1
00:00:05,240 --> 00:00:09,560
I'M HAPPY TO CALL INTO ORDER THE

2
00:00:09,560 --> 00:00:11,000
OPEN SESSION OF OUR 79th

3
00:00:11,000 --> 00:00:14,840
MEETING OF THE NATIONAL ADVISORY

4
00:00:14,840 --> 00:00:16,040
COUNCIL FOR COMPLEMENTARY AND

5
00:00:16,040 --> 00:00:16,480
INTEGRATIVE HEALTH.

6
00:00:16,480 --> 00:00:18,000
I WANT TO NOTE FOR THE RECORD

7
00:00:18,000 --> 00:00:22,720
THIS MEETING IS BEING HELD 

8
00:00:22,720 --> 00:00:23,800
VIRTUALLY FOR ALL PARTICIPANTS,

9
00:00:23,800 --> 00:00:25,360
INCLUDING NIH STAFF, COUNCIL

10
00:00:25,360 --> 00:00:26,320
MEMBERS, AND THE PUBLIC.

11
00:00:26,320 --> 00:00:28,280
THENLS R. HENCE THERE IS NO

12
00:00:28,280 --> 00:00:34,080
IN-PERSON ATTENDANCE FOR THIS

13
00:00:34,080 --> 00:00:34,320
MEETING.

14
00:00:34,320 --> 00:00:37,880
I'M PARTAP KHALSA, EXECUTIVE 

15
00:00:37,880 --> 00:00:40,160
SECRETARY FOR THIS COUNCIL, I'M

16
00:00:40,160 --> 00:00:41,600
DESIGNATED FEDERAL OFFICIAL FOR

17
00:00:41,600 --> 00:00:45,240
THIS MEETING OF THE COUNCIL.

18
00:00:45,240 --> 00:00:48,720
THIS MEETING IS BEING VIDEOCAST

19
00:00:48,720 --> 00:00:52,880
LIVE BY THE NIH VIDEOCAST

20
00:00:52,880 --> 00:00:55,360
SERVICE TO ANYONE WHO WISHES TO

21
00:00:55,360 --> 00:00:57,920
ATTEND OUR -- TO LISTEN TO THIS

22
00:00:57,920 --> 00:00:59,760
MEETING AND SEE IT.

23
00:00:59,760 --> 00:01:02,520
SO, EVERYONE WHO IS -- ALL

24
00:01:02,520 --> 00:01:04,160
COUNCIL MEMBERS WERE ON BY ZOOM

25
00:01:04,160 --> 00:01:05,400
CALL, EVERYONE ELSE IN THE WORLD

26
00:01:05,400 --> 00:01:09,640
CAN SEE YOUR ZOOM FEED RIGHT

27
00:01:09,640 --> 00:01:09,800
NOW.

28
00:01:09,800 --> 00:01:12,840
SO KEEP A SMILE ON YOUR FACE

29
00:01:12,840 --> 00:01:13,320
PLEASE.

30
00:01:13,320 --> 00:01:17,360
THIS IS REQUIRED BY TITLE 42 OF

31
00:01:17,360 --> 00:01:21,680
THE U.S. CODE OF LAWS GOVERNING

32
00:01:21,680 --> 00:01:23,600
NIH AND NCCIH, SECTION 287 OF

33
00:01:23,600 --> 00:01:25,280
TITLE 42, CONVENED IN ACCORDANCE

34
00:01:25,280 --> 00:01:30,000
WITH THE FEDERAL ADVISORY 

35
00:01:30,000 --> 00:01:31,720
COMMITTEE ACT, PUBLIC LAW 92.463

36
00:01:31,720 --> 00:01:33,280
CODIFIED IN TITLE 5 OF THE U.S.

37
00:01:33,280 --> 00:01:35,520
CODE OF LAWS.

38
00:01:35,520 --> 00:01:37,520
I NOTE THE CLOSED SESSION WAS

39
00:01:37,520 --> 00:01:39,280
HELD EARLIER THIS MORNING,

40
00:01:39,280 --> 00:01:41,120
CLOSED TO THE PUBLIC, IN

41
00:01:41,120 --> 00:01:41,720
ACCORDANCE WITH THE GOVERNMENT

42
00:01:41,720 --> 00:01:50,320
IN THE SUNSHINE ACT ACT, PUBLIC 

43
00:01:50,320 --> 00:01:54,000
LAW 94-409, CODIFIED IN TITLE 5

44
00:01:54,000 --> 00:01:54,920
FOR FEDERAL AGENCIES, SECTION

45
00:01:54,920 --> 00:01:55,320
552.

46
00:01:55,320 --> 00:01:57,640
WE WILL ENDEAVOR TO FINISH THIS

47
00:01:57,640 --> 00:02:00,800
AFTERNOON BY AROUND 4:30 P.M.

48
00:02:00,800 --> 00:02:01,920
EASTERN TIME.

49
00:02:01,920 --> 00:02:03,320
THE OPEN SESSION OF COUNCIL IS

50
00:02:03,320 --> 00:02:05,720
OPEN TO THE GENERAL PUBLIC TO

51
00:02:05,720 --> 00:02:09,200
ATTEND VIA THE -- AS PREVIOUSLY

52
00:02:09,200 --> 00:02:10,080
MENTIONED, LIVE NIH VIDEOCAST,

53
00:02:10,080 --> 00:02:12,840
AND THUS CAN AND MAY BE VIEWED

54
00:02:12,840 --> 00:02:15,360
BY INDIVIDUALS ACROSS THE

55
00:02:15,360 --> 00:02:16,320
COUNTRY AND THE WORLD.

56
00:02:16,320 --> 00:02:18,920
I WANT TO NOTE FOR THE PUBLIC

57
00:02:18,920 --> 00:02:19,920
WE'VE ALREADY DONE INTRODUCTIONS

58
00:02:19,920 --> 00:02:25,360
OF ALL THE COUNCIL MEMBERS TO

59
00:02:25,360 --> 00:02:26,800
THEMSELVES, AND THEIR ATTENDANCE

60
00:02:26,800 --> 00:02:28,560
IS ALSO AVAILABLE BY FEDERAL

61
00:02:28,560 --> 00:02:29,720
REGISTRY NOTICE.

62
00:02:29,720 --> 00:02:31,720
THIS OPEN SESSION WILL INCLUDE

63
00:02:31,720 --> 00:02:34,000
THE REMARKS BY MYSELF NOW AND A

64
00:02:34,000 --> 00:02:38,800
REVIEW OF AND VOTE FOR THE

65
00:02:38,800 --> 00:02:39,920
REQUIRED ANNUAL COUNCIL

66
00:02:39,920 --> 00:02:41,320
OPERATING PROCEDURES.

67
00:02:41,320 --> 00:02:43,320
ONCE WE CONCLUDE THAT

68
00:02:43,320 --> 00:02:45,560
ADMINISTRATIVE DETAIL, WE'LL

69
00:02:45,560 --> 00:02:50,400
HAVE A -- IT WILL BE FOLLOWED BY

70
00:02:50,400 --> 00:02:52,120
NCCIH DIRECTOR'S REPORT TO

71
00:02:52,120 --> 00:02:53,480
COUNCIL, PRESENTATION BY DR.

72
00:02:53,480 --> 00:02:54,760
EDWARDS ON FUND OPPORTUNITY

73
00:02:54,760 --> 00:02:56,720
ANNOUNCEMENTS FOR PAIN RESEARCH

74
00:02:56,720 --> 00:02:58,360
THAT NCCIH IS LEADING OR

75
00:02:58,360 --> 00:02:59,480
PARTICIPATING IN.

76
00:02:59,480 --> 00:03:03,160
FOLLOWING THAT, WE WILL BREAK

77
00:03:03,160 --> 00:03:05,520
FOR LUNCH, AND FOLLOWING LUNCH

78
00:03:05,520 --> 00:03:07,000
WILL RECONVENE WITH A

79
00:03:07,000 --> 00:03:09,200
PRESENTATION BY DR. CRISWELL ON

80
00:03:09,200 --> 00:03:10,840
THE MISSION OF THE NATIONAL

81
00:03:10,840 --> 00:03:12,600
INSTITUTE OF ARTHRITIS AND

82
00:03:12,600 --> 00:03:13,800
MUSCULOSKELETAL AND SKIN

83
00:03:13,800 --> 00:03:18,080
DISEASES, AND ITS PAIN RESEARCH

84
00:03:18,080 --> 00:03:20,040
PORTFOLIO AND SHARED INTERESTS

85
00:03:20,040 --> 00:03:20,800
WITH NCCIH.

86
00:03:20,800 --> 00:03:25,600
THAT PRESENTATION WILL THEN BE

87
00:03:25,600 --> 00:03:28,800
FOLLOWED BY ANOTHER PRESENTATION

88
00:03:28,800 --> 00:03:31,320
BY DR. LANGEVIN RESTORING WHOLE

89
00:03:31,320 --> 00:03:32,600
JOINT HEALTH, FOLLOWING THAT

90
00:03:32,600 --> 00:03:34,040
REQUIRED TRIENNIAL REPORT ON

91
00:03:34,040 --> 00:03:35,160
CLINICAL STUDIES AND

92
00:03:35,160 --> 00:03:38,400
REPRESENTATION OF GENDER, RACE,

93
00:03:38,400 --> 00:03:39,920
AND MINORITIES, PRESENTED BY DR.

94
00:03:39,920 --> 00:03:55,480
ROBIN  BOINEAU, AND A CONCEPT

95
00:03:55,480 --> 00:03:57,320
CLEARANCE ON HIGH PRIORITY PAIN

96
00:03:57,320 --> 00:03:57,640
RESEARCH.

97
00:03:57,640 --> 00:03:59,800
COUNCIL MEMBERS RECEIVED A COPY

98
00:03:59,800 --> 00:04:05,480
OF THE SEPTEMBER 2021 MEETING 

99
00:04:05,480 --> 00:04:08,320
MINUTES, VIA ELECTRONIC COUNCIL

100
00:04:08,320 --> 00:04:08,520
BOOK.

101
00:04:08,520 --> 00:04:13,240
I LIKE TO FINAL MIZE MINUTES, TO

102
00:04:13,240 --> 00:04:14,720
SEE WHETHER THERE ARE

103
00:04:14,720 --> 00:04:16,040
CORRECTIONS TO THE FINAL COUNCIL

104
00:04:16,040 --> 00:04:17,760
MEETING MINUTES.

105
00:04:17,760 --> 00:04:18,720
IF ANYONE HAS A CORRECTION,

106
00:04:18,720 --> 00:04:22,840
PLEASE LET ME KNOW NOW BY

107
00:04:22,840 --> 00:04:29,680
RAISING YOUR HAND AND WE'LL 

108
00:04:29,680 --> 00:04:30,520
ENTER THAT.

109
00:04:30,520 --> 00:04:35,080
I WANT TO ASK FOR APPROVAL OF

110
00:04:35,080 --> 00:04:35,960
THE MINUTES.

111
00:04:35,960 --> 00:04:37,480
>> SO MOVED.

112
00:04:37,480 --> 00:04:40,200
>> AND A SECOND.

113
00:04:40,200 --> 00:04:40,520
>> SECOND.

114
00:04:40,520 --> 00:04:41,760
>> ANY FINAL QUESTIONS OR

115
00:04:41,760 --> 00:04:42,920
COMMENTS OR DISCUSSION ABOUT THE

116
00:04:42,920 --> 00:04:47,920
APPROVAL OF THE MEETING MINUTES?

117
00:04:47,920 --> 00:04:49,400
SEEING NO HANDS RAISED OR

118
00:04:49,400 --> 00:04:50,440
HEARING QUESTIONS, WE'LL GO

119
00:04:50,440 --> 00:04:55,080
AHEAD FOR A VOTE BY COUNCIL.

120
00:04:55,080 --> 00:04:57,160
YOU'LL SEE ON YOUR SCREENS A

121
00:04:57,160 --> 00:05:00,760
POLL, ENABLING YOU TO VOTE, YES

122
00:05:00,760 --> 00:05:03,800
MEANS YOU'RE APPROVING THE

123
00:05:03,800 --> 00:05:05,000
SEPTEMBER 2021 COUNCIL MEETING

124
00:05:05,000 --> 00:05:06,920
MINUTES, NO MEANS YOU'RE NOT, OR

125
00:05:06,920 --> 00:05:09,560
YOU CAN ABSTAIN.

126
00:05:09,560 --> 00:05:11,320
 

127
00:05:11,320 --> 00:05:13,240
LET'S GIVE A FEW MORE SECONDS.

128
00:05:13,240 --> 00:05:17,240
I SEE WE NOW HAVE UNANIMOUS

129
00:05:17,240 --> 00:05:22,920
APPROVAL, ONE ABSTENTION. 

130
00:05:22,920 --> 00:05:23,760
SO MINUTES ARE APPROVED.

131
00:05:23,760 --> 00:05:25,040
THANK YOU VERY MUCH.

132
00:05:25,040 --> 00:05:27,320
I WANT TO NOTE THAT FUTURE

133
00:05:27,320 --> 00:05:30,920
COUNCIL MEETING DATES ARE NOTED

134
00:05:30,920 --> 00:05:32,200
ON THE AGENDA.

135
00:05:32,200 --> 00:05:33,880
THE NEXT MEETING OF THIS

136
00:05:33,880 --> 00:05:36,600
ADVISORY COUNCIL WILL BE ON

137
00:05:36,600 --> 00:05:37,720
FRIDAY, MAY 13, 2022.

138
00:05:37,720 --> 00:05:39,840
IT IS CURRENTLY SCHEDULED TO BE

139
00:05:39,840 --> 00:05:42,200
HELD VIRTUALLY USING THE SAME

140
00:05:42,200 --> 00:05:43,720
FORMAT THAT WE'RE DOING TODAY'S

141
00:05:43,720 --> 00:05:44,360
MEETING ON.

142
00:05:44,360 --> 00:05:48,120
IF THERE IS ANY CHANGE FROM THIS

143
00:05:48,120 --> 00:05:49,680
VIRTUAL FORMAT WE'LL INFORM

144
00:05:49,680 --> 00:05:52,080
COUNCIL MEMBERS AND THE PUBLIC,

145
00:05:52,080 --> 00:05:54,240
ANNOUNCED AS POSSIBLE.

146
00:05:54,240 --> 00:05:55,440
WE ALSO REQUEST COUNCIL MEMBERS

147
00:05:55,440 --> 00:05:57,960
LET US KNOW IN ADVANCE, IF FOR

148
00:05:57,960 --> 00:05:59,680
SOME REASON YOU'RE UNABLE TO

149
00:05:59,680 --> 00:06:02,520
ATTEND ALL OR A PORTION OF THE

150
00:06:02,520 --> 00:06:03,080
COUNCIL MEETING.

151
00:06:03,080 --> 00:06:07,120
I'M NOW GOING TO GO AHEAD AND

152
00:06:07,120 --> 00:06:12,280
SHARE MY SCREEN SO THAT WE CAN

153
00:06:12,280 --> 00:06:16,440
DO THE REQUIRED REVIEW AND VOTE

154
00:06:16,440 --> 00:06:18,520
ON APPROVAL OF THE COUNCIL

155
00:06:18,520 --> 00:06:19,600
OPERATING PROCEDURES.

156
00:06:19,600 --> 00:06:21,560
SO FOR THE PUBLIC, THESE ARE

157
00:06:21,560 --> 00:06:23,440
LITERALLY THE OPERATING

158
00:06:23,440 --> 00:06:24,440
PROCEDURES THAT THIS COUNCIL

159
00:06:24,440 --> 00:06:25,600
OPERATES UNDER.

160
00:06:25,600 --> 00:06:28,360
IT IS GOVERNED BY FEDERAL LAW,

161
00:06:28,360 --> 00:06:29,720
REGULATION, AND POLICY.

162
00:06:29,720 --> 00:06:31,880
WE'RE REQUIRED ANNUALLY TO DO

163
00:06:31,880 --> 00:06:34,720
THIS TO HAVE A REVIEW AND THEN A

164
00:06:34,720 --> 00:06:39,320
FORMAL VOTE BY COUNCIL ON THE

165
00:06:39,320 --> 00:06:42,040
OPERATING PROCEDURES THEMSELVES.

166
00:06:42,040 --> 00:06:43,520
SO, AS I JUST SAID, WE'RE

167
00:06:43,520 --> 00:06:45,440
REQUIRED TO DO THIS.

168
00:06:45,440 --> 00:06:48,320
IT'S PART OF THE CHARTER FOR

169
00:06:48,320 --> 00:06:50,120
THIS ADVISORY COUNCIL, WHICH IS

170
00:06:50,120 --> 00:06:54,040
POSTED ON THE NCCIH WEBSITE.

171
00:06:54,040 --> 00:06:55,160
SO THE OPERATING PROCEDURES

172
00:06:55,160 --> 00:06:58,240
COVER REALLY FOUR GENERAL AREAS.

173
00:06:58,240 --> 00:07:00,640
THERE'S A SECTION ON REPORTS TO

174
00:07:00,640 --> 00:07:01,080
COUNCIL.

175
00:07:01,080 --> 00:07:03,200
AND THAT WILL LITERALLY BE THE

176
00:07:03,200 --> 00:07:06,080
NEXT THING ONCE WE COMPLETE THIS

177
00:07:06,080 --> 00:07:07,920
APPROVAL PROCESS FOR OUR

178
00:07:07,920 --> 00:07:10,000
OPERATING PROCEDURES, WILL BE A

179
00:07:10,000 --> 00:07:12,080
REPORT BY DR. LANGEVIN TALKING

180
00:07:12,080 --> 00:07:13,520
TO COUNCIL ABOUT VARIOUS THINGS

181
00:07:13,520 --> 00:07:14,720
OF IMPORTANCE.

182
00:07:14,720 --> 00:07:16,880
THERE WAS A SECONDARY REVIEW OF

183
00:07:16,880 --> 00:07:17,960
GRANT APPLICATIONS WHICH WE

184
00:07:17,960 --> 00:07:20,720
ALREADY CONCLUDED IN THE CLOSED

185
00:07:20,720 --> 00:07:22,480
SESSION EARLIER THIS MORNING.

186
00:07:22,480 --> 00:07:25,400
IT COVERS CONCEPT CLEARANCES FOR

187
00:07:25,400 --> 00:07:27,040
RESEARCH INITIATIVES.

188
00:07:27,040 --> 00:07:31,200
ALSO COVERS ANY ADJUDICATION OF

189
00:07:31,200 --> 00:07:32,520
APPEALS BY APPLICANT

190
00:07:32,520 --> 00:07:33,280
ORGANIZATIONS OF THEIR

191
00:07:33,280 --> 00:07:36,080
SCIENTIFIC REVIEW.

192
00:07:36,080 --> 00:07:38,880
OF THEIR GRANT APPLICATION.

193
00:07:38,880 --> 00:07:40,600
AND TOPICS ON POLICIES AND

194
00:07:40,600 --> 00:07:42,480
RESEARCH PRIORITIES AND I'LL

195
00:07:42,480 --> 00:07:48,080
SPEAK ON THESE FIVE AREAS.

196
00:07:48,080 --> 00:07:52,640
NCCIH WILL INFORM COUNCIL OF

197
00:07:52,640 --> 00:07:53,960
CURRENT SCIENTIFIC, BUDGETARY OR

198
00:07:53,960 --> 00:07:55,160
LEGISLATIVE ISSUES AND

199
00:07:55,160 --> 00:07:56,720
SIGNIFICANT CHANGES TO NCCI

200
00:07:56,720 --> 00:07:59,320
HICKS AND/OR NIH, THIS INCLUDES

201
00:07:59,320 --> 00:08:09,920
PERSONNEL CHANGES,  DR. LANGEVIN

202
00:08:09,920 --> 00:08:14,080
WILL W ILL GO OVER THAT.

203
00:08:14,080 --> 00:08:17,880
THERE ARE SIX AREAS THAT FALL IN

204
00:08:17,880 --> 00:08:19,520
THE SECOND REVIEW APPLICATIONS,

205
00:08:19,520 --> 00:08:20,920
GRANT APPLICATIONS HAVE NO

206
00:08:20,920 --> 00:08:21,840
SPECIAL CONCERNS, THERE ARE

207
00:08:21,840 --> 00:08:24,160
GRANTS THAT NEED SOME SORT OF

208
00:08:24,160 --> 00:08:25,200
SPECIAL CONSIDERATION, THERE ARE

209
00:08:25,200 --> 00:08:26,920
VARIOUS OPTIONS THAT ARE

210
00:08:26,920 --> 00:08:28,800
AVAILABLE TO COUNCIL, THERE ARE

211
00:08:28,800 --> 00:08:31,120
ALSO ADMINISTRATIVE DECISIONS

212
00:08:31,120 --> 00:08:32,520
AND ACTIONS THAT STAFF CAN TAKE

213
00:08:32,520 --> 00:08:34,520
SUBSEQUENT TO A GIVEN COUNCIL

214
00:08:34,520 --> 00:08:38,920
MEETING, THIS INCLUDES AS WELL 

215
00:08:38,920 --> 00:08:41,080
THE EXPEDITED EN BLOC

216
00:08:41,080 --> 00:08:41,840
CONCURRENCE PROCESS AND

217
00:08:41,840 --> 00:08:43,000
EXCEPTIONAL SITUATIONS.

218
00:08:43,000 --> 00:08:46,520
I'LL TALK ABOUT THESE SIX AREAS.

219
00:08:46,520 --> 00:08:49,920
GRANT APPLICATIONS SUBMITTED TO

220
00:08:49,920 --> 00:08:51,240
NCCIH WITH NO SPECIAL CONCERNS,

221
00:08:51,240 --> 00:08:54,080
THEY MAY BE IMPROVED BY WHAT WE

222
00:08:54,080 --> 00:08:56,400
CALL EN BLOC PROCESS, LITERALLY

223
00:08:56,400 --> 00:08:58,800
THAT MEANS ALL TOGETHER.

224
00:08:58,800 --> 00:09:00,720
THESE APPLICATIONS MUST BE

225
00:09:00,720 --> 00:09:02,920
RELEVANT TO MISSION OF THE

226
00:09:02,920 --> 00:09:04,960
NCCIH, CANNOT HAVE CONCERNS

227
00:09:04,960 --> 00:09:08,920
RELEVANT TO HUMAN PARTICIPANTS,

228
00:09:08,920 --> 00:09:13,840
ANIMAL SUBJECTS, BIOHAZARDS OR

229
00:09:13,840 --> 00:09:15,720
INCLUSION ISSUES, MUST BE

230
00:09:15,720 --> 00:09:16,560
DOMESTIC ISSUES, MEANING

231
00:09:16,560 --> 00:09:17,200
APPLICANT ORGANIZATION MUST BE

232
00:09:17,200 --> 00:09:18,520
BASED IN THE UNITED STATES.

233
00:09:18,520 --> 00:09:20,280
ANOTHER WAY OF SAYING THAT,

234
00:09:20,280 --> 00:09:24,280
CAN'T BE FROM A FOREIGN

235
00:09:24,280 --> 00:09:24,560
APPLICANT.

236
00:09:24,560 --> 00:09:25,240
NO APPEALS PENDING.

237
00:09:25,240 --> 00:09:27,720
IF THOSE ARE MET IT CAN GO

238
00:09:27,720 --> 00:09:31,240
FORWARD FOR EN BLOC

239
00:09:31,240 --> 00:09:31,680
CONSIDERATION.

240
00:09:31,680 --> 00:09:32,560
SOME GRANTS NEED SPECIAL

241
00:09:32,560 --> 00:09:34,320
CONSIDERATION BY COUNCIL.

242
00:09:34,320 --> 00:09:36,040
THESE INCLUDE WHEN A GIVEN

243
00:09:36,040 --> 00:09:39,320
APPLICATION THAT BE NOMINATED BY

244
00:09:39,320 --> 00:09:42,280
STAFF OR COUNCIL FOR HIGH OR LOW

245
00:09:42,280 --> 00:09:43,480
PROGRAM PRIORITY, OR GIVEN

246
00:09:43,480 --> 00:09:44,760
APPLICATION DOES HAVE CONCERNS

247
00:09:44,760 --> 00:09:47,080
RELATED TO HUMAN SUBJECTS,

248
00:09:47,080 --> 00:09:48,520
ANIMALS, BIOHAZARDS, OR THERE

249
00:09:48,520 --> 00:09:49,880
ARE ISSUES REGARDING INCLUSION

250
00:09:49,880 --> 00:09:53,080
OF WOMEN, CHILDREN, AND/OR

251
00:09:53,080 --> 00:09:54,160
MINORITIES.

252
00:09:54,160 --> 00:09:55,720
IF THE APPLICATION IS FOREIGN OR

253
00:09:55,720 --> 00:09:57,400
IF THERE'S AN APPEALS SUBMITTED

254
00:09:57,400 --> 00:09:58,520
BY THE APPLICANT ORGANIZATION.

255
00:09:58,520 --> 00:10:01,320
ALL OF THESE ARE THINGS THAT

256
00:10:01,320 --> 00:10:06,480
TRIGGER SPECIAL CONSIDERATION BY

257
00:10:06,480 --> 00:10:07,120
COUNCIL.

258
00:10:07,120 --> 00:10:08,640
FINALLY, THERE'S AN AREA CALLED

259
00:10:08,640 --> 00:10:12,920
SPECIAL COUNCIL REVIEW FOR

260
00:10:12,920 --> 00:10:14,480
APPLICATIONS FROM PRINCIPAL

261
00:10:14,480 --> 00:10:16,760
INVESTIGATORS OR PROJECT

262
00:10:16,760 --> 00:10:17,760
DIRECTORS WITH GREATER THAN $2

263
00:10:17,760 --> 00:10:19,080
MILLION TOTAL COST OF SUPPORT.

264
00:10:19,080 --> 00:10:21,720
I WANT TO NOTE FOR COUNCIL

265
00:10:21,720 --> 00:10:24,880
BECAUSE THIS IS A CHANGE FROM

266
00:10:24,880 --> 00:10:26,840
THE PRIOR COUNCIL YEARS

267
00:10:26,840 --> 00:10:28,760
OPERATING PROCEDURES, AND THIS

268
00:10:28,760 --> 00:10:32,200
IS A CHANGE THAT BEING

269
00:10:32,200 --> 00:10:33,080
IMPLEMENTED ACTUALLY FEDERALLY

270
00:10:33,080 --> 00:10:35,720
WIDE ACROSS ALL FEDERAL

271
00:10:35,720 --> 00:10:38,520
AGENCIES, INCLUDING NIH.

272
00:10:38,520 --> 00:10:40,400
PRIOR DESIGNATION USED TO BE

273
00:10:40,400 --> 00:10:42,520
BASED ON DIRECT COST OF SUPPORT.

274
00:10:42,520 --> 00:10:44,760
IT'S NOW BEEN CHANGED FOR A

275
00:10:44,760 --> 00:10:47,720
VARIETY OF GOOD ADMINISTRATIVE

276
00:10:47,720 --> 00:10:51,320
REASONS TO INTERNAL COSTS AND

277
00:10:51,320 --> 00:10:54,080
WHICH NOW INCLUDES THE DIRECT

278
00:10:54,080 --> 00:10:55,320
AND INDIRECT COSTS.

279
00:10:55,320 --> 00:10:57,800
WHEN COUNCIL IS VOTING ON

280
00:10:57,800 --> 00:11:00,000
APPLICATIONS THEY BASICALLY HAVE

281
00:11:00,000 --> 00:11:01,520
SIX DIFFERENT OPTIONS THAT THEY

282
00:11:01,520 --> 00:11:03,760
CAN TAKE.

283
00:11:03,760 --> 00:11:06,720
THEY CAN CONCUR WITH THE

284
00:11:06,720 --> 00:11:09,560
RECOMMENDATIONS AND ASSESSMENTS

285
00:11:09,560 --> 00:11:11,200
OF SCIENTIFIC REVIEW GROUP, THIS

286
00:11:11,200 --> 00:11:13,280
IS THE METHOD MOST APPLICATIONS

287
00:11:13,280 --> 00:11:14,120
GO THROUGH.

288
00:11:14,120 --> 00:11:16,320
AN APPLICATION MAY BE DOMINATED

289
00:11:16,320 --> 00:11:19,280
AND VOTED ON FOR EITHER HIGH

290
00:11:19,280 --> 00:11:22,480
PROGRAM PRIORITY, LOW PROGRAM

291
00:11:22,480 --> 00:11:23,480
PRIORITY, OR CATCH-ALL CATEGORY

292
00:11:23,480 --> 00:11:27,280
WHICH WE CALL OTHER.

293
00:11:27,280 --> 00:11:28,480
HIGH PROGRAM PRIORITY MEANS

294
00:11:28,480 --> 00:11:30,080
COUNCIL IS REPRESENT INDICATION

295
00:11:30,080 --> 00:11:31,720
AN APPLICATION BE RAISED IN

296
00:11:31,720 --> 00:11:32,960
CONSIDERATION OF FUNDING.

297
00:11:32,960 --> 00:11:35,480
LOW PROGRAM PRIORITY IS THE

298
00:11:35,480 --> 00:11:36,440
INVERSE.

299
00:11:36,440 --> 00:11:39,200
IT'S LITERALLY BEING LOWERED IN

300
00:11:39,200 --> 00:11:41,920
CONSIDERATION FOR FUNDING.

301
00:11:41,920 --> 00:11:43,680
COUNCIL MAY DEFER A GIVEN

302
00:11:43,680 --> 00:11:44,960
APPLICATION TO THE NEXT COUNCIL

303
00:11:44,960 --> 00:11:47,680
REALM BECAUSE THEY NEED TO GET

304
00:11:47,680 --> 00:11:49,040
ADDITIONAL INFORMATION BEFORE

305
00:11:49,040 --> 00:11:51,200
THEY CAN FAIRLY CONSIDER IT.

306
00:11:51,200 --> 00:11:52,520
THEY MAY DEFER THE APPLICATION

307
00:11:52,520 --> 00:11:59,440
TO GO BACK FOR ESSENTIALLY A 

308
00:11:59,440 --> 00:12:05,320
RE-REVIEW BY SCIENTIFIC BOARD,

309
00:12:05,320 --> 00:12:06,000
DELAYED.

310
00:12:06,000 --> 00:12:07,400
COUNCIL CAN RECOMMEND CHANGES, A

311
00:12:07,400 --> 00:12:08,720
REDUCTION, THEY CAN'T RECOMMEND

312
00:12:08,720 --> 00:12:10,880
TO INCREASE SCOPE BUT CAN

313
00:12:10,880 --> 00:12:12,640
RECOMMEND TO DECREASE THE SCOPE

314
00:12:12,640 --> 00:12:15,800
AND/OR BUDGET OR THE DURATION OF

315
00:12:15,800 --> 00:12:16,520
THE SUPPORT.

316
00:12:16,520 --> 00:12:18,200
FINALLY COUNCIL HAS THE OPTION

317
00:12:18,200 --> 00:12:20,800
TO MAKE A FORMAL DESIGNATION A

318
00:12:20,800 --> 00:12:24,960
GIVEN APPLICATION IS NOT

319
00:12:24,960 --> 00:12:26,040
RECOMMENDED.

320
00:12:26,040 --> 00:12:31,440
THAT OPTION IS ESSENTIALLY --

321
00:12:31,440 --> 00:12:32,720
FORBIDS INSTITUTE FROM MAKING

322
00:12:32,720 --> 00:12:35,440
AWARD REGARDLESS OF ENTHUSIASM

323
00:12:35,440 --> 00:12:37,240
THAT THE INSTITUTE MIGHT HAVE

324
00:12:37,240 --> 00:12:39,080
FOR A GIVEN APPLICATION.

325
00:12:39,080 --> 00:12:41,920
THERE ARE CERTAIN ADMINISTRATIVE

326
00:12:41,920 --> 00:12:43,520
DECISIONS THAT STAFF MAY TAKE

327
00:12:43,520 --> 00:12:45,800
SUBSEQUENT TO A COUNCIL ROUND

328
00:12:45,800 --> 00:12:48,800
THAT DO NOT REQUIRE ANY COUNCIL

329
00:12:48,800 --> 00:12:49,720
RECOMMENDATIONS.

330
00:12:49,720 --> 00:12:51,200
THESE INCLUDE THE FOLLOWING FOUR

331
00:12:51,200 --> 00:12:51,520
THINGS.

332
00:12:51,520 --> 00:12:55,480
IF THERE'S A CHANGE OF PRINCIPAL

333
00:12:55,480 --> 00:12:56,560
INVESTIGATOR, SO THE APPLICANT

334
00:12:56,560 --> 00:12:57,880
ORGANIZATION FOR WHATEVER REASON

335
00:12:57,880 --> 00:12:59,160
WANTS TO CHANGE THE PRINCIPAL

336
00:12:59,160 --> 00:13:00,920
INVESTIGATOR, THEN STAFF HAVE

337
00:13:00,920 --> 00:13:03,280
THE AUTHORITY TO REVIEW THAT

338
00:13:03,280 --> 00:13:05,440
CHANGE, AS LONG AS THEY MAKE

339
00:13:05,440 --> 00:13:08,000
SURE THE NEW PRINCIPAL

340
00:13:08,000 --> 00:13:08,720
INVESTIGATOR HAS THE WHEREWITHAL

341
00:13:08,720 --> 00:13:11,480
TO BE THE P.I. ON THIS STUDY,

342
00:13:11,480 --> 00:13:13,440
STAFF CAN MAKE THAT

343
00:13:13,440 --> 00:13:14,200
ADMINISTRATIVE CHANGE.

344
00:13:14,200 --> 00:13:15,720
THE INVERSE OF THAT IS IF THE

345
00:13:15,720 --> 00:13:16,720
PRINCIPAL INVESTIGATOR'S GOING

346
00:13:16,720 --> 00:13:19,240
TO STAY BUT INSTITUTION IS GOING

347
00:13:19,240 --> 00:13:20,640
TO BE CHANGES, TYPICALLY A CASE

348
00:13:20,640 --> 00:13:21,880
WHEN THE PRINCIPAL INVESTIGATOR

349
00:13:21,880 --> 00:13:23,160
MOVES FROM ONE INSTITUTION TO

350
00:13:23,160 --> 00:13:26,840
THE NEXT, AND WANTS TO TAKE THE

351
00:13:26,840 --> 00:13:28,320
GRANT WITH THEM.

352
00:13:28,320 --> 00:13:30,840
IF AN APPLICATION IS BEING

353
00:13:30,840 --> 00:13:32,920
DEFERRED FOR RE-REVIEW AND

354
00:13:32,920 --> 00:13:34,120
EVERYONE INVOLVED, THE

355
00:13:34,120 --> 00:13:35,720
APPLICANT, PROGRAM STAFF, REVIEW

356
00:13:35,720 --> 00:13:38,480
STAFF, ALL AGREE IT NEEDS TO BE

357
00:13:38,480 --> 00:13:39,560
REREVIEWED FOR WHATEVER REASON

358
00:13:39,560 --> 00:13:40,480
STAFF CAN MAKE THAT

359
00:13:40,480 --> 00:13:43,640
RECOMMENDATION .

360
00:13:43,640 --> 00:13:45,040
IN THAT CASE WE TAKE THE

361
00:13:45,040 --> 00:13:48,120
APPLICATION OFF THE LIST OF

362
00:13:48,120 --> 00:13:50,080
APPLICATIONS FOR COUNCIL AND PUT

363
00:13:50,080 --> 00:13:54,000
IT ON NEXT SUBSEQUENT TO

364
00:13:54,000 --> 00:13:54,560
RE-REVIEW.

365
00:13:54,560 --> 00:13:57,120
STAFF HAVE AUTHORITY TO APPROVE

366
00:13:57,120 --> 00:13:58,920
ADMINISTRATIVE SUPPLEMENTS MADE

367
00:13:58,920 --> 00:14:01,240
TO AWARDED GRANTS.

368
00:14:01,240 --> 00:14:04,320
WE HAVE OUR PROCESS, EXPEDITED

369
00:14:04,320 --> 00:14:08,320
EN BLOC CONCURRENCE, THIS IS AS

370
00:14:08,320 --> 00:14:10,440
PER NIH POLICY, INSTITUTES MAY

371
00:14:10,440 --> 00:14:14,120
STREAMLINE THE EN BLOC

372
00:14:14,120 --> 00:14:16,160
CONCURRENCE TO EXPEDITE FUNDING

373
00:14:16,160 --> 00:14:18,120
ACTION BY THE CONCURRENCE

374
00:14:18,120 --> 00:14:18,360
PROCESS.

375
00:14:18,360 --> 00:14:20,880
ANY APPLICATIONS THAT ARE

376
00:14:20,880 --> 00:14:23,360
ELIGIBLE FOR THE EXPEDITED EN

377
00:14:23,360 --> 00:14:24,920
BLOC CONCURRENCE MUST MEET ALL

378
00:14:24,920 --> 00:14:26,560
THE FOLLOWING CRITERIA.

379
00:14:26,560 --> 00:14:27,960
FIRST, APPLICATIONS MUST HAVE

380
00:14:27,960 --> 00:14:29,960
BEEN PEER REVIEWED THROUGH USUAL

381
00:14:29,960 --> 00:14:31,480
SCIENTIFIC REVIEW PROCESS.

382
00:14:31,480 --> 00:14:34,320
AND THE PEER REVIEW MUST ASSESS

383
00:14:34,320 --> 00:14:36,120
THEM AS BEING SCIENTIFICALLY

384
00:14:36,120 --> 00:14:38,040
MERITORIOUS WHICH TRANSLATES

385
00:14:38,040 --> 00:14:41,520
INTO HAVING A CERTAIN SCORE FOR

386
00:14:41,520 --> 00:14:42,080
CONSIDERATION.

387
00:14:42,080 --> 00:14:45,920
THE APPLICATIONS FOR EXPEDITED

388
00:14:45,920 --> 00:14:48,160
EN BLOC CANNOT BE COMING FROM AN

389
00:14:48,160 --> 00:14:52,320
ORGANIZATION THAT'S  BASED IN A

390
00:14:52,320 --> 00:14:52,720
FOREIGN COUNTRY.

391
00:14:52,720 --> 00:14:58,120
THEY CAN NOT HAVE CONCERNS

392
00:14:58,120 --> 00:15:05,960
RAISED RELATED TO HUMAN, ANIMAL 

393
00:15:05,960 --> 00:15:09,560
SUBJECTS, AND SUCH APPLICATION

394
00:15:09,560 --> 00:15:11,760
ALSO FOR EXPEDITED CONCURRENCE

395
00:15:11,760 --> 00:15:18,000
ARE RELEVANT TO THE NCCIH

396
00:15:18,000 --> 00:15:18,440
MISSION.

397
00:15:18,440 --> 00:15:20,120
FOR APPLICATIONS ELIGIBLE, IT

398
00:15:20,120 --> 00:15:21,640
OCCURS 6 OR 7 WEEKS PRIOR TO

399
00:15:21,640 --> 00:15:23,480
REGULAR MEETING OF COUNCIL.

400
00:15:23,480 --> 00:15:25,520
ALL REGULAR MEMBERS OF COUNCIL

401
00:15:25,520 --> 00:15:26,880
MAY VOTE, APPLICATIONS MUST

402
00:15:26,880 --> 00:15:29,040
RECEIVE AT LEAST TWO VOTES FOR

403
00:15:29,040 --> 00:15:31,880
AND NO VOTES AGAINST THE

404
00:15:31,880 --> 00:15:32,400
CONCURRENCE.

405
00:15:32,400 --> 00:15:34,080
AND APPLICATIONS THAT THEN ARE

406
00:15:34,080 --> 00:15:35,720
CONCURRED VIA THIS PROCESS WILL

407
00:15:35,720 --> 00:15:38,120
BE ELIGIBLE FOR FUNDING

408
00:15:38,120 --> 00:15:39,240
DECISIONS BY THE DIRECTOR, THIS

409
00:15:39,240 --> 00:15:41,280
DOES NOT MEAN THEY WILL BE

410
00:15:41,280 --> 00:15:42,800
AWARDED, IT JUST MEANS THEY ARE

411
00:15:42,800 --> 00:15:45,800
NOW ELIGIBLE FOR FUNDING AND

412
00:15:45,800 --> 00:15:47,920
SUBSEQUENT PROCESSING OF THOSE

413
00:15:47,920 --> 00:15:48,360
APPLICATIONS.

414
00:15:48,360 --> 00:15:51,120
WHEN ANY ACTIONS ARE TAKEN VIA

415
00:15:51,120 --> 00:15:52,880
EXPEDITED EN BLOC CONCURRENCE

416
00:15:52,880 --> 00:15:55,400
PROCESS, THEY WILL BE

417
00:15:55,400 --> 00:15:56,480
COMMUNICATED TO COUNCIL DURING

418
00:15:56,480 --> 00:15:58,040
REGULAR MEETING AS DONE EARLIER

419
00:15:58,040 --> 00:16:00,640
TODAY IN CLOSED SESSION OF

420
00:16:00,640 --> 00:16:01,080
COUNCIL.

421
00:16:01,080 --> 00:16:03,120
THERE ARE EXCEPTIONAL SITUATIONS

422
00:16:03,120 --> 00:16:04,440
THAT MAY OCCUR.

423
00:16:04,440 --> 00:16:06,920
THE DIRECTOR HAS AUTHORITY TO

424
00:16:06,920 --> 00:16:08,480
ACT UPON ANY EXTENUATING

425
00:16:08,480 --> 00:16:11,720
CIRCUMSTANCES ASSOCIATED WITH

426
00:16:11,720 --> 00:16:12,720
THOSE EXCEPTIONS, SITUATIONS.

427
00:16:12,720 --> 00:16:14,360
AS SUCH, THE DIRECTOR MAY

428
00:16:14,360 --> 00:16:16,440
CONSULT WITH THE SUBSET OF

429
00:16:16,440 --> 00:16:19,920
COUNCIL MEMBERS TO DISCUSS THESE

430
00:16:19,920 --> 00:16:20,920
EXCEPTIONAL SITUATIONS.

431
00:16:20,920 --> 00:16:23,120
AND DECIDE TO TAKE ACTION.

432
00:16:23,120 --> 00:16:25,840
ANY ACTIONS TAKEN OUTSIDE OF THE

433
00:16:25,840 --> 00:16:27,480
REGULAR PROCESS OF COUNCIL

434
00:16:27,480 --> 00:16:29,520
RELATED TO GRANT APPLICATIONS

435
00:16:29,520 --> 00:16:31,520
WILL BE DOCUMENTED AND REPORTED

436
00:16:31,520 --> 00:16:33,600
TO COUNCIL AT THE FULL MEETING

437
00:16:33,600 --> 00:16:38,400
OF COUNCIL ON ITS NEXT REGULAR

438
00:16:38,400 --> 00:16:38,880
MEETING.

439
00:16:38,880 --> 00:16:41,040
COUNCIL HAS RESPONSIBILITY FOR

440
00:16:41,040 --> 00:16:42,240
REVIEWING AND APPROVAL CONCEPTS

441
00:16:42,240 --> 00:16:46,080
THAT COME ABOUT FOR RESEARCH

442
00:16:46,080 --> 00:16:47,280
INITIATIVES.

443
00:16:47,280 --> 00:16:49,680
CONCEPTS ORIGINATE FROM NIH

444
00:16:49,680 --> 00:16:51,040
STAFF, SCIENTIFIC COMMUNITY,

445
00:16:51,040 --> 00:16:53,160
CONSTITUENCY ORGANIZATIONS,

446
00:16:53,160 --> 00:16:55,800
AND/OR CONGRESS ITSELF.

447
00:16:55,800 --> 00:16:56,880
FOR THOSE CONCEPTS, STAFF WILL

448
00:16:56,880 --> 00:17:02,760
PREPARE A SUMMARY OF THE CONCEPT

449
00:17:02,760 --> 00:17:04,720
FOR REVIEW BY COUNCIL IN OPEN

450
00:17:04,720 --> 00:17:06,480
SESSION, WE'LL HAVE SUCH A

451
00:17:06,480 --> 00:17:10,120
CONCEPT THIS AFTERNOON FOR

452
00:17:10,120 --> 00:17:12,600
COUNCIL'S ASSESSMENT AND

453
00:17:12,600 --> 00:17:13,160
CONSIDERATION.

454
00:17:13,160 --> 00:17:15,560
COUNCIL IN CONSIDERATION OF SUCH

455
00:17:15,560 --> 00:17:17,960
CONCEPT, COUNCIL MAY RECOMMEND

456
00:17:17,960 --> 00:17:19,160
APPROVAL, MODIFICATION, DEFERRAL

457
00:17:19,160 --> 00:17:27,240
OR DISAPPROVAL OF THE CONCEPT. 

458
00:17:27,240 --> 00:17:31,480
AND IF COUNCIL DOES APPROVE IT

459
00:17:31,480 --> 00:17:34,280
MAY LEAD TO ONE OR MORE FUNDING

460
00:17:34,280 --> 00:17:35,440
OPPORTUNITY ANNOUNCEMENTS IN THE

461
00:17:35,440 --> 00:17:35,680
FUTURE.

462
00:17:35,680 --> 00:17:39,120
COUNCIL HAS A ROLE FOR BEING

463
00:17:39,120 --> 00:17:40,040
ESSENTIALLY ADJUDICATING

464
00:17:40,040 --> 00:17:40,920
APPEALS.

465
00:17:40,920 --> 00:17:43,720
THERE ARE CERTAIN CRITERIA THAT

466
00:17:43,720 --> 00:17:45,920
APPEAL MUST MEET.

467
00:17:45,920 --> 00:17:48,520
APPEAL ESSENTIALLY IS A REQUEST

468
00:17:48,520 --> 00:17:49,960
BY APPLICANT WHO DISAGREES WITH

469
00:17:49,960 --> 00:17:52,040
THE ASSESSMENT OF THEIR GRANT

470
00:17:52,040 --> 00:17:52,920
APPLICATION BY THE SCIENTIFIC

471
00:17:52,920 --> 00:17:53,520
PEER REVIEW GROUP.

472
00:17:53,520 --> 00:17:55,120
THAT IS, THEY GET A SUMMARY

473
00:17:55,120 --> 00:17:57,880
STATEMENT THEY DON'T LIKE OR

474
00:17:57,880 --> 00:18:00,040
DON'T AGREE WITH HOW THE -- WHAT

475
00:18:00,040 --> 00:18:01,520
THE PEER REVIEW GROUP ASSESSED

476
00:18:01,520 --> 00:18:04,600
IT AND WANT TO APPEAL THAT

477
00:18:04,600 --> 00:18:05,200
ASSESSMENT.

478
00:18:05,200 --> 00:18:09,320
THERE ARE CERTAIN CRITERIA THAT 

479
00:18:09,320 --> 00:18:11,240
STAFF USE TO ASCERTAIN WHETHER A

480
00:18:11,240 --> 00:18:13,280
GIVEN APPEAL IS RELEVANT OR NOT

481
00:18:13,280 --> 00:18:14,440
RELEVANT, OR CRITERIA OR

482
00:18:14,440 --> 00:18:16,280
RELEVANT OR NOT.

483
00:18:16,280 --> 00:18:17,600
RELEVANT CRITERIA WOULD BE

484
00:18:17,600 --> 00:18:20,000
FACTUAL ERRORS IN THE SUMMARY

485
00:18:20,000 --> 00:18:21,440
STATEMENT THAT MIGHT

486
00:18:21,440 --> 00:18:23,120
SIGNIFICANTLY HAVE CHANGED THE

487
00:18:23,120 --> 00:18:23,400
SCORE.

488
00:18:23,400 --> 00:18:24,640
IF THERE'S EVIDENCE AGAIN IN THE

489
00:18:24,640 --> 00:18:28,680
SUMMARY STATEMENT THAT THERE WAS

490
00:18:28,680 --> 00:18:30,120
REVIEWER BIAS OR REVIEWERS HAD

491
00:18:30,120 --> 00:18:34,080
CONFLICTS OF INTEREST OR THAT

492
00:18:34,080 --> 00:18:37,040
THE PANEL LACKED THE NECESSARY

493
00:18:37,040 --> 00:18:38,080
SCIENTIFIC EXPERTISE, ALL THESE

494
00:18:38,080 --> 00:18:38,920
WOULD BE CONSIDER RELEVANT

495
00:18:38,920 --> 00:18:41,200
CRITERIA FOR SUSTAINING APPEAL.

496
00:18:41,200 --> 00:18:42,920
NOT RELEVANT WOULD BE ERRORS OF

497
00:18:42,920 --> 00:18:44,920
OMISSION, AGAIN FROM THE SUMMARY

498
00:18:44,920 --> 00:18:46,680
STATEMENT ITSELF, OR THAT THERE

499
00:18:46,680 --> 00:18:49,280
ARE DIFFERENCES OF SCIENTIFIC

500
00:18:49,280 --> 00:18:50,240
OPINION BETWEEN THE

501
00:18:50,240 --> 00:18:50,920
INVESTIGATORS, PRINCIPAL

502
00:18:50,920 --> 00:18:52,680
INVESTIGATOR OF A GIVEN

503
00:18:52,680 --> 00:18:57,120
APPLICATION, AND SCIENTIFIC 

504
00:18:57,120 --> 00:18:57,600
REVIEW GROUP.

505
00:18:57,600 --> 00:19:01,520
SO, IF A GIVEN APPEAL MEETS THE

506
00:19:01,520 --> 00:19:03,560
ELIGIBILITY CRITERIAS, AND IF

507
00:19:03,560 --> 00:19:04,440
THEN SUBSEQUENTLY PROGRAM AND

508
00:19:04,440 --> 00:19:06,640
REVIEW STAFF THAT IS NIH PROGRAM

509
00:19:06,640 --> 00:19:08,360
REVIEW STAFF AGREE THE APPEAL IS

510
00:19:08,360 --> 00:19:11,320
JUSTIFIED, THAT IS IT DOES MEET

511
00:19:11,320 --> 00:19:12,400
THE RELEVANT CRITERIA, THEN THE

512
00:19:12,400 --> 00:19:17,280
GRANT IS DEFERRED FOR RE-REVIEW

513
00:19:17,280 --> 00:19:18,440
BEFORE COUNCIL EVEN MEETS.

514
00:19:18,440 --> 00:19:20,280
SO APPLICATION IS TAKEN OFF THE

515
00:19:20,280 --> 00:19:21,720
COUNCIL LIST OF APPLICATIONS OR

516
00:19:21,720 --> 00:19:23,200
THAT COUNCIL MEETING AND GETS

517
00:19:23,200 --> 00:19:26,920
PUT ONTO THE NEXT MEETING OF

518
00:19:26,920 --> 00:19:32,240
COUNCIL AS WELL AS UNDERGOING 

519
00:19:32,240 --> 00:19:34,160
RE-REVIEW BY SCIENTIFIC REVIEW.

520
00:19:34,160 --> 00:19:35,720
IF STAFF DISAGREED ABOUT WHETHER

521
00:19:35,720 --> 00:19:39,880
A GIVEN APPEAL IS MERITORIOUS,

522
00:19:39,880 --> 00:19:40,920
WHETHER -- THE STAFF, THAT

523
00:19:40,920 --> 00:19:42,720
APPLICATION OR APPEAL THEN GOES

524
00:19:42,720 --> 00:19:44,480
TO THE CENTER'S APPEAL OFFICER

525
00:19:44,480 --> 00:19:47,080
WHO ADJUDICATES.

526
00:19:47,080 --> 00:19:48,960
IF THE APPEAL OFFICER SUPPORTS

527
00:19:48,960 --> 00:19:51,280
THE APPEAL, THEN IT IS BROUGHT

528
00:19:51,280 --> 00:19:54,040
TO COUNCIL DURING CLOSED SESSION

529
00:19:54,040 --> 00:19:55,040
FOR COUNCIL'S CONSIDERATION AND

530
00:19:55,040 --> 00:19:58,760
ADJUDICATION OF WHETHER A 

531
00:19:58,760 --> 00:20:00,960
RE-REVIEW WOULD BE APPROPRIATE.

532
00:20:00,960 --> 00:20:04,120
IF THE APPEAL IS JUDGED BY STAFF

533
00:20:04,120 --> 00:20:06,720
TO BE INELIGIBLE, THAT IS IT

534
00:20:06,720 --> 00:20:21,800
DOES NOT MEET RELEVANT CRITERIA,

535
00:20:21,800 --> 00:20:23,320
LETTER ONLY.

536
00:20:23,320 --> 00:20:26,520
COUNCIL MAY SERVE AS RESOURCE TO

537
00:20:26,520 --> 00:20:28,800
HELP DEVELOP, RECOMMEND, SET

538
00:20:28,800 --> 00:20:30,560
POLICY AND RESEARCH PRIORITIES

539
00:20:30,560 --> 00:20:31,760
FOR NCCIH.

540
00:20:31,760 --> 00:20:34,840
WE DO THIS IN A MAJOR FASHION

541
00:20:34,840 --> 00:20:39,400
WHEN WE HAVE THE PERIODIC

542
00:20:39,400 --> 00:20:40,520
LOOKING ON SETTING UP A

543
00:20:40,520 --> 00:20:43,360
STRATEGIC PLAN WHICH WE IN THIS

544
00:20:43,360 --> 00:20:45,200
CASE COUNCIL APPROVED AND WE'VE

545
00:20:45,200 --> 00:20:50,320
BEGUN IMPLEMENTING FROM LAST

546
00:20:50,320 --> 00:20:50,520
YEAR.

547
00:20:50,520 --> 00:20:52,120
AS SUCH, I'D LIKE TO GET A

548
00:20:52,120 --> 00:20:56,240
MOTION FOR APPROVAL OF THE

549
00:20:56,240 --> 00:20:57,400
COUNCIL OPERATING PROCEDURES.

550
00:20:57,400 --> 00:20:57,960
>> SO MOVED.

551
00:20:57,960 --> 00:21:00,720
>> I NEED TO GET A SECOND.

552
00:21:00,720 --> 00:21:01,040
>> SECOND.

553
00:21:01,040 --> 00:21:01,880
>> THANK YOU.

554
00:21:01,880 --> 00:21:05,600
IS THERE ANY DISCUSSION BY ANY

555
00:21:05,600 --> 00:21:07,520
COUNCIL MEMBERS ABOUT THE

556
00:21:07,520 --> 00:21:16,440
OPERATING PROCEDURES? 

557
00:21:16,440 --> 00:21:19,840
HEARING NO QUESTIONS AND NOT

558
00:21:19,840 --> 00:21:23,520
SEEING ANY RAISED HANDS, WE'LL

559
00:21:23,520 --> 00:21:26,600
GO AHEAD AND GO FOR A VOTE.

560
00:21:26,600 --> 00:21:27,840
ON OUR SCREENS, COUNCIL MEMBERS

561
00:21:27,840 --> 00:21:29,680
WILL SEE A POLL THAT YOU CAN

562
00:21:29,680 --> 00:21:31,200
VOTE ON.

563
00:21:31,200 --> 00:21:34,480
A VOTE FOR YES MEANS YOU'RE

564
00:21:34,480 --> 00:21:35,680
VOTING TO APPROVE OPERATING

565
00:21:35,680 --> 00:21:37,400
PROCEDURES, NO MEANS YOU'RE NOT,

566
00:21:37,400 --> 00:21:39,080
OR ABSTAINING.

567
00:21:39,080 --> 00:21:41,920
AND I SEE A UNANIMOUS VOTE BY

568
00:21:41,920 --> 00:21:42,760
COUNCIL MEMBERS FOR APPROVAL SO

569
00:21:42,760 --> 00:21:44,640
THAT WILL BE ENTERED INTO THE

570
00:21:44,640 --> 00:21:47,840
RECORD. 

571
00:21:47,840 --> 00:21:51,200
THANK YOU VERY MUCH.

572
00:21:51,200 --> 00:21:55,360
I'LL STOP SHARING MY SCREEN.

573
00:21:55,360 --> 00:21:57,960
THANK YOU VERY MUCH FOR THAT

574
00:21:57,960 --> 00:21:59,520
APPROVAL.

575
00:21:59,520 --> 00:22:02,240
I WANT TO ALSO NOTE TWO

576
00:22:02,240 --> 00:22:06,360
CHANGES -- OR A CHANGE FROM THE

577
00:22:06,360 --> 00:22:09,320
PRIOR COUNCIL ROUND FOR COUNCIL

578
00:22:09,320 --> 00:22:10,080
MEETING DATES.

579
00:22:10,080 --> 00:22:13,400
SPECIFICALLY, THERE IS A DATE ON

580
00:22:13,400 --> 00:22:18,360
THE AGENDA FOR COUNCIL MEMBERS

581
00:22:18,360 --> 00:22:20,560
FOR A MEETING VIRTUALLY IN

582
00:22:20,560 --> 00:22:26,160
CLOSED SESSION ONLY IN AUGUST OF

583
00:22:26,160 --> 00:22:26,840
2022, THIS YEAR.

584
00:22:26,840 --> 00:22:29,000
YOU SHOULD HAVE RECEIVED THIS IN

585
00:22:29,000 --> 00:22:30,320
THE COUNCIL AGENDA, YOU'LL SEE

586
00:22:30,320 --> 00:22:37,240
THERE'S AN ADDED DATE FOR 

587
00:22:37,240 --> 00:22:38,280
COUNCIL MEMBERS TO MEET.

588
00:22:38,280 --> 00:22:39,720
THIS IS IN ADDITION TO REGULAR

589
00:22:39,720 --> 00:22:41,920
MEETING IN SEPTEMBER.

590
00:22:41,920 --> 00:22:43,960
THIS IS FOR COUNCIL TO ASSESS

591
00:22:43,960 --> 00:22:45,480
APPLICATIONS THAT ARE COMING IN

592
00:22:45,480 --> 00:22:53,920
THAT NEED TO BE CONSIDERED FOR

593
00:22:53,920 --> 00:22:55,520
FUNDING IN FY 22, WE HAVE A

594
00:22:55,520 --> 00:22:58,120
NUMBER OF APPLICATIONS FOR

595
00:22:58,120 --> 00:22:58,840
SPECIFIC INITIATIVES FROM NIH

596
00:22:58,840 --> 00:23:00,560
THAT NEED TO GO FOR FUNDING

597
00:23:00,560 --> 00:23:01,120
CONSIDERATION.

598
00:23:01,120 --> 00:23:01,960
WE'LL PROVIDE YOU WITH MORE

599
00:23:01,960 --> 00:23:08,360
INFORMATION BUT I WANT TO PUT 

600
00:23:08,360 --> 00:23:10,720
THIS ON YOUR CALENDARS.

601
00:23:10,720 --> 00:23:11,760
AGAIN, CLOSED SESSION ONLY

602
00:23:11,760 --> 00:23:13,240
MEETING OF COUNCIL, SO THE

603
00:23:13,240 --> 00:23:14,200
MEETING WOULD TYPICALLY BE ON

604
00:23:14,200 --> 00:23:17,280
THE ORDER OF AROUND AN HOUR TO

605
00:23:17,280 --> 00:23:17,720
HOUR-AND-A-HALF.

606
00:23:17,720 --> 00:23:19,640
WE'LL GIVE YOU THE SPECIFIC TIME

607
00:23:19,640 --> 00:23:22,120
BUT PLEASE BE AWARE OF THAT.

608
00:23:22,120 --> 00:23:23,920
THE LAST AGENDA ITEM FOR TODAY

609
00:23:23,920 --> 00:23:25,720
IS THE OPEN -- FOR THE OPEN

610
00:23:25,720 --> 00:23:28,320
SESSION OF COUNCIL IS THE PUBLIC

611
00:23:28,320 --> 00:23:29,000
COMMENT SESSION.

612
00:23:29,000 --> 00:23:31,120
BECAUSE THIS COUNCIL MEETING IS

613
00:23:31,120 --> 00:23:33,040
BEING HELD VIRTUALLY, RATHER

614
00:23:33,040 --> 00:23:34,160
THAN IN PERSON, IT'S NOT

615
00:23:34,160 --> 00:23:36,200
POSSIBLE FOR MEMBERS OF THE

616
00:23:36,200 --> 00:23:39,600
PUBLIC TO MAKE IN-PERSON

617
00:23:39,600 --> 00:23:42,680
COMMENTS WHICH WE USED TO HAVE

618
00:23:42,680 --> 00:23:43,840
AT ALL COUNCIL MEETINGS WHEN

619
00:23:43,840 --> 00:23:45,520
MEETINGS WERE HELD IN PERSON.

620
00:23:45,520 --> 00:23:47,120
AS SUCH, ANY MEMBER OF THE

621
00:23:47,120 --> 00:23:50,680
PUBLIC WHO WISHES TO MAKE A 

622
00:23:50,680 --> 00:23:53,360
PUBLIC COMMENT TO OUR COUNCIL

623
00:23:53,360 --> 00:23:54,560
MAY SEND ME YOUR WRITTEN

624
00:23:54,560 --> 00:23:56,800
COMMENTS WITHIN 15 DAYS OF THE

625
00:23:56,800 --> 00:23:58,080
CONCLUSION OF THIS MEETING.

626
00:23:58,080 --> 00:24:01,800
THIS CAN BE DONE EITHER BY

627
00:24:01,800 --> 00:24:03,960
E-MAIL OR HARD COPY LETTER.

628
00:24:03,960 --> 00:24:05,920
IF YOU MAKE SUCH A COMMENT, YOUR

629
00:24:05,920 --> 00:24:07,920
WRITTEN COMMENT SHOULD BE LESS

630
00:24:07,920 --> 00:24:09,840
THAN 700 WORDS IN LENGTH, WHICH

631
00:24:09,840 --> 00:24:13,120
IS CONSISTENT WITH ABOUT A

632
00:24:13,120 --> 00:24:15,960
FIVE-MINUTE ORAL PRESENTATION,

633
00:24:15,960 --> 00:24:18,680
WHAT HAS BEEN THE LONGSTANDING

634
00:24:18,680 --> 00:24:19,800
POLICY FOR PUBLIC COMMENTS.

635
00:24:19,800 --> 00:24:23,240
UPON RECEIPT, WRITTEN COMMENTS

636
00:24:23,240 --> 00:24:26,320
WOULD BE ADDED TO THE ELECTRONIC

637
00:24:26,320 --> 00:24:28,880
COUNCIL BOOK VIA THE COUNCIL

638
00:24:28,880 --> 00:24:30,760
REVIEW SO COUNCIL MEMBERS WILL

639
00:24:30,760 --> 00:24:33,520
BE ABLE TO VIEW COMMENTS

640
00:24:33,520 --> 00:24:33,760
DIRECTLY.

641
00:24:33,760 --> 00:24:37,640
AND THAT CONCLUDES MY OPENING

642
00:24:37,640 --> 00:24:37,960
REMARKS.

643
00:24:37,960 --> 00:24:42,480
DR. LANGEVIN, PLEASE, IT'S YOUR 

644
00:24:42,480 --> 00:24:42,800
FLOOR.

645
00:24:42,800 --> 00:24:44,400
>> THANK YOU VERY MUCH.

646
00:24:44,400 --> 00:24:49,920
IT'S MY GREAT PLEASURE NOW TO

647
00:24:49,920 --> 00:24:51,680
BEGIN MY DIRECTOR'S REPORT.

648
00:24:51,680 --> 00:24:59,680
LET ME SHARE MY SCREEN.

649
00:24:59,680 --> 00:25:02,760
VOILA, CAN YOU SEE IT?

650
00:25:02,760 --> 00:25:02,960
GREAT.

651
00:25:02,960 --> 00:25:05,400
SO, IT'S MY GREAT PLEASURE TO

652
00:25:05,400 --> 00:25:10,080
START BY WELCOMING THREE NEW

653
00:25:10,080 --> 00:25:13,920
COUNCIL MEMBERS. 

654
00:25:13,920 --> 00:25:21,560
FIRST ONE IS DR. NADIA CECH,

655
00:25:21,560 --> 00:25:25,720
UNIVERSITY OF NORTH CAROLINA

656
00:25:25,720 --> 00:25:29,200
GREENS ROW, PROVIDES DYNAMIC

657
00:25:29,200 --> 00:25:32,600
RESEARCH GROUP ENGAGED IN

658
00:25:32,600 --> 00:25:33,800
DEVELOPING MASS SPECTROMETRY

659
00:25:33,800 --> 00:25:35,440
METABOLOMICS TO SOLVE

660
00:25:35,440 --> 00:25:36,320
CHALLENGING PROBLEMS IN NATURAL

661
00:25:36,320 --> 00:25:37,280
PRODUCTS RESEARCH.

662
00:25:37,280 --> 00:25:40,920
A MAJOR FOCUS OF THIS WORK IS

663
00:25:40,920 --> 00:25:42,040
DEVELOPING NOVEL METHODOLOGIES

664
00:25:42,040 --> 00:25:44,000
TO IDENTIFY COMBINATIONS OF

665
00:25:44,000 --> 00:25:47,600
MOLECULES THAT INTERACT TO

666
00:25:47,600 --> 00:25:49,760
ACHIEVE BIOLOGICAL EFFECTS,

667
00:25:49,760 --> 00:25:51,200
SYNERGY OR ANTAGONISM.

668
00:25:51,200 --> 00:25:55,280
A PRINCIPAL INVESTIGATOR FOR THE

669
00:25:55,280 --> 00:25:57,320
NCCIH AND ODS-FUNDED CENTER FOR

670
00:25:57,320 --> 00:25:58,200
HIGH CONTENT FUNCTIONAL

671
00:25:58,200 --> 00:25:59,960
ANNOTATION OF NATURAL PRODUCTS

672
00:25:59,960 --> 00:26:04,880
AND CO-DIRECTOR OF THE

673
00:26:04,880 --> 00:26:08,800
ANALYTICAL CORE FOR ENTER OF

674
00:26:08,800 --> 00:26:10,200
EXCELLENCE FOR NATURAL PRODUCTS

675
00:26:10,200 --> 00:26:18,720
AND DRUG INTERACTION.

676
00:26:18,720 --> 00:26:19,840
WELCOME.

677
00:26:19,840 --> 00:26:25,600
NEXT NEW COUNCIL MEMBER IS LORI

678
00:26:25,600 --> 00:26:28,400
KNUTSON, WHOLE HEALTH INSTITUTE.

679
00:26:28,400 --> 00:26:31,200
PRIOR TO THIS, SHE WAS ASSOCIATE

680
00:26:31,200 --> 00:26:33,760
VICE PRESIDENT FOR HEALTH AND

681
00:26:33,760 --> 00:26:36,520
WELL-BEING AT DUKE UNIVERSITY

682
00:26:36,520 --> 00:26:38,120
HEALTH SYSTEMS, EXECUTIVE

683
00:26:38,120 --> 00:26:39,440
DIRECTOR OF DUKE INTEGRATIVE

684
00:26:39,440 --> 00:26:39,880
MEDICINE.

685
00:26:39,880 --> 00:26:42,360
SHE ALSO SERVED AS DIRECTOR OF

686
00:26:42,360 --> 00:26:44,040
DUKE LEADERSHIP PROGRAMMING

687
00:26:44,040 --> 00:26:45,760
HEALTH AND WELL-BEING.

688
00:26:45,760 --> 00:26:52,480
SHE WAS FOUNDING EXECUTIVE 

689
00:26:52,480 --> 00:26:55,360
DIRECTOR OF THE GEORGE INSTITUTE

690
00:26:55,360 --> 00:26:56,640
IN MINNEAPOLIS, AND AT THE TIME

691
00:26:56,640 --> 00:27:00,120
THIS WAS NAMED AS LARGEST AND

692
00:27:00,120 --> 00:27:00,760
MOST COMPREHENSIVE INTEGRATIVE

693
00:27:00,760 --> 00:27:05,000
HEALTH PROGRAM IN THE UNITED

694
00:27:05,000 --> 00:27:05,640
STATES.

695
00:27:05,640 --> 00:27:07,320
SHE WAS INSTRUMENTAL IN

696
00:27:07,320 --> 00:27:09,360
INFRASTRUCTURE AND DATABASE

697
00:27:09,360 --> 00:27:11,120
DEVELOPMENT THAT LED TO

698
00:27:11,120 --> 00:27:15,600
MULTI-MILLION NIH GRANT TO STUDY

699
00:27:15,600 --> 00:27:17,720
INTEGRATIVE PAIN MANAGEMENT IN

700
00:27:17,720 --> 00:27:20,200
CARE SETTINGS.

701
00:27:20,200 --> 00:27:26,120
NEXT COUNCIL MEMBER IS DR. HELEN

702
00:27:26,120 --> 00:27:31,360
LAVRETSKY, DEPARTMENT OF

703
00:27:31,360 --> 00:27:33,320
INDUSTRY, UCLA, GERIATRIC

704
00:27:33,320 --> 00:27:36,480
INTEGRATIVE PSYCHIATRIST, 

705
00:27:36,480 --> 00:27:37,960
RESEARCH PROGRAM IN GERIATRIC

706
00:27:37,960 --> 00:27:38,680
DEPRESSION AND INTEGRATIVE

707
00:27:38,680 --> 00:27:42,320
MENTAL HEALTH FUNDED BY NIMH,

708
00:27:42,320 --> 00:27:45,880
PCORI, DEPARTMENT OF DEFENSE,

709
00:27:45,880 --> 00:27:46,080
NCCIH.

710
00:27:46,080 --> 00:27:49,360
USING MIND/BODY INTERVENTION

711
00:27:49,360 --> 00:27:52,040
SUCH AS YOGA, MEDICATION, TAI

712
00:27:52,040 --> 00:27:54,720
CHI, SHE'S DIRECTOR OF RESEARCH

713
00:27:54,720 --> 00:27:56,920
FOR UCLA COLLABORATIVE AND

714
00:27:56,920 --> 00:27:58,320
INTEGRATIVE MEDICINE, HER

715
00:27:58,320 --> 00:28:02,280
CURRENT RESEARCH STUDIES INCLUDE

716
00:28:02,280 --> 00:28:04,320
INVESTIGATIONS OF BIOMARKERS,

717
00:28:04,320 --> 00:28:07,120
BIOMARKERS OF RESPONSES TO

718
00:28:07,120 --> 00:28:09,240
MIND-BODY INTERVENTION FOR

719
00:28:09,240 --> 00:28:10,440
GERIATRIC DEPRESSION, MILD

720
00:28:10,440 --> 00:28:11,840
COGNITIVE IMPAIRMENT, USE OF TAI

721
00:28:11,840 --> 00:28:13,600
CHI AND YOGA FOR TREATMENT AND

722
00:28:13,600 --> 00:28:16,320
PREVENTION OF LATE LIFE MOOD AND

723
00:28:16,320 --> 00:28:17,880
COGNITIVE DISORDERS.

724
00:28:17,880 --> 00:28:23,280
SO WELCOME TO OUR NEW COUNCIL

725
00:28:23,280 --> 00:28:25,680
MEMBERS. 

726
00:28:25,680 --> 00:28:29,920
I'LL NOW SHARE SOME NEWS.

727
00:28:29,920 --> 00:28:34,400
THE FIRST BIG NEWS AT NIH IS

728
00:28:34,400 --> 00:28:36,360
THAT DR. FRANCIS COLLINS HAS

729
00:28:36,360 --> 00:28:41,160
STEPPED DOWN AS NIH DIRECTOR ON

730
00:28:41,160 --> 00:28:42,360
SEPTEMBER 19, 2021, AFTER MORE

731
00:28:42,360 --> 00:28:45,760
THAN 12 YEARS AT THE HELM.

732
00:28:45,760 --> 00:28:48,840
HE WAS THE 16th DIRECTOR OF

733
00:28:48,840 --> 00:28:54,320
THE NIH, THE ONLY DIRECTOR TO

734
00:28:54,320 --> 00:28:58,920
SERVE MORE THAN ONE 

735
00:28:58,920 --> 00:28:59,280
ADMINISTRATION.

736
00:28:59,280 --> 00:29:02,160
BEING APPROVED DIRECTOR, HE

737
00:29:02,160 --> 00:29:03,440
SERVED -- EXCUSE ME, BEFORE

738
00:29:03,440 --> 00:29:05,640
BEING APPROVED HE SERVED AS

739
00:29:05,640 --> 00:29:08,280
DIRECTOR OF THE NATIONAL GENOME

740
00:29:08,280 --> 00:29:11,880
RESEARCH INSTITUTE, AT NIH, FROM

741
00:29:11,880 --> 00:29:15,800
1993 TO 2008. 

742
00:29:15,800 --> 00:29:19,400
AMONG DR. COLLINS' NUMEROUS

743
00:29:19,400 --> 00:29:20,520
RECOGNITION OF ENORMOUS

744
00:29:20,520 --> 00:29:22,560
CONTRIBUTION TO SCIENCE WERE

745
00:29:22,560 --> 00:29:25,120
PRESIDENTIAL MEDAL OF FREEDOM,

746
00:29:25,120 --> 00:29:32,920
NATIONAL MEDAL OF SCIENCE, ALSO

747
00:29:32,920 --> 00:29:34,960
NOTABLY TEMPLETON PRIZE FOR

748
00:29:34,960 --> 00:29:36,680
SCIENTIFIC AND SPIRITUAL

749
00:29:36,680 --> 00:29:36,920
CURIOSITY.

750
00:29:36,920 --> 00:29:38,520
WE'LL GREATLY MISS DR. COLLINS,

751
00:29:38,520 --> 00:29:40,520
WHO REGULARLY ENTERTAINED US AT

752
00:29:40,520 --> 00:29:43,120
NIH WITH HIS WONDERFUL MUSICAL

753
00:29:43,120 --> 00:29:46,840
TALENT AND SENSE OF HUMOR AND IN

754
00:29:46,840 --> 00:29:49,760
ADDITION TO HIS OUTSTANDING

755
00:29:49,760 --> 00:29:53,280
SCIENTIFIC LEADERSHIP.

756
00:29:53,280 --> 00:29:55,040
WE'RE VERY HAPPY, HOWEVER, VERY

757
00:29:55,040 --> 00:29:57,760
FORTUNATE THAT DR. LARRY TABAK

758
00:29:57,760 --> 00:30:01,600
IS TAKING THE HELM AS ACTING

759
00:30:01,600 --> 00:30:02,480
DIRECTOR, PREVIOUSLY THE

760
00:30:02,480 --> 00:30:03,880
PRINCIPAL DEPUTY DIRECTOR AT

761
00:30:03,880 --> 00:30:07,160
NIH, SO WE KNOW THAT NIH IS IN

762
00:30:07,160 --> 00:30:15,920
EXCELLENT HANDS DURING THIS

763
00:30:15,920 --> 00:30:16,320
TRANSITION.

764
00:30:16,320 --> 00:30:20,080
OTHER DEPARTURES, DR. MICHAEL

765
00:30:20,080 --> 00:30:23,320
GOTTESMAN, AMAZINGLY HAS BEEN AT

766
00:30:23,320 --> 00:30:24,120
NIH SINCE 1976.

767
00:30:24,120 --> 00:30:27,440
HE'S BEEN PART OF THE NIH FAMILY

768
00:30:27,440 --> 00:30:29,800
FOR OVER 45 YEARS.

769
00:30:29,800 --> 00:30:31,440
MOST RECENTLY DR. GOTTESMAN

770
00:30:31,440 --> 00:30:33,840
SERVED AS NIH DEPUTY DIRECTOR

771
00:30:33,840 --> 00:30:35,600
FOR INTRAMURAL RESEARCH, AS WELL

772
00:30:35,600 --> 00:30:42,160
AS CHIEF OF LABORATORY OF CELL

773
00:30:42,160 --> 00:30:42,400
BIOLOGY.

774
00:30:42,400 --> 00:30:45,960
ALSO RETIRING IS DR. BILL RILEY

775
00:30:45,960 --> 00:30:48,160
WHO JOINED NIH IN 2005, AND HAS

776
00:30:48,160 --> 00:30:49,800
HAD MANY IMPORTANT ROLES HERE.

777
00:30:49,800 --> 00:30:52,760
HE SERVED AS DEPUTY DIRECTOR IN

778
00:30:52,760 --> 00:30:55,520
DIVISION OF AIDS AND HEALTH

779
00:30:55,520 --> 00:30:56,680
BEHAVIOR RESEARCH AT NATIONAL

780
00:30:56,680 --> 00:30:58,760
INSTITUTE OF MENTAL HEALTH,

781
00:30:58,760 --> 00:30:59,400
PROGRAM DIRECTOR OF NATIONAL

782
00:30:59,400 --> 00:31:01,400
HEART, LUNG AND BLOOD INSTITUTE,

783
00:31:01,400 --> 00:31:03,040
CHIEF OF SCIENCE AND RESEARCH

784
00:31:03,040 --> 00:31:05,440
AND TECHNOLOGY BRANCH OF THE

785
00:31:05,440 --> 00:31:08,440
NATIONAL CANCER INSTITUTE, AND

786
00:31:08,440 --> 00:31:10,840
MOST RECENTLY HAS BEEN ASSOCIATE

787
00:31:10,840 --> 00:31:11,920
DIRECTOR FOR BEHAVIORAL AND

788
00:31:11,920 --> 00:31:13,160
SOCIAL SCIENCE RESEARCH AND

789
00:31:13,160 --> 00:31:15,120
DIRECTOR OF OFFICE OF BEHAVIORAL

790
00:31:15,120 --> 00:31:16,120
AND SOCIAL SCIENCE RESEARCH FOR

791
00:31:16,120 --> 00:31:20,160
THE LAST SEVEN YEARS.

792
00:31:20,160 --> 00:31:22,920
SO WE'VE HAD AT NCCIH MANY

793
00:31:22,920 --> 00:31:24,440
OPPORTUNITIES TO COLLABORATE

794
00:31:24,440 --> 00:31:25,120
WITH DR. RILEY.

795
00:31:25,120 --> 00:31:31,640
I'M GOING TO MISS HIM. 

796
00:31:31,640 --> 00:31:34,600
NEXT IS DR. MARIA FREIRE,

797
00:31:34,600 --> 00:31:36,240
PRESIDENT AND EXECUTIVE DIRECTOR

798
00:31:36,240 --> 00:31:38,680
FOUNDATION FOR NATIONAL

799
00:31:38,680 --> 00:31:41,040
INSTITUTE OF HEALTH, FNIH.

800
00:31:41,040 --> 00:31:45,520
JUST RETIRED FROM TEN YEARS AT

801
00:31:45,520 --> 00:31:50,560
THE HELM OF FNIH, 2012 TO 2021.

802
00:31:50,560 --> 00:31:53,960
PRIOR TO FNIH SHE WAS PRESIDENT

803
00:31:53,960 --> 00:31:56,120
OF THE LASKER FOUNDATION, AND

804
00:31:56,120 --> 00:31:59,760
SHE ALSO IS A MEMBER OF THE

805
00:31:59,760 --> 00:32:01,720
ACADEMY OF MEDICINE AND COUNCIL

806
00:32:01,720 --> 00:32:05,080
OF FOREIGN RELATIONS.

807
00:32:05,080 --> 00:32:06,840
FNIH IS REALLY INSTRUMENTAL IN

808
00:32:06,840 --> 00:32:12,120
REALLY SORT OF HELPING CREATE

809
00:32:12,120 --> 00:32:14,640
AND SUSTAIN PUBLIC/PRIVATE

810
00:32:14,640 --> 00:32:18,200
PARTNERSHIPS, INCLUDING THE 

811
00:32:18,200 --> 00:32:18,640
VERY, VERY IMPORTANT

812
00:32:18,640 --> 00:32:21,720
PARTNERSHIPS IN THE COVID

813
00:32:21,720 --> 00:32:24,680
PANDEMIC IN CREATION OF ACTIV

814
00:32:24,680 --> 00:32:28,280
INITIATIVE THAT SPEARHEADED THE

815
00:32:28,280 --> 00:32:33,200
DEVELOPMENT OF MANY VACCINES,

816
00:32:33,200 --> 00:32:34,400
THERAPEUTICS, ET CETERA.

817
00:32:34,400 --> 00:32:37,920
ANOTHER BIT OF NEWS, AS MANY OF

818
00:32:37,920 --> 00:32:40,520
YOU HAVE HEARD, THE NOBEL PRIZE

819
00:32:40,520 --> 00:32:47,000
FOR MEDICINE THIS YEAR WENT TO 

820
00:32:47,000 --> 00:32:48,600
TWO INVESTIGATORS, DR.

821
00:32:48,600 --> 00:32:49,560
PATAPOUTIAN AND DR. JULIUS, WHO

822
00:32:49,560 --> 00:32:52,120
RECEIVED OF THE PRIZE FOR THEIR

823
00:32:52,120 --> 00:32:53,520
WORK IDENTIFYING RECEPTORS THAT

824
00:32:53,520 --> 00:32:55,720
ALLOWED THE BODY CELLS TO SENSE

825
00:32:55,720 --> 00:32:57,600
TEMPERATURE AND TOUCH.

826
00:32:57,600 --> 00:33:04,040
OF COURSE, SENSORY BIOLOGY  IS

827
00:33:04,040 --> 00:33:06,000
VERY IMPORTANT TO NCCIH RELATING

828
00:33:06,000 --> 00:33:09,440
TO PAIN AND INTERSECTION OF MIND

829
00:33:09,440 --> 00:33:10,600
AND BODY THERAPIES.

830
00:33:10,600 --> 00:33:13,800
NOW FOR SOME STAFF UPDATES.

831
00:33:13,800 --> 00:33:23,400
WE ARE ALL VERY SAD SHELLY

832
00:33:23,400 --> 00:33:24,320
HEADLEY RETIRED THIS PAST

833
00:33:24,320 --> 00:33:28,120
DECEMBER AFTER 35 YEARS OF

834
00:33:28,120 --> 00:33:29,640
SERVICE IN GRANTS MANAGEMENT,

835
00:33:29,640 --> 00:33:35,000
SEVERAL NIH INSTITUTES AND

836
00:33:35,000 --> 00:33:35,240
CENTERS.

837
00:33:35,240 --> 00:33:37,160
SHELLY JOINED 12 YEARS AGO, AND

838
00:33:37,160 --> 00:33:39,200
OVER THE PAST SEVEN YEARS HAS

839
00:33:39,200 --> 00:33:40,480
BEEN OUR CHIEF GRANTS MANAGEMENT

840
00:33:40,480 --> 00:33:44,280
OFFICER, SO SHE'S THE ONE WHO

841
00:33:44,280 --> 00:33:46,120
DISPATCHES THE GRANTS, LEADING A

842
00:33:46,120 --> 00:33:51,360
DEDICATE AND HIGH PERFORMING

843
00:33:51,360 --> 00:33:52,840
TEAM, OVERSEEING THE COMPLEX

844
00:33:52,840 --> 00:33:56,880
PROCESS OF GRANTS MANAGEMENT.

845
00:33:56,880 --> 00:34:00,120
SHELLEY REPRESENTED NCCIH IN THE

846
00:34:00,120 --> 00:34:02,120
ADVISORY COMMITTEE, INTERACTING

847
00:34:02,120 --> 00:34:03,800
WITH NCCIH GRANTEE INSTITUTIONS,

848
00:34:03,800 --> 00:34:05,200
WE REALLY THANK HER FROM THE

849
00:34:05,200 --> 00:34:06,440
BOTTOM OF OUR HEARTS FOR MANY

850
00:34:06,440 --> 00:34:09,160
YEARS OF SERVICE AND WISH HER

851
00:34:09,160 --> 00:34:11,320
ALL THE BEST.

852
00:34:11,320 --> 00:34:14,600
AND TAKING OVER FOR SHELLEY IS

853
00:34:14,600 --> 00:34:19,120
MISS DEBBIE CHEN WHO HAS A

854
00:34:19,120 --> 00:34:21,040
WEALTH OF EXPERIENCE, RECENTLY

855
00:34:21,040 --> 00:34:23,840
STARTED AT NCCIH, A WEALTH OF

856
00:34:23,840 --> 00:34:25,480
EXPERIENCE IN GRANTS

857
00:34:25,480 --> 00:34:26,560
MANAGESMENT, FOR SIX YEARS

858
00:34:26,560 --> 00:34:29,920
DEPUTY GRANTS MANAGEMENT OFFICER

859
00:34:29,920 --> 00:34:31,280
AT NHLBI, HEART, LUNG AND BLOOD

860
00:34:31,280 --> 00:34:31,520
INSTITUTE.

861
00:34:31,520 --> 00:34:33,840
PRIOR TO THAT DEBBIE WORKED IN

862
00:34:33,840 --> 00:34:37,920
GRANTS MANAGEMENT AT A NUMBER OF

863
00:34:37,920 --> 00:34:39,920
FEDERAL AGENCIES INCLUDING

864
00:34:39,920 --> 00:34:41,720
NATIONAL OCEANIC AND ATMOSPHERE

865
00:34:41,720 --> 00:34:42,400
ADMINISTRATION, NATIONAL

866
00:34:42,400 --> 00:34:44,920
INSTITUTES OF STANDARDS AND

867
00:34:44,920 --> 00:34:45,520
TECHNOLOGY, AND DEPARTMENT OF

868
00:34:45,520 --> 00:34:46,480
HEALTH AND HUMAN SERVICES, AS

869
00:34:46,480 --> 00:34:51,520
WELL AS GETTING HER START IN

870
00:34:51,520 --> 00:34:55,400
GRANTS MANAGEMENT AT NHGRI.

871
00:34:55,400 --> 00:35:00,000
SO PLEASE JOIN US IN WELCOMING

872
00:35:00,000 --> 00:35:00,440
DEBBIE.

873
00:35:00,440 --> 00:35:03,480
ALSO, PLEASE JOIN ME IN

874
00:35:03,480 --> 00:35:08,920
WELCOMING TWO NEW PROGRAM

875
00:35:08,920 --> 00:35:09,200
DIRECTORS.

876
00:35:09,200 --> 00:35:12,600
DR. LIZ GINEXI, DIVISION OF

877
00:35:12,600 --> 00:35:13,720
EXTRAMURAL RESEARCH, LIZ JOINS

878
00:35:13,720 --> 00:35:15,920
THE CLINICAL RESEARCH BRANCH AND

879
00:35:15,920 --> 00:35:18,960
WILL OVERSEE COMPONENTS OF NCCIH

880
00:35:18,960 --> 00:35:21,720
PORTFOLIO ON COMPLEX STUDY

881
00:35:21,720 --> 00:35:26,800
DESIGN AND METHODS INCLUDING

882
00:35:26,800 --> 00:35:35,640
COMPUTATIONAL MODELING, 

883
00:35:35,640 --> 00:35:36,240
INTERVENTION OPTIMIZATION,

884
00:35:36,240 --> 00:35:36,880
ARTIFICIAL INTELLIGENCE.

885
00:35:36,880 --> 00:35:40,160
SHE WILL SERVE AS PROJECT

886
00:35:40,160 --> 00:35:43,680
SCIENTIST FOR NIH DVA MANAGEMENT

887
00:35:43,680 --> 00:35:46,200
COORDINATING CENTER AND SUBJECT

888
00:35:46,200 --> 00:35:48,920
MATTER EXPERT FOR COMMON FUND

889
00:35:48,920 --> 00:35:51,120
BRIDGE TO ARTIFICIAL

890
00:35:51,120 --> 00:35:53,400
INTELLIGENCE PROGRAM.

891
00:35:53,400 --> 00:35:57,320
ALSO, PLEASE WELCOME DR.

892
00:35:57,320 --> 00:35:59,120
HORGUSLUOGLU, I HAVE TO KEEP

893
00:35:59,120 --> 00:36:01,600
PRACTICING HOW TO SAY HER

894
00:36:01,600 --> 00:36:03,320
WONDERFUL NAME, AS A PROGRAM

895
00:36:03,320 --> 00:36:07,680
DIRECTOR IN BASIC AND

896
00:36:07,680 --> 00:36:10,320
MECHANISTIC RESEARCH BRANCH OF

897
00:36:10,320 --> 00:36:12,920
DIVISION OF EXTRAMURAL RESEARCH,

898
00:36:12,920 --> 00:36:15,320
SHE IS COORDINATOR FOR NCCIH

899
00:36:15,320 --> 00:36:17,320
SMALL BUSINESS RESEARCH

900
00:36:17,320 --> 00:36:19,400
PROGRAMS, HER PORTFOLIO SUPPORTS

901
00:36:19,400 --> 00:36:21,800
DEVELOPMENT OF FULL-PERSON

902
00:36:21,800 --> 00:36:24,200
RESEARCH INVOLVING MULTI-SYSTEM

903
00:36:24,200 --> 00:36:25,640
INTERACTIONS AND MULTI-COMPONENT

904
00:36:25,640 --> 00:36:28,280
INTERVENTIONS WITH EMPHASIS ON

905
00:36:28,280 --> 00:36:29,000
TECHNOLOGY, DATABASE, AND

906
00:36:29,000 --> 00:36:29,680
COMPUTATIONAL METHODS

907
00:36:29,680 --> 00:36:31,720
DEVELOPMENT AS WELL AS

908
00:36:31,720 --> 00:36:33,800
DEVELOPMENT OF TECHNOLOGIES AND

909
00:36:33,800 --> 00:36:36,000
METHODS TO MONITOR OR ENHANCE

910
00:36:36,000 --> 00:36:39,400
MIND AND BODY INTERVENTIONS TO

911
00:36:39,400 --> 00:36:43,120
SMALL BUSINESS FUNDING 

912
00:36:43,120 --> 00:36:44,960
MECHANISMS.

913
00:36:44,960 --> 00:36:50,120
WE'VE BEEN RETHE VIEWING TO

914
00:36:50,120 --> 00:36:52,320
ADVANCE NEW -- RECRUITING TO

915
00:36:52,320 --> 00:36:53,280
ADVANCE NEW PROGRAMS.

916
00:36:53,280 --> 00:36:57,760
AND WE CAN CONTINUE TO WORK

917
00:36:57,760 --> 00:37:01,560
TOGETHER WITH DR. SABRI WHO

918
00:37:01,560 --> 00:37:04,320
TRANSFERRED TO NIDCD PROGRAM

919
00:37:04,320 --> 00:37:07,800
DIRECTOR -- AS PROGRAM DIRECTOR,

920
00:37:07,800 --> 00:37:12,280
OVERSEEING THE CHEMOSENSORY

921
00:37:12,280 --> 00:37:13,400
PORTFOLIO DIVISION, NATIONAL

922
00:37:13,400 --> 00:37:14,640
INSTITUTE OF DEAFNESS AND

923
00:37:14,640 --> 00:37:16,120
COMMUNICATION DISORDERS.

924
00:37:16,120 --> 00:37:18,520
DR. DAVE CLARK TRANSFERRED TO

925
00:37:18,520 --> 00:37:19,320
NATIONAL HEALTH INSTITUTE OF

926
00:37:19,320 --> 00:37:21,120
HEART, LUNG AND BLOOD INSTITUTE,

927
00:37:21,120 --> 00:37:24,320
HE'S GOING TO BE THERE, CHIEF

928
00:37:24,320 --> 00:37:25,520
IMPLEMENTATION -- CHIEF OF

929
00:37:25,520 --> 00:37:29,800
IMPLEMENTATION SCIENCE BRANCH.

930
00:37:29,800 --> 00:37:34,960
AND DR. DELLA WHITE TO NIGMS,

931
00:37:34,960 --> 00:37:35,520
CLINICAL RESEARCH STRATEGY

932
00:37:35,520 --> 00:37:37,320
COORDINATOR IN OFFICE OF THE

933
00:37:37,320 --> 00:37:37,840
DIRECTOR.

934
00:37:37,840 --> 00:37:44,120
WE WISH THEM ALL WELL. 

935
00:37:44,120 --> 00:37:50,760
ALSO, IMPORTANT NEWS, DR. ROBIN

936
00:37:50,760 --> 00:37:52,760
BOINEAU TRANSITIONED TO THE OCRA

937
00:37:52,760 --> 00:37:54,280
DIRECTOR, CONGRATULATIONS TO

938
00:37:54,280 --> 00:37:55,040
ROBIN.

939
00:37:55,040 --> 00:37:59,600
WE HAVE A FEW NCCIH STAFF

940
00:37:59,600 --> 00:38:01,760
ARRIVALS AND TRANSITIONS.

941
00:38:01,760 --> 00:38:03,240
KELLY McGILL IS NEW, A

942
00:38:03,240 --> 00:38:04,920
SCIENTIFIC PROGRAM ANALYST IN

943
00:38:04,920 --> 00:38:10,120
THE DIVISION OF EXTRAMURAL

944
00:38:10,120 --> 00:38:10,480
RESEARCH.

945
00:38:10,480 --> 00:38:14,480
HAJER TO GRANTS MANAGEMENT

946
00:38:14,480 --> 00:38:14,760
SPECIALIST.

947
00:38:14,760 --> 00:38:16,320
JAMES THOMPSON WAS WITH

948
00:38:16,320 --> 00:38:23,640
INTRAMURAL RESEARCH, NOW

949
00:38:23,640 --> 00:38:24,840
ADMINISTRATIVE OFFICER IN

950
00:38:24,840 --> 00:38:26,280
ADMINISTRATIVE OPERATIONS.

951
00:38:26,280 --> 00:38:30,440
WE ALSO HAVE SOME NEW STAFF

952
00:38:30,440 --> 00:38:42,680
ARRIVALS AND DEPARTURES IN 

953
00:38:42,680 --> 00:38:47,680
DIVISION OF INTRAMURAL RESEARCH.

954
00:38:47,680 --> 00:38:49,760
ARRIVALS AND DEPARTURES.

955
00:38:49,760 --> 00:38:55,000
AND NOW I WANT TO SAY A WORD

956
00:38:55,000 --> 00:39:02,840
ABOUT THE NIH PRAGMATIC TRIALS

957
00:39:02,840 --> 00:39:03,480
COLLABORATORY, THERE'S A FEW

958
00:39:03,480 --> 00:39:05,920
THINGS HAPPENING IN THIS AREA.

959
00:39:05,920 --> 00:39:08,920
THIS IS THE TENTH ANNIVERSARY OF

960
00:39:08,920 --> 00:39:12,680
THE COLLABORATORY, AS WE CALL

961
00:39:12,680 --> 00:39:12,920
IT.

962
00:39:12,920 --> 00:39:15,400
AND ALSO THIS YEAR MARKS A VERY

963
00:39:15,400 --> 00:39:18,040
IMPORTANT MILESTONE IN THE

964
00:39:18,040 --> 00:39:19,880
COLLABORATORY, WHICH THAT IT'S

965
00:39:19,880 --> 00:39:21,400
TRANSITIONING FROM THE COMMON

966
00:39:21,400 --> 00:39:24,160
FUND TO FUNDING BY THE NIH

967
00:39:24,160 --> 00:39:25,600
INSTITUTES AND CENTERS.

968
00:39:25,600 --> 00:39:26,840
AND SO IT SEEMED LIKE THIS IS

969
00:39:26,840 --> 00:39:29,520
GOING TO BE A GOOD OPPORTUNITY

970
00:39:29,520 --> 00:39:30,520
FOR REBRANDING.

971
00:39:30,520 --> 00:39:35,240
THE REASON FOR THAT IS BECAUSE

972
00:39:35,240 --> 00:39:39,800
THE -- WE USED TO -- THERE ARE

973
00:39:39,800 --> 00:39:40,720
SO MANY COLLABORATORIES NOW,

974
00:39:40,720 --> 00:39:44,400
THERE IS -- IT WAS STARTING TO

975
00:39:44,400 --> 00:39:49,120
BECOME CONFUSING THAT THERE'S A 

976
00:39:49,120 --> 00:39:51,320
PAIN MANAGEMENT COLLABORATORY,

977
00:39:51,320 --> 00:39:52,600
THERE'S THE IMPACT COLLABORATORY

978
00:39:52,600 --> 00:39:53,040
AT NIH.

979
00:39:53,040 --> 00:39:55,120
AND SO WE WANTED TO HAVE A NAME

980
00:39:55,120 --> 00:40:00,560
THAT WAS A LITTLE BIT MORE EASY,

981
00:40:00,560 --> 00:40:02,520
BECAUSE HEALTH CARE SYSTEMS

982
00:40:02,520 --> 00:40:03,520
RESEARCH COLLABORATORY WAS

983
00:40:03,520 --> 00:40:05,520
DIFFICULT TO REMEMBER, WANTED

984
00:40:05,520 --> 00:40:08,320
SOMETHING MORE EASY TO USE AS A

985
00:40:08,320 --> 00:40:11,680
NAME BUT ALMOST THAT REFLECTED

986
00:40:11,680 --> 00:40:14,800
THE OVERALL MISSION OF THE

987
00:40:14,800 --> 00:40:19,600
COLLABORATORY, WHICH IS TO -- IN

988
00:40:19,600 --> 00:40:20,800
THE MAIN PRAGMATIC

989
00:40:20,800 --> 00:40:23,520
COLLABORATORY, THE NAME SEEMS TO

990
00:40:23,520 --> 00:40:24,080
FIT.

991
00:40:24,080 --> 00:40:29,200
WE DEFINE PRAGMATIC TRIALS AS

992
00:40:29,200 --> 00:40:37,120
LARGE  EFFICIENT STUDIES

993
00:40:37,120 --> 00:40:37,760
ENCOMPASSING EFFECTIVENESS,

994
00:40:37,760 --> 00:40:38,600
IMPLEMENTATION, DISSEMINATION.

995
00:40:38,600 --> 00:40:41,560
WE FEEL THE NAME PRAGMATIC TRIAL

996
00:40:41,560 --> 00:40:45,920
COLLABORATORY EMBRACES ALL OF

997
00:40:45,920 --> 00:40:46,240
THAT.

998
00:40:46,240 --> 00:40:49,960
SO, AS YOU SEE HERE, THE TOPICS

999
00:40:49,960 --> 00:40:52,720
THAT THE PRAGMATIC TRIAL

1000
00:40:52,720 --> 00:40:56,320
COLLABORATORY HAS REALLY BECOME

1001
00:40:56,320 --> 00:40:57,640
EXPERTS AT EMBRACE A LOT OF

1002
00:40:57,640 --> 00:41:00,560
ISSUES FIRST AND FOREMOST IN

1003
00:41:00,560 --> 00:41:03,360
PEOPLE'S MINDS IN TERMS OF

1004
00:41:03,360 --> 00:41:05,320
PERFORMING IMPACTFUL CLINICAL

1005
00:41:05,320 --> 00:41:08,080
RESEARCH SUCH AS STUDIES

1006
00:41:08,080 --> 00:41:11,280
DESIGNED WITH INPUT FROM HEALTH

1007
00:41:11,280 --> 00:41:13,320
SYSTEMS STAKEHOLDERS, VERY

1008
00:41:13,320 --> 00:41:13,840
IMPORTANT.

1009
00:41:13,840 --> 00:41:16,600
INTERVENTIONS THAT CAN BE

1010
00:41:16,600 --> 00:41:19,320
INCORPORATED INTO THE ROUTINE

1011
00:41:19,320 --> 00:41:20,480
CLINICAL CARE, NOT RESEARCH

1012
00:41:20,480 --> 00:41:23,120
THAT'S PERFORMED IN A SETTING

1013
00:41:23,120 --> 00:41:26,240
THAT IS SEPARATE FROM CLINICAL

1014
00:41:26,240 --> 00:41:26,440
CARE.

1015
00:41:26,440 --> 00:41:27,240
DATA COLLECTED THROUGH

1016
00:41:27,240 --> 00:41:30,640
ELECTRONIC HEALTH RECORD, FOR 

1017
00:41:30,640 --> 00:41:31,800
EXAMPLE, REPRESENTING THE

1018
00:41:31,800 --> 00:41:35,560
DIVERSE AND REPRESENTATIVE SITE

1019
00:41:35,560 --> 00:41:38,360
POPULATIONS, AND OUTCOMES

1020
00:41:38,360 --> 00:41:38,640
IMPORTANT.

1021
00:41:38,640 --> 00:41:45,360
THIS IS REALLY A --

1022
00:41:45,360 --> 00:41:47,680
COLLABORATORY HAS BECOME

1023
00:41:47,680 --> 00:41:48,520
IMPORTANT HELPING CONDUCT

1024
00:41:48,520 --> 00:41:50,160
RESEARCH IN THE BEST AND MOST

1025
00:41:50,160 --> 00:41:51,040
RIGOROUS WAY.

1026
00:41:51,040 --> 00:41:56,120
JUST TO SHOW HOW THIS EVOLVED,

1027
00:41:56,120 --> 00:41:57,680
FROM 2012 TO 2017 THE

1028
00:41:57,680 --> 00:41:59,560
COLLABORATORY WAS ENTIRELY

1029
00:41:59,560 --> 00:42:02,840
FUNDED BY THE NIH COMMON FUND.

1030
00:42:02,840 --> 00:42:03,800
THIS IS FUNDED BY OFFICE OF

1031
00:42:03,800 --> 00:42:06,000
DIRECTOR AT I. NO INCLUDING

1032
00:42:06,000 --> 00:42:07,120
FUNDING FOR COORDINATING CENTER

1033
00:42:07,120 --> 00:42:09,800
AS WELL AS CORE WORKING GROUPS

1034
00:42:09,800 --> 00:42:11,760
AND DEMONSTRATION PROJECTS.

1035
00:42:11,760 --> 00:42:14,840
IT WAS A TRANSITION PERIOD WHERE

1036
00:42:14,840 --> 00:42:17,800
THE NIH INSTITUTES AND CENTERS

1037
00:42:17,800 --> 00:42:26,120
STARTED TO ASSUME SOME PARTIAL 

1038
00:42:26,120 --> 00:42:27,640
FUNDING OF COORDINATING CENTER

1039
00:42:27,640 --> 00:42:28,600
AS WELL AS DEMONSTRATION

1040
00:42:28,600 --> 00:42:29,600
PROJECTS.

1041
00:42:29,600 --> 00:42:31,680
IN 2019 THERE WAS ADDITIONAL

1042
00:42:31,680 --> 00:42:33,800
FUNDING FROM THE HEAL INITIATIVE

1043
00:42:33,800 --> 00:42:35,320
TO FUND A NUMBER OF PROJECTS IN

1044
00:42:35,320 --> 00:42:38,080
THE AREA OF PAIN, OPIOID USE

1045
00:42:38,080 --> 00:42:38,360
DISORDERS.

1046
00:42:38,360 --> 00:42:43,080
AND FINALLY NOW AS YOU CAN SEE

1047
00:42:43,080 --> 00:42:45,480
IF THE COMMON FUND IS GOING

1048
00:42:45,480 --> 00:42:46,040
AWAY.

1049
00:42:46,040 --> 00:42:47,760
UNDER LEADERSHIP OF NCCIH AND

1050
00:42:47,760 --> 00:42:49,720
NIA, CO-LEADS IN THIS, WE'VE

1051
00:42:49,720 --> 00:42:52,520
BEEN ABLE TO ASSEMBLE A GROUP OF

1052
00:42:52,520 --> 00:42:56,400
NIH INSTITUTES THAT AGREED TO

1053
00:42:56,400 --> 00:42:59,680
CONTINUE FUNDING THE ENTIRETY OF

1054
00:42:59,680 --> 00:43:01,080
THE COLLABORATORY, INCLUDING

1055
00:43:01,080 --> 00:43:02,320
COORDINATING CENTER, AS WELL AS

1056
00:43:02,320 --> 00:43:03,200
DEMONSTRATION PROJECTS.

1057
00:43:03,200 --> 00:43:10,480
SO HERE  ARE ALL THE INSTITUTES 

1058
00:43:10,480 --> 00:43:11,600
THAT AGREED TO CONTINUE,

1059
00:43:11,600 --> 00:43:12,320
NATIONAL CANCER INSTITUTE, HEART

1060
00:43:12,320 --> 00:43:18,120
LUNG  HEART, LUNG AND BLOOD,

1061
00:43:18,120 --> 00:43:20,520
MINORITY HEALTH AND HEALTH

1062
00:43:20,520 --> 00:43:22,160
DISPARITIES, NURSING, OFFICE OF

1063
00:43:22,160 --> 00:43:23,160
BEHAVIORAL AND SOCIAL SCIENCES

1064
00:43:23,160 --> 00:43:25,520
RESEARCH AND OFFICE OF DISEASE

1065
00:43:25,520 --> 00:43:29,160
PREVENTION, SO YOU CAN SEE

1066
00:43:29,160 --> 00:43:30,920
THERE'S BEEN AN IMPRESSIVE GROUP

1067
00:43:30,920 --> 00:43:32,680
OF INSTITUTES AND CENTERS THAT

1068
00:43:32,680 --> 00:43:34,640
HAVE AGREED TO CONTINUE ON.

1069
00:43:34,640 --> 00:43:36,800
THIS IS VERY IMPORTANT BECAUSE

1070
00:43:36,800 --> 00:43:43,360
THE WHOLE GOAL OF THESE COMMON

1071
00:43:43,360 --> 00:43:47,320
FUND FUND PROJECTS, THEY ARE

1072
00:43:47,320 --> 00:43:48,160
GUARANTEE.

1073
00:43:48,160 --> 00:43:49,720
IT'S TEN YEARS TYPICALLY, AFTER

1074
00:43:49,720 --> 00:43:51,240
THAT EXPECTED PROJECTS WILL

1075
00:43:51,240 --> 00:43:53,120
CONTINUE BUT NOT ALWAYS THE CASE

1076
00:43:53,120 --> 00:43:55,600
SO THIS IS A REALLY SUCCESS

1077
00:43:55,600 --> 00:43:57,720
STORY. 

1078
00:43:57,720 --> 00:44:02,160
AS FAR AS THE NEW PHASE OF THE

1079
00:44:02,160 --> 00:44:03,440
COLLABORATORY, THERE'S GOING TO

1080
00:44:03,440 --> 00:44:06,680
BE THIS AREA OF FOCUS THAT'S

1081
00:44:06,680 --> 00:44:12,760
GOING TO SHIFT TO INCLUDE

1082
00:44:12,760 --> 00:44:13,720
IMPLEMENTATION SCIENCE TRIALS,

1083
00:44:13,720 --> 00:44:16,280
THAT STUDY STRATEGIES FOR

1084
00:44:16,280 --> 00:44:17,120
IMPLEMENTING EVIDENCE-BASED

1085
00:44:17,120 --> 00:44:19,760
INTERVENTIONS INTO HEALTH CARE

1086
00:44:19,760 --> 00:44:26,000
DELIVERY SO REALLY EXTENDING THE

1087
00:44:26,000 --> 00:44:27,760
EMPHASIS FROM EFFICACY TO

1088
00:44:27,760 --> 00:44:30,480
IMPLEMENTATION, PUTTING ALL OF

1089
00:44:30,480 --> 00:44:36,400
THIS INTO THE SCOPE OF THE

1090
00:44:36,400 --> 00:44:37,600
STRUCTURE.

1091
00:44:37,600 --> 00:44:40,680
FINALLY, WE'VE ALSO ELECTED TO

1092
00:44:40,680 --> 00:44:42,160
FOCUS ON HEALTH DISPARITIES AND

1093
00:44:42,160 --> 00:44:44,160
HEALTH CARE DELIVERY AS A NEW

1094
00:44:44,160 --> 00:44:45,760
FOCUS WHICH HAS ALLOWS US TO

1095
00:44:45,760 --> 00:44:50,200
ATTRACT A LOT OF OTHER

1096
00:44:50,200 --> 00:44:51,840
INSTITUTES TO THIS EFFORT.

1097
00:44:51,840 --> 00:44:54,560
WE'RE PLEASED AT HOW THIS IS

1098
00:44:54,560 --> 00:44:55,200
EVOLVING.

1099
00:44:55,200 --> 00:45:03,880
THE NEXT THING IS GOING TO BE

1100
00:45:03,880 --> 00:45:05,280
BUDGET UPDATES.

1101
00:45:05,280 --> 00:45:09,200
THIS IS THE SAME AS WHAT I

1102
00:45:09,200 --> 00:45:11,560
SHOWED YOU BACK AT THE LAST

1103
00:45:11,560 --> 00:45:13,520
COUNCIL IN SEPTEMBER.

1104
00:45:13,520 --> 00:45:15,960
THIS ILLUSTRATES THAT IF YOU

1105
00:45:15,960 --> 00:45:19,920
LOOK HERE AT -- EXCUSE ME HERE.

1106
00:45:19,920 --> 00:45:23,640
THIS IS CUT OFF ON MY SCREEN.

1107
00:45:23,640 --> 00:45:25,040
SORRY ABOUT THAT.

1108
00:45:25,040 --> 00:45:27,120
BUT BASICALLY BOTTOM LINE IS

1109
00:45:27,120 --> 00:45:30,160
THAT WE HAVE HAD A SORT OF

1110
00:45:30,160 --> 00:45:32,240
MODEST INCREASE IN BUDGET FROM

1111
00:45:32,240 --> 00:45:33,000
2020 TO 2021.

1112
00:45:33,000 --> 00:45:34,760
WE OF COURSE DO NOT KNOW YET

1113
00:45:34,760 --> 00:45:42,360
WHAT THE BUDGET WILL BE FOR 

1114
00:45:42,360 --> 00:45:42,560
2022.

1115
00:45:42,560 --> 00:45:44,720
THE PRESIDENT'S BUDGET SUBMITTED

1116
00:45:44,720 --> 00:45:46,600
INCLUDING A RATHER LARGE

1117
00:45:46,600 --> 00:45:47,320
INCREASE, I DON'T KNOW IF YOU

1118
00:45:47,320 --> 00:45:53,000
CAN SEE AT THE BOTTOM, TO $184

1119
00:45:53,000 --> 00:45:53,480
MILLION.

1120
00:45:53,480 --> 00:45:55,120
BECAUSE WE'RE STILL IN A

1121
00:45:55,120 --> 00:45:58,040
CONTINUING RESOLUTION WE HAVE NO

1122
00:45:58,040 --> 00:46:00,480
IDEA EXACTLY WHAT THIS BUDGET

1123
00:46:00,480 --> 00:46:02,000
WILL BE.

1124
00:46:02,000 --> 00:46:05,520
BUT AN INTERESTING AND IMPORTANT

1125
00:46:05,520 --> 00:46:08,720
PART OF THIS WAS THAT THIS BILL

1126
00:46:08,720 --> 00:46:13,040
HERE THAT PROPOSED THIS INCREASE

1127
00:46:13,040 --> 00:46:15,840
FOR FY 22 INCLUDED A RATHER

1128
00:46:15,840 --> 00:46:17,560
SUBSTANTIAL INCREASE ARE $26

1129
00:46:17,560 --> 00:46:19,080
MILLION SPECIFICALLY FOR NCCIH

1130
00:46:19,080 --> 00:46:20,680
TO SUPPORT RESEARCH RELATED TO

1131
00:46:20,680 --> 00:46:24,920
MAIN  -- PAIN AND PAIN

1132
00:46:24,920 --> 00:46:25,320
MANAGEMENT.

1133
00:46:25,320 --> 00:46:26,120
WE DON'T KNOW WHETHER THIS

1134
00:46:26,120 --> 00:46:27,880
BUDGET IS GOING TO PASS.

1135
00:46:27,880 --> 00:46:30,360
WE DON'T KNOW WHETHER THIS $26

1136
00:46:30,360 --> 00:46:35,200
MILLION IS OR ISN'T GOING TO BE

1137
00:46:35,200 --> 00:46:36,720
ALLOCATED TO US.

1138
00:46:36,720 --> 00:46:39,120
WE'RE NOT ABLE TO SAY THAT RIGHT

1139
00:46:39,120 --> 00:46:41,320
NOW THIS BILL HAS PASSED IN THE

1140
00:46:41,320 --> 00:46:42,720
HOUSE, BUT NOT PASSED IN THE

1141
00:46:42,720 --> 00:46:43,920
SENATE, SO WE DON'T KNOW WHAT'S

1142
00:46:43,920 --> 00:46:45,120
GOING TO HAPPEN WITH IT.

1143
00:46:45,120 --> 00:46:47,800
HOWEVER, WE WANT TO BE

1144
00:46:47,800 --> 00:46:49,600
PREPARED,JUST IN CASE THIS DOES

1145
00:46:49,600 --> 00:46:51,920
COME OUR WAY.

1146
00:46:51,920 --> 00:46:54,040
AND BECAUSE WE'RE ALREADY

1147
00:46:54,040 --> 00:46:58,720
GETTING PRETTY ADVANCED IN 

1148
00:46:58,720 --> 00:47:00,600
FISCAL YEAR, WE WANTED TO HAVE A

1149
00:47:00,600 --> 00:47:06,000
VARIETY OF DIFFERENT OPTIONS FOR

1150
00:47:06,000 --> 00:47:08,520
SPECIFIC INITIATIVES THAT DR.

1151
00:47:08,520 --> 00:47:10,160
EMMELINE EDWARDS WILL TELL YOU

1152
00:47:10,160 --> 00:47:11,600
ABOUT AFTER MY REPORT, TELLING

1153
00:47:11,600 --> 00:47:12,720
YOU ABOUT SPECIFIC INITIATIVES

1154
00:47:12,720 --> 00:47:15,120
WE'RE PUTTING TOGETHER BOTH AT

1155
00:47:15,120 --> 00:47:17,560
NCCIH, ALSO VERY IMPORTANTLY IN

1156
00:47:17,560 --> 00:47:20,040
COLLABORATION WITH MANY OTHER OF

1157
00:47:20,040 --> 00:47:22,120
OUR COLLEAGUES AND OTHER

1158
00:47:22,120 --> 00:47:23,920
INSTITUTES AND CENTERS AT NIH AS

1159
00:47:23,920 --> 00:47:29,120
WELL AS THE HEAL INITIATIVE.

1160
00:47:29,120 --> 00:47:30,520
EMMELINE WILL TELL US ABOUT

1161
00:47:30,520 --> 00:47:30,760
THAT.

1162
00:47:30,760 --> 00:47:31,960
ANOTHER IMPORTANT EVENT THAT

1163
00:47:31,960 --> 00:47:35,040
OCCURRED, THERE WAS A

1164
00:47:35,040 --> 00:47:37,760
CONGRESSIONAL BRIEFING WITH

1165
00:47:37,760 --> 00:47:38,960
REPRESENTATIVE JACKIE WALORSKI,

1166
00:47:38,960 --> 00:47:41,520
CO-CHAIR OF THE INTEGRATIVE

1167
00:47:41,520 --> 00:47:44,120
HEALTH CAUCUS, INTERESTED IN OUR

1168
00:47:44,120 --> 00:47:45,320
WHOLE PERSON HEALTH NEW

1169
00:47:45,320 --> 00:47:46,320
STRATEGIC PLAN.

1170
00:47:46,320 --> 00:47:48,720
AND WE'RE PLANNING TO FOLLOW UP

1171
00:47:48,720 --> 00:47:52,720
ON THIS WITH THE ENTIRE CAUCUS.

1172
00:47:52,720 --> 00:47:55,240
THERE WAS A BRIEFING OF NIH

1173
00:47:55,240 --> 00:47:56,920
LEADERSHIP AND INSTITUTES AND

1174
00:47:56,920 --> 00:47:58,520
CENTERS WITH THE DEMOCRATIC

1175
00:47:58,520 --> 00:48:00,960
WOMEN'S CAUCUS, WHICH WAS ALSO

1176
00:48:00,960 --> 00:48:04,320
GENERATING A LOT OF INTEREST.

1177
00:48:04,320 --> 00:48:07,320
I NOW WANT TO TAKE A COUPLE

1178
00:48:07,320 --> 00:48:10,920
MINUTES TO REALLY THANK OUR

1179
00:48:10,920 --> 00:48:12,520
GRANTEE COMMUNITY.

1180
00:48:12,520 --> 00:48:15,720
ABOUT HOW THE RESPONSE TO THE

1181
00:48:15,720 --> 00:48:19,080
COVID-19 PANDEMIC HAS BEEN JUST

1182
00:48:19,080 --> 00:48:25,040
SO IMPRESSIVE AMONG RESEARCHERS.

1183
00:48:25,040 --> 00:48:27,240
OUR INVESTIGATORS, A HUGE HURDLE

1184
00:48:27,240 --> 00:48:28,480
WITH THE COVID-19 PANDEMIC, DID

1185
00:48:28,480 --> 00:48:30,440
NOT TREAT IT AS AN IMPOSSIBLE

1186
00:48:30,440 --> 00:48:32,840
FEAT THEY WERE UNABLE TO ADDRESS

1187
00:48:32,840 --> 00:48:34,720
BUT INSTEAD WERE THOUGHTFUL AND

1188
00:48:34,720 --> 00:48:37,840
CAREFUL IN WHAT COULD BE DONE

1189
00:48:37,840 --> 00:48:40,160
WITHIN THE FRAMEWORK OF PUTTING

1190
00:48:40,160 --> 00:48:43,720
SAFETY FIRST AND ALSO ADAPTING

1191
00:48:43,720 --> 00:48:46,080
WITHIN LIMITATIONS OF AVAILABLE

1192
00:48:46,080 --> 00:48:48,160
RESOURCES INCLUDING TIME, STAFF,

1193
00:48:48,160 --> 00:48:50,560
ACCESS TO HUMAN SUBJECTS, AND SO

1194
00:48:50,560 --> 00:48:51,120
ON.

1195
00:48:51,120 --> 00:48:52,880
SO, OUR INVESTIGATORS ASSESS

1196
00:48:52,880 --> 00:48:55,400
LANDSCAPE, CHOSE A PATH FORWARD,

1197
00:48:55,400 --> 00:48:56,920
REVISING STUDY DESIGNS WHEN

1198
00:48:56,920 --> 00:48:58,120
APPROPRIATE THAT WOULD LIKELY

1199
00:48:58,120 --> 00:49:00,640
WORK GIVEN THE PANDEMIC'S

1200
00:49:00,640 --> 00:49:00,920
CONSTRAINTS.

1201
00:49:00,920 --> 00:49:04,440
AND WE WERE VERY IMPRESSED WITH

1202
00:49:04,440 --> 00:49:09,560
PILOT TESTING AS NEEDED, PEOPLE

1203
00:49:09,560 --> 00:49:11,320
BROUGHT IN EXPERTISE AS THEY

1204
00:49:11,320 --> 00:49:12,960
REVISED APPROACHES WITH GREAT

1205
00:49:12,960 --> 00:49:14,160
DEAL OF COLLABORATION ACROSS

1206
00:49:14,160 --> 00:49:15,560
STAKEHOLDERS AND COMMUNICATIONS

1207
00:49:15,560 --> 00:49:18,120
ABOUT WHAT WAS GOING, AS THINGS

1208
00:49:18,120 --> 00:49:18,320
EVOLVED.

1209
00:49:18,320 --> 00:49:20,400
WE WERE VERY IMPRESSED WITH THE

1210
00:49:20,400 --> 00:49:21,120
RESPONSE TO THE SCIENTIFIC

1211
00:49:21,120 --> 00:49:23,000
COMMUNITY AND THANK YOU FOR YOUR

1212
00:49:23,000 --> 00:49:25,880
HARD WORK THROUGH THESE

1213
00:49:25,880 --> 00:49:30,480
DIFFICULT TIMES. 

1214
00:49:30,480 --> 00:49:32,600
REGARDING WHAT'S GOING ON AT

1215
00:49:32,600 --> 00:49:38,240
NIH, IN RESPONSE TO THE COVID

1216
00:49:38,240 --> 00:49:41,720
PANDEMIC, NIH LAUNCHED A VERY

1217
00:49:41,720 --> 00:49:43,600
IMPORTANT RECOVER INITIATIVE,

1218
00:49:43,600 --> 00:49:45,520
WHICH MEANS RESEARCHING COVID TO

1219
00:49:45,520 --> 00:49:48,520
ENHANCE RECOVERY TO LEARN WHY

1220
00:49:48,520 --> 00:49:49,480
SOME PEOPLE HAVE PROLONGED

1221
00:49:49,480 --> 00:49:52,120
SYMPTOMS REFERRED TO AS LONG

1222
00:49:52,120 --> 00:49:54,840
COVID OR DEVELOP NEW OR

1223
00:49:54,840 --> 00:50:01,200
RECURRING SYMPTOMS AFTER THE 

1224
00:50:01,200 --> 00:50:03,160
ACUTE PHASE OF INFECTION OF

1225
00:50:03,160 --> 00:50:03,920
SARS-COV-2.

1226
00:50:03,920 --> 00:50:05,880
THESE SYMPTOMS ARE TROUBLESOME

1227
00:50:05,880 --> 00:50:06,680
INCLUDING PAIN, HEADACHE,

1228
00:50:06,680 --> 00:50:08,840
FATIGUE, BRAIN FOG THAT A LOT OF

1229
00:50:08,840 --> 00:50:10,200
PEOPLE COMPLAIN ABOUT, SHORTNESS

1230
00:50:10,200 --> 00:50:12,000
OF BREATH.

1231
00:50:12,000 --> 00:50:17,040
AND SO NIH HAS PUT IN A VERY

1232
00:50:17,040 --> 00:50:19,000
LARGE EFFORT, $470 MILLION, TO

1233
00:50:19,000 --> 00:50:23,520
BUILD A NATIONAL STUDY

1234
00:50:23,520 --> 00:50:24,120
POPULATION OF DIVERSE

1235
00:50:24,120 --> 00:50:25,960
INDIVIDUALS AND SUPPORT LARGE

1236
00:50:25,960 --> 00:50:26,760
SCALE STUDIES ON LONG-TERM

1237
00:50:26,760 --> 00:50:30,520
EFFECTS OF COVID-19.

1238
00:50:30,520 --> 00:50:34,200
THE RECOVER INITIATIVE MADE

1239
00:50:34,200 --> 00:50:36,720
PARENT AWARD TO NEW YORK

1240
00:50:36,720 --> 00:50:38,160
UNIVERSITY, MAKING MULTIPLE

1241
00:50:38,160 --> 00:50:42,120
SUBAWARDS TO 100 RESEARCHERS AT

1242
00:50:42,120 --> 00:50:44,440
30 INSTITUTIONS AND SERVE AS

1243
00:50:44,440 --> 00:50:46,040
RECOVER CLINICAL SCIENCE CORE.

1244
00:50:46,040 --> 00:50:53,920
THIS MAJOR NEW AWARD TO NYI

1245
00:50:53,920 --> 00:50:55,840
LANGONE LEVERAGES LONG-RUNNING

1246
00:50:55,840 --> 00:50:59,920
COHORT STUDIES AND SO WE'RE VERY

1247
00:50:59,920 --> 00:51:00,360
INTERESTED AT NCCIH,

1248
00:51:00,360 --> 00:51:02,240
PARTICULARLY IN THE AREA OF

1249
00:51:02,240 --> 00:51:05,120
STRESS AND RECOVERY FROM

1250
00:51:05,120 --> 00:51:07,520
SARS-COV-2 INFECTION, AND ITS

1251
00:51:07,520 --> 00:51:09,600
POTENTIAL ROLE IN POST-ACUTE

1252
00:51:09,600 --> 00:51:09,880
SYNDROME.

1253
00:51:09,880 --> 00:51:10,920
NCCIH WAS CLOSELY INVOLVED IN

1254
00:51:10,920 --> 00:51:16,280
DESIGN OF THE RECOVER INITIATIVE

1255
00:51:16,280 --> 00:51:19,760
AND THERE WILL BE MANY

1256
00:51:19,760 --> 00:51:21,720
OPPORTUNITIES TO TEST PHYSICAL,

1257
00:51:21,720 --> 00:51:24,080
PSYCHOLOGICAL INTERVENTIONS AS A

1258
00:51:24,080 --> 00:51:24,960
FOLLOW-UP TO THE COHORTS.

1259
00:51:24,960 --> 00:51:30,320
I WANT TO TAKE A LOOK AT SOME

1260
00:51:30,320 --> 00:51:31,560
RECENT NCCIH RESEARCH

1261
00:51:31,560 --> 00:51:31,880
HIGHLIGHTS.

1262
00:51:31,880 --> 00:51:38,680
FIRST OF ALL, THIS IS AN 

1263
00:51:38,680 --> 00:51:40,520
INTERESTING STUDY, A COMPONENT

1264
00:51:40,520 --> 00:51:45,440
OF THE TULSI, HOLY BASIL,

1265
00:51:45,440 --> 00:51:47,840
TREATING COVID-19.

1266
00:51:47,840 --> 00:51:49,040
THIS COMPOUND INHIBITED

1267
00:51:49,040 --> 00:51:52,680
INTERACTION BETWEEN SPIKE 

1268
00:51:52,680 --> 00:52:02,560
PROTEIN AND ACE-2 RECEPTORS, AND

1269
00:52:02,560 --> 00:52:04,200
ALSO INHIBITED BINDING OF SPIKE

1270
00:52:04,200 --> 00:52:21,360
PROTEIN TO THE COVID VIRUS, 

1271
00:52:21,360 --> 00:52:22,400
SARS-COV-2 VIRUS, ENHANCING

1272
00:52:22,400 --> 00:52:23,800
BEHAVIOR IN MICE.

1273
00:52:23,800 --> 00:52:25,120
STILL TOO EARLY TO KNOW, THIS

1274
00:52:25,120 --> 00:52:31,840
HAS NOT BEEN TESTED IN HUMANS, 

1275
00:52:31,840 --> 00:52:37,120
BUT VERY INTERESTING INDEED.

1276
00:52:37,120 --> 00:52:41,320
AND USING GREEN LIGHT IN A MOUSE

1277
00:52:41,320 --> 00:52:43,200
MODEL OF PAIN.

1278
00:52:43,200 --> 00:52:45,720
THIS IS ALSO VERY INTERESTING

1279
00:52:45,720 --> 00:52:49,120
BECAUSE THIS GREEN LIGHT OF NOT 

1280
00:52:49,120 --> 00:52:54,080
ONLY REDUCED PAIN BUT ALSO BETA

1281
00:52:54,080 --> 00:52:57,680
ENDORPHINS, AND HERE YOU CAN SEE

1282
00:52:57,680 --> 00:53:00,400
THERE'S THIS MARKED REVERSAL OF

1283
00:53:00,400 --> 00:53:02,840
PAIN SENSITIVITY, HIV-RELATED

1284
00:53:02,840 --> 00:53:05,640
MODEL OF NEUROPATHIC PAIN.

1285
00:53:05,640 --> 00:53:07,160
ANOTHER INTERESTING STUDY OF

1286
00:53:07,160 --> 00:53:09,120
BACK PAIN, ASSOCIATION OF BACK

1287
00:53:09,120 --> 00:53:15,360
PAIN WITH MORTALITY.

1288
00:53:15,360 --> 00:53:18,200
WE KNOW, IT WAS NOT CLEAR, WE

1289
00:53:18,200 --> 00:53:20,840
KNOW IT'S ASSOCIATED WITH GREAT

1290
00:53:20,840 --> 00:53:22,360
MORBIDITY BUT WASN'T CLEAR

1291
00:53:22,360 --> 00:53:24,000
WHETHER DISABILITY IS GENERALLY

1292
00:53:24,000 --> 00:53:25,640
ASSOCIATED WITH MORTALITY.

1293
00:53:25,640 --> 00:53:29,040
THIS PARTICULAR STUDY LOOKED AT

1294
00:53:29,040 --> 00:53:30,120
81,000 PARTICIPANTS FOLLOWED FOR

1295
00:53:30,120 --> 00:53:32,200
5 TO 23 YEARS, AND PRESENCE OF

1296
00:53:32,200 --> 00:53:38,520
ANY BACK PAIN COMPARED TO NONE, 

1297
00:53:38,520 --> 00:53:40,480
WAS NOT ASSOCIATED WITH INCREASE

1298
00:53:40,480 --> 00:53:41,600
IN MORTALITY, WAS ASSOCIATED

1299
00:53:41,600 --> 00:53:43,040
WITH INCREASE IN MORTALITY IN

1300
00:53:43,040 --> 00:53:44,440
WOMEN AND ADULTS WITH MORE

1301
00:53:44,440 --> 00:53:45,720
SEVERE BACK PAIN.

1302
00:53:45,720 --> 00:53:48,360
AND FINALLY I WANT TO POINT OUT

1303
00:53:48,360 --> 00:53:50,760
THIS STUDY TALKING ABOUT THE

1304
00:53:50,760 --> 00:53:54,160
HEALTH CARE SYSTEMS RESEARCH

1305
00:53:54,160 --> 00:53:55,480
COLLABORATORY, PRAGMATIC TRIALS

1306
00:53:55,480 --> 00:53:59,400
COLLABORATORY, AND THIS IS A

1307
00:53:59,400 --> 00:54:01,040
STUDY THAT WAS RECENTLY

1308
00:54:01,040 --> 00:54:02,920
PUBLISHED, THAT REALLY

1309
00:54:02,920 --> 00:54:04,400
HIGHLIGHTS SOME OF THE

1310
00:54:04,400 --> 00:54:05,480
IMPORTANT -- WHAT WE'VE LEARNED

1311
00:54:05,480 --> 00:54:06,520
ABOUT USING ELECTRONIC HEALTH

1312
00:54:06,520 --> 00:54:07,800
RECORD IN PRAGMATIC TRIALS.

1313
00:54:07,800 --> 00:54:09,440
AND SO I ENCOURAGE YOU TO CHECK

1314
00:54:09,440 --> 00:54:10,200
THIS OUT.

1315
00:54:10,200 --> 00:54:14,840
IT'S A VERY NICE SUMMARY OF

1316
00:54:14,840 --> 00:54:17,720
LESSONS LEARNED IN THE PRAGMATIC

1317
00:54:17,720 --> 00:54:18,440
TRIALS COLLABORATORY.

1318
00:54:18,440 --> 00:54:21,360
I WANT TO RUN THROUGH SOME

1319
00:54:21,360 --> 00:54:24,200
FUNDING OPPORTUNITIES, POINTING

1320
00:54:24,200 --> 00:54:27,680
OUT TO YOU THAT WE HAVE

1321
00:54:27,680 --> 00:54:31,320
RECEIVED, FOR EXAMPLE, THIS

1322
00:54:31,320 --> 00:54:33,600
PARTICULAR ONE IS AN RFA OF THE

1323
00:54:33,600 --> 00:54:34,920
HEALTH CARE SYSTEMS RESEARCH

1324
00:54:34,920 --> 00:54:36,640
COLLABORATORY THAT WE ALREADY

1325
00:54:36,640 --> 00:54:38,080
HAD ONE RECEIPT DATE IN THE

1326
00:54:38,080 --> 00:54:40,280
FALL, AND I WANT TO POINT OUT

1327
00:54:40,280 --> 00:54:42,240
THERE'S ANOTHER RECEIPT DATE IN

1328
00:54:42,240 --> 00:54:43,240
JUNE 18.

1329
00:54:43,240 --> 00:54:46,000
AND THIS IS FOR PRAGMATIC AND

1330
00:54:46,000 --> 00:54:47,400
IMPLEMENT TRIALS OF EMBEDDED

1331
00:54:47,400 --> 00:54:48,920
INTERVENTIONS, SO WANT TO ALERT

1332
00:54:48,920 --> 00:54:52,880
YOU HERE OF THAT ADDITIONAL

1333
00:54:52,880 --> 00:54:53,920
RECEIPT DATE.

1334
00:54:53,920 --> 00:54:59,640
THERE'S ANOTHER OPPORTUNITY FOR

1335
00:54:59,640 --> 00:55:02,920
FUNDING FROM THE NIH, PAIN

1336
00:55:02,920 --> 00:55:04,720
MANAGEMENT COLLABORATORY FOR

1337
00:55:04,720 --> 00:55:08,240
PRAGMATIC AND IMPLEMENTATION

1338
00:55:08,240 --> 00:55:12,720
SCIENCE DEMONSTRATION PROJECTS,

1339
00:55:12,720 --> 00:55:13,320
ON MARCH 16.

1340
00:55:13,320 --> 00:55:17,800
THIS IS ALSO A NOTICE OF SPECIAL

1341
00:55:17,800 --> 00:55:20,000
INTEREST FOR SUPPLEMENTS ON HIGH

1342
00:55:20,000 --> 00:55:22,520
PRIORITY TOPIC AREAS FOR GRANTS

1343
00:55:22,520 --> 00:55:24,800
INCLUDING NATURAL PRODUCTS, MIND

1344
00:55:24,800 --> 00:55:26,320
AND BODY APPROACHES, AND

1345
00:55:26,320 --> 00:55:27,120
FUNDAMENTAL SCIENCE AND

1346
00:55:27,120 --> 00:55:29,760
TECHNOLOGY, AS WELL AS CLINICAL

1347
00:55:29,760 --> 00:55:30,040
RESEARCH.

1348
00:55:30,040 --> 00:55:34,960
AND SO THIS IS ALSO -- THE DUE

1349
00:55:34,960 --> 00:55:37,520
DATE IS JUNE 2.

1350
00:55:37,520 --> 00:55:41,520
THERE'S ALSO AN OPPORTUNITY HERE

1351
00:55:41,520 --> 00:55:43,280
FOR EXISTING NCCIH-FUNDED

1352
00:55:43,280 --> 00:55:47,920
PERSONS TO NATIONAL RESEARCH

1353
00:55:47,920 --> 00:55:49,720
SERVICE AWARDS, T32 PROGRAMS TO

1354
00:55:49,720 --> 00:55:58,640
APPLY FOR SUPPLEMENTS TO SUPPORT

1355
00:55:58,640 --> 00:56:00,440
CANDIDATES FROM DIVERSE

1356
00:56:00,440 --> 00:56:01,600
BACKGROUNDS INCLUDING

1357
00:56:01,600 --> 00:56:03,280
UNDERREPRESENTED IN THE

1358
00:56:03,280 --> 00:56:05,120
BIOMEDICAL, CLINICAL,

1359
00:56:05,120 --> 00:56:06,560
BEHAVIORAL, SOCIAL SCIENCES.

1360
00:56:06,560 --> 00:56:10,280
AND THIS IS ANOTHER OPPORTUNITY

1361
00:56:10,280 --> 00:56:12,240
FOR EXISTING NCCIH-FUNDED

1362
00:56:12,240 --> 00:56:14,600
RESEARCH SERVICE AWARDS,

1363
00:56:14,600 --> 00:56:16,080
INSTITUTIONAL RESEARCH TRAINING

1364
00:56:16,080 --> 00:56:18,040
GRANTS, T32 PROGRAMS, TO APPLY

1365
00:56:18,040 --> 00:56:20,520
FOR OTHER TIMES OF SUPPLEMENTS

1366
00:56:20,520 --> 00:56:22,080
TO SUPPORT ADDITIONAL TRAINING

1367
00:56:22,080 --> 00:56:29,080
SLOT TO SUPPORT PRE-DOCTORAL AND

1368
00:56:29,080 --> 00:56:34,720
POSTDOCTORAL CANDIDATES WITH 

1369
00:56:34,720 --> 00:56:43,080
INTEGRATIVE HEALTH DEGREES.

1370
00:56:43,080 --> 00:56:44,800
ALSO, THIS NOTICE OF SPECIAL

1371
00:56:44,800 --> 00:56:47,120
INTEREST TO HIGHLIGHT INTEREST

1372
00:56:47,120 --> 00:56:48,840
IN RESEARCH TO STRENGTHEN

1373
00:56:48,840 --> 00:56:50,040
UNDERSTANDING AND RESPONSE TO

1374
00:56:50,040 --> 00:56:51,680
COVID-19 PANDEMIC.

1375
00:56:51,680 --> 00:56:55,040
AND HELP US PREPARE FOR FUTURE

1376
00:56:55,040 --> 00:56:55,720
PUBLIC HEALTH EMERGENCIES.

1377
00:56:55,720 --> 00:57:00,120
SO, THE PURPOSE OF THIS NOTICE 

1378
00:57:00,120 --> 00:57:04,360
IS TO EMPHASIZE THE ROLE OF

1379
00:57:04,360 --> 00:57:07,960
INTERVENTION ON INDIVIDUAL 

1380
00:57:07,960 --> 00:57:08,800
HEALTH AND COMMUNITY ENGAGED

1381
00:57:08,800 --> 00:57:11,280
INTERVENTION IN HEALTH CARE

1382
00:57:11,280 --> 00:57:16,360
SETTINGS TO ADDRESS ACCESS,

1383
00:57:16,360 --> 00:57:19,520
DELIVERY, ENGAGEMENT,

1384
00:57:19,520 --> 00:57:20,280
SCALABILITY, SERVICES UTILIZED

1385
00:57:20,280 --> 00:57:25,000
DURING AND FOLLOWING THE

1386
00:57:25,000 --> 00:57:26,200
PANDEMIC.

1387
00:57:26,200 --> 00:57:27,440
A FEW WORDS ABOUT HEAL

1388
00:57:27,440 --> 00:57:28,360
INITIATIVE-RELATED ITEMS.

1389
00:57:28,360 --> 00:57:30,360
WE HAD A FANTASTIC TURNOUT FOR

1390
00:57:30,360 --> 00:57:33,960
OUR MEETING IN JULY, APPROACHES

1391
00:57:33,960 --> 00:57:34,720
TO EFFECTIVE THERAPEUTIC

1392
00:57:34,720 --> 00:57:36,360
MANAGEMENT OF PAIN FOR PEOPLE

1393
00:57:36,360 --> 00:57:41,560
WITH SICKLE CELL DISEASE, AND

1394
00:57:41,560 --> 00:57:43,440
POSTED ON THE WEBSITE.

1395
00:57:43,440 --> 00:57:46,760
WE HAD A HEAL INITIATIVE RFA,

1396
00:57:46,760 --> 00:57:47,320
NOW CLOSED.

1397
00:57:47,320 --> 00:57:52,720
AND APPLICATIONS ARE CURRENTLY

1398
00:57:52,720 --> 00:57:53,320
UNDER REVIEW.

1399
00:57:53,320 --> 00:57:56,720
ALSO, COUNSEL SILL APPROVED THIS

1400
00:57:56,720 --> 00:58:03,480
CONCEPT FOR THE MYOFASCIAL PAIN

1401
00:58:03,480 --> 00:58:05,440
HEAL INITIATIVE, DEVELOPING

1402
00:58:05,440 --> 00:58:06,520
BIOMARKERS, IMPORTANTLY THIS RFA

1403
00:58:06,520 --> 00:58:08,640
IS STILL OPEN.

1404
00:58:08,640 --> 00:58:11,480
DEADLINE IS FEBRUARY 12.

1405
00:58:11,480 --> 00:58:13,320
WE HAD A SEMINAR ON DECEMBER 2

1406
00:58:13,320 --> 00:58:16,520
IF YOU'RE STILL INTERESTED IN

1407
00:58:16,520 --> 00:58:17,720
LOOKING AT THIS, VIDEOCAST IS

1408
00:58:17,720 --> 00:58:19,480
AVAILABLE ONLINE.

1409
00:58:19,480 --> 00:58:21,520
WE ALSO HAD A RESEARCHING

1410
00:58:21,520 --> 00:58:22,880
NETWORKING SESSION ON JANUARY 6

1411
00:58:22,880 --> 00:58:25,160
TO PAIR UP PEOPLE WHO ARE

1412
00:58:25,160 --> 00:58:27,000
INTERESTED IN DOING RESEARCH

1413
00:58:27,000 --> 00:58:29,720
FROM THE CLINICAL SIDE,

1414
00:58:29,720 --> 00:58:32,560
CLINICIANS WITH EXPERTISE IN

1415
00:58:32,560 --> 00:58:34,680
MYOFASCIAL PAIN SYNDROME, WITH

1416
00:58:34,680 --> 00:58:36,200
TOOL DEVELOPERS FOR ENGINEERING,

1417
00:58:36,200 --> 00:58:38,320
PEOPLE WHO HAVE EXPERTISE IN

1418
00:58:38,320 --> 00:58:39,600
DEVELOPING IMAGING OR OTHER

1419
00:58:39,600 --> 00:58:41,400
TYPES OF BIOMARKERS.

1420
00:58:41,400 --> 00:58:43,680
THERE'S STILL SOME TIME.

1421
00:58:43,680 --> 00:58:46,720
BUT IT'S COMING UP SOON.

1422
00:58:46,720 --> 00:58:48,240
FINALLY, I WANT TO MENTION THIS

1423
00:58:48,240 --> 00:58:49,320
NEW INITIATIVE WHICH WE'RE GOING

1424
00:58:49,320 --> 00:58:52,520
TO TALK ABOUT AGAIN THIS

1425
00:58:52,520 --> 00:58:55,120
AFTERNOON, DR. CRISWELL FROM

1426
00:58:55,120 --> 00:58:56,120
NATIONAL INSTITUTES OF ARTHRITIS

1427
00:58:56,120 --> 00:59:00,360
IS GOING TO TALK ABOUT THIS HEAL

1428
00:59:00,360 --> 00:59:02,240
INITIATIVE OF JOINT PAIN,

1429
00:59:02,240 --> 00:59:03,920
RESTORING JOINT HEALTH AND

1430
00:59:03,920 --> 00:59:07,160
FUNCTION TO REDUCE PAIN CALLED

1431
00:59:07,160 --> 00:59:08,480
RE-JOIN.

1432
00:59:08,480 --> 00:59:09,920
AGAIN, THE DEADLINE IS APRIL 12.

1433
00:59:09,920 --> 00:59:12,720
AND ALSO THERE'S GOING TO BE A

1434
00:59:12,720 --> 00:59:15,320
TECHNICAL ASSISTANCE WEBINAR FOR

1435
00:59:15,320 --> 00:59:16,920
THIS ON WEDNESDAY, FEBRUARY 9.

1436
00:59:16,920 --> 00:59:19,440
SO THIS IS POSTED ON THE NIAMS

1437
00:59:19,440 --> 00:59:19,680
WEBSITE.

1438
00:59:19,680 --> 00:59:23,320
AGAIN, WE'LL BE HEARING MORE

1439
00:59:23,320 --> 00:59:24,760
ABOUT THIS THIS AFTERNOON.

1440
00:59:24,760 --> 00:59:28,400
PAST ACTIVITIES AND EVENTS, WE 

1441
00:59:28,400 --> 00:59:31,240
HAD A FANTASTIC WORKSHOP FOR

1442
00:59:31,240 --> 00:59:33,320
APPROACH TO WHOLE PERSON HEALTH.

1443
00:59:33,320 --> 00:59:36,160
AND THIS WORKSHOP ALSO THE VIDEO

1444
00:59:36,160 --> 00:59:38,640
IS ON THE WEBSITE, WE'LL HAVE A

1445
00:59:38,640 --> 00:59:39,280
SUMMARY FAIRLY SOON.

1446
00:59:39,280 --> 00:59:43,120
THIS LOOKED AT HOW TO STUDY

1447
00:59:43,120 --> 00:59:44,840
INTERCONNECTED SYSTEMS, IMPACT

1448
00:59:44,840 --> 00:59:46,520
OF SINGLE COMPONENT INTERVENTION

1449
00:59:46,520 --> 00:59:48,400
ON MULTIPLE SYSTEMS, IMPACT OF

1450
00:59:48,400 --> 00:59:50,360
MULTIPLE COMPONENT ON BOTH

1451
00:59:50,360 --> 00:59:55,800
SINGLE OUTCOMES AND MULTI-ORGAN

1452
00:59:55,800 --> 00:59:56,120
OUTCOMES.

1453
00:59:56,120 --> 00:59:58,000
FASCINATING ACTION ITEM, WE'RE

1454
00:59:58,000 --> 01:00:00,960
GOING TO FOLLOW UP WITH THIS

1455
01:00:00,960 --> 01:00:03,280
WITH MANY DIFFERENT TYPES OF

1456
01:00:03,280 --> 01:00:04,920
FUNDING INITIATIVES.

1457
01:00:04,920 --> 01:00:07,920
WE HAD A WONDERFUL INTEGRATIVE

1458
01:00:07,920 --> 01:00:11,760
MEDICINE RESEARCH LECTURE, DR.

1459
01:00:11,760 --> 01:00:14,960
YOUNG PRESENTED ON READING

1460
01:00:14,960 --> 01:00:20,520
BETWEEN THE TWEETS, VIDEOCAST IS

1461
01:00:20,520 --> 01:00:20,760
AVAILABLE.

1462
01:00:20,760 --> 01:00:22,520
THE STRESS LECTURE WAS WONDERFUL

1463
01:00:22,520 --> 01:00:23,200
THIS YEAR.

1464
01:00:23,200 --> 01:00:27,200
MINDFULNESS AS A SUPPORT FOR

1465
01:00:27,200 --> 01:00:29,080
HEALING CONVERSATIONS TOWARD

1466
01:00:29,080 --> 01:00:32,480
SOCIAL JUSTICE INEQUITY, WANDA

1467
01:00:32,480 --> 01:00:34,120
MAGEE GAVE A FANTASTIC LECTURE,

1468
01:00:34,120 --> 01:00:35,960
WATCH IF YOU'RE INTERESTED ON

1469
01:00:35,960 --> 01:00:40,000
OUR VIDEOCAST ON THE WEBSITE.

1470
01:00:40,000 --> 01:00:41,720
COMING EVENTS, SAVE THE DATE,

1471
01:00:41,720 --> 01:00:46,160
WE'LL HAVE A WORKSHOP ON

1472
01:00:46,160 --> 01:00:47,440
PRECISION PROBIOTICS, APRIL

1473
01:00:47,440 --> 01:00:47,760
26-27.

1474
01:00:47,760 --> 01:00:49,720
GOAL IS TO IDENTIFY KNOWLEDGE

1475
01:00:49,720 --> 01:00:51,920
GAPS FROM CURRENT METHODOLOGY

1476
01:00:51,920 --> 01:00:55,640
AND CHALLENGE IN PROBIOTIC

1477
01:00:55,640 --> 01:00:58,480
RESEARCH, FUTURE DIRECTIONS OF

1478
01:00:58,480 --> 01:00:58,800
THERAPIES.

1479
01:00:58,800 --> 01:01:02,600
AND SO AGAIN THE LINK IS ON THE

1480
01:01:02,600 --> 01:01:03,560
WEBSITE.

1481
01:01:03,560 --> 01:01:05,960
THE ANNUAL PAIN CONSORTIUM

1482
01:01:05,960 --> 01:01:07,200
SYMPOSIUM, THIS YEAR JUNE 1 AND

1483
01:01:07,200 --> 01:01:08,840
2, FOCUSING ON PAIN MANAGEMENT

1484
01:01:08,840 --> 01:01:11,560
FOR THE LENS OF WHOLE PERSON

1485
01:01:11,560 --> 01:01:11,800
HEALTH.

1486
01:01:11,800 --> 01:01:14,640
THIS SHOULD BE VERY INTERESTING.

1487
01:01:14,640 --> 01:01:18,480
SAVE THE DATE.

1488
01:01:18,480 --> 01:01:19,560
ALSO, INTERNATIONAL CONSORTIUM

1489
01:01:19,560 --> 01:01:23,160
FOR CONGRESS, EXCUSE ME,

1490
01:01:23,160 --> 01:01:25,000
INTEGRATIVE MEDICINE AND HEALTH

1491
01:01:25,000 --> 01:01:31,040
IN PHOENIX IN MAY, ORGANIZED BY

1492
01:01:31,040 --> 01:01:34,920
NCCIH, CAREER DEVELOPMENT, 

1493
01:01:34,920 --> 01:01:37,520
TRANSLATING YOUR RESEARCH,

1494
01:01:37,520 --> 01:01:38,840
HARNESSING MUSIC INTERVENTIONS,

1495
01:01:38,840 --> 01:01:39,480
MINDFULNESS-BASED TREATMENT FOR

1496
01:01:39,480 --> 01:01:42,440
CHRONIC PAIN OR OPIOID MISUSE,

1497
01:01:42,440 --> 01:01:48,000
SCIENCE AND PRACTICE OF

1498
01:01:48,000 --> 01:01:49,720
CANNABINOID-BASED THERAPIES,

1499
01:01:49,720 --> 01:01:54,240
PAIN MANAGEMENT COLLABORATORY, 

1500
01:01:54,240 --> 01:01:59,720
PRAGMATIC TRIALS, GUT 

1501
01:01:59,720 --> 01:02:01,360
MICROBIOME, ALTERNATIVES TO

1502
01:02:01,360 --> 01:02:02,000
OPIOIDS, GLYMPHATIC AND

1503
01:02:02,000 --> 01:02:04,280
LYMPHATIC CLEARANCE AND SLEEP.

1504
01:02:04,280 --> 01:02:09,000
CHECK OUT THIS FANTASTIC LINEUP

1505
01:02:09,000 --> 01:02:10,400
OF SYMPOSIA AND HOPEFULLY WE'LL

1506
01:02:10,400 --> 01:02:14,080
SEE YOU IN PERSON, IF NOT IN

1507
01:02:14,080 --> 01:02:21,560
JUNE, FOR THE MEETING.

1508
01:02:21,560 --> 01:02:26,080
ICIMH, I'LL HAVE A SYMPOSIUM 

1509
01:02:26,080 --> 01:02:30,520
WITH DR. SUZANNE SIMARD,

1510
01:02:30,520 --> 01:02:32,120
RESEARCHER ON FORESTRY, IMPACT

1511
01:02:32,120 --> 01:02:35,280
ON HUMANS AND FORESTS.

1512
01:02:35,280 --> 01:02:39,880
AND DR. SIMARD IS A PIONEER IN

1513
01:02:39,880 --> 01:02:44,360
PROMOTING ECOLOGICAL AND WHOLE

1514
01:02:44,360 --> 01:02:45,280
FOREST MANAGEMENT OF NATURE, AND

1515
01:02:45,280 --> 01:02:48,160
SO WE'RE GOING TO LOOK FORWARD

1516
01:02:48,160 --> 01:02:49,480
TO A BIG CONVERSATION BETWEEN

1517
01:02:49,480 --> 01:02:52,000
THE TWO OF US, WE FEEL THERE'S A

1518
01:02:52,000 --> 01:02:54,520
LOT OF PARALLEL WITH WHAT SHE'S

1519
01:02:54,520 --> 01:02:55,840
ADVOCATING AND WHAT WHAT WE'RE

1520
01:02:55,840 --> 01:02:58,040
WORKING ON, THE SUBJECT OF WHOLE

1521
01:02:58,040 --> 01:03:00,880
PERSON HEALTH.

1522
01:03:00,880 --> 01:03:03,680
AND FINALLY, OUR NEXT NCCIM

1523
01:03:03,680 --> 01:03:06,280
MEETING, MEETING WITH THE

1524
01:03:06,280 --> 01:03:07,920
COUNCIL, ADVISORY COUNCIL FOR

1525
01:03:07,920 --> 01:03:09,000
THE COMPLEMENTARY AND

1526
01:03:09,000 --> 01:03:12,200
INTEGRATIVE HEALTH, IS ON MAY

1527
01:03:12,200 --> 01:03:12,520
13.

1528
01:03:12,520 --> 01:03:16,520
AND PLEASE SAVE THE DATE FOR

1529
01:03:16,520 --> 01:03:16,720
THAT.

1530
01:03:16,720 --> 01:03:21,680
SO I'M NOW OVER TIME BUT I'M

1531
01:03:21,680 --> 01:03:23,280
GOING TO PAUSE.

1532
01:03:23,280 --> 01:03:26,080
I'LL STOP MY SHARE AND SEE IF WE

1533
01:03:26,080 --> 01:03:29,400
WANT TO GIVE DR. EDWARDS A

1534
01:03:29,400 --> 01:03:31,040
CHANCE TO PRESENT HER -- DO WE

1535
01:03:31,040 --> 01:03:32,480
HAVE TIME FOR QUESTIONS OR

1536
01:03:32,480 --> 01:03:37,760
SHOULD WE MOVE TO EMMELINE?

1537
01:03:37,760 --> 01:03:38,640
>>  GOOD QUESTION.

1538
01:03:38,640 --> 01:03:40,960
I DID WANT TO SEE IF THERE ARE

1539
01:03:40,960 --> 01:03:42,560
QUESTIONS FROM COUNCIL RELATED

1540
01:03:42,560 --> 01:03:43,840
TO DR. LANGEVIN'S PRESENTATION.

1541
01:03:43,840 --> 01:03:47,480
WE'RE ALSO RUNNING UP AGAINST

1542
01:03:47,480 --> 01:03:51,120
THE LUNCH HOUR, LUNCH HALF HOUR.

1543
01:03:51,120 --> 01:03:52,720
>> I APOLOGIZE, I WENT OVER.

1544
01:03:52,720 --> 01:03:53,920
>> WE COULD MOVE EMMELINE'S TALK

1545
01:03:53,920 --> 01:03:55,720
TO THIS AFTERNOON.

1546
01:03:55,720 --> 01:03:57,440
>> I'M FINE WITH THAT.

1547
01:03:57,440 --> 01:03:58,320
>> THAT WOULD GIVE COUNCIL

1548
01:03:58,320 --> 01:04:01,120
MEMBERS, IF THEY HAVE ANY

1549
01:04:01,120 --> 01:04:02,000
QUESTIONS, BECAUSE WE'RE

1550
01:04:02,000 --> 01:04:06,720
SCHEDULED TO BREAK FOR LUNCH 

1551
01:04:06,720 --> 01:04:09,680
LITERALLY SORT OF NOW.

1552
01:04:09,680 --> 01:04:12,040
COUNCIL? 

1553
01:04:12,040 --> 01:04:16,840
WHAT SAY YE?

1554
01:04:16,840 --> 01:04:17,160
DR. HANEY?

1555
01:04:17,160 --> 01:04:19,360
>>  DO WE HAVE SENSE OF WHEN THE

1556
01:04:19,360 --> 01:04:21,440
BUDGET MIGHT GET APPROVED?

1557
01:04:21,440 --> 01:04:24,120
IS THERE ANY GUESS AT ALL?

1558
01:04:24,120 --> 01:04:25,480
>>  NO GUESS.

1559
01:04:25,480 --> 01:04:28,800
WE'RE HOLDING OUR BREATH AND

1560
01:04:28,800 --> 01:04:30,360
WAITING. 

1561
01:04:30,360 --> 01:04:30,760
>> THANKS.

1562
01:04:30,760 --> 01:04:33,680
 

1563
01:04:33,680 --> 01:04:36,080
>> OTHER QUESTIONS OR COMMENTS

1564
01:04:36,080 --> 01:04:51,040
BY COUNCIL? 

1565
01:04:51,040 --> 01:04:51,320
YEAH, WOLF?

1566
01:04:51,320 --> 01:04:53,320
>>  IF THIS COMES THROUGH, THE

1567
01:04:53,320 --> 01:04:55,640
BUDGET INCREASE, IS THERE A

1568
01:04:55,640 --> 01:04:58,320
CHANCE THAT A 10% CUT IN

1569
01:04:58,320 --> 01:05:00,600
RESEARCH BUDGETS FOR R34 FOR

1570
01:05:00,600 --> 01:05:03,920
YEAR TWO CAN BE REVERSED?

1571
01:05:03,920 --> 01:05:05,720
>> ALL OF THIS WILL HAVE BEEN TO

1572
01:05:05,720 --> 01:05:07,600
BE TAKEN INTO CONSIDERATION,

1573
01:05:07,600 --> 01:05:09,120
ONCE WE KNOW THE AMOUNT OF MONEY

1574
01:05:09,120 --> 01:05:10,120
THAT WE HAVE.

1575
01:05:10,120 --> 01:05:10,400
>> OKAY.

1576
01:05:10,400 --> 01:05:11,800
>> WHEN WE'RE IN A CONTINUING

1577
01:05:11,800 --> 01:05:16,360
RESOLUTION, AS WE ARE RIGHT NOW,

1578
01:05:16,360 --> 01:05:17,520
THERE ARE CERTAIN BUDGET CAPS

1579
01:05:17,520 --> 01:05:19,360
WE'RE REQUIRED TO DO, JUST

1580
01:05:19,360 --> 01:05:19,920
BECAUSE WE'RE CONTINUING

1581
01:05:19,920 --> 01:05:21,000
RESOLUTION, AND THEN WE HAVE TO

1582
01:05:21,000 --> 01:05:24,120
SEE ONCE WE GET OUR ACTUAL

1583
01:05:24,120 --> 01:05:25,320
BUDGET, WE CAN ASSESS WHAT WE

1584
01:05:25,320 --> 01:05:29,320
CAN DO AT THAT POINT.

1585
01:05:29,320 --> 01:05:29,600
>> YEAH.

1586
01:05:29,600 --> 01:05:30,440
>> THANK YOU.

1587
01:05:30,440 --> 01:05:32,920
>> TO BE EXPLICIT, WE HAVE

1588
01:05:32,920 --> 01:05:34,480
CONTINUING RESOLUTIONS, WE'RE

1589
01:05:34,480 --> 01:05:36,640
REQUIRED BY POLICY OR REGULATION

1590
01:05:36,640 --> 01:05:39,280
ACTUALLY TO NOT FUND THE

1591
01:05:39,280 --> 01:05:43,000
COMPETING AWARDS, BUT THE

1592
01:05:43,000 --> 01:05:45,320
NON-COMPETING AWARDS AT 100%, IT

1593
01:05:45,320 --> 01:05:48,320
USUALLY GETS CAPPED AT 90%.

1594
01:05:48,320 --> 01:05:50,720
AND IF AND WHEN WE GET A BUDGET,

1595
01:05:50,720 --> 01:05:52,520
DEPENDING UPON THE BUDGET THAT

1596
01:05:52,520 --> 01:05:56,320
WE ACTUALLY GET, WE CAN CONSIDER

1597
01:05:56,320 --> 01:05:58,640
RESTORING SOME OR ALL OF THAT

1598
01:05:58,640 --> 01:06:02,280
FUNDS THAT HAVE BEEN HELD BACK

1599
01:06:02,280 --> 01:06:04,280
FOR THAT YEAR.

1600
01:06:04,280 --> 01:06:05,400
WE DO THIS AUTOMATICALLY,

1601
01:06:05,400 --> 01:06:07,920
THERE'S NO NEED FOR ANY AWARDEE

1602
01:06:07,920 --> 01:06:09,400
TO CONTACT AND SAY COULD YOU

1603
01:06:09,400 --> 01:06:11,520
GIVE ME THE MONEY THAT WE DIDN'T

1604
01:06:11,520 --> 01:06:11,920
GET.

1605
01:06:11,920 --> 01:06:13,640
WE WILL DO THAT AUTOMATICALLY IF

1606
01:06:13,640 --> 01:06:15,640
WE HAVE THE MONEY AND ONCE WE

1607
01:06:15,640 --> 01:06:18,680
GET A BUDGET.

1608
01:06:18,680 --> 01:06:23,520
>> THANK YOU, THANK YOU.

1609
01:06:23,520 --> 01:06:24,320
>> DR. LABREKSKY?

1610
01:06:24,320 --> 01:06:26,400
>>  A QUESTION ABOUT LONG COVID

1611
01:06:26,400 --> 01:06:26,920
FUNDING.

1612
01:06:26,920 --> 01:06:30,440
STRUCTURE OF THE FUNDING

1613
01:06:30,440 --> 01:06:35,320
DECISIONS IS CUMBERSOME, NOT

1614
01:06:35,320 --> 01:06:36,880
CLEAR HOW INSTITUTES WOULD MAKE

1615
01:06:36,880 --> 01:06:38,920
THE DECISIONS ON FUNDING WHEN

1616
01:06:38,920 --> 01:06:43,760
NYU IS IN THE MIDDLE OF IT.

1617
01:06:43,760 --> 01:06:44,840
>> WELL, IT'S MY UNDERSTANDING

1618
01:06:44,840 --> 01:06:50,160
THAT THEY ARE WORKING TOGETHER

1619
01:06:50,160 --> 01:06:51,080
WITH NIH.

1620
01:06:51,080 --> 01:06:53,840
THIS IS -- THEY ARE USING WHAT'S

1621
01:06:53,840 --> 01:06:55,680
CALLED THE OTHER TRANSACTION

1622
01:06:55,680 --> 01:06:57,520
AUTHORITY TO MAKE THIS

1623
01:06:57,520 --> 01:06:58,720
PARTICULAR FUNDING AWARD.

1624
01:06:58,720 --> 01:07:02,640
AND DECISIONS LIKE THIS ARE MADE

1625
01:07:02,640 --> 01:07:09,960
VERY MUCH IN TANDEM BETWEEN NIH

1626
01:07:09,960 --> 01:07:10,960
AND NYU, COLLABORATION GOING ON

1627
01:07:10,960 --> 01:07:15,360
BOTH WAYS THE WHOLE TIME. 

1628
01:07:15,360 --> 01:07:19,920
THIS IS A VERY, YOU KNOW, HIGH

1629
01:07:19,920 --> 01:07:20,920
INTENSITY PROJECT, AS YOU CAN

1630
01:07:20,920 --> 01:07:21,160
IMAGINE.

1631
01:07:21,160 --> 01:07:23,040
ALL OF THIS HAS TO HAPPEN IN

1632
01:07:23,040 --> 01:07:24,360
VERY, VERY SHORT AMOUNTS OF

1633
01:07:24,360 --> 01:07:24,560
TIME.

1634
01:07:24,560 --> 01:07:29,120
SO NIH HAS A LOT OF INPUT INTO

1635
01:07:29,120 --> 01:07:31,320
THIS. 

1636
01:07:31,320 --> 01:07:32,760
>> AND WHAT I FIND BAFFLING,

1637
01:07:32,760 --> 01:07:35,280
BECAUSE OF THIS OTHER FUNDING,

1638
01:07:35,280 --> 01:07:36,400
THE INSTITUTES ARE NOT WILLING

1639
01:07:36,400 --> 01:07:38,840
TO ENGAGE IN THE DISCUSSION OF

1640
01:07:38,840 --> 01:07:42,800
OTHER PROJECTS. 

1641
01:07:42,800 --> 01:07:44,960
YOU KNOW, BECAUSE IT'S

1642
01:07:44,960 --> 01:07:46,720
2.5 BILLION ALLOCATED, AND WHAP

1643
01:07:46,720 --> 01:07:48,480
IS THE NCCIH POSITION ON THAT

1644
01:07:48,480 --> 01:07:51,600
AND HOW DO I APPROACH IT?

1645
01:07:51,600 --> 01:07:52,680
>> WE DON'T HAVE ANY AUTHORITY

1646
01:07:52,680 --> 01:07:53,320
OVER THAT.

1647
01:07:53,320 --> 01:07:59,880
I MEAN, THIS IS ALL HANDLED BY

1648
01:07:59,880 --> 01:08:01,800
THE -- YOU KNOW, THE ENTIRE -- I

1649
01:08:01,800 --> 01:08:03,720
BELIEVE THIS IS THE OFFICE OF

1650
01:08:03,720 --> 01:08:04,800
THE DIRECTOR THAT'S ORGANIZING

1651
01:08:04,800 --> 01:08:10,920
THIS, BUT IT'S A 

1652
01:08:10,920 --> 01:08:13,120
MULTI-INSTITUTE, YOU KNOW,

1653
01:08:13,120 --> 01:08:13,480
CONSORTIUM.

1654
01:08:13,480 --> 01:08:15,880
WE CANNOT INFLUENTIAL HOW THAT

1655
01:08:15,880 --> 01:08:18,520
PARTICULAR -- I MEAN, I SIT ON

1656
01:08:18,520 --> 01:08:20,320
THE EXECUTIVE COMMITTEE FOR THE

1657
01:08:20,320 --> 01:08:22,960
PAST, AND I CAN TELL YOU THAT

1658
01:08:22,960 --> 01:08:27,680
THE WAY THAT THIS HAS BEEN

1659
01:08:27,680 --> 01:08:29,120
HAPPENING HAS BEEN -- HAS BEEN

1660
01:08:29,120 --> 01:08:30,840
DONE VERY, VERY CAREFULLY BUT

1661
01:08:30,840 --> 01:08:33,320
ALSO AT THE SAME TIME UNDER

1662
01:08:33,320 --> 01:08:34,360
TREMENDOUS TIME CONSTRAINTS.

1663
01:08:34,360 --> 01:08:36,000
YOU KNOW, PEOPLE DID THE BEST

1664
01:08:36,000 --> 01:08:41,560
THEY COULD UNDER THESE VERY

1665
01:08:41,560 --> 01:08:42,280
DIFFICULT CIRCUMSTANCES.

1666
01:08:42,280 --> 01:08:44,640
>> THE LAST QUESTION BEFORE THE

1667
01:08:44,640 --> 01:08:46,160
BREAK, WE'LL BREAK AFTER THIS

1668
01:08:46,160 --> 01:08:48,440
Q&A AND THEN WE CAN -- WE'LL

1669
01:08:48,440 --> 01:08:50,720
HAVE TIME LATER THIS AFTERNOON

1670
01:08:50,720 --> 01:08:53,560
WHEN WE COME BACK FROM LUNCH TO

1671
01:08:53,560 --> 01:08:55,560
HAVE MORE OPEN QUESTIONS AND

1672
01:08:55,560 --> 01:08:59,840
DISCUSSION WITH COUNCIL ON

1673
01:08:59,840 --> 01:09:01,160
VARIOUS THINGS.

1674
01:09:01,160 --> 01:09:04,080
>> THANKS FOR THAT WONDERFUL

1675
01:09:04,080 --> 01:09:07,240
OVER OVERVIEW OF THE EXCITING

1676
01:09:07,240 --> 01:09:08,880
PROGRAMS NCCIH IS INVOLVED IN OR

1677
01:09:08,880 --> 01:09:09,760
SPEARHEADING.

1678
01:09:09,760 --> 01:09:12,400
RELATED TO BUDGE IT, IT'S VERY

1679
01:09:12,400 --> 01:09:15,360
WONDERFUL TO SEE POTENTIAL FOR

1680
01:09:15,360 --> 01:09:16,400
BIG BUDGET INCREASE.

1681
01:09:16,400 --> 01:09:18,080
IT LOOKED LIKE THE DELTA BETWEEN

1682
01:09:18,080 --> 01:09:21,640
LAST YEAR AND THIS YEAR MIGHT BE

1683
01:09:21,640 --> 01:09:23,720
DUE TO -- I THINK YOU MENTIONED

1684
01:09:23,720 --> 01:09:25,880
SIGNIFICANT INCREASE IN FUNDING

1685
01:09:25,880 --> 01:09:28,000
FOR PAIN RESEARCH SPECIFICALLY.

1686
01:09:28,000 --> 01:09:30,320
IS THAT -- DID I INTERPRET THAT

1687
01:09:30,320 --> 01:09:32,080
CORRECTLY, IF TRUE FUNDS COME IN

1688
01:09:32,080 --> 01:09:34,560
EARMARKED FOR SPECIFIC PROGRAMS

1689
01:09:34,560 --> 01:09:34,920
LIKE THAT?

1690
01:09:34,920 --> 01:09:40,040
>>  WELL, IF THIS WERE TO

1691
01:09:40,040 --> 01:09:40,840
HAPPEN, THIS PARTICULAR AMOUNT

1692
01:09:40,840 --> 01:09:43,520
OF 26 MILLION I MENTIONED WOULD

1693
01:09:43,520 --> 01:09:46,480
BE FOR PAIN RESEARCH ONLY.

1694
01:09:46,480 --> 01:09:47,480
AND BUT NOT FOR SPECIFIC

1695
01:09:47,480 --> 01:09:47,720
PROJECTS.

1696
01:09:47,720 --> 01:09:50,720
IT WOULD HAVE TO BE FOR PAIN

1697
01:09:50,720 --> 01:09:51,520
RESEARCH.

1698
01:09:51,520 --> 01:09:52,280
AND SO BUT WE DON'T KNOW OF

1699
01:09:52,280 --> 01:09:54,360
COURSE IF THIS IS GOING TO 

1700
01:09:54,360 --> 01:09:58,480
HAPPEN OR NOT. 

1701
01:09:58,480 --> 01:09:59,920
>> THANK YOU.

1702
01:09:59,920 --> 01:10:00,480
>> OKAY.

1703
01:10:00,480 --> 01:10:01,920
>> AND THIS IS WHAT -- EMMELINE

1704
01:10:01,920 --> 01:10:03,640
IS GOING TO TELL US ABOUT SOME

1705
01:10:03,640 --> 01:10:06,040
OF THE -- OF WHAT WE'RE THINKING

1706
01:10:06,040 --> 01:10:08,120
ABOUT IN TERMS OF CREATING

1707
01:10:08,120 --> 01:10:09,760
OPPORTUNITIES THAT COULD TURN

1708
01:10:09,760 --> 01:10:10,520
AROUND REALLY, REALLY QUICKLY

1709
01:10:10,520 --> 01:10:13,920
BECAUSE ALL OF THIS WOULD HAVE

1710
01:10:13,920 --> 01:10:18,160
TO BE IN FY22.

1711
01:10:18,160 --> 01:10:19,280
AND THERE'S NOT A LOT OF TIME

1712
01:10:19,280 --> 01:10:19,520
LEFT.

1713
01:10:19,520 --> 01:10:24,320
WE HAVE TO BE PREPARED IN CASE

1714
01:10:24,320 --> 01:10:25,640
THIS HAPPENS?  WE'RE GOING TO

1715
01:10:25,640 --> 01:10:27,600
BREAK FOR LUNCH.

1716
01:10:27,600 --> 01:10:30,560
EMMELINE WILL DO A PRESENTATION

1717
01:10:30,560 --> 01:10:32,760
AFTER LUNCH, A SLOT AROUND 2:30

1718
01:10:32,760 --> 01:10:35,280
SHE WILL PRESENT THAT.

1719
01:10:35,280 --> 01:10:40,280
SO FOR COUNCIL MEMBERS, WE WILL

1720
01:10:40,280 --> 01:10:42,360
RETURN PROMPTLY AT 1:20 FOR THE

1721
01:10:42,360 --> 01:10:44,520
CONTINUATION OF THE OPEN

1722
01:10:44,520 --> 01:10:44,760
SESSION.

1723
01:10:44,760 --> 01:10:47,160
COUNCIL MEMBERS CAN TAKE LUNCH

1724
01:10:47,160 --> 01:10:49,320
ON THEIR OWN OR IF YOU WOULD

1725
01:10:49,320 --> 01:10:51,760
LIKE TO HAVE THE OPPORTUNITY TO

1726
01:10:51,760 --> 01:10:54,120
SORT OF EAT LUNCH WITH NCCIH

1727
01:10:54,120 --> 01:10:57,400
STAFF, IT WILL BE A LUNCH ROOM

1728
01:10:57,400 --> 01:10:59,720
BREAK OR LUNCHROOM THAT YOU'LL

1729
01:10:59,720 --> 01:11:02,680
BE INVITED TO JOIN VIA ZOOM, AND

1730
01:11:02,680 --> 01:11:05,760
YOU CAN JUST COME IN.

1731
01:11:05,760 --> 01:11:07,120
THERE WILL BE STAFF ALSO HAVING

1732
01:11:07,120 --> 01:11:08,880
LUNCH, YOU'RE WELCOME TO TALK

1733
01:11:08,880 --> 01:11:09,960
WITH STAFF AND COUNCIL MEMBERS

1734
01:11:09,960 --> 01:11:12,920
DURING YOUR LUNCH AND WE'LL ALL

1735
01:11:12,920 --> 01:11:14,920
RETURN FOR THE OPEN SESSION

1736
01:11:14,920 --> 01:11:17,720
WHICH WILL BE VIDEOCAST AT 1:20.

1737
01:11:17,720 --> 01:11:19,480
LUNCH BREAK IS NOT VIDEOCAST.

1738
01:11:19,480 --> 01:11:21,480
SO YOU'RE WELCOME TO JUST GO ON

1739
01:11:21,480 --> 01:11:24,200
YOUR OWN OR JOIN US OF SOME

1740
01:11:24,200 --> 01:11:27,360
STAFF IN THE LUNCH BREAK.

1741
01:11:27,360 --> 01:11:29,040
I'M GOING TO CONCLUDE THIS

1742
01:11:29,040 --> 01:11:31,320
PORTION OF THE OPEN SESSION.

1743
01:11:31,320 --> 01:11:32,440
WE'LL RETURN AT 1:20.

1744
01:11:32,440 --> 01:11:33,000
THANK YOU. 

1745
01:11:33,000 --> 01:11:34,520
>> WELCOME BACK.

1746
01:11:34,520 --> 01:11:38,440
WE'RE COMING BACK FROM LUNCH

1747
01:11:38,440 --> 01:11:40,960
BREAK, CONVENING THE OPEN

1748
01:11:40,960 --> 01:11:43,840
SESSION OF THE ADVISORY COUNCIL.

1749
01:11:43,840 --> 01:11:48,000
I HOPE EVERYONE GOT A LUNCH

1750
01:11:48,000 --> 01:11:49,080
BREAK, ET CETERA.

1751
01:11:49,080 --> 01:11:52,640
WE'RE NOW GOING INTO OUR NEXT

1752
01:11:52,640 --> 01:11:53,000
PRESENTATIONS.

1753
01:11:53,000 --> 01:11:59,000
DR. LANGEVIN, WOULD YOU LIKE TO

1754
01:11:59,000 --> 01:12:00,120
INTRODUCE DR. CRISWELL?

1755
01:12:00,120 --> 01:12:02,960
>>  WELL, IT'S MY GREAT PLEASURE

1756
01:12:02,960 --> 01:12:05,000
TO INTRODUCE DR. LINDSEY

1757
01:12:05,000 --> 01:12:07,280
CRISWELL, WHO IS DIRECTOR OF THE

1758
01:12:07,280 --> 01:12:09,680
NATIONAL INSTITUTES FOR

1759
01:12:09,680 --> 01:12:10,400
ARTHRITIS AND MUSCULOSKELETAL

1760
01:12:10,400 --> 01:12:12,000
AND SKIN DISEASE AT NIH.

1761
01:12:12,000 --> 01:12:18,760
IT'S REALLY A PRIVILEGE FOR US

1762
01:12:18,760 --> 01:12:24,560
TO HAVE DR. CRISWELL PRESENT.

1763
01:12:24,560 --> 01:12:25,240
WE'RE EXCITED.

1764
01:12:25,240 --> 01:12:27,720
SHE BECAME DIRECTOR OF NIAMS A

1765
01:12:27,720 --> 01:12:29,000
YEAR AGO.

1766
01:12:29,000 --> 01:12:36,040
SINCE THEN SHE'S BEEN A

1767
01:12:36,040 --> 01:12:38,120
WONDERFUL COLLEAGUE AND WE'RE

1768
01:12:38,120 --> 01:12:38,560
LOOKING FORWARD TO

1769
01:12:38,560 --> 01:12:40,800
COLLABORATIONS IN THE AREA OF

1770
01:12:40,800 --> 01:12:46,400
MUSCULOSKELETAL PAIN. 

1771
01:12:46,400 --> 01:12:47,960
DR. CRISWELL OVERSEES INTO THE

1772
01:12:47,960 --> 01:12:50,640
CAUSES, TREATMENT AND PREVENTION

1773
01:12:50,640 --> 01:12:52,360
OF ARTHRITIS AND MUSCULOSKELETAL

1774
01:12:52,360 --> 01:12:56,800
AND SKIN DISEASE, BOARD

1775
01:12:56,800 --> 01:12:57,440
CERTIFIED RHEUMATOLOGIST,

1776
01:12:57,440 --> 01:12:59,160
PREVIOUSLY VICE CHANCELLOR OF

1777
01:12:59,160 --> 01:13:00,560
RESEARCH UNIVERSITY OF

1778
01:13:00,560 --> 01:13:03,000
CALIFORNIA, SAN FRANCISCO,

1779
01:13:03,000 --> 01:13:12,280
PROFESSOR OF RHEUMATOLOGY,

1780
01:13:12,280 --> 01:13:13,920
DISTINGUISHED PROFESSORSHIP ALSO

1781
01:13:13,920 --> 01:13:14,800
IN RHEUMATOLOGY, OBTAINED

1782
01:13:14,800 --> 01:13:18,000
MASTER'S DEGREE IN PUBLIC HEALTH

1783
01:13:18,000 --> 01:13:21,040
UNIVERSITY OF CALIFORNIA

1784
01:13:21,040 --> 01:13:24,840
BERKELEY, M.D. UCSF, DSC IN

1785
01:13:24,840 --> 01:13:25,840
GENETIC EPIDEMIOLOGY FROM

1786
01:13:25,840 --> 01:13:27,960
NETHERLANDS INSTITUTES FOR

1787
01:13:27,960 --> 01:13:31,320
HEALTH SCIENCES IN ROTTERDAM.

1788
01:13:31,320 --> 01:13:34,040
SHE WAS PRINCIPAL INVESTIGATOR

1789
01:13:34,040 --> 01:13:35,120
OF MULTIPLE GRANTS, PUBLISHED

1790
01:13:35,120 --> 01:13:36,440
250 PEER-REVIEWED ARTICLES

1791
01:13:36,440 --> 01:13:38,320
FOCUSED ON GENETICS AND

1792
01:13:38,320 --> 01:13:40,400
EPIDEMIOLOGY OF HUMAN AUTOIMMUNE

1793
01:13:40,400 --> 01:13:42,720
DISEASE, ESPECIALLY RHEUMATOID

1794
01:13:42,720 --> 01:13:45,160
ARTHRITIS AND SYSTEMIC LUPUS.

1795
01:13:45,160 --> 01:13:46,600
WELCOME, DR. CRISWELL.

1796
01:13:46,600 --> 01:13:48,160
WE'RE EXCITED TO HEAR ABOUT WHAT

1797
01:13:48,160 --> 01:13:50,880
YOU CAN TELL US ABOUT DIRECTIONS

1798
01:13:50,880 --> 01:13:53,080
YOU'RE TAKING NIAMS AND AREAS

1799
01:13:53,080 --> 01:13:54,520
WHERE WE CAN COLLABORATE.

1800
01:13:54,520 --> 01:13:57,800
>> THANK YOU.

1801
01:13:57,800 --> 01:14:01,400
I APPRECIATE THE INVITATION, MY

1802
01:14:01,400 --> 01:14:02,800
FIRST OPPORTUNITY TO PRESENT TO

1803
01:14:02,800 --> 01:14:03,400
ANOTHER COUNCIL.

1804
01:14:03,400 --> 01:14:06,120
LET ME TRY TO SHARE MY SCREEN.

1805
01:14:06,120 --> 01:14:13,400
GIVE ME A MOMENT.

1806
01:14:13,400 --> 01:14:17,240
CAN YOU SEE THAT OKAY?

1807
01:14:17,240 --> 01:14:18,760
>>  YES.

1808
01:14:18,760 --> 01:14:19,440
>> GREAT.

1809
01:14:19,440 --> 01:14:19,640
OKAY.

1810
01:14:19,640 --> 01:14:22,440
SO, GOOD AFTERNOON.

1811
01:14:22,440 --> 01:14:24,560
IT'S A PLEASURE TO BE HERE, I

1812
01:14:24,560 --> 01:14:25,840
APPRECIATE THE OPPORTUNITY TO

1813
01:14:25,840 --> 01:14:29,480
SHARE HIGHLIGHTS OF THE PAIN

1814
01:14:29,480 --> 01:14:32,120
PORTFOLIO.

1815
01:14:32,120 --> 01:14:33,440
MY AGENDA IS PROVIDE HIGHLIGHTS

1816
01:14:33,440 --> 01:14:35,520
OF SHARED INTEREST IN PAIN

1817
01:14:35,520 --> 01:14:38,440
RESEARCH, I LOOK FORWARD TO A

1818
01:14:38,440 --> 01:14:40,160
ROBUST DISCUSSION WITH YOU.

1819
01:14:40,160 --> 01:14:42,960
I'M EXCITED TO OVERSEE THE WIDE

1820
01:14:42,960 --> 01:14:44,040
RANGING PORTFOLIO AND

1821
01:14:44,040 --> 01:14:47,000
OUTSTANDING WORK THAT THE

1822
01:14:47,000 --> 01:14:48,440
INSTITUTE SUPPORTS.

1823
01:14:48,440 --> 01:14:50,200
SINCE JOIN NIAMS I'VE BEEN

1824
01:14:50,200 --> 01:14:51,720
GETTING TO KNOW FELLOW DIRECTORS

1825
01:14:51,720 --> 01:14:53,160
AND EXPLORING WAYS WE CAN

1826
01:14:53,160 --> 01:14:55,520
PARTNER IN AREAS OF COMMON

1827
01:14:55,520 --> 01:14:56,800
INTEREST.

1828
01:14:56,800 --> 01:14:58,080
IT'S BEEN PARTICULARLY ENJOYABLE

1829
01:14:58,080 --> 01:15:00,160
TO MEET AND INTERACT WITH DR.

1830
01:15:00,160 --> 01:15:01,560
LANGEVIN, TO IDENTIFY MANY

1831
01:15:01,560 --> 01:15:08,520
SHARED INTERESTS AND NEW

1832
01:15:08,520 --> 01:15:09,080
COLLABORATIVE OPPORTUNITIES.

1833
01:15:09,080 --> 01:15:12,440
I'M GOING TO BEGIN WITH A BRIEF

1834
01:15:12,440 --> 01:15:13,880
INTRODUCTION TO NIAMS FOR THOSE

1835
01:15:13,880 --> 01:15:15,840
NOT FAMILIAR INCLUDING OUR

1836
01:15:15,840 --> 01:15:17,560
CURRENT BUDGET AND STRATEGIC

1837
01:15:17,560 --> 01:15:17,800
PLAN.

1838
01:15:17,800 --> 01:15:21,400
I'LL DISCUSS EXAMPLES OF NIAMS

1839
01:15:21,400 --> 01:15:23,680
INITIATIVES IN MUSCULOSKELETAL

1840
01:15:23,680 --> 01:15:24,480
PAIN, MANY CONDUCTED IN

1841
01:15:24,480 --> 01:15:25,920
PARTNERSHIP WITH OTHER

1842
01:15:25,920 --> 01:15:28,360
INSTITUTES AND CENTERS INCLUDING

1843
01:15:28,360 --> 01:15:28,560
NCCIH.

1844
01:15:28,560 --> 01:15:30,920
SO THE INSTITUTE WAS ESTABLISHED

1845
01:15:30,920 --> 01:15:32,680
IN 1986 BUT PREVIOUSLY PART OF

1846
01:15:32,680 --> 01:15:35,760
THE NATIONAL INSTITUTE OF

1847
01:15:35,760 --> 01:15:38,680
ARTHRITIS, DIABETES, DIGESTIVE

1848
01:15:38,680 --> 01:15:39,160
AND KIDNEY DISEASES, NOW

1849
01:15:39,160 --> 01:15:40,440
NATIONAL INSTITUTE OF DIABETES

1850
01:15:40,440 --> 01:15:42,360
AND DIGESTIVE AND KIDNEY

1851
01:15:42,360 --> 01:15:44,040
DISEASES, QUITE A MOUTHFUL.

1852
01:15:44,040 --> 01:15:47,600
AND MISSION OF NIAMS AS DR.

1853
01:15:47,600 --> 01:15:49,520
LANGEVIN WAS REFERRING TO

1854
01:15:49,520 --> 01:15:54,520
SUPPORT AN CONDUCT RESEARCH INTO

1855
01:15:54,520 --> 01:15:55,640
TREATMENT AND PREVENTION, TO

1856
01:15:55,640 --> 01:15:56,960
TRAIN THE NEXT GENERATION OF

1857
01:15:56,960 --> 01:15:59,120
SCIENTISTS TO CARRY OUT THIS

1858
01:15:59,120 --> 01:15:59,760
RESEARCH, AND PROVIDE

1859
01:15:59,760 --> 01:16:01,520
INFORMATION TO THE PUBLIC ABOUT

1860
01:16:01,520 --> 01:16:03,400
OUR RESEARCH PROGRESS AND

1861
01:16:03,400 --> 01:16:06,480
MISSION AREAS AND HOW IT CAN BE

1862
01:16:06,480 --> 01:16:08,760
APPLIED TO IMPROVE HEALTH.

1863
01:16:08,760 --> 01:16:19,440
IN 2020 NIAMS BUDGET WAS $624

1864
01:16:19,440 --> 01:16:20,400
MILLION, SUPPORTING INTRAMURAL

1865
01:16:20,400 --> 01:16:24,160
PROGRAM AND EXTRAMURAL RESEARCH 

1866
01:16:24,160 --> 01:16:27,360
THAT'S CONDUCTED AT INSTITUTIONS

1867
01:16:27,360 --> 01:16:28,600
AROUND THE COUNTRY.

1868
01:16:28,600 --> 01:16:29,800
WITH RESPECT TO THE BUDGET, THIS

1869
01:16:29,800 --> 01:16:33,480
SLIDE SHOWS THE BREAKDOWN OF

1870
01:16:33,480 --> 01:16:35,360
FISCAL YEAR 2020 FUNDING AMONG

1871
01:16:35,360 --> 01:16:36,560
INTRAMURAL, EXTRAMURAL, AND

1872
01:16:36,560 --> 01:16:39,600
OTHER COMPONENTS OF THE NIH AND

1873
01:16:39,600 --> 01:16:39,800
NIAMS.

1874
01:16:39,800 --> 01:16:42,800
LIKE THE REST OF NIH, NIAMS

1875
01:16:42,800 --> 01:16:45,520
INVESTS MOST MONEY AT

1876
01:16:45,520 --> 01:16:49,600
INSTITUTIONS AROUND THE COUNTRY,

1877
01:16:49,600 --> 01:16:50,800
10 1/2% TO INTRAMURAL RESEARCH

1878
01:16:50,800 --> 01:16:53,120
PROGRAM IN BETHESDA.

1879
01:16:53,120 --> 01:16:56,040
THE SLIGHT OF RMS, RESEARCH AND

1880
01:16:56,040 --> 01:17:01,920
MANAGEMENT SUPPORT, IS FOR WHAT 

1881
01:17:01,920 --> 01:17:02,840
OTHER ORGANIZATIONS CALL

1882
01:17:02,840 --> 01:17:03,360
OVERHEAD.

1883
01:17:03,360 --> 01:17:05,000
WITH INPUT FROM NIAMS ADVISORY

1884
01:17:05,000 --> 01:17:07,520
COUNCIL AND THE PUBLIC, NIAMS

1885
01:17:07,520 --> 01:17:11,000
DEVELOPED CURRENT STRATEGIC PLAN

1886
01:17:11,000 --> 01:17:13,600
COVERING FISCAL YEARS 2020-2024.

1887
01:17:13,600 --> 01:17:15,920
THE ULTIMATE GOAL TO DEVELOP

1888
01:17:15,920 --> 01:17:16,760
PATIENT-CENTERED PERSONALIZED

1889
01:17:16,760 --> 01:17:18,520
WAYS TO IMPROVE HEALTH OUTCOMES

1890
01:17:18,520 --> 01:17:21,520
IN THE FIVE CORE AREAS OF THE

1891
01:17:21,520 --> 01:17:23,680
NIAMS MISSION.

1892
01:17:23,680 --> 01:17:25,440
THESE INCLUDE SYSTEMIC RHEUMATIC

1893
01:17:25,440 --> 01:17:27,280
AND AUTOIMMUNE DISEASE, SKIN

1894
01:17:27,280 --> 01:17:29,720
BIOLOGY AND DISEASES, BONE

1895
01:17:29,720 --> 01:17:31,440
BIOLOGY AND DISEASES, MUSCLE

1896
01:17:31,440 --> 01:17:34,960
BIOLOGY AND DISEASES, AND JOINT

1897
01:17:34,960 --> 01:17:36,720
BIOLOGY, DISEASES, ORTHOPEDICS.

1898
01:17:36,720 --> 01:17:37,480
THE PLAN INCLUDES DEDICATED

1899
01:17:37,480 --> 01:17:39,520
SESSION FOR EACH OF THESE AREAS

1900
01:17:39,520 --> 01:17:40,360
INCLUDING BROAD RESEARCH

1901
01:17:40,360 --> 01:17:42,960
DIRECTIONS FOR TOPICS IN EACH OF

1902
01:17:42,960 --> 01:17:43,560
THE PORTFOLIOS.

1903
01:17:43,560 --> 01:17:45,680
IN LOOKING AT THE AREAS WITHIN

1904
01:17:45,680 --> 01:17:48,080
THE NIAMS PURVIEW I WANT TO

1905
01:17:48,080 --> 01:17:51,160
UNDERSCORE TREMENDOUS BURDEN OF 

1906
01:17:51,160 --> 01:17:52,320
THESE DISEASES.

1907
01:17:52,320 --> 01:17:53,560
ARTHRITIS AND MUSCULOSKELETAL

1908
01:17:53,560 --> 01:17:56,120
AFFECT PEOPLE OF ALL AGES AND

1909
01:17:56,120 --> 01:17:57,920
RACIAL AND ETHNIC BACKGROUNDS.

1910
01:17:57,920 --> 01:18:00,200
COMBINED THEY AFFECT TENS OF

1911
01:18:00,200 --> 01:18:01,960
MILLIONS OF AMERICANS, CAUSE

1912
01:18:01,960 --> 01:18:02,560
TREMENDOUS HUMAN SUFFERING,

1913
01:18:02,560 --> 01:18:04,560
AFFECT U.S. ECONOMY DUE TO

1914
01:18:04,560 --> 01:18:07,120
TREMENDOUS HEALTH CARE COSTS AND

1915
01:18:07,120 --> 01:18:08,160
LOSS OF PRODUCTIVITY.

1916
01:18:08,160 --> 01:18:10,520
MOST OF THE DISEASES COVERED BY

1917
01:18:10,520 --> 01:18:12,800
NIAMS ARE CHRONIC, AND MANY ALSO

1918
01:18:12,800 --> 01:18:15,000
ASSOCIATED WITH CHRONIC PAIN AND

1919
01:18:15,000 --> 01:18:15,480
DISABILITY.

1920
01:18:15,480 --> 01:18:17,520
MANY OF THEM WHETHER COMMON OR

1921
01:18:17,520 --> 01:18:24,120
RARE AFFECT WOMEN AND MINORITIES

1922
01:18:24,120 --> 01:18:24,520
DISPROPORTIONATELY.

1923
01:18:24,520 --> 01:18:26,960
THE CURRENT NIAMS STRATEGIC PLAN

1924
01:18:26,960 --> 01:18:27,720
IN ADDITION TO INCLUSION

1925
01:18:27,720 --> 01:18:29,360
INFORMATION SPECIFIC TO CORE

1926
01:18:29,360 --> 01:18:30,680
MISSION AREA ALSO HIGHLIGHTS

1927
01:18:30,680 --> 01:18:31,760
SEVERAL SCIENTIFIC THEMES THAT

1928
01:18:31,760 --> 01:18:34,400
CUT ACROSS ALL AREAS OF OUR

1929
01:18:34,400 --> 01:18:35,000
MISSION.

1930
01:18:35,000 --> 01:18:41,280
INCLUDING OUR EFFORTS RELATED TO

1931
01:18:41,280 --> 01:18:42,360
MUSCULOSKELETAL PAIN RESEARCH,

1932
01:18:42,360 --> 01:18:44,040
IDENTIFYING SHARED MECHANISMS IN

1933
01:18:44,040 --> 01:18:47,120
HEALTH AND AMONG DISEASES,

1934
01:18:47,120 --> 01:18:48,080
ADVANCING PATIENT CENTERED

1935
01:18:48,080 --> 01:18:51,040
APPROACHES, ADDRESSING HEALTH

1936
01:18:51,040 --> 01:18:52,440
NEEDS OF DIVERSE POPULATIONS,

1937
01:18:52,440 --> 01:18:54,400
ENABLING PRECISION MEDICINE TO

1938
01:18:54,400 --> 01:18:59,640
TAILOR CARE FOR EACH PATIENT.

1939
01:18:59,640 --> 01:19:00,880
BEFORE I DISCUSS NIAMS CURRENT

1940
01:19:00,880 --> 01:19:03,160
ACTIVITIES I WANT TO HIGHLIGHT A

1941
01:19:03,160 --> 01:19:05,240
SUCCESSFUL PAST COLLABORATION

1942
01:19:05,240 --> 01:19:08,640
BETWEEN NIAMS AND NCCIH.

1943
01:19:08,640 --> 01:19:11,880
IN 2004, NIAMS AND NCCIH LED A

1944
01:19:11,880 --> 01:19:13,960
TRANS-NIH-WIDE EFFORT TO DEVELOP

1945
01:19:13,960 --> 01:19:15,800
PATIENT-REPORTED OUTCOMES AND

1946
01:19:15,800 --> 01:19:16,600
MEASUREMENTS INFORMATION SYSTEM,

1947
01:19:16,600 --> 01:19:19,520
PROMIS, THAT WAS FUNDED THROUGH

1948
01:19:19,520 --> 01:19:21,840
NIH COMMON FUND.

1949
01:19:21,840 --> 01:19:22,840
WHILE PATIENT-REPORTED OUTCOMES

1950
01:19:22,840 --> 01:19:24,480
ARE WIDELY USED TODAY WHEN THE

1951
01:19:24,480 --> 01:19:27,400
PROGRAM BEGAN IN 2004 THERE WAS

1952
01:19:27,400 --> 01:19:29,280
A NEED FOR TOOLS TO ASSESS

1953
01:19:29,280 --> 01:19:30,800
PATIENT CENTERED OUTCOMES SUCH

1954
01:19:30,800 --> 01:19:33,040
AS PAIN IN CLINICAL RESEARCH.

1955
01:19:33,040 --> 01:19:36,320
TODAY PROMIS IS A RICH RESOURCE

1956
01:19:36,320 --> 01:19:38,480
FOR RESEARCHERS, CLINICIANS,

1957
01:19:38,480 --> 01:19:38,760
PATIENTS.

1958
01:19:38,760 --> 01:19:41,960
IT HAS APPROXIMATELY 70 DOMAINS

1959
01:19:41,960 --> 01:19:44,480
MEASURING PAIN, FATIGUE,

1960
01:19:44,480 --> 01:19:45,680
DEPRESSION, ANXIETY, SLEEP

1961
01:19:45,680 --> 01:19:46,800
DISTURBANCE, PHYSICAL FUNCTION,

1962
01:19:46,800 --> 01:19:48,640
AMONG OTHERS.

1963
01:19:48,640 --> 01:19:50,400
PROMIS IS VERY INCLUSIVE,

1964
01:19:50,400 --> 01:19:51,640
ENCOMPASSES CHILDREN AND ADULTS,

1965
01:19:51,640 --> 01:19:53,640
CAN BE ADMINISTERED TO A WIDE

1966
01:19:53,640 --> 01:19:56,400
RANGE OF INDIVIDUALS REGARDLESS

1967
01:19:56,400 --> 01:19:58,960
OF LITERACY, LANGUAGE, PHYSICAL

1968
01:19:58,960 --> 01:20:01,000
FUNCTION, LIFE COURSE.

1969
01:20:01,000 --> 01:20:05,360
THIS PARTNERSHIP IS ENHANCING

1970
01:20:05,360 --> 01:20:06,840
RESEARCH LANDSCAPE TO BRING

1971
01:20:06,840 --> 01:20:07,720
VOICES TO CLINICAL CARE AND

1972
01:20:07,720 --> 01:20:09,000
RESEARCH WITH THE GOAL OF

1973
01:20:09,000 --> 01:20:13,560
IMPROVING DAY TO DAY LIVES OF

1974
01:20:13,560 --> 01:20:13,960
PEOPLE.

1975
01:20:13,960 --> 01:20:16,880
NEXT I WANT TO DISCUSS SOME OF

1976
01:20:16,880 --> 01:20:20,480
NIAMS CURRENT ACTIVITIES TO

1977
01:20:20,480 --> 01:20:23,360
ADDRESS MUSCULOSKELETAL PAIN

1978
01:20:23,360 --> 01:20:26,080
BEGINNING WITH OAI, AN EXAMPLE

1979
01:20:26,080 --> 01:20:28,720
OF SIGNIFICANT EFFORTS IN

1980
01:20:28,720 --> 01:20:29,520
EXPLORING CLINICAL ASPECTS OF

1981
01:20:29,520 --> 01:20:31,120
OSTEOARTHRITIS AND REPRESENTS A

1982
01:20:31,120 --> 01:20:33,080
LONG-TERM INVESTMENT IN THE

1983
01:20:33,080 --> 01:20:33,320
FIELD.

1984
01:20:33,320 --> 01:20:35,000
THE INITIATIVE HAS BEEN CARRIED

1985
01:20:35,000 --> 01:20:36,880
OUT IN PARTNERSHIP WITH SEVERAL

1986
01:20:36,880 --> 01:20:39,760
NIH INSTITUTES AND CENTERS

1987
01:20:39,760 --> 01:20:44,800
INCLUDING NCCIH, FOUNDATION FOR

1988
01:20:44,800 --> 01:20:45,160
NIH, INDUSTRY.

1989
01:20:45,160 --> 01:20:51,520
STUDIED 4800 PARTICIPANTS FROM

1990
01:20:51,520 --> 01:20:52,960
45 TO 79.

1991
01:20:52,960 --> 01:20:54,960
58% WERE FEMALE.

1992
01:20:54,960 --> 01:20:56,240
PARTICIPANT VISITS THROUGH EIGHT

1993
01:20:56,240 --> 01:20:57,560
YEARS OF FOLLOW-UP COMPLETED

1994
01:20:57,560 --> 01:20:59,760
MAKES THE OAI ONE OF THE LARGEST

1995
01:20:59,760 --> 01:21:00,960
AND PERHAPS MOST IMPORTANT

1996
01:21:00,960 --> 01:21:03,920
DATASETS IN THE HISTORY OF

1997
01:21:03,920 --> 01:21:05,880
OSTEOARTHRITIS RESEARCH.

1998
01:21:05,880 --> 01:21:08,360
THE DATASET CONTAINS CLINICAL,

1999
01:21:08,360 --> 01:21:11,000
GENOMIC, PATIENT-REPORT AND

2000
01:21:11,000 --> 01:21:12,200
FUNCTIONAL DATA, BIOLOGICAL

2001
01:21:12,200 --> 01:21:14,360
SPECIMENS, X-RAY AND MAGNETIC

2002
01:21:14,360 --> 01:21:15,480
RESONANCE IMAGES.

2003
01:21:15,480 --> 01:21:20,560
THE DATA ARE FREELY AVAILABLE AT

2004
01:21:20,560 --> 01:21:20,880
OAI.NIH.GOV.

2005
01:21:20,880 --> 01:21:23,360
RESEARCHERS CAN ACCESS THE

2006
01:21:23,360 --> 01:21:25,200
STUDIES OF NATURAL HISTORY,

2007
01:21:25,200 --> 01:21:27,200
BIOMARKERS, RISK FACTORS FOR

2008
01:21:27,200 --> 01:21:28,720
O.A. RISK AND PROGRESSION.

2009
01:21:28,720 --> 01:21:31,520
DATA ARE ALSO RESOURCED FOR

2010
01:21:31,520 --> 01:21:32,640
INVESTIGATORS FOR COMPUTATIONAL

2011
01:21:32,640 --> 01:21:33,960
MACHINE LEARNING EXPERTISE IN

2012
01:21:33,960 --> 01:21:36,800
OTHER FIELDS TO APPLY BIG DATA

2013
01:21:36,800 --> 01:21:38,360
THOUGHTS TO A BIOMEDICAL

2014
01:21:38,360 --> 01:21:39,960
RESEARCH PROGRAM.

2015
01:21:39,960 --> 01:21:42,040
TO DATE MORE THAN 680

2016
01:21:42,040 --> 01:21:43,520
PEER-REVIEWED PAPERS HAVE BEEN

2017
01:21:43,520 --> 01:21:45,200
PUBLISHED USING OAI DATA.

2018
01:21:45,200 --> 01:21:50,960
OVER ALL THE OAI HAS TAUGHT US

2019
01:21:50,960 --> 01:21:53,400
KNEE O.A. INVOLVES ALL THE

2020
01:21:53,400 --> 01:21:56,680
STRUCTURES THAT FORM THE JOINT.

2021
01:21:56,680 --> 01:21:58,360
THIS SLIDE PROVIDES EXAMPLES OF

2022
01:21:58,360 --> 01:22:00,320
RESEARCH ADVANCES FROM THE OAI

2023
01:22:00,320 --> 01:22:02,040
RELATED TO PHYSICAL ACTIVITY AND

2024
01:22:02,040 --> 01:22:02,520
DIET.

2025
01:22:02,520 --> 01:22:04,560
THE STUDY HAS BEEN PROVIDED

2026
01:22:04,560 --> 01:22:05,880
VALUABLE INFORMATION ABOUT

2027
01:22:05,880 --> 01:22:07,800
POTENTIALLY MODIFIABLE RISK

2028
01:22:07,800 --> 01:22:08,880
FACTORS FOR OSTEOARTHRITIS.

2029
01:22:08,880 --> 01:22:10,680
THESE FINDINGS HAVE IMPORTANT

2030
01:22:10,680 --> 01:22:11,960
PUBLIC HEALTH PRELIMINARY

2031
01:22:11,960 --> 01:22:12,840
INDICATIONS.

2032
01:22:12,840 --> 01:22:15,200
FOR EXAMPLE WE HAVE EVIDENCE

2033
01:22:15,200 --> 01:22:16,520
EXERCISE IS SAFE AND BENEFICIAL

2034
01:22:16,520 --> 01:22:20,280
FOR INDIVIDUALS WITH O.A.

2035
01:22:20,280 --> 01:22:21,920
BEYOND OAI, OTHER NIAMS-FUNDED

2036
01:22:21,920 --> 01:22:23,680
STUDIES DOCUMENTED THAT WEIGHT

2037
01:22:23,680 --> 01:22:28,200
LOSS AND EXERCISE CAN IMPROVE 

2038
01:22:28,200 --> 01:22:29,360
KNEE O.A. SYMPTOMS.

2039
01:22:29,360 --> 01:22:31,120
AS I NOTED IN MY INTRODUCTION,

2040
01:22:31,120 --> 01:22:32,440
HEALTH DISPARITIES ARE SEEN IN

2041
01:22:32,440 --> 01:22:35,800
MANY OF THE DISEASES WITHIN OUR

2042
01:22:35,800 --> 01:22:37,160
MISSION, INCLUDING

2043
01:22:37,160 --> 01:22:37,600
OSTEOARTHRITIS.

2044
01:22:37,600 --> 01:22:39,320
THIS IS A SIGNIFICANT PUBLIC

2045
01:22:39,320 --> 01:22:40,360
HEALTH CHALLENGE SINCE O.A. IS

2046
01:22:40,360 --> 01:22:43,040
THE MOST COMMON TYPE OF

2047
01:22:43,040 --> 01:22:44,400
ARTHRITIS LEADING TO DISABILITY.

2048
01:22:44,400 --> 01:22:46,520
NIAMS IS PLANNING A WORKSHOP ON

2049
01:22:46,520 --> 01:22:48,920
HEALTH DISPARITIES AND O.A.,

2050
01:22:48,920 --> 01:22:55,680
AJERCH  -- THE AGENDA ON THE

2051
01:22:55,680 --> 01:22:57,120
SLIDE, TIMELY CONSIDERING

2052
01:22:57,120 --> 01:23:02,760
PRIORITIES REGARDING HEALTH 

2053
01:23:02,760 --> 01:23:03,160
DISPARITIES.

2054
01:23:03,160 --> 01:23:06,160
THE WORKSHOP WILL BRING TOGETHER

2055
01:23:06,160 --> 01:23:07,360
O.A. INVESTIGATORS WITH EXPERTS

2056
01:23:07,360 --> 01:23:09,640
IN HEALTH DISPARITIES RESEARCH

2057
01:23:09,640 --> 01:23:11,080
TO EXCHANGE IDEAS ABOUT WIDE

2058
01:23:11,080 --> 01:23:12,280
DISPARITIES IN TREATMENT

2059
01:23:12,280 --> 01:23:13,560
OUTCOMES AND ACCESS TO CARE

2060
01:23:13,560 --> 01:23:17,160
EXIST AND HOW THEY CAN BE

2061
01:23:17,160 --> 01:23:17,440
ADDRESSED.

2062
01:23:17,440 --> 01:23:21,480
PARTICIPANTS WILL CONSIDER HOW 

2063
01:23:21,480 --> 01:23:23,200
INTEGRATION OF BEHAVIORAL AND

2064
01:23:23,200 --> 01:23:26,000
BIOMEDICAL SCIENCE COULD LEAD TO

2065
01:23:26,000 --> 01:23:29,880
BETTER HEALTH IN O.A.

2066
01:23:29,880 --> 01:23:37,960
NEXT I WANT TO TALK ABOUT THE 

2067
01:23:37,960 --> 01:23:41,480
NIAMS-FUNDED METEOR TRIAL.

2068
01:23:41,480 --> 01:23:44,520
MENISCAL TEAR, WHEN THE DISC IS

2069
01:23:44,520 --> 01:23:47,640
DAMAGED, OCCURS FREQUENTLY AMONG

2070
01:23:47,640 --> 01:23:50,440
INDIVIDUALS WITH KNEE

2071
01:23:50,440 --> 01:23:51,360
OSTEOARTHRITIS.

2072
01:23:51,360 --> 01:23:55,800
PATIENTS HAVE TWO OPTIONS FOR

2073
01:23:55,800 --> 01:24:01,560
TREATMENT. 

2074
01:24:01,560 --> 01:24:04,400
ARTHROSCOPIC PARTIAL MENISECTOMY

2075
01:24:04,400 --> 01:24:07,960
AND STABILIZING, OR PHYSICAL

2076
01:24:07,960 --> 01:24:09,520
THERAPY.

2077
01:24:09,520 --> 01:24:11,160
IN METEOR, RESEARCHERS COMPARED

2078
01:24:11,160 --> 01:24:11,960
SURGERY WITH PHYSICAL THERAPY,

2079
01:24:11,960 --> 01:24:13,240
TO DETERMINE IF ONE TREATMENT

2080
01:24:13,240 --> 01:24:17,640
LED TO BETTER OUTCOMES THAN THE

2081
01:24:17,640 --> 01:24:17,840
OTHER.

2082
01:24:17,840 --> 01:24:19,160
THEY RECRUITED APPROXIMATELY 350

2083
01:24:19,160 --> 01:24:21,160
MEN AND WOMEN, AGES 45 AND

2084
01:24:21,160 --> 01:24:22,880
OLDER, WITH MILD TO MODERATE

2085
01:24:22,880 --> 01:24:29,960
KNEE O.A. AND MENISCAL TEAR.

2086
01:24:29,960 --> 01:24:30,760
PATIENTS WERE RANDOMLY ASSIGNED

2087
01:24:30,760 --> 01:24:31,680
TO RECEIVE SURGERY AND PHYSICAL

2088
01:24:31,680 --> 01:24:33,360
THERAPY OR PHYSICAL THERAPY

2089
01:24:33,360 --> 01:24:33,560
ALONE.

2090
01:24:33,560 --> 01:24:34,280
PATIENTS ASSIGNED TO PHYSICAL

2091
01:24:34,280 --> 01:24:35,840
THERAPY HAD THE OPTION OF

2092
01:24:35,840 --> 01:24:39,400
UNDERGOING SURGERY LATER IN THE

2093
01:24:39,400 --> 01:24:39,600
TRIAL.

2094
01:24:39,600 --> 01:24:41,160
THE RESEARCHERS ASSESSED EACH

2095
01:24:41,160 --> 01:24:43,320
PATIENT'S PROGRESS OVER ONE

2096
01:24:43,320 --> 01:24:44,400
YEAR, TRACKING IMPROVEMENTS IN

2097
01:24:44,400 --> 01:24:47,280
FUNCTIONAL STATUS AND PAIN

2098
01:24:47,280 --> 01:24:48,080
LEVELS.

2099
01:24:48,080 --> 01:24:51,760
INITIALLY, THERE WAS GREATER 

2100
01:24:51,760 --> 01:24:55,560
IMPROVEMENT IN THOSE WITH

2101
01:24:55,560 --> 01:24:55,800
SURGERY.

2102
01:24:55,800 --> 01:24:57,440
THOSE IN THE PHYSICAL THERAPY

2103
01:24:57,440 --> 01:25:03,400
THROUGH 12 CONTINUES IMPROVEMENT

2104
01:25:03,400 --> 01:25:04,640
SHOWED IMPROVEMENT COMPARABLE TO

2105
01:25:04,640 --> 01:25:06,520
SURGERY.

2106
01:25:06,520 --> 01:25:07,600
IT'S OKAY TO TRY PHYSICAL

2107
01:25:07,600 --> 01:25:08,720
THERAPY FIRST IF A PATIENT

2108
01:25:08,720 --> 01:25:08,960
PREFERS.

2109
01:25:08,960 --> 01:25:11,080
A THIRD OF PATIENTS ASSIGNED TO

2110
01:25:11,080 --> 01:25:12,920
PHYSICAL THERAPY ALONE UNDERWENT

2111
01:25:12,920 --> 01:25:14,240
SURGERY WITHIN SIX MONTHS,

2112
01:25:14,240 --> 01:25:15,320
INDICATING PHYSICAL THERAPY IS

2113
01:25:15,320 --> 01:25:19,720
NOT THE ANSWER FOR SOME

2114
01:25:19,720 --> 01:25:20,160
PATIENTS.

2115
01:25:20,160 --> 01:25:21,800
THE ORIGINAL METEOR STUDY DID

2116
01:25:21,800 --> 01:25:23,840
NOT ADDRESS IMPORTANT ISSUE OF

2117
01:25:23,840 --> 01:25:25,640
LONG-TERM OUTCOMES OF SURGERY

2118
01:25:25,640 --> 01:25:29,160
VERSUS PHYSICAL THERAPY. 

2119
01:25:29,160 --> 01:25:32,800
PRELIMINARY DATA FROM METEOR

2120
01:25:32,800 --> 01:25:34,360
SUGGESTED SURGERY WITH RAPID

2121
01:25:34,360 --> 01:25:35,560
PROGRESSION AS ASSESSED THROUGH

2122
01:25:35,560 --> 01:25:36,880
MRI THROUGH FIVE YEARS,

2123
01:25:36,880 --> 01:25:38,760
RESEARCHERS ARE NOW CONDUCTING A

2124
01:25:38,760 --> 01:25:40,120
12-YEAR FOLLOW-UP STUDY TO

2125
01:25:40,120 --> 01:25:41,800
DETERMINE WHETHER THIS MORE

2126
01:25:41,800 --> 01:25:42,760
RAPID STRUCTURAL PROGRESSION

2127
01:25:42,760 --> 01:25:45,760
CONTINUES TO BE SEEN OVER LONGER

2128
01:25:45,760 --> 01:25:49,200
TIME PERIOD.

2129
01:25:49,200 --> 01:25:51,160
THE RESEARCHERS HOPE TO

2130
01:25:51,160 --> 01:25:55,560
UNDERSTAND CLINICAL 

2131
01:25:55,560 --> 01:25:56,640
IMPLICATIONS.

2132
01:25:56,640 --> 01:25:57,560
ASSUMPTION THAT FASTER

2133
01:25:57,560 --> 01:25:59,280
PROGRESSION ON MRI RESULTS IN

2134
01:25:59,280 --> 01:26:00,280
MORE PAIN, MORE EVIDENCE IS

2135
01:26:00,280 --> 01:26:01,360
NEEDED TO KNOW WHETHER THIS IS

2136
01:26:01,360 --> 01:26:02,200
THE CASE.

2137
01:26:02,200 --> 01:26:03,640
WE EXPECT THIS RESEARCH WILL

2138
01:26:03,640 --> 01:26:05,960
PROVIDE IMPORTANT NEW

2139
01:26:05,960 --> 01:26:07,360
INFORMATION FOR CLINICIANS AND

2140
01:26:07,360 --> 01:26:09,120
PATIENTS TO UNDERSTAND RISKS AND

2141
01:26:09,120 --> 01:26:14,120
BENEFITS OF SURGERY VERSUS

2142
01:26:14,120 --> 01:26:14,640
NON-OPERATIVE TREATMENT.

2143
01:26:14,640 --> 01:26:16,960
NEXT I'LL TALK ABOUT A COUPLE

2144
01:26:16,960 --> 01:26:19,680
NIAMS RESEARCH ACTIVITIES

2145
01:26:19,680 --> 01:26:21,200
RELATED TO FIBROMYALGIA, WHERE

2146
01:26:21,200 --> 01:26:24,640
PAIN AND INCREASED PAIN 

2147
01:26:24,640 --> 01:26:25,840
SENSITIVITY ARE KEY FEATURES.

2148
01:26:25,840 --> 01:26:30,840
IT IS MORE OFTEN  DIAGNOSED IN

2149
01:26:30,840 --> 01:26:34,240
WOMEN BUT CAN OCCUR IN CHILDREN,

2150
01:26:34,240 --> 01:26:36,440
YOU'VE NIGHT ONSET FIBROMYALGIA,

2151
01:26:36,440 --> 01:26:38,160
A PAINFUL CONDITION PERSISTING

2152
01:26:38,160 --> 01:26:41,760
INTO ADULTHOOD FOR MANY

2153
01:26:41,760 --> 01:26:43,440
PATIENTS.

2154
01:26:43,440 --> 01:26:45,760
BUILDING ON PREVIOUS RESEARCH

2155
01:26:45,760 --> 01:26:49,920
SHOWING CBT BENEFITS ADOLESCENTS

2156
01:26:49,920 --> 01:26:51,000
WITH FIBROMYALGIA, THE

2157
01:26:51,000 --> 01:26:52,680
NIAMS-FUNDED FIBROMYALGIA

2158
01:26:52,680 --> 01:26:54,080
INTEGRATIVE TRAINING PROGRAM FOR

2159
01:26:54,080 --> 01:26:56,040
TEENS, FIT TEENS, IS A CLINICAL

2160
01:26:56,040 --> 01:26:58,160
TRIAL TESTING WHETHER ADDING

2161
01:26:58,160 --> 01:27:00,520
PHYSICAL ACTIVITY TO CBT

2162
01:27:00,520 --> 01:27:02,320
CONIFERS ADDITIONAL BENEFIT IN

2163
01:27:02,320 --> 01:27:06,120
TERMS OF MANAGING PAIN IN

2164
01:27:06,120 --> 01:27:07,640
ADOLESCENCE, SUPPLEMENTING WITH

2165
01:27:07,640 --> 01:27:09,040
NEUROMUSCULAR TRAINING EXERCISES

2166
01:27:09,040 --> 01:27:12,200
DERIVED FROM PEDIATRIC INJURY

2167
01:27:12,200 --> 01:27:13,520
PREVENTION RESEARCH.

2168
01:27:13,520 --> 01:27:16,360
PILOT DATA SUGGESTED FIT TEENS

2169
01:27:16,360 --> 01:27:17,640
INTERVENTION OFFERINGS STRONGER

2170
01:27:17,640 --> 01:27:18,760
TREATMENT BENEFITS THAN CBT

2171
01:27:18,760 --> 01:27:23,760
ALONE WITH RESPECT TO PAIN

2172
01:27:23,760 --> 01:27:25,960
REDUCTION, RESULTS REMAIN TO BE

2173
01:27:25,960 --> 01:27:28,880
CONFIRMED IN A LARGER STUDY.

2174
01:27:28,880 --> 01:27:29,840
NIAMS IS INVESTING IN

2175
01:27:29,840 --> 01:27:33,760
FIBROMYALGIA RESEARCH THROUGH 

2176
01:27:33,760 --> 01:27:35,560
CENTERS OF RESEARCH TRANSLATION

2177
01:27:35,560 --> 01:27:38,200
PROGRAM, TEAM SCIENCE PERHAPS

2178
01:27:38,200 --> 01:27:44,000
ARE DESIGNED TO ADDRESS

2179
01:27:44,000 --> 01:27:45,240
TRANSLATIONAL CHALLENGES.

2180
01:27:45,240 --> 01:27:46,080
NIAMS-SUPPORTED CORE AT THE

2181
01:27:46,080 --> 01:27:49,000
UNIVERSITY OF MICHIGAN SEEKS TO

2182
01:27:49,000 --> 01:27:49,680
IMPROVE UNDERSTANDING TO

2183
01:27:49,680 --> 01:27:52,520
TREATMENTS FOR PAIN SUCH AS

2184
01:27:52,520 --> 01:27:53,840
SURGERY OR MEDICATIONS.

2185
01:27:53,840 --> 01:27:54,920
THIS IS IMPORTANT BECAUSE

2186
01:27:54,920 --> 01:27:55,560
INDIVIDUAL RESPONSES TO

2187
01:27:55,560 --> 01:27:57,640
TREATMENTS FOR PAIN ARE HIGHLY

2188
01:27:57,640 --> 01:27:58,080
VARIABLE.

2189
01:27:58,080 --> 01:27:59,600
NO MATTER HOW SUCCESSFUL THE

2190
01:27:59,600 --> 01:28:02,200
TREATMENT MAY APPEAR TO BE BY

2191
01:28:02,200 --> 01:28:04,000
CLINICAL MEASURES.

2192
01:28:04,000 --> 01:28:05,000
FOR EXAMPLE, MANY INDIVIDUALS

2193
01:28:05,000 --> 01:28:07,200
WITH CHRONIC PAIN WHO UNDERGO

2194
01:28:07,200 --> 01:28:09,440
SURGERY FOR THE PROBLEM CONTINUE

2195
01:28:09,440 --> 01:28:12,360
TO EXPERIENCE PAIN DESPITE WHAT

2196
01:28:12,360 --> 01:28:13,560
MAY BE CONSIDERED EXCELLENT

2197
01:28:13,560 --> 01:28:15,560
RESULTS FROM A CLINICAL

2198
01:28:15,560 --> 01:28:15,880
STANDPOINT.

2199
01:28:15,880 --> 01:28:17,760
JUST AS SOME WITH AUTOIMMUNE

2200
01:28:17,760 --> 01:28:19,600
DISORDERS CONTINUE TO HAVE PAIN

2201
01:28:19,600 --> 01:28:21,280
AFTER INFLAMMATION IS WELL

2202
01:28:21,280 --> 01:28:23,200
CONTROLLED WITH BIOLOGICS OR

2203
01:28:23,200 --> 01:28:24,480
OTHER TREATMENT.

2204
01:28:24,480 --> 01:28:25,840
THE RESEARCHERS WILL DETERMINE

2205
01:28:25,840 --> 01:28:28,560
IF THIS VARIABILITY CAN BE

2206
01:28:28,560 --> 01:28:29,960
QUANTIFIED OR PREDICTED USING

2207
01:28:29,960 --> 01:28:36,520
FIBROMYALGIA PAIN SCALE AS A 

2208
01:28:36,520 --> 01:28:36,920
SURROGATE MEASURE.

2209
01:28:36,920 --> 01:28:38,120
HIGHER SCORES COULD PREDICT MORE

2210
01:28:38,120 --> 01:28:40,760
PAIN FROM THE CENTRAL NERVOUS

2211
01:28:40,760 --> 01:28:41,560
SYSTEM.

2212
01:28:41,560 --> 01:28:44,280
THEY ARE EXPLORING WHETHER THE

2213
01:28:44,280 --> 01:28:46,360
PHENOTYPE HAS CLINICAL AND

2214
01:28:46,360 --> 01:28:48,480
NEUROBIOLOGICAL FEATURES SIMILAR

2215
01:28:48,480 --> 01:28:53,360
TO FIBROMYALGIA EVEN WHEN

2216
01:28:53,360 --> 01:28:54,440
COMORBID WITH OTHER

2217
01:28:54,440 --> 01:28:57,360
MUSCULOSKELETAL PAIN CONDITIONS

2218
01:28:57,360 --> 01:28:59,760
WITH DIFFERENT PAIN MECHANISMS.

2219
01:28:59,760 --> 01:29:00,360
BY BETTER UNDERSTANDING

2220
01:29:00,360 --> 01:29:01,880
UNDERLYING MECHANISMS ASSOCIATED

2221
01:29:01,880 --> 01:29:03,680
WITH PAIN FOR SEVERAL

2222
01:29:03,680 --> 01:29:05,280
CONDITIONS, THIS RESEARCH PLAY

2223
01:29:05,280 --> 01:29:06,360
ENABLE A MORE PERSONALIZED

2224
01:29:06,360 --> 01:29:12,760
APPROACH TO PAIN MANAGEMENT FOR

2225
01:29:12,760 --> 01:29:13,200
PATIENTS.

2226
01:29:13,200 --> 01:29:19,120
NEXT I WANT TO TALK ABOUT

2227
01:29:19,120 --> 01:29:20,120
"HEAL."

2228
01:29:20,120 --> 01:29:21,640
IT'S A TRANSAGENCY EFFORT TO

2229
01:29:21,640 --> 01:29:24,280
SPEED SOLUTIONS TO STEM THE

2230
01:29:24,280 --> 01:29:25,880
NATIONAL OPIOID PUBLIC HEALTH

2231
01:29:25,880 --> 01:29:26,120
CRISIS.

2232
01:29:26,120 --> 01:29:28,240
IT'S FUNDING HUNDREDS OF

2233
01:29:28,240 --> 01:29:29,040
PROJECTS ACROSS THE NATION,

2234
01:29:29,040 --> 01:29:32,400
RESEARCHERS ARE TAKING A VARIETY

2235
01:29:32,400 --> 01:29:34,320
OF APPROACHES TO TACKLE OPIOID

2236
01:29:34,320 --> 01:29:35,960
EPIDEMIC THROUGH UNDERSTANDING,

2237
01:29:35,960 --> 01:29:37,560
MANAGING, TREATING PAIN AND

2238
01:29:37,560 --> 01:29:40,000
IMPROVING TREATMENT FOR OPIOID

2239
01:29:40,000 --> 01:29:41,200
MISUSE AND ADDICTION.

2240
01:29:41,200 --> 01:29:42,600
ALMOST EVERY NIH INSTITUTE AND

2241
01:29:42,600 --> 01:29:47,120
CENTER IS PARTICIPATING IN

2242
01:29:47,120 --> 01:29:47,360
"HEAL."

2243
01:29:47,360 --> 01:29:49,600
ONE OF THE WAYS NIAMS IS

2244
01:29:49,600 --> 01:29:51,920
CONTRIBUTING IS LEADING BACK

2245
01:29:51,920 --> 01:29:52,840
PAIN CONSORTIUM RESEARCH

2246
01:29:52,840 --> 01:29:53,520
PROGRAM, BACPAC.

2247
01:29:53,520 --> 01:29:55,080
CHRONIC LOW BACK PAIN IS ONE OF

2248
01:29:55,080 --> 01:29:57,520
THE MOST COMMON FORMS OF CHRONIC

2249
01:29:57,520 --> 01:29:59,840
PAIN AMONG ADULTS WORLDWIDE.

2250
01:29:59,840 --> 01:30:01,320
ACCORDING TO THE 2010 GLOBAL

2251
01:30:01,320 --> 01:30:03,160
BURDEN OF DISEASE STUDY, IT

2252
01:30:03,160 --> 01:30:05,240
RANKED HIGHEST IN TERMS OF YEARS

2253
01:30:05,240 --> 01:30:07,560
LIVED WITH DISABILITY AMONG

2254
01:30:07,560 --> 01:30:09,480
HUNDREDS OF CONDITIONS.

2255
01:30:09,480 --> 01:30:10,920
CURRENTS TREATMENT OPTIONS ARE

2256
01:30:10,920 --> 01:30:12,960
INEFFECTIVE LEADING TO INCREASED

2257
01:30:12,960 --> 01:30:14,760
USE OF OPIOIDS.

2258
01:30:14,760 --> 01:30:17,000
BACPAC IS A TRANSLATIONAL

2259
01:30:17,000 --> 01:30:18,760
PATIENT-CENTERED RESEARCH EFFORT

2260
01:30:18,760 --> 01:30:19,640
TO DEVELOP EFFECTIVE,

2261
01:30:19,640 --> 01:30:21,360
PERSONALIZED TREATMENTS FOR

2262
01:30:21,360 --> 01:30:23,360
CHRONIC LOW BACK PAIN.

2263
01:30:23,360 --> 01:30:25,240
THROUGH BACPAC, INVESTIGATORS

2264
01:30:25,240 --> 01:30:26,760
ARE USING DEEP PHENOTYPING TO

2265
01:30:26,760 --> 01:30:27,840
CHARACTERIZE PEOPLE WITH CHRONIC

2266
01:30:27,840 --> 01:30:29,800
LOW BACK PAIN TO IMPROVE

2267
01:30:29,800 --> 01:30:32,960
UNDERSTANDING OF THE COMPLEX

2268
01:30:32,960 --> 01:30:34,080
MECHANISMS UNDERLYING THE

2269
01:30:34,080 --> 01:30:35,800
CONDITION, IDENTIFYING PATHWAYS

2270
01:30:35,800 --> 01:30:38,120
AND TARGETS FOR INTERVENTION, TO

2271
01:30:38,120 --> 01:30:39,880
INFORM DEVELOPMENT OF THERAPIES

2272
01:30:39,880 --> 01:30:43,560
THAT REDUCE PAIN AND IMPROVE

2273
01:30:43,560 --> 01:30:45,240
FUNCTION, DEVELOPING PRECISE

2274
01:30:45,240 --> 01:30:46,320
DIAGNOSTIC AND TREATMENT

2275
01:30:46,320 --> 01:30:48,240
ALGORITHMS, AND THEN TESTING AND

2276
01:30:48,240 --> 01:30:49,440
REFINING THEM IN CLINICAL TRIALS

2277
01:30:49,440 --> 01:30:52,880
SO THAT HEALTH CARE PROVIDERS

2278
01:30:52,880 --> 01:30:55,840
CAN TAILOR THERAPIES TO

2279
01:30:55,840 --> 01:30:57,480
PATIENTS, COMBINING DATA FROM

2280
01:30:57,480 --> 01:31:00,120
TRANSLATIONAL RESEARCH, PHASED

2281
01:31:00,120 --> 01:31:02,120
CLINICAL TRIALS TO DELIVER

2282
01:31:02,120 --> 01:31:03,720
INTEGRATIVE MODEL TO PACK BANE

2283
01:31:03,720 --> 01:31:05,360
AND COLLABORATING WITH "HEAL"'S

2284
01:31:05,360 --> 01:31:08,200
EARLY PHASE PAIN INVESTIGATION

2285
01:31:08,200 --> 01:31:10,520
CLINICAL NETWORK, EPPIC NET, TO

2286
01:31:10,520 --> 01:31:12,360
TEST POTENTIAL CHRONIC LOW BACK

2287
01:31:12,360 --> 01:31:16,160
PAIN INTERVENTIONS IN CLINICAL

2288
01:31:16,160 --> 01:31:16,760
TRIALS.

2289
01:31:16,760 --> 01:31:17,960
THIS SLIDE PROVIDES ADDITIONAL

2290
01:31:17,960 --> 01:31:20,360
INFORMATION ABOUT THE COMPONENTS

2291
01:31:20,360 --> 01:31:22,720
OF BACPAC AND INVESTIGATORS

2292
01:31:22,720 --> 01:31:25,040
LEADING THE VARIOUS EFFORTS.

2293
01:31:25,040 --> 01:31:26,280
THE MECHANISTIC AND RESEARCH

2294
01:31:26,280 --> 01:31:27,800
CENTERS ARE COLLECTING PATIENT

2295
01:31:27,800 --> 01:31:29,360
DATA TO IDENTIFY SPECIFIC TRAITS

2296
01:31:29,360 --> 01:31:31,840
UNIQUE TO CHRONIC LOW BACK PAIN

2297
01:31:31,840 --> 01:31:35,560
PATIENTS, AND IDENTIFY NEW

2298
01:31:35,560 --> 01:31:36,320
THERAPIES.

2299
01:31:36,320 --> 01:31:38,400
THE TECHNOLOGY SITES CREATE,

2300
01:31:38,400 --> 01:31:40,360
TEST, AND DISTRIBUTE TECHNOLOGY

2301
01:31:40,360 --> 01:31:42,360
AND METHODS TO TEST, QUANTIFY

2302
01:31:42,360 --> 01:31:45,400
AND RELIEVE CHRONIC LOWER BACK

2303
01:31:45,400 --> 01:31:46,160
PAIN.

2304
01:31:46,160 --> 01:31:48,120
PHASE 2 CLINICAL STUDIES ASSESS

2305
01:31:48,120 --> 01:31:50,960
SAFETY AND VALUE OF ALTERNATIVE

2306
01:31:50,960 --> 01:31:52,120
MEDICINE, NON-ADDICTIVE DRUGS,

2307
01:31:52,120 --> 01:31:53,960
DEVICES THAT RELIEVE CHRONIC LOW

2308
01:31:53,960 --> 01:31:55,560
BACK PAIN AND HELP PATIENT CARRY

2309
01:31:55,560 --> 01:31:58,120
OUT ACTIVITIES OF DAILY LIVING.

2310
01:31:58,120 --> 01:32:01,520
THE NEW THERAPIES UNDER STUDY

2311
01:32:01,520 --> 01:32:03,680
USE BIOLOGY, PSYCHOLOGY,

2312
01:32:03,680 --> 01:32:04,680
INFORMATION ON SOCIAL FACTORS

2313
01:32:04,680 --> 01:32:06,200
CONNECTED TO CHRONIC LOWER BACK

2314
01:32:06,200 --> 01:32:07,320
PAIN.

2315
01:32:07,320 --> 01:32:10,120
AND THE DATA INTEGRATION

2316
01:32:10,120 --> 01:32:13,720
ALGORITHM DEVELOPMENT AND

2317
01:32:13,720 --> 01:32:15,800
OPERATION CENTER COORDINATES

2318
01:32:15,800 --> 01:32:17,760
BACPAC ACTIVITIES.

2319
01:32:17,760 --> 01:32:20,040
A CONSORTIUM-WIDE CLINICAL TRIAL

2320
01:32:20,040 --> 01:32:22,360
CALLED BIOMARKERS FOR EVALUATING

2321
01:32:22,360 --> 01:32:23,640
SPINE TREATMENTS, BEST, IS

2322
01:32:23,640 --> 01:32:24,920
DESIGNED TO INFORM PRECISION

2323
01:32:24,920 --> 01:32:26,920
MEDICINE APPROACH TO CHRONIC LOW

2324
01:32:26,920 --> 01:32:29,600
BACK PAIN.

2325
01:32:29,600 --> 01:32:31,880
IT IS INVESTIGATING MIND-BODY

2326
01:32:31,880 --> 01:32:33,360
INTERVENTIONS, NOT POWERED BASED

2327
01:32:33,360 --> 01:32:35,520
ON ASSESSING EFFICACY OF ONE

2328
01:32:35,520 --> 01:32:36,240
VERSUS ANOTHER INTERVENTION BUT

2329
01:32:36,240 --> 01:32:39,160
SEEKS TO LINK A PATIENT'S

2330
01:32:39,160 --> 01:32:40,200
PHENOTYPE TO INTERVENTION THAT

2331
01:32:40,200 --> 01:32:46,200
WORKS BEST FOR THAT INDIVIDUAL.

2332
01:32:46,200 --> 01:32:48,520
USING DATA FROM THE BACPAC

2333
01:32:48,520 --> 01:32:49,800
RESEARCH PROGRAMS CLINICAL

2334
01:32:49,800 --> 01:32:52,800
STUDIES, THE DATA CENTER WILL

2335
01:32:52,800 --> 01:32:54,120
ALSO DEVELOP PATIENT-CENTERED

2336
01:32:54,120 --> 01:32:56,840
ALGORITHMS TO IMPROVE

2337
01:32:56,840 --> 01:32:57,600
THERAPEUTIC INTERVENTIONS AND

2338
01:32:57,600 --> 01:32:59,960
PROVIDE INTEGRATED MODEL OF

2339
01:32:59,960 --> 01:33:01,640
CHRONIC LOW BACK PAIN.

2340
01:33:01,640 --> 01:33:03,720
WE BEGAN WITH INITIAL MODEL

2341
01:33:03,720 --> 01:33:05,040
BASED ON CURRENT STATE OF

2342
01:33:05,040 --> 01:33:05,480
KNOWLEDGE.

2343
01:33:05,480 --> 01:33:08,520
AS YOU CAN SEE, MODEL IS FOCUSED

2344
01:33:08,520 --> 01:33:12,680
ON TAKING INTEGRATIVE APPROACH

2345
01:33:12,680 --> 01:33:14,120
THAT ENCOMPASSES BIOLOGICAL,

2346
01:33:14,120 --> 01:33:15,800
BIOMECHANICAL, PSYCHOSOCIAL AND

2347
01:33:15,800 --> 01:33:17,360
OTHER PROCESSES.

2348
01:33:17,360 --> 01:33:18,880
THROUGH BACPAC WE WILL

2349
01:33:18,880 --> 01:33:23,360
INTERROGATE IMPLIED 

2350
01:33:23,360 --> 01:33:25,680
R ELATIONSHIPS IN ITERATIVE

2351
01:33:25,680 --> 01:33:26,680
FASHION, REVISE USING DATA

2352
01:33:26,680 --> 01:33:29,960
GENERATED OR AVAILABLE TO

2353
01:33:29,960 --> 01:33:30,160
BACPAC.

2354
01:33:30,160 --> 01:33:31,920
WE'RE DELIGHTED TO BE ABLE TO

2355
01:33:31,920 --> 01:33:33,440
PLAY AN IMPORTANT ROLE IN

2356
01:33:33,440 --> 01:33:34,240
ADDRESSING THE PROBLEM OF

2357
01:33:34,240 --> 01:33:36,280
CHRONIC LOW BACK PAIN WHILE

2358
01:33:36,280 --> 01:33:38,800
WORKING WITH PARTNERS INCLUDING

2359
01:33:38,800 --> 01:33:40,200
NCCIH ON THIS TRANS-NIH EFFORT

2360
01:33:40,200 --> 01:33:44,160
TO ADDRESS THE NATION'S OPIOID

2361
01:33:44,160 --> 01:33:44,960
EPIDEMIC.

2362
01:33:44,960 --> 01:33:46,440
IN ADDITION TO PACKBACK, NIAMS

2363
01:33:46,440 --> 01:33:47,640
ALSO WORKED WITH SEVERAL

2364
01:33:47,640 --> 01:33:50,720
INSTITUTES AND CENTERS ON A NEW

2365
01:33:50,720 --> 01:33:52,000
HEAL INITIATIVE, RESTORING JOINT

2366
01:33:52,000 --> 01:33:54,880
AND FUNCTION TO REDUCE PAIN

2367
01:33:54,880 --> 01:33:56,720
CONSORTIUM, RE-JOIN.

2368
01:33:56,720 --> 01:33:57,960
THE FUNDING OPPORTUNITY

2369
01:33:57,960 --> 01:33:59,560
ANNOUNCEMENTS WERE RELEASED LAST

2370
01:33:59,560 --> 01:34:00,000
WEEK.

2371
01:34:00,000 --> 01:34:01,200
SINCE DR. LANGEVIN WILL BE

2372
01:34:01,200 --> 01:34:02,760
DISCUSSING THIS PROGRAM LATER

2373
01:34:02,760 --> 01:34:03,720
THIS AFTERNOON, I'LL JUST

2374
01:34:03,720 --> 01:34:08,760
BRIEFLY NOTE THE GOAL IS TO

2375
01:34:08,760 --> 01:34:11,120
DEFINE INNERVATION OF DIFFERENT

2376
01:34:11,120 --> 01:34:15,800
TISSUES THAT FORM THE JOINT.

2377
01:34:15,800 --> 01:34:17,760
IN ADDITION TO BACPAC AND

2378
01:34:17,760 --> 01:34:18,760
RE-JOIN, NIAMS IS PARTNERING

2379
01:34:18,760 --> 01:34:22,560
WITH SEVERAL I.C.s ON OTHER

2380
01:34:22,560 --> 01:34:23,560
HEAL INITIATIVES.

2381
01:34:23,560 --> 01:34:26,560
THIS COUNCIL IS LIKELY FAMILIAR

2382
01:34:26,560 --> 01:34:28,560
WITH THE NCCIH-LED INITIATIVE

2383
01:34:28,560 --> 01:34:30,360
DEVELOPING QUANTITATIVE IMAGING

2384
01:34:30,360 --> 01:34:32,360
AND OTHER RELEVANT BIOMARKERS

2385
01:34:32,360 --> 01:34:33,880
AND MYOFASCIAL TISSUES FOR

2386
01:34:33,880 --> 01:34:34,680
CLINICAL PAIN MANAGEMENT, AND

2387
01:34:34,680 --> 01:34:36,360
NIAMS IS PLEASED TO BE PARTNER

2388
01:34:36,360 --> 01:34:38,760
IN THIS EFFORT WHICH SEEKS TO

2389
01:34:38,760 --> 01:34:39,880
IMPROVE MONITORING OF RESPONSES

2390
01:34:39,880 --> 01:34:43,320
AND PREDICTION OF OUTCOMES OF

2391
01:34:43,320 --> 01:34:45,000
VARIOUS PAIN MANAGEMENT

2392
01:34:45,000 --> 01:34:45,800
REGIMENS.

2393
01:34:45,800 --> 01:34:50,160
WE ARE ALSO INVOLVED IN A

2394
01:34:50,160 --> 01:34:51,240
NIDA-LED INITIATIVE FOR BEST

2395
01:34:51,240 --> 01:34:53,880
MODELS OF CARE AS WELL AS

2396
01:34:53,880 --> 01:34:55,400
IMPROVE ACCESS TO QUALITY CARE

2397
01:34:55,400 --> 01:34:57,960
FOR PATIENTS WITH CHRONIC PAIN

2398
01:34:57,960 --> 01:35:02,960
AND OPIOID USE DISORDER, OPIOID

2399
01:35:02,960 --> 01:35:07,440
MISUSE. 

2400
01:35:07,440 --> 01:35:10,040
NIAMS CONTRIBUTED TO NCCIH--LED

2401
01:35:10,040 --> 01:35:11,000
WORKSHOP IN 2020.

2402
01:35:11,000 --> 01:35:12,960
THREE PROJECTS RELATED TO NIAMS

2403
01:35:12,960 --> 01:35:14,720
MISSION AREAS OF ACUPUNCTURE IN

2404
01:35:14,720 --> 01:35:16,000
CHRONIC LOW BACK PAIN,

2405
01:35:16,000 --> 01:35:21,040
MINDFULNESS FOR CHRONIC LOW BACK

2406
01:35:21,040 --> 01:35:22,080
PAIN, AND PHYSICAL THERAPY ARE

2407
01:35:22,080 --> 01:35:26,960
SUPPORTED AS PART OF THE "HEAL"

2408
01:35:26,960 --> 01:35:28,920
PRISM EFFORT, FOR MANAGEMENT OF

2409
01:35:28,920 --> 01:35:35,560
PAIN TO REDUCE OPIOID

2410
01:35:35,560 --> 01:35:36,360
PRESCRIBING.

2411
01:35:36,360 --> 01:35:40,200
NIAMS AND NCCIH PARTNERED ON A

2412
01:35:40,200 --> 01:35:40,960
LARGE PRAGMATIC CLUSTER

2413
01:35:40,960 --> 01:35:41,960
RANDOMIZED CONTROLLED TRIAL

2414
01:35:41,960 --> 01:35:44,800
TESTING EFFECTIVENESS OF A

2415
01:35:44,800 --> 01:35:47,160
SIMPLE AND INEXPENSIVE

2416
01:35:47,160 --> 01:35:47,520
INTERVENTION.

2417
01:35:47,520 --> 01:35:48,760
INSERTING EPIDEMIOLOGIC

2418
01:35:48,760 --> 01:35:50,360
BENCHMARKS INTO LUMBAR SPINE

2419
01:35:50,360 --> 01:35:51,080
IMAGING REPORTS.

2420
01:35:51,080 --> 01:35:53,600
THE GOAL WAS TO TEST WHETHER THE

2421
01:35:53,600 --> 01:35:56,400
ADDITION OF SUCH DATA REDUCED

2422
01:35:56,400 --> 01:35:58,760
SUBSEQUENT TESTS AND TREATMENTS

2423
01:35:58,760 --> 01:35:59,640
INCLUDING CROSS-SECTIONAL

2424
01:35:59,640 --> 01:36:01,960
IMAGING, SUCH AS MAGNETIC

2425
01:36:01,960 --> 01:36:06,400
RESONANCE AND COMPUTED

2426
01:36:06,400 --> 01:36:07,960
TOMOGRAPHY, OPIOID PRESCRIPTION,

2427
01:36:07,960 --> 01:36:10,120
SPINAL INJECTION, OR SURGERY.

2428
01:36:10,120 --> 01:36:14,560
LAST YEAR THE INVESTIGATORS

2429
01:36:14,560 --> 01:36:15,760
CONCLUDED THAT INSERTING

2430
01:36:15,760 --> 01:36:18,200
EPIDEMIOLOGIC TEXT HAD NO EFFECT

2431
01:36:18,200 --> 01:36:21,720
ON WHETHER NEW NON-OPIOID

2432
01:36:21,720 --> 01:36:22,760
PAIN-RELATED MEDICATIONS WERE

2433
01:36:22,760 --> 01:36:23,680
PRESCRIBED OVERALL, BUT WAS

2434
01:36:23,680 --> 01:36:26,200
ASSOCIATED WITH NUMBER OF NEW

2435
01:36:26,200 --> 01:36:27,360
PRESCRIPTIONS FOR CERTAIN

2436
01:36:27,360 --> 01:36:33,760
NON-OPIOID SUBCLASSES SUCH AS 

2437
01:36:33,760 --> 01:36:34,600
NSAIDs AND TRICYCLIC

2438
01:36:34,600 --> 01:36:34,960
ANTIDEPRESSANTS.

2439
01:36:34,960 --> 01:36:36,920
NOW I'LL TURN TO SOME OF OUR

2440
01:36:36,920 --> 01:36:39,360
EFFORTS RELATED TO CONDITIONS

2441
01:36:39,360 --> 01:36:40,840
WITHIN OUR SYSTEMIC RHEUMATIC

2442
01:36:40,840 --> 01:36:44,360
DISEASES PORTFOLIO, MANY ARE

2443
01:36:44,360 --> 01:36:45,000
ALSO CHARACTERIZED BY

2444
01:36:45,000 --> 01:36:45,880
MUSCULOSKELETAL PAIN.

2445
01:36:45,880 --> 01:36:48,360
ONE OF THE INITIAL PROJECTS

2446
01:36:48,360 --> 01:36:50,920
LAUNCHED BY THE NIH ACCELERATING

2447
01:36:50,920 --> 01:36:52,000
MEDICINES PARTNERSHIP PROGRAM,

2448
01:36:52,000 --> 01:36:54,360
AMP, WAS IN RHEUMATOID ARTHRITIS

2449
01:36:54,360 --> 01:36:54,760
AND LUPUS.

2450
01:36:54,760 --> 01:36:58,600
I WANT TO DISCUSS THE PROGRAM

2451
01:36:58,600 --> 01:37:02,360
AND TELL YOU ABOUT THE NEXT

2452
01:37:02,360 --> 01:37:04,280
ITERATION WHICH WE EXPECT TO BE

2453
01:37:04,280 --> 01:37:05,000
FUNDED SOON.

2454
01:37:05,000 --> 01:37:12,880
IN 2014, NIAMS AND NIAID WITH

2455
01:37:12,880 --> 01:37:13,960
ORGANIZATIONS LAUNCHED AMP-RA

2456
01:37:13,960 --> 01:37:16,240
LUPUS PROGRAM TO TRANSFORM THE

2457
01:37:16,240 --> 01:37:17,360
MODEL FOR DEVELOPING DIAGNOSTICS

2458
01:37:17,360 --> 01:37:20,200
AND TREATMENTS FOR THESE

2459
01:37:20,200 --> 01:37:20,760
CONDITIONS.

2460
01:37:20,760 --> 01:37:22,080
THE PROJECT WAS EXTREMELY

2461
01:37:22,080 --> 01:37:23,920
INNOVATIVE IN THAT IT INVOLVED

2462
01:37:23,920 --> 01:37:26,560
ISOLATION OF SINGLE CELLS FROM

2463
01:37:26,560 --> 01:37:36,520
TISSUES, SITES OF DISEASE FOR 

2464
01:37:36,520 --> 01:37:37,360
ANALYSIS, SURPASSING

2465
01:37:37,360 --> 01:37:38,680
EXPECTATIONS BY IDENTIFYING CELL

2466
01:37:38,680 --> 01:37:39,760
TYPES AND PATHWAYS NOT

2467
01:37:39,760 --> 01:37:41,200
IDENTIFIED BEFORE IN THESE

2468
01:37:41,200 --> 01:37:46,240
CONDITIONS AND ADVANCING NEW 

2469
01:37:46,240 --> 01:37:47,040
ANALYTIC APPROACHES FOR STUDYING

2470
01:37:47,040 --> 01:37:48,080
DISEASE IN HUMAN TISSUES.

2471
01:37:48,080 --> 01:37:50,200
ONE OF THE MOST IMPORTANT

2472
01:37:50,200 --> 01:37:53,640
LEGACIES OF THE PROGRAM IS THE

2473
01:37:53,640 --> 01:37:54,640
RICH DATASET IT GENERATE AND

2474
01:37:54,640 --> 01:37:57,040
MADE AVAILABLE TO THE RESEARCH

2475
01:37:57,040 --> 01:37:58,680
COMMUNITY.

2476
01:37:58,680 --> 01:38:00,440
WE ENVISION THE PROGRAM WILL

2477
01:38:00,440 --> 01:38:03,760
BENEFIT RESEARCH ON RA LUPUS

2478
01:38:03,760 --> 01:38:05,480
INCLUDING RESEARCH SUPPORTED BY

2479
01:38:05,480 --> 01:38:05,680
NCCIH.

2480
01:38:05,680 --> 01:38:08,520
FOR EXAMPLE, THE DATA MAY BE

2481
01:38:08,520 --> 01:38:09,920
USEFUL FOR RESEARCHERS EXPLORING

2482
01:38:09,920 --> 01:38:12,640
POTENTIAL OF NATURAL PRODUCTS

2483
01:38:12,640 --> 01:38:15,040
WITH PROPOSED ANTI-INFLAMMATORY

2484
01:38:15,040 --> 01:38:16,200
PROPERTIES IN MUSCULOSKELETAL

2485
01:38:16,200 --> 01:38:17,960
AND INFLAMMATORY CONDITIONS.

2486
01:38:17,960 --> 01:38:19,160
IN ADDITION, BIOMARKERS ARE NOT

2487
01:38:19,160 --> 01:38:21,560
A MAJOR FOCUS OF THE AMP, ANY

2488
01:38:21,560 --> 01:38:24,200
NEW BIOMARKERS THAT DO RESULT

2489
01:38:24,200 --> 01:38:26,040
COULD BE USED TO ENHANCED DESIGN

2490
01:38:26,040 --> 01:38:29,120
OF CLINICAL TRIALS AND CLINICAL

2491
01:38:29,120 --> 01:38:29,760
STUDIES THAT TEST COMPLEMENTARY

2492
01:38:29,760 --> 01:38:33,720
INTERVENTIONS IN TERMS OF BETTER

2493
01:38:33,720 --> 01:38:38,560
OUTCOME MEASURES AND PATIENT

2494
01:38:38,560 --> 01:38:39,160
STRATIFICATION.

2495
01:38:39,160 --> 01:38:40,760
WHEREAS AMP RA-LUPUS IDENTIFIED

2496
01:38:40,760 --> 01:38:41,560
CELL POPULATIONS AND EFFECTOR

2497
01:38:41,560 --> 01:38:45,480
PATHWAYS THAT CAN BE USED AS

2498
01:38:45,480 --> 01:38:47,160
BIOMARKERS, THERAPEUTIC TARGETS

2499
01:38:47,160 --> 01:38:48,920
OR BENCHMARKS FOR MOLECULAR

2500
01:38:48,920 --> 01:38:51,760
CLASSIFICATION OF DISEASE, THE

2501
01:38:51,760 --> 01:38:55,160
NEXT PHASE CALLED AMP AIM FOR

2502
01:38:55,160 --> 01:38:55,880
AUTOIMMUNE AND IMMUNE-MEDIATED

2503
01:38:55,880 --> 01:38:58,320
DISEASE, WILL PUT THESE PIECES

2504
01:38:58,320 --> 01:38:59,520
BACK TOGETHER, TO DISCOVER HOW

2505
01:38:59,520 --> 01:39:02,360
CELLS OF THE INNATE AND ADAPTIVE

2506
01:39:02,360 --> 01:39:03,760
IMMUNE SYSTEM AND TISSUE

2507
01:39:03,760 --> 01:39:05,560
RESIDENT CELLS INTERACT TO CAUSE

2508
01:39:05,560 --> 01:39:08,040
INFLAMMATION AND DISEASE AND TO

2509
01:39:08,040 --> 01:39:12,280
ACCELERATE DISCOVERY OF DISEASE 

2510
01:39:12,280 --> 01:39:13,480
MECHANISMS IN THERAPEUTIC

2511
01:39:13,480 --> 01:39:14,360
TARGETS.

2512
01:39:14,360 --> 01:39:17,400
AS THE NAME IMPLIES, AMP AIM

2513
01:39:17,400 --> 01:39:18,280
EXTENDS BEYOND RHEUMATOID

2514
01:39:18,280 --> 01:39:20,680
ARTHRITIS AND LUPUS.

2515
01:39:20,680 --> 01:39:27,560
REQUEST FOR APPLICATIONS 

2516
01:39:27,560 --> 01:39:29,800
INCLUDED PSORIASIS, PSORIATIC

2517
01:39:29,800 --> 01:39:31,520
ARTHRITIS AND SHÖGREN'S SYSTEM.

2518
01:39:31,520 --> 01:39:38,280
WE EXPECT TO USE AN  ANALYTICS

2519
01:39:38,280 --> 01:39:40,560
TO HELP IDENTIFY SPECIFIC AND

2520
01:39:40,560 --> 01:39:42,200
SHARED DISEASE MECHANISMS.

2521
01:39:42,200 --> 01:39:44,520
ULTIMATELY WE OPEN IT WILL

2522
01:39:44,520 --> 01:39:47,880
PROVIDE A ROAD MAP HOW TO APPLY

2523
01:39:47,880 --> 01:39:50,320
TECHNOLOGY TO STUDY DISEASE

2524
01:39:50,320 --> 01:39:50,960
TISSUES.

2525
01:39:50,960 --> 01:39:52,720
WE EXPECT THE PROJECT TO RESULT

2526
01:39:52,720 --> 01:39:54,680
IN KNOWLEDGE AND DATA PORTAL TO

2527
01:39:54,680 --> 01:39:56,680
ENABLE DATA SHARING AND MAKE

2528
01:39:56,680 --> 01:39:58,960
DATA AND ANALYTIC TOOLS

2529
01:39:58,960 --> 01:40:00,240
ACCESSIBLE TO ALL STAKEHOLDERS.

2530
01:40:00,240 --> 01:40:02,560
WE HOPE WHAT WE LEARNED FROM AMP

2531
01:40:02,560 --> 01:40:06,280
AIM WILL HELP TO ADVANCE

2532
01:40:06,280 --> 01:40:07,840
INTEGRATEIVE APPROACHES TO

2533
01:40:07,840 --> 01:40:08,640
PATHOPHYSIOLOGY AND TREATMENTS

2534
01:40:08,640 --> 01:40:10,680
IN OF DISEASES BEING STUDIES.

2535
01:40:10,680 --> 01:40:14,000
WE'VE REVIEWED  APPLICATIONS AND

2536
01:40:14,000 --> 01:40:18,760
EXPECT TO ANNOUNCE THE AWARDS IN

2537
01:40:18,760 --> 01:40:19,760
THE COMING WEEKS.

2538
01:40:19,760 --> 01:40:21,160
NOW THAT I'VE SHARED INFORMATION

2539
01:40:21,160 --> 01:40:23,160
ABOUT OUR CURRENT ACTIVITIES I

2540
01:40:23,160 --> 01:40:25,800
WANT TO BRIEFLY COVER OUR BUDGET

2541
01:40:25,800 --> 01:40:26,840
OUTLOOK AND FUTURE PLANS.

2542
01:40:26,840 --> 01:40:28,480
AS YOU KNOW, THE NEW FISCAL YEAR

2543
01:40:28,480 --> 01:40:30,920
FOR THE FEDERAL GOVERNMENT BEGAN

2544
01:40:30,920 --> 01:40:32,000
ON OCTOBER 1.

2545
01:40:32,000 --> 01:40:34,080
THE PRESIDENT AND BOTH CHAMBERS

2546
01:40:34,080 --> 01:40:35,480
OF CONGRESS PROPOSED BUDGETS FOR

2547
01:40:35,480 --> 01:40:37,040
THE NIH AND NIAMS, THE CONGRESS

2548
01:40:37,040 --> 01:40:39,240
HAS NOT YET REACHED AN AGREEMENT

2549
01:40:39,240 --> 01:40:41,200
ON THE FINAL NUMBERS.

2550
01:40:41,200 --> 01:40:45,360
WE'RE CURRENTLY OPERATING UNDER

2551
01:40:45,360 --> 01:40:45,960
CONTINUING RESOLUTION THROUGH

2552
01:40:45,960 --> 01:40:46,280
FEBRUARY 18.

2553
01:40:46,280 --> 01:40:49,800
WE DON'T KNOW WHAT THE FINAL

2554
01:40:49,800 --> 01:40:52,440
BUDGETS FOR 2022 LOOK LIKE WE'RE

2555
01:40:52,440 --> 01:40:53,640
ENCOURAGING BY FUNDING LEVELS IN

2556
01:40:53,640 --> 01:40:55,960
THE PROPOSALS.

2557
01:40:55,960 --> 01:40:59,760
AMONG THE PROPOSALS IS INCREASE

2558
01:40:59,760 --> 01:41:03,320
FOR "HEAL," BUDGET PROPOSALS

2559
01:41:03,320 --> 01:41:05,160
ALSO INCREASE ADDITIONAL $24

2560
01:41:05,160 --> 01:41:11,000
MILLION TO ENHANCE NIAMS PAIN

2561
01:41:11,000 --> 01:41:12,600
AND OPIOID AND RESEARCH

2562
01:41:12,600 --> 01:41:15,000
PORTFOLIO, TO INVEST MONEY

2563
01:41:15,000 --> 01:41:17,240
SHOULD IT BE INCLUDED.

2564
01:41:17,240 --> 01:41:18,880
RELATED WE PUBLISHED A NOTICE OF

2565
01:41:18,880 --> 01:41:21,760
SPECIAL INTEREST TO HIGHLIGHT

2566
01:41:21,760 --> 01:41:23,040
INTEREST IN PROMOTING RESEARCH

2567
01:41:23,040 --> 01:41:28,360
ON PAIN.

2568
01:41:28,360 --> 01:41:30,720
WE'RE OPTIMISTIC AND EXPECT THEY

2569
01:41:30,720 --> 01:41:32,560
WILL BENEFIT INDIVIDUALS AND

2570
01:41:32,560 --> 01:41:36,560
FAMILIES LIVING BY AND IMPACTED

2571
01:41:36,560 --> 01:41:37,800
BY MUSCULOSKELETAL PAIN.

2572
01:41:37,800 --> 01:41:39,360
I LEAVE YOU WITH RESOURCES TO

2573
01:41:39,360 --> 01:41:40,320
LEARN MORE ABOUT NIAMS.

2574
01:41:40,320 --> 01:41:41,960
IF YOU'RE INTERESTED IN LEARNING

2575
01:41:41,960 --> 01:41:43,720
MORE ABOUT OUR PROGRAMS, VISIT

2576
01:41:43,720 --> 01:41:45,120
THE NIAMS WEBSITE.

2577
01:41:45,120 --> 01:41:47,960
YOU CAN FIND US ON FACEBOOK,

2578
01:41:47,960 --> 01:41:48,160
YouTube.

2579
01:41:48,160 --> 01:41:51,120
TO LEARN MORE ABOUT OUR FUNDING

2580
01:41:51,120 --> 01:41:52,680
OPPORTUNITY ANNOUNCEMENTS AS

2581
01:41:52,680 --> 01:41:54,920
WELL AS NOTICES ANNOUNCING

2582
01:41:54,920 --> 01:41:56,360
SPECIAL INTERESTS, SUBSCRIBE TO

2583
01:41:56,360 --> 01:41:59,760
THE NEWSLETTER AND FOLLOW OUR

2584
01:41:59,760 --> 01:42:00,760
TWITTER ACCOUNT.

2585
01:42:00,760 --> 01:42:01,600
ONCE AGAIN, I THANK YOU VERY

2586
01:42:01,600 --> 01:42:03,040
MUCH FOR THE OPPORTUNITY TO

2587
01:42:03,040 --> 01:42:04,760
PRESENT TO THIS COUNCIL AND

2588
01:42:04,760 --> 01:42:06,040
WOULD BE HAPPY TO TAKE QUESTIONS

2589
01:42:06,040 --> 01:42:11,720
AT THIS TIME. .

2590
01:42:11,720 --> 01:42:14,600
>> THANK YOU, DR. CRISWELL.

2591
01:42:14,600 --> 01:42:17,240
WE'RE NOW OPEN FOR EXTENDED

2592
01:42:17,240 --> 01:42:18,960
QUESTIONS, QUESTIONS AND ANSWERS

2593
01:42:18,960 --> 01:42:20,640
AND DISCUSSIONS FOR ANYTHING

2594
01:42:20,640 --> 01:42:23,360
BETWEEN COUNCIL AND DR. CHRIS

2595
01:42:23,360 --> 01:42:23,720
WELL.

2596
01:42:23,720 --> 01:42:25,160
RAISE YOUR DIGITAL HAND.

2597
01:42:25,160 --> 01:42:27,120
I WILL CALL ON YOU IN THE ORDER

2598
01:42:27,120 --> 01:42:32,560
YOU RAISE YOUR HANDS.

2599
01:42:32,560 --> 01:42:34,840
DR. LANGEVIN, DID YOU WANT TO

2600
01:42:34,840 --> 01:42:35,560
MAKE OPENING REMARKS?

2601
01:42:35,560 --> 01:42:35,800
>> YES.

2602
01:42:35,800 --> 01:42:37,240
I WOULD VERY MUCH LIKE TO.

2603
01:42:37,240 --> 01:42:41,400
I WANT TO REALLY THANK YOU FOR

2604
01:42:41,400 --> 01:42:43,840
THIS WONDERFUL OVERVIEW OF ALL

2605
01:42:43,840 --> 01:42:49,600
OF THE INTEREST, THE BROAD

2606
01:42:49,600 --> 01:42:50,520
INTEREST OF NIAMS, BUT I'M

2607
01:42:50,520 --> 01:42:53,360
STRUCK BY THE AREAS OF NOT ONLY

2608
01:42:53,360 --> 01:42:56,400
HISTORICAL COLLABORATIONS THAT

2609
01:42:56,400 --> 01:42:59,440
WE'VE HAD BETWEEN NCCIH AND

2610
01:42:59,440 --> 01:43:02,360
NIAMS BUT THE POTENTIAL FOR THE

2611
01:43:02,360 --> 01:43:02,960
FUTURE.

2612
01:43:02,960 --> 01:43:07,880
THIS IS VERY EXCITING AND I LOOK

2613
01:43:07,880 --> 01:43:09,680
FORWARD TO HEARING ANY REACTIONS

2614
01:43:09,680 --> 01:43:13,400
FROM OUR COUNCIL ABOUT WHAT THEY

2615
01:43:13,400 --> 01:43:18,600
FIND INTERESTING IN HERE AND 

2616
01:43:18,600 --> 01:43:19,880
WHAT THEY SEE.

2617
01:43:19,880 --> 01:43:22,480
>> I WAS ALSO REALLY STRUCK BY

2618
01:43:22,480 --> 01:43:24,000
THE TREMENDOUS OVERLAP AND LONG

2619
01:43:24,000 --> 01:43:25,960
HISTORY OF OUR COLLABORATIONS IN

2620
01:43:25,960 --> 01:43:27,960
PREPARING THESE REMARKS.

2621
01:43:27,960 --> 01:43:30,080
SO REALLY MANY, MANY

2622
01:43:30,080 --> 01:43:30,960
OPPORTUNITIES MOVING FORWARD,

2623
01:43:30,960 --> 01:43:37,360
VERY EXCITED ABOUT THAT. 

2624
01:43:37,360 --> 01:43:37,760
>> ABSOLUTELY.

2625
01:43:37,760 --> 01:43:38,800
>> DR. DELEDO AND DR. HARRIS.

2626
01:43:38,800 --> 01:43:41,400
>> I'LL BE VERY SHORT.

2627
01:43:41,400 --> 01:43:47,480
A PERSON WHO STRADDLED NIAMS AND

2628
01:43:47,480 --> 01:43:49,480
NCCIH, NONE OF THIS IS NEWS FOR

2629
01:43:49,480 --> 01:43:49,920
ME.

2630
01:43:49,920 --> 01:43:53,640
THERE'S ALWAYS BEEN OVERLAP AND

2631
01:43:53,640 --> 01:43:56,280
I'VE BEEN PLEASED WITH HOW

2632
01:43:56,280 --> 01:43:57,360
THERE'S JUST SO MUCH

2633
01:43:57,360 --> 01:43:58,680
COLLABORATION ALREADY.

2634
01:43:58,680 --> 01:44:02,200
I THINK THERE'S POTENTIAL FOR A 

2635
01:44:02,200 --> 01:44:06,760
GREAT DEAL MORE.

2636
01:44:06,760 --> 01:44:10,120
>> THANK YOU.

2637
01:44:10,120 --> 01:44:11,360
>> DR. HARRIS?

2638
01:44:11,360 --> 01:44:12,880
>> THANK YOU VERY MUCH, DR.

2639
01:44:12,880 --> 01:44:14,360
CRISWELL, FOR YOUR PRESENTATION.

2640
01:44:14,360 --> 01:44:16,880
AND VERY EXCITED ABOUT THE

2641
01:44:16,880 --> 01:44:17,160
POTENTIALS.

2642
01:44:17,160 --> 01:44:19,560
I WONDER IF THERE'S A WAY TO

2643
01:44:19,560 --> 01:44:21,360
STRENGTHEN THE PARTNERING

2644
01:44:21,360 --> 01:44:24,760
BETWEEN NIAMS AND NCCIH TO HAVE

2645
01:44:24,760 --> 01:44:25,680
SPECIFIC FUNDING OPPORTUNITIES

2646
01:44:25,680 --> 01:44:28,480
THAT BRIDGE BOTH, YOU KNOW,

2647
01:44:28,480 --> 01:44:29,600
INTEGRATIVE MEDICINE APPROACHES

2648
01:44:29,600 --> 01:44:31,440
THAT MANY PATIENTS ARE TRYING

2649
01:44:31,440 --> 01:44:32,600
AND MORE CONVENTIONAL APPROACHES

2650
01:44:32,600 --> 01:44:35,600
WHICH MAY BE MUCH MORE EASILY

2651
01:44:35,600 --> 01:44:37,000
ACCESSIBLE TO PATIENTS, AND I'M

2652
01:44:37,000 --> 01:44:40,960
WONDERING IF THERE MIGHT BE ANY

2653
01:44:40,960 --> 01:44:42,320
OPPORTUNITIES TO STRENGTHEN THE

2654
01:44:42,320 --> 01:44:44,280
BRIDGE WHERE THERE'S SPECIFIC

2655
01:44:44,280 --> 01:44:46,560
RFAs OR SPECIFIC ITEMS FOR

2656
01:44:46,560 --> 01:44:48,960
FUNDING THAT BRIDGE THAT

2657
01:44:48,960 --> 01:44:50,280
TRANSLATIONAL GAP.

2658
01:44:50,280 --> 01:44:52,160
BECAUSE MANY TIMES IN HEALTH

2659
01:44:52,160 --> 01:44:53,360
CARE SETTINGS, IT'S SILOED.

2660
01:44:53,360 --> 01:44:56,080
LIKE YOU EITHER GET INTEGRATEIVE

2661
01:44:56,080 --> 01:44:57,080
APPROACH FOR CONVENTIONAL

2662
01:44:57,080 --> 01:44:59,160
APPROACH AND MANY TIMES YOU

2663
01:44:59,160 --> 01:45:01,000
DON'T GET SYNERGY BETWEEN THOSE,

2664
01:45:01,000 --> 01:45:02,720
ALTHOUGH THERE ARE SOME PATIENTS

2665
01:45:02,720 --> 01:45:04,160
THAT ARE FORTUNATE ENOUGH TO GET

2666
01:45:04,160 --> 01:45:04,520
THAT.

2667
01:45:04,520 --> 01:45:07,000
I'M WONDERING IF THERE'S ANY

2668
01:45:07,000 --> 01:45:10,000
FUNDING TO SEEK THAT SYNERGY.

2669
01:45:10,000 --> 01:45:13,320
>> FIRST OF ALL, THAT'S A REALLY

2670
01:45:13,320 --> 01:45:13,960
INTERESTING COMMENT.

2671
01:45:13,960 --> 01:45:18,960
YOU KNOW, MUCH OF THE RESEARCH

2672
01:45:18,960 --> 01:45:19,720
OPERATES INDEPENDENTLY IN

2673
01:45:19,720 --> 01:45:23,240
PARALLEL IN SILOS AS YOU MENTION

2674
01:45:23,240 --> 01:45:24,760
BUT PATIENTS WANT TO ACCESS

2675
01:45:24,760 --> 01:45:26,640
ANYTHING THAT MIGHT HELP ACROSS

2676
01:45:26,640 --> 01:45:27,720
THE SPECTRUM.

2677
01:45:27,720 --> 01:45:30,440
AND IT ISN'T COMMON TO SEE THESE

2678
01:45:30,440 --> 01:45:31,960
THINGS BROUGHT TOGETHER.

2679
01:45:31,960 --> 01:45:34,520
I'M STILL LEARNING ABOUT ALL OF

2680
01:45:34,520 --> 01:45:36,160
THE DIFFERENT WAYS TO PARTNER

2681
01:45:36,160 --> 01:45:37,360
WITH INSTITUTES TO FUND

2682
01:45:37,360 --> 01:45:38,760
RESEARCH, BUT I'M SURE THAT AT

2683
01:45:38,760 --> 01:45:41,360
LEAST FROM A PATIENT STANDPOINT

2684
01:45:41,360 --> 01:45:43,680
AND FROM STANDPOINT OF GAPS IN

2685
01:45:43,680 --> 01:45:45,000
CURRENT RESEARCH, YOU TOUCHED

2686
01:45:45,000 --> 01:45:47,400
UPON A REALLY IMPORTANT AREA

2687
01:45:47,400 --> 01:45:48,600
THAT, YOU KNOW, REPRESENTS A

2688
01:45:48,600 --> 01:45:52,040
PERFECT PLACE FOR NIAMS AND

2689
01:45:52,040 --> 01:45:53,200
NCCIH TO COME TOGETHER.

2690
01:45:53,200 --> 01:45:55,560
SO APPRECIATE THAT SUGGESTION

2691
01:45:55,560 --> 01:45:56,160
AND SEARCH SOMETHING DR.

2692
01:45:56,160 --> 01:45:58,160
LANGEVIN AND I CAN BRAINSTORM

2693
01:45:58,160 --> 01:45:59,120
ABOUT MOVING FORWARD.

2694
01:45:59,120 --> 01:46:07,200
THANK YOU FOR THAT COMMENT.

2695
01:46:07,200 --> 01:46:10,760
>> DR. MALING AND DR. CHERMER.

2696
01:46:10,760 --> 01:46:13,400
>> I WANT TO COMMENT I THINK AT

2697
01:46:13,400 --> 01:46:21,560
LEAST THREE OF PARTICIPANTS IN 

2698
01:46:21,560 --> 01:46:24,120
OUR NIH MEETING HERE, ARE PART

2699
01:46:24,120 --> 01:46:26,760
OF THE BACPAC, JUST FOR YOUR

2700
01:46:26,760 --> 01:46:27,040
INFORMATION.

2701
01:46:27,040 --> 01:46:28,800
>> THANK YOU FOR YOUR SUPPORT.

2702
01:46:28,800 --> 01:46:30,120
I'M EXCITED TO HEAR ABOUT THE

2703
01:46:30,120 --> 01:46:30,960
PROGRAM.

2704
01:46:30,960 --> 01:46:33,080
THEY HAVE DONE AN INCREDIBLE JOB

2705
01:46:33,080 --> 01:46:34,520
IN MANAGING AND MOVING FORWARD

2706
01:46:34,520 --> 01:46:35,560
IN SPITE OF THE CHALLENGES OF

2707
01:46:35,560 --> 01:46:36,920
THE PANDEMIC OVER THE COUPLE

2708
01:46:36,920 --> 01:46:38,200
YEARS SO THERE'S REALLY A

2709
01:46:38,200 --> 01:46:39,080
COMMITTED TEAM WORKING TOGETHER

2710
01:46:39,080 --> 01:46:47,000
TO MAKE THAT PROJECT SUCCESSFUL.

2711
01:46:47,000 --> 01:46:47,360
>> DR. SHERMAN?

2712
01:46:47,360 --> 01:46:50,120
>> YES, THANK YOU FOR TALKING

2713
01:46:50,120 --> 01:46:50,880
ABOUT THIS.

2714
01:46:50,880 --> 01:46:53,800
I'M A BACK PAIN RESEARCHER AS

2715
01:46:53,800 --> 01:46:54,680
WELL.

2716
01:46:54,680 --> 01:46:56,560
HAVE DONE MUCH MORE ON THE CIH

2717
01:46:56,560 --> 01:46:59,120
END OF THINGS, AND NOW GETTING

2718
01:46:59,120 --> 01:47:00,360
INTO SOME IMPLEMENTATION

2719
01:47:00,360 --> 01:47:01,200
ASPECTS.

2720
01:47:01,200 --> 01:47:04,280
MY DREAM HAS ALWAYS BEEN TO

2721
01:47:04,280 --> 01:47:05,520
FIGURE OUT HOW TO TELL A BACK

2722
01:47:05,520 --> 01:47:07,840
PAIN PATIENT WHAT THEY SHOULD

2723
01:47:07,840 --> 01:47:10,840
TRY RIGHT AWAY THAT HAS A MUCH

2724
01:47:10,840 --> 01:47:12,920
GREATER CHANCE OF ACTUALLY

2725
01:47:12,920 --> 01:47:13,360
WORKING.

2726
01:47:13,360 --> 01:47:15,760
SO, I KNOW THAT THE PHENOTYPING

2727
01:47:15,760 --> 01:47:17,200
THAT YOU'RE DOING IN BACPAC IS

2728
01:47:17,200 --> 01:47:19,760
STILL MORE IN THE KIND OF

2729
01:47:19,760 --> 01:47:20,560
FORMATIVE AND MORE PRELIMINARY

2730
01:47:20,560 --> 01:47:22,840
STAGES BUT DO YOU SORT OF SEE A

2731
01:47:22,840 --> 01:47:25,960
VISION OF CARRYING THIS ALL THE

2732
01:47:25,960 --> 01:47:27,600
WAY THROUGH TO IMPLEMENTATION

2733
01:47:27,600 --> 01:47:31,480
AND MIGHT THAT BE ANOTHER AREA

2734
01:47:31,480 --> 01:47:35,960
WHERE NCCIH AND NIAMS COULD

2735
01:47:35,960 --> 01:47:39,040
PARTNER REALLY WELL?

2736
01:47:39,040 --> 01:47:39,760
>> ABSOLUTELY.

2737
01:47:39,760 --> 01:47:41,920
WE'RE SO FORTUNATE BACPAC IS

2738
01:47:41,920 --> 01:47:43,080
BEING SUPPORTED BY "HEAL" AND

2739
01:47:43,080 --> 01:47:44,320
THERE CONTINUES TO BE REALLY

2740
01:47:44,320 --> 01:47:46,800
STRONG SUPPORT OF THE "HEAL"

2741
01:47:46,800 --> 01:47:47,920
PROGRAM BECAUSE IT'S CLEAR THAT

2742
01:47:47,920 --> 01:47:50,080
"HEAL" IS GOING TO BE WELL

2743
01:47:50,080 --> 01:47:51,720
FUNDED IN THE YEARS AHEAD.

2744
01:47:51,720 --> 01:47:53,760
AND WE'RE ALREADY STARTING TO

2745
01:47:53,760 --> 01:47:55,640
THINK ABOUT WHAT BACPAC 2 WILL

2746
01:47:55,640 --> 01:47:56,680
LOOK LIKE.

2747
01:47:56,680 --> 01:47:58,280
WE WANT TO MAKE SURE WE'RE NOT

2748
01:47:58,280 --> 01:47:59,760
PREMATURE DEVELOPING PLANS.

2749
01:47:59,760 --> 01:48:03,360
WE WANT IT TO BE EVIDENCE-BASED

2750
01:48:03,360 --> 01:48:04,560
AND BUILD UPON NEW KNOWLEDGE

2751
01:48:04,560 --> 01:48:06,600
THAT COMES OUT OF BACPAC BUT

2752
01:48:06,600 --> 01:48:07,560
WE'RE EXCITED TO THINK ABOUT

2753
01:48:07,560 --> 01:48:08,200
WHAT'S NEXT.

2754
01:48:08,200 --> 01:48:09,800
WHAT CAN WE LEARN FROM THE

2755
01:48:09,800 --> 01:48:11,480
CURRENT PROGRAM?

2756
01:48:11,480 --> 01:48:13,240
AND WHAT WILL THAT SUGGEST WILL

2757
01:48:13,240 --> 01:48:16,960
THE BEST INVESTMENT ALSO MOVING

2758
01:48:16,960 --> 01:48:17,560
FORWARD?

2759
01:48:17,560 --> 01:48:19,680
CERTAINLY, YOU KNOW, THAT

2760
01:48:19,680 --> 01:48:22,960
CONCEPT OR REALLY CRIES OUT FOR

2761
01:48:22,960 --> 01:48:24,400
NCCIH INVOLVEMENT, SO LOOKING

2762
01:48:24,400 --> 01:48:26,040
FORWARD TO COLLABORATING WITH

2763
01:48:26,040 --> 01:48:29,760
ALL OF YOU IN A FUTURE VISION

2764
01:48:29,760 --> 01:48:32,840
FOR BACPAC.

2765
01:48:32,840 --> 01:48:43,200
>> GREAT. 

2766
01:48:43,200 --> 01:48:45,760
>> I HAVE A QUESTION ABOUT THE

2767
01:48:45,760 --> 01:48:48,560
AMP PROGRAM.

2768
01:48:48,560 --> 01:48:54,160
SO EXCITING TO BE ABLE TO

2769
01:48:54,160 --> 01:48:57,480
UTILIZE I GUESS MOSTLY BIOPSIES,

2770
01:48:57,480 --> 01:48:59,760
I IMAGINE, FROM HUMAN TISSUE TO

2771
01:48:59,760 --> 01:49:02,920
START LOOKING AT CELLULAR

2772
01:49:02,920 --> 01:49:05,080
MECHANISMS, AND WONDERING, USING

2773
01:49:05,080 --> 01:49:07,520
AN APPROACH LIKE THIS, COULD WE

2774
01:49:07,520 --> 01:49:09,520
EXTEND IT TO OTHER CONDITIONS?

2775
01:49:09,520 --> 01:49:12,360
I SUPPOSE THE LIMITATIONS, YOU

2776
01:49:12,360 --> 01:49:17,760
HAVE TO GET THE TISSUES, BUT

2777
01:49:17,760 --> 01:49:18,600
THERE ARE MINIMALLY INVASIVE

2778
01:49:18,600 --> 01:49:19,960
TYPES OF, FOR EXAMPLE, NEEDLE

2779
01:49:19,960 --> 01:49:21,760
BIOPSIES, FOR EXAMPLE, THAT CAN

2780
01:49:21,760 --> 01:49:22,960
BE DONE, FOR EXAMPLE, MUSCLE.

2781
01:49:22,960 --> 01:49:26,160
DO YOU SEE THIS TYPE OF APPROACH

2782
01:49:26,160 --> 01:49:28,440
EXTENDING TO OTHER

2783
01:49:28,440 --> 01:49:29,280
MUSCULOSKELETAL CONDITIONS?

2784
01:49:29,280 --> 01:49:32,600
>>  YEAH, YOU TOUCHED UPON A

2785
01:49:32,600 --> 01:49:34,040
REALLY CHALLENGING ASPECT OF THE

2786
01:49:34,040 --> 01:49:35,880
AMP PROGRAM WHICH WAS GETTING

2787
01:49:35,880 --> 01:49:37,920
ACCESS TO THE DISEASE TISSUES, A

2788
01:49:37,920 --> 01:49:38,760
CRITICAL GOAL.

2789
01:49:38,760 --> 01:49:42,120
I THINK AN ESSENTIAL FIRST STEP.

2790
01:49:42,120 --> 01:49:44,560
IT MADE THIS EFFORT CHALLENGING,

2791
01:49:44,560 --> 01:49:45,400
JUST DEVELOPING PROTOCOLS AND

2792
01:49:45,400 --> 01:49:47,240
REFINING THEM TO BE SUCCESSFUL,

2793
01:49:47,240 --> 01:49:51,640
NOT TO MENTION TRYING TO APPLY

2794
01:49:51,640 --> 01:49:53,040
CONSTANTLY EMERGING TECHNOLOGIES

2795
01:49:53,040 --> 01:49:54,360
TO STUDY THEM.

2796
01:49:54,360 --> 01:49:56,680
THERE'S SEVERAL WAYS LOOKING

2797
01:49:56,680 --> 01:49:59,320
FORWARD THIS COULD BE MORE

2798
01:49:59,320 --> 01:50:00,720
EASILY APPLIED ACROSS DISEASES

2799
01:50:00,720 --> 01:50:03,160
AND IN THE CLINIC EVEN.

2800
01:50:03,160 --> 01:50:04,680
SOME EFFORTS CURRENTLY IN MOVING

2801
01:50:04,680 --> 01:50:07,160
FORWARD WILL TRY TO LOOK AT THE

2802
01:50:07,160 --> 01:50:08,520
RELATIONSHIP BETWEEN FINDINGS IN

2803
01:50:08,520 --> 01:50:09,880
THE DISEASE TISSUE AND

2804
01:50:09,880 --> 01:50:12,560
PERIPHERAL BLOOD.

2805
01:50:12,560 --> 01:50:13,480
SO CAN WE IDENTIFY PERIPHERAL

2806
01:50:13,480 --> 01:50:14,920
BLOOD WHAT'S GOING ON IN THE

2807
01:50:14,920 --> 01:50:15,960
DISEASE TISSUE BASED ON WHAT

2808
01:50:15,960 --> 01:50:17,640
WE'RE LEARNING AS PART OF THE

2809
01:50:17,640 --> 01:50:21,360
AMP  PROGRAM?

2810
01:50:21,360 --> 01:50:22,760
ANOTHER PIECE WE'RE STARTING TO

2811
01:50:22,760 --> 01:50:24,640
ADDRESS AS PART OF A BRAND-NEW

2812
01:50:24,640 --> 01:50:27,560
EFFORT THAT'S JUST GETTING UNDER

2813
01:50:27,560 --> 01:50:31,600
WAY NOW CALLED THE AMP SYSTEMS

2814
01:50:31,600 --> 01:50:32,680
OF BIOLOGY INFORMATION APPROACH

2815
01:50:32,680 --> 01:50:36,880
WILL TRY TO TAKE ADVANTAGE OF

2816
01:50:36,880 --> 01:50:39,760
DATASETS BEING DEVELOPED ACROSS

2817
01:50:39,760 --> 01:50:40,600
MULTIPLE DISEASE, IMMUNE,

2818
01:50:40,600 --> 01:50:43,360
INFLAMMATORY, METABOLIC, TO TRY

2819
01:50:43,360 --> 01:50:45,640
TO UNDERSTAND COMMON PATHWAYS

2820
01:50:45,640 --> 01:50:48,600
ACROSS VERY DIVERSE CONDITIONS.

2821
01:50:48,600 --> 01:50:50,240
SO, THAT WILL FACILITATE AND

2822
01:50:50,240 --> 01:50:52,000
ENABLE US TO GO FROM DISCOVERIES

2823
01:50:52,000 --> 01:50:54,600
IN ONE DISEASE AND UNDERSTAND

2824
01:50:54,600 --> 01:50:55,240
IMPLICATIONS AND RAMIFICATIONS

2825
01:50:55,240 --> 01:50:56,480
FOR OTHER CONDITIONS.

2826
01:50:56,480 --> 01:50:59,120
SO, THINK IT'S A REALLY TIMELY

2827
01:50:59,120 --> 01:51:00,400
AND CRITICALLY IMPORTANT THING

2828
01:51:00,400 --> 01:51:02,080
TO UNDERTAKE NOW SO WE'RE REALLY

2829
01:51:02,080 --> 01:51:05,640
THINKING HARD ABOUT THAT.

2830
01:51:05,640 --> 01:51:07,640
BUT ABSOLUTELY, ONE CAN ENVISION

2831
01:51:07,640 --> 01:51:10,960
A RANGE OF OTHER RHEUMATIC

2832
01:51:10,960 --> 01:51:11,760
DISEASES, OSTEOARTHRITIS, THAT

2833
01:51:11,760 --> 01:51:12,880
WOULD BE A GREAT DISEASE TO

2834
01:51:12,880 --> 01:51:17,320
STUDY WITH AN AMP SORT OF

2835
01:51:17,320 --> 01:51:17,560
APPROACH.

2836
01:51:17,560 --> 01:51:19,200
SO WE'RE TRYING TO NOT GET IN

2837
01:51:19,200 --> 01:51:21,800
OVER OUR HEAD AND TO REALLY

2838
01:51:21,800 --> 01:51:24,000
FOCUS INITIALLY ON A CORE SET TO

2839
01:51:24,000 --> 01:51:26,200
LEARN HOW TO DO THIS, TO LEARN,

2840
01:51:26,200 --> 01:51:28,480
YOU KNOW, WHAT IS DISTINCT,

2841
01:51:28,480 --> 01:51:29,720
WHAT'S COMMON ACROSS DIFFERENT

2842
01:51:29,720 --> 01:51:31,040
DISEASE GROUPINGS, AND THEN TO

2843
01:51:31,040 --> 01:51:34,880
TRY TO LEVERAGE OUR SUCCESSES TO

2844
01:51:34,880 --> 01:51:36,160
SECURE FUNDING AND COMMITMENT TO

2845
01:51:36,160 --> 01:51:39,120
EXPAND THE GROUP OF CONDITIONS.

2846
01:51:39,120 --> 01:51:40,560
BUT IT'S ALMOST LIMITLESS, THE

2847
01:51:40,560 --> 01:51:41,880
TIMES OF CONDITIONS THAT COULD

2848
01:51:41,880 --> 01:51:43,440
BE EXAMINED IN THIS SORT OF

2849
01:51:43,440 --> 01:51:43,720
APPROACH.

2850
01:51:43,720 --> 01:51:46,160
I DON'T KNOW HOW MANY ARE

2851
01:51:46,160 --> 01:51:48,880
FAMILIAR WITH THE AMP PROGRAM

2852
01:51:48,880 --> 01:51:51,800
BUT THERE'S IMPRESSIVE WORK IN

2853
01:51:51,800 --> 01:51:54,880
NEUROLOGIC DISEASE, ALZHEIMER'S,

2854
01:51:54,880 --> 01:51:56,320
PARKINSON'S DISEASE GETTING

2855
01:51:56,320 --> 01:51:58,760
ACCESSION TO CENTRAL NERVOUS

2856
01:51:58,760 --> 01:51:59,400
SYSTEM TISSUE, METABOLIC

2857
01:51:59,400 --> 01:52:01,680
CONDITIONS, NOW HEART DISEASE.

2858
01:52:01,680 --> 01:52:05,120
IT'S REALLY AN EXCITING PROGRAM 

2859
01:52:05,120 --> 01:52:07,480
THAT WE CAN LEARN FROM ACROSS A

2860
01:52:07,480 --> 01:52:14,360
WIDE RANGE OF CONDITIONS MOVING

2861
01:52:14,360 --> 01:52:14,760
FORWARD.

2862
01:52:14,760 --> 01:52:16,320
>> IN SEEKING MYOFASCIAL PAIN,

2863
01:52:16,320 --> 01:52:22,840
WE STOPPED SHORT IN MYOFASCIAL,

2864
01:52:22,840 --> 01:52:24,680
YOU KNOW, RFA TO GOING AS FAR AS

2865
01:52:24,680 --> 01:52:25,800
BIOPSIES BUT THAT COULD BE

2866
01:52:25,800 --> 01:52:27,680
SOMETHING ELSE THAT COULD BE

2867
01:52:27,680 --> 01:52:28,920
LOOKED AT.

2868
01:52:28,920 --> 01:52:30,640
YOU KNOW, EVEN THOUGH -- IF

2869
01:52:30,640 --> 01:52:32,640
YOU'RE LOOKING FOR LONGITUDINAL

2870
01:52:32,640 --> 01:52:34,360
MEASUREMENTS, BIOPSIES ARE NOT

2871
01:52:34,360 --> 01:52:35,440
SO GREAT.

2872
01:52:35,440 --> 01:52:39,760
BUT IF YOU'RE LOOKING FOR

2873
01:52:39,760 --> 01:52:41,920
PHENOTYPING, YOU KNOW, IT MIGHT

2874
01:52:41,920 --> 01:52:45,200
BE THAT THAT COULD VERY WELL BE

2875
01:52:45,200 --> 01:52:48,080
USEFUL APPROACH.

2876
01:52:48,080 --> 01:52:50,560
IF DOING A SINGLE CELL RNAseq

2877
01:52:50,560 --> 01:52:52,200
ANALYSIS ON THE SAMPLE REVEALING

2878
01:52:52,200 --> 01:52:54,760
-- AND REALLY LOOKING AT ALL THE

2879
01:52:54,760 --> 01:52:55,840
DIFFERENT TYPES OF CELLS YOU CAN

2880
01:52:55,840 --> 01:52:57,880
FIND IN THE BIOPSY IS VERY, VERY

2881
01:52:57,880 --> 01:52:59,320
POWERFUL INDEED.

2882
01:52:59,320 --> 01:53:02,040
>> ONCE AGAIN, IF WE CAN

2883
01:53:02,040 --> 01:53:02,960
IDENTIFY PROXIES OR OTHER WAYS

2884
01:53:02,960 --> 01:53:05,440
TO, YOU KNOW, UNDERSTAND WHAT'S

2885
01:53:05,440 --> 01:53:08,600
GOING ON AT THE DISEASE TISSUE

2886
01:53:08,600 --> 01:53:10,800
LONGITUDINAL STUDIES BECOME MORE

2887
01:53:10,800 --> 01:53:12,360
FEASIBLE TOO.

2888
01:53:12,360 --> 01:53:21,520
>> RIGHT. 

2889
01:53:21,520 --> 01:53:22,880
ANY OTHER QUESTIONS?

2890
01:53:22,880 --> 01:53:24,880
PERHAPS WHAT WE SHOULD DO, IF

2891
01:53:24,880 --> 01:53:26,760
THERE ARE NO OTHER QUESTIONS

2892
01:53:26,760 --> 01:53:30,120
RIGHT NOW, WHAT I COULD DO IS

2893
01:53:30,120 --> 01:53:33,600
RUN THROUGH MY SHORT SORT OF

2894
01:53:33,600 --> 01:53:38,120
FOLLOW-UP TO DR. CRISWELL'S TALK

2895
01:53:38,120 --> 01:53:41,560
WHICH IS ABOUT RESTORATION OF

2896
01:53:41,560 --> 01:53:42,040
JOINT HEALTH.

2897
01:53:42,040 --> 01:53:43,480
I THINK DR. CRISWELL IS GOING TO

2898
01:53:43,480 --> 01:53:45,640
BE ABLE TO STAY, IS THAT

2899
01:53:45,640 --> 01:53:45,880
CORRECT?

2900
01:53:45,880 --> 01:53:47,160
>>  YES, I'M LOOKING FORWARD TO

2901
01:53:47,160 --> 01:53:48,320
HEARING YOUR THOUGHTS ABOUT

2902
01:53:48,320 --> 01:53:51,360
RE-JOIN AND WOULD BE HAPPY TO

2903
01:53:51,360 --> 01:53:52,080
STAY FOR THE DISCUSSION

2904
01:53:52,080 --> 01:53:53,840
FOLLOWING THAT AS WELL.

2905
01:53:53,840 --> 01:53:54,560
>> EXCELLENT.

2906
01:53:54,560 --> 01:53:58,360
I'M SURE -- YEAH, AND THEN WE

2907
01:53:58,360 --> 01:53:59,960
CAN GET BACK INTO QUESTIONS AND

2908
01:53:59,960 --> 01:54:02,040
INCORPORATE THEMES BECAUSE I

2909
01:54:02,040 --> 01:54:05,080
THINK WE'RE GOING TO FIND SOME

2910
01:54:05,080 --> 01:54:09,760
GOOD AREAS TO TALK ABOUT.

2911
01:54:09,760 --> 01:54:19,800
LET ME SHARE MY SCREEN. 

2912
01:54:19,800 --> 01:54:20,920
THERE WE GO.

2913
01:54:20,920 --> 01:54:21,160
OKAY.

2914
01:54:21,160 --> 01:54:23,360
CAN YOU ALL SEE THIS?

2915
01:54:23,360 --> 01:54:25,640
>>  YES.

2916
01:54:25,640 --> 01:54:27,760
>> OKAY. 

2917
01:54:27,760 --> 01:54:30,760
SO, THIS IS KIND OF A

2918
01:54:30,760 --> 01:54:33,720
PHILOSOPHICAL SORT OF DISCUSSION

2919
01:54:33,720 --> 01:54:35,920
ON WHAT I'M CALLING HERE WHOLE

2920
01:54:35,920 --> 01:54:37,760
JOINT HEALTH, RESTORING WHOLE

2921
01:54:37,760 --> 01:54:39,320
JOINT HEALTH, REALLY KIND OF A

2922
01:54:39,320 --> 01:54:41,000
FOLLOW-UP TO THE DISCUSSION THAT

2923
01:54:41,000 --> 01:54:43,560
WE'RE HAVING A LOT AT NCCIH, IN

2924
01:54:43,560 --> 01:54:48,800
TERMS OF WHOLE PERSON HEALTH.

2925
01:54:48,800 --> 01:54:52,360
ALL OF YOU HERE AT COUNCIL ARE

2926
01:54:52,360 --> 01:54:52,960
FAMILIAR OBVIOUSLY THAT WHOLE

2927
01:54:52,960 --> 01:54:54,520
PERSON HEALTH HAS BEEN EMERGING

2928
01:54:54,520 --> 01:54:57,440
THEME OUT OF OUR NEW STRATEGIC

2929
01:54:57,440 --> 01:54:57,680
PLAN.

2930
01:54:57,680 --> 01:54:59,400
REALLY DEFINING THIS, WHOLE

2931
01:54:59,400 --> 01:55:01,520
PERSON HEALTH, IS HELPING

2932
01:55:01,520 --> 01:55:04,920
INDIVIDUALS RESTORE THEIR HEALTH

2933
01:55:04,920 --> 01:55:12,520
IN MULTIPLE INTERCONNECTED 

2934
01:55:12,520 --> 01:55:14,560
DOMAINS, BEHAVIORAL, BIOLOGICAL,

2935
01:55:14,560 --> 01:55:15,440
SOCIAL, ENVIRONMENTAL.

2936
01:55:15,440 --> 01:55:16,440
WE HAVE DISCUSSION INCLUDING

2937
01:55:16,440 --> 01:55:19,080
HERE AT COUNCIL ABOUT WHY IS THE

2938
01:55:19,080 --> 01:55:22,360
WORD "PERSON" -- THERE'S A

2939
01:55:22,360 --> 01:55:25,080
CONCEPT OF WHOLE HEALTH, REALLY

2940
01:55:25,080 --> 01:55:27,600
TAKEN HOLD IN THE COMMUNITY THAT

2941
01:55:27,600 --> 01:55:30,080
REALLY ENCOMPASSES THIS.

2942
01:55:30,080 --> 01:55:31,480
YOU COULD DESCRIBE THIS, WHAT I

2943
01:55:31,480 --> 01:55:33,760
JUST TALKED ABOUT, IN TERMS OF

2944
01:55:33,760 --> 01:55:35,560
CALLING IT WHOLE HEALTH.

2945
01:55:35,560 --> 01:55:38,000
BUT THERE'S A REASON WHY WE

2946
01:55:38,000 --> 01:55:40,320
WANTED WORD "PERSON" IN HERE.

2947
01:55:40,320 --> 01:55:41,320
HERE IS WHY.

2948
01:55:41,320 --> 01:55:43,840
BECAUSE WHEN YOU'RE TALKING

2949
01:55:43,840 --> 01:55:45,680
ABOUT WHOLE PERSON HEALTH,

2950
01:55:45,680 --> 01:55:49,280
WITHIN THE BIOLOGICAL REALM, WE

2951
01:55:49,280 --> 01:55:51,240
HAVE MANY DIFFERENT SYSTEMS IN

2952
01:55:51,240 --> 01:55:54,600
THE BODY THAT TEND TO BE

2953
01:55:54,600 --> 01:55:55,320
STUDIED, NOT ALWAYS, BUT A LOT

2954
01:55:55,320 --> 01:55:59,880
OF TIMES KIND OF SEPARATE FROM

2955
01:55:59,880 --> 01:56:01,120
EACH OTHER.

2956
01:56:01,120 --> 01:56:04,000
CARDIOVASCULAR, METABOLIC, ET

2957
01:56:04,000 --> 01:56:04,480
CETERA.

2958
01:56:04,480 --> 01:56:07,240
AND MUSCULOSKELETAL.

2959
01:56:07,240 --> 01:56:08,960
AND THAT WE WANTED TO MAKE AN

2960
01:56:08,960 --> 01:56:13,200
EFFORT IN THIS WHOLE PERSON

2961
01:56:13,200 --> 01:56:16,840
HEALTH KIND OF THEME TO

2962
01:56:16,840 --> 01:56:18,560
INTEGRATE ACROSS VARIOUS

2963
01:56:18,560 --> 01:56:18,960
SYSTEMS.

2964
01:56:18,960 --> 01:56:20,760
FURTHERMORE WE WANT TO MAKE SURE

2965
01:56:20,760 --> 01:56:22,160
THIS INTEGRATION OCCURRED AT ALL

2966
01:56:22,160 --> 01:56:26,360
THE VARIOUS LEVELS I MENTIONED

2967
01:56:26,360 --> 01:56:26,880
BEFORE.

2968
01:56:26,880 --> 01:56:28,920
BIOLOGIC, BEHAVIORAL, SOCIAL,

2969
01:56:28,920 --> 01:56:29,240
ENVIRONMENTAL.

2970
01:56:29,240 --> 01:56:31,920
SO THAT THE HEALTH OF YOUR

2971
01:56:31,920 --> 01:56:33,760
LUNGS, FOR EXAMPLE, WOULD BE OF

2972
01:56:33,760 --> 01:56:35,840
COURSE AT THE TISSUE LEVEL,

2973
01:56:35,840 --> 01:56:38,360
HEALTHY LUNG TISSUE, ALSO AT THE

2974
01:56:38,360 --> 01:56:41,800
BEHAVIORAL LEVEL, FOR EXAMPLE,

2975
01:56:41,800 --> 01:56:45,240
YOU KNOW, BREATHING, FOR

2976
01:56:45,240 --> 01:56:46,760
EXAMPLE, INCORPORATED INTO AN

2977
01:56:46,760 --> 01:56:50,160
EXERCISE ROUTINE FOR EXAMPLE

2978
01:56:50,160 --> 01:56:50,360
YOGA.

2979
01:56:50,360 --> 01:56:51,240
SOCIAL AND ENVIRONMENTAL, ARE

2980
01:56:51,240 --> 01:56:54,200
YOU ABLE TO BREATHE CLEAN AIR?

2981
01:56:54,200 --> 01:56:57,600
WHAT ARE FACTORS THAT IMPACT

2982
01:56:57,600 --> 01:56:58,480
SOMEBODY'S RESPIRATORY HEALTH?

2983
01:56:58,480 --> 01:57:00,360
AS FAR AS MUSCULOSKELETAL

2984
01:57:00,360 --> 01:57:05,360
SYSTEM, SAME WOULD APPLY.

2985
01:57:05,360 --> 01:57:06,760
BIOLOGIC, STATUS OF JOINTS,

2986
01:57:06,760 --> 01:57:07,440
BONES, MUSCLE.

2987
01:57:07,440 --> 01:57:08,080
BEHAVIORAL, WHAT PHYSICAL

2988
01:57:08,080 --> 01:57:09,040
ACTIVITY DO YOU DO?

2989
01:57:09,040 --> 01:57:13,160
WHAT ARE SOCIAL AND

2990
01:57:13,160 --> 01:57:14,640
ENVIRONMENTAL FACTORS WHETHER OR

2991
01:57:14,640 --> 01:57:16,160
NOT YOU CAN EXERCISE OUTSIDE OR

2992
01:57:16,160 --> 01:57:17,360
SAFELY IN A GYM?

2993
01:57:17,360 --> 01:57:24,040
AND WHAT ARE FACTORS THAT IMPAIR

2994
01:57:24,040 --> 01:57:24,960
AND DON'T PROMOTE IT?

2995
01:57:24,960 --> 01:57:26,960
WE WANTED TO THINK ABOUT THE

2996
01:57:26,960 --> 01:57:29,240
IDEA THE WHOLE PERSON HEALTH

2997
01:57:29,240 --> 01:57:32,400
WITH WHAT WE CALL VERTICAL

2998
01:57:32,400 --> 01:57:34,720
INTEGRATION, INTEGRATING BODY

2999
01:57:34,720 --> 01:57:37,360
PARTS, AND THEN HORIZONTAL

3000
01:57:37,360 --> 01:57:40,520
INTEGRATION, WHICH IS THAT ALL

3001
01:57:40,520 --> 01:57:43,240
OF THIS, ALL OF THESE VARIOUS

3002
01:57:43,240 --> 01:57:45,680
FACTORS, ARE ON A CONTINUUM

3003
01:57:45,680 --> 01:57:47,760
BETWEEN HEALTH AND DISEASE, NOT

3004
01:57:47,760 --> 01:57:49,720
JUST SORT OF INEXORABLE

3005
01:57:49,720 --> 01:57:52,120
PROGRESSION TOWARDS DISEASE THAT

3006
01:57:52,120 --> 01:57:54,160
YOU CAN UNDERSTAND CERTAIN

3007
01:57:54,160 --> 01:57:55,280
CIRCUMSTANCES AND ESPECIALLY IF

3008
01:57:55,280 --> 01:57:57,240
SEEN AND TREATED EARLY, YOU CAN

3009
01:57:57,240 --> 01:57:59,960
RETURN, AT LEAST STOP THE

3010
01:57:59,960 --> 01:58:02,920
DISEASE PROGRESSION IF YOU'RE,

3011
01:58:02,920 --> 01:58:05,240
YOU KNOW, BUT ALSO PERHAPS

3012
01:58:05,240 --> 01:58:06,080
RESTORE FUNCTION, RESTORE

3013
01:58:06,080 --> 01:58:06,840
HEALTH.

3014
01:58:06,840 --> 01:58:09,200
SO WE WERE THINKING THAT THE

3015
01:58:09,200 --> 01:58:10,840
SAME MODEL COULD BE APPLIED TO

3016
01:58:10,840 --> 01:58:12,160
SOMETHING LIKE A JOINT, AND HOW

3017
01:58:12,160 --> 01:58:13,680
WOULD THAT WORK?

3018
01:58:13,680 --> 01:58:16,560
WELL, IF YOU THINK ABOUT THIS,

3019
01:58:16,560 --> 01:58:19,760
SIMILAR TO WHOLE BODY CONCEPT,

3020
01:58:19,760 --> 01:58:23,320
WHOLE PERSON HEALTH CONCEPT, THE

3021
01:58:23,320 --> 01:58:26,080
JOINT, AS DR. CRISWELL

3022
01:58:26,080 --> 01:58:26,800
MENTIONED, HAS MANY COMPONENTS,

3023
01:58:26,800 --> 01:58:27,040
RIGHT?

3024
01:58:27,040 --> 01:58:29,960
WE THINK ABOUT THE JOINT AS

3025
01:58:29,960 --> 01:58:33,800
BEING THIS KIND OF INNER PART OF

3026
01:58:33,800 --> 01:58:36,280
THE JOINT, CARTILAGE AND

3027
01:58:36,280 --> 01:58:37,640
ARTICULAR SURFACES BUT THERE'S

3028
01:58:37,640 --> 01:58:55,760
ALSO CAPSULE,  SYNOVIUM,

3029
01:58:55,760 --> 01:58:59,480
LIGAMENTS AND MUSCLES.

3030
01:58:59,480 --> 01:59:00,800
THE CONTINUUM, IF YOU THINK

3031
01:59:00,800 --> 01:59:03,760
ABOUT WHOLE JOINT HEALTH, WHAT

3032
01:59:03,760 --> 01:59:06,080
ARE FACTORS THAT COULD INFLUENCE

3033
01:59:06,080 --> 01:59:07,840
WHETHER OF WHETHER A PARTICULAR

3034
01:59:07,840 --> 01:59:14,800
JOINT MIGHT BE GETTING HEALTHIER

3035
01:59:14,800 --> 01:59:15,760
OR LESS HEALTHY.

3036
01:59:15,760 --> 01:59:22,680
AND PUTTING THIS IN CONTEXT OF

3037
01:59:22,680 --> 01:59:23,600
VARIOUS DOMAINS, INFLUENCED BY

3038
01:59:23,600 --> 01:59:27,320
OTHER TYPES OF FACTORS. 

3039
01:59:27,320 --> 01:59:29,360
WE STARTED THIS CONVERSATION

3040
01:59:29,360 --> 01:59:31,120
ABOUT THE JOINT INITIATIVE BY

3041
01:59:31,120 --> 01:59:34,760
STARTING TO THINK ABOUT WHAT ARE

3042
01:59:34,760 --> 01:59:37,120
VARIOUS COMPONENTS AND IS IT

3043
01:59:37,120 --> 01:59:39,720
POSSIBLE TO IDENTIFY COMPONENTS

3044
01:59:39,720 --> 01:59:40,840
THAT ARE ESSENTIALLY COMMON TO

3045
01:59:40,840 --> 01:59:42,160
ALL THE JOINTS.

3046
01:59:42,160 --> 01:59:43,680
THEY MIGHT NOT LOOK EXACTLY THE

3047
01:59:43,680 --> 01:59:46,840
SAME FROM ONE JOINT TO ANOTHER,

3048
01:59:46,840 --> 01:59:48,480
FOR EXAMPLE A TEMPOROMANDIBULAR

3049
01:59:48,480 --> 01:59:50,480
OR HIP JOINT OR KNEE JOINT.

3050
01:59:50,480 --> 01:59:52,760
THEY DON'T LOOK THE SAME, BUT

3051
01:59:52,760 --> 01:59:59,160
ALL OF THEM HAVE CERTAIN VARIOUS

3052
01:59:59,160 --> 02:00:00,040
COMPONENTS.

3053
02:00:00,040 --> 02:00:10,320
CARTILAGE, SYNOVIUM, JOINT

3054
02:00:10,320 --> 02:00:11,520
CAPSULES, LIGAMENTS, MUSCLES.

3055
02:00:11,520 --> 02:00:16,840
TO STUDY IN A WAY TRANSLATED

3056
02:00:16,840 --> 02:00:22,640
ACROSS JOINTS MIGHT BE USEFUL.

3057
02:00:22,640 --> 02:00:23,960
THIS LOOKS DIFFERENT, THE

3058
02:00:23,960 --> 02:00:25,360
TEMPOROMANDIBULAR, BUT YOU SEE

3059
02:00:25,360 --> 02:00:28,120
ALL THE COMPONENTS ARE THERE

3060
02:00:28,120 --> 02:00:32,360
WITH ONE ADDITIONAL, THE

3061
02:00:32,360 --> 02:00:33,240
INTRAARTICULAR DISK, FIBRO

3062
02:00:33,240 --> 02:00:34,640
CARTILAGE COMPONENT IN THE

3063
02:00:34,640 --> 02:00:34,960
MIDDLE.

3064
02:00:34,960 --> 02:00:38,240
IF THIS WERE A KNEE YOU WOULD

3065
02:00:38,240 --> 02:00:40,560
HAVE A MENISCUS.

3066
02:00:40,560 --> 02:00:43,360
BUT THE OTHER COMPONENTS WOULD

3067
02:00:43,360 --> 02:00:44,480
BE THERE.

3068
02:00:44,480 --> 02:00:47,800
AND SO THAT'S THE FIRST SORT OF

3069
02:00:47,800 --> 02:00:50,760
THOUGHT ABOUT TRYING TO CREATE A

3070
02:00:50,760 --> 02:00:52,920
STRUCTURE TO THINK ABOUT JOINTS

3071
02:00:52,920 --> 02:00:58,200
IN A WAY THAT WOULD BE A LITTLE 

3072
02:00:58,200 --> 02:00:59,880
BIT MORE UNIVERSAL OR GENERIC.

3073
02:00:59,880 --> 02:01:01,960
HOW COULD YOU THINK ABOUT A

3074
02:01:01,960 --> 02:01:03,440
JOINT UNIT?

3075
02:01:03,440 --> 02:01:05,640
THE SAME WAY WE STARTED TALKING

3076
02:01:05,640 --> 02:01:08,160
ABOUT MYOFASCIAL PAIN, TALKING

3077
02:01:08,160 --> 02:01:09,560
ABOUT THE MYOFASCIAL UNIT,

3078
02:01:09,560 --> 02:01:13,720
MEANING MUSCLES AND ASSOCIATED

3079
02:01:13,720 --> 02:01:15,600
CONNECTIVE TISSUE, PLUS LET'S

3080
02:01:15,600 --> 02:01:18,080
APPLY LYMPHATICS AND

3081
02:01:18,080 --> 02:01:18,360
INNERVATION.

3082
02:01:18,360 --> 02:01:19,080
SAME THING.

3083
02:01:19,080 --> 02:01:24,400
GENERIC JOINT UNIT WOULD INCLUDE

3084
02:01:24,400 --> 02:01:29,760
ARTICULAR AND PERIARTICULAR 

3085
02:01:29,760 --> 02:01:31,160
COMPONENTS, PLUS ASSOCIATED

3086
02:01:31,160 --> 02:01:36,440
INNERVATION AND VASCULAR AND

3087
02:01:36,440 --> 02:01:37,960
LYMPHATIC SUPPLY.

3088
02:01:37,960 --> 02:01:40,160
THE JOINT INITIATIVE THAT DR.

3089
02:01:40,160 --> 02:01:41,440
CRISWELL MENTIONED KIND OF WENT

3090
02:01:41,440 --> 02:01:45,200
AND STARTED WITH THESE BASIC

3091
02:01:45,200 --> 02:01:47,080
IDEAS, TO MAP THE DIFFERENT

3092
02:01:47,080 --> 02:01:49,480
TYPES AND WE DECIDED TO FOCUS ON

3093
02:01:49,480 --> 02:01:50,440
SENSORY NEURONS, RIGHT?

3094
02:01:50,440 --> 02:01:55,800
THIS WAS KIND OF, YOU KNOW,

3095
02:01:55,800 --> 02:02:01,280
INNERVATING ARTICULAR AND

3096
02:02:01,280 --> 02:02:02,440
PERIARTICULAR TISSUES, AUTONOMIC

3097
02:02:02,440 --> 02:02:03,000
SYMPATHETIC NERVE, SENSORY

3098
02:02:03,000 --> 02:02:05,760
NEURONS ARE IMPORTANT WHEN YOU

3099
02:02:05,760 --> 02:02:08,800
TALK ABOUT PAIN.

3100
02:02:08,800 --> 02:02:10,400
DOES THIS INNERVATION CHANGE

3101
02:02:10,400 --> 02:02:12,320
WITH AGE, PHYSICAL ACTIVITY,

3102
02:02:12,320 --> 02:02:13,680
WITH JOINT DEGENERATION,

3103
02:02:13,680 --> 02:02:14,360
ARTHRITIS?

3104
02:02:14,360 --> 02:02:16,960
HOW IS THIS INNERVATION

3105
02:02:16,960 --> 02:02:17,360
AFFECTED?

3106
02:02:17,360 --> 02:02:21,360
AND THIS WOULD UTILIZE ANIMAL

3107
02:02:21,360 --> 02:02:23,200
MODELS, HUMAN TISSUE OR BOTH.

3108
02:02:23,200 --> 02:02:25,840
AND HAVE A CONSORTIUM THAT WOULD

3109
02:02:25,840 --> 02:02:26,840
INTEGRATE DATA ACROSS VARIOUS

3110
02:02:26,840 --> 02:02:28,040
TYPES OF JOINTS.

3111
02:02:28,040 --> 02:02:33,760
WHAT WE WERE THINKING ABOUT, 

3112
02:02:33,760 --> 02:02:35,160
THIS RE-JOIN, CURRENT RE-JOIN

3113
02:02:35,160 --> 02:02:37,120
HEAL RFA FOR 2022 WOULD BE THE

3114
02:02:37,120 --> 02:02:38,640
IDEAL STARTING POINT FOR A

3115
02:02:38,640 --> 02:02:39,480
LONGER INITIATIVE ABOUT

3116
02:02:39,480 --> 02:02:40,720
RESTORING JOINT HEALTH AND HOW

3117
02:02:40,720 --> 02:02:45,760
WOULD THAT WORK?

3118
02:02:45,760 --> 02:02:48,920
WELL, THINK ABOUT STARTING WITH

3119
02:02:48,920 --> 02:02:51,640
JOINT PAIN, LOOKING AT ARTICULAR

3120
02:02:51,640 --> 02:02:54,600
TISSUES THEMSELVES, RIGHT?

3121
02:02:54,600 --> 02:02:55,560
CARTILAGE, RIGHT?

3122
02:02:55,560 --> 02:02:58,080
ASSOCIATED BONY TISSUES.

3123
02:02:58,080 --> 02:02:59,160
AND ALSO SYNOVIUM.

3124
02:02:59,160 --> 02:03:03,760
WHAT WE KNOW RIGHT NOW IN

3125
02:03:03,760 --> 02:03:05,760
LITERATURE, THERE'S ESTABLISHED

3126
02:03:05,760 --> 02:03:10,160
GOOD DATA SUGGESTING THAT IN THE

3127
02:03:10,160 --> 02:03:11,040
PRESENCE OF SPECIALLY

3128
02:03:11,040 --> 02:03:12,240
DEGENERATIVE JOINT DISEASES WE

3129
02:03:12,240 --> 02:03:14,120
HAVE CHANGES IN THESE TISSUES

3130
02:03:14,120 --> 02:03:16,080
WITH RESPECT TO INNERVATION AND

3131
02:03:16,080 --> 02:03:17,400
VASCULAR SUPPLY.

3132
02:03:17,400 --> 02:03:22,760
WE GET INGROWTH OF NERVES.

3133
02:03:22,760 --> 02:03:27,080
NORMALLY CARTILAGE DOES NOT HAVE

3134
02:03:27,080 --> 02:03:30,080
NOCICEPTORS AND IS AVASCULAR

3135
02:03:30,080 --> 02:03:34,920
BLOOD CAPPERS  CAPILLARIES.

3136
02:03:34,920 --> 02:03:37,960
YOU CAN GET INGROWTH OF

3137
02:03:37,960 --> 02:03:38,960
NOCICEPTORS AND SYMPATHETIC

3138
02:03:38,960 --> 02:03:52,280
NERVES INTO THE CARTILAGE AND

3139
02:03:52,280 --> 02:04:01,440
SUBCONDRIA BONE.

3140
02:04:01,440 --> 02:04:03,360
SAME WITH SYNOVIUM, NOCICEPTOR

3141
02:04:03,360 --> 02:04:04,240
SENSITIZATION, MECHANISMS THAT

3142
02:04:04,240 --> 02:04:08,560
ARE KNOWN, THAT ARE ESTABLISHED.

3143
02:04:08,560 --> 02:04:10,720
WHAT WE WOULD LIKE TO DO HERE IS

3144
02:04:10,720 --> 02:04:12,880
EXPAND OUR VIEW OF JOINT PAIN

3145
02:04:12,880 --> 02:04:16,280
AND START TO THINK ABOUT WHAT

3146
02:04:16,280 --> 02:04:19,960
OTHER TYPES OF MECHANISMS IN

3147
02:04:19,960 --> 02:04:20,960
PERIARTICULAR TISSUES MAY ALSO

3148
02:04:20,960 --> 02:04:22,280
PERHAPS CONTRIBUTE TO JOINT

3149
02:04:22,280 --> 02:04:23,800
PAIN.

3150
02:04:23,800 --> 02:04:25,240
IF YOUR KNEE HURTS, FOR EXAMPLE,

3151
02:04:25,240 --> 02:04:27,080
WELL WE DON'T REALLY KNOW IF THE

3152
02:04:27,080 --> 02:04:30,560
PAIN IS ACTUALLY COMING FROM THE

3153
02:04:30,560 --> 02:04:32,680
ARTICULAR TISSUES THEMSELVES,

3154
02:04:32,680 --> 02:04:40,240
I.E. CARTILAGE AND SYNOVIUM OR

3155
02:04:40,240 --> 02:04:41,640
COMING FROM TISSUES AROUND THE

3156
02:04:41,640 --> 02:04:41,960
JOINT?

3157
02:04:41,960 --> 02:04:44,160
A PERSON WOULD NOT KNOW THIS,

3158
02:04:44,160 --> 02:04:44,720
RIGHT?

3159
02:04:44,720 --> 02:04:46,120
MY KNEE HURTS WAY ONE OR

3160
02:04:46,120 --> 02:04:49,840
ANOTHER, BUT IT'S POSSIBLE YOU

3161
02:04:49,840 --> 02:04:50,320
COULD HAVE NOCICEPTOR

3162
02:04:50,320 --> 02:04:51,520
SENSITIZATION FOR EXAMPLAR IN

3163
02:04:51,520 --> 02:04:56,960
THE JOINT  CAPSULES OR LIGAMENTS

3164
02:04:56,960 --> 02:04:59,160
THAT WOULD FEEL LIKE JOINT PAIN.

3165
02:04:59,160 --> 02:05:01,720
WE DON'T HAVE KNOWLEDGE BECAUSE

3166
02:05:01,720 --> 02:05:03,840
WE HAVEN'T STUDIED THIS AS MUCH.

3167
02:05:03,840 --> 02:05:05,480
WE HAVEN'T STUDY MYOFASCIAL PAIN

3168
02:05:05,480 --> 02:05:07,000
AND PRESENCE OF MYOFASCIAL

3169
02:05:07,000 --> 02:05:08,960
TRIGGER POINTS, POSSIBLY NEAR

3170
02:05:08,960 --> 02:05:12,320
THE INSERTION OF THE MUSCLES

3171
02:05:12,320 --> 02:05:15,920
INTO THE JOINTS, INTO THE

3172
02:05:15,920 --> 02:05:17,360
CAPSULES AND LIGAMENTS BECAUSE

3173
02:05:17,360 --> 02:05:20,080
THESE CONNECTIVE TISSUES, THEY

3174
02:05:20,080 --> 02:05:23,360
ARE DRAWN HERE IN SEPARATE

3175
02:05:23,360 --> 02:05:25,760
COLORS BUT ONE IMPOSE INTO THE

3176
02:05:25,760 --> 02:05:25,960
OTHER.

3177
02:05:25,960 --> 02:05:27,320
THERE'S NOT A LINE THAT SAYS,

3178
02:05:27,320 --> 02:05:29,920
OKAY, HERE IS WHERE THE FASCIA

3179
02:05:29,920 --> 02:05:31,680
STARTS, STOPS, WHERE THE

3180
02:05:31,680 --> 02:05:33,040
LIGAMENT STARTS.

3181
02:05:33,040 --> 02:05:36,920
IT ALL RUNS INTO ITSELF.

3182
02:05:36,920 --> 02:05:40,080
SO, WE HAVE A SEPARATE

3183
02:05:40,080 --> 02:05:42,560
INITIATIVE LOOKING AT DEVELOPING

3184
02:05:42,560 --> 02:05:45,040
MARKERS FOR MYOFASCIAL PAIN, AND

3185
02:05:45,040 --> 02:05:48,600
WE THINK THIS WOULD BE HELP

3186
02:05:48,600 --> 02:05:50,400
UNDERSTAND NOT ONLY MYOFASCIAL

3187
02:05:50,400 --> 02:05:51,920
TISSUES BUT ALSO JOINTS.

3188
02:05:51,920 --> 02:05:55,040
SO, THE IDEA THAT IF WE COULD

3189
02:05:55,040 --> 02:05:56,920
UNDERSTAND BETTER HOW TO

3190
02:05:56,920 --> 02:05:59,200
DIAGNOSE AND TREAT MYOFASCIAL

3191
02:05:59,200 --> 02:06:01,000
TRIGGER POINTS IT MY VERY WELL

3192
02:06:01,000 --> 02:06:03,400
BE HELPFUL IN THE MANAGEMENT OF

3193
02:06:03,400 --> 02:06:04,920
JOINT PAIN.

3194
02:06:04,920 --> 02:06:05,120
OKAY.

3195
02:06:05,120 --> 02:06:07,960
SO, NOW HERE WE'VE LOOKED AT --

3196
02:06:07,960 --> 02:06:09,160
THERE MAY BE ANOTHER REASON WHY

3197
02:06:09,160 --> 02:06:11,560
WE WANT TO LOOK AT THIS.

3198
02:06:11,560 --> 02:06:16,960
THE REASON IS THAT THERE MAY BE

3199
02:06:16,960 --> 02:06:18,160
A RELATIONSHIP, TEMPORALLY,

3200
02:06:18,160 --> 02:06:19,920
BETWEEN SUPPORTING STRUCTURES

3201
02:06:19,920 --> 02:06:22,160
AND ARTICULAR SURFACES.

3202
02:06:22,160 --> 02:06:23,880
IMAGINE THAT YOU HAVE A JOINT

3203
02:06:23,880 --> 02:06:26,720
OVER HERE ON THE LEFT WHERE

3204
02:06:26,720 --> 02:06:29,440
SOMEBODY HAS AN IMBALANCE IN THE

3205
02:06:29,440 --> 02:06:32,840
MUSCLE ACTIVITY, ON ONE SIDE

3206
02:06:32,840 --> 02:06:34,720
MUSCLES ARE CONTRACTED, PERHAPS

3207
02:06:34,720 --> 02:06:36,680
UNDERUSED, PERHAPS A PERSON IS

3208
02:06:36,680 --> 02:06:37,840
FAVORING ONE SIDE AND THE JOINT

3209
02:06:37,840 --> 02:06:39,240
IS GOING OUT OF ALIGNMENT

3210
02:06:39,240 --> 02:06:43,200
BECAUSE FUNCTION OF THE MUSCLES

3211
02:06:43,200 --> 02:06:44,960
HAS BECOME UNBALANCED.

3212
02:06:44,960 --> 02:06:46,160
SIMILARLY CONNECTIVE TISSUES ON

3213
02:06:46,160 --> 02:06:48,680
ONE SIDE HAVE OF MAY HAVE GOTTEN

3214
02:06:48,680 --> 02:06:51,160
THICKER AND STUFF SO THERE'S NOT

3215
02:06:51,160 --> 02:06:53,360
AN OPTIMUM MOBILITY OF THESE

3216
02:06:53,360 --> 02:06:54,520
TISSUES WHICH FURTHER IMBALANCES

3217
02:06:54,520 --> 02:06:55,440
JOINT MECHANICS.

3218
02:06:55,440 --> 02:06:59,320
SO IF YOU HAVE A COMBINATION OF

3219
02:06:59,320 --> 02:07:01,840
WEAK MUSCLES, STIFF CONNECTIVE

3220
02:07:01,840 --> 02:07:03,800
TISSUES AND MISALIGNED JOINT,

3221
02:07:03,800 --> 02:07:06,560
THIS MALFUNCTION IN DEGENERATION

3222
02:07:06,560 --> 02:07:07,720
OF SUPPORTED STRUCTURES COULD

3223
02:07:07,720 --> 02:07:09,960
PREDISPOSE AND LEAD TO DAMAGE TO

3224
02:07:09,960 --> 02:07:11,200
THE ARTICULAR SURFACES.

3225
02:07:11,200 --> 02:07:12,600
THIS JUST MAKES COMMON SENSE,

3226
02:07:12,600 --> 02:07:12,800
RIGHT?

3227
02:07:12,800 --> 02:07:15,960
IF YOU HAVE A JOINT THAT IS NO

3228
02:07:15,960 --> 02:07:18,080
LONGER WELL ALIGNED YOU MAY HAVE

3229
02:07:18,080 --> 02:07:20,240
INCREASED WEAR ON ONE SIDE OF

3230
02:07:20,240 --> 02:07:30,360
THE ARTICULAR SURFACE, THE

3231
02:07:30,360 --> 02:07:31,240
CARTILAGE, AND INCREASED

3232
02:07:31,240 --> 02:07:31,600
(INDISCERNIBLE).

3233
02:07:31,600 --> 02:07:32,880
IT COULD BE PERSON UNDERSTANDING

3234
02:07:32,880 --> 02:07:34,320
WHY THE JOINT BECOMES

3235
02:07:34,320 --> 02:07:36,160
DEGENERATED BUT MOST IMPORTANTLY

3236
02:07:36,160 --> 02:07:38,920
ALSO COULD BE PREVENTED, IF IT

3237
02:07:38,920 --> 02:07:40,560
WAS ADDRESSED.

3238
02:07:40,560 --> 02:07:45,040
SO, THE IDEA HERE WOULD BE THAT

3239
02:07:45,040 --> 02:07:47,440
THESE -- IF YOU COULD DEVELOP A

3240
02:07:47,440 --> 02:07:59,600
WHOLE PERSON JO OF -- VIEW OF 

3241
02:07:59,600 --> 02:08:01,360
JOINT PAIN IT COULD INCLUDE

3242
02:08:01,360 --> 02:08:04,960
OTHER FACTORS THAT I MENTIONED

3243
02:08:04,960 --> 02:08:05,960
EARLIER, ENVIRONMENTAL,

3244
02:08:05,960 --> 02:08:07,480
PSYCHOLOGICAL FACTORS, OBESITY,

3245
02:08:07,480 --> 02:08:09,520
POSTURE HABITS, MOVEMENT

3246
02:08:09,520 --> 02:08:11,640
PATTERNS, STRESS, MUSCLE

3247
02:08:11,640 --> 02:08:12,960
TENSION, ALL THESE THINGS MAY

3248
02:08:12,960 --> 02:08:14,840
HAVE EFFECT ON THE FUNCTIONING

3249
02:08:14,840 --> 02:08:17,360
OF THE WHOLE JOINT UNIT.

3250
02:08:17,360 --> 02:08:20,120
AND SO THE IDEA WE HAVE KIND OF

3251
02:08:20,120 --> 02:08:21,960
A VICIOUS CIRCLE SETUP WHERE THE

3252
02:08:21,960 --> 02:08:28,400
MORE PAIN YOU HAVE, THE MORE

3253
02:08:28,400 --> 02:08:35,520
DIFFICULT TO EXERCISE, POSTURE

3254
02:08:35,520 --> 02:08:36,720
MAY FURTHER DETERIORATE, MORE

3255
02:08:36,720 --> 02:08:38,360
TIME SETTING, WEIGHT GOES UP, WE

3256
02:08:38,360 --> 02:08:41,320
KNOW A LOT OF THESE SITUATIONS,

3257
02:08:41,320 --> 02:08:45,520
CONDITIONS, ARE CO-OCCURRING.

3258
02:08:45,520 --> 02:08:48,760
PATIENTS WHO HAVE PROBLEMS, POOR

3259
02:08:48,760 --> 02:08:50,000
DIET, SEDENTARY LIFESTYLE, OFTEN

3260
02:08:50,000 --> 02:08:52,080
HAVE SOMETIMES DEPRESSION, A LOT

3261
02:08:52,080 --> 02:08:53,440
HAVE CHRONIC PAIN, A LOT OF

3262
02:08:53,440 --> 02:08:58,960
CHRONIC PAIN IS CHRONIC JOINT

3263
02:08:58,960 --> 02:09:05,080
PAIN.  SO THINKING ABOUT THE

3264
02:09:05,080 --> 02:09:05,680
CONTINUUM BETWEEN HEALTH AND

3265
02:09:05,680 --> 02:09:07,960
DISEASE WHERE YOU MIGHT BE ABLE

3266
02:09:07,960 --> 02:09:12,560
TO  INTERVENE AND PERHAPS

3267
02:09:12,560 --> 02:09:20,280
PREVENT OR RETAIN BY LOSING UP

3268
02:09:20,280 --> 02:09:22,160
TISSUES AND ADHESIONS, MAYBE

3269
02:09:22,160 --> 02:09:22,800
LOOSENING THOSE UP,

3270
02:09:22,800 --> 02:09:26,000
STRENGTHENING MUSCLES THAT HAVE

3271
02:09:26,000 --> 02:09:27,560
BECOME WEAK AND ENGAGING,

3272
02:09:27,560 --> 02:09:28,720
CORRECTING THE POSTURE, ALL OF

3273
02:09:28,720 --> 02:09:32,680
THESE THINGS MAY HAVE AN EFFECT

3274
02:09:32,680 --> 02:09:35,080
ON THE DEVELOPMENT AND PERHAPS

3275
02:09:35,080 --> 02:09:37,720
REVERSAL OF THE JOINT PATHOLOGY.

3276
02:09:37,720 --> 02:09:41,080
SO, OPPORTUNITIES, RIGHT, FOR

3277
02:09:41,080 --> 02:09:43,400
PREVENTION AND RESTORATION,

3278
02:09:43,400 --> 02:09:44,280
INCLUDING NUTRITIONAL,

3279
02:09:44,280 --> 02:09:45,480
PSYCHOLOGICAL, PHYSICAL, BY

3280
02:09:45,480 --> 02:09:47,760
IMPROVING ALL OF THESE VICIOUS

3281
02:09:47,760 --> 02:09:52,040
CIRCLES, START GOING BACK IN THE

3282
02:09:52,040 --> 02:09:54,640
OTHER DIRECTION, IMPROVING SORT

3283
02:09:54,640 --> 02:09:56,520
OF, FOR EXAMPLE, LOCAL MANUAL

3284
02:09:56,520 --> 02:09:57,520
THERAPIES, FOR EXAMPLE, APPLIED

3285
02:09:57,520 --> 02:10:00,920
TO CONNECTIVE TISSUE TO LOOSEN

3286
02:10:00,920 --> 02:10:02,200
THEM, MOVEMENT THERAPIES,

3287
02:10:02,200 --> 02:10:03,280
PHYSICAL THERAPY TO STRENGTHEN

3288
02:10:03,280 --> 02:10:10,040
MUSCLES WHERE THEY NEED TO BE,

3289
02:10:10,040 --> 02:10:12,560
AND THEN OF COURSE IMPROVING,

3290
02:10:12,560 --> 02:10:17,360
FOR EXAMPLE, ACCESS TO ALL OF

3291
02:10:17,360 --> 02:10:19,880
THESE TYPES OF THERAPIES AND,

3292
02:10:19,880 --> 02:10:23,480
FOR EXAMPLE, EXERCISE, AND

3293
02:10:23,480 --> 02:10:25,240
IMPROVING THAT FROM THE SOCIAL

3294
02:10:25,240 --> 02:10:25,680
STANDPOINT.

3295
02:10:25,680 --> 02:10:31,160
SO YOU CAN SEE ADDRESSING THESE

3296
02:10:31,160 --> 02:10:33,040
VARIOUS DIFFERENT COMPONENTS OF

3297
02:10:33,040 --> 02:10:36,520
JOINT PAIN FROM THE FULL PERSON

3298
02:10:36,520 --> 02:10:37,840
DOWN TO THE CARTILAGE CAN HELP

3299
02:10:37,840 --> 02:10:41,200
US TO UNDERSTAND BETTER HOW WE

3300
02:10:41,200 --> 02:10:43,960
CAN PREVENT PROBLEMS AND

3301
02:10:43,960 --> 02:10:46,680
EVENTUALLY GOING BACK TO THE

3302
02:10:46,680 --> 02:10:48,520
ORIGINAL AIM OF RE-JOIN, WHICH

3303
02:10:48,520 --> 02:10:51,040
IS TO MAP SENSORY INNERVATION

3304
02:10:51,040 --> 02:10:52,640
AND OF COURSE ALSO SYMPATHETIC

3305
02:10:52,640 --> 02:10:55,160
IS VERY IMPORTANT I THINK AS

3306
02:10:55,160 --> 02:10:58,360
WELL, TO PERHAPS UNDERSTAND

3307
02:10:58,360 --> 02:11:01,120
WHETHER SOME OF THIS,

3308
02:11:01,120 --> 02:11:02,200
NEOVASCULARIZATION AND INGROWTH

3309
02:11:02,200 --> 02:11:04,600
IN CARTILAGE MIGHT BE

3310
02:11:04,600 --> 02:11:05,160
REVERSIBLE.

3311
02:11:05,160 --> 02:11:07,160
AND SO I THINK THAT THE

3312
02:11:07,160 --> 02:11:08,880
IMPORTANT THING WILL BE TO

3313
02:11:08,880 --> 02:11:12,800
FOLLOW UP ON THIS INITIAL

3314
02:11:12,800 --> 02:11:13,480
RE-JOIN PROGRAM, WITH

3315
02:11:13,480 --> 02:11:15,800
INTERVENTIONS THAT MAY BE

3316
02:11:15,800 --> 02:11:18,160
APPLIED TO THIS, AT VARIOUS

3317
02:11:18,160 --> 02:11:22,200
STAGES OF PROGRESSION ALONG THIS

3318
02:11:22,200 --> 02:11:24,960
CONTINUUM, TO SEE WHETHER IT'S

3319
02:11:24,960 --> 02:11:26,760
POSSIBLE TO REALLY RESTORE THE

3320
02:11:26,760 --> 02:11:29,200
HEALTH OF THE JOINT.

3321
02:11:29,200 --> 02:11:32,480
SO, I HOPE I HAVE CONVINCED YOU

3322
02:11:32,480 --> 02:11:34,960
THIS IS AN AREA WHERE THE

3323
02:11:34,960 --> 02:11:36,680
CONCEPT OF WHOLE PERSONAL HEALTH

3324
02:11:36,680 --> 02:11:38,800
CAN BE PRETTY MUCH COPIED AND

3325
02:11:38,800 --> 02:11:41,360
PASTED, RIGHT?

3326
02:11:41,360 --> 02:11:42,560
ONTO THE CONCEPT OF WHOLE JOINT

3327
02:11:42,560 --> 02:11:43,080
HEALTH.

3328
02:11:43,080 --> 02:11:44,920
YOU HAVE THE WHOLE INTEGRATION

3329
02:11:44,920 --> 02:11:48,440
OF ALL OF VARIOUS PIECES AND YOU

3330
02:11:48,440 --> 02:11:51,960
HAVE THE SORT OF TIME COMPONENT,

3331
02:11:51,960 --> 02:11:58,440
HEALTH TO DISEASE, THE BACK AND 

3332
02:11:58,440 --> 02:11:59,360
FORTH CONTINUUM.

3333
02:11:59,360 --> 02:12:00,600
IF THIS CAN BE DONE FOR JOINTS

3334
02:12:00,600 --> 02:12:02,560
IT CAN BE DONE FOR OTHER THINGS.

3335
02:12:02,560 --> 02:12:05,360
I LOVE THE IDEA OF WHOLE

3336
02:12:05,360 --> 02:12:06,720
DIGESTIVE HEALTH.

3337
02:12:06,720 --> 02:12:08,560
THE DIGESTIVE SYSTEM IS NOT

3338
02:12:08,560 --> 02:12:09,560
ISOLATED IN THE BODY.

3339
02:12:09,560 --> 02:12:12,160
IT'S NOT JUST A TUBE.

3340
02:12:12,160 --> 02:12:15,680
IT'S SURROUNDED BY ORGANS BY

3341
02:12:15,680 --> 02:12:17,120
MUSCLES, THE DIAPHRAGM, LUNGS

3342
02:12:17,120 --> 02:12:18,160
THAT BREATHE.

3343
02:12:18,160 --> 02:12:19,600
YOU KNOW, THERE'S ALL KINDS OF

3344
02:12:19,600 --> 02:12:26,720
ACTIVITY GOING ON THAT COULD 

3345
02:12:26,720 --> 02:12:29,120
INFLUENCE DIGESTION, PLUS DIET,

3346
02:12:29,120 --> 02:12:30,200
MICROBIOME, OUTSIDE WORLD, THE

3347
02:12:30,200 --> 02:12:31,080
EXERCISE WE DO.

3348
02:12:31,080 --> 02:12:34,040
THE IDEA THIS CONCEPT OF WHOLE

3349
02:12:34,040 --> 02:12:37,360
PERSON HEALTH CAN REALLY BE

3350
02:12:37,360 --> 02:12:39,640
APPLIED AT A SYSTEMS LEVEL AND I

3351
02:12:39,640 --> 02:12:43,680
THINK THAT JUST SORT OF THINKING

3352
02:12:43,680 --> 02:12:47,960
ABOUT IT, AT ALL THE DIFFERENT

3353
02:12:47,960 --> 02:12:49,160
COMPONENTS IN TERMS OF WHAT PUTS

3354
02:12:49,160 --> 02:12:52,960
THE WHOLE PERSON TOGETHER AND

3355
02:12:52,960 --> 02:12:54,840
HOW DOES IT INTERACT WITH THE

3356
02:12:54,840 --> 02:12:58,040
OUTSIDE WORLD AND MOVE BACK AND

3357
02:12:58,040 --> 02:12:59,760
FORTH IN HEALTHY DISEASE IS AN

3358
02:12:59,760 --> 02:13:02,320
AREA WE CAN -- IT'S LIKE A

3359
02:13:02,320 --> 02:13:05,760
BLUEPRINT TO LOOK AT A VARIETY

3360
02:13:05,760 --> 02:13:08,560
OF DIFFERENT SITUATIONS.

3361
02:13:08,560 --> 02:13:10,080
SO I'LL STOP HERE.

3362
02:13:10,080 --> 02:13:18,080
I LOOK FORWARD TO HEARING WHAT

3363
02:13:18,080 --> 02:13:18,440
PEOPLE THINK.

3364
02:13:18,440 --> 02:13:21,040
>>  QUESTIONS, COMMENTS FROM

3365
02:13:21,040 --> 02:13:22,560
COUNCIL?

3366
02:13:22,560 --> 02:13:25,400
>> IF I CAN JUST SAY THANK YOU

3367
02:13:25,400 --> 02:13:26,200
SO MUCH.

3368
02:13:26,200 --> 02:13:29,360
IT STRUCK ME SO MUCH WITH YOUR

3369
02:13:29,360 --> 02:13:30,240
PRESENTATION, THINKING ABOUT

3370
02:13:30,240 --> 02:13:34,800
THIS EFFORT, IT REALLY NICELY

3371
02:13:34,800 --> 02:13:35,560
ILLUSTRATES THE TREMENDOUS

3372
02:13:35,560 --> 02:13:39,520
OPPORTUNITY AT THE NIH WITH THE

3373
02:13:39,520 --> 02:13:41,800
DIFFERENT INSTITUTES AND AREAS

3374
02:13:41,800 --> 02:13:43,760
OF EXPERTISE.

3375
02:13:43,760 --> 02:13:46,200
THIS RE-JOIN CONCEPT AND THE

3376
02:13:46,200 --> 02:13:49,160
EXTENDED PROPOSAL, YOU KNOW,

3377
02:13:49,160 --> 02:13:51,040
OBVIOUSLY VERY IMPORTANTLY

3378
02:13:51,040 --> 02:13:52,360
REFLECTS PERSPECTIVE THAT NCCIH

3379
02:13:52,360 --> 02:14:02,520
BRINGS TO THIS AND THE KIND OF 

3380
02:14:02,520 --> 02:14:03,600
NEUROLOGIC ASPECT REFLECTS

3381
02:14:03,600 --> 02:14:06,760
EXPERTISE, AND NIAMS

3382
02:14:06,760 --> 02:14:07,560
INVESTIGATORS CONTRIBUTED TO

3383
02:14:07,560 --> 02:14:10,120
THINKING ABOUT THIS, A GREAT

3384
02:14:10,120 --> 02:14:11,640
COLLABORATION ACROSS I.C.s TO

3385
02:14:11,640 --> 02:14:12,960
CREATE SOMETHING THAT WOULDN'T

3386
02:14:12,960 --> 02:14:13,880
HAVE HAPPENED IN ANY OF THE

3387
02:14:13,880 --> 02:14:15,800
I.C.s ON THEIR OWN.

3388
02:14:15,800 --> 02:14:21,280
>> I SAID IT PERFECTLY, LINDSEY.

3389
02:14:21,280 --> 02:14:29,760
I HAVE TO SAY IT IS YOU,

3390
02:14:29,760 --> 02:14:30,840
LINDSEY, WHO INITIATED THIS,

3391
02:14:30,840 --> 02:14:33,280
WORKING TOGETHER TO LOOK AT

3392
02:14:33,280 --> 02:14:33,520
JOINTS.

3393
02:14:33,520 --> 02:14:34,280
AND THEN WE STARTED TALKING

3394
02:14:34,280 --> 02:14:36,160
ABOUT JOINT HEALTH.

3395
02:14:36,160 --> 02:14:37,440
THEN WE STARTED TALKING ABOUT

3396
02:14:37,440 --> 02:14:38,360
SENSORY NERVES.

3397
02:14:38,360 --> 02:14:40,320
AND THEN ALL OF A SUDDEN THERE

3398
02:14:40,320 --> 02:14:42,800
WAS THIS CONCEPT THAT SORT OF

3399
02:14:42,800 --> 02:14:44,080
CAME TOGETHER.

3400
02:14:44,080 --> 02:14:47,560
SO I THINK THIS IS REALLY

3401
02:14:47,560 --> 02:14:50,080
SPEAKING VOLUMES HOW TO ALL THE

3402
02:14:50,080 --> 02:14:52,920
DIFFERENT INSTITUTES CAN COME

3403
02:14:52,920 --> 02:14:58,120
TOGETHER AND DO SOMETHING WE

3404
02:14:58,120 --> 02:15:01,640
HAVEN'T DONE BEFORE.

3405
02:15:01,640 --> 02:15:03,720
>> DR. EVANS AND DR. SHERMAN.

3406
02:15:03,720 --> 02:15:04,960
>> THANK YOU FOR THE WONDERFUL

3407
02:15:04,960 --> 02:15:05,160
TALK.

3408
02:15:05,160 --> 02:15:05,960
I LOVE IT.

3409
02:15:05,960 --> 02:15:08,960
AT FIRST WHEN YOU WERE STARTING

3410
02:15:08,960 --> 02:15:10,960
OUT, IT WAS JUST FOCUSED ON

3411
02:15:10,960 --> 02:15:12,080
INDIVIDUAL ELEMENTS OF THE

3412
02:15:12,080 --> 02:15:14,520
JOINT, I WAS ON BOARD WITH

3413
02:15:14,520 --> 02:15:15,520
COMMONALITY OF LOOKING AT JOINTS

3414
02:15:15,520 --> 02:15:19,120
BUT THEN WHEN YOU PUT IN THE 

3415
02:15:19,120 --> 02:15:23,160
REST OF THIS,  PSYCHOSOCIAL I

3416
02:15:23,160 --> 02:15:25,640
GOT EXCITED.

3417
02:15:25,640 --> 02:15:29,160
THIS IS SOMETHING, THE

3418
02:15:29,160 --> 02:15:30,800
WHOLE-PERSON, WHOLE-SYSTEMS

3419
02:15:30,800 --> 02:15:31,920
APPROACH IS SOMETHING THAT'S

3420
02:15:31,920 --> 02:15:33,480
IMPORTANT FOR ALL CHRONIC HEALTH

3421
02:15:33,480 --> 02:15:33,760
CONDITIONS.

3422
02:15:33,760 --> 02:15:35,160
VERY EXCITING.

3423
02:15:35,160 --> 02:15:39,680
FOR THOSE OF US FAMILIAR WITH

3424
02:15:39,680 --> 02:15:41,560
NCCIH'S PORTFOLIO, IT'S ALSO

3425
02:15:41,560 --> 02:15:44,920
VERY CONGRUENT WITH A LOT OF THE

3426
02:15:44,920 --> 02:15:46,360
WHOLE SYSTEMS APPROACHES AND

3427
02:15:46,360 --> 02:15:47,440
COMPLEMENTARY AND INTEGRATIVE

3428
02:15:47,440 --> 02:15:49,360
HEALTH.

3429
02:15:49,360 --> 02:15:51,040
WE MIGHT CALL THESE DIFFERENT

3430
02:15:51,040 --> 02:15:53,120
THINGS, IT'S THAT FOR A LONG

3431
02:15:53,120 --> 02:15:54,240
TIME THE WHOLE SYSTEMS

3432
02:15:54,240 --> 02:15:55,440
APPROACHES HAVE BEEN LOOKING AT

3433
02:15:55,440 --> 02:15:56,560
THINGS THIS WAY.

3434
02:15:56,560 --> 02:16:01,880
SO THIS LOOKS WONDERFUL.

3435
02:16:01,880 --> 02:16:03,200
 

3436
02:16:03,200 --> 02:16:03,520
>> GREAT.

3437
02:16:03,520 --> 02:16:07,800
THANK YOU. 

3438
02:16:07,800 --> 02:16:08,280
DR. SHERMAN?

3439
02:16:08,280 --> 02:16:11,040
>>  I SUSPECT THAT RONI STOLE A

3440
02:16:11,040 --> 02:16:13,560
LITTLE BIT OF MY THUNDER.

3441
02:16:13,560 --> 02:16:15,080
I'LL RECONCEPTUALIZE A LITTLE

3442
02:16:15,080 --> 02:16:18,800
BIT AND DO SOME SPECULATION

3443
02:16:18,800 --> 02:16:19,760
FURTHER OUT.

3444
02:16:19,760 --> 02:16:22,840
MAYBE BECAUSE TOWARD THE END OF

3445
02:16:22,840 --> 02:16:25,800
MY CAREER, I FEEL LIKE I CAN SEE

3446
02:16:25,800 --> 02:16:27,320
SOME WAYS THINGS CAN GO INTO THE

3447
02:16:27,320 --> 02:16:27,680
FUTURE.

3448
02:16:27,680 --> 02:16:31,280
FOR ONE THING, I LOVE THE IDEA.

3449
02:16:31,280 --> 02:16:34,240
I THINK IT PROVIDES A FRAMEWORK

3450
02:16:34,240 --> 02:16:36,840
FOR THE DEVELOPMENT OF THE BEST

3451
02:16:36,840 --> 02:16:45,560
SETS OF THERAPIES AND POSSIBLY

3452
02:16:45,560 --> 02:16:46,240
BY UNDERSTANDING THE BIOLOGY

3453
02:16:46,240 --> 02:16:47,560
SOME KIND OF IDEA WHAT YOU HAVE

3454
02:16:47,560 --> 02:16:48,120
TO DO FIRST.

3455
02:16:48,120 --> 02:16:50,360
DO YOU HAVE TO STRETCH THE

3456
02:16:50,360 --> 02:16:53,800
TISSUE, SAY, IN A MORE PHYSICAL

3457
02:16:53,800 --> 02:16:56,760
INTERVENTION FOR OPTIMAL RESULTS

3458
02:16:56,760 --> 02:16:59,280
BEFORE YOU UNDERTAKE, YOU KNOW,

3459
02:16:59,280 --> 02:17:04,320
YOGA STRETCHING OR TAI CHI,

3460
02:17:04,320 --> 02:17:06,040
THINGS THAT WILL BE INTERESTING

3461
02:17:06,040 --> 02:17:12,440
AND THEN CAN BE CUSTOMIZED BY 

3462
02:17:12,440 --> 02:17:13,920
PHYSICAL THERAPISTS AND OTHERS

3463
02:17:13,920 --> 02:17:15,400
AS WE BETTER UNDERSTAND HOW IT

3464
02:17:15,400 --> 02:17:21,880
PROVIDES AND PROVIDES, TO MY 

3465
02:17:21,880 --> 02:17:26,280
WAY, A WAY OF UNDERSTANDING

3466
02:17:26,280 --> 02:17:29,760
THERAPIES LIKE YOGA AND TAI CHI

3467
02:17:29,760 --> 02:17:30,640
THAT HAVE DIFFERENT COMPONENTS

3468
02:17:30,640 --> 02:17:31,840
BUT HOW DO YOU PUT THEM

3469
02:17:31,840 --> 02:17:32,480
TOGETHER?

3470
02:17:32,480 --> 02:17:33,760
YOU MIGHT DO SOMETHING DIFFERENT

3471
02:17:33,760 --> 02:17:36,320
FOR A FOCUS ON THE JOINT THAN

3472
02:17:36,320 --> 02:17:44,280
FOR CARDIOVASCULAR OR OTHER

3473
02:17:44,280 --> 02:17:45,360
THINGS LIKE THAT.

3474
02:17:45,360 --> 02:17:46,800
THOSE COULD BE OPTIMIZED FOR

3475
02:17:46,800 --> 02:17:49,120
THOSE THAT PREFER SOMETHING

3476
02:17:49,120 --> 02:17:50,120
WITHOUT SCIENTIFIC NAMES, THAT

3477
02:17:50,120 --> 02:17:51,400
COULD STILL WORK REALLY WELL.

3478
02:17:51,400 --> 02:17:53,800
I LOVE THE IDEA OF EXTENDING

3479
02:17:53,800 --> 02:17:56,640
THIS TO OTHER SYSTEMS, USING THE

3480
02:17:56,640 --> 02:17:57,520
SAME FRAMEWORK.

3481
02:17:57,520 --> 02:18:00,400
I SUSPECT WE'LL FIND INTERESTING

3482
02:18:00,400 --> 02:18:01,800
DIFFERENCES AND FASCINATING

3483
02:18:01,800 --> 02:18:02,240
COMMONALITIES.

3484
02:18:02,240 --> 02:18:04,440
AFTER WE'VE DONE THIS FOR, I

3485
02:18:04,440 --> 02:18:10,800
DON'T KNOW, FIVE OR SYSTEMS

3486
02:18:10,800 --> 02:18:12,920
MAYBE THE 100th MONKEY WILL BE

3487
02:18:12,920 --> 02:18:14,800
THE FRAMEWORK FOR GENERAL

3488
02:18:14,800 --> 02:18:15,600
PREVENTION, TEACHING CHILDREN AT

3489
02:18:15,600 --> 02:18:17,760
2 YEARS OLD, 5 YEARS OLD, 10

3490
02:18:17,760 --> 02:18:19,480
YEARS OLD, FUN BY THE TIME THEY

3491
02:18:19,480 --> 02:18:21,440
ARE TEENAGERS TO REBEL AGAINST

3492
02:18:21,440 --> 02:18:23,200
THEIR PARENTS BY BEING REALLY

3493
02:18:23,200 --> 02:18:24,520
HEALTHY OR WHATEVER.

3494
02:18:24,520 --> 02:18:25,560
MOVE THAT OUT.

3495
02:18:25,560 --> 02:18:27,360
BUT THOSE ARE SOME OF THE THINGS

3496
02:18:27,360 --> 02:18:32,720
THAT POPPED INTO MY MIND.

3497
02:18:32,720 --> 02:18:34,680
YOU HAVE ON THE FORM THAT TURNS

3498
02:18:34,680 --> 02:18:38,400
OUT TO BE TRUE, I THINK IT'S A

3499
02:18:38,400 --> 02:18:41,680
VERY USEFUL HUERISTIC, SO THANK

3500
02:18:41,680 --> 02:18:47,560
YOU SO MUCH.

3501
02:18:47,560 --> 02:18:49,440
>> THANK YOU.

3502
02:18:49,440 --> 02:18:51,960
>> ANY OTHER COMMENTS?

3503
02:18:51,960 --> 02:18:53,160
>> I'M WONDERING IF I CAN SEE

3504
02:18:53,160 --> 02:18:54,280
MORE DISCUSSION.

3505
02:18:54,280 --> 02:18:57,000
WE HAVE A GREAT COLLECTION OF

3506
02:18:57,000 --> 02:18:58,960
ACADEMICS HERE ON COUNCIL FROM

3507
02:18:58,960 --> 02:19:01,280
THEIR OWN INSTITUTIONS, ALL OF

3508
02:19:01,280 --> 02:19:03,920
WHOM -- MANY OF WHOM HAVE BEEN

3509
02:19:03,920 --> 02:19:06,320
INVOLVED IN THIS.

3510
02:19:06,320 --> 02:19:07,920
I'M THINKING JUST BECAUSE TONY

3511
02:19:07,920 --> 02:19:12,920
HAPPENS TO BE ON MY HOLLYWOOD

3512
02:19:12,920 --> 02:19:15,440
SQUARES HERE HOW WOULD THIS BE

3513
02:19:15,440 --> 02:19:19,080
TAUGHT, AS WELL AS RESEARCHED,

3514
02:19:19,080 --> 02:19:21,760
IN YOUR RESPECTIVE INSTITUTIONS.

3515
02:19:21,760 --> 02:19:25,600
BOTH DR. CRISWELL AND DR. 

3516
02:19:25,600 --> 02:19:26,680
LANGEVIN PROPOSED SOMETHING

3517
02:19:26,680 --> 02:19:28,960
FAIRLY BOLD IN LOOKING AT BOTH

3518
02:19:28,960 --> 02:19:31,520
OF RE-JOIN INITIATIVE AND THE

3519
02:19:31,520 --> 02:19:33,560
WHOLE JOINT HEALTH, HOW DO YOU

3520
02:19:33,560 --> 02:19:40,160
THINK ABOUT THIS IN YOUR OWN

3521
02:19:40,160 --> 02:19:41,600
INSTITUTIONS, ACADEMIC SILOS

3522
02:19:41,600 --> 02:19:43,640
THAT ANY INSTITUTION HAS.

3523
02:19:43,640 --> 02:19:46,160
>> IF YOU PICKED ON ME FIRST,

3524
02:19:46,160 --> 02:19:52,280
WHAT WE TEACH FOLLOWS THE

3525
02:19:52,280 --> 02:19:54,360
EVIDENCE, WE NEED TO EXPLORE THE

3526
02:19:54,360 --> 02:19:56,880
EVIDENCE.

3527
02:19:56,880 --> 02:20:00,720
THE THING THAT INTRIGUES ME, NOT

3528
02:20:00,720 --> 02:20:02,760
JUST THE SCIENTIFIC PROCESS AND

3529
02:20:02,760 --> 02:20:09,520
ELIMINATING CAUSE OF CHRONIC

3530
02:20:09,520 --> 02:20:16,600
CONDITIONS THAT NEEDS TO EXPAND

3531
02:20:16,600 --> 02:20:24,520
OF WHOLE BODY, TO DEVELOP WHOLE 

3532
02:20:24,520 --> 02:20:32,360
BODY  ENTIRE VENGES AND  --

3533
02:20:32,360 --> 02:20:34,920
INTERVENTION AND COMPARE THEM.

3534
02:20:34,920 --> 02:20:37,640
MUSCULOSKELETAL, WE'RE SPENDING

3535
02:20:37,640 --> 02:20:39,720
ENORMOUS  ENORMOUS AMOUNT OF

3536
02:20:39,720 --> 02:20:41,360
MONEY ON LOW VALUE CARE, LOOKING

3537
02:20:41,360 --> 02:20:43,240
FOR THE STRAW DOG TO COMPARE

3538
02:20:43,240 --> 02:20:44,600
THAT BUT IMAGINE THE COMPARATOR,

3539
02:20:44,600 --> 02:20:46,960
SOMETHING THAT HAS A BASIS AND

3540
02:20:46,960 --> 02:20:49,880
CAN BE EFFECTIVE, THAT COULD

3541
02:20:49,880 --> 02:20:51,520
REALLY TURN THE TIDE ON SOME OF

3542
02:20:51,520 --> 02:20:52,720
THE LOW VALUE CARE THAT'S GOING

3543
02:20:52,720 --> 02:20:54,080
ON OUT THERE.

3544
02:20:54,080 --> 02:20:57,200
IT WOULD BE HARD, IT'S ONE THING

3545
02:20:57,200 --> 02:20:58,960
TO SAY, GEE, THIS INTERVENTION

3546
02:20:58,960 --> 02:21:02,560
WAS EQUAL TO SURGERY FOR LUMBAR

3547
02:21:02,560 --> 02:21:03,560
SPINAL STENOSIS, ANOTHER THING

3548
02:21:03,560 --> 02:21:05,840
TO SAY THIS INTERVENTION IS

3549
02:21:05,840 --> 02:21:10,560
BETTER FOR THE PERSON AND

3550
02:21:10,560 --> 02:21:11,720
OUTCOME IS WAY BETTER THAN

3551
02:21:11,720 --> 02:21:13,320
SURGERY, THAT WOULD BE A GAME

3552
02:21:13,320 --> 02:21:22,160
CHANGER FOR THE HEALTH SYSTEMS

3553
02:21:22,160 --> 02:21:23,760
OUT THERE.

3554
02:21:23,760 --> 02:21:24,200
>> THANK YOU.

3555
02:21:24,200 --> 02:21:24,400
LORI?

3556
02:21:24,400 --> 02:21:27,720
>>  I WANT TO APPLAUD THIS

3557
02:21:27,720 --> 02:21:27,960
EFFORT.

3558
02:21:27,960 --> 02:21:29,160
BEING A PAIN CLINICIAN FOR THE

3559
02:21:29,160 --> 02:21:31,320
FIRST 20 YEARS OF MY CAREER THIS

3560
02:21:31,320 --> 02:21:32,560
IS MUSIC TO MY CAREERS.

3561
02:21:32,560 --> 02:21:35,800
I WANT TO LINK THIS TO THE

3562
02:21:35,800 --> 02:21:36,960
CLINICAL ENVIRONMENT AND

3563
02:21:36,960 --> 02:21:38,120
VALUE-BASED PAYMENT.

3564
02:21:38,120 --> 02:21:39,760
THE TIMING COULDN'T BE MORE

3565
02:21:39,760 --> 02:21:40,520
RIGHT.

3566
02:21:40,520 --> 02:21:42,160
AS WE'RE LOOKING AT NOT ONE

3567
02:21:42,160 --> 02:21:45,360
INTERVENTION IN FREE FOR 

3568
02:21:45,360 --> 02:21:46,960
S ERVICE -- FEE FOR SERVICE BUT

3569
02:21:46,960 --> 02:21:49,160
THE WHOLE PERSON OVER THE

3570
02:21:49,160 --> 02:21:52,560
LIFETIME, THIS IS AN IMPERATIVE

3571
02:21:52,560 --> 02:21:53,120
TO THAT.

3572
02:21:53,120 --> 02:22:01,120
I'M NEW TO THE COUNCIL, MY FIRST

3573
02:22:01,120 --> 02:22:07,000
DAY, ALREADY SO INSPIRED.

3574
02:22:07,000 --> 02:22:15,640
>> OTHER COMMENTS OR QUESTIONS

3575
02:22:15,640 --> 02:22:16,480
BY COUNCIL MEMBERS?

3576
02:22:16,480 --> 02:22:19,760
>> I WAS GOING TO ASK A

3577
02:22:19,760 --> 02:22:20,000
QUESTION.

3578
02:22:20,000 --> 02:22:22,200
I WANTED TO DEFER TO THOSE ON

3579
02:22:22,200 --> 02:22:26,360
COUNCIL FIRST.

3580
02:22:26,360 --> 02:22:27,120
>> DR. SONNENBERG?

3581
02:22:27,120 --> 02:22:29,120
>>  THIS WAS A REALLY BEAUTIFUL

3582
02:22:29,120 --> 02:22:31,320
PICTURE THAT YOU BOTH SKETCHED.

3583
02:22:31,320 --> 02:22:34,440
I THINK WHAT MAY BE EVEN MORE

3584
02:22:34,440 --> 02:22:36,080
EXCITING IS THE POSSIBILITY OF

3585
02:22:36,080 --> 02:22:46,040
USING THIS AS   TEMPLATE.

3586
02:22:46,040 --> 02:22:47,560
ANALOGY TO DIGESTIVE SYSTEM AT

3587
02:22:47,560 --> 02:22:48,880
THE END WAS POTENTIALLY EXAMPLE

3588
02:22:48,880 --> 02:22:53,560
OF THAT BUT I'M CURIOUS IF THERE

3589
02:22:53,560 --> 02:22:55,680
ARE OTHER AREAS THAT ARE AT THE

3590
02:22:55,680 --> 02:22:57,640
KIND OF FRONT OF YOUR MIND WHERE

3591
02:22:57,640 --> 02:23:00,160
THIS COULD BE OVERLAID AND

3592
02:23:00,160 --> 02:23:03,640
EXPANDED BECAUSE I THINK, YOU

3593
02:23:03,640 --> 02:23:05,160
KNOW, INTEGRATIVE VIEW OF

3594
02:23:05,160 --> 02:23:07,720
SYSTEMS IS WHAT'S ON THE HORIZON

3595
02:23:07,720 --> 02:23:10,080
HERE, AND SO I THINK THAT, YEAH,

3596
02:23:10,080 --> 02:23:11,720
I'D BE CURIOUS TO HEAR YOUR

3597
02:23:11,720 --> 02:23:15,960
THOUGHTS WHERE THIS COULD 

3598
02:23:15,960 --> 02:23:16,400
EXPAND.

3599
02:23:16,400 --> 02:23:17,200
>> WELL, WE'VE BEEN SPENDING

3600
02:23:17,200 --> 02:23:18,360
TIME THINKING ABOUT THAT.

3601
02:23:18,360 --> 02:23:20,520
WE HAD A WORKSHOP ON WHOLE

3602
02:23:20,520 --> 02:23:22,960
PERSON RESEARCH, RIGHT?

3603
02:23:22,960 --> 02:23:26,000
AND PART OF THAT, THE FIRST

3604
02:23:26,000 --> 02:23:30,080
SESSION OF THAT WAS ABOUT

3605
02:23:30,080 --> 02:23:31,720
INTERCONNECTED SYSTEMS, SOME OF

3606
02:23:31,720 --> 02:23:34,080
THE PRESENTATIONS AT THAT

3607
02:23:34,080 --> 02:23:35,640
WORKSHOP WERE UNBELIEVABLE.

3608
02:23:35,640 --> 02:23:40,120
AND I THINK THE PLACE WHERE WE

3609
02:23:40,120 --> 02:23:41,800
NEED TO INTEGRATE, THERE ARE

3610
02:23:41,800 --> 02:23:44,360
SOME SYSTEMS, FOR EXAMPLE,

3611
02:23:44,360 --> 02:23:45,760
IMMUNE OR ENDOCRINE SYSTEM, SORT

3612
02:23:45,760 --> 02:23:46,560
OF INTEGRATED ALREADY.

3613
02:23:46,560 --> 02:23:50,760
THEY INTERACT WITH THE WHOLE

3614
02:23:50,760 --> 02:23:51,400
BODY.

3615
02:23:51,400 --> 02:23:54,160
BUT EVEN LIKE THE ENDOCRINE

3616
02:23:54,160 --> 02:23:56,720
SYSTEM, WHERE DOES IT INTERFACE

3617
02:23:56,720 --> 02:23:59,800
WITH OTHER SYSTEMS, FOR EXAMPLE,

3618
02:23:59,800 --> 02:24:03,600
THE MUSCULOSKELETAL SYSTEM OR

3619
02:24:03,600 --> 02:24:04,840
IMMUNE SYSTEM, THAT'S THE KIND

3620
02:24:04,840 --> 02:24:06,960
OF INTERFACE WHERE WE CAN REALLY

3621
02:24:06,960 --> 02:24:10,160
START MAKING SOME PROGRESS.

3622
02:24:10,160 --> 02:24:13,560
SO IMAGINE THINKING REPRODUCTIVE

3623
02:24:13,560 --> 02:24:13,800
HEALTH.

3624
02:24:13,800 --> 02:24:15,080
IT'S OB/GYN, RIGHT?

3625
02:24:15,080 --> 02:24:17,760
IT'S A LOT MORE BECAUSE YOU HAVE

3626
02:24:17,760 --> 02:24:20,120
ALL THESE PELVIC ORGANS SITTING

3627
02:24:20,120 --> 02:24:21,680
THERE, WELL, THERE'S STUFF

3628
02:24:21,680 --> 02:24:22,400
AROUND THEM.

3629
02:24:22,400 --> 02:24:24,160
AND THEY ARE SITTING RIGHT NEXT

3630
02:24:24,160 --> 02:24:25,880
TO, GUESS WHAT, THE BLADDER.

3631
02:24:25,880 --> 02:24:27,240
THEY ARE SITTING NEXT TO THE

3632
02:24:27,240 --> 02:24:27,440
COLON.

3633
02:24:27,440 --> 02:24:31,560
THEY ARE SITTING RIGHT NEXT TO

3634
02:24:31,560 --> 02:24:32,560
THE LUMBAR SPINE AND SACRUM.

3635
02:24:32,560 --> 02:24:38,160
THERE'S A LOT OF THINGS THERE.

3636
02:24:38,160 --> 02:24:39,680
WE DON'T THINK ANATOMICALLY.

3637
02:24:39,680 --> 02:24:44,480
WE THINK ONE SYSTEM AT A TIME. 

3638
02:24:44,480 --> 02:24:46,160
OF COURSE THE ENDOCRINE SYSTEM

3639
02:24:46,160 --> 02:24:47,640
IS BATHING ALL OF THIS, I COULD

3640
02:24:47,640 --> 02:24:48,560
KEEP GOING.

3641
02:24:48,560 --> 02:24:50,400
YOU SEE WHAT I MEAN?

3642
02:24:50,400 --> 02:24:52,040
THERE'S DIFFERENT INTEGRATION.

3643
02:24:52,040 --> 02:24:52,800
THERE'S ACROSS SYSTEM AND THE

3644
02:24:52,800 --> 02:24:55,120
MOST INTERESTING IN MY OPINION

3645
02:24:55,120 --> 02:24:57,600
IS ACROSS ANATOMY BECAUSE THAT

3646
02:24:57,600 --> 02:24:59,360
TENDS TO GET FOSSILIZED, JUST

3647
02:24:59,360 --> 02:25:01,760
LIKE WHEN WE TALKED ABOUT

3648
02:25:01,760 --> 02:25:05,160
DIFFERENT PARTS OF THE JOINT.

3649
02:25:05,160 --> 02:25:06,920
THE MYOFASCIAL TISSUES HAVE BEEN

3650
02:25:06,920 --> 02:25:10,760
LEFT OUT OF ANATOMY FOR

3651
02:25:10,760 --> 02:25:11,040
CENTURIES.

3652
02:25:11,040 --> 02:25:12,400
THEY ARE NOT EVEN THERE.

3653
02:25:12,400 --> 02:25:16,480
THEY ARE NOT EVEN PART OF HOW WE

3654
02:25:16,480 --> 02:25:17,760
THINK OF ANATOMY.

3655
02:25:17,760 --> 02:25:24,560
THERE'S A LOT OF POTENTIAL OUT

3656
02:25:24,560 --> 02:25:24,760
THERE.

3657
02:25:24,760 --> 02:25:27,040
>> DR. LOREETSKI AND DR. HENSON?

3658
02:25:27,040 --> 02:25:30,680
>>  I'M RESPONDING ABOUT HOW TO

3659
02:25:30,680 --> 02:25:35,960
TEACH THIS INTEGRATION OR WHOLE

3660
02:25:35,960 --> 02:25:36,840
PERSON APPROACH.

3661
02:25:36,840 --> 02:25:38,440
POST-COVID, PUT IS IN THE

3662
02:25:38,440 --> 02:25:40,400
SESSION WHEN IT'S NECESSARY TO

3663
02:25:40,400 --> 02:25:41,760
DO SO.

3664
02:25:41,760 --> 02:25:44,560
I RUN A POST-COVID CLINIC IN

3665
02:25:44,560 --> 02:25:47,120
INDUSTRY BUT I INTERACT WITH

3666
02:25:47,120 --> 02:25:48,280
OTHER SUBSPECIALITIES THAT ARE

3667
02:25:48,280 --> 02:25:50,720
TAKING CARE OF PATIENTS, AND

3668
02:25:50,720 --> 02:25:54,240
SUCH APPROACH IS NECESSARY, LIKE

3669
02:25:54,240 --> 02:25:57,560
RECONSTRUCTING OUR HEALTH CARE 

3670
02:25:57,560 --> 02:25:59,000
SYSTEM AND RESEARCH THAT'S

3671
02:25:59,000 --> 02:26:01,960
COLLABORATIVE IN NATURE.

3672
02:26:01,960 --> 02:26:04,480
POST-COVID CARE PRESENTED THIS

3673
02:26:04,480 --> 02:26:08,320
OPPORTUNITY TO RETHINK HOW WE

3674
02:26:08,320 --> 02:26:08,800
APPROACH PROBLEMS.

3675
02:26:08,800 --> 02:26:15,360
>> THANK YOU.

3676
02:26:15,360 --> 02:26:15,680
DR. HENSEL?

3677
02:26:15,680 --> 02:26:17,000
>> I WAS REALLY GLAD TO HEAR

3678
02:26:17,000 --> 02:26:19,760
WHAT YOU WERE JUST TALKING

3679
02:26:19,760 --> 02:26:21,960
ABOUT, AND WHAT YOU JUST SAID

3680
02:26:21,960 --> 02:26:25,000
COULD HAVE REALLY BEEN A WELCOME

3681
02:26:25,000 --> 02:26:28,160
TO OSTEOPATHIC MEDICAL SCHOOL

3682
02:26:28,160 --> 02:26:28,480
PRESENTATION.

3683
02:26:28,480 --> 02:26:30,440
BECAUSE THAT'S EXACTLY HOW WE

3684
02:26:30,440 --> 02:26:30,800
TEACH.

3685
02:26:30,800 --> 02:26:32,480
WHEN WE'RE TEACHING ON OUR

3686
02:26:32,480 --> 02:26:33,680
APPROACH TO THE MUSCULOSKELETAL

3687
02:26:33,680 --> 02:26:35,920
SYSTEM WE ACTUALLY BREAK IT DOWN

3688
02:26:35,920 --> 02:26:38,560
BY SYSTEMS.

3689
02:26:38,560 --> 02:26:40,760
WE TEACH INTERACTING WITH THE

3690
02:26:40,760 --> 02:26:42,120
RESPIRATORY SYSTEM AND

3691
02:26:42,120 --> 02:26:44,160
TECHNIQUES THAT APPROACH THAT OR

3692
02:26:44,160 --> 02:26:47,080
INTERACTING WITH THE G.I. SYSTEM

3693
02:26:47,080 --> 02:26:47,960
OR REPRODUCTIVE SYSTEM.

3694
02:26:47,960 --> 02:26:50,800
ENDOCRINE IS A LOT MORE

3695
02:26:50,800 --> 02:26:51,160
THEORETICAL.

3696
02:26:51,160 --> 02:26:56,160
AS YOU CAN PROBABLY IMAGINE, WE 

3697
02:26:56,160 --> 02:26:59,000
DO HAVE SOME ANATOMICAL -- A LOT

3698
02:26:59,000 --> 02:27:02,160
OF OUR CRANIAL TECHNIQUES MANY

3699
02:27:02,160 --> 02:27:04,240
BODY WORKERS ALSO DO, THEORIZED

3700
02:27:04,240 --> 02:27:06,560
TO HAVE SOME EFFECT ON THE

3701
02:27:06,560 --> 02:27:07,440
ENDOCRINE SYSTEM.

3702
02:27:07,440 --> 02:27:12,080
WE DON'T HAVE A LOT OF DATA ON

3703
02:27:12,080 --> 02:27:12,960
IT.

3704
02:27:12,960 --> 02:27:15,960
BUT IT'S SOMETHING THAT WE'VE

3705
02:27:15,960 --> 02:27:18,320
TAUGHT FOR 140 YEARS THAT THE

3706
02:27:18,320 --> 02:27:21,720
INTERACTION BETWEEN THE BODY

3707
02:27:21,720 --> 02:27:23,200
SYSTEMS, THAT THE SILOS WHERE

3708
02:27:23,200 --> 02:27:26,120
IT'S TAUGHT SOMETIMES, WHERE

3709
02:27:26,120 --> 02:27:27,600
IT'S RESEARCHED OR TREATED

3710
02:27:27,600 --> 02:27:31,560
SOMETIMES, IS A FALSE

3711
02:27:31,560 --> 02:27:32,320
DELINEATION.

3712
02:27:32,320 --> 02:27:35,040
REALLY THAT YOU CAN'T SEPARATE

3713
02:27:35,040 --> 02:27:35,800
RESPIRATORY FROM G.I., WHEN YOU

3714
02:27:35,800 --> 02:27:38,840
START TALKING ABOUT THE MOTION

3715
02:27:38,840 --> 02:27:47,280
OF THE DIAPHRAGM AND HOW THAT

3716
02:27:47,280 --> 02:27:50,480
AFFECTS PERISTALSIS IN THE GUT.

3717
02:27:50,480 --> 02:27:53,520
ASK ANYBODY WHO HAD A COUGH, CAN

3718
02:27:53,520 --> 02:27:56,240
YOU SEPARATE MUSCULOSKELETAL 

3719
02:27:56,240 --> 02:27:59,400
FROM RESPIRATORY?  IF YOU GET

3720
02:27:59,400 --> 02:28:04,480
THE RIBS OR DIAPHRAGM  SORE FROM

3721
02:28:04,480 --> 02:28:06,840
THE COUGH, IT'S HARDER TO HEAL

3722
02:28:06,840 --> 02:28:08,160
FROM THE RESPIRATORY INSULT OF

3723
02:28:08,160 --> 02:28:09,960
THE INSTEAD OF THINKING OF SILOS

3724
02:28:09,960 --> 02:28:13,280
WE THINK OF MORE OF AN

3725
02:28:13,280 --> 02:28:14,800
INTERMESHING BETWEEN THE SYSTEMS

3726
02:28:14,800 --> 02:28:17,880
AND MUSCULOSKELETAL SYSTEM AND

3727
02:28:17,880 --> 02:28:19,160
HOW WE ACCESS THROUGH

3728
02:28:19,160 --> 02:28:19,560
MUSCULOSKELETAL.

3729
02:28:19,560 --> 02:28:22,680
SO I'M VERY EXCITED TO HEAR THAT

3730
02:28:22,680 --> 02:28:23,760
THAT'S -- THAT THE THOUGHT WE'VE

3731
02:28:23,760 --> 02:28:29,360
HAD FOR A LONG TIME IS GAINING

3732
02:28:29,360 --> 02:28:31,160
SOME MORE MAINSTREAM LEGITIMACY.

3733
02:28:31,160 --> 02:28:32,880
>> IT HAS A WAYS TO GO.

3734
02:28:32,880 --> 02:28:34,800
I WANT TO APOLOGIZE.

3735
02:28:34,800 --> 02:28:37,120
I SAID IT'S MISSING, I MEANT

3736
02:28:37,120 --> 02:28:37,960
FROM CONVENTIONAL SCHOOLS BUT

3737
02:28:37,960 --> 02:28:42,000
CERTAINLY NOT FROM  OSTEOPATHIC

3738
02:28:42,000 --> 02:28:42,440
SCHOOLS.

3739
02:28:42,440 --> 02:28:51,400
SO WE HAVE A LOT TO LEARN FROM

3740
02:28:51,400 --> 02:28:52,080
YOU ALL.

3741
02:28:52,080 --> 02:28:55,440
>> I YOU WANT TO ADDRESS HOW TO

3742
02:28:55,440 --> 02:28:56,000
EDUCATE.

3743
02:28:56,000 --> 02:28:59,760
ANOTHER WAY IS TO MAYBE BRING

3744
02:28:59,760 --> 02:29:01,800
STUDENTS TOGETHER FROM DIFFERENT

3745
02:29:01,800 --> 02:29:02,360
DISCIPLINES.

3746
02:29:02,360 --> 02:29:11,840
YOU KNOW, I ACTUALLY TEACH AND 

3747
02:29:11,840 --> 02:29:12,920
INTERDISCIPLINARY COURSE ON PAIN

3748
02:29:12,920 --> 02:29:16,080
IN UNIVERSITY OF MINNESOTA WHERE

3749
02:29:16,080 --> 02:29:19,240
WE INTEGRATE NURSES, 

3750
02:29:19,240 --> 02:29:20,680
PSYCHOLOGISTS, THEY HAVE LEARNED

3751
02:29:20,680 --> 02:29:21,760
ABOUT APPROACHES TO PAIN, A FUN

3752
02:29:21,760 --> 02:29:23,560
WAY TO THINK ABOUT THIS MORE.

3753
02:29:23,560 --> 02:29:24,760
THEN MAYBE, YOU KNOW, IN TERMS

3754
02:29:24,760 --> 02:29:26,640
OF THE RESEARCH THAT WE DO,

3755
02:29:26,640 --> 02:29:28,360
MAYBE THERE'S SOMETHING IN TERMS

3756
02:29:28,360 --> 02:29:30,880
OF SOME RFAs THAT COME OUT

3757
02:29:30,880 --> 02:29:33,720
THAT REQUIRE SOME OF THIS

3758
02:29:33,720 --> 02:29:35,440
INTERDISCIPLINARY COLLABORATION,

3759
02:29:35,440 --> 02:29:38,760
YOU KNOW, TO REALLY -- A LITTLE

3760
02:29:38,760 --> 02:29:41,360
BIT MORE PROVOKING OR, YOU KNOW,

3761
02:29:41,360 --> 02:29:43,120
ENCOURAGEMENT BECAUSE I THINK WE

3762
02:29:43,120 --> 02:29:44,560
ALL DO HAVE DIFFERENT

3763
02:29:44,560 --> 02:29:46,600
PERSPECTIVES BUT WE CAN DO IT

3764
02:29:46,600 --> 02:29:49,240
WITHIN THE DISCIPLINE, A WHOLE

3765
02:29:49,240 --> 02:29:53,720
SYSTEM APPROACH, BUT THERE'S

3766
02:29:53,720 --> 02:29:54,720
SOMETHING REALLY UNIQUE AND

3767
02:29:54,720 --> 02:29:56,560
MAYBE WILL HELP US GET A LITTLE

3768
02:29:56,560 --> 02:30:05,360
BIT FURTHER IF WE CAN BRING

3769
02:30:05,360 --> 02:30:06,160
DIFFERENT DISCIPLINES TOGETHER.

3770
02:30:06,160 --> 02:30:07,480
>> THANK YOU.

3771
02:30:07,480 --> 02:30:10,520
OTHER QUESTIONS, COMMENTS FROM

3772
02:30:10,520 --> 02:30:10,880
COUNCIL?

3773
02:30:10,880 --> 02:30:16,400
>>  IF I CAN POSE A QUESTION.

3774
02:30:16,400 --> 02:30:18,600
HELENE, YOU'VE OUTLINED THIS

3775
02:30:18,600 --> 02:30:21,560
AMBITIOUS AND EXCITING RESEARCH

3776
02:30:21,560 --> 02:30:21,800
PROGRAM.

3777
02:30:21,800 --> 02:30:27,040
AND I WOULD BE INTERESTED IN

3778
02:30:27,040 --> 02:30:28,040
HEARING OR UNDERSTANDING HOW YOU

3779
02:30:28,040 --> 02:30:29,680
WOULD APPROACH THIS TO DEVELOP

3780
02:30:29,680 --> 02:30:33,760
THE EVIDENCE BASE, TO INFORM OUR

3781
02:30:33,760 --> 02:30:34,320
UNDERSTANDING, ULTIMATELY

3782
02:30:34,320 --> 02:30:36,000
IMPLEMENTATION, ET CETERA.

3783
02:30:36,000 --> 02:30:37,960
AND, YOU KNOW, IS THERE -- ARE

3784
02:30:37,960 --> 02:30:39,400
THERE EXAMPLES YOU CAN POINT TO

3785
02:30:39,400 --> 02:30:42,480
WHERE THESE SORTS OF PROBLEMS

3786
02:30:42,480 --> 02:30:44,200
WERE TACKLED SUCCESSFULLY, AND

3787
02:30:44,200 --> 02:30:45,880
ACQUIRED, YOU KNOW, INFORMED

3788
02:30:45,880 --> 02:30:47,800
KIND OF UNDERSTANDING ABOUT

3789
02:30:47,800 --> 02:30:50,960
WHOLE BODY HEALTH AND THEN

3790
02:30:50,960 --> 02:30:51,440
IMPLEMENT IT.

3791
02:30:51,440 --> 02:30:52,960
DO YOU HAVE A ROAD MAP OR WILL

3792
02:30:52,960 --> 02:30:55,360
THIS BE A FIRST OF ITS KIND SORT

3793
02:30:55,360 --> 02:30:56,240
OF STUDY?

3794
02:30:56,240 --> 02:30:58,480
I'D LOVE TO HEAR A LITTLE BIT

3795
02:30:58,480 --> 02:30:59,640
MORE FROM YOUR PERSPECTIVE.

3796
02:30:59,640 --> 02:31:00,360
>> GREAT QUESTION.

3797
02:31:00,360 --> 02:31:01,720
FIRST OF ALL, WE'LL HAVE TO DO

3798
02:31:01,720 --> 02:31:02,960
IT TOGETHER, RIGHT?

3799
02:31:02,960 --> 02:31:05,760
I MEAN, AND I THINK THE FACT

3800
02:31:05,760 --> 02:31:07,320
THAT WE'RE SO GRATEFUL THAT

3801
02:31:07,320 --> 02:31:09,360
NIAMS DECIDED TO TAKE THE BULL

3802
02:31:09,360 --> 02:31:13,560
BY THE HORNS AND TACKLE THE VERY

3803
02:31:13,560 --> 02:31:15,200
FIRST QUESTION, FUNDAMENTAL ONE,

3804
02:31:15,200 --> 02:31:16,840
OF, YOU KNOW, MAPPING THE

3805
02:31:16,840 --> 02:31:19,160
SENSORY NEURONS, I THINK THAT

3806
02:31:19,160 --> 02:31:23,840
THAT WAS SUCH AN IMPORTANT THING

3807
02:31:23,840 --> 02:31:24,280
TO DO.

3808
02:31:24,280 --> 02:31:25,480
AND, YOU KNOW, BECAUSE NIAMS IS

3809
02:31:25,480 --> 02:31:27,440
THE LEAD ON IT BUT ALSO OF

3810
02:31:27,440 --> 02:31:32,480
COURSE WITH THE COLLABORATION OF

3811
02:31:32,480 --> 02:31:38,960
NINDS AND NIDCR AND NCCIH AND 

3812
02:31:38,960 --> 02:31:40,680
NIBIB IS ALSO COLLABORATING.

3813
02:31:40,680 --> 02:31:42,400
WE NEED TO GET OUR HEADS

3814
02:31:42,400 --> 02:31:43,520
TOGETHER AND SAY, OKAY, LET'S

3815
02:31:43,520 --> 02:31:44,520
START WITH THAT.

3816
02:31:44,520 --> 02:31:46,440
YOU KNOW, LET'S START WITH

3817
02:31:46,440 --> 02:31:48,160
UNDERSTANDING WHERE THE SENSORY

3818
02:31:48,160 --> 02:31:49,160
NERVES ARE.

3819
02:31:49,160 --> 02:31:53,560
AND THEN HOW DO THEY CHANGE IN

3820
02:31:53,560 --> 02:31:55,520
THE PRESENCE OF DISEASE GOING

3821
02:31:55,520 --> 02:31:58,840
TOWARDS DISEASE, AND THEN ONCE

3822
02:31:58,840 --> 02:32:00,480
WE HAVE ESTABLISHED A KIND OF

3823
02:32:00,480 --> 02:32:03,320
SET OF MEASURES THAT WE COULD

3824
02:32:03,320 --> 02:32:05,720
USE TO FOLLOW THAT, THEN PERHAPS

3825
02:32:05,720 --> 02:32:08,160
GO TO BACPAC AND SEE HOW THIS

3826
02:32:08,160 --> 02:32:10,960
COULD BE -- THE TYPE OF MODELING

3827
02:32:10,960 --> 02:32:12,560
YOU'VE DESCRIBED, THAT IS YOU'RE

3828
02:32:12,560 --> 02:32:14,120
LEARNING SO MUCH AT NIAMS ABOUT,

3829
02:32:14,120 --> 02:32:16,280
YOU KNOW, ABOUT HOW TO INTEGRATE

3830
02:32:16,280 --> 02:32:18,040
ALL THESE MEASURES INTO A

3831
02:32:18,040 --> 02:32:19,040
COMPREHENSIVE MODEL THAT COULD

3832
02:32:19,040 --> 02:32:19,560
BE TESTED.

3833
02:32:19,560 --> 02:32:22,960
AND THEN YOU CAN SEE, WELL,

3834
02:32:22,960 --> 02:32:26,120
OKAY, HOW CAN YOU THEN TRY TO

3835
02:32:26,120 --> 02:32:29,320
REVERSE THE DIRECTION OF THIS

3836
02:32:29,320 --> 02:32:30,600
PATHOPHYSIOLOGY WITH AN

3837
02:32:30,600 --> 02:32:31,160
INTERVENTION?

3838
02:32:31,160 --> 02:32:37,840
I SEE -- FIRST ANATOMY, YOU

3839
02:32:37,840 --> 02:32:40,040
KNOW, BIOMARKERS, MODELS, AND

3840
02:32:40,040 --> 02:32:40,920
THEN INTERVENTIONS.

3841
02:32:40,920 --> 02:32:42,000
THAT'S KIND OF HOW I THINK WE

3842
02:32:42,000 --> 02:32:44,760
COULD SORT OF ALL GET TOGETHER

3843
02:32:44,760 --> 02:32:46,840
AND ATTACK THIS PROBLEM.

3844
02:32:46,840 --> 02:32:47,960
DOES THAT MAKE SENSE?

3845
02:32:47,960 --> 02:32:48,800
>> WELL, YEAH, ABSOLUTELY.

3846
02:32:48,800 --> 02:32:50,560
I ALSO HAVE BEEN THINKING I

3847
02:32:50,560 --> 02:32:53,640
THINK THAT BETWEEN BACPAC AND

3848
02:32:53,640 --> 02:32:55,000
THE MYOFASCIAL PAIN EFFORT AND

3849
02:32:55,000 --> 02:32:57,560
RE-JOIN, THEY WILL ALL BE

3850
02:32:57,560 --> 02:32:59,400
MUTUALLY INFORMATIVE.

3851
02:32:59,400 --> 02:33:03,320
AND BENEFIT FROM, YOU KNOW,

3852
02:33:03,320 --> 02:33:04,120
FINDINGS AND OBSERVATIONS AND

3853
02:33:04,120 --> 02:33:06,760
MODEL DEVELOPMENT IN THE OTHERS.

3854
02:33:06,760 --> 02:33:11,080
SO I SEE THOSE THREE EFFORTS AS

3855
02:33:11,080 --> 02:33:14,760
BEING MUCHLY INFORMATIVE AND

3856
02:33:14,760 --> 02:33:15,240
COMPLEMENTARY.

3857
02:33:15,240 --> 02:33:16,120
>> YEAH, YEAH.

3858
02:33:16,120 --> 02:33:18,840
AND THE FACT THAT, YOU KNOW, I

3859
02:33:18,840 --> 02:33:20,960
WAS -- I THINK THAT ALL THESE

3860
02:33:20,960 --> 02:33:23,840
THINGS ARE GOING TO PLUG IN.

3861
02:33:23,840 --> 02:33:24,640
FOR EXAMPLE, THINKING MYOFASCIAL

3862
02:33:24,640 --> 02:33:27,480
PAIN, EVERYTHING WE LEARN ABOUT

3863
02:33:27,480 --> 02:33:29,440
MYOFASCIAL PAIN WILL INFORM BACK

3864
02:33:29,440 --> 02:33:30,320
PAIN, FOR SURE.

3865
02:33:30,320 --> 02:33:32,200
AND EVERYTHING THAT WE LEARN

3866
02:33:32,200 --> 02:33:34,720
ABOUT MYOFASCIAL PAIN WILL

3867
02:33:34,720 --> 02:33:35,720
INFORM JOINT PAIN.

3868
02:33:35,720 --> 02:33:37,200
BUT I DON'T THINK IT'S GOING TO

3869
02:33:37,200 --> 02:33:39,320
STOP THERE.

3870
02:33:39,320 --> 02:33:41,040
I THINK THAT EVERYTHING WE LEARN

3871
02:33:41,040 --> 02:33:43,240
ABOUT BACK PAIN THROUGH THE

3872
02:33:43,240 --> 02:33:46,400
EXERCISE OF BACPAC WILL THEN

3873
02:33:46,400 --> 02:33:48,040
HELP US TO OPERATIONALIZE I HOW

3874
02:33:48,040 --> 02:33:50,000
WE THINK ABOUT ALL THESE VARIOUS

3875
02:33:50,000 --> 02:33:51,880
FACTORS THAT PLAY INTO THIS

3876
02:33:51,880 --> 02:33:53,400
BECAUSE IT'S COMPLICATED.

3877
02:33:53,400 --> 02:34:00,000
AND I REALLY AM DELIGHTED BACPAC

3878
02:34:00,000 --> 02:34:00,680
IS INCORPORATING PSYCHOSOCIAL

3879
02:34:00,680 --> 02:34:02,680
ASPECTS, WHICH IS KEY.

3880
02:34:02,680 --> 02:34:03,800
YOU'VE ALREADY GOTTEN A REAL

3881
02:34:03,800 --> 02:34:07,040
GOOD START ON THIS.

3882
02:34:07,040 --> 02:34:09,560
YEAH, I THINK THAT WITHIN -- YOU

3883
02:34:09,560 --> 02:34:12,080
KNOW, IT WON'T GO IN A STRAIGHT 

3884
02:34:12,080 --> 02:34:14,000
LINE FOR SURE BUT ... IT WOULD

3885
02:34:14,000 --> 02:34:16,960
BE NICE TO SEE WHERE THIS ALL

3886
02:34:16,960 --> 02:34:17,160
GOES.

3887
02:34:17,160 --> 02:34:17,360
KAREN?

3888
02:34:17,360 --> 02:34:21,560
>>  SO IF I THINK ABOUT THIS,

3889
02:34:21,560 --> 02:34:25,080
HELENE, NORMALLY HE START AT THE

3890
02:34:25,080 --> 02:34:26,040
LOWEST LEVEL, ANATOMY BETTER

3891
02:34:26,040 --> 02:34:27,760
WORKED OUT, MOVE UP ONE LEVEL,

3892
02:34:27,760 --> 02:34:30,200
MIGHT GO BACK AND GET A LITTLE

3893
02:34:30,200 --> 02:34:31,520
MORE ANATOMY BECAUSE YOU LEARNED

3894
02:34:31,520 --> 02:34:31,960
SOMETHING NEW.

3895
02:34:31,960 --> 02:34:37,640
YOU KNOW, ADD SYSTEMS BIOLOGY,

3896
02:34:37,640 --> 02:34:39,160
BLAH, BLAH, BLAH, EVENTUALLY GET

3897
02:34:39,160 --> 02:34:42,360
INTERVENTION URGES  ENTER.

3898
02:34:42,360 --> 02:34:42,600
OF VENGES.

3899
02:34:42,600 --> 02:34:47,160
SOME  -- INTERVENTION.

3900
02:34:47,160 --> 02:34:49,320
SOME OF US WILL BE RETIRED OR

3901
02:34:49,320 --> 02:34:51,520
DEAD BY THIS TIME.

3902
02:34:51,520 --> 02:34:53,200
AS WE DEVELOP INTERVENTIONS MORE

3903
02:34:53,200 --> 02:34:54,560
BLACK-BOXY OR BASED ON BEST

3904
02:34:54,560 --> 02:34:56,360
EVIDENCE NOW ARE THERE THINGS WE

3905
02:34:56,360 --> 02:34:59,120
CAN DO THAT CAN HELP INFORM THIS

3906
02:34:59,120 --> 02:35:07,320
THING THAT'S COMING  BEHIND TO

3907
02:35:07,320 --> 02:35:08,720
NAIL THINGS DOWN FURTHER, ARE

3908
02:35:08,720 --> 02:35:10,560
THERE CLINICAL STUDIES OR WAYS

3909
02:35:10,560 --> 02:35:17,200
OF COLLECTING OBSERVATIONS THAT 

3910
02:35:17,200 --> 02:35:18,160
WILL FACILITATE EVERYTHING

3911
02:35:18,160 --> 02:35:18,400
QUICKER?

3912
02:35:18,400 --> 02:35:20,800
>>  I I'VE GOT TO CHIME IN.

3913
02:35:20,800 --> 02:35:22,240
GREAT QUESTION, KAREN.

3914
02:35:22,240 --> 02:35:25,080
I'M ON THE BACPAC STUDY I'M PART

3915
02:35:25,080 --> 02:35:27,800
OF THE BEST TRIAL DOING BRAIN

3916
02:35:27,800 --> 02:35:29,560
IMAGING, DOING ALL TYPES OF

3917
02:35:29,560 --> 02:35:29,880
INTERVENTIONS.

3918
02:35:29,880 --> 02:35:31,200
ONE OF THE INTERESTING THINGS

3919
02:35:31,200 --> 02:35:32,600
THAT DR. CRISWELL WAS SAYING

3920
02:35:32,600 --> 02:35:35,480
ABOUT THE BACPAC STUDY IS WE'RE

3921
02:35:35,480 --> 02:35:36,640
DOING INTERVENTIONAL

3922
02:35:36,640 --> 02:35:37,360
PHENOTYPING.

3923
02:35:37,360 --> 02:35:39,800
IN ESSENCE WE'RE USING DIFFERENT

3924
02:35:39,800 --> 02:35:41,240
INTERVENTIONS, NOT AS A WAY TO

3925
02:35:41,240 --> 02:35:42,920
SAY ONE INTERVENTION IS BETTER

3926
02:35:42,920 --> 02:35:45,560
THAN ANOTHER BUT SAY CAN WE USE

3927
02:35:45,560 --> 02:35:48,160
THE INTERVENTION AS A PROBE TO

3928
02:35:48,160 --> 02:35:50,040
SEE WHICH SPECIFIC PATIENT

3929
02:35:50,040 --> 02:35:51,240
RESPONDS TO THAT INTERVENTION?

3930
02:35:51,240 --> 02:35:53,320
AND THEN GO BACK TO THE ANATOMY

3931
02:35:53,320 --> 02:35:54,920
AND BIOMARKERS AND SAY, OH,

3932
02:35:54,920 --> 02:35:56,920
WELL, ALL THE PEOPLE THAT

3933
02:35:56,920 --> 02:35:59,320
RESPONDED WELL TO, SAY,

3934
02:35:59,320 --> 02:36:00,840
ACUPRESSURE, THEY ALL HAD THIS

3935
02:36:00,840 --> 02:36:03,800
TYPE OF PHENOTYPE BASED ON THEIR

3936
02:36:03,800 --> 02:36:07,160
BRAIN STRUCTURE OR THEIR

3937
02:36:07,160 --> 02:36:11,960
BIOPSIES OR GENETICS OR

3938
02:36:11,960 --> 02:36:15,400
PROTEOMICS, ET CETERA, A WAY TO

3939
02:36:15,400 --> 02:36:17,400
FAST TRACK RATHER THAN BUILDING

3940
02:36:17,400 --> 02:36:18,960
FROM FOUNDATION UP, FROM ANATOMY

3941
02:36:18,960 --> 02:36:22,360
UP, TO GO TO TREATMENTS, AND

3942
02:36:22,360 --> 02:36:23,880
GIVE US INFORMATION GOING

3943
02:36:23,880 --> 02:36:24,240
BACKWARDS.

3944
02:36:24,240 --> 02:36:25,720
I THINK THAT APPROACH OF GOING

3945
02:36:25,720 --> 02:36:28,040
FORWARD AND BACKWARD AT THE SAME

3946
02:36:28,040 --> 02:36:30,360
TIME I THINK IS REALLY

3947
02:36:30,360 --> 02:36:31,160
REMARKABLE FOR BACPAC AND I'M

3948
02:36:31,160 --> 02:36:35,000
HAPPY TO BE PART OF THAT STUDY,

3949
02:36:35,000 --> 02:36:41,120
LOVE WORKING AT U OF M WITH DR.

3950
02:36:41,120 --> 02:36:41,320
KLAW.

3951
02:36:41,320 --> 02:36:43,360
THOUGHT I WOULD MAKE THAT PLUG.

3952
02:36:43,360 --> 02:36:46,120
>> I DON'T SEE US DOING

3953
02:36:46,120 --> 02:36:47,600
METABOLOMICS UNLESS IT'S REALLY

3954
02:36:47,600 --> 02:36:49,240
EASY, QUICK AND CHEAP, CERTAINLY

3955
02:36:49,240 --> 02:36:50,560
NOT BRAIN IMAGING AT THIS POINT

3956
02:36:50,560 --> 02:36:54,360
IN TIME IN THE CLINIC FOR

3957
02:36:54,360 --> 02:36:55,160
ORDINARY PATIENTS.

3958
02:36:55,160 --> 02:36:56,440
SO, I PRESUME THAT ONCE YOU'VE

3959
02:36:56,440 --> 02:36:59,840
DONE THAT YOU'LL NEED SOME SORT

3960
02:36:59,840 --> 02:37:00,800
OF BIOMARKERS THAT ARE MUCH

3961
02:37:00,800 --> 02:37:03,560
EASIER THAT GIVE YOU A HINT OF

3962
02:37:03,560 --> 02:37:06,280
WHAT YOU WOULD FIND IF YOU DID

3963
02:37:06,280 --> 02:37:07,800
THESE MORE EXTENSIVE AND

3964
02:37:07,800 --> 02:37:08,200
EXPENSIVE STUDIES.

3965
02:37:08,200 --> 02:37:11,480
>> YEAH, I DON'T KNOW ABOUT

3966
02:37:11,480 --> 02:37:13,000
BRAIN IMAGING PER SE BECAUSE THE

3967
02:37:13,000 --> 02:37:14,120
FIELD MOVES QUICKLY, WHAT WE'RE

3968
02:37:14,120 --> 02:37:16,160
DOING IN THE SCANNERS COULD BE

3969
02:37:16,160 --> 02:37:21,120
CLINICALLY  RELEVANT IN A COUPLE

3970
02:37:21,120 --> 02:37:21,320
YEARS.

3971
02:37:21,320 --> 02:37:23,720
I FEEL LIKE BRAIN IMAGING A

3972
02:37:23,720 --> 02:37:25,960
MIGHT BE ABLE TO BE CLINICALLY

3973
02:37:25,960 --> 02:37:26,280
MEANINGFUL.

3974
02:37:26,280 --> 02:37:28,960
WE PUT PEOPLE IN SCANNERS FOR

3975
02:37:28,960 --> 02:37:30,280
ALL SORTS OF THINGS, AND WE DO

3976
02:37:30,280 --> 02:37:33,040
IT FOR ALL SORTS OF OTHER

3977
02:37:33,040 --> 02:37:33,360
CONDITIONS.

3978
02:37:33,360 --> 02:37:36,760
SO, WHY COULDN'T WE ALSO DO THE

3979
02:37:36,760 --> 02:37:37,960
BRAIN SCANNING FOR MECHANISM OF

3980
02:37:37,960 --> 02:37:40,040
PAIN WHICH IS A SENSORY

3981
02:37:40,040 --> 02:37:40,360
PHENOMENON?

3982
02:37:40,360 --> 02:37:43,160
>>  IN THE REAL WORLD, IT'S VERY

3983
02:37:43,160 --> 02:37:44,120
EXPENSIVE.

3984
02:37:44,120 --> 02:37:45,040
IN OUR HEALTH CARE SYSTEM AT

3985
02:37:45,040 --> 02:37:48,040
LEAST IT'S HARD TO GET IN AND

3986
02:37:48,040 --> 02:37:49,320
THAT KIND OF THING.

3987
02:37:49,320 --> 02:37:52,040
YOU KNOW, I DON'T SEE THIS MAYBE

3988
02:37:52,040 --> 02:37:53,360
BEING SOMETHING AVAILABLE,

3989
02:37:53,360 --> 02:37:54,000
FEDERALLY QUALIFIED HEALTH

3990
02:37:54,000 --> 02:37:56,520
CENTERS OR OTHER THINGS LIKE

3991
02:37:56,520 --> 02:37:57,680
THAT.

3992
02:37:57,680 --> 02:38:00,240
I THINK THERE ARE SOME PRACTICAL

3993
02:38:00,240 --> 02:38:00,480
ASPECTS.

3994
02:38:00,480 --> 02:38:01,680
MAYBE THE SCANNERS WILL BE THE

3995
02:38:01,680 --> 02:38:04,120
SORT OF THING THAT DOCTORS HAVE

3996
02:38:04,120 --> 02:38:05,400
IN THEIR OFFICES SOMEDAY.

3997
02:38:05,400 --> 02:38:06,560
>> YOU KNOW, I WISH I COULD

3998
02:38:06,560 --> 02:38:10,680
RECALL MORE OF THE DETAILS BUT I

3999
02:38:10,680 --> 02:38:11,880
PARTICIPATED IN A REALLY

4000
02:38:11,880 --> 02:38:15,280
INTERESTING CONVERSATION RELATED

4001
02:38:15,280 --> 02:38:16,360
TO BACPAC WHERE STAKEHOLDERS,

4002
02:38:16,360 --> 02:38:17,880
NOT JUST THOSE WHO MAKE

4003
02:38:17,880 --> 02:38:21,280
DECISIONS ABOUT WHAT CAN ARE

4004
02:38:21,280 --> 02:38:23,160
COVERED, ARE WEIGHING IN EARLY

4005
02:38:23,160 --> 02:38:24,120
ON.

4006
02:38:24,120 --> 02:38:25,120
YES, IMAGING IS EXPENSIVE, BUT

4007
02:38:25,120 --> 02:38:27,720
WHEN YOU CONSIDER THE TOTALITY

4008
02:38:27,720 --> 02:38:31,360
OF COST, YOU KNOW, IN MANY

4009
02:38:31,360 --> 02:38:33,960
DIMENSIONS FOR FAILED AND

4010
02:38:33,960 --> 02:38:34,640
INADEQUATE TREATMENT OF CHRONIC

4011
02:38:34,640 --> 02:38:37,600
CONDITIONS, YOU KNOW, IT MIGHT

4012
02:38:37,600 --> 02:38:40,640
MAKE SENSE TO, YOU KNOW, INVEST

4013
02:38:40,640 --> 02:38:42,160
IN SOME EXPENSEIVE PHENOTYPING

4014
02:38:42,160 --> 02:38:43,600
UP FRONT BECAUSE OF THE SAVINGS

4015
02:38:43,600 --> 02:38:45,520
IN TERMS OF DOLLARS AND OUTCOMES

4016
02:38:45,520 --> 02:38:47,760
AND STUFF, ET CETERA.

4017
02:38:47,760 --> 02:38:49,760
I WAS PLEASED THAT THAT

4018
02:38:49,760 --> 02:38:52,360
PERSPECTIVE OF FOLKS WHO WOULD

4019
02:38:52,360 --> 02:38:54,400
BE INVOLVED IN ULTIMATELY

4020
02:38:54,400 --> 02:38:56,200
APPROVING USE OF THESE SORTS OF

4021
02:38:56,200 --> 02:38:57,520
THINGS IN DIFFERENT CLINICAL

4022
02:38:57,520 --> 02:39:00,320
SETTINGS WERE BEING BROUGHT INTO

4023
02:39:00,320 --> 02:39:00,920
THE BACPAC CONVERSATION EARLY

4024
02:39:00,920 --> 02:39:02,760
RATHER THAN LATER.

4025
02:39:02,760 --> 02:39:08,720
IT WAS A REALLY GOOD STRATEGY.

4026
02:39:08,720 --> 02:39:09,000
>> RIGHT.

4027
02:39:09,000 --> 02:39:12,000
THAT'S ONE OF THE REASONS I

4028
02:39:12,000 --> 02:39:13,760
THINK FROM THE MYOFASCIAL PAIN

4029
02:39:13,760 --> 02:39:16,040
INITIATIVE ONE OF THE HYPOTHESES

4030
02:39:16,040 --> 02:39:21,160
BEHIND THIS WHOLE THING IS THAT

4031
02:39:21,160 --> 02:39:22,280
NOBODY HAS REALLY IMAGED THOSE

4032
02:39:22,280 --> 02:39:24,480
TISSUES BEFORE.

4033
02:39:24,480 --> 02:39:29,600
WE DON'T HAVE MEASUREMENTS TO

4034
02:39:29,600 --> 02:39:31,840
LOOK AT MUSCLES, CONNECTIVE

4035
02:39:31,840 --> 02:39:32,600
TISSUE, AND FASCIA TOGETHER.

4036
02:39:32,600 --> 02:39:35,360
ONE OF THE REASONS PEOPLE SAY

4037
02:39:35,360 --> 02:39:36,760
IMAGING IS TOO EXPENSIVE,

4038
02:39:36,760 --> 02:39:39,840
DOESN'T CORRELATE WITH ANYTHING,

4039
02:39:39,840 --> 02:39:43,160
WELL, YOU KNOW, WE MAY HAVE TO

4040
02:39:43,160 --> 02:39:44,240
HUNT AROUND, KEEP GOING UNTIL

4041
02:39:44,240 --> 02:39:46,240
YOU FIND THE RIGHT THING TO LOOK

4042
02:39:46,240 --> 02:39:46,520
AT.

4043
02:39:46,520 --> 02:39:47,560
YOU HAVEN'T NECESSARILY LOOKED

4044
02:39:47,560 --> 02:39:49,200
AT EVERYTHING YET.

4045
02:39:49,200 --> 02:39:50,560
WE SHOULDN'T GET DISCOURAGED

4046
02:39:50,560 --> 02:39:51,760
JUST BECAUSE, YOU KNOW, WE

4047
02:39:51,760 --> 02:39:53,240
HAVEN'T DONE IT YET.

4048
02:39:53,240 --> 02:39:55,440
I WOULD SAY IT'S REALLY

4049
02:39:55,440 --> 02:39:58,720
IMPORTANT TO THINK ABOUT THE

4050
02:39:58,720 --> 02:40:02,120
KINDS OF PHENOTYPING THAT WE ARE

4051
02:40:02,120 --> 02:40:03,360
MISSING.

4052
02:40:03,360 --> 02:40:05,360
WHAT ARE THE GAPS IN OUR WAYS TO

4053
02:40:05,360 --> 02:40:08,040
THINK ABOUT THE BODY, TO LOOK AT

4054
02:40:08,040 --> 02:40:09,040
IT, TO MEASURE IT?

4055
02:40:09,040 --> 02:40:15,360
WE STILL HAVE A LOT TO LEARN.

4056
02:40:15,360 --> 02:40:17,920
>> WE MAY BE ABLE TO IDENTIFY

4057
02:40:17,920 --> 02:40:20,760
CORRELATES OF MORE EXPENSIVE AND

4058
02:40:20,760 --> 02:40:23,480
INTENSIVE PHENOTYPING TOO THAT

4059
02:40:23,480 --> 02:40:25,560
WOULD BE OBVIOUSLY GREAT

4060
02:40:25,560 --> 02:40:26,320
UTILITY.

4061
02:40:26,320 --> 02:40:26,960
>> EXACTLY.

4062
02:40:26,960 --> 02:40:29,160
SOMETHING AS SIMPLE AS

4063
02:40:29,160 --> 02:40:30,160
PALPATION, RIGHT?

4064
02:40:30,160 --> 02:40:34,320
YOU KNOW, YOU LOOK AT A SKILLED

4065
02:40:34,320 --> 02:40:36,480
MANUAL THERAPIST, THEY FEEL

4066
02:40:36,480 --> 02:40:38,000
THINGS WITH THEIR HANDS THAT WE

4067
02:40:38,000 --> 02:40:42,600
KNOW WHAT THEY ARE FEELING BUT

4068
02:40:42,600 --> 02:40:44,360
THERE'S NO OBJECTIVE MEASUREMENT

4069
02:40:44,360 --> 02:40:45,680
CORRELATED WE DON'T HAVE GOOD

4070
02:40:45,680 --> 02:40:48,360
WAYS TO IMPLEMENT OR ACT ON IT

4071
02:40:48,360 --> 02:40:49,520
THAT IS SCIENTIFIC, RIGHT?

4072
02:40:49,520 --> 02:40:51,120
BUT ONCE YOU HAVE THAT, THEN YOU

4073
02:40:51,120 --> 02:40:54,360
CAN GO BACK TO THE PALPATION

4074
02:40:54,360 --> 02:40:58,240
AND, YOU KNOW, IT'S VERY CHEAP

4075
02:40:58,240 --> 02:40:59,520
TO PALPATE.

4076
02:40:59,520 --> 02:41:02,080
YOU ABOUT IF YOU HAD WAYS YOU

4077
02:41:02,080 --> 02:41:05,360
COULD USE THE ULTRASOUND OR MRI,

4078
02:41:05,360 --> 02:41:06,960
WHATEVER, UNDERSTAND WHAT IT IS

4079
02:41:06,960 --> 02:41:09,840
YOU'RE PALPATING THEN I THINK IT

4080
02:41:09,840 --> 02:41:12,920
WOULD START TO GO BACK, FIND

4081
02:41:12,920 --> 02:41:15,240
CHEAPER WAYS TO -- YEAH.

4082
02:41:15,240 --> 02:41:17,080
>> WE'VE EXPERIMENTED WITH THAT.

4083
02:41:17,080 --> 02:41:21,200
OH, I'M SORRY.

4084
02:41:21,200 --> 02:41:23,520
>> I'M SORRY.

4085
02:41:23,520 --> 02:41:25,720
>> THERE'S A DEVICE CALLED

4086
02:41:25,720 --> 02:41:26,360
BUTTERFLY ULTRASOUND, I DON'T

4087
02:41:26,360 --> 02:41:29,080
KNOW IF ANYBODY HEARD OF THIS.

4088
02:41:29,080 --> 02:41:30,960
ULTRASOUND PROBE THAT PLUGS INTO

4089
02:41:30,960 --> 02:41:31,520
YOUR PHONE.

4090
02:41:31,520 --> 02:41:33,240
DOWNLOADED APP AND YOU CAN LOOK

4091
02:41:33,240 --> 02:41:33,800
AT IT.

4092
02:41:33,800 --> 02:41:36,640
SO WE'VE PLAYED AROUND WITH

4093
02:41:36,640 --> 02:41:40,160
THOSE IN OUR LABS FOR FIRST-YEAR

4094
02:41:40,160 --> 02:41:49,200
STUDENTS LOOKING AT ACHROMIUM 

4095
02:41:49,200 --> 02:41:50,840
PROCESS, GREATER TUBEROSITY AND

4096
02:41:50,840 --> 02:41:52,480
SEE THEIR FINGER COMING DOWN ON

4097
02:41:52,480 --> 02:41:54,760
THE DEVICE.

4098
02:41:54,760 --> 02:41:55,960
UNFORTUNATELY INCREDIBLY TIME

4099
02:41:55,960 --> 02:41:58,440
CONSUMING BUT RESULTS IN A LOT

4100
02:41:58,440 --> 02:41:59,560
OF LIGHT BULB MOMENTS.

4101
02:41:59,560 --> 02:42:08,720
I'M ACTUALLY ON THE THING.

4102
02:42:08,720 --> 02:42:09,360
COMPLICATED STRUCTURES, IT'S

4103
02:42:09,360 --> 02:42:10,840
HARDER TO DO THAT BUT WE'VE

4104
02:42:10,840 --> 02:42:14,120
EXPERIMENTED AND IT DOES SEEM TO

4105
02:42:14,120 --> 02:42:14,680
GREATLY INCREASE STUDENTS'

4106
02:42:14,680 --> 02:42:15,360
CONFIDENCE THAT THEY ARE ON WHAT

4107
02:42:15,360 --> 02:42:23,920
THEY THINK THEY ARE ON.

4108
02:42:23,920 --> 02:42:27,000
>> I JUST WANT TO SAY SOMETHING,

4109
02:42:27,000 --> 02:42:29,760
ADD SOMETHING SIMILAR.

4110
02:42:29,760 --> 02:42:33,280
PALPATION IS A SKILL THAT IS

4111
02:42:33,280 --> 02:42:35,000
NEGLECTED IN OUR MEDICAL SCHOOLS

4112
02:42:35,000 --> 02:42:36,640
COMPARED TO ULTRASOUND AND

4113
02:42:36,640 --> 02:42:39,360
IMAGING STUDIES.

4114
02:42:39,360 --> 02:42:43,680
SO I WANT TO GO BACK TO THE

4115
02:42:43,680 --> 02:42:47,480
SUGGESTION, EDUCATION IS 

4116
02:42:47,480 --> 02:42:51,200
IMPORTANT. 

4117
02:42:51,200 --> 02:42:58,200
HANDS-ON EDUCATION WITH 

4118
02:42:58,200 --> 02:42:58,600
PALPATION.

4119
02:42:58,600 --> 02:43:00,680
>> DR. DELITTO?

4120
02:43:00,680 --> 02:43:02,640
>> I'LL TRY NOT TO BE

4121
02:43:02,640 --> 02:43:03,200
CONTROVERSIAL.

4122
02:43:03,200 --> 02:43:09,760
I DON'T SEE PALPATION COMING 

4123
02:43:09,760 --> 02:43:11,480
BACK TO MEDICAL SCHOOLS.

4124
02:43:11,480 --> 02:43:12,360
IN STUDIES WE'VE DONE, YOU KNOW,

4125
02:43:12,360 --> 02:43:14,560
ONCE YOU GET INTO THE PRAGMATIC

4126
02:43:14,560 --> 02:43:16,520
NATURE OF TRIALS AND TRY TO GET

4127
02:43:16,520 --> 02:43:20,120
PRIMARY PHYSICIANS TO TOUCH A

4128
02:43:20,120 --> 02:43:22,360
PATIENT, WITHOUT A STETHOSCOPE,

4129
02:43:22,360 --> 02:43:25,280
IT'S PRETTY DIFFICULT.

4130
02:43:25,280 --> 02:43:27,480
SOME OF OUR STUDIES WITH KNEE

4131
02:43:27,480 --> 02:43:31,040
O.A., FOR EXAMPLE, YOU KNOW,

4132
02:43:31,040 --> 02:43:34,920
JUST THE CLINICAL DIAGNOSIS OF

4133
02:43:34,920 --> 02:43:35,880
OSTEOARTHRITIS REQUIRES

4134
02:43:35,880 --> 02:43:37,160
PALPATION FOR PAIN OF THE KNEE,

4135
02:43:37,160 --> 02:43:39,400
AND WE COULDN'T GET PRIMARY CARE

4136
02:43:39,400 --> 02:43:41,720
PHYSICIANS TO DO THAT.

4137
02:43:41,720 --> 02:43:44,160
SO I DON'T KNOW, I THINK IT'S A

4138
02:43:44,160 --> 02:43:47,040
LOST ART, YOU KNOW, WITH REGARD

4139
02:43:47,040 --> 02:43:47,920
TO PHYSICIANS.

4140
02:43:47,920 --> 02:43:51,960
BUT IT'S WHAT WE DO IN MOST OF

4141
02:43:51,960 --> 02:43:57,200
OUR OTHER PROFESSIONS.

4142
02:43:57,200 --> 02:43:58,640
P.T., CHIRO, ALL OF THEM.

4143
02:43:58,640 --> 02:44:05,760
I'M  WONDERING IF WE SET THE BAR

4144
02:44:05,760 --> 02:44:07,320
 HIGH TRYING TO OBJECTIFY,

4145
02:44:07,320 --> 02:44:09,480
GETTING TO POINT WHEN ARE WE

4146
02:44:09,480 --> 02:44:10,360
READY FOR COMPARATIVE

4147
02:44:10,360 --> 02:44:11,440
EFFECTIVENESS TRIAL?

4148
02:44:11,440 --> 02:44:12,760
EVERYBODY WANTS TO GET THE

4149
02:44:12,760 --> 02:44:16,120
INTERVENTION DOWN, WANTS TO HAVE

4150
02:44:16,120 --> 02:44:18,760
THE INTERVENTION SOLELY BASED ON

4151
02:44:18,760 --> 02:44:19,640
SOME BASIC WORK, MECHANISTIC

4152
02:44:19,640 --> 02:44:23,000
WORK, BUT THAT'S NOT WHAT WE'RE

4153
02:44:23,000 --> 02:44:24,880
GOING UP AGAINST.

4154
02:44:24,880 --> 02:44:27,040
I HAVEN'T SEEN THE SURGERY, AND

4155
02:44:27,040 --> 02:44:27,760
SO FORTH.

4156
02:44:27,760 --> 02:44:30,160
THEY HAVE NOT BEEN SUBJECTED TO

4157
02:44:30,160 --> 02:44:31,760
THAT LEVEL OF SCRUTINY.

4158
02:44:31,760 --> 02:44:34,520
AND EVERY DAY PEOPLE ARE GETTING

4159
02:44:34,520 --> 02:44:35,800
UNNECESSARY PROCEDURES DONE TO

4160
02:44:35,800 --> 02:44:36,240
THEM.

4161
02:44:36,240 --> 02:44:40,840
I JUST KEEP REMINDING PEOPLE OF

4162
02:44:40,840 --> 02:44:42,280
THAT.

4163
02:44:42,280 --> 02:44:43,480
AND UNNECESSARY PROCEDURES,

4164
02:44:43,480 --> 02:44:46,320
WELL, IT'S ALMOST -- SOMETIMES

4165
02:44:46,320 --> 02:44:48,520
IT'S ALMOST "60 MINUTES"

4166
02:44:48,520 --> 02:44:49,120
MATERIAL.

4167
02:44:49,120 --> 02:44:51,720
I'M THROWING ALL THAT OUT.

4168
02:44:51,720 --> 02:44:57,160
>> YOU WERE SUCCESSFUL IN BEING

4169
02:44:57,160 --> 02:44:59,240
PROVOCATIVE, TONY.

4170
02:44:59,240 --> 02:45:02,760
NOW FOUR PEOPLE HAVE COMMENTS.

4171
02:45:02,760 --> 02:45:05,240
>> WHAT'S OUR STOP TIME TO MAKE

4172
02:45:05,240 --> 02:45:09,360
SURE EMMELINE HAS TIME TO GIVE

4173
02:45:09,360 --> 02:45:09,960
HER PRESENTATION?

4174
02:45:09,960 --> 02:45:12,920
>>  WE'VE STILL GOT ANOTHER 20

4175
02:45:12,920 --> 02:45:13,960
MINUTES.

4176
02:45:13,960 --> 02:45:14,320
>> OKAY.

4177
02:45:14,320 --> 02:45:15,040
THANKS.

4178
02:45:15,040 --> 02:45:15,560
>> EXCELLENT.

4179
02:45:15,560 --> 02:45:18,160
I WON'T TAKE ALL THAT.

4180
02:45:18,160 --> 02:45:21,760
I AGREE WITH YOUR STATEMENTS

4181
02:45:21,760 --> 02:45:25,680
THAT A LOT OF PHYSICIANS ARE NOT

4182
02:45:25,680 --> 02:45:26,560
TRAINED TO TOUCH.

4183
02:45:26,560 --> 02:45:30,360
I THINK THIS IS, AGAIN, ANOTHER

4184
02:45:30,360 --> 02:45:31,000
PLACE THAT OSTEOPATHIC

4185
02:45:31,000 --> 02:45:33,560
PHYSICIANS SHOULD BE REALLY

4186
02:45:33,560 --> 02:45:35,840
BROUGHT IN AND WE CAN SHINE

4187
02:45:35,840 --> 02:45:39,080
BECAUSE FROM THE FIRST WEEK OF

4188
02:45:39,080 --> 02:45:40,240
OSTEOPATHIC MEDICAL SCHOOL, OUR

4189
02:45:40,240 --> 02:45:44,360
STUDENTS ARE TRAINED TO TOUCH.

4190
02:45:44,360 --> 02:45:45,960
AND INCORPORATING ORTHOPEDIC

4191
02:45:45,960 --> 02:45:48,440
EXAM INTO AN OSTEOPATHIC

4192
02:45:48,440 --> 02:45:49,640
STRUCTURAL EXAM IS WHAT THEY ARE

4193
02:45:49,640 --> 02:45:52,520
TRAINED TO DO AND WHAT THEY ARE

4194
02:45:52,520 --> 02:45:55,160
TESTED ON DOING, AND WHAT WE --

4195
02:45:55,160 --> 02:45:59,040
THE FEEDBACK WE GET FROM 

4196
02:45:59,040 --> 02:46:03,120
RESIDENCIES THAT OUR STUDENTS DO

4197
02:46:03,120 --> 02:46:04,800
IN PRACTICE PRESENT DIFFERENTLY

4198
02:46:04,800 --> 02:46:06,480
BECAUSE THEY DON'T HAVE THAT

4199
02:46:06,480 --> 02:46:07,520
FEAR OF TOUCH, BECAUSE THEY HAVE

4200
02:46:07,520 --> 02:46:11,760
LEARNED HOW TO USE THEIR HANDS.

4201
02:46:11,760 --> 02:46:15,480
AND I UNDERSTAND THAT IN A LOT

4202
02:46:15,480 --> 02:46:17,160
OF WAYS IT'S LESS VALIDATED THAN

4203
02:46:17,160 --> 02:46:20,240
SOME IMAGING TECHNIQUES AND SOME

4204
02:46:20,240 --> 02:46:22,840
OTHER SORT OF STUDY TECHNIQUES

4205
02:46:22,840 --> 02:46:25,160
BUT THERE'S A LOT OF OUR PATIENT

4206
02:46:25,160 --> 02:46:27,200
POPULATION IN THIS COUNTRY THAT

4207
02:46:27,200 --> 02:46:29,200
DON'T HAVE ACCESS TO THOSE

4208
02:46:29,200 --> 02:46:32,920
ADVANCED IMAGING TECHNIQUES OR

4209
02:46:32,920 --> 02:46:33,880
CAN'T AFFORD IT.

4210
02:46:33,880 --> 02:46:34,760
THAT'S WHERE TEACHING A

4211
02:46:34,760 --> 02:46:37,760
PHYSICIAN AT THE POINT OF CARE

4212
02:46:37,760 --> 02:46:40,360
HOW TO PALPATE RELIABLY TO WHAT

4213
02:46:40,360 --> 02:46:43,960
DEGREE WE CAN AND MAKING A

4214
02:46:43,960 --> 02:46:46,240
DIFFERENCE AT THAT POINT IS

4215
02:46:46,240 --> 02:46:48,120
CRUCIAL, AS WE CONTINUE TO GROW

4216
02:46:48,120 --> 02:46:52,560
OUR AGING POPULATION AND HAVE

4217
02:46:52,560 --> 02:46:53,840
MORE AND MORE MUSCULOSKELETAL

4218
02:46:53,840 --> 02:46:54,080
ISSUES.

4219
02:46:54,080 --> 02:46:55,920
THIS IS WITHIN THE NEXT FOUR OR

4220
02:46:55,920 --> 02:46:57,960
FIVE YEARS D.O.s WILL BE ONE

4221
02:46:57,960 --> 02:47:02,240
IN TEN OF THE PHYSICIANS IN THIS

4222
02:47:02,240 --> 02:47:02,560
COUNTRY.

4223
02:47:02,560 --> 02:47:04,200
WE HAVE A HUGE AND GROWING

4224
02:47:04,200 --> 02:47:05,520
POPULATION OF PHYSICIANS THAT

4225
02:47:05,520 --> 02:47:07,880
ARE TRAINED HOW TO DO THEIR

4226
02:47:07,880 --> 02:47:09,120
HANDS, HOW TO USE THEIR HANDS.

4227
02:47:09,120 --> 02:47:11,880
AND SO PERHAPS WE NEED TO BE

4228
02:47:11,880 --> 02:47:17,760
LOOPING THAT IN THE CONVERSATION

4229
02:47:17,760 --> 02:47:19,360
A BIT MORE.

4230
02:47:19,360 --> 02:47:22,040
THERE'S SEVERAL ORGANIZATIONS

4231
02:47:22,040 --> 02:47:26,000
THAT TEACH COURSES ON PALPATORY

4232
02:47:26,000 --> 02:47:26,560
DIAGNOSIS AND PALPATORY

4233
02:47:26,560 --> 02:47:28,960
TREATMENT THAT ARE OPEN TO

4234
02:47:28,960 --> 02:47:32,760
P.A.s, NPS, M.D.s, PTs, ET

4235
02:47:32,760 --> 02:47:34,320
CETERA, NOT THAT PTs -- THEY

4236
02:47:34,320 --> 02:47:38,120
ARE USUALLY PRETTY GOOD AT THAT

4237
02:47:38,120 --> 02:47:41,200
ANYWAY, BUT WE'RE ANXIOUS TO

4238
02:47:41,200 --> 02:47:44,360
TEACH AND -- I'LL STOP THERE.

4239
02:47:44,360 --> 02:47:46,640
>> THANK YOU.

4240
02:47:46,640 --> 02:47:47,200
DR. HARRIS?

4241
02:47:47,200 --> 02:47:52,680
>>  I'LL JOIN IN AND STRESS THAT

4242
02:47:52,680 --> 02:47:53,560
TOUCH IS CRITICAL.

4243
02:47:53,560 --> 02:47:55,200
WHAT KIND OF PROFESSION ARE WE

4244
02:47:55,200 --> 02:47:59,400
IF WE'RE HEALERS AND WE'RE  NOT

4245
02:47:59,400 --> 02:48:00,760
TOUCHING, WE DON'T WANT TO TOUCH

4246
02:48:00,760 --> 02:48:01,560
OUR PATIENTS?

4247
02:48:01,560 --> 02:48:04,040
THAT SETS UP A DYNAMIC THAT GOES

4248
02:48:04,040 --> 02:48:08,360
COUNTER TO THE HEALING PROCESS.

4249
02:48:08,360 --> 02:48:10,160
AS AN ACUPUNCTURIST, I LEARNED

4250
02:48:10,160 --> 02:48:14,760
TO DO ACUPRESSURE WITH  MY HANDS

4251
02:48:14,760 --> 02:48:15,880
AND FINGERS.

4252
02:48:15,880 --> 02:48:19,880
I SEE PATIENTS, AFTER NEEDLING

4253
02:48:19,880 --> 02:48:21,520
I'LL DO ACUPRESSURE, THAT

4254
02:48:21,520 --> 02:48:23,160
PROVIDES A CONNECTION.

4255
02:48:23,160 --> 02:48:24,120
I THINK IT'S SO IMPORTANT.

4256
02:48:24,120 --> 02:48:26,680
ONE OF THE THINGS I WAS THINKING

4257
02:48:26,680 --> 02:48:29,080
ABOUT IN TERMS OF WHAT HELENE

4258
02:48:29,080 --> 02:48:30,800
WAS TALKING ABOUT, JOINTS AND

4259
02:48:30,800 --> 02:48:31,760
MYOFASCIAL TISSUES AND

4260
02:48:31,760 --> 02:48:34,560
EVERYTHING, SOMETHING THAT

4261
02:48:34,560 --> 02:48:37,560
HASN'T REALLY BEEN LOOKED AT

4262
02:48:37,560 --> 02:48:43,160
FROM THE RESEARCH PERSPECTIVE IS

4263
02:48:43,160 --> 02:48:50,080
GUASA AS A FORM OF HEALING.

4264
02:48:50,080 --> 02:48:53,840
THE TOUCH IN THAT PROCEDURE

4265
02:48:53,840 --> 02:48:56,120
COULD BE STUDIED.

4266
02:48:56,120 --> 02:49:01,120
I'LL PUT A PLUG IN FOR NOTICE OF

4267
02:49:01,120 --> 02:49:03,840
INTENT OR SOME INTEREST IN

4268
02:49:03,840 --> 02:49:09,000
CUPPING AND GUASA AS ADDITIONAL

4269
02:49:09,000 --> 02:49:10,520
TOUCH THERAPIES THAT GET AT THE

4270
02:49:10,520 --> 02:49:11,440
MYOFASCIAL TISSUE.

4271
02:49:11,440 --> 02:49:16,400
>> I RECENTLY SAW A PICTURE OF,

4272
02:49:16,400 --> 02:49:18,480
ULTRASOUND PICTURE WHERE YOU PUT

4273
02:49:18,480 --> 02:49:22,640
THE CUP, SUCTION, TWO LAYERS OF

4274
02:49:22,640 --> 02:49:25,280
FASCIA THAT WERE ADHERENT BECAME

4275
02:49:25,280 --> 02:49:25,760
SEPARATED.

4276
02:49:25,760 --> 02:49:27,480
I DIDN'T THINK THAT CUPPING

4277
02:49:27,480 --> 02:49:28,560
COULD DO THAT.

4278
02:49:28,560 --> 02:49:31,840
I SAW IT WITH ULTRASOUND, VERY

4279
02:49:31,840 --> 02:49:33,640
INTERESTING TO SEE.

4280
02:49:33,640 --> 02:49:34,680
>> WE NEED MORE RESEARCH.

4281
02:49:34,680 --> 02:49:36,440
>> WE DO.

4282
02:49:36,440 --> 02:49:42,880
I AGREE, YEAH. 

4283
02:49:42,880 --> 02:49:43,440
LET'S SEE.

4284
02:49:43,440 --> 02:49:45,600
>> HI. 

4285
02:49:45,600 --> 02:49:50,880
I HAVE A POSITIVE COMMENT AND

4286
02:49:50,880 --> 02:49:52,720
ECHO TONY'S CAUTIONARY TALE.

4287
02:49:52,720 --> 02:49:55,880
I HAVE A DAUGHTER WHO IS A

4288
02:49:55,880 --> 02:49:57,960
THIRD, GOING INTO FOURTH YEAR AT

4289
02:49:57,960 --> 02:49:59,480
SINAI, AND IT'S ONE THING TO

4290
02:49:59,480 --> 02:50:03,120
TALK ABOUT TOUCH IN PRIMARY

4291
02:50:03,120 --> 02:50:04,360
CARE, TOUCH IN MEDICINE WHICH I

4292
02:50:04,360 --> 02:50:06,560
THINK IS NOT OUT OF FAVOR, THE

4293
02:50:06,560 --> 02:50:09,800
IDEA OF TOUCH OF COMMUNICATION,

4294
02:50:09,800 --> 02:50:10,920
WHETHER IT'S A HANDSHAKE OR

4295
02:50:10,920 --> 02:50:12,480
TAKING A PULSE OR WHATEVER.

4296
02:50:12,480 --> 02:50:19,000
BUT THE IDEA OF PHYSICIANS, NOT

4297
02:50:19,000 --> 02:50:20,000
OSTEOPATHIC, BEING TRAINED IN

4298
02:50:20,000 --> 02:50:22,600
WHICH THE LEVEL OF PALPATION

4299
02:50:22,600 --> 02:50:24,720
COULD BE DIAGNOSTIC, NOBODY

4300
02:50:24,720 --> 02:50:26,480
SHOULD PURSUE THAT ROAD UNLESS

4301
02:50:26,480 --> 02:50:28,040
THEY WANT TO BE BANGING THEIR

4302
02:50:28,040 --> 02:50:29,440
HEAD AGAINST THE WALL.

4303
02:50:29,440 --> 02:50:31,560
THEY ARE GETTING EQUIPPED WITH

4304
02:50:31,560 --> 02:50:32,720
HAND-HELD ULTRASOUNDS, IT'S WHAT

4305
02:50:32,720 --> 02:50:35,320
THEY WANT FOR DIAGNOSIS.

4306
02:50:35,320 --> 02:50:40,680
I WANT TO THROW IN THAT REALITY

4307
02:50:40,680 --> 02:50:45,000
CHECK IN RELATION TO ALLOPATHIC

4308
02:50:45,000 --> 02:50:45,920
MEDICAL STUDENTS.

4309
02:50:45,920 --> 02:50:50,960
I WANT TO ECHO WHAT RICK SAYS

4310
02:50:50,960 --> 02:50:52,040
AND EXPAND.

4311
02:50:52,040 --> 02:50:53,920
THE WHOLE DISCIPLINE OF

4312
02:50:53,920 --> 02:50:55,440
ACUPRESSURE AND WHAT'S HAPPENING

4313
02:50:55,440 --> 02:50:58,600
IN THE TISSUES WITH ACCUPRESSURE

4314
02:50:58,600 --> 02:50:59,720
IS ALSO UNDERSTUDIED, FROM OUR

4315
02:50:59,720 --> 02:51:02,040
POINT OF VIEW DURING THE

4316
02:51:02,040 --> 02:51:03,360
PANDEMIC WHERE WE PIVOTED FROM

4317
02:51:03,360 --> 02:51:05,480
LOTS AND LOTS AND LOTS OF

4318
02:51:05,480 --> 02:51:06,960
IN-PERSON TREATMENT TO LOTS AND

4319
02:51:06,960 --> 02:51:08,160
LOTS OF TEACHING PEOPLE

4320
02:51:08,160 --> 02:51:10,120
VIRTUALLY HOW TO DO ACCUPRESSURE

4321
02:51:10,120 --> 02:51:11,760
ON THEMSELVES, AND THE KIND OF

4322
02:51:11,760 --> 02:51:13,520
FEEDBACK WE'VE GOTTEN ABOUT

4323
02:51:13,520 --> 02:51:14,920
EFFECTIVENESS OF THAT TECHNIQUE

4324
02:51:14,920 --> 02:51:17,560
IN TERMS OF EXPANDING ACCESS TO

4325
02:51:17,560 --> 02:51:20,160
THE BENEFITS, SOME BENEFITS OF

4326
02:51:20,160 --> 02:51:22,080
ACUPUNCTURE I'D LIKE TO THROW IN

4327
02:51:22,080 --> 02:51:25,160
ACCUPRESSURE TECHNIQUES INTO THE

4328
02:51:25,160 --> 02:51:26,760
MIX OF WHAT'S HAPPENING WITH

4329
02:51:26,760 --> 02:51:30,720
MANUAL THERAPIES, THAT WOULD BE

4330
02:51:30,720 --> 02:51:30,960
FANTASTIC.

4331
02:51:30,960 --> 02:51:32,680
VERY RELEVANT.

4332
02:51:32,680 --> 02:51:38,360
>> THANK YOU.

4333
02:51:38,360 --> 02:51:41,120
DR. MEHLING?

4334
02:51:41,120 --> 02:51:42,080
YOU'RE ON MUTE.

4335
02:51:42,080 --> 02:51:43,400
>> ACCUPRESSURE POINTS AND

4336
02:51:43,400 --> 02:51:46,960
TRIGGER POINTS ARE OFTEN

4337
02:51:46,960 --> 02:51:49,640
OVERLAPPING, 50% THE SAME.

4338
02:51:49,640 --> 02:51:51,680
AT UCSF WE ACTUALLY HAVE FOR 14

4339
02:51:51,680 --> 02:51:55,560
YEARS TAUGHT ABOUT 10% OF

4340
02:51:55,560 --> 02:51:56,680
MEDICAL STUDENTS MASSAGE, AND

4341
02:51:56,680 --> 02:51:58,080
THEY LEARN HOW TO TOUCH TRIGGER

4342
02:51:58,080 --> 02:52:00,360
POINTS AND HOW TO FEEL IT.

4343
02:52:00,360 --> 02:52:04,560
IT'S A MINORITY, I TOTALLY

4344
02:52:04,560 --> 02:52:08,160
UNDERSTAND TONY'S FRUSTRATION

4345
02:52:08,160 --> 02:52:09,920
AND BEN'S, BUT INCREASING

4346
02:52:09,920 --> 02:52:11,040
INTEREST IN INTEGRATIVE MEDICINE

4347
02:52:11,040 --> 02:52:12,160
AMONG MEDICAL STUDENTS.

4348
02:52:12,160 --> 02:52:15,560
THEY WANT TO DO SOMETHING WITH

4349
02:52:15,560 --> 02:52:16,960
MASSAGE, FOR EXAMPLE.

4350
02:52:16,960 --> 02:52:25,160
AND SO IT'S ONE OF THE SOUGHT

4351
02:52:25,160 --> 02:52:26,120
AFTER ELECTIVES AT UCSF.

4352
02:52:26,120 --> 02:52:28,200
>> THANK YOU.

4353
02:52:28,200 --> 02:52:28,960
DR. SHERMAN?

4354
02:52:28,960 --> 02:52:30,960
>> JUST TO ADD SOME CONTEXT TO

4355
02:52:30,960 --> 02:52:33,040
THE PLUG FOR UNDERSTANDING SOME

4356
02:52:33,040 --> 02:52:54,760
OF THED ED E ADJUNCTIVE, WE ASK

4357
02:52:54,760 --> 02:52:56,880
ACUPUNCTURISTS AT EVERY VISIT IS

4358
02:52:56,880 --> 02:52:58,080
THERE SOMETHING YOU WISH YOU

4359
02:52:58,080 --> 02:52:59,520
COULD HAVE DONE AND THEY TELL US

4360
02:52:59,520 --> 02:53:04,240
FOR THE MOST PART, AND THEY WANT

4361
02:53:04,240 --> 02:53:05,720
TO DO ELECTRICAL STIMULATION.

4362
02:53:05,720 --> 02:53:08,120
MY QUESTION WOULD BE, OKAY, IF

4363
02:53:08,120 --> 02:53:09,960
WE KNOW WHAT ACUPUNCTURE NEEDLES

4364
02:53:09,960 --> 02:53:12,880
DO, WHAT HAPPENS WHEN YOU ADD

4365
02:53:12,880 --> 02:53:14,080
ELECTRICITY ON IT?

4366
02:53:14,080 --> 02:53:19,880
THEY WANT TO USE HEAT.

4367
02:53:19,880 --> 02:53:22,080
BOTH REGULAR AND MOXA, MAYBE

4368
02:53:22,080 --> 02:53:23,720
THERE ARE STUDIES THAT HAVE

4369
02:53:23,720 --> 02:53:25,200
SHOWN WHAT THAT CAN DO BUT IF

4370
02:53:25,200 --> 02:53:31,560
THERE AREN'T, THERE SHOULD BE.

4371
02:53:31,560 --> 02:53:35,360
CUPPING IS COMMON, LESS FOR

4372
02:53:35,360 --> 02:53:36,440
TUENA AND GUASHA, IT WOULD BE

4373
02:53:36,440 --> 02:53:37,640
FUN TO DO SOMEWHERE YOU FIGURE

4374
02:53:37,640 --> 02:53:39,400
OUT HOW TO MEASURE WHAT HAPPENS

4375
02:53:39,400 --> 02:53:42,920
WHEN YOU DO MULTIPLE OF THESE

4376
02:53:42,920 --> 02:53:43,320
THERAPIES.

4377
02:53:43,320 --> 02:53:46,960
JUST AGAIN TO PROVIDE A KIND OF

4378
02:53:46,960 --> 02:53:49,160
BIOLOGICAL BASIS FOR WHAT IT IS

4379
02:53:49,160 --> 02:53:53,160
THAT ACUPUNCTURISTS DO SO THAT

4380
02:53:53,160 --> 02:53:56,800
THESE FULL BODY TREATMENT CAN BE

4381
02:53:56,800 --> 02:53:57,040
STUDIED.

4382
02:53:57,040 --> 02:53:58,200
YOU KNOW, WE DON'T KNOW WHETHER

4383
02:53:58,200 --> 02:53:59,640
IT'S BETTER OR NOT BECAUSE NO

4384
02:53:59,640 --> 02:54:03,920
ONE HAS LOOKED AT IT.

4385
02:54:03,920 --> 02:54:08,160
>> THANK YOU,  DR. SHERMAN.

4386
02:54:08,160 --> 02:54:09,640
A HAND WENT UP AND DOWN.

4387
02:54:09,640 --> 02:54:11,720
DID YOU WANT TO MAKE A COMMENT?

4388
02:54:11,720 --> 02:54:14,240
>> NO, JUST GIVING A THUMBS UP

4389
02:54:14,240 --> 02:54:18,000
TO SOMEONE PREVIOUSLY. 

4390
02:54:18,000 --> 02:54:26,800
IT LOOKS THE SAME. 

4391
02:54:26,800 --> 02:54:29,000
>> I'M LEARNING A LOT FROM THIS

4392
02:54:29,000 --> 02:54:29,440
DISCUSSION.

4393
02:54:29,440 --> 02:54:31,000
I REALLY APPRECIATE THE

4394
02:54:31,000 --> 02:54:36,120
OPPORTUNITY TO STAY THROUGH THE

4395
02:54:36,120 --> 02:54:36,800
NEXT SESSION.

4396
02:54:36,800 --> 02:54:38,560
>> WE'RE SO GLAD YOU WERE ABLE

4397
02:54:38,560 --> 02:54:39,760
TO STAY.

4398
02:54:39,760 --> 02:54:43,440
AS YOU SEE, IT'S VERY RICH.

4399
02:54:43,440 --> 02:54:46,760
I'M REALLY, YOU KNOW, CURIOUS

4400
02:54:46,760 --> 02:54:52,000
ABOUT HOW FOLKS AT NIAMS, YOU 

4401
02:54:52,000 --> 02:54:58,360
KNOW, THINK ABOUT THINGS LIKE

4402
02:54:58,360 --> 02:54:59,320
MUSCULOSKELETAL PALPATION AND

4403
02:54:59,320 --> 02:55:03,480
OSTEOPATHIC TECHNIQUES AND

4404
02:55:03,480 --> 02:55:05,880
THINGS LIKE THAT.

4405
02:55:05,880 --> 02:55:09,800
IT'S INTERESTING TO SORT OF

4406
02:55:09,800 --> 02:55:11,120
THINK ACROSS OUR INSTITUTES

4407
02:55:11,120 --> 02:55:12,200
ABOUT QUESTIONS LIKE THAT.

4408
02:55:12,200 --> 02:55:26,640
IS THERE A WAY THESE CAN BE

4409
02:55:26,640 --> 02:55:26,960
TRANSLATABLE.

4410
02:55:26,960 --> 02:55:30,800
>> NEIGHBOR WE NEED A NIAMS AND

4411
02:55:30,800 --> 02:55:32,120
NICCH FOCUS GROUP.

4412
02:55:32,120 --> 02:55:35,400
>> A LOT OF WHAT WE ARE TALKING

4413
02:55:35,400 --> 02:55:36,960
ABOUT IN TERMS OF -- I MEAN OF

4414
02:55:36,960 --> 02:55:38,960
COURSE SO THIS IS THE

4415
02:55:38,960 --> 02:55:40,760
INTERESTING THING HERE, RIGHT?

4416
02:55:40,760 --> 02:55:43,040
FOR A LONG TIME, I WOULD SAY THE

4417
02:55:43,040 --> 02:55:46,720
LAST 20, 30 YEARS MAYBE, THE

4418
02:55:46,720 --> 02:55:51,040
PENDULUM HAS SWUNG IN THE DOMAIN

4419
02:55:51,040 --> 02:55:53,120
OF PAIN IT WENT INTO THE NERVOUS

4420
02:55:53,120 --> 02:55:55,280
SYSTEM, RIGHT?

4421
02:55:55,280 --> 02:55:56,600
IT STARTED IN PERIPHERAL TISSUES

4422
02:55:56,600 --> 02:56:00,960
IN THE '50s AND '60s, '70s

4423
02:56:00,960 --> 02:56:01,360
EVEN.

4424
02:56:01,360 --> 02:56:02,160
THEN SOMETHING HAPPENED, RIGHT?

4425
02:56:02,160 --> 02:56:04,040
ALL OF A SUDDEN PAIN JUST WENT

4426
02:56:04,040 --> 02:56:07,160
INTO THE BRAIN, JUST STAYED

4427
02:56:07,160 --> 02:56:07,640
THERE.

4428
02:56:07,640 --> 02:56:08,200
BRAIN, SPINAL CORD.

4429
02:56:08,200 --> 02:56:10,560
AND I THINK ONE OF THE THINGS

4430
02:56:10,560 --> 02:56:12,960
THAT WE WANT TO DO IS RECONNECT

4431
02:56:12,960 --> 02:56:14,920
THE BRAIN WITH THE REST OF THE

4432
02:56:14,920 --> 02:56:16,760
BODY IN TERMS OF PAIN

4433
02:56:16,760 --> 02:56:17,960
ESPECIALLY, ESPECIALLY WITH

4434
02:56:17,960 --> 02:56:18,680
MUSCULOSKELETAL PAIN.

4435
02:56:18,680 --> 02:56:21,400
I THINK THERE NEEDS TO BE ALL

4436
02:56:21,400 --> 02:56:26,000
THE EXPERTISE AND THAT'S WHY I'M

4437
02:56:26,000 --> 02:56:27,840
EXCITED ABOUT THIS RE-JOIN,

4438
02:56:27,840 --> 02:56:30,480
ESPECIALLY ABOUT THE INITIAL

4439
02:56:30,480 --> 02:56:36,160
MAPPING OF SENSORY NEURONS THAT

4440
02:56:36,160 --> 02:56:38,720
NIAMS IS LEADING BECAUSE -- IT'S

4441
02:56:38,720 --> 02:56:40,040
REALLY TAKING -- PUTTING IT BACK

4442
02:56:40,040 --> 02:56:43,080
WHERE IT NEEDS TO BE.

4443
02:56:43,080 --> 02:56:44,720
>> FIRST COMMENTS YOU MADE

4444
02:56:44,720 --> 02:56:45,720
DURING AN EARLY DISCUSSION, YOU

4445
02:56:45,720 --> 02:56:47,560
KNOW, I THOUGHT WAS REALLY

4446
02:56:47,560 --> 02:56:49,320
INTERESTING, HAS HELPED DRIVE

4447
02:56:49,320 --> 02:56:53,480
THIS WHOLE EFFORT, SO, YEAH,

4448
02:56:53,480 --> 02:56:55,560
REALLY INTERESTING OBSERVATION.

4449
02:56:55,560 --> 02:56:58,160
>> WE HAVE TWO MORE HANDS

4450
02:56:58,160 --> 02:56:58,680
RAISED.

4451
02:56:58,680 --> 02:57:00,720
DR. HARRIS AND DR. JEAN LOUIS.

4452
02:57:00,720 --> 02:57:02,120
>> I'LL CHIME IN QUICKLY.

4453
02:57:02,120 --> 02:57:04,840
SORRY TO TAKE UP TIME.

4454
02:57:04,840 --> 02:57:06,960
I DON'T THINK WE'RE GOING TO BE

4455
02:57:06,960 --> 02:57:08,560
DOING OURSELVES THE MOST FAVOR

4456
02:57:08,560 --> 02:57:12,760
WE CAN DO IF WE DESCRIBE THE

4457
02:57:12,760 --> 02:57:15,160
WHOLE PERSON WITHOUT HAVING

4458
02:57:15,160 --> 02:57:17,920
INTERVENTIONS THAT TARGET

4459
02:57:17,920 --> 02:57:20,000
MULTIPLE LEVELS AND MULTIPLE

4460
02:57:20,000 --> 02:57:21,760
AREAS, CONCURRENTLY, AT THE SAME

4461
02:57:21,760 --> 02:57:23,360
TIME, IN THE SAME INDIVIDUAL.

4462
02:57:23,360 --> 02:57:27,160
SO WHILE IT'S HELPFUL TO HAVE A

4463
02:57:27,160 --> 02:57:29,040
DEFINITION OF THE PATHOLOGY OF

4464
02:57:29,040 --> 02:57:34,840
THE  DISEASE HEALTH CONTINUUM

4465
02:57:34,840 --> 02:57:37,160
WE'RE GOING TO GET FURTHER WITH

4466
02:57:37,160 --> 02:57:37,800
MULTIPLE TREATMENTS THAT

4467
02:57:37,800 --> 02:57:39,040
SYSTEMATICALLY GO AT MULTIPLE

4468
02:57:39,040 --> 02:57:42,920
LEVEL TEST SAME TIME RATHER THAN

4469
02:57:42,920 --> 02:57:45,160
JUST GOING FOR ONE.

4470
02:57:45,160 --> 02:57:47,160
>> COULDN'T AGREE MORE, YEP,

4471
02:57:47,160 --> 02:57:47,360
UH-HUH.

4472
02:57:47,360 --> 02:57:50,880
THAT'S WHAT WE TALKED ABOUT AT

4473
02:57:50,880 --> 02:57:53,000
OUR WORKSHOP.

4474
02:57:53,000 --> 02:57:55,600
>> DR. JEAN LOUIS?

4475
02:57:55,600 --> 02:57:56,920
>>  THANK YOU.

4476
02:57:56,920 --> 02:58:00,200
I SHARE THE SKEPTICISM ABOUT

4477
02:58:00,200 --> 02:58:01,400
MEDICAL SCHOOLS BEING INTRODUCED

4478
02:58:01,400 --> 02:58:04,120
TO THE IDEA PALPATION IS

4479
02:58:04,120 --> 02:58:04,360
NECESSARY.

4480
02:58:04,360 --> 02:58:07,560
I HAVE GONE TO SOME DISASTER

4481
02:58:07,560 --> 02:58:09,360
PREPAREDNESS SESSIONS, WE TALK

4482
02:58:09,360 --> 02:58:09,920
ABOUT THAT.

4483
02:58:09,920 --> 02:58:12,080
SOMETIMES THAT'S ALL YOU HAVE.

4484
02:58:12,080 --> 02:58:14,280
IF IT'S SUCH AN IMPORTANT TOOL

4485
02:58:14,280 --> 02:58:16,040
AND IT'S NOT BEING TAUGHT IN

4486
02:58:16,040 --> 02:58:19,560
MEDICAL SCHOOL, MAYBE WE CAN

4487
02:58:19,560 --> 02:58:20,960
HAVE TRAINING PROGRAMS, SUMMER

4488
02:58:20,960 --> 02:58:22,520
INSTITUTE OF THE TIME PEOPLE CAN

4489
02:58:22,520 --> 02:58:24,120
COME FOR A COUPLE WEEKS TO

4490
02:58:24,120 --> 02:58:28,440
LEARN, I'M SURE A LOT OF 

4491
02:58:28,440 --> 02:58:29,960
STUDENTS MIGHT BE INTERESTED.

4492
02:58:29,960 --> 02:58:31,280
>> WE'VE ALL BEEN DEPRIVED OF

4493
02:58:31,280 --> 02:58:34,160
PHYSICAL CONTACT FOR THE LAST

4494
02:58:34,160 --> 02:58:35,960
TWO YEARS, YOU KNOW.

4495
02:58:35,960 --> 02:58:37,600
MAYBE WHEN PEOPLE CAN START TO

4496
02:58:37,600 --> 02:58:40,680
BE IN EACH OTHER'S PRESENCE

4497
02:58:40,680 --> 02:58:43,520
AGAIN PERHAPS TOUCHING ANOTHER

4498
02:58:43,520 --> 02:58:47,760
HUMAN BEING MIGHT INCREASE ITS

4499
02:58:47,760 --> 02:58:48,120
RELEVANCE.

4500
02:58:48,120 --> 02:58:50,560
>> DR. LANGEVIN, THE COURSE I

4501
02:58:50,560 --> 02:58:52,800
SPOKE OF THAT IS THE

4502
02:58:52,800 --> 02:58:55,560
INTRODUCTION TO PALPATION AND

4503
02:58:55,560 --> 02:58:56,680
MANUAL MEDICINE, WOULD IT BE

4504
02:58:56,680 --> 02:58:58,960
OKAY IF I PUT A LINK TO THAT IN

4505
02:58:58,960 --> 02:58:59,240
THE CHAT?

4506
02:58:59,240 --> 02:59:00,840
>>  SURE.

4507
02:59:00,840 --> 02:59:06,600
THANK YOU. 

4508
02:59:06,600 --> 02:59:06,880
WONDERFUL.

4509
02:59:06,880 --> 02:59:08,360
>> ANY OTHER QUESTIONS OR

4510
02:59:08,360 --> 02:59:10,520
COMMENTS BY COUNCIL MEMBERS OR

4511
02:59:10,520 --> 02:59:15,000
BY DR. CRISWELL AND LANGEVIN?

4512
02:59:15,000 --> 02:59:16,840
>>  WE'LL GIVE YOU THE LAST

4513
02:59:16,840 --> 02:59:17,280
WORD, LINDSEY.

4514
02:59:17,280 --> 02:59:18,720
>> THANK YOU FOR A REALLY

4515
02:59:18,720 --> 02:59:19,480
INTERESTING CONVERSATION.

4516
02:59:19,480 --> 02:59:21,880
I LEARNED A LOT AND I'M LOOKING

4517
02:59:21,880 --> 02:59:24,720
FORWARD TO SEEING HOW THESE

4518
02:59:24,720 --> 02:59:25,160
PROJECTS UNFOLD.

4519
02:59:25,160 --> 02:59:28,560
I THINK THEY ARE COVERING REALLY

4520
02:59:28,560 --> 02:59:29,600
IMPORTANT GROUND NOT ADDRESSED

4521
02:59:29,600 --> 02:59:30,200
IN OTHER WAYS.

4522
02:59:30,200 --> 02:59:32,360
THANK YOU FOR THE OPPORTUNITY.

4523
02:59:32,360 --> 02:59:34,440
LOOKING FORWARD TO CONTINUING

4524
02:59:34,440 --> 02:59:34,960
THE CONVERSATION.

4525
02:59:34,960 --> 02:59:35,960
>> WELL, THANK YOU FOR TAKING

4526
02:59:35,960 --> 02:59:38,160
TIME OUT OF YOUR BUSY DAY.

4527
02:59:38,160 --> 02:59:39,560
I KNOW HOW BUSY YOU ARE.

4528
02:59:39,560 --> 02:59:42,680
THANK FOUR  SPEND -- THANK YOU

4529
02:59:42,680 --> 02:59:44,400
FOR SPENDING THE TIME WITH US.

4530
02:59:44,400 --> 02:59:45,840
>> MY PLEASURE.

4531
02:59:45,840 --> 02:59:52,200
ENJOY THE REST OF YOUR

4532
02:59:52,200 --> 02:59:53,080
AFTERNOON.

4533
02:59:53,080 --> 02:59:55,160
>> WE'RE GOING TO NOW -- DR.

4534
02:59:55,160 --> 02:59:57,200
EMMELINE EDWARDS WILL GIVE THE

4535
02:59:57,200 --> 03:00:00,920
TALK WE WERE SCHEDULED ON THE

4536
03:00:00,920 --> 03:00:02,240
AGENDA BEFORE LUNCH, BECAUSE WE

4537
03:00:02,240 --> 03:00:05,320
GOT ENGROSSED IN ALL THESE OTHER

4538
03:00:05,320 --> 03:00:06,960
THINGS WE'RE SHIFTING.

4539
03:00:06,960 --> 03:00:09,520
WE HAVE TIME FOR EMMELINE TO

4540
03:00:09,520 --> 03:00:12,400
GIVE HER PRESENTATION ON THE

4541
03:00:12,400 --> 03:00:13,280
FUNDING OPPORTUNITY

4542
03:00:13,280 --> 03:00:14,520
ANNOUNCEMENTS THAT NCCIH IS

4543
03:00:14,520 --> 03:00:20,960
INVOLVED WITH RELATED TO PAIN 

4544
03:00:20,960 --> 03:00:21,320
RESEARCH.

4545
03:00:21,320 --> 03:00:26,680
DR. EDWARDS?

4546
03:00:26,680 --> 03:00:27,560
>>  JUST A MINUTE.

4547
03:00:27,560 --> 03:00:36,680
I'M TRYING TO PUT IT INTO VIEW.

4548
03:00:36,680 --> 03:00:49,480
OOPS. 

4549
03:00:49,480 --> 03:00:50,960
I'M TRYING TO PUT IT INTO VIEW

4550
03:00:50,960 --> 03:00:53,200
MODE.

4551
03:00:53,200 --> 03:01:00,840
 

4552
03:01:00,840 --> 03:01:02,280
I DON'T SEEM TO BE ABLE.

4553
03:01:02,280 --> 03:01:05,240
>> CAN DO YOU THE SLIDE SHOW

4554
03:01:05,240 --> 03:01:07,520
WHERE YOU'RE AT, SLIDE IT TO THE

4555
03:01:07,520 --> 03:01:09,280
RIGHT WHERE THE SLIDE SHOW ICON

4556
03:01:09,280 --> 03:01:09,440
IS?

4557
03:01:09,440 --> 03:01:16,800
>>  I GOT IT, YEAH.

4558
03:01:16,800 --> 03:01:17,960
>> TRY THAT.

4559
03:01:17,960 --> 03:01:19,160
>> YEAH, THANKS.

4560
03:01:19,160 --> 03:01:20,760
OKAY, SO, THANK YOU.

4561
03:01:20,760 --> 03:01:23,600
I'M GOING TO TRY TO DO THIS VERY

4562
03:01:23,600 --> 03:01:26,640
QUICKLY TO JUST GIVE YOU A VERY

4563
03:01:26,640 --> 03:01:28,960
QUICK OVERVIEW OF THE PLANS THAT

4564
03:01:28,960 --> 03:01:34,760
WE HAVE IN PLACE TO EXPAND OUR

4565
03:01:34,760 --> 03:01:37,280
PAIN PROGRAM TO ADDRESS GAPS IN

4566
03:01:37,280 --> 03:01:38,840
EXISTING PORTFOLIO AND LEVERAGE

4567
03:01:38,840 --> 03:01:39,800
THE OPPORTUNITIES THAT EXIST

4568
03:01:39,800 --> 03:01:43,960
ACROSS THE NIH AND OTHER FEDERAL

4569
03:01:43,960 --> 03:01:44,200
AGENCIES.

4570
03:01:44,200 --> 03:01:46,360
I SUSPECT MOST OF YOU HEARD THE

4571
03:01:46,360 --> 03:01:51,400
WORD "PAIN" FOR MOST OF THE DAY

4572
03:01:51,400 --> 03:01:53,400
BUT I WANT TO PUT WHAT I'M GOING

4573
03:01:53,400 --> 03:01:54,800
TO TALK ABOUT IN CONTEXT.

4574
03:01:54,800 --> 03:01:57,200
THIS IS DATA ACTUALLY FROM

4575
03:01:57,200 --> 03:02:03,360
PUBLICATION FROM TWO OF OUR

4576
03:02:03,360 --> 03:02:05,400
NCCIH STAFF, REALLY REMINDING US

4577
03:02:05,400 --> 03:02:08,720
MORE THAN 30% OF AMERICANS ARE

4578
03:02:08,720 --> 03:02:10,400
LIVING WITH SOME FORM OF CHRONIC

4579
03:02:10,400 --> 03:02:12,160
OR SEVERE PAIN AND MORE PEOPLE

4580
03:02:12,160 --> 03:02:14,360
LIVE WITH CHRONIC PAIN THAN

4581
03:02:14,360 --> 03:02:19,160
CANCER, HEART DISEASE, AND

4582
03:02:19,160 --> 03:02:20,040
DIABETES COMBINED.

4583
03:02:20,040 --> 03:02:21,760
ALSO WE'RE DEALING WITH

4584
03:02:21,760 --> 03:02:22,880
PREVALENCE OF DIFFERENT PROFILES

4585
03:02:22,880 --> 03:02:24,960
OF HIGH IMPACT CHRONIC PAIN IN

4586
03:02:24,960 --> 03:02:28,560
THE U.S., WITH LARGE PERCENTAGE

4587
03:02:28,560 --> 03:02:31,160
OF INDIVIDUALS REALLY HAVING

4588
03:02:31,160 --> 03:02:35,640
SEVERE LIMITATION OF THE

4589
03:02:35,640 --> 03:02:35,920
FUNCTION.

4590
03:02:35,920 --> 03:02:39,440
MOST OF YOU COULD HAVE MISSED

4591
03:02:39,440 --> 03:02:39,760
THIS RELEASE.

4592
03:02:39,760 --> 03:02:41,760
THIS OCCURRED DURING THE

4593
03:02:41,760 --> 03:02:42,200
HOLIDAY.

4594
03:02:42,200 --> 03:02:46,080
IT WAS RELEASED ON DECEMBER 27,

4595
03:02:46,080 --> 03:02:47,440
2021.

4596
03:02:47,440 --> 03:02:49,880
AND THIS WAS ACTUALLY NOTICE OF

4597
03:02:49,880 --> 03:02:58,600
INFORMATION THAT WAS PUT BY  THE

4598
03:02:58,600 --> 03:03:01,560
I.C. DIRECTORS OF SEVEN

4599
03:03:01,560 --> 03:03:03,160
INSTITUTION ALERTING OF INTEREST

4600
03:03:03,160 --> 03:03:05,280
IN PAIN RESEARCH.

4601
03:03:05,280 --> 03:03:07,800
NOT ONLY RESEARCH BUT ALSO

4602
03:03:07,800 --> 03:03:10,560
TRAINING PROGRAMS TO BUILD A

4603
03:03:10,560 --> 03:03:12,000
MORE EFFECTIVE AND INTEGRATED

4604
03:03:12,000 --> 03:03:14,760
WORKFORCE IN PAIN RESEARCH.

4605
03:03:14,760 --> 03:03:16,960
THAT INTEREST SPANNED BASIC

4606
03:03:16,960 --> 03:03:20,960
RESEARCH ON PAIN CIRCUITS, PAIN

4607
03:03:20,960 --> 03:03:22,200
MECHANISM, UNDERSTANDING THE

4608
03:03:22,200 --> 03:03:25,040
BIOLOGICAL BASIS OF MULTIPLE

4609
03:03:25,040 --> 03:03:26,360
PAIN DISORDERS, AND ALSO

4610
03:03:26,360 --> 03:03:28,320
RESEARCH THAT WOULD IDENTIFY

4611
03:03:28,320 --> 03:03:31,920
RISK FACTORS FOR CHRONIC PAIN,

4612
03:03:31,920 --> 03:03:34,440
AS WELL AS AREAS OF INTEREST

4613
03:03:34,440 --> 03:03:37,400
INCLUDING HEALTH DISPARITY,

4614
03:03:37,400 --> 03:03:38,400
HEALTH EQUITY.

4615
03:03:38,400 --> 03:03:42,400
BUT I ALSO WANT TO PUT IT INTO

4616
03:03:42,400 --> 03:03:43,960
THE CONTEXT OF NCCIH, BECAUSE

4617
03:03:43,960 --> 03:03:47,160
ONE OF THE TOP TEN SCIENTIFIC

4618
03:03:47,160 --> 03:03:49,560
PRIORITIES THAT WE HIGHLIGHTED

4619
03:03:49,560 --> 03:03:51,960
IN OUR STRATEGIC PLAN WAS

4620
03:03:51,960 --> 03:03:53,240
COMPLEMENTARY AND INTEGRATIVE

4621
03:03:53,240 --> 03:03:53,880
MANAGEMENT OF PAIN.

4622
03:03:53,880 --> 03:04:00,680
AND SO OUR STRATEGIC PLAN WAS

4623
03:04:00,680 --> 03:04:01,880
RELEASED IN EARLY SUMMER 2021,

4624
03:04:01,880 --> 03:04:04,160
AND THEREFORE I CAN SAY THAT WE

4625
03:04:04,160 --> 03:04:05,720
WERE VERY MUCH AHEAD OF THE

4626
03:04:05,720 --> 03:04:08,120
CURVE BECAUSE WE HAD HIGHLIGHTED

4627
03:04:08,120 --> 03:04:10,360
MANY OF THOSE AREAS OF INTEREST

4628
03:04:10,360 --> 03:04:12,120
AS WELL.

4629
03:04:12,120 --> 03:04:16,760
PAIN MECHANISM AND PHENOTYPE, 

4630
03:04:16,760 --> 03:04:17,920
OVERLAPPING CONDITION, HEALTH

4631
03:04:17,920 --> 03:04:21,520
DISPARITIES IN PAIN, EFFICACY

4632
03:04:21,520 --> 03:04:23,160
AND EFFECTIVENESS OF

4633
03:04:23,160 --> 03:04:25,560
COMPLEMENTARY APPROACHES, AND

4634
03:04:25,560 --> 03:04:26,360
UNDERSTANDING MULTI-SYSTEM

4635
03:04:26,360 --> 03:04:29,520
MECHANISM UNDERLYING EFFECT OF

4636
03:04:29,520 --> 03:04:31,160
OUR STRATEGIES.

4637
03:04:31,160 --> 03:04:34,640
IMPORTANTLY WE HAD RECOGNIZED

4638
03:04:34,640 --> 03:04:37,280
POTENTIAL OF LEVERAGING "HEAL"

4639
03:04:37,280 --> 03:04:39,320
AND TRANS-NIH AND TRANSAGENCY

4640
03:04:39,320 --> 03:04:43,400
PROGRAMS TO IDENTIFY THERAPEUTIC

4641
03:04:43,400 --> 03:04:44,560
BIOMARKERS FOR COMPLEMENTARY AND

4642
03:04:44,560 --> 03:04:46,480
INTEGRATIVE APPROACHES ON PAIN.

4643
03:04:46,480 --> 03:04:48,760
WE CONTINUE TO HAVE AN INTEREST

4644
03:04:48,760 --> 03:04:50,840
IN IMPROVED METHODS TO

4645
03:04:50,840 --> 03:04:52,520
INCORPORATE OUR APPROACHES TO

4646
03:04:52,520 --> 03:04:57,120
STANDARD CARE TO TREAT PAIN AND 

4647
03:04:57,120 --> 03:04:59,600
DECREASE USE OF OPIOIDS.

4648
03:04:59,600 --> 03:05:04,960
SO I'M GOING TO HIGHLIGHT TWO

4649
03:05:04,960 --> 03:05:06,280
FUNDING OPPORTUNITY

4650
03:05:06,280 --> 03:05:08,000
ANNOUNCEMENTS CURRENTLY OPEN

4651
03:05:08,000 --> 03:05:10,160
THAT NCCIH HAS WORKED HARD TO

4652
03:05:10,160 --> 03:05:13,280
PUT OUT SOMETIME IN NOVEMBER.

4653
03:05:13,280 --> 03:05:15,280
FIRST OPPORTUNITY IS NOTICE OF

4654
03:05:15,280 --> 03:05:19,120
SPECIAL INTEREST FOR

4655
03:05:19,120 --> 03:05:21,080
ADMINISTRATIVE SUPPLEMENTS TO

4656
03:05:21,080 --> 03:05:25,000
NCCIH-FUNDED GRANTS.

4657
03:05:25,000 --> 03:05:25,960
THOSE ARE ONE-YEAR SUPPLEMENTS,

4658
03:05:25,960 --> 03:05:27,640
GRANTS HAVE TO HAVE AT LEAST 18

4659
03:05:27,640 --> 03:05:31,160
MONTHS LEFT IN THEIR LIFE CYCLE

4660
03:05:31,160 --> 03:05:36,040
TO BE ABLE TO ELIGIBLE FOR

4661
03:05:36,040 --> 03:05:36,560
SUPPLEMENT.

4662
03:05:36,560 --> 03:05:38,560
JUST ONE CAVEAT IS THAT IT HAS

4663
03:05:38,560 --> 03:05:42,560
TO BE WITHIN THE SCOPE OF THE

4664
03:05:42,560 --> 03:05:45,040
ORIGINAL PROJECT BUT THOSE --

4665
03:05:45,040 --> 03:05:46,160
THIS OPPORTUNITY ALLOWS

4666
03:05:46,160 --> 03:05:48,000
INVESTIGATORS TO SUBMIT THOSE

4667
03:05:48,000 --> 03:05:49,640
SUPPLEMENTS FOR ONE YEAR AND

4668
03:05:49,640 --> 03:05:52,040
THEY ARE REVIEWED BY OUR PROGRAM

4669
03:05:52,040 --> 03:05:53,320
STAFF.

4670
03:05:53,320 --> 03:05:56,000
SO THIS OPPORTUNITY IS STILL

4671
03:05:56,000 --> 03:05:57,400
OPEN UNTIL MAY OF 2022.

4672
03:05:57,400 --> 03:06:00,320
AND I WILL TELL YOU IN A MINUTE

4673
03:06:00,320 --> 03:06:01,760
AREAS OF FOCUS FOR THESE

4674
03:06:01,760 --> 03:06:02,560
OPPORTUNITIES.

4675
03:06:02,560 --> 03:06:05,800
WE ALSO HAVE A SECOND NOTICE OF

4676
03:06:05,800 --> 03:06:09,080
SPECIAL INTEREST, MORE FOCUSED

4677
03:06:09,080 --> 03:06:13,760
ON LONGER TERM RESEARCH GRANTS,

4678
03:06:13,760 --> 03:06:19,760
STANDARD R01, EXPLORATORY AND

4679
03:06:19,760 --> 03:06:22,160
DEVELOPMENTAL GRANT, ALSO OUR

4680
03:06:22,160 --> 03:06:24,040
PROFILES, THIS OPPORTUNITY

4681
03:06:24,040 --> 03:06:25,320
EXPIRES IN DECEMBER 2022.

4682
03:06:25,320 --> 03:06:27,960
LATER ON THIS AFTERNOON YOU'LL

4683
03:06:27,960 --> 03:06:30,720
HEAR CONCEPT CLEARANCE THAT WILL

4684
03:06:30,720 --> 03:06:32,440
FURTHER EXTEND THE TIMELINE OF

4685
03:06:32,440 --> 03:06:34,000
SUCH OPPORTUNITIES.

4686
03:06:34,000 --> 03:06:38,160
THE AREAS OF FOCUS FOR THESE TWO

4687
03:06:38,160 --> 03:06:42,760
IS HIGHLIGHTED IN THIS SLIDE,

4688
03:06:42,760 --> 03:06:46,680
THE EARLIER HELENE MENTIONED

4689
03:06:46,680 --> 03:06:47,960
SUCCESSFUL WORKSHOP IN JULY 2021

4690
03:06:47,960 --> 03:06:51,360
TO SICKLE CELL PAIN SO ONE OF

4691
03:06:51,360 --> 03:06:54,440
THE AREAS AND ONE RESEARCH GAP

4692
03:06:54,440 --> 03:06:59,360
IN OUR PORTFOLIO TO BETTER

4693
03:06:59,360 --> 03:07:01,440
UNDERSTAND RESEARCH ON PAIN

4694
03:07:01,440 --> 03:07:03,200
RELATED TO SICKLE CELL DISEASE.

4695
03:07:03,200 --> 03:07:06,240
AT THE WORKSHOP IT BECAME CLEAR

4696
03:07:06,240 --> 03:07:08,120
THAT WHILE THERE ARE, YOU KNOW,

4697
03:07:08,120 --> 03:07:10,000
IMPROVEMENTS IN TERMS OF

4698
03:07:10,000 --> 03:07:13,520
TREATMENT FOR SICKLE CELL, AT

4699
03:07:13,520 --> 03:07:17,440
LEAST THE VASCULAR ASPECT, WITH

4700
03:07:17,440 --> 03:07:21,760
STEM CELLS TRANSPLANTS AND ALSO

4701
03:07:21,760 --> 03:07:24,680
ARE GENE THERAPY, THE PAIN

4702
03:07:24,680 --> 03:07:26,120
ASSOCIATED WITH SICKLE CELL

4703
03:07:26,120 --> 03:07:27,760
CONTINUES IN MANY PATIENTS.

4704
03:07:27,760 --> 03:07:29,160
WE REALLY DON'T UNDERSTAND THE

4705
03:07:29,160 --> 03:07:30,320
MECHANISM OF HOW THAT HAPPENS.

4706
03:07:30,320 --> 03:07:33,680
SO THIS IS A GAP AREA THAT WE'RE

4707
03:07:33,680 --> 03:07:36,080
VERY MUCH INTERESTED IN.

4708
03:07:36,080 --> 03:07:38,720
WE ARE ALSO ENCOURAGING LOTS OF

4709
03:07:38,720 --> 03:07:44,240
BASIC AND MECHANISTIC

4710
03:07:44,240 --> 03:07:45,560
UNDERSTANDING OF MYOFASCIAL

4711
03:07:45,560 --> 03:07:45,760
PAIN.

4712
03:07:45,760 --> 03:07:50,400
YOU HEARD ABOUT DEVELOPMENT OF

4713
03:07:50,400 --> 03:07:52,000
THE WORKSHOP FOR FORCE-BASED

4714
03:07:52,000 --> 03:07:55,280
MANIPULATION, WE WANT TO

4715
03:07:55,280 --> 03:07:57,880
ENCOURAGE FUNDAMENTAL SCIENCE OF

4716
03:07:57,880 --> 03:07:58,560
FORCE-BASED INTERVENTION, TO

4717
03:07:58,560 --> 03:08:00,720
PREVENT OR MANAGE PAIN.

4718
03:08:00,720 --> 03:08:02,880
WE WANT TO FURTHER IDENTIFY

4719
03:08:02,880 --> 03:08:05,400
NOVEL THERAPEUTIC TARGETS OF

4720
03:08:05,400 --> 03:08:08,560
PAIN FOR NON-ADDICTIVE NATURAL

4721
03:08:08,560 --> 03:08:10,280
PRODUCTS.

4722
03:08:10,280 --> 03:08:12,800
AND WE WANT TO ENCOURAGE SCIENCE

4723
03:08:12,800 --> 03:08:15,080
TO ENHANCE PAIN MANAGEMENT.

4724
03:08:15,080 --> 03:08:17,160
YOU HEARD SOME OTHER ASPECT THIS

4725
03:08:17,160 --> 03:08:19,240
MORNING IN THAT DISCUSSION OF

4726
03:08:19,240 --> 03:08:21,120
THE HIGH PROGRAM PRIORITY,

4727
03:08:21,120 --> 03:08:23,520
CONCEPT IS REALLY TO EXPAND

4728
03:08:23,520 --> 03:08:26,000
MUSIC THERAPY TO ENHANCE PAIN

4729
03:08:26,000 --> 03:08:26,440
MANAGEMENT.

4730
03:08:26,440 --> 03:08:29,960
OF COURSE WE'RE INTERESTED IN

4731
03:08:29,960 --> 03:08:31,560
MULTI-COMPONENT PAIN MANAGEMENT

4732
03:08:31,560 --> 03:08:34,640
INTERVENTION DEVELOPMENT, AND

4733
03:08:34,640 --> 03:08:36,160
TRIALS OF COMPLEMENTARY

4734
03:08:36,160 --> 03:08:40,120
APPROACHES, DELIVERED REMOTELY

4735
03:08:40,120 --> 03:08:42,760
OR VIA MHEALTH, THE CURRENT HIGH

4736
03:08:42,760 --> 03:08:44,720
PRIORITY TOPICS THAT ARE

4737
03:08:44,720 --> 03:08:46,320
DELINEATED IN THE OPPORTUNITIES

4738
03:08:46,320 --> 03:08:48,120
THAT WE HAVE CURRENTLY OUT

4739
03:08:48,120 --> 03:08:52,760
THERE. 

4740
03:08:52,760 --> 03:08:55,200
YOU'VE ALREADY HEARD THIS

4741
03:08:55,200 --> 03:08:56,760
FUNDING OPPORTUNITY ANNOUNCEMENT

4742
03:08:56,760 --> 03:09:02,400
WHICH EXPANDS OUR CURRENT

4743
03:09:02,400 --> 03:09:04,960
NIH-DoD-VA PAIN MANAGEMENT.

4744
03:09:04,960 --> 03:09:08,160
THERE'S STILL TIME, ON MARCH 26,

4745
03:09:08,160 --> 03:09:10,120
2022, IS THE DEADLINE.

4746
03:09:10,120 --> 03:09:16,840
OF COURSE, YOU'VE ALSO HEARD OF 

4747
03:09:16,840 --> 03:09:20,200
THE RFA FOR MYOFASCIAL PAIN,

4748
03:09:20,200 --> 03:09:21,040
DEVELOPING QUANTITATIVE IMAGING

4749
03:09:21,040 --> 03:09:21,960
AND OTHER BIOMARKERS.

4750
03:09:21,960 --> 03:09:25,160
TIME IS LIMITED HERE BUT YOU

4751
03:09:25,160 --> 03:09:28,160
STILL HAVE TIME, FEBRUARY 11.

4752
03:09:28,160 --> 03:09:29,600
SICKLE CELL PAIN WE'VE

4753
03:09:29,600 --> 03:09:31,320
ALREADY -- WE HAD TWO

4754
03:09:31,320 --> 03:09:32,240
OPPORTUNITIES THAT ARE NOW

4755
03:09:32,240 --> 03:09:35,240
CLOSED BUT THEY WERE PRIMARILY

4756
03:09:35,240 --> 03:09:37,000
FOCUSED ON PRAGMATIC AND

4757
03:09:37,000 --> 03:09:38,920
INTERVENTION STUDIES, AND ALSO

4758
03:09:38,920 --> 03:09:40,400
ON EFFECTIVENESS RESEARCH.

4759
03:09:40,400 --> 03:09:46,440
SO NOW  THAT IS WHY WE WANT TO

4760
03:09:46,440 --> 03:09:49,080
MOVE INTO BASIC AND MECHANISTIC

4761
03:09:49,080 --> 03:09:50,520
ASPECT AND CURRENT OPPORTUNITY

4762
03:09:50,520 --> 03:09:51,840
ON ADVANCING HEALTH EQUITY IN

4763
03:09:51,840 --> 03:09:57,960
PAIN MANAGEMENT THAT IS STILL

4764
03:09:57,960 --> 03:10:00,880
OPEN.

4765
03:10:00,880 --> 03:10:05,720
THERE ARE MULTIPLE EXAMPLES OF

4766
03:10:05,720 --> 03:10:08,640
NIH "HEAL" RFAs OUT THERE.

4767
03:10:08,640 --> 03:10:11,760
GO ON THE NCCIH WEB PAGE OR

4768
03:10:11,760 --> 03:10:13,600
DIRECTLY ON THE HEAL WEB PAGE,

4769
03:10:13,600 --> 03:10:14,720
THERE ARE CONSTANTLY NEW

4770
03:10:14,720 --> 03:10:14,960
ADDITIONS.

4771
03:10:14,960 --> 03:10:19,320
I'LL MENTION THERE ARE CURRENTLY

4772
03:10:19,320 --> 03:10:21,800
OPPORTUNITIES THAT ARE AVAILABLE

4773
03:10:21,800 --> 03:10:32,200
UNTIL APRIL AND JUNE, FOCUSED ON

4774
03:10:32,200 --> 03:10:32,760
ANALGESIC DEVELOPMENT,

4775
03:10:32,760 --> 03:10:34,160
TRANSLATIONAL RESEARCH,

4776
03:10:34,160 --> 03:10:35,720
DEVELOPMENT OF THERAPIES AND

4777
03:10:35,720 --> 03:10:38,200
TECHNOLOGIES THAT ARE FOCUSED ON

4778
03:10:38,200 --> 03:10:39,200
ENHANCING PAIN MANAGEMENT.

4779
03:10:39,200 --> 03:10:41,600
IF YOU'RE INTERESTED IN THOSE

4780
03:10:41,600 --> 03:10:43,240
AREAS, PLEASE VISIT THE WEBSITE

4781
03:10:43,240 --> 03:10:46,960
AND ACTUALLY GET THE SPECIFICS

4782
03:10:46,960 --> 03:10:48,560
ON THOSE RFAs.

4783
03:10:48,560 --> 03:10:52,960
YOU JUST HEARD THE WONDERFUL

4784
03:10:52,960 --> 03:10:55,160
PRESENTATION ABOUT THE RE-JOIN

4785
03:10:55,160 --> 03:10:55,920
INITIATIVE.

4786
03:10:55,920 --> 03:10:59,320
WE'RE REALLY EXCITED ABOUT THIS

4787
03:10:59,320 --> 03:11:02,080
AND HEARING HELENE'S VISION FOR

4788
03:11:02,080 --> 03:11:06,880
MOVING  MOVING INTO WHOLE JOINT

4789
03:11:06,880 --> 03:11:09,240
HEALTH IS EXCITING AND WE'RE

4790
03:11:09,240 --> 03:11:11,160
LOOKING FORWARD TO FURTHER

4791
03:11:11,160 --> 03:11:12,680
DEVELOPING THOSE PROGRAMS.

4792
03:11:12,680 --> 03:11:14,840
THERE ARE A COUPLE HEAL RESEARCH

4793
03:11:14,840 --> 03:11:16,560
OPPORTUNITIES I'D LIKE TO

4794
03:11:16,560 --> 03:11:19,120
HIGHLIGHT, MORE FOCUSED ON

4795
03:11:19,120 --> 03:11:21,200
SERVICE DELIVERY.

4796
03:11:21,200 --> 03:11:24,960
THOSE ARE OUR NCCIH STAFF HAS A

4797
03:11:24,960 --> 03:11:27,880
VERY STRONG INFLUENCE INTO THE

4798
03:11:27,880 --> 03:11:29,160
DEVELOPMENT OF THOSE PROGRAMS,

4799
03:11:29,160 --> 03:11:35,320
THE FIRST ONE IS ACTUALLY ISSUED

4800
03:11:35,320 --> 03:11:39,480
THROUGH NIDA AS THE LEAD, IT'S

4801
03:11:39,480 --> 03:11:41,760
THE HEAL DATA2ACTION PROGRAM, A

4802
03:11:41,760 --> 03:11:44,840
SET OF FOUR INTERRELATED RFAs

4803
03:11:44,840 --> 03:11:47,360
TO PROMOTE SYNTHESIS IN REAL

4804
03:11:47,360 --> 03:11:50,320
WORLD APPLICATION OF EXISTING

4805
03:11:50,320 --> 03:11:52,280
DATA, ALSO GUIDING AND

4806
03:11:52,280 --> 03:11:53,360
MONITORING IMPROVEMENT IN

4807
03:11:53,360 --> 03:11:57,160
SERVICE DELIVERY TO PREVENT OR 

4808
03:11:57,160 --> 03:11:58,800
TREAT OPIOID USE DISORDERS IN

4809
03:11:58,800 --> 03:11:59,000
PAIN.

4810
03:11:59,000 --> 03:12:04,160
ONE OF THE RFAs IS FOCUSED ON

4811
03:12:04,160 --> 03:12:05,840
INNOVATION RESEARCH GRANTS,

4812
03:12:05,840 --> 03:12:06,600
SUPPORTED BY THREE RESOURCE

4813
03:12:06,600 --> 03:12:07,600
CENTERS.

4814
03:12:07,600 --> 03:12:12,280
ONE WOULD BE  FOCUSED ON

4815
03:12:12,280 --> 03:12:14,320
MODELING, THE OTHER ON ADOPTION

4816
03:12:14,320 --> 03:12:16,040
AND IMPLEMENTATION SCIENCE,

4817
03:12:16,040 --> 03:12:18,600
THIRD ON DATA INFRASTRUCTURE.

4818
03:12:18,600 --> 03:12:21,440
WENDY WEBER HAS BEEN

4819
03:12:21,440 --> 03:12:24,400
INSTRUMENTAL IN PARTICIPATING IN

4820
03:12:24,400 --> 03:12:26,800
DEVELOPMENT OF THOSE RESEARCH

4821
03:12:26,800 --> 03:12:31,800
FUNDING  OPPORTUNITIES, END DATE

4822
03:12:31,800 --> 03:12:33,560
IS MARCH 11 THIS YEAR.

4823
03:12:33,560 --> 03:12:36,000
WE HAVE STILL IN THE SAME VEIN

4824
03:12:36,000 --> 03:12:38,400
IN TERMS OF SERVICE DELIVERY,

4825
03:12:38,400 --> 03:12:41,280
PETE MURRAY HAS BEEN INVOLVED IN

4826
03:12:41,280 --> 03:12:44,760
MANY OF THE DEVELOPMENT OF THESE

4827
03:12:44,760 --> 03:12:48,280
RFAs, ONE IS FOCUSED ON POLY

4828
03:12:48,280 --> 03:12:50,000
SUBSTANCE USE, INCLUDING BOTH

4829
03:12:50,000 --> 03:12:51,760
IMPROVEMENT OF SERVICE DELIVERY

4830
03:12:51,760 --> 03:12:55,680
TO THE REGULAR R01 MECHANISM,

4831
03:12:55,680 --> 03:12:57,920
AND ALSO FEASIBILITY TRIALS TO

4832
03:12:57,920 --> 03:12:58,760
IMPROVE PREVENTION AND

4833
03:12:58,760 --> 03:12:59,520
TREATMENT.

4834
03:12:59,520 --> 03:13:03,640
WE HAVE A COUPLE RFAs FOCUSED

4835
03:13:03,640 --> 03:13:08,600
ON SERVICES FOR INDIVIDUALS

4836
03:13:08,600 --> 03:13:11,960
RECEIVING MEDICATION ASSISTED

4837
03:13:11,960 --> 03:13:12,760
SERVICES.

4838
03:13:12,760 --> 03:13:14,120
AGAIN, EXPIRATION DATE MARCH

4839
03:13:14,120 --> 03:13:14,640
2022.

4840
03:13:14,640 --> 03:13:17,160
YOU CAN SEE THOSE RFAs HAVE

4841
03:13:17,160 --> 03:13:21,120
BEEN PUT IN PLACE IN ORDER TO

4842
03:13:21,120 --> 03:13:23,520
ENSURE THAT WE'RE READY IN CASE,

4843
03:13:23,520 --> 03:13:26,360
YOU KNOW, WE GET THAT LARGE

4844
03:13:26,360 --> 03:13:28,560
INFLUX OF MONEY.

4845
03:13:28,560 --> 03:13:29,200
BUT THERE'S PLENTY OF

4846
03:13:29,200 --> 03:13:34,160
OPPORTUNITIES FOR US TO BE ABLE 

4847
03:13:34,160 --> 03:13:37,280
TO FULFILL THAT MANDATE.

4848
03:13:37,280 --> 03:13:41,560
FINALLY, WE ALSO HAVE A SET OF

4849
03:13:41,560 --> 03:13:43,440
RFAs FOCUSED ON HARM REDUCTION

4850
03:13:43,440 --> 03:13:45,840
POLICIES, DEVELOPMENT OF DATA

4851
03:13:45,840 --> 03:13:49,000
AND METHODS TO ADDRESS THE

4852
03:13:49,000 --> 03:13:50,480
URGENT NEED FOR OPIOID EPIDEMIC.

4853
03:13:50,480 --> 03:13:54,480
I WANT TO TAKE THE OPPORTUNITY

4854
03:13:54,480 --> 03:13:58,760
TO REALLY APPLAUD OUR STAFF THAT

4855
03:13:58,760 --> 03:14:01,160
HAVE WORKED REALLY HARD UNDER

4856
03:14:01,160 --> 03:14:04,840
VERY, VERY SHORT NOTICES TO COME

4857
03:14:04,840 --> 03:14:09,320
UP WITH GREAT IDEAS AND PUT THEM

4858
03:14:09,320 --> 03:14:13,000
TOGETHER INTO VERY, VERY

4859
03:14:13,000 --> 03:14:16,120
COHERENT AND IMPACTFUL FUNDING

4860
03:14:16,120 --> 03:14:17,160
OPPORTUNITY ANNOUNCEMENTS.

4861
03:14:17,160 --> 03:14:20,560
AND SO THE MESSAGE IS THERE THAT

4862
03:14:20,560 --> 03:14:24,360
THERE'S A LOT OF INTEREST IN

4863
03:14:24,360 --> 03:14:25,480
PAIN RESEARCH, IT'S WELL

4864
03:14:25,480 --> 03:14:26,560
JUSTIFIED.

4865
03:14:26,560 --> 03:14:29,320
THIS IS AN ENORMOUS PROBLEM FOR

4866
03:14:29,320 --> 03:14:30,960
OUR POPULATION.

4867
03:14:30,960 --> 03:14:32,600
AND THE NIH REALLY HAS TAKEN A

4868
03:14:32,600 --> 03:14:36,480
LOT OF STEPS TO ACTUALLY REALLY

4869
03:14:36,480 --> 03:14:39,920
ADDRESS SOME OF THESE ISSUES AND

4870
03:14:39,920 --> 03:14:41,080
PROVIDE OPPORTUNITIES FOR

4871
03:14:41,080 --> 03:14:41,680
INVESTIGATORS IN MULTIPLE

4872
03:14:41,680 --> 03:14:45,200
DOMAINS AND I DO HOPE THAT YOU

4873
03:14:45,200 --> 03:14:47,160
TAKE ADVANTAGE OF ALL THESE

4874
03:14:47,160 --> 03:14:50,160
PROGRAMS AND PLEASE MAKE SURE

4875
03:14:50,160 --> 03:14:54,080
THAT YOU CONTACT US AND DISCUSS

4876
03:14:54,080 --> 03:14:57,160
YOUR IDEAS AND SUBMIT YOUR

4877
03:14:57,160 --> 03:14:57,480
APPLICATIONS.

4878
03:14:57,480 --> 03:15:00,560
SO WITH THAT, IF YOU HAVE ANY

4879
03:15:00,560 --> 03:15:03,400
QUESTIONS, I'LL BE HAPPY TO

4880
03:15:03,400 --> 03:15:07,760
ANSWER THEM. 

4881
03:15:07,760 --> 03:15:10,040
>> QUESTIONS FROM COUNCIL FOR

4882
03:15:10,040 --> 03:15:26,080
DR. EDWARDS? 

4883
03:15:26,080 --> 03:15:27,360
>> I THINK EVERYBODY IS

4884
03:15:27,360 --> 03:15:29,120
SATURATED WITH HEARING THE WORD

4885
03:15:29,120 --> 03:15:36,160
"PAIN" AND ALSO THE WORD

4886
03:15:36,160 --> 03:15:36,480
"OPPORTUNITY."

4887
03:15:36,480 --> 03:15:38,080
>> DR. EDWARDS, THANK YOU SO

4888
03:15:38,080 --> 03:15:39,640
MUCH FOR SHARING THAT WITH US.

4889
03:15:39,640 --> 03:15:43,000
I JUST WANTED TO ASK, I KNOW

4890
03:15:43,000 --> 03:15:44,880
THERE'S EXISTING INITIATIVES AND

4891
03:15:44,880 --> 03:15:47,320
THEN THERE'S THIS POSSIBILITY OF

4892
03:15:47,320 --> 03:15:48,360
ADDITIONAL BUDGET, AND OF COURSE

4893
03:15:48,360 --> 03:15:51,240
THE NEED TO MOVE QUICKLY IF THAT

4894
03:15:51,240 --> 03:15:52,560
BUDGET DOES BECOME AVAILABLE.

4895
03:15:52,560 --> 03:15:59,160
AND I KNOW THAT THAT PUTS

4896
03:15:59,160 --> 03:16:01,760
TREMENDOUS PRESSURE ON STAFF AND

4897
03:16:01,760 --> 03:16:03,160
PEOPLE WRITING PROPOSALS IF THE

4898
03:16:03,160 --> 03:16:04,640
BUDGET DOES BECOME AVAILABLE.

4899
03:16:04,640 --> 03:16:06,320
I WONDER WHETHER THE STRATEGY IS

4900
03:16:06,320 --> 03:16:11,160
TO TAKE ADVANTAGE OF THE

4901
03:16:11,160 --> 03:16:12,600
EXISTING INITIATIVES AND EXPAND

4902
03:16:12,600 --> 03:16:14,320
THE AMOUNT OF COVERAGE, IF THAT

4903
03:16:14,320 --> 03:16:16,640
BUDGET DOES BECOME AVAILABLE, OR

4904
03:16:16,640 --> 03:16:18,600
IF IT'S TO TRY TO CREATE NEW

4905
03:16:18,600 --> 03:16:19,600
INITIATIVES AND IF THERE'S

4906
03:16:19,600 --> 03:16:21,320
ALREADY SOME PLANNING FOR WHAT

4907
03:16:21,320 --> 03:16:24,080
THOSE MIGHT BE, IF INDEED THE

4908
03:16:24,080 --> 03:16:24,800
BUDGET DID COME AVAILABLE?

4909
03:16:24,800 --> 03:16:29,800
>>  I THINK THAT'S WHY WE

4910
03:16:29,800 --> 03:16:30,760
ACTUALLY ADOPTED THIS

4911
03:16:30,760 --> 03:16:31,400
MULTI-PRONGED APPROACH.

4912
03:16:31,400 --> 03:16:33,960
WE STARTED OUT WITH THE

4913
03:16:33,960 --> 03:16:36,120
SUPPLEMENT INITIATIVE.

4914
03:16:36,120 --> 03:16:37,640
THAT WOULD GIVE, YOU KNOW,

4915
03:16:37,640 --> 03:16:38,880
INVESTIGATORS AN OPPORTUNITY TO

4916
03:16:38,880 --> 03:16:40,920
KIND OF DIP THEIR TOES IN THE

4917
03:16:40,920 --> 03:16:41,800
WATER AND START GETTING

4918
03:16:41,800 --> 03:16:43,440
PRELIMINARY DATA AND THEN LATER

4919
03:16:43,440 --> 03:16:48,800
ON APPLY FOR THE EXISTING

4920
03:16:48,800 --> 03:16:49,240
NOTICE.

4921
03:16:49,240 --> 03:16:50,680
LATER ON THIS AFTERNOON WE'RE

4922
03:16:50,680 --> 03:16:53,880
GOING TO HAVE THE CONCEPT

4923
03:16:53,880 --> 03:16:56,160
CLEARANCE THAT'S GOING TO AGAIN

4924
03:16:56,160 --> 03:16:57,320
EXTEND THE TIMELINE BEYOND 2022.

4925
03:16:57,320 --> 03:16:59,200
I THINK THAT'S WHAT WE'RE

4926
03:16:59,200 --> 03:17:03,120
THINKING IS THAT WE DO REALIZE

4927
03:17:03,120 --> 03:17:06,600
THIS IS AN EXTREMELY AMBITIOUS

4928
03:17:06,600 --> 03:17:09,560
TIMELINE, BUT IN ORDER TO MEET

4929
03:17:09,560 --> 03:17:14,560
THE MANDATE AND ACTUALLY BE ABLE

4930
03:17:14,560 --> 03:17:17,520
TO ACCESS THE BUDGET, IF WE GET

4931
03:17:17,520 --> 03:17:19,880
IT, THAT WE HAVE VERY LITTLE

4932
03:17:19,880 --> 03:17:22,760
CHOICE TO DO THAT.

4933
03:17:22,760 --> 03:17:25,600
SO, YOU KNOW, IT'S REALLY A

4934
03:17:25,600 --> 03:17:27,560
STRESSOR OR NOT ONLY NIH STAFF

4935
03:17:27,560 --> 03:17:31,720
BUT ALSO ON INVESTIGATORS AS

4936
03:17:31,720 --> 03:17:32,040
WELL.

4937
03:17:32,040 --> 03:17:37,200
BUT IT IS WHAT IT IS.

4938
03:17:37,200 --> 03:17:40,160
>> SOUNDS LIKE THE BEST POSSIBLE

4939
03:17:40,160 --> 03:17:40,960
STRATEGY.

4940
03:17:40,960 --> 03:17:43,440
>> YES. 

4941
03:17:43,440 --> 03:17:44,840
>> IF I COULD ADD, AT THE

4942
03:17:44,840 --> 03:17:48,720
BEGINNING WE WANTED TO RULE OUT

4943
03:17:48,720 --> 03:17:50,560
STARTING ENTIRELY NEW

4944
03:17:50,560 --> 03:17:52,080
INITIATIVES, DE NOVO, YOU KNOW,

4945
03:17:52,080 --> 03:17:53,160
THE RE-JOIN INITIATIVE YOU JUST

4946
03:17:53,160 --> 03:17:56,560
HEARD IS ONE OF THE FEW THAT

4947
03:17:56,560 --> 03:17:58,880
ACTUALLY GOT PUSHED THROUGH, THE

4948
03:17:58,880 --> 03:18:01,960
HEAL INITIATIVE, FOR FY 22, BUT

4949
03:18:01,960 --> 03:18:03,800
THE TIMELINE FOR SUBMITTING

4950
03:18:03,800 --> 03:18:06,520
APPLICATIONS IS VERY SHORT,

4951
03:18:06,520 --> 03:18:08,160
RIGHT?

4952
03:18:08,160 --> 03:18:12,040
SO WE DECIDED TO KIND OF TAKE A

4953
03:18:12,040 --> 03:18:17,080
LITTLE BIT, YOU KNOW, A MORE, AS

4954
03:18:17,080 --> 03:18:18,960
EMMELINE DESCRIBED, A BROADER

4955
03:18:18,960 --> 03:18:22,320
APPROACH THAT WOULD NOT CREATE

4956
03:18:22,320 --> 03:18:23,640
BRAND NEW INITIATIVES THAT WOULD

4957
03:18:23,640 --> 03:18:31,440
BE DIFFICULT FOR PEOPLE TO DO 

4958
03:18:31,440 --> 03:18:35,560
FROM EVERY POSSIBLE ANGLE.

4959
03:18:35,560 --> 03:18:37,520
>> ANY OTHER QUESTIONS ABOUT

4960
03:18:37,520 --> 03:18:38,160
CURRENT FUNDING OPPORTUNITY

4961
03:18:38,160 --> 03:18:38,800
ANNOUNCEMENTS AVAILABLE THAT

4962
03:18:38,800 --> 03:18:40,360
PEOPLE HAVE?

4963
03:18:40,360 --> 03:18:42,640
THERE ARE A LOT I THINK IS THE

4964
03:18:42,640 --> 03:18:43,440
SHORT STORY.

4965
03:18:43,440 --> 03:18:44,520
TAKE HOME THAT MESSAGE.

4966
03:18:44,520 --> 03:18:52,640
IF YOU HAVE AN IDEA RELATED TO 

4967
03:18:52,640 --> 03:18:54,040
PAIN RESEARCH WE'RE INTERESTED.

4968
03:18:54,040 --> 03:18:55,240
YOU CAN CERTAINLY FIND ONE

4969
03:18:55,240 --> 03:18:56,880
THAT'S AVAILABLE TO YOU.

4970
03:18:56,880 --> 03:18:58,080
THANK YOU VERY MUCH, DR.

4971
03:18:58,080 --> 03:18:58,400
EDWARDS.

4972
03:18:58,400 --> 03:19:01,920
WE'RE NOW GOING TO SHIFT TO THE

4973
03:19:01,920 --> 03:19:07,360
PRESENTATION BY DR. ROBIN

4974
03:19:07,360 --> 03:19:08,960
BOINEAU, REQUIRED TRIENNIAL

4975
03:19:08,960 --> 03:19:13,960
REPORT ON CLINICAL STUDIES.

4976
03:19:13,960 --> 03:19:14,320
DR. BOINEAU?

4977
03:19:14,320 --> 03:19:15,960
>>  THANK YOU.

4978
03:19:15,960 --> 03:19:22,880
I'M GOING TO SHARE MY SCREEN.

4979
03:19:22,880 --> 03:19:25,760
IS THAT SHOWING UP FOR YOU ALL?

4980
03:19:25,760 --> 03:19:27,920
>> YES.

4981
03:19:27,920 --> 03:19:31,760
>> LET ME PUT IT IN THE -- ALL

4982
03:19:31,760 --> 03:19:32,280
RIGHT.

4983
03:19:32,280 --> 03:19:34,280
I'M ROBIN BOINEAU, DIRECTOR OF

4984
03:19:34,280 --> 03:19:35,880
OFFICE OF CLINICAL REGULATORY

4985
03:19:35,880 --> 03:19:37,880
AFFAIRS, I'M GIVING THE

4986
03:19:37,880 --> 03:19:39,640
TRIENNIAL REPORT, IT HAS TO BE

4987
03:19:39,640 --> 03:19:42,760
GIVEN EVERY THREE YEARS.

4988
03:19:42,760 --> 03:19:45,200
THE TOPIC IS INCLUSION OF --

4989
03:19:45,200 --> 03:19:47,600
FOCUS OF THE PRESENTATION IS

4990
03:19:47,600 --> 03:19:50,840
INCLUSION OF WOMEN AND 

4991
03:19:50,840 --> 03:19:53,080
MINORITIES IN CLINICAL RESEARCH.

4992
03:19:53,080 --> 03:19:53,760
IT'S SOMETHING THAT'S GROWN OUT

4993
03:19:53,760 --> 03:19:55,720
OF THE WOMEN'S HEALTH MOVEMENT

4994
03:19:55,720 --> 03:19:58,760
AND THEN BECAME A POLICY IN 1986

4995
03:19:58,760 --> 03:20:01,800
REQUIRING INCLUSION OF WOMEN IN

4996
03:20:01,800 --> 03:20:02,920
CLINICAL RESEARCH AND PUBLISHED

4997
03:20:02,920 --> 03:20:04,960
IN 1987.

4998
03:20:04,960 --> 03:20:06,520
CONGRESS MADE THE POLICY AND OF

4999
03:20:06,520 --> 03:20:09,320
AND PUBLIC LAW THROUGH A SECONDS

5000
03:20:09,320 --> 03:20:21,000
OF NIH REVITALIZATION ACT OF 

5001
03:20:21,000 --> 03:20:21,200
1993.

5002
03:20:21,200 --> 03:20:25,160
WHY IS MY -- NIH DIRECTOR IS

5003
03:20:25,160 --> 03:20:30,920
REQUIRED TO PROVIDE REPORT TO

5004
03:20:30,920 --> 03:20:32,160
CONGRESS, STATE OF RESEARCH,

5005
03:20:32,160 --> 03:20:36,040
THIS IS PART OF THE REPORT OF

5006
03:20:36,040 --> 03:20:38,120
HOW WE'RE DOING WITH INCLUSION

5007
03:20:38,120 --> 03:20:39,760
OF WOMEN AND MINORITIES IN

5008
03:20:39,760 --> 03:20:42,480
CLINICAL RESEARCH.

5009
03:20:42,480 --> 03:20:45,560
KEEP IN MIND ENROLLING SUBJECTS

5010
03:20:45,560 --> 03:20:48,160
IN RESEARCH, YOU'RE NOT REQUIRED

5011
03:20:48,160 --> 03:20:50,440
TO ENROLL WHAT IS IN THE U.S.

5012
03:20:50,440 --> 03:20:51,760
CENSUS BUT TO CONDUCT RESEARCH

5013
03:20:51,760 --> 03:20:53,800
SO THAT THE FINDINGS WILL BE

5014
03:20:53,800 --> 03:20:56,360
GENERALIZABLE TO THE U.S.

5015
03:20:56,360 --> 03:20:56,800
POPULATION.

5016
03:20:56,800 --> 03:20:59,200
IF YOU'RE STUDYING A SPECIFIC

5017
03:20:59,200 --> 03:21:00,200
DISEASE PROCESS, YOU'RE GOING TO

5018
03:21:00,200 --> 03:21:01,840
WANT TO LOOK AT WHAT THE

5019
03:21:01,840 --> 03:21:04,680
INCIDENCE OF THAT DISEASE IS IN

5020
03:21:04,680 --> 03:21:10,360
THE U.S. POPULATION TO HELP YOU

5021
03:21:10,360 --> 03:21:12,000
DEFINE YOUR POPULATION.

5022
03:21:12,000 --> 03:21:13,640
SO WHERE DO WE GET THIS DATA

5023
03:21:13,640 --> 03:21:18,680
YOU'RE LOOKING AT  TODAY?

5024
03:21:18,680 --> 03:21:26,240
IF YOU'RE AN INVESTIGATOR YOU

5025
03:21:26,240 --> 03:21:27,640
PROVIDE INCLUSION ENROLLMENT

5026
03:21:27,640 --> 03:21:28,360
REPORT.

5027
03:21:28,360 --> 03:21:31,480
THIS IS FROM FY 19, 20, 21.

5028
03:21:31,480 --> 03:21:35,320
THIS HAS THE OF DOMESTIC

5029
03:21:35,320 --> 03:21:35,600
ENROLLMENT.

5030
03:21:35,600 --> 03:21:36,520
INVESTIGATORS ARE STUDIES

5031
03:21:36,520 --> 03:21:38,560
ENROLLING IN CANADA OR OTHER

5032
03:21:38,560 --> 03:21:40,440
COUNTRIES, THAT DATA IS NOT

5033
03:21:40,440 --> 03:21:42,040
INCLUDED HERE.

5034
03:21:42,040 --> 03:21:43,800
IT'S FOR EXTRAMURAL AND

5035
03:21:43,800 --> 03:21:46,240
INTRAMURAL RESEARCH PROJECTS.

5036
03:21:46,240 --> 03:21:50,040
AND THE CLINICAL RESEARCH DATA

5037
03:21:50,040 --> 03:21:53,160
IS FROM THE 2018 DATA, REPORTED

5038
03:21:53,160 --> 03:21:56,200
IN THE 2019 ANNUAL REPORT.

5039
03:21:56,200 --> 03:22:01,160
THE 2020 DATA YOU'RE SEEING 2019

5040
03:22:01,160 --> 03:22:01,440
ENROLLMENT.

5041
03:22:01,440 --> 03:22:02,760
AND THEN ONE TO KEEP IN MIND

5042
03:22:02,760 --> 03:22:05,600
WHEN WE LOOK AT THE DATA

5043
03:22:05,600 --> 03:22:07,480
REPORTED AS 2021, DATA THAT CAME

5044
03:22:07,480 --> 03:22:09,120
IN IN 2020.

5045
03:22:09,120 --> 03:22:14,400
SO WE START IN OCTOBER, OF 2019,

5046
03:22:14,400 --> 03:22:17,360
AND WE GO THROUGH SEPTEMBER OF

5047
03:22:17,360 --> 03:22:17,600
2020.

5048
03:22:17,600 --> 03:22:22,840
SO ABOUT SIX MONTHS OF THAT DATA

5049
03:22:22,840 --> 03:22:25,480
WE WERE NOT AFFECTED VERY

5050
03:22:25,480 --> 03:22:26,880
GREATLY BY COVID.

5051
03:22:26,880 --> 03:22:30,960
BUT THE SECOND SIX MONTHS OF

5052
03:22:30,960 --> 03:22:34,880
2020, YOU KNOW, WE HAD MORE

5053
03:22:34,880 --> 03:22:37,840
IMPACT OF COVID-19 ON STUDY

5054
03:22:37,840 --> 03:22:38,240
RECRUITMENT.

5055
03:22:38,240 --> 03:22:38,720
OKAY.

5056
03:22:38,720 --> 03:22:40,480
SO HOW MANY STUDIES ARE WE

5057
03:22:40,480 --> 03:22:42,400
LOOKING AT FOR THIS REPORT

5058
03:22:42,400 --> 03:22:42,840
TODAY?

5059
03:22:42,840 --> 03:22:45,720
SO, THE ONE TO FOCUS ON IS THE

5060
03:22:45,720 --> 03:22:48,760
NUMBER OF STUDIES THAT HAD

5061
03:22:48,760 --> 03:22:49,080
ENROLLMENT.

5062
03:22:49,080 --> 03:22:52,400
SO IN 2019, THERE WERE 102.

5063
03:22:52,400 --> 03:22:56,360
IN 2020, 113.

5064
03:22:56,360 --> 03:22:57,760
AND 2021, 123.

5065
03:22:57,760 --> 03:23:01,760
AND THE PHASE 3 STUDIES THERE

5066
03:23:01,760 --> 03:23:03,560
WERE TWO, IN 2019.

5067
03:23:03,560 --> 03:23:07,320
TEN IN 2020. 

5068
03:23:07,320 --> 03:23:10,200
AND AGAIN 10 IN 2021.

5069
03:23:10,200 --> 03:23:14,560
SO THIS IS ALL NCCIH INTRAMURAL

5070
03:23:14,560 --> 03:23:16,560
AND EXTRAMURAL DEFINED CLINICAL

5071
03:23:16,560 --> 03:23:20,480
RESEARCH IN 2019.

5072
03:23:20,480 --> 03:23:20,800
OKAY.

5073
03:23:20,800 --> 03:23:23,200
SO, THE THINGS TO NOTICE HERE

5074
03:23:23,200 --> 03:23:27,720
ARE IN OF WE HAD ALMOST 10,000

5075
03:23:27,720 --> 03:23:29,160
PATIENTS ENROLLED, ALL OUR

5076
03:23:29,160 --> 03:23:32,720
STUDIES, IN 2019 THAT WENT UP TO

5077
03:23:32,720 --> 03:23:36,000
15 OR 16,000, UP TO 50,000

5078
03:23:36,000 --> 03:23:37,400
ALMOST IN 2021.

5079
03:23:37,400 --> 03:23:39,080
WHAT WERE THE DISTRIBUTIONS OF

5080
03:23:39,080 --> 03:23:43,120
WOMEN AND MEN?

5081
03:23:43,120 --> 03:23:47,280
SO, SLIGHTLY OVER 50% IN 2019.

5082
03:23:47,280 --> 03:23:51,680
AND CLOSER TO 50/50 IN 2020,

5083
03:23:51,680 --> 03:23:53,160
SLIGHTLY LESS IN 2021.

5084
03:23:53,160 --> 03:23:57,120
SO THEN WE LOOK AT MINORITY

5085
03:23:57,120 --> 03:23:57,440
ENROLLMENT.

5086
03:23:57,440 --> 03:24:00,080
SO THIS IS ALSO BOTH INTRAMURAL

5087
03:24:00,080 --> 03:24:01,360
AND EXTRAMURAL DATA.

5088
03:24:01,360 --> 03:24:04,640
SO THE SAME NUMBERS FOR TOTAL

5089
03:24:04,640 --> 03:24:06,400
ENROLLMENT, AND MINORITY

5090
03:24:06,400 --> 03:24:10,760
ENROLLMENT WE'VE GOT 25% OF THE

5091
03:24:10,760 --> 03:24:15,720
TOTAL ENROLLMENT IN 2019, 26% IN

5092
03:24:15,720 --> 03:24:17,560
2020, AND 27% IN 2021.

5093
03:24:17,560 --> 03:24:21,320
AND THEN LOOKING AT HISPANIC AND

5094
03:24:21,320 --> 03:24:25,240
LATINO VERSUS NON-HISPANIC AND

5095
03:24:25,240 --> 03:24:28,720
SO NON-HISPANIC OBVIOUSLY

5096
03:24:28,720 --> 03:24:30,640
INCLUDES MINORITY GROUPS THAT

5097
03:24:30,640 --> 03:24:32,040
ARE NOT HISPANIC, RIGHT?

5098
03:24:32,040 --> 03:24:33,880
SO ETHNICITY VERSUS RACE.

5099
03:24:33,880 --> 03:24:40,120
AND SO WE HAD A VERY SMALL

5100
03:24:40,120 --> 03:24:46,240
PROPORTION OF HISPANIC SUBJECTS

5101
03:24:46,240 --> 03:24:49,320
ENROLLED IN 2019, 2020, 2021

5102
03:24:49,320 --> 03:24:50,160
COMPARED TO NON-HISPANIC

5103
03:24:50,160 --> 03:24:50,480
POPULATION.

5104
03:24:50,480 --> 03:24:53,760
AND SO NOW WE'RE GOING TO GO AND

5105
03:24:53,760 --> 03:24:56,440
LOOK AT TOTAL ENROLLMENT IN

5106
03:24:56,440 --> 03:24:59,720
PHASE 3 CLINICAL TRIALS BY SEX.

5107
03:24:59,720 --> 03:25:03,400
SO, THE NUMBERS OF ENROLLMENT

5108
03:25:03,400 --> 03:25:04,840
ARE DIFFERENT, SO IN 2019, AS

5109
03:25:04,840 --> 03:25:07,160
YOU MAY RECALL, WE HAD TWO

5110
03:25:07,160 --> 03:25:09,840
STUDIES THAT WERE PHASE 3

5111
03:25:09,840 --> 03:25:12,960
STUDIES THAT WERE RECRUITING, WE

5112
03:25:12,960 --> 03:25:15,400
HAD 268 PATIENTS ENROLLED IN

5113
03:25:15,400 --> 03:25:16,280
2019.

5114
03:25:16,280 --> 03:25:19,160
WE HAD TEN STUDIES ENROLLING IN

5115
03:25:19,160 --> 03:25:24,560
REPORTING FOR 2020 DATA.

5116
03:25:24,560 --> 03:25:27,040
1476 PATIENTS.

5117
03:25:27,040 --> 03:25:33,760
AND IN 2021, THAT WENT DOWN,

5118
03:25:33,760 --> 03:25:34,400
1169.

5119
03:25:34,400 --> 03:25:36,160
PROPORTIONS OF FEMALE TO MALE IS

5120
03:25:36,160 --> 03:25:38,000
NOT THE SAME WE SAW OVERALL

5121
03:25:38,000 --> 03:25:45,880
WHERE WE KIND OF HAD CLOSER TO

5122
03:25:45,880 --> 03:25:49,960
50/ 50 OVERALL. 

5123
03:25:49,960 --> 03:25:58,320
WOMEN TO MEN TENDING TO 1/ 3 TO

5124
03:25:58,320 --> 03:25:58,760
2/3.

5125
03:25:58,760 --> 03:26:01,960
AND CLINICAL DATA, SAME

5126
03:26:01,960 --> 03:26:03,320
ENROLLMENT SIZE, SAME POPULATION

5127
03:26:03,320 --> 03:26:05,720
AS THE LAST SLIDE.

5128
03:26:05,720 --> 03:26:07,560
HERE YOU'LL SEE MINORITY, IN THE

5129
03:26:07,560 --> 03:26:15,240
SMALL SAMPLE, IN TWO STUDIES.

5130
03:26:15,240 --> 03:26:18,640
32% IN MINORITIES IN 2020, AND

5131
03:26:18,640 --> 03:26:22,480
45% IN 2021.

5132
03:26:22,480 --> 03:26:23,840
AND THEN HISPANIC/NON-HISPANIC,

5133
03:26:23,840 --> 03:26:27,040
SMALL NUMBERS THE FIRST YEAR,

5134
03:26:27,040 --> 03:26:37,680
AND SPLIT WAS 28/80, 40/74.

5135
03:26:37,680 --> 03:26:38,680
AND 67%.

5136
03:26:38,680 --> 03:26:40,640
AND THIS IS -- I WANTED TO SHOW

5137
03:26:40,640 --> 03:26:44,680
A LOOK AT WHAT'S GOING ON IN OUR

5138
03:26:44,680 --> 03:26:49,480
INTRAMURAL PORTFOLIO.

5139
03:26:49,480 --> 03:26:53,520
TOTAL ENROLLMENT WAS 344 IN

5140
03:26:53,520 --> 03:26:54,240
2009.

5141
03:26:54,240 --> 03:27:00,360
1,407 IN 2020. 

5142
03:27:00,360 --> 03:27:03,160
AND 2021, 2102 SUBJECTS.

5143
03:27:03,160 --> 03:27:07,280
MINORITY 64% IN 2019.

5144
03:27:07,280 --> 03:27:09,360
32% IN 2020.

5145
03:27:09,360 --> 03:27:12,200
UP HIGHER RATE, 38% IN 2021.

5146
03:27:12,200 --> 03:27:20,760
AND SPLIT TO MALE TO FEMALE, WAS

5147
03:27:20,760 --> 03:27:24,480
56% WOMEN, 45%, AND 45%

5148
03:27:24,480 --> 03:27:25,960
RESPECTIVELY FOR 2019, 2020,

5149
03:27:25,960 --> 03:27:26,160
2021.

5150
03:27:26,160 --> 03:27:28,160
AND THEN AS I SAID AT THE TOP

5151
03:27:28,160 --> 03:27:34,280
WE'RE NOT TRYING TO COMPARE TO

5152
03:27:34,280 --> 03:27:36,160
CENSUS DATA, WHEN PEOPLE DECIDE

5153
03:27:36,160 --> 03:27:38,560
WHAT THEIR GOAL IS FOR

5154
03:27:38,560 --> 03:27:39,160
ENROLLING.

5155
03:27:39,160 --> 03:27:40,840
TARGETS ARE FOR ENROLLING

5156
03:27:40,840 --> 03:27:41,160
MINORITIES.

5157
03:27:41,160 --> 03:27:45,880
BUT I THINK IT'S HELPFUL TO SEE,

5158
03:27:45,880 --> 03:27:47,720
FROM THE 2020 CENSUS, SLIGHTLY

5159
03:27:47,720 --> 03:27:50,320
MORE THAN HALF THE POPULATION

5160
03:27:50,320 --> 03:27:53,200
WAS WOMEN.

5161
03:27:53,200 --> 03:27:56,320
AND OUR NUMBERS OVER TIME HAVE

5162
03:27:56,320 --> 03:28:00,760
KIND OF REFLECTED THAT. 

5163
03:28:00,760 --> 03:28:03,640
WE DO HAVE SLIGHTLY HIGHER THAN

5164
03:28:03,640 --> 03:28:05,000
THAT, MINORITIES 24%.

5165
03:28:05,000 --> 03:28:09,680
NUMBERS ARE SIMILAR TO THAT AS

5166
03:28:09,680 --> 03:28:09,920
WELL.

5167
03:28:09,920 --> 03:28:10,480
EXCUSE ME.

5168
03:28:10,480 --> 03:28:14,040
BUT I DO WANT TO MAKE THE

5169
03:28:14,040 --> 03:28:15,360
EMPHASIS THAT, NUMBER ONE, THE

5170
03:28:15,360 --> 03:28:23,320
THING TO KEEP IN MIND IS

5171
03:28:23,320 --> 03:28:24,400
COVID-19 EFFECTS ON STUDY

5172
03:28:24,400 --> 03:28:25,760
RECRUITMENT IS SOMETHING WE MAY

5173
03:28:25,760 --> 03:28:28,560
HAVE SEEN IN 2021, AS WE SAW

5174
03:28:28,560 --> 03:28:30,560
THAT THE DROP IN CLINICAL TRIAL

5175
03:28:30,560 --> 03:28:31,440
ENROLLMENT NUMBERS, AND THAT

5176
03:28:31,440 --> 03:28:33,840
REFLECTED WHAT WE WERE SEEING AS

5177
03:28:33,840 --> 03:28:34,800
WE WORKED WITH INVESTIGATORS

5178
03:28:34,800 --> 03:28:39,880
THAT WERE OUT IN THE FIELD 

5179
03:28:39,880 --> 03:28:42,080
HAVING TO STOP STUDIES, AND WORK

5180
03:28:42,080 --> 03:28:43,480
ON ISSUES RELATED TO COVID

5181
03:28:43,480 --> 03:28:46,840
BEFORE THEY WERE ABLE TO

5182
03:28:46,840 --> 03:28:49,360
REINITIATE CLINICAL STUDIES.

5183
03:28:49,360 --> 03:28:52,760
WE ARE -- WE SEE AT NCCIH AS

5184
03:28:52,760 --> 03:28:55,960
RECRUITMENT OF MINORITIES AS A 

5185
03:28:55,960 --> 03:28:58,200
VERY IMPORTANT PART OF OUR GOALS

5186
03:28:58,200 --> 03:29:01,080
AND EFFORTS AT BOTH AT NIH AND

5187
03:29:01,080 --> 03:29:04,000
NCCIH, AS PART OF THAT.

5188
03:29:04,000 --> 03:29:06,640
THERE WAS AN NCCIH HOT TOPIC

5189
03:29:06,640 --> 03:29:08,480
WEBINAR ENGAGING DIVERSE

5190
03:29:08,480 --> 03:29:09,480
COMMUNITIES AND COMPLEMENTARY

5191
03:29:09,480 --> 03:29:10,760
INTEGRATIVE HEALTH, IF YOU

5192
03:29:10,760 --> 03:29:12,080
WEREN'T ABLE TO ATTEND THAT

5193
03:29:12,080 --> 03:29:14,560
THERE WAS A RECORDING OF THAT

5194
03:29:14,560 --> 03:29:20,160
TWO-HOUR PRESENTATION ONLINE. 

5195
03:29:20,160 --> 03:29:21,520
THERE'S A LINK THERE.

5196
03:29:21,520 --> 03:29:22,960
IT WAS MENTIONED EARLIER TODAY

5197
03:29:22,960 --> 03:29:27,040
THE NIH UNITE PROGRAM THAT IS

5198
03:29:27,040 --> 03:29:28,120
LOOKING TO EXPAND.

5199
03:29:28,120 --> 03:29:34,920
A LOT OF THE EFFORTS TO ADDRESS

5200
03:29:34,920 --> 03:29:36,320
STRUCTURAL RACISM AT NIH, AND

5201
03:29:36,320 --> 03:29:40,560
ENCOURAGE YOU TO TAKE A LOOK AT

5202
03:29:40,560 --> 03:29:43,600
THAT TO SEE WHAT THE THINGS ARE

5203
03:29:43,600 --> 03:29:47,240
THAT ARE AVAILABLE TO THE NIH'S

5204
03:29:47,240 --> 03:29:49,560
SETTING UP TO ASSIST WITH THOSE

5205
03:29:49,560 --> 03:29:52,760
EFFORTS WHICH ARE OBVIOUSLY

5206
03:29:52,760 --> 03:29:54,360
IMPORTANT FOR US AS A COMMUNITY

5207
03:29:54,360 --> 03:29:55,680
IN THE UNITED STATES.

5208
03:29:55,680 --> 03:29:57,640
THE OTHER THING IS WE CONTINUE

5209
03:29:57,640 --> 03:29:58,280
TO SUPPORT INCREASED

5210
03:29:58,280 --> 03:30:02,920
PARTICIPATION OF WOMEN AND

5211
03:30:02,920 --> 03:30:04,320
MINORITIES IN NCCIH-FUNDED

5212
03:30:04,320 --> 03:30:05,160
STUDIES.

5213
03:30:05,160 --> 03:30:09,840
I WANT TO SAY THANK YOU FOR THE

5214
03:30:09,840 --> 03:30:19,360
HEAVY LIFTING, DENICE SIMMONS,

5215
03:30:19,360 --> 03:30:23,080
AND CHRISTINE WISHOFF, IN MY

5216
03:30:23,080 --> 03:30:25,720
GROUP, A VALUABLE JOB IN

5217
03:30:25,720 --> 03:30:27,000
ANALYZING AND PUTTING THIS

5218
03:30:27,000 --> 03:30:28,560
MATERIAL TOGETHER FOR THE

5219
03:30:28,560 --> 03:30:30,400
PRESENTATION TODAY.

5220
03:30:30,400 --> 03:30:32,600
THERE'S ALSO A WEBSITE THAT'S

5221
03:30:32,600 --> 03:30:39,840
PUBLICLY AVAILABLE WITH NIH DATA

5222
03:30:39,840 --> 03:30:44,320
THAT IS LOOKING AT DISEASE,

5223
03:30:44,320 --> 03:30:48,040
DISEASE OR CONDITION, HOW WE'RE

5224
03:30:48,040 --> 03:30:49,440
RECRUITING AT NIH.

5225
03:30:49,440 --> 03:30:50,680
THERE'S A WEBSITE, YOU CAN

5226
03:30:50,680 --> 03:30:52,760
SEARCH BY THE CONDITION, ASTHMA,

5227
03:30:52,760 --> 03:30:56,000
ET CETERA, AND SEE PROPORTION OF

5228
03:30:56,000 --> 03:30:56,880
WOMEN OR MEN.

5229
03:30:56,880 --> 03:31:00,600
ALSO CAN SORT BY ETHNICITY AND

5230
03:31:00,600 --> 03:31:00,800
RACE.

5231
03:31:00,800 --> 03:31:04,960
AND THE DATA IS AVAILABLE FOR

5232
03:31:04,960 --> 03:31:06,480
SUBJECTS ENROLLED IN FY 2018.

5233
03:31:06,480 --> 03:31:08,160
THAT'S MY PRESENTATION TODAY.

5234
03:31:08,160 --> 03:31:15,480
HAPPY TO ANSWER ANY QUESTIONS 

5235
03:31:15,480 --> 03:31:17,000
YOU MAY HAVE.

5236
03:31:17,000 --> 03:31:18,440
>> THANK YOU.

5237
03:31:18,440 --> 03:31:21,560
>> CERTAINLY COVID HAS HAD

5238
03:31:21,560 --> 03:31:22,800
DRAMATIC EFFECT ON A LOT OF

5239
03:31:22,800 --> 03:31:24,200
PEOPLE IN TERMS OF RECRUITMENT

5240
03:31:24,200 --> 03:31:27,440
AND EVERYTHING ELSE WITH 

5241
03:31:27,440 --> 03:31:30,680
INSTITUTIONS BEING SHUT DOWN.

5242
03:31:30,680 --> 03:31:31,760
GENERALLY, FUNDS ARE BEING

5243
03:31:31,760 --> 03:31:34,400
ALLOCATED TO RECOVER SOME GAPS

5244
03:31:34,400 --> 03:31:36,360
AND EXTEND RECRUITMENT.

5245
03:31:36,360 --> 03:31:40,080
HOW IS NCCIH GOING TO HANDLE

5246
03:31:40,080 --> 03:31:41,320
LOWER THAN ANTICIPATED

5247
03:31:41,320 --> 03:31:43,560
ENROLLMENT THAT'S PRETTY MUCH

5248
03:31:43,560 --> 03:31:50,440
DUE SPECIFICALLY TO COVID, IN 

5249
03:31:50,440 --> 03:31:51,160
TERMS OF ONGOING EXPERIMENTS?

5250
03:31:51,160 --> 03:31:52,800
>> I DON'T KNOW IF EMMELINE

5251
03:31:52,800 --> 03:31:54,520
WANTS TO FOLLOW UP.

5252
03:31:54,520 --> 03:31:55,880
I'VE BEEN THE PROJECT SCIENTIST

5253
03:31:55,880 --> 03:31:58,960
ON A LOT OF LARGE STUDIES, AND

5254
03:31:58,960 --> 03:32:00,320
CONVERSATIONS WITH INVESTIGATORS

5255
03:32:00,320 --> 03:32:01,960
AT THE BEGINNING WAS THAT WE

5256
03:32:01,960 --> 03:32:05,320
ANTICIPATE THIS IS GOING TO

5257
03:32:05,320 --> 03:32:07,320
BE -- IT'S VERY BROAD, AND VERY

5258
03:32:07,320 --> 03:32:09,320
DEEP, THE NUMBER OF

5259
03:32:09,320 --> 03:32:10,800
INVESTIGATORS THAT ARE GOING TO

5260
03:32:10,800 --> 03:32:15,280
BE AFFECTED BY THIS.

5261
03:32:15,280 --> 03:32:17,680
WE DON'T ANTICIPATE WE COULD

5262
03:32:17,680 --> 03:32:19,200
POSSIBLY HAVE THE MONEY TO

5263
03:32:19,200 --> 03:32:21,360
RECRUIT FOR THAT.

5264
03:32:21,360 --> 03:32:23,040
SO IT'S IMPORTANT, YOU KNOW,

5265
03:32:23,040 --> 03:32:24,320
WHEN WE SAW THIS HAPPENING TO

5266
03:32:24,320 --> 03:32:26,760
SEE WHAT YOU CAN DO TO SAVE

5267
03:32:26,760 --> 03:32:27,200
FUNDS, RIGHT?

5268
03:32:27,200 --> 03:32:29,520
AND I THINK THE OTHER THING THAT

5269
03:32:29,520 --> 03:32:35,080
WE ALWAYS DO IN WORKING WITH

5270
03:32:35,080 --> 03:32:37,160
INVESTIGATORS IS SAY WHAT IS

5271
03:32:37,160 --> 03:32:38,920
YOUR MAIN QUESTION, WHAT CAN YOU

5272
03:32:38,920 --> 03:32:42,080
DO TO MAKE SURE YOU'RE ANSWERING

5273
03:32:42,080 --> 03:32:42,960
YOUR PRIMARY AIM?

5274
03:32:42,960 --> 03:32:45,600
AND WHAT DO YOU HAVE

5275
03:32:45,600 --> 03:32:51,760
FUNDING-WISE TO HELP WITH THAT?

5276
03:32:51,760 --> 03:32:54,880
WE DO HAVE FUNDS TO HELP FOLKS

5277
03:32:54,880 --> 03:32:56,760
THAT HAVE -- DON'T HAVE ENOUGH

5278
03:32:56,760 --> 03:32:57,080
FUNDS.

5279
03:32:57,080 --> 03:32:59,080
THERE ARE SOME FUNDS THAT COME

5280
03:32:59,080 --> 03:33:00,160
IN.

5281
03:33:00,160 --> 03:33:02,720
AS YOU CAN IMAGINE, IT COULDN'T

5282
03:33:02,720 --> 03:33:04,080
POSSIBLY COVER EVERY NEED.

5283
03:33:04,080 --> 03:33:06,280
AND SO WHAT WE'RE DOING IS AS

5284
03:33:06,280 --> 03:33:08,000
PEOPLE COME IN, AND I THINK THE

5285
03:33:08,000 --> 03:33:10,080
OTHER THING IS PEOPLE ARE GOING

5286
03:33:10,080 --> 03:33:12,240
TO START ASKING, AS THEY RUN OUT

5287
03:33:12,240 --> 03:33:13,480
OF MONEY, RIGHT?

5288
03:33:13,480 --> 03:33:15,880
IF THEY HAVE A STUDY THAT'S

5289
03:33:15,880 --> 03:33:18,040
THREE YEARS LONG FROM, YOU KNOW,

5290
03:33:18,040 --> 03:33:19,200
OR FIVE YEARS LONG, THEY ARE TWO

5291
03:33:19,200 --> 03:33:20,880
OR THREE YEARS INTO THE STUDY,

5292
03:33:20,880 --> 03:33:22,440
DEPENDS WHEN THEY ARE GOING TO

5293
03:33:22,440 --> 03:33:25,680
START NEEDING MORE.

5294
03:33:25,680 --> 03:33:26,160
REGULAR CONVERSATION.

5295
03:33:26,160 --> 03:33:29,080
WHAT CAN YOU DO WITH THE MONEY

5296
03:33:29,080 --> 03:33:30,160
YOU HAVE?

5297
03:33:30,160 --> 03:33:31,560
AND THEN WE CAN HELP YOU LOOK

5298
03:33:31,560 --> 03:33:33,640
AND SEE WHAT ARE THE OPTIONS.

5299
03:33:33,640 --> 03:33:36,320
YOU KNOW, ARE YOU ABLE TO

5300
03:33:36,320 --> 03:33:37,160
COMPLETE THE STUDY?

5301
03:33:37,160 --> 03:33:38,840
ONE OF THE THINGS WE SAW WAS A

5302
03:33:38,840 --> 03:33:44,840
LOT OF PEOPLE WERE ABLE TO

5303
03:33:44,840 --> 03:33:45,600
TRANSITION TO REMOTE

5304
03:33:45,600 --> 03:33:46,800
INTERVENTIONS, AND WERE ABLE TO

5305
03:33:46,800 --> 03:33:50,200
FIND COST SAVINGS THAT WAY.

5306
03:33:50,200 --> 03:33:55,680
I THINK IT'S BEEN A HEAVY LIFT

5307
03:33:55,680 --> 03:33:56,960
FOR THE INVESTIGATIVE COMMUNITY,

5308
03:33:56,960 --> 03:33:58,400
AND WE'RE HERE TO HELP.

5309
03:33:58,400 --> 03:34:01,240
AND SO IT'S GOOD TO KNOW AS WELL

5310
03:34:01,240 --> 03:34:03,640
AS FAR IN ADVANCE AS POSSIBLE

5311
03:34:03,640 --> 03:34:06,600
WHAT THE ISSUES ARE, AND HAPPY

5312
03:34:06,600 --> 03:34:08,560
TO HELP WALK THROUGH WHAT THAT

5313
03:34:08,560 --> 03:34:08,760
IS.

5314
03:34:08,760 --> 03:34:10,360
EMMELINE, DID YOU HAVE SOMETHING

5315
03:34:10,360 --> 03:34:11,680
TO ADD TO THAT?

5316
03:34:11,680 --> 03:34:15,600
>> YEAH, I'LL JUST ADD THIS HAS

5317
03:34:15,600 --> 03:34:17,320
BEEN REALLY AN ONGOING

5318
03:34:17,320 --> 03:34:19,200
CONVERSATION BETWEEN OUR PROGRAM

5319
03:34:19,200 --> 03:34:21,760
STAFF AND THE INVESTIGATORS,

5320
03:34:21,760 --> 03:34:25,320
AND, YOU KNOW, WE'VE REALLY HAD

5321
03:34:25,320 --> 03:34:27,760
MAXIMUM FLEXIBILITY BUT WANT TO

5322
03:34:27,760 --> 03:34:28,720
PRESERVE INTEGRITY OF THE

5323
03:34:28,720 --> 03:34:32,280
RESEARCH AND SO, YOU KNOW, A LOT

5324
03:34:32,280 --> 03:34:35,760
OF, YOU KNOW, BRAINSTORMING WITH

5325
03:34:35,760 --> 03:34:37,720
INVESTIGATORS, AS ROBIN

5326
03:34:37,720 --> 03:34:41,680
MENTIONED, GUIDING THEM AND

5327
03:34:41,680 --> 03:34:44,400
COMING UP WITH STRATEGIES TO

5328
03:34:44,400 --> 03:34:48,480
MAXIMIZE WHERE THEY ARE INTO

5329
03:34:48,480 --> 03:34:50,000
THEIR PROJECT AND THAT'S -- I

5330
03:34:50,000 --> 03:34:53,520
MEAN, YOU KNOW, SOME

5331
03:34:53,520 --> 03:34:54,520
INVESTIGATORS WERE VERY

5332
03:34:54,520 --> 03:34:57,720
ENTERPRISING AND WERE ABLE TO

5333
03:34:57,720 --> 03:35:01,720
PIVOT, BUT OTHERS, YOU KNOW,

5334
03:35:01,720 --> 03:35:03,960
REQUIRED MORE WORK, DIFFERENT

5335
03:35:03,960 --> 03:35:07,080
PROGRAM, INVESTIGATORS TO COME

5336
03:35:07,080 --> 03:35:10,160
UP WITH A GOOD STRATEGY TO

5337
03:35:10,160 --> 03:35:13,320
PRESERVE, YOU KNOW, THE RESEARCH

5338
03:35:13,320 --> 03:35:20,240
THAT THEY WERE DOING.

5339
03:35:20,240 --> 03:35:20,760
>> GREAT.

5340
03:35:20,760 --> 03:35:21,960
THANKS.

5341
03:35:21,960 --> 03:35:26,400
>> ANY OTHER QUESTIONS ABOUT THE

5342
03:35:26,400 --> 03:35:35,400
TRIENNIAL REPORT? 

5343
03:35:35,400 --> 03:35:37,320
>> OKAY, THANK YOU ALL.

5344
03:35:37,320 --> 03:35:38,840
>> THANK YOU, EVERYONE.

5345
03:35:38,840 --> 03:35:44,440
WE'RE NOW GOING TO GO TO A

5346
03:35:44,440 --> 03:35:47,040
RECOGNITION CEREMONY FOR THOSE

5347
03:35:47,040 --> 03:35:49,920
MEMBERS WHOSE TERMS HAVE EITHER

5348
03:35:49,920 --> 03:35:53,160
ALREADY RECENTLY CONCLUDED OR AS

5349
03:35:53,160 --> 03:36:00,320
IN DR. TIMERMAN'S CASE ARE

5350
03:36:00,320 --> 03:36:01,240
CONCLUDING TODAY.

5351
03:36:01,240 --> 03:36:03,000
DR. LANGEVIN, WOULD YOU LIKE TO

5352
03:36:03,000 --> 03:36:03,760
LEAD US?

5353
03:36:03,760 --> 03:36:09,160
IN ADDITION TO DR. TIMERMAN,

5354
03:36:09,160 --> 03:36:10,960
DOCTORS ANDERSON, AND YEY ARE ON

5355
03:36:10,960 --> 03:36:13,920
THIS CALL NOW.

5356
03:36:13,920 --> 03:36:15,120
UNFORTUNATELY DR. McMILLAN HAD

5357
03:36:15,120 --> 03:36:18,200
AN INTERNET PROBLEM AND WAS

5358
03:36:18,200 --> 03:36:20,760
UNABLE TO JOIN US.

5359
03:36:20,760 --> 03:36:21,960
LOST HIS INTERNET CONNECTION,

5360
03:36:21,960 --> 03:36:26,480
THE WHOLE REGION, DUE TO A WIND 

5361
03:36:26,480 --> 03:36:27,840
STORM.

5362
03:36:27,840 --> 03:36:28,160
>> OH WOW!

5363
03:36:28,160 --> 03:36:28,520
>> DR. LANGEVIN?

5364
03:36:28,520 --> 03:36:34,440
>>  WELL, IT IS A BITTERSWEET

5365
03:36:34,440 --> 03:36:38,960
MOMENT SAY GOOD-BYE TO FOUR

5366
03:36:38,960 --> 03:36:40,240
WONDERFUL COUNCIL MEMBERS WITH

5367
03:36:40,240 --> 03:36:40,880
US NOW --

5368
03:36:40,880 --> 03:36:44,080
>> I'M OFF CAMERA.

5369
03:36:44,080 --> 03:36:45,840
>> AND NORMALLY IN PERSON, I

5370
03:36:45,840 --> 03:36:48,560
WOULD BE HANDING YOU A

5371
03:36:48,560 --> 03:36:52,360
CERTIFICATE AND I WOULD BE

5372
03:36:52,360 --> 03:36:55,240
THANKING YOU AND SHAKING HANDS.

5373
03:36:55,240 --> 03:36:56,880
IT'S HARD TO BELIEVE WE USED TO

5374
03:36:56,880 --> 03:36:59,520
DO THESE THINGS.

5375
03:36:59,520 --> 03:37:01,960
YOU KNOW, AND SO I WANTED TO AT

5376
03:37:01,960 --> 03:37:03,680
LEAST BEGIN, WHEN I SAY YOUR

5377
03:37:03,680 --> 03:37:05,520
NAME, TURN ON YOUR CAMERA AND WE

5378
03:37:05,520 --> 03:37:09,320
CAN WAVE AT YOU AND SAY THANK

5379
03:37:09,320 --> 03:37:11,200
YOU AND GOOD-BYE.

5380
03:37:11,200 --> 03:37:15,160
FIRST, GLORIA, WHERE ARE YOU?

5381
03:37:15,160 --> 03:37:22,840
ARE WE IN ORDER?

5382
03:37:22,840 --> 03:37:25,320
GLORIA YEH, SHE DROPPED OFF.

5383
03:37:25,320 --> 03:37:29,040
>> CAN YOU SEE ME?

5384
03:37:29,040 --> 03:37:30,280
>> YES.

5385
03:37:30,280 --> 03:37:30,560
>> HELLO!

5386
03:37:30,560 --> 03:37:32,160
>> IT'S BEEN SUCH A PLEASURE

5387
03:37:32,160 --> 03:37:35,320
HAVING YOU ON THE COUNCIL.

5388
03:37:35,320 --> 03:37:36,760
AND WE WANT TO THANK YOU.

5389
03:37:36,760 --> 03:37:40,040
WE WANT TO WISH YOU THE BEST.

5390
03:37:40,040 --> 03:37:43,120
IT'S TOO BAD ONLY PART OF YOUR

5391
03:37:43,120 --> 03:37:47,840
TENURE, AT LEAST SOME WAS IN

5392
03:37:47,840 --> 03:37:48,080
PERSON.

5393
03:37:48,080 --> 03:37:55,760
WE HAD THE MIXED EXPERIENCE.

5394
03:37:55,760 --> 03:37:58,280
>> THANK YOU.

5395
03:37:58,280 --> 03:38:00,040
>> THANK YOU, NCCIH, IT WAS

5396
03:38:00,040 --> 03:38:02,200
REALLY A PLEASURE AND HONOR.

5397
03:38:02,200 --> 03:38:04,760
I OWE SO MUCH TO NCCIH FOR MY

5398
03:38:04,760 --> 03:38:05,400
WHOLE CAREER.

5399
03:38:05,400 --> 03:38:07,960
IT WAS WONDERFUL TO BE ABLE TO

5400
03:38:07,960 --> 03:38:10,960
CONTRIBUTE  BACK TO THE MISSION.

5401
03:38:10,960 --> 03:38:16,600
>> IT WAS GREAT TO HAVE YOU.

5402
03:38:16,600 --> 03:38:17,640
YOUR EXPERTISE CONTRIBUTED

5403
03:38:17,640 --> 03:38:22,080
GREATLY TO OUR COUNCIL. 

5404
03:38:22,080 --> 03:38:24,160
SO THANK YOU. 

5405
03:38:24,160 --> 03:38:26,760
AND NEXT, I DON'T KNOW WHO IS

5406
03:38:26,760 --> 03:38:30,520
NEXT. 

5407
03:38:30,520 --> 03:38:31,560
YOU TELL ME.

5408
03:38:31,560 --> 03:38:35,560
OH, WHERE ARE YOU, BARBARA?

5409
03:38:35,560 --> 03:38:37,360
>>  I'M HERE.

5410
03:38:37,360 --> 03:38:40,320
>> BARBARA TIMERMAN, THANK YOU

5411
03:38:40,320 --> 03:38:41,880
FOR BEING A COUNCIL MEMBER.

5412
03:38:41,880 --> 03:38:44,720
WE APPRECIATE ALL THE EXPERTISE

5413
03:38:44,720 --> 03:38:46,480
THAT YOU GAVE US, AND WE WISH

5414
03:38:46,480 --> 03:38:47,760
YOU THE BEST.

5415
03:38:47,760 --> 03:38:50,640
YOU KNOW, WE'LL MISS YOU.

5416
03:38:50,640 --> 03:38:55,160
>> I WILL MISS YOU TOO.

5417
03:38:55,160 --> 03:38:56,720
I'M ALREADY MISSING YOU.

5418
03:38:56,720 --> 03:39:11,200
THIS HAS BEEN MY SECOND COUNCIL.

5419
03:39:11,200 --> 03:39:13,760
I WAS PART OF THE ORIGINAL

5420
03:39:13,760 --> 03:39:21,720
OFFICE OF ALTERNATIVE MEDICINE

5421
03:39:21,720 --> 03:39:29,520
WITH  JOSEPH JACOBS.

5422
03:39:29,520 --> 03:39:31,360
TODAY I LEARNED A LOT ABOUT

5423
03:39:31,360 --> 03:39:33,920
JOINTS AND WILL RESPECT MY

5424
03:39:33,920 --> 03:39:35,520
JOINTS MUCH MORE.

5425
03:39:35,520 --> 03:39:37,280
SO THANK YOU SO MUCH.

5426
03:39:37,280 --> 03:39:39,680
GOOD LUCK IN THE FUTURE.

5427
03:39:39,680 --> 03:39:40,320
I WILL MISS YOU.

5428
03:39:40,320 --> 03:39:42,080
>> WE WILL MISS YOU TOO.

5429
03:39:42,080 --> 03:39:44,560
THANK YOU VERY, VERY MUCH FOR

5430
03:39:44,560 --> 03:39:47,280
YOUR SERVICE ON OUR COUNCIL.

5431
03:39:47,280 --> 03:39:49,120
WE REALLY APPRECIATE IT.

5432
03:39:49,120 --> 03:40:01,960
>> I SEND KISSES TO ALL. 

5433
03:40:01,960 --> 03:40:02,320
BYE-BYE.

5434
03:40:02,320 --> 03:40:02,760
>> VIRTUAL HUGS.

5435
03:40:02,760 --> 03:40:04,400
>> DR. McMILLAN IS UNABLE TO

5436
03:40:04,400 --> 03:40:05,880
JOIN US.

5437
03:40:05,880 --> 03:40:08,280
>> WE'LL SAY A VIRTUAL GOOD-BYE

5438
03:40:08,280 --> 03:40:10,400
TO DR. JOHN McMILLAN, WHO WAS

5439
03:40:10,400 --> 03:40:13,160
A WONDERFUL COUNCIL MEMBER AS

5440
03:40:13,160 --> 03:40:13,360
WELL.

5441
03:40:13,360 --> 03:40:25,360
WE'LL MISS HIM AS WELL.

5442
03:40:25,360 --> 03:40:26,720
FINALLY, BO ANDERSON.

5443
03:40:26,720 --> 03:40:28,160
WE'LL MISS YOU.

5444
03:40:28,160 --> 03:40:30,560
YOU'VE KEPT US ON OUR TOES

5445
03:40:30,560 --> 03:40:33,720
REGARDING SO MANY THINGS YOU

5446
03:40:33,720 --> 03:40:35,240
WOULD REMIND US OF, WE'RE

5447
03:40:35,240 --> 03:40:36,440
GRATEFUL FOR OUR CONTRIBUTIONS

5448
03:40:36,440 --> 03:40:38,960
TO OUR COUNCIL.

5449
03:40:38,960 --> 03:40:40,920
THANK YOU.

5450
03:40:40,920 --> 03:40:43,760
>> WELL, THANKS SO MUCH, HELENE.

5451
03:40:43,760 --> 03:40:45,320
IT'S BEEN AN HONOR AND

5452
03:40:45,320 --> 03:40:45,760
PRIVILEGE.

5453
03:40:45,760 --> 03:40:48,160
I LOVED ALL THE CONVERSATIONS WE

5454
03:40:48,160 --> 03:40:51,000
HAD AND GETTING TO KNOW NEW

5455
03:40:51,000 --> 03:40:51,760
COLLEAGUES AND RECONNECTING WITH

5456
03:40:51,760 --> 03:40:52,520
OLD COLLEAGUES.

5457
03:40:52,520 --> 03:40:54,840
I WAS VERY INTERESTED IN THE

5458
03:40:54,840 --> 03:40:56,720
CONVERSATION TODAY ABOUT TOUCH

5459
03:40:56,720 --> 03:41:00,000
AND I'M SO GLAD TO HEAR THAT

5460
03:41:00,000 --> 03:41:00,760
BEING EMPHASIZED, REALLY GETS TO

5461
03:41:00,760 --> 03:41:04,960
THE HEART OF WHAT HEALING IS ALL

5462
03:41:04,960 --> 03:41:05,920
ABOUT.

5463
03:41:05,920 --> 03:41:10,080
THANK YOU SO MUCH FOR SERVING AS

5464
03:41:10,080 --> 03:41:10,640
DIRECTOR.

5465
03:41:10,640 --> 03:41:13,080
YOU'RE TRANSFORMING THE WHOLE OF

5466
03:41:13,080 --> 03:41:15,440
THE NCCIH, I KNOW I SPEAK ON

5467
03:41:15,440 --> 03:41:16,760
EVERYONE'S BEHALF BY SAYING HOW

5468
03:41:16,760 --> 03:41:17,760
GRATEFUL WE ARE.

5469
03:41:17,760 --> 03:41:18,520
THANK YOU.

5470
03:41:18,520 --> 03:41:22,280
>> WE'RE ALL ON THIS JOURNEY

5471
03:41:22,280 --> 03:41:22,680
TOGETHER.

5472
03:41:22,680 --> 03:41:23,840
IT'S BEEN GREAT.

5473
03:41:23,840 --> 03:41:25,160
ALL THE COUNCIL MEMBERS, I FEEL

5474
03:41:25,160 --> 03:41:27,320
LIKE YOU'RE ALL SUCH A GREAT

5475
03:41:27,320 --> 03:41:27,640
GROUP.

5476
03:41:27,640 --> 03:41:30,760
IT'S INTERESTING TO SEE HOW THE

5477
03:41:30,760 --> 03:41:33,920
GROUP EVOLVES BUT STILL STAYS

5478
03:41:33,920 --> 03:41:34,280
ONE.

5479
03:41:34,280 --> 03:41:40,160
IT'S  GREAT. 

5480
03:41:40,160 --> 03:41:41,160
THANK YOU FOR YOUR

5481
03:41:41,160 --> 03:41:44,640
CONTRIBUTIONS, ALL OF YOU.

5482
03:41:44,640 --> 03:41:47,360
WE'LL MISS YOU.

5483
03:41:47,360 --> 03:41:48,280
 

5484
03:41:48,280 --> 03:41:50,560
>> THANK YOU, EVERYONE.

5485
03:41:50,560 --> 03:41:53,840
WE'RE NOW GOING TO GO CLOSE TO

5486
03:41:53,840 --> 03:41:55,760
THE LAST THING, CONCEPT

5487
03:41:55,760 --> 03:41:57,760
CLEARANCE, PRESENTED BY DR.

5488
03:41:57,760 --> 03:42:00,520
CRAIG HOPP, DEPUTY DIRECTOR OF

5489
03:42:00,520 --> 03:42:06,080
THE DIVISION OF EXTRAMURAL 

5490
03:42:06,080 --> 03:42:06,320
RESEARCH.

5491
03:42:06,320 --> 03:42:09,160
CRAIG? 

5492
03:42:09,160 --> 03:42:10,720
>> THERE WE GO.

5493
03:42:10,720 --> 03:42:17,720
I'LL TURN ON MY CAMERA.

5494
03:42:17,720 --> 03:42:18,800
 

5495
03:42:18,800 --> 03:42:21,640
>> PRESENTATION VIEW.

5496
03:42:21,640 --> 03:42:21,960
>> YES.

5497
03:42:21,960 --> 03:42:23,560
LET'S SEE IF I CAN FIGURE OUT

5498
03:42:23,560 --> 03:42:26,720
HOW TO DO THAT.

5499
03:42:26,720 --> 03:42:27,480
HOW ABOUT NOW?

5500
03:42:27,480 --> 03:42:29,320
>> YES.

5501
03:42:29,320 --> 03:42:29,720
>> WONDERFUL.

5502
03:42:29,720 --> 03:42:31,160
SO, GOOD AFTERNOON, EVERYONE.

5503
03:42:31,160 --> 03:42:34,120
I'M HAPPY TO PRESENT TO YOU

5504
03:42:34,120 --> 03:42:36,960
TODAY A CONCEPT FOR NCCIH

5505
03:42:36,960 --> 03:42:37,920
HIGH-PRIORITY PAIN RESEARCH,

5506
03:42:37,920 --> 03:42:38,960
THERE'S THAT WORD AGAIN.

5507
03:42:38,960 --> 03:42:42,240
YOU HEARD A LOT ALL DAY LONG

5508
03:42:42,240 --> 03:42:43,960
WITH THE ONGOING ACTIVITIES

5509
03:42:43,960 --> 03:42:49,120
ACROSS A VARIETY OF SPECTRUM OF

5510
03:42:49,120 --> 03:42:51,160
PAIN-RELATED ACTIVITIES.

5511
03:42:51,160 --> 03:42:55,560
THIS CONCEPT WOULD CONTINUE, AS

5512
03:42:55,560 --> 03:42:58,760
EMMELINE INDICATED, EXTEND THE

5513
03:42:58,760 --> 03:43:01,280
ARC OF ACTIVITIES.

5514
03:43:01,280 --> 03:43:05,200
I'LL REMIND FOLKS A CONCEPT IS

5515
03:43:05,200 --> 03:43:08,040
AN INTENTIONALLY BROAD BASKET OF

5516
03:43:08,040 --> 03:43:09,960
INTEREST AREAS THAT NCCIH HAS

5517
03:43:09,960 --> 03:43:12,920
THAT ALLOWS US FLEXIBILITY TO

5518
03:43:12,920 --> 03:43:14,440
HAVE POTENTIALLY MULTIPLE

5519
03:43:14,440 --> 03:43:14,880
FUNDING OPPORTUNITY

5520
03:43:14,880 --> 03:43:16,200
ANNOUNCEMENTS THAT WOULD BE

5521
03:43:16,200 --> 03:43:18,360
COVERED UNDER SUCH A CONCEPT.

5522
03:43:18,360 --> 03:43:19,880
HOWEVER, BY NIH POLICY, WE DO

5523
03:43:19,880 --> 03:43:22,520
NOT DISCUSS ANY OF THE DETAILS

5524
03:43:22,520 --> 03:43:24,840
OF ANY INITIATIVE OR FUNDING

5525
03:43:24,840 --> 03:43:27,880
OPPORTUNITY THAT MIGHT EMERGE

5526
03:43:27,880 --> 03:43:30,960
FROM THIS, THIS ONE, PRESERVES

5527
03:43:30,960 --> 03:43:32,520
FLEXIBILITY TO IMPLEMENT CONCEPT

5528
03:43:32,520 --> 03:43:36,200
AND, TWO, FOR YOUR BENEFIT, YOU

5529
03:43:36,200 --> 03:43:37,960
CAN ALL AS COUNCIL MEMBERS

5530
03:43:37,960 --> 03:43:39,840
SUBMIT APPLICATIONS TO THESE

5531
03:43:39,840 --> 03:43:40,200
THINGS.

5532
03:43:40,200 --> 03:43:44,560
SO, WE'VE TALKED ABOUT THIS ALL

5533
03:43:44,560 --> 03:43:44,720
DAY.

5534
03:43:44,720 --> 03:43:46,840
WE'RE IN THE MIDST, IN THE

5535
03:43:46,840 --> 03:43:48,800
THROES OF A PUBLIC HEALTH

5536
03:43:48,800 --> 03:43:50,880
EMERGENCY RELATED TO THE OPIOID

5537
03:43:50,880 --> 03:43:53,320
MISUSE AND ADDICTION CRISIS,

5538
03:43:53,320 --> 03:43:57,560
FIRST DECLARED IN OCTOBER OF 

5539
03:43:57,560 --> 03:43:58,960
2017, RENEWED EVERY THREE

5540
03:43:58,960 --> 03:44:00,480
MONTHS, REMAINS ACTIVE.

5541
03:44:00,480 --> 03:44:04,360
WE STILL HAVE ONGOING PAIN

5542
03:44:04,360 --> 03:44:04,640
EMERGENCY.

5543
03:44:04,640 --> 03:44:05,520
SUBSEQUENT, CONGRESS

5544
03:44:05,520 --> 03:44:06,720
APPROPRIATED THE NIH WITH A HUGE

5545
03:44:06,720 --> 03:44:08,240
AMOUNT OF MONEY, HUNDREDS OF

5546
03:44:08,240 --> 03:44:11,160
MILLIONS OF DOLLARS, WHICH AS

5547
03:44:11,160 --> 03:44:15,240
YOU ALL KNOW NOW NIH PACKAGED

5548
03:44:15,240 --> 03:44:17,280
INTO THE HEAL INITIATIVE.

5549
03:44:17,280 --> 03:44:24,640
IT HAS TWO PRIMARY THRUSTS. 

5550
03:44:24,640 --> 03:44:28,560
ONE IS IMPROVEMENTS IN OPIOID

5551
03:44:28,560 --> 03:44:35,960
MISMUX OF USE --  MISUSE AND

5552
03:44:35,960 --> 03:44:37,440
ADDICTION AND IMPROVEMENT IN THE

5553
03:44:37,440 --> 03:44:37,640
PAIN.

5554
03:44:37,640 --> 03:44:39,720
YOU WOULD THINK AFTER ALL THE

5555
03:44:39,720 --> 03:44:41,560
INVESTMENT WE'VE MADE A LARGE

5556
03:44:41,560 --> 03:44:45,120
AMOUNT OF PROGRESS IN THE OPIOID

5557
03:44:45,120 --> 03:44:45,320
CRISIS.

5558
03:44:45,320 --> 03:44:47,320
THAT'S NOT THE CASE.

5559
03:44:47,320 --> 03:44:49,720
CDC REPORTED RECENTLY IN 12

5560
03:44:49,720 --> 03:44:51,760
MONTHS ENDING APRIL OF 2021

5561
03:44:51,760 --> 03:45:01,960
THERE WERE OVER 100,000 DRUG

5562
03:45:01,960 --> 03:45:04,960
OVERDEATHS IN THE U.S. ALONE.

5563
03:45:04,960 --> 03:45:07,600
THERE'S RUMOR THAT WE MIGHT HAVE

5564
03:45:07,600 --> 03:45:10,120
A LOT MORE FUNDS TO ADDRESS

5565
03:45:10,120 --> 03:45:10,920
THIS.

5566
03:45:10,920 --> 03:45:13,760
SPECIFICALLY TARGETED FOR PAIN

5567
03:45:13,760 --> 03:45:15,560
RESEARCH, IN ADDITION TO AND

5568
03:45:15,560 --> 03:45:17,240
SEPARATE FROM THE HEAL

5569
03:45:17,240 --> 03:45:19,240
INITIATIVE, ALSO GOING TO BE

5570
03:45:19,240 --> 03:45:20,200
GETTING MORE MONEY.

5571
03:45:20,200 --> 03:45:23,280
SO WITH THAT IN MIND NCCIH IS

5572
03:45:23,280 --> 03:45:24,560
INTERESTED IN DEVELOPING

5573
03:45:24,560 --> 03:45:27,760
INITIATIVE THAT WOULD DIRECTLY 

5574
03:45:27,760 --> 03:45:30,080
ADDRESS THIS OPIOID CRISIS

5575
03:45:30,080 --> 03:45:32,560
THROUGH THE IMPROVED MANAGEMENT

5576
03:45:32,560 --> 03:45:33,760
OF NON-PHARMACOLOGIC PANDEMIC

5577
03:45:33,760 --> 03:45:34,760
NON-ADDICTIVE PAIN APPROACHES.

5578
03:45:34,760 --> 03:45:38,160
AND THE GOALS OF THE CONCEPT ARE

5579
03:45:38,160 --> 03:45:38,920
MULTI-FOLD.

5580
03:45:38,920 --> 03:45:40,680
ONE, WE WANT TO ACCELERATE AND

5581
03:45:40,680 --> 03:45:42,640
CONTINUE TO INVEST IN PAIN

5582
03:45:42,640 --> 03:45:45,720
RESEARCH AND BY FOCUSING ON PAIN

5583
03:45:45,720 --> 03:45:46,760
THERE BY ADDRESSING THE

5584
03:45:46,760 --> 03:45:48,760
UNDERLYING CAUSE OF THE OPIOID

5585
03:45:48,760 --> 03:45:50,320
MISUSE CRISIS.

5586
03:45:50,320 --> 03:45:53,760
THIS WILL ALLOW US BY

5587
03:45:53,760 --> 03:45:55,160
IMPLEMENTATION TO EXTEND OUR

5588
03:45:55,160 --> 03:45:57,600
EFFORTS TO FY 23 AND BEYOND,

5589
03:45:57,600 --> 03:45:58,960
WHILE ALSO FILLING GAPS IN

5590
03:45:58,960 --> 03:46:01,440
CURRENT INITIATIVES THAT WE HAVE

5591
03:46:01,440 --> 03:46:02,400
CURRENTLY ONGOING.

5592
03:46:02,400 --> 03:46:03,560
AND THE TOPICS YOU'RE GOING TO

5593
03:46:03,560 --> 03:46:04,840
SEE OVER THE NEXT TWO SLIDES

5594
03:46:04,840 --> 03:46:06,360
SHOULD BE VERY FAMILIAR TO YOU

5595
03:46:06,360 --> 03:46:09,400
BECAUSE THEY HAVE BEEN MENTIONED

5596
03:46:09,400 --> 03:46:11,480
IN OTHER PLACES THROUGHOUT THE

5597
03:46:11,480 --> 03:46:16,160
DAY, THE POINT IS THAT WE'LL BE,

5598
03:46:16,160 --> 03:46:17,280
AGAIN, UTILIZING THESE THINGS TO

5599
03:46:17,280 --> 03:46:19,760
FILL IN GAPS IN EXISTING

5600
03:46:19,760 --> 03:46:22,400
PORTFOLIO AS WELL AS TRYING TO

5601
03:46:22,400 --> 03:46:23,800
ADDRESS OPIOID MISUSE CRISIS

5602
03:46:23,800 --> 03:46:25,680
THAT WE HAVE STILL ONGOING.

5603
03:46:25,680 --> 03:46:27,120
SO, AGAIN, THESE TOPICS ARE

5604
03:46:27,120 --> 03:46:29,520
THINGS YOU'VE SEEN FOCUSING ON

5605
03:46:29,520 --> 03:46:34,440
SICKLE CELL DISEASE, MYOFASCIAL

5606
03:46:34,440 --> 03:46:35,760
PAIN, FORCE BASED MANIPULATION,

5607
03:46:35,760 --> 03:46:39,040
NATURAL PRODUCTS BUT DO GO IN

5608
03:46:39,040 --> 03:46:40,320
DIFFERENT DIRECTIONS, PUBLISHED

5609
03:46:40,320 --> 03:46:42,080
INITIATIVES ARE CURRENTLY

5610
03:46:42,080 --> 03:46:44,160
INVOLVED N FOR EXAMPLE

5611
03:46:44,160 --> 03:46:46,360
MYOFASCIAL PAIN HEAL INITIATIVE

5612
03:46:46,360 --> 03:46:47,600
IS FOCUSED ON CLINICAL RESEARCH.

5613
03:46:47,600 --> 03:46:49,760
WITHIN THIS CONCEPT WE'RE

5614
03:46:49,760 --> 03:46:51,960
INTERESTED IN BASIC AND

5615
03:46:51,960 --> 03:46:52,800
MECHANISTIC RESEARCH.

5616
03:46:52,800 --> 03:46:54,120
SIMILARLY WE'RE INTERESTED IN

5617
03:46:54,120 --> 03:47:00,640
MUSIC THERAPIES FOR PAIN

5618
03:47:00,640 --> 03:47:01,480
MANAGEMENT, MULTI-COMPONENT,

5619
03:47:01,480 --> 03:47:05,280
AND mHEALTH TRIALS USING 

5620
03:47:05,280 --> 03:47:06,560
COMPLEMENTARY AND INTEGRATIVE

5621
03:47:06,560 --> 03:47:07,320
INTERVENTIONS.

5622
03:47:07,320 --> 03:47:10,120
I WILL CONCLUDE THE CONCEPT

5623
03:47:10,120 --> 03:47:10,760
CLEARANCE PRESENTATION AND LOOK

5624
03:47:10,760 --> 03:47:16,160
FORWARD TO QUESTIONS OR COMMENTS

5625
03:47:16,160 --> 03:47:17,760
THAT COUNCIL MIGHT HAVE.

5626
03:47:17,760 --> 03:47:19,600
>> QUESTIONS FOR DR. HOPP

5627
03:47:19,600 --> 03:47:28,720
REGARDING THIS CONCEPT, FROM

5628
03:47:28,720 --> 03:47:41,560
COUNCIL? 

5629
03:47:41,560 --> 03:47:42,560
>> SILENCE IS GOLDEN.

5630
03:47:42,560 --> 03:47:44,120
>> THAT'S FINE.

5631
03:47:44,120 --> 03:47:47,880
I'LL ASK FOR A MOTION FOR

5632
03:47:47,880 --> 03:47:49,720
APPROVAL OF THIS CONCEPT.

5633
03:47:49,720 --> 03:47:52,200
>> SO MOVED.

5634
03:47:52,200 --> 03:47:52,560
>> A SECOND?

5635
03:47:52,560 --> 03:47:52,840
>>  SECOND.

5636
03:47:52,840 --> 03:47:54,400
>> ALL RIGHT.

5637
03:47:54,400 --> 03:47:57,840
IS THERE ANY DISCUSSION, FURTHER

5638
03:47:57,840 --> 03:47:58,800
DISCUSSION, ANY DISCUSSION MORE

5639
03:47:58,800 --> 03:48:02,760
THAN WHAT'S ALREADY BEEN DONE 

5640
03:48:02,760 --> 03:48:03,960
FOR THIS CONCEPT?

5641
03:48:03,960 --> 03:48:05,480
HEARING NONE, WE'LL GO AHEAD FOR

5642
03:48:05,480 --> 03:48:06,480
A VOTE.

5643
03:48:06,480 --> 03:48:08,560
FOR THOSE COUNCIL MEMBERS WHO

5644
03:48:08,560 --> 03:48:11,640
ARE ELIGIBLE TO VOTE, YOU'LL

5645
03:48:11,640 --> 03:48:15,360
HAVE A POLL APPEARING ON YOUR

5646
03:48:15,360 --> 03:48:15,600
SCREEN.

5647
03:48:15,600 --> 03:48:18,440
AND IF YOU'RE ASKING A -- A VOTE

5648
03:48:18,440 --> 03:48:20,760
FOR YES IS APPROVING, NO IS

5649
03:48:20,760 --> 03:48:22,240
OPPOSITE, YOU'RE NOT APPROVING, 

5650
03:48:22,240 --> 03:48:26,400
OR YOU MAY ABSTAIN. 

5651
03:48:26,400 --> 03:48:29,360
I'M NOW SEEING 18 VOTES.

5652
03:48:29,360 --> 03:48:31,000
IT'S UNANIMOUS, CONCEPT HAS BEEN

5653
03:48:31,000 --> 03:48:32,240
APPROVED BY COUNCIL.

5654
03:48:32,240 --> 03:48:34,800
THANK YOU VERY MUCH.

5655
03:48:34,800 --> 03:48:38,760
THANK YOU, DR. HOPP.

5656
03:48:38,760 --> 03:48:39,280
>> THANK YOU!

5657
03:48:39,280 --> 03:48:41,960
>> SO THE LAST MATTER ON THE

5658
03:48:41,960 --> 03:48:46,560
AGENDA, I WANT TO REMIND THE

5659
03:48:46,560 --> 03:48:48,360
PUBLIC THAT IF THERE ARE --

5660
03:48:48,360 --> 03:48:49,600
AGAIN, BECAUSE THIS MEETING IS

5661
03:48:49,600 --> 03:48:50,960
VIRTUAL THERE IS NOT AN

5662
03:48:50,960 --> 03:48:54,080
OPPORTUNITY FOR MEMBERS OF THE

5663
03:48:54,080 --> 03:48:55,160
PUBLIC TO PROVIDE IN-PERSON

5664
03:48:55,160 --> 03:48:55,520
COMMENTS.

5665
03:48:55,520 --> 03:48:57,160
SO MEMBERS OF THE PUBLIC, IF

5666
03:48:57,160 --> 03:48:58,920
THEY WISH TO MAKE COMMENTS THAT

5667
03:48:58,920 --> 03:49:00,640
WOULD BE HEARD MY COUNCIL, YOU

5668
03:49:00,640 --> 03:49:01,840
SHOULD SEND THEM IN WRITING.

5669
03:49:01,840 --> 03:49:04,040
YOU CAN SEND THEM TO ME, MY NAME

5670
03:49:04,040 --> 03:49:07,760
SAND ADDRESS -- AND ADDRESS ARE

5671
03:49:07,760 --> 03:49:09,880
ON THE AGENDA AND FEDERAL

5672
03:49:09,880 --> 03:49:10,160
REGISTER.

5673
03:49:10,160 --> 03:49:12,720
YOU HAVE WITHIN 15 DAYS OF THIS

5674
03:49:12,720 --> 03:49:14,680
MEETING TO SUBMIT WRITTEN

5675
03:49:14,680 --> 03:49:17,120
COMMENTS, THEY SHOULD BE LESS

5676
03:49:17,120 --> 03:49:19,320
THAN 700 WORDS IN LENGTH, WHICH

5677
03:49:19,320 --> 03:49:25,560
WOULD BE THE EQUIVALENT OF A

5678
03:49:25,560 --> 03:49:26,840
FIVE-MINUTE VERBAL PRESENTATION.

5679
03:49:26,840 --> 03:49:29,800
AND THOSE COMMENTS WILL THEN BE

5680
03:49:29,800 --> 03:49:33,240
SHARED DIRECTLY WITH COUNCIL 

5681
03:49:33,240 --> 03:49:34,760
MEMBERS VIA INTERNAL PROCESSES.

5682
03:49:34,760 --> 03:49:36,520
AND WITH THAT, I THINK WE'RE

5683
03:49:36,520 --> 03:49:40,200
COMING TO A CONCLUSION.

5684
03:49:40,200 --> 03:49:41,400
DR. LANGEVIN, YOUR FINAL REMARKS

5685
03:49:41,400 --> 03:49:43,640
FOR COUNCIL AND THE PUBLIC?

5686
03:49:43,640 --> 03:49:44,920
>>  WELL, THANK YOU VERY MUCH.

5687
03:49:44,920 --> 03:49:47,760
THIS HAS BEEN A VERY INTERESTING

5688
03:49:47,760 --> 03:49:48,160
MEETING.

5689
03:49:48,160 --> 03:49:50,600
I REALLY WANT TO THANK YOU ALL

5690
03:49:50,600 --> 03:49:54,000
FOR YOUR INPUT AND THOUGHTFUL

5691
03:49:54,000 --> 03:49:55,080
DISCUSSION ALSO, QUESTIONS,

5692
03:49:55,080 --> 03:49:57,360
INTERESTS. 

5693
03:49:57,360 --> 03:49:59,000
AS YOU CAN SEE, THIS HAS BEEN A

5694
03:49:59,000 --> 03:50:02,720
YEAR LIKE NO OTHER, AND I WANT

5695
03:50:02,720 --> 03:50:06,200
TO REALLY SAY A FEW WORDS ABOUT

5696
03:50:06,200 --> 03:50:11,880
THE FACT THAT WE RECOGNIZE, VERY

5697
03:50:11,880 --> 03:50:15,680
MUCH SO, HOW IN SOME WAYS

5698
03:50:15,680 --> 03:50:17,120
OVERWHELMING AND A LITTLE SCARY

5699
03:50:17,120 --> 03:50:18,440
IT IS, ALL THIS INFORMATION

5700
03:50:18,440 --> 03:50:21,160
WE'VE GIVEN YOU ABOUT ALL THESE

5701
03:50:21,160 --> 03:50:21,960
FUNDING OPPORTUNITIES.

5702
03:50:21,960 --> 03:50:24,240
WE REALIZE THIS IS A LOT.

5703
03:50:24,240 --> 03:50:28,280
WE REALIZE EVERYBODY IS GETTING

5704
03:50:28,280 --> 03:50:30,480
SORT OF TIRED AND I THINK THAT

5705
03:50:30,480 --> 03:50:36,040
THE IMPORTANT THING TO REMEMBER

5706
03:50:36,040 --> 03:50:39,560
IS THAT IF INDEED THERE IS

5707
03:50:39,560 --> 03:50:41,400
ADDITIONAL FUNDS FOR PAIN, THIS

5708
03:50:41,400 --> 03:50:47,880
WOULD BE AN OPPORTUNITY FOR

5709
03:50:47,880 --> 03:50:51,160
REALLY -- I DON'T WANT TO SAY

5710
03:50:51,160 --> 03:50:52,880
THE WORD JUMP START BECAUSE THE

5711
03:50:52,880 --> 03:50:58,480
HEAL INITIATIVE HAS  ALREADY

5712
03:50:58,480 --> 03:51:00,640
DONE THAT, AS CRAIG MENTIONED.

5713
03:51:00,640 --> 03:51:01,920
THE HEAL INITIATIVE WAS TO

5714
03:51:01,920 --> 03:51:03,720
ADDRESS THE PAIN CRISIS.

5715
03:51:03,720 --> 03:51:07,560
BUT WHAT WAS REALLY MISSING WAS

5716
03:51:07,560 --> 03:51:08,760
OTHER, YOU KNOW, OPPORTUNITIES

5717
03:51:08,760 --> 03:51:10,400
THAT WERE DISTRIBUTED THROUGH

5718
03:51:10,400 --> 03:51:12,320
THE INSTITUTES, AND I THINK THIS

5719
03:51:12,320 --> 03:51:15,080
IS WHAT WAS RECOGNIZED IS THAT

5720
03:51:15,080 --> 03:51:16,800
THE FOCUS OF "HEAL" IS VERY

5721
03:51:16,800 --> 03:51:18,560
FOCUSED AND THERE ARE SOME OTHER

5722
03:51:18,560 --> 03:51:25,160
TYPES OF RESEARCH THAT CANNOT BE

5723
03:51:25,160 --> 03:51:27,320
FUNDED WITHIN THE HEAL

5724
03:51:27,320 --> 03:51:28,200
INITIATIVE, HAVING MORE

5725
03:51:28,200 --> 03:51:30,560
DISCRETIONARY FUNDING IS HELPFUL

5726
03:51:30,560 --> 03:51:31,360
ESPECIALLY IF INSTITUTES CAN

5727
03:51:31,360 --> 03:51:32,240
COMBINE TOGETHER LIKE WE'RE

5728
03:51:32,240 --> 03:51:34,760
TRYING TO DO WITH RE-JOIN,

5729
03:51:34,760 --> 03:51:37,280
WITHIN "HEAL" OR EVEN OUTSIDE OF

5730
03:51:37,280 --> 03:51:37,440
IT.

5731
03:51:37,440 --> 03:51:39,480
SO, IT'S GOOD NEWS AND BAD NEWS,

5732
03:51:39,480 --> 03:51:40,000
YOU KNOW.

5733
03:51:40,000 --> 03:51:42,880
GOOD NEWS THAT THERE MAY BE SOME

5734
03:51:42,880 --> 03:51:43,640
INCREASED ADDITIONAL FUNDS.

5735
03:51:43,640 --> 03:51:44,600
WE DON'T KNOW.

5736
03:51:44,600 --> 03:51:47,440
THE BAD NEWS IS THAT THE

5737
03:51:47,440 --> 03:51:50,400
TIMELINES ARE TIGHT.

5738
03:51:50,400 --> 03:51:53,480
I'M GOING TO SAY WE ALL DO WHAT

5739
03:51:53,480 --> 03:51:55,120
WE CAN.

5740
03:51:55,120 --> 03:51:57,760
IT'S NOT OUR FAULT DEADLINES ARE

5741
03:51:57,760 --> 03:51:57,960
CRAZY.

5742
03:51:57,960 --> 03:51:59,800
WE ARE SUFFERING FROM IT AS

5743
03:51:59,800 --> 03:52:00,800
WELL, YOU KNOW, IN TERMS OF

5744
03:52:00,800 --> 03:52:02,880
STRAIN ON OUR STAFF TO TRY TO

5745
03:52:02,880 --> 03:52:07,240
TURN THIS AROUND AS YOU CAN SEE

5746
03:52:07,240 --> 03:52:09,520
FROM EMMELINE DESCRIBING FUNDING

5747
03:52:09,520 --> 03:52:10,720
OPPORTUNITIES, ENORMOUS AMOUNT

5748
03:52:10,720 --> 03:52:12,160
OF WORK TO PUT THAT TOGETHER.

5749
03:52:12,160 --> 03:52:13,440
WE'RE ALL IN THIS TOGETHER.

5750
03:52:13,440 --> 03:52:17,800
LET'S JUST HOPE FOR THE BEST AND

5751
03:52:17,800 --> 03:52:19,960
IF THE FUNDS DON'T MATERIALIZE

5752
03:52:19,960 --> 03:52:25,760
THEN WE'LL HAVE LESS TO DO.

5753
03:52:25,760 --> 03:52:27,400
BUT ONE WAY OR ANOTHER WE'LL

5754
03:52:27,400 --> 03:52:28,600
KEEP, YOU KNOW, DOING EVERYTHING

5755
03:52:28,600 --> 03:52:31,280
THE BEST THAT WE CAN WITH THE

5756
03:52:31,280 --> 03:52:34,840
RESOURCES THAT WE HAVE.

5757
03:52:34,840 --> 03:52:37,160
SO, THANK YOU AGAIN, AND GOOD

5758
03:52:37,160 --> 03:52:38,320
LUCK GETTING OUT OF THIS

5759
03:52:38,320 --> 03:52:38,760
PANDEMIC.

5760
03:52:38,760 --> 03:52:43,280
I HOPE THE NEXT TIME WE MEET, IT

5761
03:52:43,280 --> 03:52:45,320
MAY NOT BE IN PERSON BUT I HOPE

5762
03:52:45,320 --> 03:52:48,880
IT WON'T BE IN COVID.

5763
03:52:48,880 --> 03:52:50,440
HAVE A GOOD EVENING, EVERYONE.

5764
03:52:50,440 --> 03:52:53,160
HAVE A GOOD WEEKEND.

5765
03:52:53,160 --> 03:52:54,560
>> THANK YOU, DR. LANGEVIN.

5766
03:52:54,560 --> 03:52:55,960
WITH THAT WE'LL CLOSE THIS

5767
03:52:55,960 --> 03:52:57,160
MEETING OF COUNCIL.

5768
03:52:57,160 --> 03:52:58,360
THANK YOU, COUNCIL, FOR YOUR

5769
03:52:58,360 --> 03:53:01,760
TIME AND EFFORTS. 

5770
03:53:01,760 --> 03:53:03,160
IT'S BEEN A DELIGHT AND HONOR TO

5771
03:53:03,160 --> 03:53:04,400
BE WITH YOU TODAY.

5772
03:53:04,400 --> 03:53:04,760
>> BYE.

5773
03:53:04,760 --> 00:00:00,000
>> THANK YOU SO MUCH.