS OR INSTITUTIONS

3702
02:10:37,478 --> 02:10:41,148
THAT ARE OUTSIDE OF OUR JCOIN

3703
02:10:41,148 --> 02:10:42,016
NETWORK, SO WE'RE TRYING TO

3704
02:10:42,016 --> 02:10:43,317
SPREAD OUR REACH OUT INTO THE

3705
02:10:43,317 --> 02:10:44,852
FIELD AND GET A BROADER REACH

3706
02:10:44,852 --> 02:10:46,520
WITH THIS COMPONENT OF THE

3707
02:10:46,520 --> 02:10:49,790
TRAINING PROGRAM.

3708
02:10:49,790 --> 02:10:51,458
I WANT TO TURN NOW AND TALK A

3709
02:10:51,458 --> 02:10:52,092
LITTLE BIT ABOUT THE WORK WE'VE

3710
02:10:52,092 --> 02:10:56,130
DONE TO TRY TO FUND SMALL GRANTS

3711
02:10:56,130 --> 02:10:56,997
AND INNOVATION GRANTS.

3712
02:10:56,997 --> 02:10:59,967
THIS IS A PICTURE OF THE VAN

3713
02:10:59,967 --> 02:11:02,503
USED BY CODAC HEALTHCARE.

3714
02:11:02,503 --> 02:11:03,704
CODAC HEALTHCARE IS THE PARTNER

3715
02:11:03,704 --> 02:11:05,072
FOR BROWN UNIVERSITY'S RESEARCH

3716
02:11:05,072 --> 02:11:06,340
HUB.

3717
02:11:06,340 --> 02:11:08,843
AND CODAC IS LED BY LINDA

3718
02:11:08,843 --> 02:11:11,245
HURLEY, WHO IS THE CEO OF CODAC

3719
02:11:11,245 --> 02:11:12,780
AND IS ONE OF OUR JCOIN

3720
02:11:12,780 --> 02:11:15,950
PARTNERS.

3721
02:11:15,950 --> 02:11:17,585
BUT LINDA -- AS THEY'VE BEEN

3722
02:11:17,585 --> 02:11:21,288
ROLLING OUT THESE MOBILE

3723
02:11:21,288 --> 02:11:22,523
SERVICES, LINDA HAD LOTS OF

3724
02:11:22,523 --> 02:11:23,324
REALLY INTERESTING QUESTIONS

3725
02:11:23,324 --> 02:11:24,925
ABOUT HOW THINGS WERE WORKING

3726
02:11:24,925 --> 02:11:26,393
AND WANTED TO EVALUATE

3727
02:11:26,393 --> 02:11:27,561
COMPONENTS OF THIS, AND THOSE

3728
02:11:27,561 --> 02:11:28,195
QUESTIONS WERE DIFFERENT THAN

3729
02:11:28,195 --> 02:11:31,365
THE QUESTIONS THAT THE JCOIN

3730
02:11:31,365 --> 02:11:35,236
RESEARCH HUB WAS FUNDED TO DO.

3731
02:11:35,236 --> 02:11:36,437
SOMETIMES WE CAN EXPLORE

3732
02:11:36,437 --> 02:11:37,905
SUPPLEMENTS FOR THOSE IDEAS, BUT

3733
02:11:37,905 --> 02:11:39,707
THAT TO ME ENCAPSULATES ONE OF

3734
02:11:39,707 --> 02:11:40,608
THE CHALLENGES.

3735
02:11:40,608 --> 02:11:41,642
SOMETIMES WE'LL HEAR QUESTIONS

3736
02:11:41,642 --> 02:11:42,009
FROM THE FIELD.

3737
02:11:42,009 --> 02:11:44,345
I'M DOING THIS REALLY COOL

3738
02:11:44,345 --> 02:11:46,513
THING, HOW DO I SEE IF IT'S

3739
02:11:46,513 --> 02:11:47,915
WORKING, AND OFTEN WE DON'T HAVE

3740
02:11:47,915 --> 02:11:48,916
A GOOD ANSWER FOR THAT.

3741
02:11:48,916 --> 02:11:52,019
WE KNOW THAT THE NIH PROCESS CAN

3742
02:11:52,019 --> 02:11:53,754
BE VERY DIFFICULT TO NAVIGATE,

3743
02:11:53,754 --> 02:11:54,622
ESPECIALLY IF YOU DON'T HAVE

3744
02:11:54,622 --> 02:11:55,723
THAT EXPERIENCE OR YOU'RE NOT

3745
02:11:55,723 --> 02:11:58,259
COMING FROM A UNIVERSITY

3746
02:11:58,259 --> 02:11:59,894
EXPERIENCED WITH NIH GRANTS, AND

3747
02:11:59,894 --> 02:12:02,296
SO WE BUILT INTO JCOIN THE IDEA

3748
02:12:02,296 --> 02:12:04,732
OF THIS SMALL INNOVATION GRANT

3749
02:12:04,732 --> 02:12:06,200
PROGRAM.

3750
02:12:06,200 --> 02:12:07,935
THIS IS ADMINISTERED BY A

3751
02:12:07,935 --> 02:12:08,702
COORDINATION CENTER.

3752
02:12:08,702 --> 02:12:10,905
IT IS STILL VERY COMPETITIVE,

3753
02:12:10,905 --> 02:12:12,706
AND IT GOES THROUGH A RIGOROUS

3754
02:12:12,706 --> 02:12:13,841
REVIEW.

3755
02:12:13,841 --> 02:12:16,143
THE REVIEWERS ARE PART OF A

3756
02:12:16,143 --> 02:12:17,678
JCOIN -- JOINT JCOIN-WIDE

3757
02:12:17,678 --> 02:12:19,446
COMMITTEE THAT INCLUDES

3758
02:12:19,446 --> 02:12:20,214
PRACTITIONERS.

3759
02:12:20,214 --> 02:12:21,515
THE SIZE OF THESE AWARDS IS

3760
02:12:21,515 --> 02:12:23,851
ABOUT ON PAR WITH AN R03, BUT

3761
02:12:23,851 --> 02:12:25,185
THEY'RE MEANT TO REALLY, AGAIN,

3762
02:12:25,185 --> 02:12:26,453
EXPAND OUR REACH TO NEW IDEAS,

3763
02:12:26,453 --> 02:12:29,089
NEW PEOPLE, NEW SETTINGS, FEWER

3764
02:12:29,089 --> 02:12:30,291
BARRIERS TO ENTRY, SO THAT WE

3765
02:12:30,291 --> 02:12:33,193
CAN REALLY SEED THE MOST

3766
02:12:33,193 --> 02:12:35,462
INNOVATIVE IDEAS OUT IN THE

3767
02:12:35,462 --> 02:12:37,331
FIELD AND MAYBE GENERATE SOME

3768
02:12:37,331 --> 02:12:37,965
MOMENTUM THERE.

3769
02:12:37,965 --> 02:12:39,500
WE'VE MADE 13 OF THESE AWARDS

3770
02:12:39,500 --> 02:12:40,067
SINCE 2020.

3771
02:12:40,067 --> 02:12:42,136
IT HAS EXPANDED OUR JCOIN

3772
02:12:42,136 --> 02:12:43,337
PORTFOLIO IN NUMBER OF

3773
02:12:43,337 --> 02:12:44,571
MEANINGFUL WAYS, INCLUDING THE

3774
02:12:44,571 --> 02:12:45,339
KINDS OF PEOPLE THAT WE'RE ABLE

3775
02:12:45,339 --> 02:12:45,873
TO FUND.

3776
02:12:45,873 --> 02:12:47,641
SO WE WERE ABLE TO FUND LINDA TO

3777
02:12:47,641 --> 02:12:49,843
FOLLOW UP ON HER IDEA AS A

3778
02:12:49,843 --> 02:12:52,680
PRACTITIONERS, WO WE'VE HAD ONE

3779
02:12:52,680 --> 02:12:55,582
AWARD GO TO A LEAP PARTICIPANT,

3780
02:12:55,582 --> 02:12:57,751
FOUR TO RESEARCHERS COMING FROM

3781
02:12:57,751 --> 02:12:59,386
NON-RESEARCH 1 INSTITUTIONS, TWO

3782
02:12:59,386 --> 02:13:00,487
TO PEOPLE THAT ARE COMING FROM

3783
02:13:00,487 --> 02:13:02,589
VERY DIFFERENT DISCIPLINARY

3784
02:13:02,589 --> 02:13:03,657
BACKGROUNDS, AND WE'VE SEEN LOTS

3785
02:13:03,657 --> 02:13:05,192
OF REALLY GREAT IDEAS, AND

3786
02:13:05,192 --> 02:13:06,660
THOUGH IT'S NOT REALLY THE POINT

3787
02:13:06,660 --> 02:13:08,529
OF THIS PROGRAM TO LEAD TO

3788
02:13:08,529 --> 02:13:09,430
PUBLICATIONS OR NIH AWARDS,

3789
02:13:09,430 --> 02:13:10,497
THESE PROGRAMS HAVE DONE THAT AS

3790
02:13:10,497 --> 02:13:10,898
WELL.

3791
02:13:10,898 --> 02:13:12,800
SO WE'VE HAD FOUR PUBLICATIONS

3792
02:13:12,800 --> 02:13:15,202
COME OUT OF THESE SMALL GRANTS,

3793
02:13:15,202 --> 02:13:16,403
AS WELL AS ONE NIH AWARD, AND SO

3794
02:13:16,403 --> 02:13:17,738
WE'VE BEEN REALLY HAPPY WITH HOW

3795
02:13:17,738 --> 02:13:20,374
THAT HAS WORKED.

3796
02:13:20,374 --> 02:13:21,475
BUT WE KNOW EVEN WITH THAT,

3797
02:13:21,475 --> 02:13:24,878
THERE'S STILL BARRIERS TO ENTRY,

3798
02:13:24,878 --> 02:13:25,980
IT'S STILL A COMPETITIVE PROCESS

3799
02:13:25,980 --> 02:13:27,014
AND WE KNOW THAT OUR PARTNERS

3800
02:13:27,014 --> 02:13:29,049
ARE OUT THERE EVERY DAY STILL

3801
02:13:29,049 --> 02:13:30,584
TRYING TO DO THIS WORK, TRYING

3802
02:13:30,584 --> 02:13:31,585
TO FIGURE OUT IF WHAT THEY'RE

3803
02:13:31,585 --> 02:13:32,686
DOING IS WORKING.

3804
02:13:32,686 --> 02:13:34,088
THIS IS ANOTHER PICTURE THAT'S

3805
02:13:34,088 --> 02:13:35,723
COMING TO US COURTESY FROM

3806
02:13:35,723 --> 02:13:37,291
FRANKLIN COUNTY OF SORT OF THIS

3807
02:13:37,291 --> 02:13:40,461
PROCESS OF WHAT DELIVERING THESE

3808
02:13:40,461 --> 02:13:42,096
SERVICES IN A JAIL LOOKS LIKE.

3809
02:13:42,096 --> 02:13:43,230
AND WE'LL SOMETIMES GET CALL

3810
02:13:43,230 --> 02:13:46,834
FROM PEOPLE OUT THERE DOING

3811
02:13:46,834 --> 02:13:49,770
THIS, AND WE ALSO BUILT IN

3812
02:13:49,770 --> 02:13:50,604
ANTICIPATING THOSE KINDS OF

3813
02:13:50,604 --> 02:13:51,772
QUESTIONS IN A TRADITIONAL

3814
02:13:51,772 --> 02:13:52,873
STRUCTURE, WE DON'T OFTEN HAVE A

3815
02:13:52,873 --> 02:13:54,508
WAY TO RESPOND TO THAT, WE DON'T

3816
02:13:54,508 --> 02:13:57,578
HAVE THE RESOURCES TO DO THAT.

3817
02:13:57,578 --> 02:13:59,013
BUT WE BUILT INTO JCOIN THIS

3818
02:13:59,013 --> 02:14:00,314
IDEA OF TECHNICAL ASSISTANCE

3819
02:14:00,314 --> 02:14:00,547
PROGRAM.

3820
02:14:00,547 --> 02:14:04,184
WE WERE ABLE TO WORK WITH BJA

3821
02:14:04,184 --> 02:14:06,387
AND ESTABLISH AN MOU, THEY

3822
02:14:06,387 --> 02:14:07,588
PROVIDED US FUNDING TO DO THIS.

3823
02:14:07,588 --> 02:14:08,589
BUT IT BASICALLY BRIDGES THE

3824
02:14:08,589 --> 02:14:09,790
TYPE OF WORK THAT TYPICALLY

3825
02:14:09,790 --> 02:14:11,625
HAPPENS IN SAMHSA AND BJA

3826
02:14:11,625 --> 02:14:13,093
GRANTS, PROVIDING TRAINING AND

3827
02:14:13,093 --> 02:14:15,596
TECHNICAL ASSISTANCE TO BE ABLE

3828
02:14:15,596 --> 02:14:17,131
TO PROVIDE ON-DEMAND TECHNICAL

3829
02:14:17,131 --> 02:14:18,999
ASSISTANCE REALLY FOCUSED ON

3830
02:14:18,999 --> 02:14:20,000
RESEARCH AND EVALUATION NEEDS.

3831
02:14:20,000 --> 02:14:25,039
AND AGAIN, THIS I HAS PROVEN QUE

3832
02:14:25,039 --> 02:14:26,507
POPULAR OVER THE FIRST, I GUESS,

3833
02:14:26,507 --> 02:14:29,309
18 MONTHS OF OPERATION, WE HAD

3834
02:14:29,309 --> 02:14:30,978
93 TA REQUESTS THAT HAD COME

3835
02:14:30,978 --> 02:14:31,512
THROUGH.

3836
02:14:31,512 --> 02:14:32,813
WE'VE HAD MORE SINCE THEN, AND

3837
02:14:32,813 --> 02:14:34,214
THE KINDS OF REQUESTS THAT WE

3838
02:14:34,214 --> 02:14:36,116
GET ARE THINGS LIKE LOGIC MODELS

3839
02:14:36,116 --> 02:14:38,519
FOR PROGRAM EVALUATION, HELPING

3840
02:14:38,519 --> 02:14:41,155
AN AGENCY THINK THROUGH HOW TO

3841
02:14:41,155 --> 02:14:43,991
DO DATA-DRIVEN DECISION-MAKING,

3842
02:14:43,991 --> 02:14:47,828
WE HAVE A REALLY NICE EXAMPLE

3843
02:14:47,828 --> 02:14:49,129
FROM SOUTH DAKOTA WHERE THE WORK

3844
02:14:49,129 --> 02:14:51,765
THAT WAS DONE IN TRYING TO HELP

3845
02:14:51,765 --> 02:14:52,966
THE AGENCY IN TURN LED TO

3846
02:14:52,966 --> 02:14:55,169
ANOTHER TOOL THAT IS BEING PART

3847
02:14:55,169 --> 02:14:58,272
OF WHAT IS DISSEMINATED OUT TO

3848
02:14:58,272 --> 02:14:59,239
SUPPORT OTHERS AS THEY DO THEIR

3849
02:14:59,239 --> 02:14:59,573
WORK.

3850
02:14:59,573 --> 02:15:01,442
AND WHAT OUR TECHNICAL

3851
02:15:01,442 --> 02:15:02,876
ASSISTANCE GROUP DRAWS ON IS

3852
02:15:02,876 --> 02:15:03,510
REALLY A RICHNESS OF WHAT WE'VE

3853
02:15:03,510 --> 02:15:04,611
BEEN ABLE TO PUT INTO OUR

3854
02:15:04,611 --> 02:15:06,914
TRAINING AND ENGAGEMENT CENTER.

3855
02:15:06,914 --> 02:15:08,148
WE DEVELOPED A NUMBER OF

3856
02:15:08,148 --> 02:15:10,284
DIFFERENT RESOURCES, INCLUDING

3857
02:15:10,284 --> 02:15:11,652
FULLY DEVELOPED COURSES.

3858
02:15:11,652 --> 02:15:13,120
WE'VE GOT 50 COURSES.

3859
02:15:13,120 --> 02:15:14,154
MOST OF THESE COURSES ARE

3860
02:15:14,154 --> 02:15:14,922
SHORTER.

3861
02:15:14,922 --> 02:15:16,356
THEY MAY RANGE FROM 30 MINUTES

3862
02:15:16,356 --> 02:15:18,225
TO TWO HOURS IN CONTENT.

3863
02:15:18,225 --> 02:15:19,560
WE'VE GOT 20 MORE IN

3864
02:15:19,560 --> 02:15:20,427
DEVELOPMENT.

3865
02:15:20,427 --> 02:15:23,263
WE'VE HAD QUITE A BIT OF

3866
02:15:23,263 --> 02:15:24,798
ENGAGEMENT WITH 6400 COMPLETIONS

3867
02:15:24,798 --> 02:15:26,533
OF THESE COURSES WITH COMPLETION

3868
02:15:26,533 --> 02:15:28,735
RATES THAT EXCEED INDUSTRY

3869
02:15:28,735 --> 02:15:29,937
AVERAGES, BUT I THINK WHAT'S

3870
02:15:29,937 --> 02:15:31,805
SPECIAL ABOUT THIS IS THIS

3871
02:15:31,805 --> 02:15:33,907
APPROACH THAT HAS REALLY BEEN

3872
02:15:33,907 --> 02:15:35,109
SPEARHEADED BY THE ADDICTION

3873
02:15:35,109 --> 02:15:37,144
POLICY FORUM WORKING THROUGH --

3874
02:15:37,144 --> 02:15:38,912
AS PART OF THE COORDINATION AND

3875
02:15:38,912 --> 02:15:43,350
TRANSLATION CENTER THAT, THEY'VE

3876
02:15:43,350 --> 02:15:44,751
REALLY SPEARHEADED AN APPROACH

3877
02:15:44,751 --> 02:15:46,186
OF PARTNERING WITH KEY

3878
02:15:46,186 --> 02:15:47,321
ASSOCIATIONS, AND TAILORING THE

3879
02:15:47,321 --> 02:15:49,490
CONTENT TO THOSE ASSOCIATIONS.

3880
02:15:49,490 --> 02:15:50,824
SO ON THE TOP LEFT OF THE SCREEN

3881
02:15:50,824 --> 02:15:53,060
HERE, YOU SEE THERE'S AN MAT

3882
02:15:53,060 --> 02:15:54,161
COURSE FOR CORRECTIONAL LEADERS

3883
02:15:54,161 --> 02:15:55,129
THAT WAS DEVELOPED IN

3884
02:15:55,129 --> 02:15:55,996
CONJUNCTION WITH THE

3885
02:15:55,996 --> 02:15:57,331
CORRECTIONAL LEADERS OF AMERICA.

3886
02:15:57,331 --> 02:15:58,198
THESE ARE THE PEOPLE WHO ARE

3887
02:15:58,198 --> 02:16:00,934
EXECUTIVES OF PRISONS AND OTHER

3888
02:16:00,934 --> 02:16:03,670
SIMILAR CARS RAL SETTINGS.

3889
02:16:03,670 --> 02:16:05,105
AND THEN A SIMILAR COURSE BUT

3890
02:16:05,105 --> 02:16:06,206
THIS ONE DEVELOPED WITH IN

3891
02:16:06,206 --> 02:16:08,442
PARTNERSHIP WITH THE NATIONAL

3892
02:16:08,442 --> 02:16:09,510
CENTER FOR STATE COURTS AND

3893
02:16:09,510 --> 02:16:10,811
TARGETED TOWARDS JUDICIAL

3894
02:16:10,811 --> 02:16:12,913
LEADERS.

3895
02:16:12,913 --> 02:16:14,448
IN EACH OF THESE, WE HAVE EXTRA

3896
02:16:14,448 --> 02:16:16,783
CONTENT FROM THOSE PARTNERING

3897
02:16:16,783 --> 02:16:18,018
ORGANIZATIONS REALLY TAILORING

3898
02:16:18,018 --> 02:16:20,220
TO THEIR MEMBERSHIP AND

3899
02:16:20,220 --> 02:16:20,754
DISSEMINATING IT OUT.

3900
02:16:20,754 --> 02:16:22,856
I MENTIONED THE PODCAST EARLIER,

3901
02:16:22,856 --> 02:16:24,625
WE'VE GOT A NUMBER OF SHORT

3902
02:16:24,625 --> 02:16:26,160
MODULES, WE'VE HAD 18 WEBINARS

3903
02:16:26,160 --> 02:16:27,561
THAT HAVE BEEN QUITE POPULAR,

3904
02:16:27,561 --> 02:16:28,762
THE MOST POPULAR WAS ON

3905
02:16:28,762 --> 02:16:29,663
XYLAZINE, SO WE CONTINUE TO

3906
02:16:29,663 --> 02:16:30,998
BUILD THIS ROBUST SET OF

3907
02:16:30,998 --> 02:16:31,865
RESOURCES THAT ARE AVAILABLE FOR

3908
02:16:31,865 --> 02:16:35,335
OTHERS TO USE.

3909
02:16:35,335 --> 02:16:37,104
AND I'M VERY PLEASED TO SAY THAT

3910
02:16:37,104 --> 02:16:39,206
KOWN JCOIN AS WE COME TO THE END

3911
02:16:39,206 --> 02:16:41,275
OF A NORMAL FIVE-YEAR CYCLE, WE

3912
02:16:41,275 --> 02:16:44,344
HAVE RECEIVED SUPPORT TO MOVE

3913
02:16:44,344 --> 02:16:46,880
AHEAD WITH A SECOND ITERATION OF

3914
02:16:46,880 --> 02:16:49,183
JCOIN WE'RE CALLING INFORMALLY

3915
02:16:49,183 --> 02:16:50,951
JCOIN 2.0, AND THE FIRST STEP IN

3916
02:16:50,951 --> 02:16:53,687
THAT PROCESS IS TO CONTINUE OUR

3917
02:16:53,687 --> 02:16:54,321
SUPPORT INFRASTRUCTURE THAT

3918
02:16:54,321 --> 02:16:55,522
GIVES US A LOT OF THE THINGS I

3919
02:16:55,522 --> 02:16:58,592
JUST TALKED ABOUT, SMALL GRANTS

3920
02:16:58,592 --> 02:17:00,527
PROGRAM, THE SURVEYS, OUR DATA

3921
02:17:00,527 --> 02:17:02,029
INFRASTRUCTURE.

3922
02:17:02,029 --> 02:17:05,332
THOSE ARE RFAs THAT WERE

3923
02:17:05,332 --> 02:17:09,736
RELEARELEASED LAST YEAR AND WE E

3924
02:17:09,736 --> 02:17:11,271
TO BE ABLE TO I A NOUNS AWARDS

3925
02:17:11,271 --> 02:17:12,706
LATER THIS SUMMER FOR THAT

3926
02:17:12,706 --> 02:17:13,707
CONTINUITY OF INFRASTRUCTURE.

3927
02:17:13,707 --> 02:17:19,213
AND WE ALSO PUBLISHED LAST FALL

3928
02:17:19,213 --> 02:17:21,882
A NOTICE OF INTENT TO PUBLISH A

3929
02:17:21,882 --> 02:17:22,983
FUNDING OPPORTUNITY FOR HUBS TO

3930
02:17:22,983 --> 02:17:23,984
DO NEW RESEARCH.

3931
02:17:23,984 --> 02:17:25,586
THIS IS EXPECTED TO BE PUBLISHED

3932
02:17:25,586 --> 02:17:26,620
THIS SUMMER WITH APPLICATIONS

3933
02:17:26,620 --> 02:17:29,456
DUE IN WINTER OF 2025 AND THEN

3934
02:17:29,456 --> 02:17:30,557
AWARDS NEXT SUMMER.

3935
02:17:30,557 --> 02:17:32,426
AND JUST TO GIVE YOU A LITTLE

3936
02:17:32,426 --> 02:17:34,294
BIT OF A FLAVOR OF THE KINDS OF

3937
02:17:34,294 --> 02:17:37,698
THINKING THAT WE'RE DOING HERE

3938
02:17:37,698 --> 02:17:39,266
AND THAT IS DEMONSTRATED IN THAT

3939
02:17:39,266 --> 02:17:41,134
NOTICE, THIS IS THE IDEA OF A

3940
02:17:41,134 --> 02:17:44,938
SEQUENTIAL INTERCEPT MODEL, IF

3941
02:17:44,938 --> 02:17:46,807
YOU'RE NOT FAMILIAR WITH WORK IN

3942
02:17:46,807 --> 02:17:48,108
THE JUSTICE SETTING, THIS IS A

3943
02:17:48,108 --> 02:17:50,043
WAY TO SIMPLIFY A VERY COMPLEX

3944
02:17:50,043 --> 02:17:50,677
SYSTEM, THINKING ABOUT ALL THE

3945
02:17:50,677 --> 02:17:51,578
DIFFERENT POINTS OF INTERSECTION

3946
02:17:51,578 --> 02:17:52,879
FROM LAW ENFORCEMENT TO WHAT

3947
02:17:52,879 --> 02:17:54,314
HAPPENS AFTER SOMEONE IS

3948
02:17:54,314 --> 02:17:55,382
ARRESTED, TO WHAT THE COURTS DO,

3949
02:17:55,382 --> 02:17:56,950
WHAT HAPPENS IN JAILS AND

3950
02:17:56,950 --> 02:17:57,584
PRISONS, WHAT HAPPENS WHEN

3951
02:17:57,584 --> 02:17:59,486
PEOPLE ARE RETURNED TO THEIR

3952
02:17:59,486 --> 02:18:00,354
COMMUNITIES.

3953
02:18:00,354 --> 02:18:02,089
IN JCOIN, AND MOST OF OUR PRIOR

3954
02:18:02,089 --> 02:18:03,824
JUSTICE WORK AT NIDA IN GENERAL,

3955
02:18:03,824 --> 02:18:04,658
WE'VE FOCUSED REALLY ON THE

3956
02:18:04,658 --> 02:18:06,093
RIGHT-HAND SIDE OF THIS SLIDE,

3957
02:18:06,093 --> 02:18:07,394
AS WE LOOK FORWARD TO THE

3958
02:18:07,394 --> 02:18:09,263
FUTURE, WE REALLY HOPE WE CAN

3959
02:18:09,263 --> 02:18:10,797
START BUILDING THE EVIDENCE BASE

3960
02:18:10,797 --> 02:18:11,798
ALSO ON THE LEFT HAND OF THIS.

3961
02:18:11,798 --> 02:18:15,002
SO ALL THE PIECES CAN COME

3962
02:18:15,002 --> 02:18:15,902
TOGETHER.

3963
02:18:15,902 --> 02:18:17,304
AND AGAIN I'LL REFER YOU TO THE

3964
02:18:17,304 --> 02:18:18,405
NOTICE IF YOU WANT TO LEARN MORE

3965
02:18:18,405 --> 02:18:19,506
ABOUT THE KINDS OF THINGS WE'RE

3966
02:18:19,506 --> 02:18:21,508
THINKING ABOUT THAT REALLY,

3967
02:18:21,508 --> 02:18:23,377
AGAIN, THOSE EARLIER INTERCEPT

3968
02:18:23,377 --> 02:18:24,778
POINTS, BRINGING IN LIVED

3969
02:18:24,778 --> 02:18:26,647
EXPERIENCE, CONTINUING TO PUSH

3970
02:18:26,647 --> 02:18:29,416
ON IMPLEMENTATION SCIENCE,

3971
02:18:29,416 --> 02:18:30,284
UNDERSTANDING IMPACTS OF

3972
02:18:30,284 --> 02:18:32,619
CHANGING POLICY, CO-OCCURRING

3973
02:18:32,619 --> 02:18:33,720
CONDITIONS, AND LOTS OF OTHER

3974
02:18:33,720 --> 02:18:35,355
THINGS RELATED TO SPECIAL

3975
02:18:35,355 --> 02:18:36,890
POPULATIONS AND WAYS THAT WE GET

3976
02:18:36,890 --> 02:18:38,492
THESE TOOLS OUT THERE.

3977
02:18:38,492 --> 02:18:40,360
AND I'LL JUST START TO CLOSE

3978
02:18:40,360 --> 02:18:41,662
HERE BY SAYING THAT TOMORROW

3979
02:18:41,662 --> 02:18:44,631
WE'RE REALLY EXCITED, WE'VE BEEN

3980
02:18:44,631 --> 02:18:46,266
INVITED TO PROVIDE A PLENARY

3981
02:18:46,266 --> 02:18:47,601
SESSION AT THE HEAL SCIENTIFIC

3982
02:18:47,601 --> 02:18:48,702
MEETING.

3983
02:18:48,702 --> 02:18:50,237
YOU'LL HEAR -- AND WE GET TO

3984
02:18:50,237 --> 02:18:51,805
REALLY FEATURE OUR PARTNERS AND

3985
02:18:51,805 --> 02:18:52,973
THESE RELATIONSHIPS BETWEEN THE

3986
02:18:52,973 --> 02:18:53,874
INVESTIGATORS AND THEIR

3987
02:18:53,874 --> 02:18:54,308
PARTNERS.

3988
02:18:54,308 --> 02:18:56,510
WE'VE GOT A TEAM FROM KENTUCKY

3989
02:18:56,510 --> 02:18:57,077
COMING AS WELL AS THE

3990
02:18:57,077 --> 02:18:57,944
MASSACHUSETTS TEAM.

3991
02:18:57,944 --> 02:18:59,479
AND THEN LATER THIS SUMMER IN

3992
02:18:59,479 --> 02:19:01,281
JUNE, WE WILL HAVE A MEETING TO

3993
02:19:01,281 --> 02:19:02,482
REALLY CELEBRATE ALL OF THE

3994
02:19:02,482 --> 02:19:03,483
SCIENTIFIC FINDINGS THAT WILL BE

3995
02:19:03,483 --> 02:19:05,552
I THINK A 2 1/2 DAY MEETING HERE

3996
02:19:05,552 --> 02:19:06,987
IN NORTH BETHESDA AND AS SOON AS

3997
02:19:06,987 --> 02:19:08,188
WE HAVE MORE INFORMATION, I'M

3998
02:19:08,188 --> 02:19:10,057
HAPPY TO DISSEMINATE THAT.

3999
02:19:10,057 --> 02:19:12,726
AND SO I'LL JUST CLOSE BY THE QR

4000
02:19:12,726 --> 02:19:15,996
CODE CAN TAKE YOU TO

4001
02:19:15,996 --> 02:19:17,264
JCOINCTC.ORG, IT HAS ALL OF

4002
02:19:17,264 --> 02:19:17,631
THESE RESOURCES.

4003
02:19:17,631 --> 02:19:18,899
BUT I REALLY WANT TO THANK ALL

4004
02:19:18,899 --> 02:19:19,666
THE DIFFERENT PEOPLE THAT ARE

4005
02:19:19,666 --> 02:19:22,102
PART OF MAKING THIS WORK HAPPEN

4006
02:19:22,102 --> 02:19:24,171
BUT ESPECIALLY PEOPLE AND THEIR

4007
02:19:24,171 --> 02:19:25,505
FAMILIES AND THE WORKERS OUT

4008
02:19:25,505 --> 02:19:26,907
THERE TRYING TO GET HELP TO

4009
02:19:26,907 --> 02:19:28,575
PEOPLE WHO NEED IT.

4010
02:19:28,575 --> 02:19:29,343
SO THANK YOU FOR THE OPPORTUNITY

4011
02:19:29,343 --> 02:19:35,816
TO SHARE THIS WORK WITH YOU.

4012
02:19:35,816 --> 02:19:38,652
>> THANK YOU, IT SHA.

4013
02:19:38,652 --> 02:19:39,219
 TISHA.

4014
02:19:39,219 --> 02:19:40,587
THAT WAS FANTASTIC!

4015
02:19:40,587 --> 02:19:48,662
ARE THERE QUESTIONS?

4016
02:19:55,602 --> 02:19:57,304
I SEE MELISSA'S HANDS.

4017
02:19:57,304 --> 02:19:58,038
>> HI.

4018
02:19:58,038 --> 02:19:59,406
AS THE DOGS BEGIN TO BARK.

4019
02:19:59,406 --> 02:20:00,941
FIRST OF ALL, AS YOU WERE

4020
02:20:00,941 --> 02:20:02,909
SPEAKING, I WENT OVER THE

4021
02:20:02,909 --> 02:20:04,244
WEBSITE FOR JCOIN AND THE

4022
02:20:04,244 --> 02:20:05,112
RESEARCH CORE.

4023
02:20:05,112 --> 02:20:05,645
WOW!

4024
02:20:05,645 --> 02:20:06,446
IT'S INCREDIBLE!

4025
02:20:06,446 --> 02:20:10,617
THANK YOU FOR THE -- SOMETHING

4026
02:20:10,617 --> 02:20:11,151
IS COMING UP AT ME.

4027
02:20:11,151 --> 02:20:12,252
THANK YOU FOR SHARING, AND

4028
02:20:12,252 --> 02:20:14,688
YOU'VE BEEN SO BUSY.

4029
02:20:14,688 --> 02:20:16,156
AND I JUST WANTED TO OFFER A

4030
02:20:16,156 --> 02:20:17,524
COMMENT WHICH I THINK BLENDS THE

4031
02:20:17,524 --> 02:20:19,326
EARLIER COMMENTS WHEN WE WENT

4032
02:20:19,326 --> 02:20:20,961
OVER TIME WITH THIS TALK THAT

4033
02:20:20,961 --> 02:20:23,930
YOU GAVE, WHICH WAS EXCELLENT.

4034
02:20:23,930 --> 02:20:25,298
THE FIRST MAYBE FIVE OR SEVEN

4035
02:20:25,298 --> 02:20:27,100
MINUTES OF YOUR PRESENTATION

4036
02:20:27,100 --> 02:20:29,936
REALLY REMINDED US ABOUT THIS

4037
02:20:29,936 --> 02:20:31,405
PROCESS OF STRATIFICATION THAT

4038
02:20:31,405 --> 02:20:33,607
EVEN GETS PEOPLE TO HEALTHCARE

4039
02:20:33,607 --> 02:20:35,142
ENCOUNTERS OR TREATMENT

4040
02:20:35,142 --> 02:20:36,376
ENCOUNTERS IN THE FIRST PLACE,

4041
02:20:36,376 --> 02:20:37,811
AND YOU ADDED IN THIS COMPLEX

4042
02:20:37,811 --> 02:20:39,913
LAYER OF, YOU KNOW,

4043
02:20:39,913 --> 02:20:41,748
INCARCERATION, AND I THINK JUST

4044
02:20:41,748 --> 02:20:45,585
GOING BACK TO OUR PRIOR

4045
02:20:45,585 --> 02:20:47,254
CONVERSATION, REMINDING ALL OF

4046
02:20:47,254 --> 02:20:49,322
US THAT REALLY PROBABLY THE

4047
02:20:49,322 --> 02:20:50,190
HEALTHCARE SYSTEM ISN'T GOING TO

4048
02:20:50,190 --> 02:20:53,193
BE OUR ANSWER, AND TRAINING

4049
02:20:53,193 --> 02:20:54,594
PHYSICIANS IS IMPORTANT BUT IN

4050
02:20:54,594 --> 02:20:57,030
TERMS OF IMPACT, WE KNOW THAT

4051
02:20:57,030 --> 02:20:58,098
ACTUALLY THOSE INVESTMENTS TEND

4052
02:20:58,098 --> 02:21:00,200
TO WIDEN INEQUITIES IN THESE

4053
02:21:00,200 --> 02:21:01,735
HEALTH OUTCOMES, AND SO I JUST

4054
02:21:01,735 --> 02:21:03,503
WANT US TO BE AWARE OF THAT AND

4055
02:21:03,503 --> 02:21:05,739
HAS THAT AS AN ADDENDUM TO OUR

4056
02:21:05,739 --> 02:21:06,940
COMMENTARY PRIOR, ALL THANKS TO

4057
02:21:06,940 --> 02:21:08,942
YOU, TISHA, FOR KIND OF POINTING

4058
02:21:08,942 --> 02:21:09,309
THAT OUT TO US.

4059
02:21:09,309 --> 02:21:19,553
>> THANK YOU.

4060
02:21:25,058 --> 02:21:35,469
>> OTHER QUESTION,
COMMENTS?

4061
02:21:36,503 --> 02:21:38,205
WELL, I DON'T SEE ANY, SO AGAIN,

4062
02:21:38,205 --> 02:21:38,772
THANK YOU, TISHA.

4063
02:21:38,772 --> 02:21:42,943
IT REALLY IS AN AMAZING BODY OF

4064
02:21:42,943 --> 02:21:44,444
WORK, AND I THINK WE ARE ALL

4065
02:21:44,444 --> 02:21:47,881
REALLY APPRECIATIVE OF

4066
02:21:47,881 --> 02:21:49,316
EVERYTHING YOU'VE DONE SO FAR

4067
02:21:49,316 --> 02:21:50,283
AND LOOK FORWARD TO EVERYTHING

4068
02:21:50,283 --> 02:21:51,384
YOU'VE GOT PLANNED GOING

4069
02:21:51,384 --> 02:21:51,618
FORWARD.

4070
02:21:51,618 --> 02:21:55,222
>> WELL, THANK YOU FOR THE

4071
02:21:55,222 --> 02:21:56,089
SUPPORT AND THANK YOU TO MY TEAM

4072
02:21:56,089 --> 02:21:56,656
AGAIN.

4073
02:21:56,656 --> 02:21:57,991
REALLY AN INCREDIBLE TEAM I GET

4074
02:21:57,991 --> 02:21:59,993
TO WORK WITH, AND I APPRECIATE

4075
02:21:59,993 --> 02:22:01,495
NORA'S SUPPORT AND LEADERSHIP'S

4076
02:22:01,495 --> 02:22:01,895
SUPPORT AS WELL.

4077
02:22:01,895 --> 02:22:07,834
THANK YOU.

4078
02:22:07,834 --> 02:22:10,303
>> I'M GOING TO DO A MUCH
LESS

4079
02:22:10,303 --> 02:22:12,839
EXCITING PRESENTATION ON MERIT

4080
02:22:12,839 --> 02:22:15,242
AWARDS AND SORT OF FILL US IN

4081
02:22:15,242 --> 02:22:16,476
FROM WHERE WE LEFT OFF AND WHAT

4082
02:22:16,476 --> 02:22:17,777
WE'VE BEEN TALKING ABOUT AT NIDA

4083
02:22:17,777 --> 02:22:22,616
IN TERMS OF THE FUTURE OF THESE

4084
02:22:22,616 --> 02:22:23,617
AWARDS SO I'M GOING TO SHARE MY

4085
02:22:23,617 --> 02:22:33,760
SCREEN.

4086
02:22:35,295 --> 02:22:37,097
SORRY, I'M TRYING TO SWITCH IT.

4087
02:22:37,097 --> 02:22:47,374
BEFORE I SHARE.

4088
02:22:47,807 --> 02:22:57,584
OKAY.

4089
02:22:57,584 --> 02:22:58,718
I'M GOING TO STOP SHARING

4090
02:22:58,718 --> 02:22:59,886
BECAUSE I WANT TO MAKE IT A

4091
02:22:59,886 --> 02:23:10,196
SLIDE SHOW FIRST.

4092
02:23:19,673 --> 02:23:20,473
SORRY.

4093
02:23:20,473 --> 02:23:29,916
SORRY, GUYS.

4094
02:23:29,916 --> 02:23:31,318
ACTUALLY CAN I ASK YOU TO SHARE

4095
02:23:31,318 --> 02:23:37,891
MY SLIDES?

4096
02:23:37,891 --> 02:23:41,561
>> I DON'T HAVE THEM,
SUSAN.

4097
02:23:41,561 --> 02:23:42,095
>> RIGHT.

4098
02:23:42,095 --> 02:23:51,705
OKAY.

4099
02:23:51,705 --> 02:23:53,006
SO AGAIN, I'M GOING TO COME BACK

4100
02:23:53,006 --> 02:23:54,808
TO THIS DISCUSSION WHICH HAS

4101
02:23:54,808 --> 02:23:56,676
BEEN ONGOING NOW FOR A LITTLE

4102
02:23:56,676 --> 02:24:05,318
OVER A YEAR.

4103
02:24:05,318 --> 02:24:07,087
SO JUST AS A REMINDER, THE

4104
02:24:07,087 --> 02:24:11,257
CURRENT NIDA MERIT GUIDELINES

4105
02:24:11,257 --> 02:24:13,126
ARE -- THE FOCUS OF IT IS TO

4106
02:24:13,126 --> 02:24:15,095
RECOGNIZE INVESTIGATORS WHO HAVE

4107
02:24:15,095 --> 02:24:16,229
DEMONSTRATED OUTSTANDING

4108
02:24:16,229 --> 02:24:18,064
PRODUCTIVITY DURING THEIR

4109
02:24:18,064 --> 02:24:19,065
RESEARCH.

4110
02:24:19,065 --> 02:24:20,433
WITH THE IDEA THAT WE ANTICIPATE

4111
02:24:20,433 --> 02:24:22,702
THAT THEY WILL CONTINUE TO DO

4112
02:24:22,702 --> 02:24:25,105
SUCH STRONG WORK TRYING TO HAVE

4113
02:24:25,105 --> 02:24:27,741
WORK THAT HAS BEEN VERY

4114
02:24:27,741 --> 02:24:30,577
IMPACTFUL TO THE FIELD.

4115
02:24:30,577 --> 02:24:32,379
THESE ARE I A WARDS THAT ARE

4116
02:24:32,379 --> 02:24:34,881
GIVEN TO APPLICANTS WHO ARE

4117
02:24:34,881 --> 02:24:37,517
NOMINATED BY THE INSTITUTE

4118
02:24:37,517 --> 02:24:38,451
STAFF, AND THESE ARE PRESENTED

4119
02:24:38,451 --> 02:24:40,620
AS YOU KNOW TO COUNCIL FOR YOUR

4120
02:24:40,620 --> 02:24:41,955
CONSIDERATION, AND THE FINAL

4121
02:24:41,955 --> 02:24:43,356
SELECTIONS HAVE BEEN MADE BY THE

4122
02:24:43,356 --> 02:24:45,025
INSTITUTE DIRECTOR.

4123
02:24:45,025 --> 02:24:46,426
THE REQUIREMENTS THAT WE'VE HAD

4124
02:24:46,426 --> 02:24:48,128
FOR THESE AWARDS HAVE BEEN THAT

4125
02:24:48,128 --> 02:24:49,796
THE PERSON HAS PREVIOUSLY SERVED

4126
02:24:49,796 --> 02:24:52,966
AS A P.I. OF ONE OR MORE

4127
02:24:52,966 --> 02:24:55,735
INVESTIGATORS INITIATED PROJE

4128
02:24:55,735 --> 02:24:57,237
PROJECTS, THAT THEY HAVE AN

4129
02:24:57,237 --> 02:24:59,472
IMPRESSIVE RECORD OF SCIENTIFIC

4130
02:24:59,472 --> 02:25:01,141
ACHIEVEMENT, THAT THEIR

4131
02:25:01,141 --> 02:25:03,209
APPLICATION SCORED IN

4132
02:25:03,209 --> 02:25:05,779
5 PERCENTILE OR BETTER IN ONE OF

4133
02:25:05,779 --> 02:25:07,514
THE PREVIOUS TWO REVIEW CYCLES,

4134
02:25:07,514 --> 02:25:09,282
THAT IT AN UNAMENDED AM KAI AND

4135
02:25:09,282 --> 02:25:11,017
THAT THERE IS A TIME COMMITMENT

4136
02:25:11,017 --> 02:25:16,556
OF 15% OR MORE TO THE GRANT.

4137
02:25:16,556 --> 02:25:17,424
SO WHEN WE STARTED TO THINK

4138
02:25:17,424 --> 02:25:20,727
ABOUT THIS AND TALK ABOUT THIS

4139
02:25:20,727 --> 02:25:22,729
WITH OUR -- WITH COUNCIL AND

4140
02:25:22,729 --> 02:25:24,364
WITH THE WORK GROUP THAT WE

4141
02:25:24,364 --> 02:25:25,899
FORMED, WHICH I'LL COME TO IN A

4142
02:25:25,899 --> 02:25:28,334
MINUTE, WE ALSO LOOKED AT WHAT

4143
02:25:28,334 --> 02:25:30,336
OTHER ICs WERE DOING AROUND

4144
02:25:30,336 --> 02:25:32,839
NIH, AND I'VE HIGHLIGHTED FOR

4145
02:25:32,839 --> 02:25:34,607
YOU THE SIX OTHER ICs THAT ARE

4146
02:25:34,607 --> 02:25:37,477
STILL USING THE MERIT AWARD, OR

4147
02:25:37,477 --> 02:25:39,913
STILL USING IT IN THE SAME WAY

4148
02:25:39,913 --> 02:25:43,750
THAT I JUST DESCRIBED, THEREFORE

4149
02:25:43,750 --> 02:25:45,752
ESTABLISHED INVESTIGATORS WHO

4150
02:25:45,752 --> 02:25:47,387
HAVE A VERY IMPRESSIVE TRACK

4151
02:25:47,387 --> 02:25:47,620
RECORD.

4152
02:25:47,620 --> 02:25:49,789
AND YOU CAN SEE THAT FOR MANY OF

4153
02:25:49,789 --> 02:25:51,157
THE INSTITUTES, THEY EITHER

4154
02:25:51,157 --> 02:25:54,427
NEVER USED IT, THEY DISCONTINUED

4155
02:25:54,427 --> 02:25:56,062
IT, OR THERE ARE TWO OTHERS.

4156
02:25:56,062 --> 02:25:58,498
ONE IS FROM NCI, WHICH I WILL

4157
02:25:58,498 --> 02:25:59,599
SORT OF GIVE YOU THE BOTTOM LINE

4158
02:25:59,599 --> 02:26:02,001
OF WHAT I'M GOING TO SUGGEST,

4159
02:26:02,001 --> 02:26:03,303
BUT WE'RE ACTUALLY THINKING OF

4160
02:26:03,303 --> 02:26:05,972
TRYING TO MODEL OUR MERIT ON THE

4161
02:26:05,972 --> 02:26:07,073
STRATEGY THAT THEY'RE USING.

4162
02:26:07,073 --> 02:26:08,975
THEY NOW ONLY GIVE MERIT AWARDS

4163
02:26:08,975 --> 02:26:10,210
TO ESIs.

4164
02:26:10,210 --> 02:26:11,644
THESE ARE 7-YEAR AWARDS AND

4165
02:26:11,644 --> 02:26:13,947
THEY'RE DONE IN TWO PHASES, FOUR

4166
02:26:13,947 --> 02:26:16,483
YEARS AND THREE YEARS, I THINK.

4167
02:26:16,483 --> 02:26:19,119
AND NINDS ALSO HAS A 7-YEAR

4168
02:26:19,119 --> 02:26:21,955
AWARD WHICH IS SIMILAR TO THE

4169
02:26:21,955 --> 02:26:23,289
MERIT AWARD.

4170
02:26:23,289 --> 02:26:25,925
IT IS ALSO MOSTLY EXPERIENCED

4171
02:26:25,925 --> 02:26:30,964
INVESTIGATORS, ALTHOUGH THEY

4172
02:26:30,964 --> 02:26:33,266
COULD BE MID CAREER P.I.s, BUT

4173
02:26:33,266 --> 02:26:35,168
IT'S A SEVEN-YEAR AWARD.

4174
02:26:35,168 --> 02:26:38,805
ONE IS FIVE AND TWO, ONE IS FOUR

4175
02:26:38,805 --> 02:26:39,639
AND THREE.

4176
02:26:39,639 --> 02:26:40,607
ACTUALLY THE NINDS ONE IS FOUR

4177
02:26:40,607 --> 02:26:41,908
YEARS AND THREE YEARS.

4178
02:26:41,908 --> 02:26:43,209
SO THE OTHER INSTITUTES ARE NO

4179
02:26:43,209 --> 02:26:49,783
LONGER USING THIS MECHANISM.

4180
02:26:49,783 --> 02:26:51,551
IN MAY, WE FIRST BROUGHT THIS TO

4181
02:26:51,551 --> 02:26:52,886
YOUR ATTENTION WHEN WE PRESENTED

4182
02:26:52,886 --> 02:26:53,686
SOME HISTORICAL INFORMATION ON

4183
02:26:53,686 --> 02:26:58,224
THE MERIT AWARDS THAT WE HAVE

4184
02:26:58,224 --> 02:27:01,694
BEEN GIVING OVER THE YEARS.

4185
02:27:01,694 --> 02:27:03,096
AND HOW THE OTHER INSTITUTES USE

4186
02:27:03,096 --> 02:27:04,631
IT, WHICH IS THE SLIDE I JUST

4187
02:27:04,631 --> 02:27:05,165
SHOWED YOU.

4188
02:27:05,165 --> 02:27:06,266
THERE WERE A NUMBER OF CONCERNS

4189
02:27:06,266 --> 02:27:08,001
THAT WERE EXPRESSED, INCLUDING

4190
02:27:08,001 --> 02:27:09,269
THE FACT THAT THERE'S A LACK OF

4191
02:27:09,269 --> 02:27:11,104
GENDER AND RACIAL ETHNIC

4192
02:27:11,104 --> 02:27:12,238
DIVERSITY IN THE AWARDEES,

4193
02:27:12,238 --> 02:27:14,040
THERE'S A LACK OF DIVERSITY IN

4194
02:27:14,040 --> 02:27:16,176
THE SCIENTIFIC AREAS

4195
02:27:16,176 --> 02:27:17,811
REPRESENTED.

4196
02:27:17,811 --> 02:27:19,345
MOST OF THE MERIT AWARDS HAVE

4197
02:27:19,345 --> 02:27:23,016
GONE TO BASE  BASIC SCIENCE

4198
02:27:23,016 --> 02:27:23,349
RESEARCHERS.

4199
02:27:23,349 --> 02:27:25,752
AS I SAID, THE CRITERIA CAN ONLY

4200
02:27:25,752 --> 02:27:27,120
BE MET BY EXPERIENCED

4201
02:27:27,120 --> 02:27:28,288
INVESTIGATORS WHO ALREADY HAVE A

4202
02:27:28,288 --> 02:27:29,823
HISTORY OF OUTSTANDING

4203
02:27:29,823 --> 02:27:30,824
CONTRIBUTIONS AND WHO ARE LIKELY

4204
02:27:30,824 --> 02:27:33,593
TO CONTINUE TO GET FUNDED BASED

4205
02:27:33,593 --> 02:27:36,696
ON THEIR HISTORY AND THEIR

4206
02:27:36,696 --> 02:27:37,897
PERFORMANCE.

4207
02:27:37,897 --> 02:27:39,566
SO WE DECIDED TO CONVENE A

4208
02:27:39,566 --> 02:27:40,533
WORKING GROUP TO FURTHER DISCUSS

4209
02:27:40,533 --> 02:27:41,568
THE FUTURE OF THE MERIT AWARDS

4210
02:27:41,568 --> 02:27:43,870
AND TO PROVIDE SOME

4211
02:27:43,870 --> 02:27:50,543
RECOMMENDATIONS TO COUNCIL.

4212
02:27:50,543 --> 02:27:51,778
SO THESE ARE THE PEOPLE WHO WE

4213
02:27:51,778 --> 02:27:53,213
INVITED TO BE ON THE WORKING

4214
02:27:53,213 --> 02:27:55,849
GROUP.

4215
02:27:55,849 --> 02:27:57,050
THEY WERE ALSO INVITED TO JOIN

4216
02:27:57,050 --> 02:28:00,019
US FOR THIS DISCUSSION.

4217
02:28:00,019 --> 02:28:01,221
PAUL KENNY IS ON, I'M NOT SURE

4218
02:28:01,221 --> 02:28:02,455
IF ANY OTHER MEMBERS OF THE

4219
02:28:02,455 --> 02:28:06,759
GROUP THAT ARE NOT ALSO STILL ON

4220
02:28:06,759 --> 02:28:08,194
COUNCIL ARE ON, SO MELISSA IS

4221
02:28:08,194 --> 02:28:08,628
ON.

4222
02:28:08,628 --> 02:28:11,030
SO WE HAD A COUPLE OF -- WE HAD

4223
02:28:11,030 --> 02:28:13,266
A FEW MEETINGS AND WE HAD A

4224
02:28:13,266 --> 02:28:14,234
DISCUSSION ABOUT HOW THESE

4225
02:28:14,234 --> 02:28:20,039
AWARDS HAVE BEEN AWARDED IN THE

4226
02:28:20,039 --> 02:28:22,375
PAST, AND THE NEXT SLIDE SHOWS

4227
02:28:22,375 --> 02:28:23,676
THE RECOMMENDATIONS FROM THE

4228
02:28:23,676 --> 02:28:28,281
COUNCIL WORKING GROUP.

4229
02:28:28,281 --> 02:28:30,483
IN GENERAL, THEY WERE FACIAL

4230
02:28:30,483 --> 02:28:36,022
ABOUT CONTFAVORABLEABOUT CONTINE

4231
02:28:36,022 --> 02:28:37,457
CONSIDERATIONS.

4232
02:28:37,457 --> 02:28:39,726
THAT OTHER GRANT MECHANISMS BE

4233
02:28:39,726 --> 02:28:40,894
CONSIDERED, THAT EQUITY SHOULD

4234
02:28:40,894 --> 02:28:43,830
BE CONSIDERED, THEY SHOULD

4235
02:28:43,830 --> 02:28:45,498
PRIORITIZE RESEARCH FOCUSED ON

4236
02:28:45,498 --> 02:28:46,399
HEALTH EQUITY, AND THAT DURING

4237
02:28:46,399 --> 02:28:48,167
THE RENEWAL PHASE, WE REQUIRE

4238
02:28:48,167 --> 02:28:50,803
DEMONSTRATION OF PROMOTING OR

4239
02:28:50,803 --> 02:28:51,905
ADVANCE EQUITY IN THE FIELD.

4240
02:28:51,905 --> 02:28:53,139
FOR LESS EXPERIENCED

4241
02:28:53,139 --> 02:28:56,542
INVESTIGATORS, THERE COULD BE A

4242
02:28:56,542 --> 02:28:58,278
DEMONSTRATION OF AN

4243
02:28:58,278 --> 02:29:00,013
INCORPORATION OF DIVERSE

4244
02:29:00,013 --> 02:29:01,814
PERSPECTIVES BY REQUIRING A

4245
02:29:01,814 --> 02:29:02,682
PEDP, WHICH IS SOMETHING THAT

4246
02:29:02,682 --> 02:29:10,990
WE'RE USING NOW FOR A LOT OF OUR

4247
02:29:10,990 --> 02:29:12,091
FUNDING OPPORTUNITIES.

4248
02:29:12,091 --> 02:29:16,095
TO ALLOW FOR MULTI-P.I. AWARDS,

4249
02:29:16,095 --> 02:29:17,163
AND THERE WAS STILL A PREFERENCE

4250
02:29:17,163 --> 02:29:19,699
FOR THE 10 YEARS OF AWARDS BUT

4251
02:29:19,699 --> 02:29:20,967
DESPITE THE FACT THAT OTHER

4252
02:29:20,967 --> 02:29:22,802
ICs ARE OFFERING 7-YEAR

4253
02:29:22,802 --> 02:29:23,269
AWARDS.

4254
02:29:23,269 --> 02:29:26,539
SO NEXT SLIDE, PLEASE.

4255
02:29:26,539 --> 02:29:31,611
SO AT NIGH DA WE HAD NIDA, WE HE

4256
02:29:31,611 --> 02:29:32,979
FOLLOW-UP DISCUSSIONS WITH

4257
02:29:32,979 --> 02:29:34,747
SENIOR STAFF AND THROUGH EMAIL,

4258
02:29:34,747 --> 02:29:36,149
AND SOME OF THIS IS BASICALLY

4259
02:29:36,149 --> 02:29:38,017
WHERE WE KIND OF WOUND UP.

4260
02:29:38,017 --> 02:29:39,285
WE STARTED THINKING ABOUT WHAT

4261
02:29:39,285 --> 02:29:41,554
WE'RE TRYING TO ACHIEVE WITH

4262
02:29:41,554 --> 02:29:44,090
THIS.

4263
02:29:44,090 --> 02:29:45,391
SOME OF THE GOALS BROUGHT UP BY

4264
02:29:45,391 --> 02:29:47,627
THE WORK GROUP LIE ENHANCING THE

4265
02:29:47,627 --> 02:29:48,928
DIVERSITY OF THE INVESTIGATORS,

4266
02:29:48,928 --> 02:29:49,929
MAKING SURE THAT THERE'S

4267
02:29:49,929 --> 02:29:53,266
MENTORING OF INVESTIGATORS FROM

4268
02:29:53,266 --> 02:29:55,001
UNDERREPRESENTED GROUPS IN NIDA

4269
02:29:55,001 --> 02:29:56,569
RELEVANT AREA, ADVANCING EQUITY,

4270
02:29:56,569 --> 02:29:57,737
THESE ARE EXTREMELY IMPORTANT

4271
02:29:57,737 --> 02:29:59,672
FOR NIDA, AND THEY ARE VALUES

4272
02:29:59,672 --> 02:30:03,476
THAT WE ADHERE TO, BUT WE WERE

4273
02:30:03,476 --> 02:30:04,677
NOT SURE THAT THIS AWARD COULD

4274
02:30:04,677 --> 02:30:05,645
SORT OF ACHIEVE EVERYTHING THAT

4275
02:30:05,645 --> 02:30:07,380
WE WANTED.

4276
02:30:07,380 --> 02:30:08,548
AND THAT MAYBE THE MERIT AWARD

4277
02:30:08,548 --> 02:30:11,384
IS NOT THE IDEAL STRATEGY FOR

4278
02:30:11,384 --> 02:30:16,723
ACHIEVING THOSE ENDS.

4279
02:30:16,723 --> 02:30:17,757
HOWEVER, THE IDEA OF PROVIDING

4280
02:30:17,757 --> 02:30:19,125
STABLE FUNDING TO JUNIOR

4281
02:30:19,125 --> 02:30:20,126
INVESTIGATORS AT A CRITICAL TIME

4282
02:30:20,126 --> 02:30:21,194
IN THEIR CAREERS IS SOMETHING

4283
02:30:21,194 --> 02:30:23,162
THAT THE MERIT AWARD COULD DO.

4284
02:30:23,162 --> 02:30:26,032
AND THAT'S SORT OF WHERE WE

4285
02:30:26,032 --> 02:30:27,367
LANDED, THAT THAT MIGHT BE THE

4286
02:30:27,367 --> 02:30:30,103
BEST WAY FOR US TO USE THAT TYPE

4287
02:30:30,103 --> 02:30:33,473
OF AWARD GOING FORWARD.

4288
02:30:33,473 --> 02:30:34,640
SO THERE WAS STRONG SUPPORT FOR

4289
02:30:34,640 --> 02:30:36,609
AN ESI-FOCUSED MERIT AWARD,

4290
02:30:36,609 --> 02:30:38,845
THINKING ABOUT IT AS A 7-YEAR

4291
02:30:38,845 --> 02:30:41,247
AWARD, FIVE YEARS PLUS A

4292
02:30:41,247 --> 02:30:42,648
TWO-YEAR EXTENSION.

4293
02:30:42,648 --> 02:30:44,317
DISCUSSING SOME OF THE DIFFERENT

4294
02:30:44,317 --> 02:30:45,918
MECHANISMS, WE'VE KIND OF -- WE

4295
02:30:45,918 --> 02:30:47,086
LANDED ON THE IDEA THAT IT

4296
02:30:47,086 --> 02:30:51,357
SHOULD STILL BE FOR R01s ONLY.

4297
02:30:51,357 --> 02:30:52,592
SOME OF THE OTHER AWARDS WE HAVE

4298
02:30:52,592 --> 02:30:56,896
LIKE THE DP1 OR DP2 ARE ALREADY

4299
02:30:56,896 --> 02:30:58,431
CONSIDERED PRESTIGIOUS AWARDS

4300
02:30:58,431 --> 02:31:00,867
AND THEY'RE VERY MUCH

4301
02:31:00,867 --> 02:31:02,301
INVESTIGATOR-FOCUSED.

4302
02:31:02,301 --> 02:31:04,804
AND U AWARDS, THEY BY DEFINITION

4303
02:31:04,804 --> 02:31:06,172
INVOLVE SIGNIFICANT SCIENTIFIC

4304
02:31:06,172 --> 02:31:07,607
INPUT FROM NIDA STAFF OR OTHER

4305
02:31:07,607 --> 02:31:08,608
IC STAFF.

4306
02:31:08,608 --> 02:31:11,577
SO IT SEEMED LIKE THE R01 STILL

4307
02:31:11,577 --> 02:31:13,913
IS PROBABLY THE MOST -- THE BEST

4308
02:31:13,913 --> 02:31:15,548
AWARDS TO KIND OF STAY FOCUSED

4309
02:31:15,548 --> 02:31:17,850
ON FOR THESE MERITS.

4310
02:31:17,850 --> 02:31:22,221
WE WOULD CONSIDER MPI AWARDS IF

4311
02:31:22,221 --> 02:31:24,123
ALL THE P.I.s HAVE ESI STATUS

4312
02:31:24,123 --> 02:31:27,627
AT THE TIME OF THE AWARD.

4313
02:31:27,627 --> 02:31:30,630
AND WE DECIDED TO SUNSET THE

4314
02:31:30,630 --> 02:31:31,731
CURRENT MERIT AWARD, AND I'M

4315
02:31:31,731 --> 02:31:33,466
SURE WE CAN HAVE SOME DISCUSSION

4316
02:31:33,466 --> 02:31:36,002
ABOUT THIS AT THE END OF THIS

4317
02:31:36,002 --> 02:31:41,207
PRESENTATION.

4318
02:31:41,207 --> 02:31:44,377
THE ESI AWARD, WE WOULD WANT TO

4319
02:31:44,377 --> 02:31:47,013
BE EVALUATING IT AND WHETHER IT

4320
02:31:47,013 --> 02:31:48,314
BENEFITS AN INVESTIGATOR'S

4321
02:31:48,314 --> 02:31:49,382
CAREER TRAJECTORY WITH RESPECT

4322
02:31:49,382 --> 02:31:51,884
TO GETTING CONTINUED FUNDING,

4323
02:31:51,884 --> 02:31:54,120
PROMOTION OR TENURE, INNOVATION

4324
02:31:54,120 --> 02:31:56,989
AND RISK TAKING, AND SCIENTIFIC

4325
02:31:56,989 --> 02:32:04,864
AND PUBLIC HEALTH IMPACT.

4326
02:32:04,864 --> 02:32:06,532
SO THE INITIAL AWARD WOULD BE UP

4327
02:32:06,532 --> 02:32:07,233
TO FIVE YEARS, SIMILAR TO WHAT

4328
02:32:07,233 --> 02:32:07,767
WE HAVE NOW.

4329
02:32:07,767 --> 02:32:09,068
STAFF WILL BE SELECTING

4330
02:32:09,068 --> 02:32:11,704
APPLICATIONS FOR CONSIDERATION,

4331
02:32:11,704 --> 02:32:13,106
AND REQUEST PROVISIONAL APPROVAL

4332
02:32:13,106 --> 02:32:16,442
FROM OUR DIRECTOR.

4333
02:32:16,442 --> 02:32:17,543
THE DIVISION DIRECTOR WOULD BE

4334
02:32:17,543 --> 02:32:18,544
PRESENTING THE NOMINATION TO

4335
02:32:18,544 --> 02:32:19,912
COUNCIL FOR APPROVAL AND FOR

4336
02:32:19,912 --> 02:32:21,647
FINAL RECOMMENDATION TO THE NIDA

4337
02:32:21,647 --> 02:32:22,415
DIRECTOR.

4338
02:32:22,415 --> 02:32:24,550
AND THEN THE NIDA DIRECTOR WILL

4339
02:32:24,550 --> 02:32:25,751
OFFICIALLY SELECT THE MERIT

4340
02:32:25,751 --> 02:32:28,688
AWARDEE AND THEN BASE GRANT WILL

4341
02:32:28,688 --> 02:32:35,361
BE PROMOTED TO THE R37.

4342
02:32:35,361 --> 02:32:36,095
THE EXTENSION REQUEST PROCESS

4343
02:32:36,095 --> 02:32:37,497
WHICH WOULD AGAIN BE FOR JUST

4344
02:32:37,497 --> 02:32:38,931
TWO YEARS, THIS WOULD BEGIN

4345
02:32:38,931 --> 02:32:43,136
SIMILAR TO WHAT WE HAVE RIGHT

4346
02:32:43,136 --> 02:32:44,570
NOW FOR OUR CURRENT MERIT AWARD

4347
02:32:44,570 --> 02:32:45,771
FOR ESTABLISHED INVESTIGATORS.

4348
02:32:45,771 --> 02:32:47,540
THE P.O. WOULD REACH OUT ABOUT

4349
02:32:47,540 --> 02:32:49,008
1 1/2 YEARS PRIOR TO THE END OF

4350
02:32:49,008 --> 02:32:53,813
THE INITIAL AWARD PERIOD.

4351
02:32:53,813 --> 02:32:55,014
SORRY, THAT'S AN ERROR.

4352
02:32:55,014 --> 02:32:56,749
AND TO REQUEST THESE EXTENSION

4353
02:32:56,749 --> 02:32:57,717
MATERIALS.

4354
02:32:57,717 --> 02:32:59,018
AND THE MERIT AWARDS, WE'RE

4355
02:32:59,018 --> 02:33:01,420
TRYING TO MAKE THIS NOT TERRIBLY

4356
02:33:01,420 --> 02:33:02,822
BURDENSOME ON EITHER THE AWARDEE

4357
02:33:02,822 --> 02:33:05,224
OR THE NIDA STAFF SO THE REQUEST

4358
02:33:05,224 --> 02:33:07,393
WOULD BE FOR THE PROGRESS

4359
02:33:07,393 --> 02:33:08,594
REPORT, WHICH THE MERIT AWARDEE

4360
02:33:08,594 --> 02:33:09,729
WOULD HAVE TO BE WORKING ON

4361
02:33:09,729 --> 02:33:11,063
ANYWAY.

4362
02:33:11,063 --> 02:33:12,532
A FIVE-PAGE RESEARCH STRATEGY

4363
02:33:12,532 --> 02:33:15,101
FOR THE TWO-YEAR EXTENSION

4364
02:33:15,101 --> 02:33:15,701
PERIOD.

4365
02:33:15,701 --> 02:33:16,802
PROPOSED BUDGET FOR THAT

4366
02:33:16,802 --> 02:33:18,671
EXTENSION PERIOD, AND THEN THE

4367
02:33:18,671 --> 02:33:20,306
P.O. WOULD SUBMIT A ONE-PAGE

4368
02:33:20,306 --> 02:33:22,108
MEMO THAT SUMMARIZES WHAT THE

4369
02:33:22,108 --> 02:33:23,776
MERIT AWARDEE'S ACCOMPLISHMENTS

4370
02:33:23,776 --> 02:33:25,144
WERE IN THE FIRST PHASE OF THE

4371
02:33:25,144 --> 02:33:26,979
AWARD, PLANS FOR THE TWO-YEAR

4372
02:33:26,979 --> 02:33:30,950
EXTENSION, AND PROACHTNESS OF AS

4373
02:33:30,950 --> 02:33:32,151
OF THE EXTENSION.

4374
02:33:32,151 --> 02:33:33,119
THE DIVISIONS WILL REQUEST

4375
02:33:33,119 --> 02:33:34,554
APPROVAL FROM THE NIDA DIRECTOR

4376
02:33:34,554 --> 02:33:35,421
AND FROM COUNCIL.

4377
02:33:35,421 --> 02:33:36,856
WE WERE NOT PLANNING TO BRING

4378
02:33:36,856 --> 02:33:41,060
THESE BACK TO COUNCIL FOR --

4379
02:33:41,060 --> 02:33:43,162
WITH AN ACTUAL PRESENTATION

4380
02:33:43,162 --> 02:33:45,231
DURING THE CLOSED SESSION, BUT

4381
02:33:45,231 --> 02:33:46,199
THE INFORMATION WOULD BE

4382
02:33:46,199 --> 02:33:47,833
INCLUDED IN THE ELECTRONIC

4383
02:33:47,833 --> 02:33:51,103
COUNCIL BOOK, AND IF THIS IS

4384
02:33:51,103 --> 02:33:51,837
APPROVED, THEN THE EXTENSION

4385
02:33:51,837 --> 02:33:56,776
WOULD BE FUNDED.

4386
02:33:56,776 --> 02:33:58,277
SO AGAIN, WE WOULD WANT THIS TO

4387
02:33:58,277 --> 02:34:01,981
BE SOMETHING WHERE NIDA STAFF

4388
02:34:01,981 --> 02:34:02,982
IDENTIFY APPLICANTS,

4389
02:34:02,982 --> 02:34:04,116
INVESTIGATORS CANNOT APPLY FOR

4390
02:34:04,116 --> 02:34:04,550
IT.

4391
02:34:04,550 --> 02:34:06,519
WE WOULD WANT THEM TO HAVE ESI

4392
02:34:06,519 --> 02:34:09,689
STATUS AT THE TIME OF THE AWARD

4393
02:34:09,689 --> 02:34:11,591
SO IT WOULD HAVE TO BE THEIR

4394
02:34:11,591 --> 02:34:13,259
FIRST R01 AWARD AND THEY WOULD

4395
02:34:13,259 --> 02:34:16,996
HAVE TO HAVE ESI STATUS.

4396
02:34:16,996 --> 02:34:18,331
WE DECIDED, AND THIS WAS BASED

4397
02:34:18,331 --> 02:34:21,267
ON LOOKING AT THE DATA FROM PAST

4398
02:34:21,267 --> 02:34:23,402
YEARS, TO SEE IF WE COULD GET

4399
02:34:23,402 --> 02:34:24,604
SORT OF ENOUGH PEOPLE WHO WOULD

4400
02:34:24,604 --> 02:34:26,405
MEET THE TYPES OF QUALIFICATIONS

4401
02:34:26,405 --> 02:34:28,107
THAT WE WOULD BE LOOKING FOR,

4402
02:34:28,107 --> 02:34:30,276
AND WE KIND OF CAME UP WITH A

4403
02:34:30,276 --> 02:34:33,112
GENERAL IDEA OF HAVING

4404
02:34:33,112 --> 02:34:34,981
R01 APPLICATION SCORING 24 OR

4405
02:34:34,981 --> 02:34:37,416
BETTER WHICH PUT THEM IN ABOUT

4406
02:34:37,416 --> 02:34:38,517
THE TENTH PERCENTILE, BUT WE

4407
02:34:38,517 --> 02:34:40,152
WOULD CONSIDER EXCEPTIONS WITH

4408
02:34:40,152 --> 02:34:42,221
STRONG JUSTIFICATION, SO

4409
02:34:42,221 --> 02:34:43,623
DIVISION DIRECTORS OR THE

4410
02:34:43,623 --> 02:34:44,390
DIVISION STAFF COULD IDENTIFY

4411
02:34:44,390 --> 02:34:46,125
PEOPLE WHO MIGHT BE A LITTLE BIT

4412
02:34:46,125 --> 02:34:51,163
OUTSIDE OF THOSE DRY T CRITERIAA

4413
02:34:51,163 --> 02:34:52,898
MAKE A CASE WHY THEY SHOULD BE

4414
02:34:52,898 --> 02:34:54,200
CONSIDERED FOR THIS AWARD.

4415
02:34:54,200 --> 02:34:55,635
WE ALSO WOULD CONSIDER MPI

4416
02:34:55,635 --> 02:34:57,470
AWARDS IF ALL THE P.I.s HAVE

4417
02:34:57,470 --> 02:35:02,408
ESI STATUS.

4418
02:35:02,408 --> 02:35:03,809
SO WE'VE NOT DECIDED ON WHAT WE

4419
02:35:03,809 --> 02:35:04,910
WOULD CALL THE AWARD.

4420
02:35:04,910 --> 02:35:06,212
IT COULD STILL BE CALLED THE

4421
02:35:06,212 --> 02:35:09,782
MERIT AWARD, IT COULD BE CALLED

4422
02:35:09,782 --> 02:35:11,417
MERIT ESI AWARD BUT WE ARE ALSO

4423
02:35:11,417 --> 02:35:12,618
OPEN TO OTHER IDEAS.

4424
02:35:12,618 --> 02:35:14,220
AND YOU CAN STOP SHARING MY

4425
02:35:14,220 --> 02:35:19,125
SLIDES NOW.

4426
02:35:19,125 --> 02:35:20,359
AND WE CAN OPEN THIS UP FOR

4427
02:35:20,359 --> 02:35:30,569
DISCUSSION.

4428
02:35:37,043 --> 02:35:38,611
PAUL, DID YOU HAVE ANY THOUGHTS

4429
02:35:38,611 --> 02:35:39,445
SINCE YOU JOINED US?

4430
02:35:39,445 --> 02:35:40,746
I APPRECIATE YOU JOINING US.

4431
02:35:40,746 --> 02:35:42,615
YOU WERE ON THE WORKING GROUP.

4432
02:35:42,615 --> 02:35:45,418
>> NO, SUSAN, NOT
SPECIFIC.

4433
02:35:45,418 --> 02:35:46,719
I JUST WANTED TO THANK YOU FOR

4434
02:35:46,719 --> 02:35:48,387
ALL THE HARD WORK I KNOW YOU PUT

4435
02:35:48,387 --> 02:35:49,789
IN, YOUR TEAM PUT IN IN THE

4436
02:35:49,789 --> 02:35:50,089
BACKGROUND.

4437
02:35:50,089 --> 02:35:51,724
I THINK IT LANDED IN A REALLY

4438
02:35:51,724 --> 02:35:52,358
GOOD SPOT.

4439
02:35:52,358 --> 02:35:53,693
I GUESS IF THERE WAS ONE THING,

4440
02:35:53,693 --> 02:35:55,728
IT WOULD BE NICE TO SEE -- IT'S

4441
02:35:55,728 --> 02:35:58,798
A WAY OF TRACKING IMPACT, TO

4442
02:35:58,798 --> 02:36:01,167
SHOW THAT THOSE WHO ARE AWARDED,

4443
02:36:01,167 --> 02:36:01,934
WHATEVER THE NEW MERIT AWARD

4444
02:36:01,934 --> 02:36:04,537
ENDS UP BEING CALLED, WHAT KIND

4445
02:36:04,537 --> 02:36:05,638
OF CAREER BOOST THEY GET, JUST

4446
02:36:05,638 --> 02:36:07,373
TO REALLY SUPPORT THIS AS A

4447
02:36:07,373 --> 02:36:09,642
MECHANISM TO MAKE SURE IT'S KIND

4448
02:36:09,642 --> 02:36:10,843
OF WORTH EVERYONE'S WHILE.

4449
02:36:10,843 --> 02:36:12,378
I DON'T KNOW HOW YOU TRACK WITH

4450
02:36:12,378 --> 02:36:14,847
THOSE METRICS, BUT IT MIGHT BE

4451
02:36:14,847 --> 02:36:16,148
GOOD TO GIVE THAT SOME THOUGHT,

4452
02:36:16,148 --> 02:36:17,616
JUST TO SHOW IT'S WORKING.

4453
02:36:17,616 --> 02:36:18,951
>> YEAH, I THINK WE NEED
TO

4454
02:36:18,951 --> 02:36:20,953
THINK ABOUT IT BECAUSE I'M NOT

4455
02:36:20,953 --> 02:36:22,355
SURE WHO THE COMPARISON GROUP

4456
02:36:22,355 --> 02:36:23,789
WOULD BE, AND SO I THINK THAT'S

4457
02:36:23,789 --> 02:36:25,491
WHAT WE'LL HAVE TO REALLY THINK

4458
02:36:25,491 --> 02:36:26,459
ABOUT.

4459
02:36:26,459 --> 02:36:27,460
BUT I AGREE, IF WE'RE GOING TO

4460
02:36:27,460 --> 02:36:29,028
BE USING THIS AWARD AND WE WANT

4461
02:36:29,028 --> 02:36:30,029
TO USE THIS TO HELP PEOPLE THAT

4462
02:36:30,029 --> 02:36:31,564
ARE GETTING STARTED IN THEIR

4463
02:36:31,564 --> 02:36:33,532
CAREER, THEN WE WANT TO MAKE

4464
02:36:33,532 --> 02:36:43,242
SURE THAT IT'S DOING THAT.

4465
02:36:43,242 --> 02:36:43,676
ANNA ROSE?

4466
02:36:43,676 --> 02:36:44,777
YOU'RE MUTED.

4467
02:36:44,777 --> 02:36:47,113
>> SO IT'S BASICALLY
OFFERING A

4468
02:36:47,113 --> 02:36:47,980
TWO-YEAR EXTENSION TO SOMEONE

4469
02:36:47,980 --> 02:36:51,951
WHO HAD A WELL-SCORED R01 WHO'S

4470
02:36:51,951 --> 02:36:55,321
AN EARLY STAGE INVESTIGATOR.

4471
02:36:55,321 --> 02:36:56,489
WOULD THERE BE AN ADVANTAGE TO

4472
02:36:56,489 --> 02:36:57,790
CALLING THAT AN AWARD OR WOULD

4473
02:36:57,790 --> 02:36:59,125
THERE BE AN ADVANTAGE TO SIMPLY

4474
02:36:59,125 --> 02:37:00,192
MAKING THAT KIND OF APPLICATION

4475
02:37:00,192 --> 02:37:02,561
FOR AN EXTENSION AVAILABLE TO

4476
02:37:02,561 --> 02:37:06,065
EARLY STAGE INVESTIGATOR THAT

4477
02:37:06,065 --> 02:37:08,701
ARE THREE YEARS INTO THEIR FIRST

4478
02:37:08,701 --> 02:37:12,171
R01?

4479
02:37:12,171 --> 02:37:13,339
I'M JUST ASKING.

4480
02:37:13,339 --> 02:37:15,975
I'M ON THE OWD SIDE LOOKING IN

4481
02:37:15,975 --> 02:37:18,978
HERE, BUT IT SOUNDS LIKE THE NET

4482
02:37:18,978 --> 02:37:20,279
BENEFIT IS TO GET AN EXTENSION.

4483
02:37:20,279 --> 02:37:24,250
>> THAT IS THE NET
BENEFIT.

4484
02:37:24,250 --> 02:37:25,751
I THINK PART OF THE THINKING,

4485
02:37:25,751 --> 02:37:29,789
AND PART OF THE REASON FOR HAV

4486
02:37:29,789 --> 02:37:32,425
HAVING THIS NOT BE AN AWARD

4487
02:37:32,425 --> 02:37:34,593
PEOPLE WOULD APPLY FOR BUT BE AN

4488
02:37:34,593 --> 02:37:37,329
AWARD WHERE STAFF ARE SELECTING

4489
02:37:37,329 --> 02:37:39,398
PEOPLE IS TO ACKNOWLEDGE THE

4490
02:37:39,398 --> 02:37:41,033
PERSON AND TO SORT OF GIVE --

4491
02:37:41,033 --> 02:37:42,234
HOPEFULLY GIVE THEIR CAREER A

4492
02:37:42,234 --> 02:37:44,937
BOOST BY PUTTING THEM IN THIS

4493
02:37:44,937 --> 02:37:45,938
OTHER CATEGORY.

4494
02:37:45,938 --> 02:37:47,239
ALSO BRINGING INFORMATION ABOUT

4495
02:37:47,239 --> 02:37:49,408
THEM TO COUNCIL.

4496
02:37:49,408 --> 02:37:53,279
SO I DON'T KNOW THAT WE -- WE

4497
02:37:53,279 --> 02:37:54,513
DIDN'T TALK ABOUT THE IDEA OF

4498
02:37:54,513 --> 02:37:56,916
MAKING THIS MORE OF AN OPEN CALL

4499
02:37:56,916 --> 02:38:04,857
FOR ALL ESIs TO BE ABLE TO GET

4500
02:38:04,857 --> 02:38:05,758
AN EXTENSION AND I DON'T THINK

4501
02:38:05,758 --> 02:38:06,926
WE WANT TO DO THAT AT THIS

4502
02:38:06,926 --> 02:38:08,227
POINT, BUT WE DID DISCUSS THE

4503
02:38:08,227 --> 02:38:09,328
IDEA OF WHETHER THIS SHOULD BE

4504
02:38:09,328 --> 02:38:11,163
AN AWARD THAT SOMEBODY COULD

4505
02:38:11,163 --> 02:38:13,232
APPLY FOR, APPLY FOR A

4506
02:38:13,232 --> 02:38:13,866
SEVEN-YEAR AWARD WHERE THEY

4507
02:38:13,866 --> 02:38:15,067
WOULD GET FIVE YEARS AND THEN

4508
02:38:15,067 --> 02:38:16,602
HAVE THE POSSIBILITY OF THE

4509
02:38:16,602 --> 02:38:17,570
TWO-YEAR EXTENSION VERSUS ONE

4510
02:38:17,570 --> 02:38:22,374
THAT WOULD BE SELECTED BY STAFF,

4511
02:38:22,374 --> 02:38:23,909
AND WE OPTED FOR IT BEING ONE

4512
02:38:23,909 --> 02:38:24,910
SELECTED BY STAFF ONLY BECAUSE

4513
02:38:24,910 --> 02:38:27,213
WE THOUGHT THAT THAT MIGHT GIVE

4514
02:38:27,213 --> 02:38:28,681
THEM A BIT OF ANED AD BOOST IN

4515
02:38:28,681 --> 02:38:34,587
THEIR CAREER TRAJECTORY.

4516
02:38:34,587 --> 02:38:35,754
NORA, DID YOU WANT TO SAY

4517
02:38:35,754 --> 02:38:36,021
SOMETHING?

4518
02:38:36,021 --> 02:38:37,623
>> NO, NO, NO, I WAS JUST

4519
02:38:37,623 --> 02:38:37,957
LISTENING.

4520
02:38:37,957 --> 02:38:39,058
I DIDN'T HAVE ANYTHING SPECIFIC

4521
02:38:39,058 --> 02:38:40,226
IN TERMS OF ACTUALLY I THINK

4522
02:38:40,226 --> 02:38:41,393
THAT THE OTHER CONSIDERATION

4523
02:38:41,393 --> 02:38:44,363
THAT CAME INTO PLAY IN OUR

4524
02:38:44,363 --> 02:38:47,833
DISCUSSIONS WAS HOW TOUGH IT HAS

4525
02:38:47,833 --> 02:38:50,102
BECOME TO ACTUALLY GET THE

4526
02:38:50,102 --> 02:38:51,537
GRANTS, AND PARTICULARLY FOR

4527
02:38:51,537 --> 02:38:55,140
YOUNG PEOPLE, NOT TO SUSTAIN

4528
02:38:55,140 --> 02:38:57,543
THEM, AND THAT'S WHY CONSIDERING

4529
02:38:57,543 --> 02:38:58,711
THAT WE ARE FORESEEING THAT

4530
02:38:58,711 --> 02:38:59,678
THERE'S NOT GOING TO BE

4531
02:38:59,678 --> 02:39:01,113
INCREASES IN FUNDING AND THERE

4532
02:39:01,113 --> 02:39:04,149
COULD BE SIGNIFICANT DECREASES,

4533
02:39:04,149 --> 02:39:06,819
WE WANT TO CREATE A VERY STRONG

4534
02:39:06,819 --> 02:39:10,089
MESSAGE THAT WE DO WANT TO

4535
02:39:10,089 --> 02:39:11,357
ENCOURAGE AND SUPPORT THE NEW

4536
02:39:11,357 --> 02:39:13,359
GENERATION OF SCIENTISTS.

4537
02:39:13,359 --> 02:39:17,062
THAT'S AN ASPECT THAT WAS QUITE

4538
02:39:17,062 --> 02:39:18,264
FUNDAMENTAL IN WHAT WE WERE

4539
02:39:18,264 --> 02:39:19,532
DOING, AND AT THE SAME TIME THAT

4540
02:39:19,532 --> 02:39:22,401
WE'RE COMMIT TODAY DIVERSITY,

4541
02:39:22,401 --> 02:39:27,973
GCOMMITTED TO DIVERSITY,PROVIDIG

4542
02:39:27,973 --> 02:39:29,341
THAT BREATHING SPACE TO

4543
02:39:29,341 --> 02:39:31,277
RESEARCHERS WHO ARE STARTING

4544
02:39:31,277 --> 02:39:32,678
THEIR CAREERS WOULD BE VERY

4545
02:39:32,678 --> 02:39:33,245
VALUABLE, AT THE SAME TIME

4546
02:39:33,245 --> 02:39:35,114
CREATING A MECHANISM THAT WOULD

4547
02:39:35,114 --> 02:39:36,582
ALSO RECOGNIZE THEM.

4548
02:39:36,582 --> 02:39:38,117
SO IT'S LIKE AN ACHIEVEMENT.

4549
02:39:38,117 --> 02:39:39,652
SO THAT WAS ALSO -- THAT ALSO

4550
02:39:39,652 --> 02:39:49,929
CAME INTO PLAY.

4551
02:39:57,536 --> 02:39:59,238
>> CAN I ASK A QUESTION?

4552
02:39:59,238 --> 02:40:00,873
CAN THE EXISTING MERIT AWARDS --

4553
02:40:00,873 --> 02:40:02,308
ARE THEY GOING TO BE STAYING AND

4554
02:40:02,308 --> 02:40:04,276
THEN BEING PHASED OUT, AND THIS

4555
02:40:04,276 --> 02:40:06,412
IS SORT OF AN OVERLAP HOW THIS

4556
02:40:06,412 --> 02:40:10,449
WILL BE PHASED IN OR HOW DO YOU

4557
02:40:10,449 --> 02:40:10,849
ENVISION THIS?

4558
02:40:10,849 --> 02:40:12,184
>> WE HAVEN'T BEEN GIVING
NEW

4559
02:40:12,184 --> 02:40:13,385
MERIT AWARDS FOR ABOUT -- WHEN

4560
02:40:13,385 --> 02:40:14,853
WE STARTED HAVING THIS

4561
02:40:14,853 --> 02:40:15,754
DISCUSSION, WE ALSO STOPPED

4562
02:40:15,754 --> 02:40:17,289
DOING NEW MERIT AWARDS.

4563
02:40:17,289 --> 02:40:18,624
SO THE IDEA WOULD BE THAT WE

4564
02:40:18,624 --> 02:40:20,125
WOULD BE PHASING IT OUT.

4565
02:40:20,125 --> 02:40:21,126
PEOPLE THAT ALREADY HAVE MERIT

4566
02:40:21,126 --> 02:40:22,094
AWARDS AND THAT ARE COMING UP

4567
02:40:22,094 --> 02:40:25,898
FOR EX-TENG EXTENSIONS, WE WOULD

4568
02:40:25,898 --> 02:40:27,967
CONTINUE THOSE EXTENSIONS, AND

4569
02:40:27,967 --> 02:40:29,068
THERE WERE A COUPLE TODAY THAT

4570
02:40:29,068 --> 02:40:30,469
WE HAD, THAT WE DISCUSSED

4571
02:40:30,469 --> 02:40:30,803
EARLIER.

4572
02:40:30,803 --> 02:40:32,972
SO THOSE WOULD FINISH OUT THE

4573
02:40:32,972 --> 02:40:34,506
COURSE, BUT WE WOULDN'T BE

4574
02:40:34,506 --> 02:40:37,009
GIVING NEW MERIT AWARDS TO

4575
02:40:37,009 --> 02:40:45,017
ESTABLISHED INVESTIGATORS.

4576
02:40:45,017 --> 02:40:46,952
>> I DON'T SEE ANY MORE
HANDS

4577
02:40:46,952 --> 02:40:49,722
RAISED, SUSAN.

4578
02:40:49,722 --> 02:40:51,423
>> I DON'T EITHER.

4579
02:40:51,423 --> 02:40:52,858
WELL, IF YOU HAVE THOUGHTS ON A

4580
02:40:52,858 --> 02:40:54,159
NAME, OTHERWISE WE CAN STILL

4581
02:40:54,159 --> 02:40:56,195
CALL IT THE MERIT AWARD FOR

4582
02:40:56,195 --> 02:40:59,031
ESIs OR MERIT ESI.

4583
02:40:59,031 --> 02:41:00,899
IF YOU HAVE ANY IDEAS OR ANY

4584
02:41:00,899 --> 02:41:02,368
CREATIVE SUGGESTIONS, SEND THEM

4585
02:41:02,368 --> 02:41:09,008
TO US.

4586
02:41:09,008 --> 02:41:13,445
>> I THINK -- WE HAVE 13

4587
02:41:13,445 --> 02:41:13,779
MINUTES.

4588
02:41:13,779 --> 02:41:17,182
DO YOU WANT TO START EARLY OR

4589
02:41:17,182 --> 02:41:18,317
DELAY UNTIL 3:45?

4590
02:41:18,317 --> 02:41:20,986
>> I WANT TO -- SEE IF
ANYBODY

4591
02:41:20,986 --> 02:41:21,754
WANTS TO CONTINUE THE

4592
02:41:21,754 --> 02:41:24,089
CONVERSATION WITH YOU THAT I CUT

4593
02:41:24,089 --> 02:41:24,990
OFF SINCE THERE WAS STILL -- IF

4594
02:41:24,990 --> 02:41:26,859
YOU DON'T MIND.

4595
02:41:26,859 --> 02:41:28,260
WOULD THAT BE OKAY WITH YOU?

4596
02:41:28,260 --> 02:41:29,862
>> OF COURSE.

4597
02:41:29,862 --> 02:41:30,262
ABSOLUTELY, YEAH.

4598
02:41:30,262 --> 02:41:33,265
>> OKAY.

4599
02:41:33,265 --> 02:41:35,567
SO I CUT OFF RAJITA, AND I'M NOT

4600
02:41:35,567 --> 02:41:38,671
SURE IF SHE'S --

4601
02:41:38,671 --> 02:41:40,339
>> HI, SUSAN.

4602
02:41:40,339 --> 02:41:41,006
I AM HERE.

4603
02:41:41,006 --> 02:41:42,541
I'M JUST ON AUDIO-ONLY NOW

4604
02:41:42,541 --> 02:41:44,610
BECAUSE I'M TRYING TO GET TO THE

4605
02:41:44,610 --> 02:41:45,678
HEAL MEETING.

4606
02:41:45,678 --> 02:41:47,112
BUT THANK YOU FOR OPENING IT UP.

4607
02:41:47,112 --> 02:41:49,548
I JUST WANTED TO FOLLOW BACK ALL

4608
02:41:49,548 --> 02:41:51,116
OF THE RICH DISCUSSION AROUND

4609
02:41:51,116 --> 02:41:55,154
THE THRESHOLD ISSUE AND MAKE A

4610
02:41:55,154 --> 02:41:56,155
COMMENT AND THEN ANOTHER

4611
02:41:56,155 --> 02:41:57,990
QUESTION THAT I WANTED TO RAISE.

4612
02:41:57,990 --> 02:42:01,493
THE COMMENT WAS -- AND NORA

4613
02:42:01,493 --> 02:42:03,429
REMEMBERS THIS, T.K. LEE HAD PUT

4614
02:42:03,429 --> 02:42:07,499
TOGETHER THE WORKING GROUP IN

4615
02:42:07,499 --> 02:42:08,667
THE LATE '90S TO COME UP WITH

4616
02:42:08,667 --> 02:42:09,968
HAZARDOUS AND NON-HAZARDOUS

4617
02:42:09,968 --> 02:42:12,705
DRINKING LEVEL, I BELIEVE, AND

4618
02:42:12,705 --> 02:42:14,440
THEN THAT GOT TRANSLATED INTO --

4619
02:42:14,440 --> 02:42:19,278
AS WE ALL KNOW, THE U.S. DIETARY

4620
02:42:19,278 --> 02:42:20,379
GUIDELINES HAVE HAZARDOUS

4621
02:42:20,379 --> 02:42:23,148
DRINKING LEVELS, THE CDC HAS

4622
02:42:23,148 --> 02:42:24,283
BINGE DRINKING LEVELS AND IT'S

4623
02:42:24,283 --> 02:42:25,851
BEING USED IN A LOT OF DIFFERENT

4624
02:42:25,851 --> 02:42:27,052
WAYS, AND I THINK THOSE

4625
02:42:27,052 --> 02:42:31,023
THRESHOLDS LED TO THEN THE

4626
02:42:31,023 --> 02:42:33,592
GROWTH OF RESEARCH FOR

4627
02:42:33,592 --> 02:42:36,662
IDENTIFYING BIOMARKERS, WHICH

4628
02:42:36,662 --> 02:42:37,863
WAS CHARLIE'S POINT.

4629
02:42:37,863 --> 02:42:39,698
SO I JUST THINK IT WOULD BE

4630
02:42:39,698 --> 02:42:43,202
REALLY AMAZING AND SUCH A GOOD

4631
02:42:43,202 --> 02:42:44,169
DOVETAIL OF WORK THAT YOU HAVE

4632
02:42:44,169 --> 02:42:45,671
ALREADY DONE WITH THE STANDARD

4633
02:42:45,671 --> 02:42:47,539
UNITS FOR CANNABIS.

4634
02:42:47,539 --> 02:42:49,508
SO THAT'S JUST A COMMENT.

4635
02:42:49,508 --> 02:42:51,143
THE OTHER THING I JUST WANTED TO

4636
02:42:51,143 --> 02:42:55,180
ASK ABOUT WAS RFAs AND THE ONE

4637
02:42:55,180 --> 02:42:57,483
TIME RFAs VERSUS RFAs THAT

4638
02:42:57,483 --> 02:42:58,884
ARE OPEN MULTIPLE TIMES.

4639
02:42:58,884 --> 02:43:01,987
THE REASON -- AND THINKING OF

4640
02:43:01,987 --> 02:43:03,088
ESIs AND ALSO OTHER

4641
02:43:03,088 --> 02:43:05,591
INVESTIGATORS WHEN IT'S A

4642
02:43:05,591 --> 02:43:07,960
SINGLE, YOU KNOW, SUBMISSION

4643
02:43:07,960 --> 02:43:09,261
RFA, THINGS ARE ON THE CUSP,

4644
02:43:09,261 --> 02:43:10,696
THINGS THAT DON'T GET FUNDED,

4645
02:43:10,696 --> 02:43:12,564
THERE ARE GOOD IDEAS THAT -- I

4646
02:43:12,564 --> 02:43:13,565
KNOW THEY CAN GO INTO THE

4647
02:43:13,565 --> 02:43:15,567
REGULAR POOL, BUT IF IT'S A

4648
02:43:15,567 --> 02:43:18,103
PRIORITY AREA, I WONDER IF

4649
02:43:18,103 --> 02:43:22,241
THERE'S DISCUSSION OF EXTENDING

4650
02:43:22,241 --> 02:43:24,409
RFAs ACROSS A FEW DEADLINES,

4651
02:43:24,409 --> 02:43:26,378
JUST TO CONTINUE THE PRIORITY

4652
02:43:26,378 --> 02:43:29,414
AREA AND THE WORK THAT GOES ON,

4653
02:43:29,414 --> 02:43:31,216
SORT OF IDENTIFYING THAT AND

4654
02:43:31,216 --> 02:43:33,018
HOPING TO GET GOOD RESEARCH IN

4655
02:43:33,018 --> 02:43:35,387
THE AREA GOING.

4656
02:43:35,387 --> 02:43:38,290
>> RAJITA, ABSOLUTELY AND
WE DO

4657
02:43:38,290 --> 02:43:38,624
THAT.

4658
02:43:38,624 --> 02:43:41,693
THERE ARE TWO WAYS OF COURSE OF

4659
02:43:41,693 --> 02:43:43,595
GOING THROUGH IT, ONE WAS THE

4660
02:43:43,595 --> 02:43:44,830
NUMBER OF APPLICATIONS WE GOT IN

4661
02:43:44,830 --> 02:43:46,465
TERMS OF A REQUEST FOR

4662
02:43:46,465 --> 02:43:47,833
APPLICATION, SO IN A SPECIFIC

4663
02:43:47,833 --> 02:43:49,201
TOPIC AREA AND WHETHER IT COVERS

4664
02:43:49,201 --> 02:43:51,503
BASICALLY SUFFICIENTLY WELL THE

4665
02:43:51,503 --> 02:43:53,238
AREAS THAT ARE RELEVANT.

4666
02:43:53,238 --> 02:43:56,508
AND IF THERE WERE INDEED

4667
02:43:56,508 --> 02:43:58,911
INVESTIGATORS THAT HAVE

4668
02:43:58,911 --> 02:44:00,045
MERITORIOUS PROPOSALS BUT DIDN'T

4669
02:44:00,045 --> 02:44:02,714
REACH IT, WE PERHAPS CAN COME TO

4670
02:44:02,714 --> 02:44:04,049
THE REGULAR MECHANISM AND GUIDE

4671
02:44:04,049 --> 02:44:04,883
THEM THROUGH IT.

4672
02:44:04,883 --> 02:44:06,018
AND THERE'S BEEN ALSO INSTANCES

4673
02:44:06,018 --> 02:44:08,520
WHERE WE HAVE AN RFA AND WE

4674
02:44:08,520 --> 02:44:10,923
DON'T FEEL THAT WE WERE ABLE TO

4675
02:44:10,923 --> 02:44:13,759
CAPTURE ALL OF THE

4676
02:44:13,759 --> 02:44:14,960
POSSIBILITIES, SO WE REISSUE IT.

4677
02:44:14,960 --> 02:44:17,162
SO YES, WE TREAT THESE THINGS

4678
02:44:17,162 --> 02:44:18,497
WITH FLEXIBILITY, DEPENDING ON

4679
02:44:18,497 --> 02:44:19,298
THE OUTCOMES.

4680
02:44:19,298 --> 02:44:29,541
BY ALL MEANS.

4681
02:44:35,647 --> 02:44:36,582
RAJITA, DID THAT ANSWER YOUR

4682
02:44:36,582 --> 02:44:37,082
QUESTION?

4683
02:44:37,082 --> 02:44:39,484
>> YES, YES, IT ABSOLUTELY
DID.

4684
02:44:39,484 --> 02:44:41,453
YOU KNOW, I HAVE SEEN SOME

4685
02:44:41,453 --> 02:44:44,189
RFAs THAT ARE OPEN FOR A FEW

4686
02:44:44,189 --> 02:44:45,490
DEADLINES AND IT'S ENCOURAGING

4687
02:44:45,490 --> 02:44:50,963
TO SEE THAT THEY COULD GET SHEP

4688
02:44:50,963 --> 02:44:51,930
SHEPHERDED INTO THE REGULAR

4689
02:44:51,930 --> 02:44:52,130
POOL.

4690
02:44:52,130 --> 02:44:54,433
SOMETIMES I THINK THAT MAYBE

4691
02:44:54,433 --> 02:44:57,469
THERE ARE APPLICATIONS THAT DO

4692
02:44:57,469 --> 02:45:00,105
DROPOFF AND FALL TO THE WAYSIDE

4693
02:45:00,105 --> 02:45:01,273
WHEN THERE ARE GREAT IDEAS.

4694
02:45:01,273 --> 02:45:05,677
BUT AGAIN, IF YOU'RE TRACK BEING

4695
02:45:05,677 --> 02:45:07,746
THEM, THAT'S FANTASTIC.

4696
02:45:07,746 --> 02:45:09,081
>>  -- IS VERY RIGOROUS
WITH

4697
02:45:09,081 --> 02:45:12,017
THAT AND THEY WILL BRING UP

4698
02:45:12,017 --> 02:45:15,988
GRANTS THAT ARE VERY, VERY --

4699
02:45:15,988 --> 02:45:18,924
SOMEONE WITH A LOT OF POTENTIAL

4700
02:45:18,924 --> 02:45:20,626
THAT DIDN'T DO WELL ON THEIR

4701
02:45:20,626 --> 02:45:21,526
REVIEW, THEN THEY WORK WITH THEM

4702
02:45:21,526 --> 02:45:22,628
TO BE MORE SUCCESSFUL.

4703
02:45:22,628 --> 02:45:25,664
SO THEY ARE PROACTIVE IN THAT

4704
02:45:25,664 --> 02:45:26,198
PROCESS.

4705
02:45:26,198 --> 02:45:27,766
AND THE SAME THING, SOMETIMES --

4706
02:45:27,766 --> 02:45:29,468
FOR WHATEVER REASON, I GUESS

4707
02:45:29,468 --> 02:45:30,602
SOMETIMES -- IF YOU WANT TO

4708
02:45:30,602 --> 02:45:32,938
BUILD A NEW AREA OF SCIENCE, FOR

4709
02:45:32,938 --> 02:45:34,506
EXAMPLE, AND THIS HAPPENED WITH

4710
02:45:34,506 --> 02:45:35,607
THE SOCIAL DETERMINANTS OF

4711
02:45:35,607 --> 02:45:38,777
HEALTH FOR ONE OF OUR --

4712
02:45:38,777 --> 02:45:39,878
RELEASES, AND WE DIDN'T GET

4713
02:45:39,878 --> 02:45:43,916
SUFFICIENT APPLICATIONS, SO WE

4714
02:45:43,916 --> 02:45:48,287
HAVE BEEN REISSUING THE RFA

4715
02:45:48,287 --> 02:45:49,721
BECAUSE, AGAIN, IT'S MUCH HARDER

4716
02:45:49,721 --> 02:45:52,224
WHEN YOU'RE GETTING INTO A NEW

4717
02:45:52,224 --> 02:45:53,425
AREA SINCE PEOPLE HAVEN'T REALLY

4718
02:45:53,425 --> 02:45:54,860
THOUGHT ABOUT IT, SO BY KEEPING

4719
02:45:54,860 --> 02:45:57,362
IT THERE, YOU INCREASE THE

4720
02:45:57,362 --> 02:45:58,463
LIKELIHOOD OF PEOPLE GETTING

4721
02:45:58,463 --> 02:46:01,099
EXCITED ABOUT IT, AND GETTING

4722
02:46:01,099 --> 02:46:01,733
BETTER PROPOSALS.

4723
02:46:01,733 --> 02:46:04,169
SO YES, THIS IS SOMETHING THAT

4724
02:46:04,169 --> 02:46:08,307
WE NEED TO DO.

4725
02:46:08,307 --> 02:46:09,808
BECAUSE IT IS ACTUALLY THE WAY

4726
02:46:09,808 --> 02:46:13,111
THAT WE MAXIMIZE OUR ABILITY TO

4727
02:46:13,111 --> 02:46:15,514
ADVANCE SCIENCE AREAS THAT ARE

4728
02:46:15,514 --> 02:46:16,415
VERY IMPORTANT FOR THE MISSION

4729
02:46:16,415 --> 02:46:18,717
OF THE INSTITUTE.

4730
02:46:18,717 --> 02:46:25,490
>> THANK YOU SO MUCH.

4731
02:46:25,490 --> 02:46:27,159
>> SUSAN, I DON'T SEE ANY
MORE

4732
02:46:27,159 --> 02:46:27,759
HANDS RAISED.

4733
02:46:27,759 --> 02:46:29,161
>> I DO NOT EITHER.

4734
02:46:29,161 --> 02:46:30,562
SO WE CAN THEN GO ON TO THE

4735
02:46:30,562 --> 02:46:32,464
CONCEPT CLEARANCE.

4736
02:46:32,464 --> 02:46:32,898
 PART OF THE

4737
02:46:32,898 --> 02:46:34,833
MEETING.

4738
02:46:34,833 --> 02:46:35,801
>> OKAY.

4739
02:46:35,801 --> 02:46:37,903
SO IF WE GO TO THE CONCEPT

4740
02:46:37,903 --> 02:46:41,306
CLEARANCE, I GUESS -- DO YOU

4741
02:46:41,306 --> 02:46:43,575
WANT ME TO DRIVE OR DO YOU WANT

4742
02:46:43,575 --> 02:46:45,210
TO DRIVE, SUSAN?

4743
02:46:45,210 --> 02:46:45,911
WHAT'S YOUR FAVORITE?

4744
02:46:45,911 --> 02:46:47,312
>> I'M HAPPY TO DRIVE.

4745
02:46:47,312 --> 02:46:49,481
>> DRIVE!

4746
02:46:49,481 --> 02:46:53,885
JUST DON'T GO TOO FAST.

4747
02:46:53,885 --> 02:46:55,620
>> SO WE HAVE A NUMBER OF

4748
02:46:55,620 --> 02:46:57,489
CONCEPTS BEING PRESENTED.

4749
02:46:57,489 --> 02:47:00,025
WE USUALLY DO QUITE BRIEF

4750
02:47:00,025 --> 02:47:01,326
PRESENTATIONS, BUT YOU HAVE

4751
02:47:01,326 --> 02:47:02,494
INFORMATION IN THE ELECTRONIC

4752
02:47:02,494 --> 02:47:04,730
COUNCIL BOOK ABOUT THEM.

4753
02:47:04,730 --> 02:47:05,931
BUT PLEASE STOP US WHEN WE'RE

4754
02:47:05,931 --> 02:47:07,432
DOING THE PRESENTATION IF YOU

4755
02:47:07,432 --> 02:47:08,533
WANT TO HAVE MORE OF A

4756
02:47:08,533 --> 02:47:10,602
DISCUSSION OR IF YOU HAVE ANY

4757
02:47:10,602 --> 02:47:13,438
QUESTIONS ABOUT THESE CONCEPTS.

4758
02:47:13,438 --> 02:47:14,840
SO THE FIRST GROUP IS GOING TO

4759
02:47:14,840 --> 02:47:16,708
COME FROM THE DIVISION OF

4760
02:47:16,708 --> 02:47:18,477
NEUROSCIENCE AND BEHAVIOR, AND

4761
02:47:18,477 --> 02:47:20,746
KATHLEEN BORGMANN IS GOING TO BE

4762
02:47:20,746 --> 02:47:21,780
THE PERSON PRESENTING THEM.

4763
02:47:21,780 --> 02:47:24,383
>> GOOD AFTERNOON.

4764
02:47:24,383 --> 02:47:26,651
THE FIRST CONCEPT IS ADVANCING

4765
02:47:26,651 --> 02:47:27,753
RESEARCH ON PLEAK ALREADY

4766
02:47:27,753 --> 02:47:29,388
TARGETS AND MECHANISMS THAT

4767
02:47:29,388 --> 02:47:30,922
INFLUENCE THE INTERPLAY BETWEEN

4768
02:47:30,922 --> 02:47:35,260
SEX HORMONES, ADDICTIVE SUCK

4769
02:47:35,260 --> 02:47:36,261
SUBSTANCES AND HIV █INFECTION.

4770
02:47:36,261 --> 02:47:41,733
IT WAS PROPOSED BY DR. SAM

4771
02:47:41,733 --> 02:47:42,367
ANANTHN.

4772
02:47:42,367 --> 02:47:44,202
DESPITE THE KNOWN NEXUS, OUR

4773
02:47:44,202 --> 02:47:45,537
KNOWLEDGE REGARDING THE

4774
02:47:45,537 --> 02:47:46,938
BIOCHEMICAL MECHANISMS BY WHICH

4775
02:47:46,938 --> 02:47:49,574
SEX HORMONES POSITIVELY OR

4776
02:47:49,574 --> 02:47:51,209
NECKTIVELY INFLUENCE THE COURSE

4777
02:47:51,209 --> 02:47:54,112
OF HIV INFECTION IN DRUG-USING

4778
02:47:54,112 --> 02:47:55,347
POPULATIONS IS LIMITED.

4779
02:47:55,347 --> 02:47:57,549
THIS CONCEPT WILL SUPPORT BASIC

4780
02:47:57,549 --> 02:47:59,384
RESEARCH ON DELINEATING THE

4781
02:47:59,384 --> 02:48:00,819
MECHANISMS BY WHICH HORMONES

4782
02:48:00,819 --> 02:48:02,988
INFLUENCE THE OUTCOME OF

4783
02:48:02,988 --> 02:48:06,391
CO-MORBID HIV AND DRUG USE AND

4784
02:48:06,391 --> 02:48:07,592
RESEARCH ON THE TRANSLATIONAL

4785
02:48:07,592 --> 02:48:08,660
POTENTIAL OF TARGETING SPECIFIC

4786
02:48:08,660 --> 02:48:11,263
MECHANISMS FOR THE DEVELOPMENT

4787
02:48:11,263 --> 02:48:12,464
OF EFFECTIVE INDIVIDUALIZED

4788
02:48:12,464 --> 02:48:14,699
THERAPEUTIC APPROACHES TO TREAT

4789
02:48:14,699 --> 02:48:17,436
HIV IN PEOPLE WITH SUBSTANCE USE

4790
02:48:17,436 --> 02:48:20,172
DISORDERS.

4791
02:48:20,172 --> 02:48:23,108
OUR SECOND CONCEPT IS TITLED

4792
02:48:23,108 --> 02:48:23,875
MITOCHONDRIAL-ASSOCIATED

4793
02:48:23,875 --> 02:48:26,812
MECHANISMS OF NEUROPATHOLOGICAL

4794
02:48:26,812 --> 02:48:28,580
AND IMMUNODEFICIENT AGING IN THE

4795
02:48:28,580 --> 02:48:32,751
CONTEXT OF HIV AND SUD.

4796
02:48:32,751 --> 02:48:33,819
I PROPOSE THIS HAD CONCEPT.

4797
02:48:33,819 --> 02:48:37,689
THE LIFELONG CONSEQUE CONSEQUENF

4798
02:48:37,689 --> 02:48:39,825
LIVING WITH HIV HERITAGE

4799
02:48:39,825 --> 02:48:41,293
ANTIRETROVIRAL THERAPIES AND/OR

4800
02:48:41,293 --> 02:48:43,195
USE OF ADDICTIVE SUBSTANCES

4801
02:48:43,195 --> 02:48:44,529
REMAINS UNDERSTUDIED.

4802
02:48:44,529 --> 02:48:46,731
THESE LIFE FACTORS HAVE BEEN

4803
02:48:46,731 --> 02:48:48,233
INDEPENDENTLY ASSOCIATED WITH

4804
02:48:48,233 --> 02:48:51,169
MECHANISMS THAT CONTRIBUTE TO

4805
02:48:51,169 --> 02:48:54,339
NEUROPATPATHOLOGICAL AND -- AGIG

4806
02:48:54,339 --> 02:48:56,408
SUCH AS INFLAMMATION, OXIDATIVE

4807
02:48:56,408 --> 02:48:59,411
STRESS AND CELLULAR SENESCENCE,

4808
02:48:59,411 --> 02:49:01,546
ALSO REGULATED BY MYOCON DREE A

4809
02:49:01,546 --> 02:49:02,747
IN BRAIN AND IMMUNE CELLS.

4810
02:49:02,747 --> 02:49:04,149
THIS CONCEPT WILL SUPPORT BASIC

4811
02:49:04,149 --> 02:49:06,251
RESEARCH VIGHTING MITOCHONDRIAL

4812
02:49:06,251 --> 02:49:08,854
ASSOCIATED MECHANISMS OF

4813
02:49:08,854 --> 02:49:10,622
PROTECTIVE AND PATHOGENIC AGING

4814
02:49:10,622 --> 02:49:13,125
IN PEOPLE LIVING WITH HIV AND

4815
02:49:13,125 --> 02:49:16,728
SUBSTANCE USE DISORDERS.

4816
02:49:16,728 --> 02:49:18,463
OUR THIRD CONCEPT IS WASTE NOT,

4817
02:49:18,463 --> 02:49:20,966
WANT NOT:  EXPLORING

4818
02:49:20,966 --> 02:49:22,200
INTERACTIONS BETWEEN BRAIN WASTE

4819
02:49:22,200 --> 02:49:24,569
CLEARANCE AND RENEWAL SYSTEMS IN

4820
02:49:24,569 --> 02:49:27,405
HIV AND ADDICTION.

4821
02:49:27,405 --> 02:49:30,809
I ALSO PROPOSED THIS CONCEPT.

4822
02:49:30,809 --> 02:49:33,111
WHILE THE WASTE CLEARANCE AND

4823
02:49:33,111 --> 02:49:35,981
RENEWAL SYSTEMS IS HIGHLY

4824
02:49:35,981 --> 02:49:37,949
DEPENDENT ON SLEEP, IT IS ALSO

4825
02:49:37,949 --> 02:49:39,684
REGULATED BY OTHER PHYSIOLOGICAL

4826
02:49:39,684 --> 02:49:40,886
MECHANISMS THAT ARE, IN TURN,

4827
02:49:40,886 --> 02:49:43,855
LIKELY AFFECTED BY SUBSTANCE USE

4828
02:49:43,855 --> 02:49:44,723
AND HIV.

4829
02:49:44,723 --> 02:49:46,558
DESPITE EXTENSIVE RESEARCH IN

4830
02:49:46,558 --> 02:49:48,093
ALZHEIMER'S DISEASE AND AGING,

4831
02:49:48,093 --> 02:49:49,961
THE MECHANISMS REGULATING THE

4832
02:49:49,961 --> 02:49:51,363
WASTE CLEARANCE AND RENEWAL

4833
02:49:51,363 --> 02:49:52,564
SYSTEM IN THE CONTEXT OF

4834
02:49:52,564 --> 02:49:55,066
SUBSTANCE USE DISORDERS AND HIV

4835
02:49:55,066 --> 02:49:57,169
ARE LARGELY UNKNOWN.

4836
02:49:57,169 --> 02:49:59,304
THIS CONCEPT WILL SUPPORT BASIC

4837
02:49:59,304 --> 02:50:01,406
RESEARCH INTO ITS ROLE IN

4838
02:50:01,406 --> 02:50:04,142
REGULATING ADDICTION AND HIV

4839
02:50:04,142 --> 02:50:05,443
BRAIN INFECTION AND IMMUNE

4840
02:50:05,443 --> 02:50:06,878
INJURY, WHICH WILL PROVIDE NEW

4841
02:50:06,878 --> 02:50:08,813
INSIGHTS FOR THE DEVELOPMENT OF

4842
02:50:08,813 --> 02:50:11,783
EFFECTIVE INTERVENTIONS.

4843
02:50:11,783 --> 02:50:14,519
AND OUR FINAL CONCEPT FOR THE

4844
02:50:14,519 --> 02:50:15,086
DIVISION OF NEUROSCIENCE AND

4845
02:50:15,086 --> 02:50:18,523
BEHAVIOR IS MECHANISMS OF

4846
02:50:18,523 --> 02:50:20,025
CELL-TO-CELL INTERACTIONS AND

4847
02:50:20,025 --> 02:50:21,526
COMMUNICATION IN CENTRAL NERVOUS

4848
02:50:21,526 --> 02:50:23,695
SYSTEM HIV REPLICATION, AND THIS

4849
02:50:23,695 --> 02:50:29,167
WAS PROPOSED BY DR. ANNE TSAI.

4850
02:50:29,167 --> 02:50:32,671
HIV COMPARTMENTALIZES WITHIN

4851
02:50:32,671 --> 02:50:33,872
BRAIN IMMUNE CELLS TO ESTABLISH

4852
02:50:33,872 --> 02:50:34,739
RESERVOIRS.

4853
02:50:34,739 --> 02:50:36,274
RECENT STUDIES HAVE SHOWN THAT

4854
02:50:36,274 --> 02:50:37,275
ASTROGLIA BECOME INFECTED

4855
02:50:37,275 --> 02:50:39,010
THROUGH A CELL-TO-CELL CONTACT

4856
02:50:39,010 --> 02:50:39,778
MECHANISM.

4857
02:50:39,778 --> 02:50:42,847
UNDERSTANDING THE MECHANISMS OF

4858
02:50:42,847 --> 02:50:44,482
CELL COMMUNICATION AND VIRAL

4859
02:50:44,482 --> 02:50:45,684
TRANSFER UNDER THE INFLUENCE OF

4860
02:50:45,684 --> 02:50:47,018
SUBSTANCE USE IS ESSENTIAL FOR

4861
02:50:47,018 --> 02:50:48,753
AN HIV CURE.

4862
02:50:48,753 --> 02:50:50,956
THIS CONCEPT WILL SUPPORT

4863
02:50:50,956 --> 02:50:52,257
INVESTIGATIONS ON HOW SUBSTANCE

4864
02:50:52,257 --> 02:50:54,759
USE AFFECTS CELLULAR SIGNATURES

4865
02:50:54,759 --> 02:50:56,962
BY WHICH HIV LATENCY IS

4866
02:50:56,962 --> 02:50:58,396
INITIATED, ESTABLISHED AND

4867
02:50:58,396 --> 02:50:59,364
MAINTAINED IN THE CENTRAL

4868
02:50:59,364 --> 02:51:02,901
NERVOUS CYST TE. THANK YOU.

4869
02:51:02,901 --> 02:51:04,736
>> ARE THERE ANY QUESTIONS
OR

4870
02:51:04,736 --> 02:51:11,643
COMMENTS?

4871
02:51:11,643 --> 02:51:13,812
>> I JUST WANTED TO
COMMENT ON

4872
02:51:13,812 --> 02:51:16,214
THAT THEY'RE REALLY INCREDIBLY

4873
02:51:16,214 --> 02:51:17,749
TARGETING VERY CRITICAL ISSUES

4874
02:51:17,749 --> 02:51:18,950
THAT WE CURRENTLY ARE DEALING

4875
02:51:18,950 --> 02:51:25,390
WITH IN HIV PATHOGENESIS, BUT

4876
02:51:25,390 --> 02:51:26,591
SPECIFICALLY CORE CURE RESEARCH,

4877
02:51:26,591 --> 02:51:27,993
AND I THINK REALLY APPLAUDING

4878
02:51:27,993 --> 02:51:31,096
FOR THESE INITIATIVES.

4879
02:51:31,096 --> 02:51:36,101
>> THANK YOU.

4880
02:51:36,101 --> 02:51:40,572
ANYONE ELSE?

4881
02:51:40,572 --> 02:51:43,341
THEN WE CAN GO ON TO THE NEXT

4882
02:51:43,341 --> 02:51:44,976
CONCEPT, WHICH IS GOING TO BE

4883
02:51:44,976 --> 02:51:46,811
ON -- IT'S FROM THE OFFICE OF

4884
02:51:46,811 --> 02:51:48,780
RESEARCH TRAINING, DIVERSITY AND

4885
02:51:48,780 --> 02:51:50,048
DISPARITIES, AND IT'S PRESENTED

4886
02:51:50,048 --> 02:51:54,819
BY DR. YOHANSA FERNANDEZ.

4887
02:51:54,819 --> 02:51:56,254
I'M SORRY IF I MISPRONOUNCED

4888
02:51:56,254 --> 02:51:56,921
YOUR NAME.

4889
02:51:56,921 --> 02:51:57,289
>> YOU DID NOT.

4890
02:51:57,289 --> 02:51:58,156
THANK YOU SO MUCH.

4891
02:51:58,156 --> 02:51:59,691
APPRECIATE THAT.

4892
02:51:59,691 --> 02:52:02,294
WE ARE PRESENTING THE DATA

4893
02:52:02,294 --> 02:52:04,496
SCIENCE TRACK AWARD FOR RESEARCH

4894
02:52:04,496 --> 02:52:05,830
TRANSITION OR D-START.

4895
02:52:05,830 --> 02:52:07,799
DATA SCIENCE IS AN IMPORTANT

4896
02:52:07,799 --> 02:52:09,100
CROSS-CUTTING PRIORITY FOR NIDA,

4897
02:52:09,100 --> 02:52:10,869
AND INCREASING THE CAPACITY OF

4898
02:52:10,869 --> 02:52:12,170
EXPERTS IN ADDICTION RELATED

4899
02:52:12,170 --> 02:52:13,805
DATA SCIENCE IS CRITICAL.

4900
02:52:13,805 --> 02:52:15,106
THE CONCEPT IS INTENDED TO

4901
02:52:15,106 --> 02:52:16,641
FACILITATE THE ENTRY OF

4902
02:52:16,641 --> 02:52:18,376
INVESTIGATORS TO THE AREA OF

4903
02:52:18,376 --> 02:52:19,711
ADDICTION RELATED DATA SCIENCE

4904
02:52:19,711 --> 02:52:22,113
INCLUDING NEWLY INDEPENDENT DATA

4905
02:52:22,113 --> 02:52:23,214
SCIENTISTS OR ESTABLISHED

4906
02:52:23,214 --> 02:52:24,616
INVESTIGATORS SEEKING TO

4907
02:52:24,616 --> 02:52:27,319
INCORPORATE NOVEL AND CROSS --

4908
02:52:27,319 --> 02:52:29,521
CUTTING EDGE DATA SCIENCE

4909
02:52:29,521 --> 02:52:30,088
METHODOLOGIES INTO THEIR

4910
02:52:30,088 --> 02:52:32,357
RESEARCH PROGRAMS FOR THE FIRST

4911
02:52:32,357 --> 02:52:32,924
TIME.

4912
02:52:32,924 --> 02:52:34,459
APPLICANTS ARE ENCOURAGED TO USE

4913
02:52:34,459 --> 02:52:36,628
EXISTING DATASETS, FOLLOW FAIR

4914
02:52:36,628 --> 02:52:38,596
PRINCIPLES AND WHEN APPLICABLE,

4915
02:52:38,596 --> 02:52:39,798
ATTEND TO ETHICAL CONCERNS IN

4916
02:52:39,798 --> 02:52:41,900
THE CONDUCT OF RESEARCH

4917
02:52:41,900 --> 02:52:43,501
INVOLVING HUMAN SUBJECTS.

4918
02:52:43,501 --> 02:52:45,036
ULTIMATELY, THE AIM IS TO

4919
02:52:45,036 --> 02:52:46,037
EXPEDITE THE DEVELOPMENT OF

4920
02:52:46,037 --> 02:52:48,206
ROBUST RESEARCH PROGRAMS FOCUSED

4921
02:52:48,206 --> 02:52:50,075
ON THE CONVERGENCE OF INNOVATIVE

4922
02:52:50,075 --> 02:52:51,743
DATA SCIENCE TECHNIQUES AND

4923
02:52:51,743 --> 02:52:54,679
ADDICTION RESEARCH WITH INITIAL

4924
02:52:54,679 --> 02:52:59,284
PROPOSALS SERVING AS PRECURSORS

4925
02:52:59,284 --> 02:53:01,353
FOR MORE SUBSTANTIVE RESEARCH

4926
02:53:01,353 --> 02:53:01,653
PORTFOLIOS.

4927
02:53:01,653 --> 02:53:01,986
THANK YOU.

4928
02:53:01,986 --> 02:53:03,888
>> THANK YOU.

4929
02:53:03,888 --> 02:53:13,832
ANY COMMENTS, QUESTIONS?

4930
02:53:13,832 --> 02:53:14,065
OKAY.

4931
02:53:14,065 --> 02:53:16,034
THANK YOU VERY MUCH.

4932
02:53:16,034 --> 02:53:19,571
THE LAST CONCEPT IS FROM THE

4933
02:53:19,571 --> 02:53:21,940
DIVISION OF EPIDEMIOLOGY,

4934
02:53:21,940 --> 02:53:23,341
SERVICES AND PREVENTION, AND

4935
02:53:23,341 --> 02:53:25,310
ANGELA LEE-WINN WILL BE

4936
02:53:25,310 --> 02:53:26,611
PRESENTING.

4937
02:53:26,611 --> 02:53:28,513
>> THANK YOU, AND GOOD

4938
02:53:28,513 --> 02:53:28,913
AFTERNOON.

4939
02:53:28,913 --> 02:53:30,782
WE'RE PROPOSING A CONCEPT TITLED

4940
02:53:30,782 --> 02:53:32,550
RESEARCH TO ADDRESS SYSTEMIC AND

4941
02:53:32,550 --> 02:53:33,885
STRUCTURAL BARRIERS AND

4942
02:53:33,885 --> 02:53:36,488
FACILITATORS TO IMPROVE THE HIV

4943
02:53:36,488 --> 02:53:38,390
PRE-EXPOSURE PROPHYLAXIS CARE

4944
02:53:38,390 --> 02:53:39,657
CONTINUUM FOR PEOPLE WHO USE

4945
02:53:39,657 --> 02:53:43,261
SUBSTANCES.

4946
02:53:43,261 --> 02:53:44,329
PRE-EXPOSURE PROPHYLAXIS, ALSO

4947
02:53:44,329 --> 02:53:46,765
KNOWN AS PREP, IS A SAFE, HIGHLY

4948
02:53:46,765 --> 02:53:48,833
EFFECTIVE MEDICATION FOR

4949
02:53:48,833 --> 02:53:50,502
PREVENTING TRANSMISSION OF HIV

4950
02:53:50,502 --> 02:53:52,704
FROM SEX OR INJECTION DRUG USE,

4951
02:53:52,704 --> 02:53:54,038
YET CONTINUES TO BE

4952
02:53:54,038 --> 02:53:56,541
UNDERUTILIZED, PARTICULARLY

4953
02:53:56,541 --> 02:53:57,976
AMONG PEOPLE WHO USE SUBSTANCES.

4954
02:53:57,976 --> 02:54:00,145
THE GOAL OF THIS CONCEPT IS TO

4955
02:54:00,145 --> 02:54:02,013
SUPPORT RESEARCH TO EXAMINE AND

4956
02:54:02,013 --> 02:54:03,481
ADDRESS SYSTEMIC AND STRUCTURAL

4957
02:54:03,481 --> 02:54:04,816
FACTORS THAT IMPEDE OR

4958
02:54:04,816 --> 02:54:07,018
FACILITATE THE PREP AWARENESS,

4959
02:54:07,018 --> 02:54:08,887
UPTAKE, AND ADHERENCE AMONG

4960
02:54:08,887 --> 02:54:11,189
PEOPLE WHO USE SUBSTANCES.

4961
02:54:11,189 --> 02:54:12,924
PROJECTS WILL DEVELOP, IMPLEMENT

4962
02:54:12,924 --> 02:54:14,793
AND EVALUATE EFFECTIVE

4963
02:54:14,793 --> 02:54:15,460
STRATEGIES THAT MEET THE NEEDS

4964
02:54:15,460 --> 02:54:18,396
OF PEOPLE WHO USE SUBSTANCES TO

4965
02:54:18,396 --> 02:54:19,597
IMPROVE THE PREP CARE CONTINUUM.

4966
02:54:19,597 --> 02:54:24,302
THANK YOU.

4967
02:54:24,302 --> 02:54:25,203
>> THANK YOU.

4968
02:54:25,203 --> 02:54:34,479
AGAIN, ANY COMMENTS, QUESTIONS?

4969
02:54:34,479 --> 02:54:35,346
OKAY.

4970
02:54:35,346 --> 02:54:37,982
THEN THANK YOU VERY MUCH.

4971
02:54:37,982 --> 02:54:39,651
NORA, I CAN TURN IT BACK OVER TO

4972
02:54:39,651 --> 02:54:39,851
YOU.

4973
02:54:39,851 --> 02:54:41,486
WE DID NOT RECEIVE ANY PUBLIC

4974
02:54:41,486 --> 02:54:44,355
COMMENTS AHEAD OF TIME.

4975
02:54:44,355 --> 02:54:47,058
>> SO IF WE DON'T HAVE
RECEIVED

4976
02:54:47,058 --> 02:54:49,127
ANY PUBLIC COMMENT BEFORE OUR

4977
02:54:49,127 --> 02:54:50,995
TIME, WE ARE UNABLE TO ACTUALLY

4978
02:54:50,995 --> 02:54:53,498
ANSWER THEM BECAUSE THERE ARE

4979
02:54:53,498 --> 02:54:55,500
NONE, BUT IF YOU DO WANT, IF YOU

4980
02:54:55,500 --> 02:54:57,135
HAVE QUESTIONS, COMMENTS THAT

4981
02:54:57,135 --> 02:54:59,304
YOU WOULD LIKE US TO BRING UP IN

4982
02:54:59,304 --> 02:55:02,507
THE NEXT COUNCIL, WHICH WILL BE

4983
02:55:02,507 --> 02:55:03,775
MAY, PLEASE SEND THEM TO

4984
02:55:03,775 --> 02:55:06,277
DR. SUSAN WEISS.

4985
02:55:06,277 --> 02:55:08,379
AND HAVING GONE THROUGH THE

4986
02:55:08,379 --> 02:55:10,014
PROGRAM AND THERE'S NOTHING MORE

4987
02:55:10,014 --> 02:55:11,349
ON THE AGENDA, I'M GOING TO GIVE

4988
02:55:11,349 --> 02:55:13,318
EVERYONE A CHANCE IF THEY WANT

4989
02:55:13,318 --> 02:55:14,986
ANYTHING THAT THEY WOULD WANT TO

4990
02:55:14,986 --> 02:55:16,621
BRING UP BEFORE WE ADJOURN.

4991
02:55:16,621 --> 02:55:18,389
SO PLEASE RAISE YOUR HAND, AND

4992
02:55:18,389 --> 02:55:23,962
IF I DON'T SEE ANY RAISED HAN

4993
02:55:23,962 --> 02:55:29,634
HANDS -- IT'S 5, 4, 3, 2, 1.

4994
02:55:29,634 --> 02:55:31,069
I DON'T SEE ANY HANDS.

4995
02:55:31,069 --> 02:55:35,540
SO I THINK THAT WITH THAT, WE

4996
02:55:35,540 --> 02:55:36,808
CAN ADJOURN, AND I WANT TO THANK

4997
02:55:36,808 --> 02:55:39,811
ALL OF THE COUNCILMEMBERS VERY

4998
02:55:39,811 --> 02:55:40,245
MUCH.

4999
02:55:40,245 --> 02:55:41,880
THEIR WILLINGNESS TO HELP US.

5000
02:55:41,880 --> 02:55:44,282
AND EVEN THOUGH WE ARE RIGHT NOW

5001
02:55:44,282 --> 02:55:47,585
ENDING OUR COUNCIL, THAT DOES

5002
02:55:47,585 --> 02:55:49,420
NOT MEAN THAT WE ARE

5003
02:55:49,420 --> 02:55:50,421
DISCONNECTING OUR COMMUNICATION

5004
02:55:50,421 --> 02:55:51,623
AND IF YOU HAVE SUGGESTIONS,

5005
02:55:51,623 --> 02:55:57,195
PLEASE REACH OUT TO ME, SUSAN

5006
02:55:57,195 --> 02:55:59,063
WILSON, AND WE WILL ADDRESS YOUR

5007
02:55:59,063 --> 02:56:00,164
CONCERN, SO IF YOU HAVE

5008
02:56:00,164 --> 02:56:03,535
QUESTIONS OR SUGGESTIONS.

5009
02:56:03,535 --> 02:56:05,837
MEANWHILE, I HOPE YOU ENJOY THE

5010
02:56:05,837 --> 02:56:06,905
REST OF THE DAY, AND THANKS VERY

5011
02:56:06,905 --> 02:56:08,706
MUCH FOR YOUR ATTENTION.

5012
02:56:08,706 --> 02:56:10,441
>> AND I JUST WANT TO
THANK YOU

5013
02:56:10,441 --> 02:56:10,675
AS WELL.

5014
02:56:10,675 --> 02:56:13,044
WE REALLY APPRECIATE YOUR TIME

5015
02:56:13,044 --> 02:56:13,912
AND YOUR ATTENTION.

5016
02:56:13,912 --> 02:56:15,480
>> LOOK FORWARD TO SEEING
YOU IN

5017
02:56:15,480 --> 02:56:16,347
PERSON IN MAY.

5018
02:56:16,347 --> 02:56:18,349
>> YES, DEFINITELY.

5019
02:56:18,349 --> 02:56:19,384
>> THANK YOU.

5020
02:56:19,384 --> 02:56:29,761
>> THANK YOU, BYE-BYE.