1 00:00:06,960 --> 00:00:11,000 WELCOME TO THE 60th MEETING OF 2 00:00:11,000 --> 00:00:12,560 THE NATIONAL ADVISORY COUNCIL 3 00:00:12,560 --> 00:00:15,720 FOR BIOMEDICAL IMAGE AND 4 00:00:15,720 --> 00:00:16,680 BIOENGINEERING. 5 00:00:16,680 --> 00:00:19,240 I'M DAVE GEORGE, NIBIB ASSOCIATE 6 00:00:19,240 --> 00:00:20,440 DIRECTOR, ASSOCIATE SECRETARY OF 7 00:00:20,440 --> 00:00:21,280 THIS COMMITTEE. 8 00:00:21,280 --> 00:00:23,720 THIS COUNCIL MEETING IS OPEN TO 9 00:00:23,720 --> 00:00:25,320 THE PUBLIC, EXCEPT FOR THE 10 00:00:25,320 --> 00:00:26,520 REVIEW OF PENDING GRANT 11 00:00:26,520 --> 00:00:28,560 APPLICATIONS WHICH WILL TAKE 12 00:00:28,560 --> 00:00:29,680 PLACE LATER THIS AFTERNOON. 13 00:00:29,680 --> 00:00:31,880 THE OPEN SESSION OF THE COUNCIL 14 00:00:31,880 --> 00:00:34,840 MEETING IS BEING LIVE BROADCAST 15 00:00:34,840 --> 00:00:36,360 ON THE NIH VIDEOCAST NETWORK, 16 00:00:36,360 --> 00:00:38,960 AND RECORDED FOR NIH ARCHIVES. 17 00:00:38,960 --> 00:00:41,680 THE COMMITTEE AND PRESENTERS ARE 18 00:00:41,680 --> 00:00:42,880 PARTICIPATING VIA VIDEO 19 00:00:42,880 --> 00:00:43,200 CONFERENCE. 20 00:00:43,200 --> 00:00:46,520 I'D LIKE TO WELCOME OUR COUNCIL 21 00:00:46,520 --> 00:00:47,920 MEMBERS, EX OFFICIO, SPECIAL 22 00:00:47,920 --> 00:00:48,400 GUESTS. 23 00:00:48,400 --> 00:00:51,840 THANK YOU TO ALL THOSE WATCHING 24 00:00:51,840 --> 00:00:52,680 ON VIDEOCAST. 25 00:00:52,680 --> 00:00:54,200 THOSE OF YOU MEMBERS OF THE 26 00:00:54,200 --> 00:00:57,160 PUBLIC WHO WISH TO EXPRESS VIEWS 27 00:00:57,160 --> 00:01:00,800 REGARDING ANY ITEMS DISCUSSED 28 00:01:00,800 --> 00:01:05,480 DURING THIS MEETING MAY DO SO IN 29 00:01:05,480 --> 00:01:10,640 WRITING WITHIN TEN DAYS, INFO@ 30 00:01:10,640 --> 00:01:18,640 NIBIB.NIH.GOV. 31 00:01:18,640 --> 00:01:23,040 THAT'S INFO@NIBIB.NIH.GOV. 32 00:01:23,040 --> 00:01:24,480 AND PLEASE PUT NIBIB COUNCIL IN 33 00:01:24,480 --> 00:01:27,160 THE SUBJECT LINE OF THE E-MAIL. 34 00:01:27,160 --> 00:01:32,240 FOR THOSE WHO ARE IN THE VIDEO 35 00:01:32,240 --> 00:01:35,000 CONFERENCE, YOU'RE FAMILIAR WITH 36 00:01:35,000 --> 00:01:37,480 THIS BY NOW BUT REMINDERS, MUTE 37 00:01:37,480 --> 00:01:39,080 YOURSELF WHEN NOT SPEAKING, FOR 38 00:01:39,080 --> 00:01:41,280 COLLEAGUES AND GUESTS WHO ARE 39 00:01:41,280 --> 00:01:42,480 PRESENTING A REMINDER TO PRESENT 40 00:01:42,480 --> 00:01:47,160 FROM A FILE LOCATED ON YOUR 41 00:01:47,160 --> 00:01:48,680 COMPUTER'S HARD DRIVE RATHER 42 00:01:48,680 --> 00:01:50,840 THAN NETWORK DRIVE AND BE LOGGED 43 00:01:50,840 --> 00:01:52,960 OR VPN AND SHUT OFF UNNEEDED 44 00:01:52,960 --> 00:01:56,440 SOFTWARE NOTIFICATIONS IF YOU 45 00:01:56,440 --> 00:01:56,880 CAN. 46 00:01:56,880 --> 00:01:59,520 THE CHAT BOX IS ENABLED FOR YOU 47 00:01:59,520 --> 00:02:00,880 TO CONTACT OUR HOST 48 00:02:00,880 --> 00:02:03,200 OUR I.T. COLLEAGUE, WHO IS 49 00:02:03,200 --> 00:02:05,400 MANAGING THE VIDEO CONFERENCE 50 00:02:05,400 --> 00:02:06,920 TODAY. 51 00:02:06,920 --> 00:02:08,880 AS WELL IN ADDITION, IF YOU WANT 52 00:02:08,880 --> 00:02:12,080 TO CONTACT HIM VIA E-MAIL FOR 53 00:02:12,080 --> 00:02:18,880 ANY TECHNICAL PROBLEMS, HIS 54 00:02:18,880 --> 00:02:26,520 E-MAIL ADDRESS IS 55 00:02:26,520 --> 00:02:26,920 RYAN.DAVA@NIH.GOV. 56 00:02:26,920 --> 00:02:28,160 I'D LIKE TO NOTE FOR THE RECORD 57 00:02:28,160 --> 00:02:31,120 WE HAVE A QUORUM FOR TODAY'S 58 00:02:31,120 --> 00:02:31,480 MEETING. 59 00:02:31,480 --> 00:02:34,160 I'D LIKE TO THANK NIBIB 60 00:02:34,160 --> 00:02:36,120 COMMITTEE MANAGING OFFICER PAM 61 00:02:36,120 --> 00:02:37,880 GLICKMAN AND COMMITTEE MANAGING 62 00:02:37,880 --> 00:02:39,080 SPECIALIST ALICIA HOPKINS FOR 63 00:02:39,080 --> 00:02:41,280 THEIR HELP IN GETTING THE 64 00:02:41,280 --> 00:02:43,680 MEETING ORGANIZED AND HELPING 65 00:02:43,680 --> 00:02:46,200 GET THE INSTITUTE TO THIS THRICE 66 00:02:46,200 --> 00:02:48,240 ANNUAL MEETING AND AGAIN TO RYAN 67 00:02:48,240 --> 00:02:50,680 AND OUR NIBIB I.T. COLLEAGUES, 68 00:02:50,680 --> 00:02:52,200 OUR NIH VIDEOCAST COLLEAGUES, 69 00:02:52,200 --> 00:02:54,360 AND OTHER STAFF MEMBERS WHO 70 00:02:54,360 --> 00:02:59,600 WORKED ON THE VIDEO 71 00:02:59,600 --> 00:03:00,160 ARRANGEMENTS. 72 00:03:00,160 --> 00:03:01,080 THE PROCEEDINGS ARE GOVERNED BY 73 00:03:01,080 --> 00:03:03,040 THE FEDERALLY ADVISORY COMMITTEE 74 00:03:03,040 --> 00:03:04,920 ACT, FACA, AND THE GOVERNMENT IN 75 00:03:04,920 --> 00:03:07,280 THE SUNSHINE ACT, SO THIS MEANS 76 00:03:07,280 --> 00:03:09,240 THE MEETING WAS ANNOUNCED TO THE 77 00:03:09,240 --> 00:03:10,880 PUBLIC IN THE FEDERAL REGISTER, 78 00:03:10,880 --> 00:03:12,280 AND CONSISTS OF OPEN PORTION 79 00:03:12,280 --> 00:03:13,680 THAT WE'RE IN NOW AND THEN A 80 00:03:13,680 --> 00:03:15,880 CLOSED PORTION THAT WILL BE 81 00:03:15,880 --> 00:03:18,480 LATER IN THE AFTERNOON, WE'LL 82 00:03:18,480 --> 00:03:19,480 TALK ABOUT INDIVIDUAL 83 00:03:19,480 --> 00:03:21,080 APPLICATIONS, WE ANTICIPATE 84 00:03:21,080 --> 00:03:23,320 ADJOURNING THE OPEN SESSION AT 85 00:03:23,320 --> 00:03:24,520 ABOUT 2:30. 86 00:03:24,520 --> 00:03:26,080 IN TERMS OF FUTURE COUNCIL 87 00:03:26,080 --> 00:03:28,880 DATES, THEY ARE LISTED AT THE 88 00:03:28,880 --> 00:03:31,000 BOTTOM OF THE AGENDA, COUNCIL 89 00:03:31,000 --> 00:03:31,920 MEMBERS IN THE ELECTRONIC 90 00:03:31,920 --> 00:03:32,680 COUNCIL BOOK. 91 00:03:32,680 --> 00:03:34,680 WE ASK IF YOU COULD DOUBLE CHECK 92 00:03:34,680 --> 00:03:38,480 THOSE FUTURE DATES, MAKE SURE WE 93 00:03:38,480 --> 00:03:39,280 DIDN'T ACCIDENTALLY SCHEDULE A 94 00:03:39,280 --> 00:03:41,360 MEETING ON TOP OF A CONFERENCE 95 00:03:41,360 --> 00:03:44,120 THAT MAY TAKE AWAY A NUMBER OF 96 00:03:44,120 --> 00:03:45,280 YOU AND CAUSE CONFLICTS. 97 00:03:45,280 --> 00:03:48,680 NEXT MEETING WILL BE JANUARY 25, 98 00:03:48,680 --> 00:03:49,120 2023. 99 00:03:49,120 --> 00:03:51,200 AND THE JANUARY MEETING WILL 100 00:03:51,200 --> 00:03:54,800 AGAIN BE HELD BY VIDEO 101 00:03:54,800 --> 00:03:55,080 CONFERENCE. 102 00:03:55,080 --> 00:03:56,440 I'D LIKE TO MOVE INTO THE 103 00:03:56,440 --> 00:03:59,200 CONSIDERATION OF THE MINUTES AND 104 00:03:59,200 --> 00:04:01,800 COUNCIL OPERATING PROCEDURES. 105 00:04:01,800 --> 00:04:06,600 AGAIN, WE POSTED THOSE TWO ITEMS 106 00:04:06,600 --> 00:04:07,680 INTO THE ELECTRONIC COUNCIL 107 00:04:07,680 --> 00:04:09,680 BOOK, IN REPRESENT OPERATION FOR 108 00:04:09,680 --> 00:04:12,760 BODYING, COUNCIL MEMBERS, UNMUTE 109 00:04:12,760 --> 00:04:14,320 YOURSELVES IN PREPARATION FOR 110 00:04:14,320 --> 00:04:15,280 CASTING A VOICE VOTE. 111 00:04:15,280 --> 00:04:19,080 ARE THERE ANY COMMENTS OR 112 00:04:19,080 --> 00:04:21,280 MODIFICATIONS YOU'D LIKE TO MAKE 113 00:04:21,280 --> 00:04:22,680 TO THE MINUTES? 114 00:04:22,680 --> 00:04:23,560 OKAY, HEARING NONE I'LL 115 00:04:23,560 --> 00:04:26,080 ENTERTAIN A MOTION TO APPROVE 116 00:04:26,080 --> 00:04:27,160 THE MINUTES. 117 00:04:27,160 --> 00:04:29,360 >> I MOVE. 118 00:04:29,360 --> 00:04:31,280 >> SO MOVED. 119 00:04:31,280 --> 00:04:31,960 >> SECOND? 120 00:04:31,960 --> 00:04:32,560 >> SECOND. 121 00:04:32,560 --> 00:04:34,480 >> ALL IN FAVOR, AYE. 122 00:04:34,480 --> 00:04:34,720 >> AYE. 123 00:04:34,720 --> 00:04:35,640 >> AYE. 124 00:04:35,640 --> 00:04:36,600 >> AYE. 125 00:04:36,600 --> 00:04:39,080 >> AYE. 126 00:04:39,080 --> 00:04:40,000 >> AYE. 127 00:04:40,000 --> 00:04:41,280 >> ALL OPPOSED, NAY. 128 00:04:41,280 --> 00:04:41,960 OKAY. 129 00:04:41,960 --> 00:04:43,000 THANK YOU VERY MUCH. 130 00:04:43,000 --> 00:04:51,040 NOW WE'LL MOVE TO THE COUNCIL 131 00:04:51,040 --> 00:04:51,640 OPERATING PROCEDURES. 132 00:04:51,640 --> 00:04:54,200 WE MADE A MINOR TWEAK TO BE 133 00:04:54,200 --> 00:04:55,440 CONSISTENT WITH NIH POLICY, MADE 134 00:04:55,440 --> 00:04:56,760 AVAILABLE A COUPLE WEEKS AGO. 135 00:04:56,760 --> 00:04:59,080 ARE THERE ANY COMMENTS OR 136 00:04:59,080 --> 00:05:03,200 MODIFICATIONS YOU'D LIKE TO MAKE 137 00:05:03,200 --> 00:05:04,520 TO OPERATING PROCEDURES? 138 00:05:04,520 --> 00:05:05,840 OKAY, AGAIN HEARING NONE I'LL 139 00:05:05,840 --> 00:05:08,600 ENTERTAIN A MOTION TO APPROVE 140 00:05:08,600 --> 00:05:10,880 THE OPERATING PROCEDURES. 141 00:05:10,880 --> 00:05:12,920 >> SO MOVED. 142 00:05:12,920 --> 00:05:15,080 >> MOVED. 143 00:05:15,080 --> 00:05:15,440 >> SECOND? 144 00:05:15,440 --> 00:05:15,880 >> SECOND. 145 00:05:15,880 --> 00:05:17,520 >> ALL IN FAVOR SAY AYE. 146 00:05:17,520 --> 00:05:19,880 >> AYE. 147 00:05:19,880 --> 00:05:21,760 >> AYE. 148 00:05:21,760 --> 00:05:24,520 >> AYE. 149 00:05:24,520 --> 00:05:24,960 >> AYE. 150 00:05:24,960 --> 00:05:27,040 >> ALL OPPOSED, NAY. 151 00:05:27,040 --> 00:05:27,280 OKAY. 152 00:05:27,280 --> 00:05:27,880 THOSE PASS. 153 00:05:27,880 --> 00:05:29,840 SO THANK YOU VERY MUCH. 154 00:05:29,840 --> 00:05:33,480 WITH THAT OPENING WE'LL MOVE 155 00:05:33,480 --> 00:05:38,280 INTO THE DIRECTOR'S REMARKS, 156 00:05:38,280 --> 00:05:41,360 GIVEN BY NIBIB DIRECTOR BRUCE 157 00:05:41,360 --> 00:05:45,680 TROMBERG AND DEPUTY DIRECTOR 158 00:05:45,680 --> 00:05:47,080 JILL HEEMSKERK. 159 00:05:47,080 --> 00:05:48,680 >> THANK YOU, DAVE, I'LL SHARE 160 00:05:48,680 --> 00:06:00,320 MY SCREEN. 161 00:06:00,320 --> 00:06:04,480 AND ACTUALLY BEFORE I DO THAT, 162 00:06:04,480 --> 00:06:06,600 WE HAVE A TRADITIONAL HOLLYWOOD 163 00:06:06,600 --> 00:06:07,680 SQUARES MOMENT. 164 00:06:07,680 --> 00:06:11,160 I KNOW THIS DOESN'T DO MUCH TO 165 00:06:11,160 --> 00:06:17,520 REALLY RECREATE THE LIVE FEELING 166 00:06:17,520 --> 00:06:22,680 BUT IF WE COULD TAKE A MOMENT TO 167 00:06:22,680 --> 00:06:23,680 FLASH ON AND SAY HI. 168 00:06:23,680 --> 00:06:25,960 MANY OF US HAVE BEEN FRIENDS AND 169 00:06:25,960 --> 00:06:26,760 COLLEAGUES, COLLABORATORS OVER 170 00:06:26,760 --> 00:06:28,160 SO MANY YEARS. 171 00:06:28,160 --> 00:06:30,440 AS YOU KNOW, IT'S FRUSTRATING TO 172 00:06:30,440 --> 00:06:33,720 BE IN THIS VERY STRUCTURED ZOOM 173 00:06:33,720 --> 00:06:35,400 ENVIRONMENT, WHICH DOESN'T ALLOW 174 00:06:35,400 --> 00:06:40,880 FOR ALL THE PARALLEL 175 00:06:40,880 --> 00:06:41,600 CONVERSATION, PROCESSING, 176 00:06:41,600 --> 00:06:42,400 BACKROOM DISCUSSIONS. 177 00:06:42,400 --> 00:06:43,880 WE'LL HAVE, YOU'LL SEE IN ONE OF 178 00:06:43,880 --> 00:06:46,000 MY SLIDES, WE'LL HAVE A LIVE 179 00:06:46,000 --> 00:06:48,280 COUNCIL MEETING, WE HOPE, IN 180 00:06:48,280 --> 00:06:48,680 MAY. 181 00:06:48,680 --> 00:06:50,280 AND I THINK THAT WILL BE AN 182 00:06:50,280 --> 00:06:53,440 ANNUAL EVENT, IF IT'S 183 00:06:53,440 --> 00:06:54,280 SUCCESSFUL, MAYBE MORE, BUT HARD 184 00:06:54,280 --> 00:06:57,520 TO LOOK TOO FAR INTO THE FUTURE. 185 00:06:57,520 --> 00:06:59,520 WE'RE JUST FOCUSING ON THAT 186 00:06:59,520 --> 00:07:00,720 FIRST BACK-TO-LIVE MEETING IN 187 00:07:00,720 --> 00:07:01,200 MAY. 188 00:07:01,200 --> 00:07:02,280 THANK YOU ALL FOR COMING. 189 00:07:02,280 --> 00:07:04,120 THANK YOU. 190 00:07:04,120 --> 00:07:08,400 WE HAVE A VERY PACKED PROGRAM AS 191 00:07:08,400 --> 00:07:08,840 USUAL. 192 00:07:08,840 --> 00:07:10,880 WE'RE ALWAYS A LITTLE BIT OVERLY 193 00:07:10,880 --> 00:07:11,360 AMBITIOUS. 194 00:07:11,360 --> 00:07:12,880 WE'RE A SMALL INSTITUTE BUT 195 00:07:12,880 --> 00:07:14,440 THINK WE CAN HAVE A LOT OF 196 00:07:14,440 --> 00:07:14,720 IMPACT. 197 00:07:14,720 --> 00:07:16,840 SO THAT'S KIND OF ONE OF OUR 198 00:07:16,840 --> 00:07:17,280 CHARACTERISTICS. 199 00:07:17,280 --> 00:07:19,560 I THINK OF OUR ENTIRE FIELD AND 200 00:07:19,560 --> 00:07:20,760 OUR WHOLE COMMUNITY. 201 00:07:20,760 --> 00:07:24,840 SO, I'M NOW GOING TO GO AHEAD 202 00:07:24,840 --> 00:07:26,560 AND SHARING THE SCREEN. 203 00:07:26,560 --> 00:07:32,960 I DON'T WANT TO WASTE TIME WITH 204 00:07:32,960 --> 00:07:37,600 MY PREAMBLE. 205 00:07:37,600 --> 00:07:38,560 OKAY. 206 00:07:38,560 --> 00:07:42,480 THANK YOU SO MUCH, DAVID, AS 207 00:07:42,480 --> 00:07:45,040 DAVID POINTED OUT THIS IS A 208 00:07:45,040 --> 00:07:45,880 REALLY HUGE TEAM EFFORT, THANKS 209 00:07:45,880 --> 00:07:50,400 TO DAVE FOR ALL THE WORK HE DOES 210 00:07:50,400 --> 00:07:53,320 IN ORGANIZATION. 211 00:07:53,320 --> 00:07:55,080 PAM AND ALICIA WHO WE'LL TORTURE 212 00:07:55,080 --> 00:07:56,800 IF WE DO A LIVE MEETING BUT THEY 213 00:07:56,800 --> 00:07:57,880 ARE FANTASTIC AT THIS AND WE 214 00:07:57,880 --> 00:08:01,360 APPRECIATE THEIR WORK. 215 00:08:01,360 --> 00:08:02,680 SENIOR LEADERSHIP, JILL WILL 216 00:08:02,680 --> 00:08:07,200 HELP ME ON COUNCIL SLIDES, AND 217 00:08:07,200 --> 00:08:09,200 JASON, RICHARD, CHRIS, ENTIRE 218 00:08:09,200 --> 00:08:10,560 NIBIB CONTRIBUTED TO THESE. 219 00:08:10,560 --> 00:08:13,200 SPEAKING OF TORTURING, ABOUT TWO 220 00:08:13,200 --> 00:08:15,080 WEEKS AGO WE DO -- ABOUT TWO 221 00:08:15,080 --> 00:08:16,800 WEEKS BEFORE COUNCIL MEETING WE 222 00:08:16,800 --> 00:08:19,720 GET TOGETHER AND GO THROUGH 223 00:08:19,720 --> 00:08:20,680 CANDIDATE SLIDES AND REALLY 224 00:08:20,680 --> 00:08:22,480 DISCUSS WHAT MAY GO INTO THE 225 00:08:22,480 --> 00:08:28,000 COUNCIL PRESENTATION AND HAVE AN 226 00:08:28,000 --> 00:08:28,760 INCREDIBLE SLIDE TEAM. 227 00:08:28,760 --> 00:08:31,040 THANK YOU TO THE SLIDE TEAM. 228 00:08:31,040 --> 00:08:36,880 THEY WORK WITH ALL OF OUR STAFF 229 00:08:36,880 --> 00:08:39,560 TO VET IDEAS AND GET THEM INTO 230 00:08:39,560 --> 00:08:41,000 SLIDES AND THEN WE SPEND 231 00:08:41,000 --> 00:08:41,880 ANYWHERE BETWEEN AN 232 00:08:41,880 --> 00:08:43,480 HOUR-AND-A-HALF AND TWO HOURS A 233 00:08:43,480 --> 00:08:45,080 COUPLE WEEKS BEFORE COUNCIL 234 00:08:45,080 --> 00:08:45,960 GOING THROUGH THESE. 235 00:08:45,960 --> 00:08:49,440 SO THANK YOU TO THE TEAM. 236 00:08:49,440 --> 00:08:52,360 AND AS I MENTIONED, WE LOOK 237 00:08:52,360 --> 00:08:53,920 FORWARD TO MEETING IN PERSON, 238 00:08:53,920 --> 00:08:54,720 HOPEFULLY. 239 00:08:54,720 --> 00:08:57,480 AND TO INSPIRE YOU, I HAVE A 240 00:08:57,480 --> 00:09:02,640 NICE PICTURE FROM THE BOLGER 241 00:09:02,640 --> 00:09:04,880 CONFERENCE CENTER, OUR 242 00:09:04,880 --> 00:09:06,240 TRADITIONAL MEETING LOCATION, 243 00:09:06,240 --> 00:09:08,320 CLOSE TO THE NIH LOCATION BUT 244 00:09:08,320 --> 00:09:12,160 DOES NOT HAVE SECURITY AND THEY 245 00:09:12,160 --> 00:09:15,040 HAVE MUCH BETTER OATMEAL RAISIN 246 00:09:15,040 --> 00:09:15,880 COOKIES AND PRESENTATION TREATS. 247 00:09:15,880 --> 00:09:17,960 HOPEFULLY WE CAN GET BACK IN 248 00:09:17,960 --> 00:09:22,440 MAY, MAY 16, MARK THAT DATE ON 249 00:09:22,440 --> 00:09:22,760 YOUR CALENDAR. 250 00:09:22,760 --> 00:09:24,640 PAM AND ALISHA WILL BE LEADING 251 00:09:24,640 --> 00:09:30,360 THE EFFORT TO GET US INTO BOLGER 252 00:09:30,360 --> 00:09:31,480 OR POSSIBLY ANOTHER FACILITY. 253 00:09:31,480 --> 00:09:33,280 I HAVE A LOT ON THE AGENDA. 254 00:09:33,280 --> 00:09:36,200 SO MANY I THOUGHT I WOULD PUT AN 255 00:09:36,200 --> 00:09:37,520 OUTLINE TOGETHER SO I'M GOING TO 256 00:09:37,520 --> 00:09:39,600 START WITH WELCOMING OUR NEW 257 00:09:39,600 --> 00:09:40,600 COUNCIL MEMBERS, TRADITIONAL 258 00:09:40,600 --> 00:09:43,440 THING THAT WE DO IN SEPTEMBER AS 259 00:09:43,440 --> 00:09:45,560 WELL AS NIBIB STAFF AND WHAT 260 00:09:45,560 --> 00:09:48,040 EVERYBODY IS ALSO INTERESTED IN, 261 00:09:48,040 --> 00:09:52,280 OUR BUDGET UPDATES. 262 00:09:52,280 --> 00:09:53,520 SO, FIRST CYNTHIA MCCULLOUGH, 263 00:09:53,520 --> 00:09:54,800 WELCOME, CYNTHIA. 264 00:09:54,800 --> 00:09:58,000 MANY OF YOU KNOW CYNTHIA, 265 00:09:58,000 --> 00:10:00,000 PROFESSOR OF MEDICAL PHYSICS AND 266 00:10:00,000 --> 00:10:03,480 BIOMEDICAL ENGINEERING, DIRECTOR 267 00:10:03,480 --> 00:10:06,880 OF MAYO CT CLINICAL INNOVATION 268 00:10:06,880 --> 00:10:09,480 CENTER, USING CF FOR 269 00:10:09,480 --> 00:10:10,640 QUANTITATIVE ASSESSMENT, DISEASE 270 00:10:10,640 --> 00:10:11,480 PROGRESSION AND REGRESSION, 271 00:10:11,480 --> 00:10:13,040 ORGAN FUNCTION, AS WELL AS 272 00:10:13,040 --> 00:10:14,480 METHODS TO QUANTIFY AND REDUCE 273 00:10:14,480 --> 00:10:15,200 PATIENT DOSE. 274 00:10:15,200 --> 00:10:17,600 I HAVE TO SAY WHEN I WAS A 275 00:10:17,600 --> 00:10:19,240 COUNCIL MEMBER I SAW CYNTHIA 276 00:10:19,240 --> 00:10:21,080 GIVE A TALK ON ALL OF THESE 277 00:10:21,080 --> 00:10:22,640 TOPICS AND WAS COMPLETELY BLOWN 278 00:10:22,640 --> 00:10:23,480 AWAY. 279 00:10:23,480 --> 00:10:25,040 I THINK MY FOUNDATIONAL 280 00:10:25,040 --> 00:10:26,800 KNOWLEDGE OF CT ON ALL OF THESE 281 00:10:26,800 --> 00:10:29,200 TOPICS REALLY COMES FROM THAT 282 00:10:29,200 --> 00:10:29,880 PRESENTATION FROM CYNTHIA. 283 00:10:29,880 --> 00:10:32,680 SHE'S A FELLOW OF THE AMERICAN 284 00:10:32,680 --> 00:10:35,280 COLLEGE OF RADIOLOGY AND AAPM, 285 00:10:35,280 --> 00:10:38,280 RECENTLY A RECIPIENT OF MAYO'S 286 00:10:38,280 --> 00:10:39,720 DISTINGUISHED INVESTIGATOR 287 00:10:39,720 --> 00:10:43,760 AWARD. 288 00:10:43,760 --> 00:10:44,920 SO WELCOME, CYNTHIA. 289 00:10:44,920 --> 00:10:47,000 ALSO, DAN IS A PROFESSOR OF 290 00:10:47,000 --> 00:10:49,400 RADIOLOGY AS WELL AS 291 00:10:49,400 --> 00:10:51,080 NEUROSCIENCE AND PHYSIOLOGY AT 292 00:10:51,080 --> 00:10:53,880 NYU IN THEIR SCHOOL OF MEDICINE, 293 00:10:53,880 --> 00:10:55,480 DIRECTOR OF THE SCHWARTZ CENTER 294 00:10:55,480 --> 00:10:56,880 FOR BIOMEDICAL ENGINEERING, VIE 295 00:10:56,880 --> 00:10:59,120 CHAIR FOR RESEARCH AND 296 00:10:59,120 --> 00:11:01,280 RADIOLOGY, HIS RESEARCH HAS 297 00:11:01,280 --> 00:11:02,720 PIONEERED RAPID PARALLEL MRI 298 00:11:02,720 --> 00:11:04,000 TECHNIQUES, BUT HE'S ALSO VERY 299 00:11:04,000 --> 00:11:06,480 WELL KNOWN FOR HIS PIONEERING 300 00:11:06,480 --> 00:11:10,120 WORK IN TECHNOLOGIES AND 301 00:11:10,120 --> 00:11:10,800 COMPUTATIONAL METHODS, IMAGE 302 00:11:10,800 --> 00:11:17,400 ACQUISITION, HE WORKS ON INVERSE 303 00:11:17,400 --> 00:11:18,880 PROBLEMS, COMPRESSED SENSING, 304 00:11:18,880 --> 00:11:20,040 ELECTROMAGNET ISSUE TISSUE 305 00:11:20,040 --> 00:11:21,000 INTERACTION AND INTERPRETATION 306 00:11:21,000 --> 00:11:24,000 OF ISSUES, A.I. AND 307 00:11:24,000 --> 00:11:25,800 MULTI-MODALITY IMAGING AND 308 00:11:25,800 --> 00:11:27,840 PRINCIPAL INVESTIGATOR OF ONE OF 309 00:11:27,840 --> 00:11:29,320 OUR JEWELS IN THE TECHNOLOGY 310 00:11:29,320 --> 00:11:34,680 CROWN P41 CENTER FOR ADVANCED 311 00:11:34,680 --> 00:11:38,360 IMAGING INNOVATION AND RESEARCH. 312 00:11:38,360 --> 00:11:40,360 THIRD IS JOYCE WONG, AND I THINK 313 00:11:40,360 --> 00:11:47,600 EVERYONE KNOWS JOYCE, PROFESSOR 314 00:11:47,600 --> 00:11:48,800 OF BIOMEDICAL ENGINEERING AT 315 00:11:48,800 --> 00:11:50,320 BOSTON UNIVERSITY, RESEARCH IS 316 00:11:50,320 --> 00:11:53,160 BASIC ON STRUCTURE AND MATERIAL 317 00:11:53,160 --> 00:11:56,400 PROPERTIES AND COMPOSITION OF 318 00:11:56,400 --> 00:11:58,080 CELL BIOMERELY ENTER TASTES, 319 00:11:58,080 --> 00:11:59,320 AFFECT CELLULAR PROCESSES AND 320 00:11:59,320 --> 00:12:02,080 TAKES THAT BASIC KNOWLEDGE TO 321 00:12:02,080 --> 00:12:03,480 DESIGN CELL MATERIAL INTERFACES 322 00:12:03,480 --> 00:12:05,800 BOTH TO DETECT AND TREAT 323 00:12:05,800 --> 00:12:06,120 DISEASE. 324 00:12:06,120 --> 00:12:07,880 PRACTICAL APPLICATIONS AS WELL 325 00:12:07,880 --> 00:12:10,920 AS FUNDAMENTAL KNOWLEDGE IN THIS 326 00:12:10,920 --> 00:12:11,680 AREA. 327 00:12:11,680 --> 00:12:16,480 JOYCE IS CURRENTLY PRESIDENT AND 328 00:12:16,480 --> 00:12:19,000 FELL AIMBE, SHE'S A FELLOW OF 329 00:12:19,000 --> 00:12:25,440 THE NATIONAL ACADEMY OF 330 00:12:25,440 --> 00:12:26,560 INVENTORS, BMES, AAAS, IAMBE AND 331 00:12:26,560 --> 00:12:29,080 WON THE SOCIETY FOR BIOMATERIALS 332 00:12:29,080 --> 00:12:30,600 CLEMSON AWARD, IS ACTIVE IN 333 00:12:30,600 --> 00:12:31,600 DIVERSITY ACTIVITIES AND ONE OF 334 00:12:31,600 --> 00:12:32,800 THE INTERESTING THINGS THAT 335 00:12:32,800 --> 00:12:35,080 CAUGHT OUR EYE IS SHE'S THE 336 00:12:35,080 --> 00:12:40,680 INAUGURAL DIRECTOR OF A PROGRAM 337 00:12:40,680 --> 00:12:42,960 CALLED ARROWS, WHICH IS, OH 338 00:12:42,960 --> 00:12:45,200 GOSH, YOU'LL HAVE TO ASK JOYCE, 339 00:12:45,200 --> 00:12:48,200 I FORGOT WHAT IT STANDS FOR. 340 00:12:48,200 --> 00:12:50,720 BUT THIS IS AN ORGANIZATION THAT 341 00:12:50,720 --> 00:12:53,440 IS FOCUSED ON PROMOTING WOMEN IN 342 00:12:53,440 --> 00:12:55,880 STEM AT BOSTON UNIVERSITY, IT'S 343 00:12:55,880 --> 00:12:59,000 I THINK IN MANY WAYS A MODEL FOR 344 00:12:59,000 --> 00:13:01,800 THE TYPES OF PROGRAMS THAT ALL 345 00:13:01,800 --> 00:13:03,640 UNIVERSITIES COULD ADOPT IF 346 00:13:03,640 --> 00:13:04,760 YOU'RE NOT REALLY LAUNCHING A 347 00:13:04,760 --> 00:13:06,480 PROGRAM LIKE THIS. 348 00:13:06,480 --> 00:13:07,280 IT'S REALLY AN IMPORTANT ONE, 349 00:13:07,280 --> 00:13:09,240 AND JOYCE I THINK CAN FILL YOU 350 00:13:09,240 --> 00:13:14,840 IN ON DETAILS OF THAT. 351 00:13:14,840 --> 00:13:18,440 NOW WE HAVE SOME NEW NIBIB STAFF 352 00:13:18,440 --> 00:13:18,960 TO INTRODUCE. 353 00:13:18,960 --> 00:13:23,240 IN THE OFFICE OF SCIENTIFIC 354 00:13:23,240 --> 00:13:26,280 REVIEW, ALEXANDER IS A 355 00:13:26,280 --> 00:13:28,040 SCIENTIFIC REVIEW OFFICER, AND 356 00:13:28,040 --> 00:13:30,280 HE WAS ASSISTANT PROFESSOR IN 357 00:13:30,280 --> 00:13:35,040 DEPARTMENT OF BIOMEDICAL 358 00:13:35,040 --> 00:13:36,080 ENGINEERING AT GEORGE MASON 359 00:13:36,080 --> 00:13:38,800 UNIVERSITY, HAS OVER 30 YEARS OF 360 00:13:38,800 --> 00:13:42,840 BENCH AND COMPUTATIONAL RESEARCH 361 00:13:42,840 --> 00:13:44,480 EXPERIENCE IN NEUROPHYSIOLOGY, 362 00:13:44,480 --> 00:13:45,680 COMPUTATIONAL NEUROSCIENCE, 363 00:13:45,680 --> 00:13:47,680 INFORMATICS, MODELING BIOLOGICAL 364 00:13:47,680 --> 00:13:48,960 SYSTEMS, INFORMATION PROCESSING. 365 00:13:48,960 --> 00:13:54,080 AND HE WILL BE VERY ACTIVE IN 366 00:13:54,080 --> 00:13:54,960 CONTRIBUTING HIS EXPERTISE TO 367 00:13:54,960 --> 00:13:59,080 OUR SPECIAL REVIEWS THAT WE DO 368 00:13:59,080 --> 00:14:01,480 WITHIN NIBIB. 369 00:14:01,480 --> 00:14:05,440 WE ALSO WELCOME LAVANE TERRELL, 370 00:14:05,440 --> 00:14:07,200 EXTRAMURAL SUPPORT ASSISTANT IN 371 00:14:07,200 --> 00:14:09,640 OSR, OVER 15 YEARS OF 372 00:14:09,640 --> 00:14:15,200 PROFESSIONAL EXPERIENCE AND 373 00:14:15,200 --> 00:14:16,080 EXECUTIVE AND PROGRAM 374 00:14:16,080 --> 00:14:18,600 ASSISTANCE, SHE CAME FROM DCU 375 00:14:18,600 --> 00:14:19,680 GOVERNMENT, EXPERIENCE IN 376 00:14:19,680 --> 00:14:21,000 UNDERSTANDING BOTH FEDERAL 377 00:14:21,000 --> 00:14:26,240 STRUCTURE AS WELL AS LOCAL 378 00:14:26,240 --> 00:14:27,320 GOVERNMENT STRUCTURES. 379 00:14:27,320 --> 00:14:29,200 SHAWN MULVANEY IS A NEW PROGRAM 380 00:14:29,200 --> 00:14:32,600 OFFICER DIVISION OF HEALTH 381 00:14:32,600 --> 00:14:33,240 INFORMATICS TECHNOLOGIES, SHAWN 382 00:14:33,240 --> 00:14:35,560 SPENT MORE THAN TWO DECADES AS A 383 00:14:35,560 --> 00:14:37,320 SCIENTIST AT U.S. NAVAL RESEARCH 384 00:14:37,320 --> 00:14:41,240 LAB WORKING ON CHEMICAL AND 385 00:14:41,240 --> 00:14:41,960 BIOLOGICAL SENSING, AND HE 386 00:14:41,960 --> 00:14:44,560 SPECIALIZES IN A LOT OF REALLY 387 00:14:44,560 --> 00:14:46,640 IMPORTANT AREAS THAT ARE 388 00:14:46,640 --> 00:14:54,040 DIRECTLY IMPACTING OUR RADx 389 00:14:54,040 --> 00:14:55,240 PROGRAM, BIOTIC, ABIOTIC 390 00:14:55,240 --> 00:14:57,120 INTERFACE, DEVICE PROTOTYPING, A 391 00:14:57,120 --> 00:14:59,960 HUGE AMOUNT OF EXPERIENCE 392 00:14:59,960 --> 00:15:01,040 BUILDING BIOSENSOR PLATFORMS 393 00:15:01,040 --> 00:15:03,600 WHICH HE'S DONE FOR FIRST 394 00:15:03,600 --> 00:15:05,680 RESPONDERS AND ALSO USE BY WAR 395 00:15:05,680 --> 00:15:08,640 FIGHTERS. 396 00:15:08,640 --> 00:15:12,080 AS I MENTIONED HE'S HAD LOTS OF 397 00:15:12,080 --> 00:15:13,080 EXPERIENCE WITH RADx, ON 398 00:15:13,080 --> 00:15:17,080 DETAIL AND NOW AS A MEMBER OF 399 00:15:17,080 --> 00:15:18,320 NIBIB, IMPACTFUL, A LARGE 400 00:15:18,320 --> 00:15:19,440 PORTFOLIO OF AT LEAST TEN 401 00:15:19,440 --> 00:15:23,040 TECHNOLOGIES, A MEMBER OF OUR 402 00:15:23,040 --> 00:15:25,080 FUNDING PANEL. 403 00:15:25,080 --> 00:15:26,880 SO DAVID GUTEKUNST IS IN THE 404 00:15:26,880 --> 00:15:27,960 DIVISION OF INTERDISCIPLINARY 405 00:15:27,960 --> 00:15:28,560 TRAINING. 406 00:15:28,560 --> 00:15:31,040 HIS EXPERTISE IS IN MOVEMENT 407 00:15:31,040 --> 00:15:33,440 SCIENCE AND BIOMECHANICS, FOCUS 408 00:15:33,440 --> 00:15:35,280 ON LOWER EXTREMITY 409 00:15:35,280 --> 00:15:35,800 MUSCULOSKELETAL INJURY 410 00:15:35,800 --> 00:15:38,440 MECHANISMS, PRIOR TO THIS HE WAS 411 00:15:38,440 --> 00:15:39,880 ASSISTANT PROFESSOR IN 412 00:15:39,880 --> 00:15:41,000 BIOMEDICAL ENGINEERING AT THE 413 00:15:41,000 --> 00:15:43,680 MAYO CLINIC, AFTER THAT 414 00:15:43,680 --> 00:15:44,520 ASSISTANT PROFESSOR IN 415 00:15:44,520 --> 00:15:47,000 DEPARTMENT OF PHYSICAL THERAPY 416 00:15:47,000 --> 00:15:49,080 AT ST. LOUIS UNIVERSITY. 417 00:15:49,080 --> 00:15:53,280 HE JOINED NIH AS AAAS FELLOW IN 418 00:15:53,280 --> 00:15:57,760 NICHD'S NATIONAL CENTER FOR 419 00:15:57,760 --> 00:15:59,080 REHABILITATION RESEARCH, AND 420 00:15:59,080 --> 00:16:02,480 DAVID'S FACULTY AS WELL AS 421 00:16:02,480 --> 00:16:03,160 RESEARCH EXPERIENCE AND 422 00:16:03,160 --> 00:16:04,480 UNDERGRADUATE AND Ph.D. 423 00:16:04,480 --> 00:16:05,640 TRAINING IN BIOMEDICAL 424 00:16:05,640 --> 00:16:09,480 ENGINEERING FROM WASH U ARE A 425 00:16:09,480 --> 00:16:12,400 PERFECT FIT FOR OUR TRAINING 426 00:16:12,400 --> 00:16:12,680 POSITION. 427 00:16:12,680 --> 00:16:15,080 WE HAVE THREE MORE STAFF TO 428 00:16:15,080 --> 00:16:17,360 INTRODUCE, AND THIS IS ALL THREE 429 00:16:17,360 --> 00:16:19,080 JOINED THE DIVISION OF DISCOVERY 430 00:16:19,080 --> 00:16:26,280 SCIENCE AND TECHNOLOGY, THE 431 00:16:26,280 --> 00:16:29,720 FIRST JERMONT CHEN HAS A 432 00:16:29,720 --> 00:16:30,840 BACKGROUND IN CHEMISTRY, AIR 433 00:16:30,840 --> 00:16:32,120 FORCE ACADEMY GRADUATE, WIDE 434 00:16:32,120 --> 00:16:33,560 RANGE OF EXPERIENCES SPANNING 435 00:16:33,560 --> 00:16:35,280 FROM WORKING AS ASSISTANT 436 00:16:35,280 --> 00:16:37,120 PROFESSOR IN DEPARTMENT OF 437 00:16:37,120 --> 00:16:38,880 CHEMISTRY AT THE AIR FORCE 438 00:16:38,880 --> 00:16:41,280 ACADEMY, TO SERVING AS FUELS AND 439 00:16:41,280 --> 00:16:44,200 ENERGY BRANCH CHIEF IN THE 440 00:16:44,200 --> 00:16:45,160 AEROSPACE SYSTEMS DIRECTORATE OF 441 00:16:45,160 --> 00:16:47,440 THE AIR FORCE RESEARCH 442 00:16:47,440 --> 00:16:47,720 LABORATORY. 443 00:16:47,720 --> 00:16:51,040 MOST RECENTLY HE WAS DEPUTY 444 00:16:51,040 --> 00:16:54,240 DIRECTOR AND INTERNATIONAL 445 00:16:54,240 --> 00:16:56,280 PROGRAM IN INTERNATIONAL OFFICE 446 00:16:56,280 --> 00:16:58,600 IN TOKYO WHERE HE BUILT A 447 00:16:58,600 --> 00:17:02,520 PORTFOLIO IN SYNTHETIC BIOLOGY 448 00:17:02,520 --> 00:17:03,680 ROBOTICS, NANOSCIENCE, AN IDEAL 449 00:17:03,680 --> 00:17:07,080 FIT FOR OUR DIVISION. 450 00:17:07,080 --> 00:17:08,240 JESSICA FALCONE COMPLETED 451 00:17:08,240 --> 00:17:09,960 Ph.D. FAIRLY RECENTLY AT 452 00:17:09,960 --> 00:17:12,880 GEORGIA TECH IN NEURAL 453 00:17:12,880 --> 00:17:13,480 ENGINEERING STUDYING BRAIN 454 00:17:13,480 --> 00:17:16,200 ELECTRODES, POSTDOC AT THE 455 00:17:16,200 --> 00:17:25,480 FEINSTEIN INSTITUTE FOR MEDICAL 456 00:17:25,480 --> 00:17:26,240 RESEARCH WORKING ON VAGAS 457 00:17:26,240 --> 00:17:27,880 NERVES, COMES FROM CITY WHERE 458 00:17:27,880 --> 00:17:30,480 SHE WAS WORKING AT TUCKER DAVIS, 459 00:17:30,480 --> 00:17:34,560 THAT BUILDS RESEARCH SYSTEMS FOR 460 00:17:34,560 --> 00:17:35,160 NEUROSCIENTISTS. 461 00:17:35,160 --> 00:17:37,960 FINALLY LEE SIMS IS JOINING 462 00:17:37,960 --> 00:17:41,200 NIBIB AS A AAAS FELLOW, SCIENCE 463 00:17:41,200 --> 00:17:43,400 AND TECHNOLOGY POLICY FELLOW FOR 464 00:17:43,400 --> 00:17:43,680 AAAS. 465 00:17:43,680 --> 00:17:47,480 PRIOR TO THIS HE WORKED AS 466 00:17:47,480 --> 00:17:50,160 TECHNICAL ADVISER FOR USAID, 467 00:17:50,160 --> 00:17:51,400 AGENCY FOR INTERNATIONAL 468 00:17:51,400 --> 00:17:52,480 DEVELOPMENT, SUPPORTED A GLOBAL 469 00:17:52,480 --> 00:17:54,000 HEALTH TECHNOLOGY RESEARCH AND 470 00:17:54,000 --> 00:17:55,920 DEVELOPMENT PROGRAM EFFORT THERE 471 00:17:55,920 --> 00:17:57,720 SO BRINGS THAT PERSPECTIVE TO 472 00:17:57,720 --> 00:17:59,080 OUR WORK. 473 00:17:59,080 --> 00:18:01,080 BACKGROUND IS IN BIOENGINEERING 474 00:18:01,080 --> 00:18:03,000 AND EPIDEMIOLOGY WITH RESEARCH 475 00:18:03,000 --> 00:18:05,880 FOCUSING ON APPLICATION OF 476 00:18:05,880 --> 00:18:07,160 BIOMATERIALS FOR NANOTECHNOLOGY, 477 00:18:07,160 --> 00:18:08,760 TRANSPORT AND DIFFUSION MODELING 478 00:18:08,760 --> 00:18:11,000 OF NANOPARTICLE SYSTEMS, HAS A 479 00:18:11,000 --> 00:18:12,800 GREAT TECHNICAL BACKGROUND, ALSO 480 00:18:12,800 --> 00:18:14,080 STRONG GLOBAL HEALTH INTEREST. 481 00:18:14,080 --> 00:18:16,280 IF WE WERE LIVE IN PERSON WE 482 00:18:16,280 --> 00:18:19,320 WOULD GIVE EVERYONE A ROUND OF 483 00:18:19,320 --> 00:18:21,160 APPLAUSE, BUT THINK OF DOING 484 00:18:21,160 --> 00:18:22,600 THAT VIRTUALLY, WE'RE SO HAPPY 485 00:18:22,600 --> 00:18:26,880 TO HAVE ALL OF YOU JOIN NIBIB. 486 00:18:26,880 --> 00:18:29,480 YOU BRING A WEALTH OF EXPERTISE, 487 00:18:29,480 --> 00:18:31,280 UNIQUE EXPERIENCES, LOTS OF 488 00:18:31,280 --> 00:18:32,640 ENERGY, CREATIVITY AND DRIVE 489 00:18:32,640 --> 00:18:34,480 THAT WILL CONTINUE TO INVIGORATE 490 00:18:34,480 --> 00:18:39,880 THE INSTITUTE AND OUR FIELD. 491 00:18:39,880 --> 00:18:43,280 SO, QUICK BUDGET UPDATE, THE FY 492 00:18:43,280 --> 00:18:44,240 23 APPROPRIATIONS JUST A 493 00:18:44,240 --> 00:18:47,840 SUMMARY, THIS IS THE SENATE 494 00:18:47,840 --> 00:18:50,640 PROPOSED, NIH OVER ALL HAS A 495 00:18:50,640 --> 00:18:53,080 LITTLE OVER $48 BILLION. 496 00:18:53,080 --> 00:18:54,680 THAT'S AN INCREASE OF $3 BILLION 497 00:18:54,680 --> 00:18:56,240 OVER FY 22 LEVELS. 498 00:18:56,240 --> 00:18:58,040 BUT IF YOU'VE BEEN FOLLOWING 499 00:18:58,040 --> 00:18:59,720 BUDGET DISCUSSIONS, THIS IS JUST 500 00:18:59,720 --> 00:19:01,360 THE SENATE PROPOSED BUDGET SO WE 501 00:19:01,360 --> 00:19:03,560 DON'T KNOW WHICH BUDGET WILL BE 502 00:19:03,560 --> 00:19:05,680 ENACTED AND THAT COULD TAKE 503 00:19:05,680 --> 00:19:06,880 QUITE SOME TIME. 504 00:19:06,880 --> 00:19:07,880 WITHIN THIS BUDGET THERE'S AN 505 00:19:07,880 --> 00:19:10,680 AVERAGE OF ABOUT A LITTLE OVER 506 00:19:10,680 --> 00:19:13,000 3% INCREASE FOR INSTITUTES AND 507 00:19:13,000 --> 00:19:14,520 CENTERS, AND THAT'S EXACTLY THE 508 00:19:14,520 --> 00:19:18,640 AMOUNT THAT WAS CALLED OUT THAT 509 00:19:18,640 --> 00:19:21,080 NIBIB WOULD RECEIVE A 3.1% 510 00:19:21,080 --> 00:19:21,320 INCREASE. 511 00:19:21,320 --> 00:19:23,680 AND WE DID ANNOUNCE THIS LAST 512 00:19:23,680 --> 00:19:26,480 TIME BUT HAVEN'T FINALIZED BUT 513 00:19:26,480 --> 00:19:30,600 OUR FY 22 R01 PAYLINE IS 19th 514 00:19:30,600 --> 00:19:36,200 PERCENTILE AND 24 PER CENT FOR 515 00:19:36,200 --> 00:19:40,960 NEW INVESTIGATORS. 516 00:19:40,960 --> 00:19:42,920 THIS IS ESPECIALLY FOR OUR NEW 517 00:19:42,920 --> 00:19:44,760 JOINING COUNCIL MEMBERS. 518 00:19:44,760 --> 00:19:46,720 YOU HAVEN'T SEEN THIS KIND OF 519 00:19:46,720 --> 00:19:49,480 SLIDE BEFORE, BUT ALL OF OUR 520 00:19:49,480 --> 00:19:52,760 ONGOING COUNCIL MEMBERS ARE 521 00:19:52,760 --> 00:19:55,680 QUITE FAMILIAR WITH THIS IMPACT 522 00:19:55,680 --> 00:19:57,600 THAT SUPPLEMENTAL APPROPRIATIONS 523 00:19:57,600 --> 00:19:59,720 HAVE HAD ON NIBIB. 524 00:19:59,720 --> 00:20:03,680 WE KIND OF HAVE TWO NIBIBs. 525 00:20:03,680 --> 00:20:07,120 THERE'S WHAT WE CALL NIBIB 1, 526 00:20:07,120 --> 00:20:09,240 CORE PROGRAMS, AND THEY ARE 527 00:20:09,240 --> 00:20:10,880 FUNDED BY THESE CONGRESSIONAL 528 00:20:10,880 --> 00:20:11,280 APPROPRIATIONS. 529 00:20:11,280 --> 00:20:12,640 YOU CAN SEE THE GROWTH THERE 530 00:20:12,640 --> 00:20:17,680 OVER THE YEARS HAS BEEN FAIRLY 531 00:20:17,680 --> 00:20:22,800 FLAT IN FY 18, $377 MILLION, FY 532 00:20:22,800 --> 00:20:24,000 22 IT'S $422 MILLION. 533 00:20:24,000 --> 00:20:26,480 SO THERE HAS BEEN SOME GROWTH 534 00:20:26,480 --> 00:20:28,160 BUT IT'S MODEST. 535 00:20:28,160 --> 00:20:32,240 AND THEN WITH COVID, AND THE 536 00:20:32,240 --> 00:20:32,880 SUPPLEMENTAL APPROPRIATIONS, 537 00:20:32,880 --> 00:20:34,600 MOST PROMINENTLY IN THE FOURTH 538 00:20:34,600 --> 00:20:36,920 CONGRESSIONAL SUPPLEMENT WHICH 539 00:20:36,920 --> 00:20:41,000 CAME APRIL 24, 2020, NIH OVERALL 540 00:20:41,000 --> 00:20:45,920 RECEIVED $1.5 BILLION, $500 541 00:20:45,920 --> 00:20:47,200 MILLION DIRECTLY TO NIBIB, WE'VE 542 00:20:47,200 --> 00:20:49,080 RECEIVED SEVERAL OTHER SOURCES 543 00:20:49,080 --> 00:20:49,720 IN ADDITION TO THIS $500 MILLION 544 00:20:49,720 --> 00:20:52,760 FROM THE OFFICE OF THE DIRECTOR 545 00:20:52,760 --> 00:20:55,360 AND OTHER AGENCIES, SO OVER THE 546 00:20:55,360 --> 00:20:58,480 PAST THREE YEARS NIBIB HAS 547 00:20:58,480 --> 00:21:01,280 RECEIVED AN ADDITIONAL TOTAL 548 00:21:01,280 --> 00:21:02,480 SUPPLEMENTAL FUNDING OF OVER 549 00:21:02,480 --> 00:21:03,760 $1.7 BILLION, AND THOSE HAVE 550 00:21:03,760 --> 00:21:06,000 BEEN -- FUNDS HAVE BEEN DIRECTED 551 00:21:06,000 --> 00:21:08,080 TO OUR PANDEMIC RESPONSE. 552 00:21:08,080 --> 00:21:10,080 SO NIBIB HAS BEEN CENTRAL IN 553 00:21:10,080 --> 00:21:10,960 THAT RESPONSE, AND WE'VE BEEN 554 00:21:10,960 --> 00:21:14,280 ABLE TO HAVE AN IMPACT IN 555 00:21:14,280 --> 00:21:15,320 IMAGING AND ARTIFICIAL 556 00:21:15,320 --> 00:21:16,440 INTELLIGENCE, IN VITRO 557 00:21:16,440 --> 00:21:19,600 DIAGNOSTICS, AND DIGITAL HEALTH 558 00:21:19,600 --> 00:21:20,200 PLATFORMS WHICH WE'LL UPDATE 559 00:21:20,200 --> 00:21:22,120 EVERYONE ON LATER IN THE 560 00:21:22,120 --> 00:21:22,520 PRESENTATION. 561 00:21:22,520 --> 00:21:23,120 SO, OUR RETURNING COUNCIL 562 00:21:23,120 --> 00:21:25,080 MEMBERS ARE VERY FAMILIAR WITH 563 00:21:25,080 --> 00:21:27,080 THIS, BUT FOR OUR NEW COUNCIL 564 00:21:27,080 --> 00:21:30,720 MEMBERS THIS HAS BEEN THE BIG 565 00:21:30,720 --> 00:21:32,200 STORY BEHIND WHAT'S HAPPENED TO 566 00:21:32,200 --> 00:21:36,120 NIBIB OVER THE PAST FEW YEARS. 567 00:21:36,120 --> 00:21:41,480 SO LET'S TALK ABOUT NIBIB-1, 568 00:21:41,480 --> 00:21:42,880 SPECIAL FUNDING OPPORTUNITIES. 569 00:21:42,880 --> 00:21:44,640 AND YOU ALL HAVE BEEN 570 00:21:44,640 --> 00:21:46,960 FOLLOWING -- THIS IS QUITE AN 571 00:21:46,960 --> 00:21:50,560 AMAZING STORY LED BY RANDY KING, 572 00:21:50,560 --> 00:21:51,280 ALZHEIMER'S DISEASE 573 00:21:51,280 --> 00:21:52,080 ADMINISTRATIVE SUPPLEMENTS, 574 00:21:52,080 --> 00:21:53,920 HOPEFULLY YOU'RE GOING BACK AND 575 00:21:53,920 --> 00:21:56,600 COMMUNICATING THIS TO YOUR 576 00:21:56,600 --> 00:21:56,880 COLLEAGUES. 577 00:21:56,880 --> 00:21:58,280 THIS IS, AGAIN, A NOTICE HAS 578 00:21:58,280 --> 00:21:59,800 BEEN POSTED. 579 00:21:59,800 --> 00:22:01,240 FIRST AVAILABLE DUE DATE IS THE 580 00:22:01,240 --> 00:22:02,680 1st OF OCTOBER. 581 00:22:02,680 --> 00:22:05,280 THESE ARE ONE YEAR OF SUPPORT 582 00:22:05,280 --> 00:22:08,720 REQUESTS, NO MORE THAN $250 IN 583 00:22:08,720 --> 00:22:09,640 DIRECT COSTS, BUT WHAT'S SO 584 00:22:09,640 --> 00:22:12,160 BEAUTIFUL ABOUT THIS IS YOU CAN 585 00:22:12,160 --> 00:22:15,320 HAVE A GRAD WORKING ON A 586 00:22:15,320 --> 00:22:17,000 TECHNOLOGY DEVELOPMENT IN OTHER 587 00:22:17,000 --> 00:22:20,480 AREAS AND BE COMPETITIVE FOR 588 00:22:20,480 --> 00:22:21,280 SUPPLEMENT THAT ALLOWS YOU TO 589 00:22:21,280 --> 00:22:23,560 TAKE WHAT YOU'RE WORKING ON, THE 590 00:22:23,560 --> 00:22:24,440 TECHNOLOGIES YOU'RE DEVELOPING, 591 00:22:24,440 --> 00:22:27,600 AND APPLY THEM TO ALZHEIMER'S 592 00:22:27,600 --> 00:22:29,440 DISEASE, ENCOURAGE YOU TO SPEAK 593 00:22:29,440 --> 00:22:31,880 WITH RANDY, A QUICK SNAPSHOT 594 00:22:31,880 --> 00:22:35,880 HERE, THE IMPACT HAS BEEN QUITE 595 00:22:35,880 --> 00:22:36,520 ASTOUNDING, MORE THAN $16 596 00:22:36,520 --> 00:22:39,440 MILLION OVER THE SIX YEARS THAT 597 00:22:39,440 --> 00:22:42,920 WE'VE BEEN ACTIVE, THAT THIS 598 00:22:42,920 --> 00:22:43,760 SUPPLEMENT PROGRAM HAS BEEN 599 00:22:43,760 --> 00:22:44,280 GOING ON. 600 00:22:44,280 --> 00:22:45,960 YOU CAN SEE THE AMOUNT IN TOTAL 601 00:22:45,960 --> 00:22:47,840 HAS BEEN CREEPING UP A LITTLE 602 00:22:47,840 --> 00:22:52,720 BIT EACH YEAR, SO IN 2022, 603 00:22:52,720 --> 00:22:54,320 $3.4 MILLION AWARDED. 604 00:22:54,320 --> 00:22:56,520 NUMBER OF SUPPLEMENTS IS 605 00:22:56,520 --> 00:23:00,480 CONSTANT, RANGING BETWEEN ABOUT 606 00:23:00,480 --> 00:23:01,120 14 AND 16 AWARDS. 607 00:23:01,120 --> 00:23:05,920 BRAIN FLISH INITIATIVE, YOU 608 00:23:05,920 --> 00:23:07,040 KNOW THERE ARE SUBSTANTIAL 609 00:23:07,040 --> 00:23:08,680 INCREASES IN BRAIN INITIATIVE 610 00:23:08,680 --> 00:23:09,160 FUNDING PARTICULARLY IN 611 00:23:09,160 --> 00:23:11,640 TECHNOLOGY DEVELOPMENT THAT ARE 612 00:23:11,640 --> 00:23:11,920 SLATED. 613 00:23:11,920 --> 00:23:14,120 AND SCHUMAN LANG HAS LED THIS 614 00:23:14,120 --> 00:23:14,920 EFFORT. 615 00:23:14,920 --> 00:23:23,080 THIS IS A NEW RFA PUBLISHED FOR 616 00:23:23,080 --> 00:23:24,400 NON-INVASIVE IMAGING 617 00:23:24,400 --> 00:23:26,680 DEVELOPMENT, UG3 AND UH3 618 00:23:26,680 --> 00:23:28,040 MECHANISM, I DEFINITELY 619 00:23:28,040 --> 00:23:29,520 RECOMMEND YOU SPEAK WITH SHUMIN 620 00:23:29,520 --> 00:23:31,400 IF YOU HAVE AN INTEREST. 621 00:23:31,400 --> 00:23:33,280 THE GOAL IS TO SUPPORT TEAM 622 00:23:33,280 --> 00:23:36,040 BASED DEVELOPMENT, VALIDATION OF 623 00:23:36,040 --> 00:23:38,200 INNOVATIVE NON-INVASIVE IMAGING 624 00:23:38,200 --> 00:23:39,280 TECHNOLOGIES THAT STUDY -- THAT 625 00:23:39,280 --> 00:23:41,920 IMPACT STUDY OF BRAIN FUNCTION 626 00:23:41,920 --> 00:23:42,880 AND CONNECTIVITY. 627 00:23:42,880 --> 00:23:46,880 THE KEY DATES TO KEEP IN MIND 628 00:23:46,880 --> 00:23:48,680 ARE -- WELL, IT'S ALREADY OPEN, 629 00:23:48,680 --> 00:23:51,200 SEPTEMBER 13, DUE DATES FOR THE 630 00:23:51,200 --> 00:23:52,880 APPLICATIONS ARE OCTOBER 13. 631 00:23:52,880 --> 00:23:59,040 THIS IS REALLY RIGHT IN LINE 632 00:23:59,040 --> 00:24:07,400 WITH THE TECHNOLOGIC ACTIVITY 633 00:24:07,400 --> 00:24:09,240 OF OUR COMMUNITY. 634 00:24:09,240 --> 00:24:10,840 THIS IS THE TERM YOU'VE BEEN 635 00:24:10,840 --> 00:24:12,520 HEARING ABOUT CONSTANTLY FOR THE 636 00:24:12,520 --> 00:24:15,800 LAST FEW YEARS, THE POINT OF 637 00:24:15,800 --> 00:24:16,400 CARE TECHNOLOGY RESEARCH 638 00:24:16,400 --> 00:24:17,480 NETWORK. 639 00:24:17,480 --> 00:24:20,760 THIS IS NOW OFFICIALLY REISSUED. 640 00:24:20,760 --> 00:24:22,960 AND POCTRN AS MOST OF YOU KNOW 641 00:24:22,960 --> 00:24:25,680 IS THE FOUNDATION OF THE ENTIRE 642 00:24:25,680 --> 00:24:27,240 RADx PROGRAM, IT'S THE 643 00:24:27,240 --> 00:24:29,200 INSPIRATION FOR WHICH WE 644 00:24:29,200 --> 00:24:32,480 ACTUALLY CAN CONDUCT OR WHAT WE 645 00:24:32,480 --> 00:24:35,040 LIKE TO SAY RADx-IFY OTHER 646 00:24:35,040 --> 00:24:36,520 PARTS OF NIBIB. 647 00:24:36,520 --> 00:24:38,080 IT'S A FIVE-YEAR PROGRAM AND WE 648 00:24:38,080 --> 00:24:39,880 HAVE A RECORD NUMBER OF 649 00:24:39,880 --> 00:24:42,000 INSTITUTES AND CENTERS THAT ARE 650 00:24:42,000 --> 00:24:43,640 INVOLVED THIS YEAR, SEVEN 651 00:24:43,640 --> 00:24:49,240 DIFFERENT I.C.s WILL SUPPORT 652 00:24:49,240 --> 00:24:49,800 APPLICATION-ORIENTED POCTRN 653 00:24:49,800 --> 00:24:52,880 SIDES, AND THERE ARE MORE 654 00:24:52,880 --> 00:24:53,520 DETAILS WITH TECHNICAL 655 00:24:53,520 --> 00:24:55,480 ASSISTANCE WEBINAR THAT ARE 656 00:24:55,480 --> 00:24:57,880 AVAILABLE AND TIFFANI LASH IS 657 00:24:57,880 --> 00:25:00,000 PROGRAM LEADER WHO HAS DEVELOPED 658 00:25:00,000 --> 00:25:01,280 AND DESIGNED THIS PROGRAM, SO 659 00:25:01,280 --> 00:25:04,440 PLEASE DON'T HESITATE TO GET IN 660 00:25:04,440 --> 00:25:06,120 TOUCH WITH TIFFANI, PARTICULARLY 661 00:25:06,120 --> 00:25:11,080 AS WE'RE LOOKING TO EXPAND THESE 662 00:25:11,080 --> 00:25:17,440 SEVEN I.C.s AND ENGAGEMENT IN 663 00:25:17,440 --> 00:25:18,000 APPLICATION-ORIENTED AREAS. 664 00:25:18,000 --> 00:25:25,160 MED TECH IS ANOTHER EXAMPLE OF 665 00:25:25,160 --> 00:25:25,520 RADx-IFICATION. 666 00:25:25,520 --> 00:25:28,200 THE BIG NEWS, WE CAN'T ANNOUNCE 667 00:25:28,200 --> 00:25:31,480 THE HUBS QUITE YET, THEY WILL 668 00:25:31,480 --> 00:25:34,320 HAVE A SOLICITATION WHICH CAN BE 669 00:25:34,320 --> 00:25:35,760 ACCESSED THROUGH THIS URL WHICH 670 00:25:35,760 --> 00:25:37,840 IS NOT LIVE YET BUT THE KEY 671 00:25:37,840 --> 00:25:40,560 THING IS TO SORT OF RAISE YOUR 672 00:25:40,560 --> 00:25:43,080 VISIBILITY HERE BECAUSE THE 673 00:25:43,080 --> 00:25:45,360 SOLICITATION WILL OPEN SEPTEMBER 674 00:25:45,360 --> 00:25:47,440 27, WITH PRE-PROPOSALS DUE 675 00:25:47,440 --> 00:25:48,160 OCTOBER 25. 676 00:25:48,160 --> 00:25:51,360 THIS WILL PROVIDE UP TO 500K PER 677 00:25:51,360 --> 00:25:52,680 YEAR FOR SUPPORT, UP TO FOUR 678 00:25:52,680 --> 00:25:54,480 YEARS, THERE WILL BE UP TO 30 679 00:25:54,480 --> 00:25:55,400 NEW AWARDS PER YEAR. 680 00:25:55,400 --> 00:26:00,280 SEE THIS IS A REALLY POTENTIALLY 681 00:26:00,280 --> 00:26:01,840 HUGELY IMPACTFUL PROGRAM, 682 00:26:01,840 --> 00:26:03,200 CONTACT MIKE WOLFSON WHO HAS 683 00:26:03,200 --> 00:26:05,720 THOUGHT THROUGH ALL OF THE 684 00:26:05,720 --> 00:26:08,280 COMPLEXITY AND STEPS OF THIS 685 00:26:08,280 --> 00:26:11,040 PROGRAM AND INSPIRED OUR 686 00:26:11,040 --> 00:26:12,880 BLUEPRINT COLLEAGUES TO ACTUALLY 687 00:26:12,880 --> 00:26:15,360 ADOPT THIS NEW MODEL, WHICH IS 688 00:26:15,360 --> 00:26:19,880 THE FIRST EXAMPLE ACROSS THE NIH 689 00:26:19,880 --> 00:26:22,120 OF TRANSFERRING ATTRIBUTES OF 690 00:26:22,120 --> 00:26:24,880 RADx TO ESTABLISHED PROGRAMS. 691 00:26:24,880 --> 00:26:29,520 ON THAT TOPIC, WE HAVE A NEW 692 00:26:29,520 --> 00:26:30,920 MECHANISM IN RADx TECH FOR 693 00:26:30,920 --> 00:26:32,480 MATERNAL HEALTH, SO THIS NOW 694 00:26:32,480 --> 00:26:37,320 ADOPTS THE FORMAL NAME OF RADx 695 00:26:37,320 --> 00:26:37,520 TECH. 696 00:26:37,520 --> 00:26:39,240 AS WE'VE BEEN DISCUSSING, IT IS 697 00:26:39,240 --> 00:26:42,200 HOW DO YOU CREATIVELY APPLY 698 00:26:42,200 --> 00:26:44,480 PRINCIPLES OF ACCELERATION AND 699 00:26:44,480 --> 00:26:47,320 SUPPORT THAT CAN HELP FACILITATE 700 00:26:47,320 --> 00:26:48,880 COMMERCIALIZATION AND REGULATORY 701 00:26:48,880 --> 00:26:54,480 AUTHORIZATION, AND RAPID 702 00:26:54,480 --> 00:26:55,120 MANUFACTURING OF TECHNOLOGY, OUR 703 00:26:55,120 --> 00:26:56,720 FIRST ATTEMPT TO DO IT ON A 704 00:26:56,720 --> 00:26:58,880 SCALE DIFFERENT FROM WHAT IS 705 00:26:58,880 --> 00:27:00,520 TYPICALLY DONE WITH TRADITIONAL 706 00:27:00,520 --> 00:27:01,000 GRANTS. 707 00:27:01,000 --> 00:27:06,240 AND WITH AN ENTIRELY NEW 708 00:27:06,240 --> 00:27:15,760 MECHANISTIC STRUCTURE THAT 709 00:27:15,760 --> 00:27:18,520 TAYLOR GILILAN, WE HAVE A 710 00:27:18,520 --> 00:27:19,880 PROBLEM LOOKING AT DISPARITIES 711 00:27:19,880 --> 00:27:21,000 IN MATERNITY CARE DESERTS WHERE 712 00:27:21,000 --> 00:27:23,600 THERE ARE HIGHER RATES OF 713 00:27:23,600 --> 00:27:25,680 MATERNAL MORTALITY AND SEVERE 714 00:27:25,680 --> 00:27:27,520 MATERNAL MORTALITY, THIS IS A 715 00:27:27,520 --> 00:27:30,400 TOPIC WE'VE WORKED ON WITH 716 00:27:30,400 --> 00:27:31,600 NICHD, ACTUALLY FOR SEVERAL 717 00:27:31,600 --> 00:27:34,120 MONTHS, AND THE SOLUTION HERE IS 718 00:27:34,120 --> 00:27:36,400 TO LEVERAGE OUR INNOVATION 719 00:27:36,400 --> 00:27:37,640 FUNNEL PROCESS TO ACCELERATE 720 00:27:37,640 --> 00:27:40,000 INNOVATION AND POINT OF CARE AND 721 00:27:40,000 --> 00:27:42,320 HOME-BASED DIAGNOSTIC AND REMOTE 722 00:27:42,320 --> 00:27:43,080 SENSING TECHNOLOGIES. 723 00:27:43,080 --> 00:27:44,720 SO THERE ARE A NUMBER OF 724 00:27:44,720 --> 00:27:46,240 CONDITIONS THAT THIS WOULD 725 00:27:46,240 --> 00:27:49,680 DIRECTLY APPLY TO, AND LOTS OF 726 00:27:49,680 --> 00:27:50,400 REALLY UNIQUE EXAMPLES OF 727 00:27:50,400 --> 00:27:52,880 TECHNOLOGIES THAT ARE QUITE 728 00:27:52,880 --> 00:27:54,880 ROBUST AND I'LL GET TO SOME OF 729 00:27:54,880 --> 00:27:56,800 THOSE LATER WHEN I PRESENT WHAT 730 00:27:56,800 --> 00:28:00,200 IS IN A SENSE A PREP FOR THIS 731 00:28:00,200 --> 00:28:01,520 PROGRAM, THE NATIONAL TECHNOLOGY 732 00:28:01,520 --> 00:28:04,120 ACCELERATOR CHALLENGE, AND THOSE 733 00:28:04,120 --> 00:28:05,800 AWARDS WHICH WE DID JUST 734 00:28:05,800 --> 00:28:07,880 RECENTLY ANNOUNCED ABOUT A MONTH 735 00:28:07,880 --> 00:28:08,040 AGO. 736 00:28:08,040 --> 00:28:11,440 BUT THESE MAY INCLUDE WEARABLE 737 00:28:11,440 --> 00:28:14,920 DEVICES, AT-HOME DIAGNOSTICS 738 00:28:14,920 --> 00:28:15,320 WITH BIOSPECIMENS, 739 00:28:15,320 --> 00:28:16,960 SMARTPHONE-ENABLED TOOLS, POINT 740 00:28:16,960 --> 00:28:19,520 OF CARE DEVOICES, INTEGRATED 741 00:28:19,520 --> 00:28:20,680 SENSOR TECHNOLOGIES. 742 00:28:20,680 --> 00:28:22,960 AND THE STRUCTURE OF THE PROGRAM 743 00:28:22,960 --> 00:28:24,960 IS REALLY KIND OF REVOLUTIONARY 744 00:28:24,960 --> 00:28:29,640 AND BRILLIANT THANKS TO TAYLOR. 745 00:28:29,640 --> 00:28:32,080 IT'S A MILESTONE-BASED PRIZE 746 00:28:32,080 --> 00:28:34,560 AWARD SYSTEM THAT EMULATES WHAT 747 00:28:34,560 --> 00:28:37,640 WE DO WITH RADx, BUT ALLOWS US 748 00:28:37,640 --> 00:28:40,360 TO USE A PRIZE COMPETITION 749 00:28:40,360 --> 00:28:43,080 STRUCTURE TO MAKE THESE AWARDS 750 00:28:43,080 --> 00:28:44,840 AND KEEP ACCELERATING THE 751 00:28:44,840 --> 00:28:45,840 MOVEMENT OF THE TECHNOLOGIES 752 00:28:45,840 --> 00:28:47,120 THROUGH THE INNOVATION FUNNEL. 753 00:28:47,120 --> 00:28:49,560 I WON'T GO INTO DETAILS OF ALL 754 00:28:49,560 --> 00:28:52,080 OF WHERE THE ARROWS GO AND THE 755 00:28:52,080 --> 00:28:54,120 MEANING BEHIND ALL OF THAT. 756 00:28:54,120 --> 00:28:56,360 TAYLOR, YOU CAN CONTACT HIM FOR 757 00:28:56,360 --> 00:28:57,360 MORE INFORMATION ABOUT THIS. 758 00:28:57,360 --> 00:28:59,880 THE IDEA IS THAT TEAMS OF 759 00:28:59,880 --> 00:29:02,800 INNOVATORS WHO HAVE LOW BARRIER 760 00:29:02,800 --> 00:29:05,440 TO ENTRY FOR THEIR CONCEPTS, 761 00:29:05,440 --> 00:29:06,760 PROTOTYPE TECHNOLOGY 762 00:29:06,760 --> 00:29:08,720 DESCRIPTIONS AND PLANS, THEY ARE 763 00:29:08,720 --> 00:29:10,840 REVIEWED VERY QUICKLY AND MOVE 764 00:29:10,840 --> 00:29:13,560 INTO VARIOUS STAGES OF ANALYSIS 765 00:29:13,560 --> 00:29:14,480 AND POTENTIAL FUNDING. 766 00:29:14,480 --> 00:29:17,440 WHAT I SHOULD MENTION HERE I 767 00:29:17,440 --> 00:29:20,200 DIDN'T POINT THIS OUT, TOTAL 768 00:29:20,200 --> 00:29:22,480 PRIZES HERE ARE $8 MILLION, AND 769 00:29:22,480 --> 00:29:25,560 THIS IS WHERE WE'VE REALLY 770 00:29:25,560 --> 00:29:26,480 LEVERAGED OUR RELATIONSHIP WITH 771 00:29:26,480 --> 00:29:29,400 NICHD, THEY HAVE PROVIDED ALL 772 00:29:29,400 --> 00:29:32,160 THE PRIZE FUNDS AND NIBIB IS 773 00:29:32,160 --> 00:29:33,680 PROVIDING THE EXPERTISE AND ALL 774 00:29:33,680 --> 00:29:35,760 OF THE SURROUNDING STRUCTURES TO 775 00:29:35,760 --> 00:29:38,280 BE ABLE TO EVALUATE THE 776 00:29:38,280 --> 00:29:40,800 TECHNOLOGIES AND SUPPORT THEM 777 00:29:40,800 --> 00:29:44,400 FOR COMMERCIALIZATION AND 778 00:29:44,400 --> 00:29:44,920 REGULATORY AUTHORIZATION. 779 00:29:44,920 --> 00:29:46,480 THE TIMELINE, THE CHALLENGE WAS 780 00:29:46,480 --> 00:29:48,440 JUST ANNOUNCED ON THE 1st OF 781 00:29:48,440 --> 00:29:49,160 SEPTEMBER. 782 00:29:49,160 --> 00:29:50,640 AND WE EXPECT THAT REGISTRATION 783 00:29:50,640 --> 00:29:52,280 AND SUBMISSION PORTAL WILL OPEN 784 00:29:52,280 --> 00:29:54,320 IN A COUPLE DAYS ON THE 15th 785 00:29:54,320 --> 00:29:55,480 OF SEPTEMBER. 786 00:29:55,480 --> 00:29:57,680 WITH A NOVEMBER 1 SUBMISSION 787 00:29:57,680 --> 00:29:57,960 DEADLINE. 788 00:29:57,960 --> 00:29:58,960 THERE ARE A LOT OF LINKS HERE 789 00:29:58,960 --> 00:30:01,200 BUT I THINK YOU CAN SEE THIS ON 790 00:30:01,200 --> 00:30:02,760 OUR WEBSITE. 791 00:30:02,760 --> 00:30:03,760 THERE'S AN INFORMATIONAL WEBINAR 792 00:30:03,760 --> 00:30:05,480 THAT WILL BE LAUNCHED ON THE 793 00:30:05,480 --> 00:30:07,880 22nd AT 2 P.M. EASTERN TIME, 794 00:30:07,880 --> 00:30:09,640 AND I DEFINITELY ENCOURAGE YOU 795 00:30:09,640 --> 00:30:13,520 TO CONTACT TAYLOR TO GET MORE 796 00:30:13,520 --> 00:30:14,520 INFORMATION ABOUT THAT. 797 00:30:14,520 --> 00:30:17,840 THIS HAS BEEN BREWING FOR MANY 798 00:30:17,840 --> 00:30:18,600 MONTHS. 799 00:30:18,600 --> 00:30:20,800 IT'S REALLY AN ENTIRELY NEW 800 00:30:20,800 --> 00:30:23,200 PARADIGM, BECAUSE WE'VE BEEN 801 00:30:23,200 --> 00:30:25,280 ABLE TO LEVERAGE THE PRIZE 802 00:30:25,280 --> 00:30:27,480 STRUCTURE IN ORDER TO CREATE A 803 00:30:27,480 --> 00:30:29,920 RADx TYPE OF PROCESS WITH AN 804 00:30:29,920 --> 00:30:30,320 INNOVATION FUNNEL. 805 00:30:30,320 --> 00:30:38,080 SO TAYLOR HAS BEEN THE LEAD, 806 00:30:38,080 --> 00:30:42,680 ALSO WORKING WITH ANTONELLO 807 00:30:42,680 --> 00:30:43,680 PILEGGI, SUPPORT FROM THE OFFICE 808 00:30:43,680 --> 00:30:46,760 OF RESEARCH IN WOMEN'S HEALTH, 809 00:30:46,760 --> 00:30:52,080 NIDDK, EXPERTS ACROSS THE NIBIB 810 00:30:52,080 --> 00:30:53,680 INCLUDING TODD AND TIFFANI, THE 811 00:30:53,680 --> 00:30:54,920 USUAL SUSPECTS WHO HAVE BEEN 812 00:30:54,920 --> 00:31:01,880 INVOLVED IN THE RADx PROGRAM. 813 00:31:01,880 --> 00:31:02,880 AND IT'S A TRULY 814 00:31:02,880 --> 00:31:04,080 INTERDISCIPLINARY EFFORT WITH 815 00:31:04,080 --> 00:31:06,200 MANY DIFFERENT STAKEHOLDERS. 816 00:31:06,200 --> 00:31:09,040 WHAT'S AMAZING ABOUT THIS IS WE 817 00:31:09,040 --> 00:31:11,400 THINK THIS MODEL IS EXTENDIBLE 818 00:31:11,400 --> 00:31:13,280 TO OTHER MAJOR PROBLEMS THAT 819 00:31:13,280 --> 00:31:15,040 OTHER INSTITUTES AND CENTERS ARE 820 00:31:15,040 --> 00:31:15,280 FACING. 821 00:31:15,280 --> 00:31:17,480 WE'RE HOPING TO BE ABLE TO APPLY 822 00:31:17,480 --> 00:31:19,400 THIS NEXT TO CHALLENGES THAT THE 823 00:31:19,400 --> 00:31:21,920 OFFICE OF AIDS RESEARCH IS 824 00:31:21,920 --> 00:31:23,240 LOOKING AND FACING IN 825 00:31:23,240 --> 00:31:28,280 TECHNOLOGIES THEY NEED, ALSO 826 00:31:28,280 --> 00:31:29,320 WORKING WITH NINR, NHLBI, THERE 827 00:31:29,320 --> 00:31:31,680 ARE A LOT OF INTERESTING GROWTH 828 00:31:31,680 --> 00:31:34,680 OPPORTUNITIES FROM CREATING THIS 829 00:31:34,680 --> 00:31:35,800 FUNDAMENTAL NEW STRUCTURE. 830 00:31:35,800 --> 00:31:37,680 SPEAKING OF PARTNERSHIP WITH 831 00:31:37,680 --> 00:31:41,480 NICHD, WE HAVE AN ACTIVE RFI, 832 00:31:41,480 --> 00:31:45,200 INVITING COMMENTS ON PEDIATRIC 833 00:31:45,200 --> 00:31:45,720 MEDICAL DEVICES FORMING A 834 00:31:45,720 --> 00:31:46,760 PUBLIC/PRIVATE PARTNERSHIP. 835 00:31:46,760 --> 00:31:48,800 MANY OF YOU KNOW WHO HAVE BEEN 836 00:31:48,800 --> 00:31:50,880 INVOLVED IN THIS AREA, THIS IS 837 00:31:50,880 --> 00:31:52,440 EXTREMELY DIFFICULT TO DEVELOP 838 00:31:52,440 --> 00:31:56,200 DEVICES AND GET THEM AUTHORIZED 839 00:31:56,200 --> 00:31:58,280 WORKING WITH THE FDA CAN BE 840 00:31:58,280 --> 00:31:59,680 TOUGH IN THIS PARTICULAR AREA. 841 00:31:59,680 --> 00:32:02,920 SO WE'RE HOPING TO ADVANCE THIS, 842 00:32:02,920 --> 00:32:03,520 WE'RE LOOKING FOR COMMENTS, 843 00:32:03,520 --> 00:32:07,320 ULTIMATELY WE HOPE TO BE ABLE TO 844 00:32:07,320 --> 00:32:11,000 RELEASE SOME MECHANISM THAT 845 00:32:11,000 --> 00:32:15,040 WOULD FACILITATE THAT 846 00:32:15,040 --> 00:32:15,960 DEVELOPMENT. 847 00:32:15,960 --> 00:32:17,080 IN HEAL, HELPING END ADDITION 848 00:32:17,080 --> 00:32:18,640 LONG TERM, YOU'RE FAMILIAR WITH 849 00:32:18,640 --> 00:32:21,000 THAT COMMON FUND PROGRAM. 850 00:32:21,000 --> 00:32:22,720 WHEN THAT WAS FIRST CONCEIVED 851 00:32:22,720 --> 00:32:25,000 THERE WAS NOT THAT MUCH SUPPORT 852 00:32:25,000 --> 00:32:26,800 OR EFFORT DIRECTED TOWARDS OUR 853 00:32:26,800 --> 00:32:28,440 COMMUNITY, OUR TECHNOLOGY 854 00:32:28,440 --> 00:32:29,280 DEVELOPMENT COMMUNITY. 855 00:32:29,280 --> 00:32:33,880 BUT THROUGH THE EFFORTS OF MORIA 856 00:32:33,880 --> 00:32:35,880 BITTMANN AND MIKE WOLFSON AND 857 00:32:35,880 --> 00:32:38,280 OTHERS IN NIBIB WE'VE BEEN ABLE 858 00:32:38,280 --> 00:32:41,080 TO GET "HEAL" TO INVEST IN 859 00:32:41,080 --> 00:32:41,760 TECHNOLOGY DEVELOPMENT AND IN 860 00:32:41,760 --> 00:32:44,480 PARTICULAR THIS IS A NEW 861 00:32:44,480 --> 00:32:46,560 INITIATIVE THAT'S AN R 18, 862 00:32:46,560 --> 00:32:48,880 APPLICATION THAT'S OPEN OCTOBER 863 00:32:48,880 --> 00:32:51,360 14, IT'S DUE NOVEMBER 14, THAT 864 00:32:51,360 --> 00:32:54,320 IS SPECIFICALLY ON DIAGNOSTIC 865 00:32:54,320 --> 00:32:55,960 AND THERAPEUTIC DEVICES, FOR 866 00:32:55,960 --> 00:32:57,880 PAIN OR OPIOID USE DISORDER. 867 00:32:57,880 --> 00:32:59,080 IT'S A REALLY UNUSUAL 868 00:32:59,080 --> 00:33:00,960 OPPORTUNITY, DOESN'T COME AREN'T 869 00:33:00,960 --> 00:33:02,240 THAT OFTEN TO OUR COMMUNITY. 870 00:33:02,240 --> 00:33:04,320 I'M HOPING WE'LL BE ABLE TO 871 00:33:04,320 --> 00:33:07,200 RESPOND TO THIS. 872 00:33:07,200 --> 00:33:08,160 IT'S DESIGNED TO DIRECT 873 00:33:08,160 --> 00:33:12,400 DEVELOPMENT OF NEW TECHNOLOGY 874 00:33:12,400 --> 00:33:13,200 AND APPROACHES WHICH WE THINK 875 00:33:13,200 --> 00:33:14,600 OUR COMMUNITY IS BEST SUITED TO 876 00:33:14,600 --> 00:33:15,800 BE ABLE TO ADDRESS. 877 00:33:15,800 --> 00:33:17,480 THERE ARE NO RESTRICTIONS ON 878 00:33:17,480 --> 00:33:18,840 INVASIVENESS. 879 00:33:18,840 --> 00:33:23,640 SO IT DOESN'T HAVE TO BE 880 00:33:23,640 --> 00:33:24,640 COMPLETELY NON-INVASIVE SYSTEM 881 00:33:24,640 --> 00:33:24,880 EITHER. 882 00:33:24,880 --> 00:33:27,040 THIS IS A NEW -- I JUST GOT 883 00:33:27,040 --> 00:33:27,840 THIS, THIS MORNING. 884 00:33:27,840 --> 00:33:30,560 IT'S A NEW ENTRY INTO THE SLIDE 885 00:33:30,560 --> 00:33:30,760 DECK. 886 00:33:30,760 --> 00:33:33,520 I'M ON THE STEERING COMMITTEE 887 00:33:33,520 --> 00:33:35,080 FOR THIS PARTNERSHIP BETWEEN HHS 888 00:33:35,080 --> 00:33:37,120 AND THE AMERICAN SOCIETY OF 889 00:33:37,120 --> 00:33:37,440 NEPHROLOGY. 890 00:33:37,440 --> 00:33:38,560 AND THEY HAVE A PRIZE WHICH SOME 891 00:33:38,560 --> 00:33:43,920 OF YOU MAY BE FAMILIAR WITH, 892 00:33:43,920 --> 00:33:44,600 KIDNEY-X. 893 00:33:44,600 --> 00:33:46,960 THE TRADITIONAL TRACK IN 894 00:33:46,960 --> 00:33:49,200 KIDNEY-X TO BE SUPPORT 895 00:33:49,200 --> 00:33:50,640 DEVELOPMENT OF BIOARTIFICIAL 896 00:33:50,640 --> 00:33:53,400 KIDNEY PROTOTYPE, AND THEY ARE 897 00:33:53,400 --> 00:33:54,280 FUNDING THESE PRIZES FOR 898 00:33:54,280 --> 00:33:55,760 CONTINUED DEVELOPMENT OF THESE 899 00:33:55,760 --> 00:33:57,080 TYPES OF PROTOTYPES. 900 00:33:57,080 --> 00:33:59,600 ONE OF THE KEY CHALLENGES AND 901 00:33:59,600 --> 00:34:02,680 UNMET NEEDS IS TO BEGIN TO 902 00:34:02,680 --> 00:34:09,040 INTRODUCE SOME OF OUR 903 00:34:09,040 --> 00:34:09,560 BIOMATERIALS COMMUNITY, 904 00:34:09,560 --> 00:34:11,040 SYNTHETIC BIOLOGY COMMUNITY IN A 905 00:34:11,040 --> 00:34:12,720 DIRECTED WAY TOWARDS THIS 906 00:34:12,720 --> 00:34:12,960 PROBLEM. 907 00:34:12,960 --> 00:34:16,160 WE'VE BEEN ABLE TO INSPIRE AN 908 00:34:16,160 --> 00:34:18,520 ENTIRELY NEW TRACK, DEVELOPMENT 909 00:34:18,520 --> 00:34:20,840 OF ENABLING COMPONENTS OR TOOLS, 910 00:34:20,840 --> 00:34:23,040 THESE SPEAK DIRECTLY TO OUR 911 00:34:23,040 --> 00:34:23,640 COMMUNITY. 912 00:34:23,640 --> 00:34:24,840 I HOPE WE'LL HAVE SOME 913 00:34:24,840 --> 00:34:25,800 SUBMISSIONS HERE. 914 00:34:25,800 --> 00:34:28,400 THE TOTAL AMOUNT OF PRIZE 915 00:34:28,400 --> 00:34:29,640 FUNDING UP TO $10.5 MILLION, IT 916 00:34:29,640 --> 00:34:31,040 WILL GO QUICKLY BECAUSE IT'S A 917 00:34:31,040 --> 00:34:32,680 PRIZE CHALLENGE. 918 00:34:32,680 --> 00:34:35,080 AND I HOPE YOU CAN HELP 919 00:34:35,080 --> 00:34:37,600 PUBLICIZE WITH YOUR COLLEAGUES, 920 00:34:37,600 --> 00:34:38,280 PARTICULARLY IN THE BIOMATERIALS 921 00:34:38,280 --> 00:34:39,000 FIELD. 922 00:34:39,000 --> 00:34:41,000 ONE OF THE INTERESTING THINGS 923 00:34:41,000 --> 00:34:42,720 ABOUT TRACK TWO WE'VE BEEN ABLE 924 00:34:42,720 --> 00:34:47,000 TO GET IN IS PREVIOUS EXPERIENCE 925 00:34:47,000 --> 00:34:48,440 WITH KIDNEY RESEARCH 926 00:34:48,440 --> 00:34:49,240 BIOARTIFICIAL KIDNEYS IS NOT 927 00:34:49,240 --> 00:34:50,920 NECESSARILY SO ONE OF THE GOALS 928 00:34:50,920 --> 00:34:53,480 IS TO DRAW NEW PEOPLE IN, INTO 929 00:34:53,480 --> 00:34:57,200 THE COMMUNITY, AND REALLY 930 00:34:57,200 --> 00:34:58,000 INVIGORATE THE ACTIVITIES. 931 00:34:58,000 --> 00:34:59,880 SO I'M GOING TO ANNOUNCE A FEW 932 00:34:59,880 --> 00:35:02,800 RESULTS OF GRANT AND PRIZE 933 00:35:02,800 --> 00:35:04,040 COMPETITIONS NOW THAT I THINK 934 00:35:04,040 --> 00:35:05,680 WE'VE ALL BEEN FOLLOWING AND 935 00:35:05,680 --> 00:35:07,280 LOOKING FORWARD TO SEEING. 936 00:35:07,280 --> 00:35:10,280 YOU'VE HEARD ABOUT OUR R01 937 00:35:10,280 --> 00:35:12,320 FOCUSING ON REDUCING HEALTH 938 00:35:12,320 --> 00:35:14,440 DISPARITIES, SO OUR ENTIRE TEAM 939 00:35:14,440 --> 00:35:17,080 HAS BEEN WORKING REALLY HARD TO 940 00:35:17,080 --> 00:35:20,000 MAKE THESE AWARDS IN FY 22, IN 941 00:35:20,000 --> 00:35:23,160 TIME FOR US TO PRESENT THIS TO 942 00:35:23,160 --> 00:35:23,400 COUNCIL. 943 00:35:23,400 --> 00:35:26,320 IF YOU NOTICE, THE TIME, IT WAS 944 00:35:26,320 --> 00:35:28,080 FIRST DUE FEBRUARY 11, SO HERE 945 00:35:28,080 --> 00:35:30,160 WE ARE ONLY SEVEN MONTHS LATER, 946 00:35:30,160 --> 00:35:31,480 THREE APPLICATIONS HAVE BEEN 947 00:35:31,480 --> 00:35:32,320 FUNDED. 948 00:35:32,320 --> 00:35:34,440 AND I THINK YOU'LL RECOGNIZE THE 949 00:35:34,440 --> 00:35:36,840 TOPICS OF THE AWARDS AS 950 00:35:36,840 --> 00:35:37,920 LONGSTANDING CHALLENGES AND 951 00:35:37,920 --> 00:35:42,960 PROBLEMS IN OUR FIELD. 952 00:35:42,960 --> 00:35:49,720 ONE IS IN BIAS-FREE PULSE 953 00:35:49,720 --> 00:35:53,560 OXIMETRY, SO THEY CAN BE 954 00:35:53,560 --> 00:35:54,880 CORRECTED WORKING WITHOUT 955 00:35:54,880 --> 00:35:56,800 PIGMENTATION AND PROVIDE 956 00:35:56,800 --> 00:35:57,480 ACCURATE READINGS. 957 00:35:57,480 --> 00:35:59,120 MANY PEOPLE POINTED OUT THIS 958 00:35:59,120 --> 00:36:00,880 CRITICAL PROBLEM INCLUDING A 959 00:36:00,880 --> 00:36:02,160 FANTASTIC EDITORIAL PIECE 960 00:36:02,160 --> 00:36:05,280 WRITTEN BY OUR COUNCIL MEMBER 961 00:36:05,280 --> 00:36:07,080 GILDA BARABINO ON THAT TOPIC 962 00:36:07,080 --> 00:36:08,600 FAIRLY RECENTLY. 963 00:36:08,600 --> 00:36:13,800 SECOND ONE IS IN HEP C. 964 00:36:13,800 --> 00:36:18,720 THERE ARE NO POINT OF CARE RAPID 965 00:36:18,720 --> 00:36:19,880 ANTIGEN HEP C DIAGNOSTICS. 966 00:36:19,880 --> 00:36:21,840 THIS WOULD SUPPORT THE 967 00:36:21,840 --> 00:36:22,280 DEVELOPMENT OF THOSE. 968 00:36:22,280 --> 00:36:24,280 THERE ARE SOMEWHERE BETWEEN TWO 969 00:36:24,280 --> 00:36:26,840 AND THREE MILLION PEOPLE IN THE 970 00:36:26,840 --> 00:36:28,480 UNITED STATES WHO HAVE HEP C. 971 00:36:28,480 --> 00:36:30,160 THESE NUMBERS OF COURSE ARE EVEN 972 00:36:30,160 --> 00:36:33,000 LARGER IN THE DEVELOPING WORLD. 973 00:36:33,000 --> 00:36:37,800 THIS WOULD BE A REALLY DRAMATIC 974 00:36:37,800 --> 00:36:39,880 TRANSFORMATION, MANY OF THEM ARE 975 00:36:39,880 --> 00:36:41,800 IN COMMUNITIES WHERE THERE'S 976 00:36:41,800 --> 00:36:43,560 SIGNIFICANT HEALTH DISPARITIES. 977 00:36:43,560 --> 00:36:44,680 WHAT'S QUITE SPECTACULAR IF IT 978 00:36:44,680 --> 00:36:46,880 CAN COME TO PASS AND BE 979 00:36:46,880 --> 00:36:48,320 DEVELOPED IS THAT THERE IS A 980 00:36:48,320 --> 00:36:52,800 CURE FOR HEP C. 981 00:36:52,800 --> 00:36:55,560 SO, THIS CAN COMBINE THE NOTION 982 00:36:55,560 --> 00:36:57,800 OF TESTS AND TREATMENT. 983 00:36:57,800 --> 00:36:58,440 THESE WILL PARTNER TOGETHER AND 984 00:36:58,440 --> 00:37:00,880 I THINK THIS WILL BE A MAJOR 985 00:37:00,880 --> 00:37:02,960 GROWTH AREA IN THE DEVELOPMENT 986 00:37:02,960 --> 00:37:05,480 OF DIAGNOSTICS BOTH WITH HEP C 987 00:37:05,480 --> 00:37:07,120 AND OTHER PATHOGENS. 988 00:37:07,120 --> 00:37:10,160 AND FINALLY, THE THIRD ONE IS IN 989 00:37:10,160 --> 00:37:13,280 THE AREA OF PREVENTING DEATH IN 990 00:37:13,280 --> 00:37:15,280 THE UNDERSERVED MINORITY 991 00:37:15,280 --> 00:37:16,960 POPULATION FROM OPIOID OVERDOSE. 992 00:37:16,960 --> 00:37:20,040 THIS IS A CONTINUOUS REALTIME 993 00:37:20,040 --> 00:37:21,680 NON-INVASIVE CO2 MONITOR THAT 994 00:37:21,680 --> 00:37:23,960 CAN POTENTIALLY IMPACT THAT IN A 995 00:37:23,960 --> 00:37:24,600 VERY SIGNIFICANT WAY. 996 00:37:24,600 --> 00:37:26,800 THOSE ARE THE FIRST THREE 997 00:37:26,800 --> 00:37:27,680 APPLICATIONS FUNDED. 998 00:37:27,680 --> 00:37:28,720 WE'LL KEEP UPDATING YOU ON THE 999 00:37:28,720 --> 00:37:30,280 PROGRESS OF ALL OF THESE AND 1000 00:37:30,280 --> 00:37:32,600 WE'RE REALLY EXCITED. 1001 00:37:32,600 --> 00:37:36,320 I SHOULD REMIND YOU THIS IS A 1002 00:37:36,320 --> 00:37:37,880 PARTNERSHIP WITH NIMHD, MINORITY 1003 00:37:37,880 --> 00:37:39,080 HEALTH AND DISPARITIES 1004 00:37:39,080 --> 00:37:39,480 INSTITUTES. 1005 00:37:39,480 --> 00:37:41,800 THAT WAS AT THE ORIGINAL 1006 00:37:41,800 --> 00:37:42,320 CONCEPTION. 1007 00:37:42,320 --> 00:37:44,120 WE WANTED TO PARTNER WITH THEM 1008 00:37:44,120 --> 00:37:45,800 AND BRING THEM INTO OUR 1009 00:37:45,800 --> 00:37:46,080 COMMUNITY. 1010 00:37:46,080 --> 00:37:47,800 THEY WILL ALSO BE AWARDING SOME 1011 00:37:47,800 --> 00:37:48,040 GRANTS. 1012 00:37:48,040 --> 00:37:49,720 WE DON'T KNOW HOW MANY YET BUT 1013 00:37:49,720 --> 00:37:53,920 THEY WILL BE COMING IN FISCAL 1014 00:37:53,920 --> 00:37:54,480 YEAR 23. 1015 00:37:54,480 --> 00:37:57,760 THIS IS JUST A QUICK SNAPSHOT TO 1016 00:37:57,760 --> 00:37:59,480 UPDATE YOU ON BRIDGE TO 1017 00:37:59,480 --> 00:38:00,840 ARTIFICIAL INTELLIGENCE, THE 1018 00:38:00,840 --> 00:38:02,960 COMMON FUND INITIATIVE. 1019 00:38:02,960 --> 00:38:05,480 OUR LEADER IS GRACE PENG, AND I 1020 00:38:05,480 --> 00:38:06,680 UNDERSTAND THAT A PRESS RELEASE 1021 00:38:06,680 --> 00:38:07,680 SHOULD BE COMING OUT TODAY. 1022 00:38:07,680 --> 00:38:09,720 I HAVEN'T HAD A CHANCE TO CHECK 1023 00:38:09,720 --> 00:38:11,480 THE NIH WEBSITE TO SEE IF THAT 1024 00:38:11,480 --> 00:38:12,880 DID COME OUT. 1025 00:38:12,880 --> 00:38:14,680 SO, WE ENCOURAGE YOU TO TAKE A 1026 00:38:14,680 --> 00:38:14,880 LOOK. 1027 00:38:14,880 --> 00:38:16,920 THE ANNOUNCEMENT OF THE WINNERS 1028 00:38:16,920 --> 00:38:19,240 WHICH WE'VE ALL BEEN WAITING FOR 1029 00:38:19,240 --> 00:38:23,920 IN KEY AREAS FOR ALL OF THESE 1030 00:38:23,920 --> 00:38:24,760 NEW DATASET DEVELOPMENT 1031 00:38:24,760 --> 00:38:26,000 CHALLENGES SHOULD BE COMING OUT 1032 00:38:26,000 --> 00:38:29,680 EITHER TODAY OR VERY SOON 1033 00:38:29,680 --> 00:38:31,000 THEREAFTER. 1034 00:38:31,000 --> 00:38:32,560 ANOTHER MAJOR PROGRAM WHICH IS A 1035 00:38:32,560 --> 00:38:33,520 PRIZE CHALLENGE PROGRAM AND ALL 1036 00:38:33,520 --> 00:38:35,000 OF YOU HAVE BEEN FOLLOWING THIS, 1037 00:38:35,000 --> 00:38:38,360 I THINK THIS IS KIND OF OUR 1038 00:38:38,360 --> 00:38:40,080 SIGNATURE PROGRAM TO SUPPORT 1039 00:38:40,080 --> 00:38:42,720 STUDENTS IN TRAINING AND HELP 1040 00:38:42,720 --> 00:38:45,600 PEOPLE LATCH ON TO PROMISING AND 1041 00:38:45,600 --> 00:38:48,000 MAJOR CHALLENGES FOR THEIR 1042 00:38:48,000 --> 00:38:52,680 ENTIRE CAREERS ARE THE DEBUT 1043 00:38:52,680 --> 00:38:56,040 AWARDS DESIGNED BY BIOMEDICAL 1044 00:38:56,040 --> 00:38:59,280 UNDERGRADUATE TEAMS CHALLENGE 1045 00:38:59,280 --> 00:39:12,960 LED BY NEYNEP ERIM AND DAVE GU 1046 00:39:12,960 --> 00:39:14,280 TENKUNST. 1047 00:39:14,280 --> 00:39:15,200 THIS WE'RE REHAD 73 1048 00:39:15,200 --> 00:39:20,320 APPLICATIONS, 456 OPPORTUNITIES 1049 00:39:20,320 --> 00:39:22,120 AT 44 UNIVERSITIES, 21 STATES, 3 1050 00:39:22,120 --> 00:39:23,720 FOREIGN COUNTRIES, QUITE 1051 00:39:23,720 --> 00:39:24,440 EXTENSIVE. 1052 00:39:24,440 --> 00:39:27,240 WE ALSO HAVE FOR UNIQUE AWARDS 1053 00:39:27,240 --> 00:39:29,760 THAT OTHER INSTITUTES HAVE 1054 00:39:29,760 --> 00:39:31,160 SUPPORTED AT $15,000 EACH FROM 1055 00:39:31,160 --> 00:39:35,000 THE OFFICE OF AIDS RESEARCH, 1056 00:39:35,000 --> 00:39:39,840 FROM NIMHD, NATIONAL CANCER 1057 00:39:39,840 --> 00:39:42,320 INSTITUTE, AND NICHD'S NCMRR, 1058 00:39:42,320 --> 00:39:44,520 REHABILITATIVE AND ASSISTIVE 1059 00:39:44,520 --> 00:39:46,680 TECHNOLOGIES PRIZE. 1060 00:39:46,680 --> 00:39:48,480 VENTUREWELL HAS A DESIGNED PRIZE 1061 00:39:48,480 --> 00:39:49,480 AN EXCELLENCE PRIZE. 1062 00:39:49,480 --> 00:39:52,680 WHAT I'M GOING TO DO NOW IS TELL 1063 00:39:52,680 --> 00:39:55,880 YOU ABOUT SOME OF THESE AWARD 1064 00:39:55,880 --> 00:39:57,440 WINNERS. 1065 00:39:57,440 --> 00:40:06,480 THE FIRST PRIZE IS IN EQUINOX, A 1066 00:40:06,480 --> 00:40:09,360 PULSE OXIMETER, ADDRESSING THAT 1067 00:40:09,360 --> 00:40:11,800 ISSUE OF DISPARITIES WITH PUTS 1068 00:40:11,800 --> 00:40:14,080 OXIMETRY THAT R01 DISPARITY 1069 00:40:14,080 --> 00:40:15,440 WINNER JUST RECEIVED. 1070 00:40:15,440 --> 00:40:19,120 AND WE HAVE A SECOND PLACE AND 1071 00:40:19,120 --> 00:40:22,200 THIRD PLACE AWARD, TO STANFORD 1072 00:40:22,200 --> 00:40:25,800 AND TO COLUMBIA, AT-HOME 1073 00:40:25,800 --> 00:40:29,960 DIAGNOSTICS FOR STREPTOCOCCUS, A 1074 00:40:29,960 --> 00:40:32,440 SIMPLE TOOL THAT QUANTIFIES 1075 00:40:32,440 --> 00:40:34,720 CERVICAL STIFFNESS TO DETERMINE 1076 00:40:34,720 --> 00:40:37,080 RISK OF PRE-TERM BIRTH. 1077 00:40:37,080 --> 00:40:39,480 AN AWARD CEREMONY AT BMES ON 1078 00:40:39,480 --> 00:40:42,520 FRIDAY, BETWEEN 3:00 AND 4:30 1079 00:40:42,520 --> 00:40:43,240 CENTRAL TIME. 1080 00:40:43,240 --> 00:40:44,480 I ENCOURAGE YOU IF YOU'RE THERE 1081 00:40:44,480 --> 00:40:46,600 TO COME TO THE AWARDS CEREMONY 1082 00:40:46,600 --> 00:40:48,200 BUT I'M GOING TO GIVE A PREVIEW 1083 00:40:48,200 --> 00:40:50,480 OF THE VIDEO FROM OUR FIRST 1084 00:40:50,480 --> 00:40:53,000 PLACE PRIZE WINNER. 1085 00:40:53,000 --> 00:41:00,040 >> HI, WE'RE TEAM EQUINOX AIMING 1086 00:41:00,040 --> 00:41:04,680 TO PREVENT HYPOXEMIA IN DARKER 1087 00:41:04,680 --> 00:41:05,120 SKINNED PATIENTS. 1088 00:41:05,120 --> 00:41:05,680 OXIMETERS ARE CRITICAL 1089 00:41:05,680 --> 00:41:06,760 INDICATORS OF HEALTH. 1090 00:41:06,760 --> 00:41:10,080 THE NEED FOR THESE DEVICES HAS 1091 00:41:10,080 --> 00:41:15,360 BEEN RAPIDLY INCREASED DURING 1092 00:41:15,360 --> 00:41:16,560 THE PANDEMIC, HOSPITAL READ 1093 00:41:16,560 --> 00:41:18,800 OXIMETERS ARE BIAS FOR PATIENTS 1094 00:41:18,800 --> 00:41:20,840 WITH DARKER SKIN TONES. 1095 00:41:20,840 --> 00:41:21,800 CONSEQUENTLY MEDICAL PROVIDERS 1096 00:41:21,800 --> 00:41:24,440 NEED A MORE ACCURATE METHOD TO 1097 00:41:24,440 --> 00:41:25,640 MEASURE LEVELS FOR INDIVIDUALS 1098 00:41:25,640 --> 00:41:27,480 WITH DARKER SKIN TONES TO 1099 00:41:27,480 --> 00:41:30,840 PREVENT DELAYS IN DIAGNOSIS OF 1100 00:41:30,840 --> 00:41:31,440 LOW BLOOD OXYGEN. 1101 00:41:31,440 --> 00:41:39,680 LET'S TAKE A LOOK AT HOW PULSE 1102 00:41:39,680 --> 00:41:41,040 OXI METER BIAS CAN AFFECT THE 1103 00:41:41,040 --> 00:41:41,520 PATIENT. 1104 00:41:41,520 --> 00:41:43,920 ONLY AFTER A DELAY OF UP TO 16 1105 00:41:43,920 --> 00:41:55,480 HOURS WILL THE PULSE OXIMETER 1106 00:41:55,480 --> 00:41:55,720 MEASURE. 1107 00:41:55,720 --> 00:41:57,680 >> NOT ONLY ARE THEY INACCURATE 1108 00:41:57,680 --> 00:42:01,480 FOR DARKER SKIN TONED PATIENTS, 1109 00:42:01,480 --> 00:42:02,280 IT'S IMPACTFUL IN LOW- AND 1110 00:42:02,280 --> 00:42:02,920 MIDDLE-INCOME COUNTRIES WITH A 1111 00:42:02,920 --> 00:42:04,280 HIGH POPULATION. 1112 00:42:04,280 --> 00:42:05,680 THE MOST EFFECTIVE COUNTRIES 1113 00:42:05,680 --> 00:42:08,760 DON'T CURRENTLY HAVE RESOURCES 1114 00:42:08,760 --> 00:42:11,040 TO DEPLOY THEM. 1115 00:42:11,040 --> 00:42:11,920 TAKEN TOGETHER THESE 1116 00:42:11,920 --> 00:42:17,080 DISCREPANCIES CREATED A PERFECT 1117 00:42:17,080 --> 00:42:18,400 STORM, AFFECT DIAGNOSES 1118 00:42:18,400 --> 00:42:18,840 WORLDWIDE. 1119 00:42:18,840 --> 00:42:20,680 OUR SOLUTION COMBINES INNOVATION 1120 00:42:20,680 --> 00:42:22,000 IN HARDWARE AND SOFTWARE TO 1121 00:42:22,000 --> 00:42:23,480 ACCOUNT FOR SKIN TONE DIFFERENCE 1122 00:42:23,480 --> 00:42:31,840 AND ADDRESS BIAS FOUND IN 1123 00:42:31,840 --> 00:42:33,680 EXISTING PULSE OXIMETER. 1124 00:42:33,680 --> 00:42:45,520 >> WE USE SENSOR TO ACCOUNT FOR 1125 00:42:45,520 --> 00:42:45,920 DIVERSITY. 1126 00:42:45,920 --> 00:42:48,240 >> EQUINOX IS DESIGNED TO BE 1127 00:42:48,240 --> 00:42:48,840 COMPETITIVE IN LOW-RESOURCE 1128 00:42:48,840 --> 00:42:50,760 SETTINGS WE HOPE TO OPERATE IN. 1129 00:42:50,760 --> 00:42:53,680 $25, THE CURRENT DESIGN CAN BE 1130 00:42:53,680 --> 00:42:57,480 MADE FOR WELL UNDER THE W.H.O. 1131 00:42:57,480 --> 00:42:59,680 RECOMMENDED $40 FOR MARKET 1132 00:42:59,680 --> 00:43:00,440 PENETRATION. 1133 00:43:00,440 --> 00:43:04,080 IT IS DURABLE AND EASILY 1134 00:43:04,080 --> 00:43:04,400 SANITIZED. 1135 00:43:04,400 --> 00:43:06,800 PROCESSOR IS FAST, UNDER TEN 1136 00:43:06,800 --> 00:43:07,240 SECONDS. 1137 00:43:07,240 --> 00:43:09,080 THE ALGORITHM IS ROBUST AND 1138 00:43:09,080 --> 00:43:10,360 TAKES INTO ACCOUNT LITERATURE 1139 00:43:10,360 --> 00:43:12,760 VALUES USING DATA FROM THOUSANDS 1140 00:43:12,760 --> 00:43:13,680 OF PATIENTS. 1141 00:43:13,680 --> 00:43:19,120 HAVING COMPLETED THE PROTOTYPING 1142 00:43:19,120 --> 00:43:20,240 PHASE WE'RE APPROVED AT JOHNS 1143 00:43:20,240 --> 00:43:23,000 HOPKINS, PLAN TO VALIDATE AND 1144 00:43:23,000 --> 00:43:24,080 IMPROVE CURRENT ALGORITHM USING 1145 00:43:24,080 --> 00:43:31,640 ARTERIAL BLOOD GAS ANALYSIS AND 1146 00:43:31,640 --> 00:43:34,520 WILL SEEK FDA APPROVAL TO 1147 00:43:34,520 --> 00:43:35,880 DELIVER TO LOW-RESOURCE 1148 00:43:35,880 --> 00:43:39,080 SETTINGS. 1149 00:43:39,080 --> 00:43:42,120 IT WILL BRING EFFECTIVE PULSE 1150 00:43:42,120 --> 00:43:43,520 OXIMETERS TO EVERYONE FOR 1151 00:43:43,520 --> 00:43:44,280 EQUITABLE CARE WORLDWIDE. 1152 00:43:44,280 --> 00:43:47,680 THANK YOU FOR YOUR TIME. 1153 00:43:47,680 --> 00:43:51,000 >> SO, PRETTY IMPRESSIVE THAT 1154 00:43:51,000 --> 00:43:53,480 FIRST PLACE WINNER, AND VERY 1155 00:43:53,480 --> 00:43:55,120 RESPONSIVE TO AN URGENT NEED 1156 00:43:55,120 --> 00:44:00,640 THAT WE ALL RECOGNIZE HAS COME 1157 00:44:00,640 --> 00:44:02,240 UP SEVERAL TIMES BUT HASN'T BEEN 1158 00:44:02,240 --> 00:44:03,680 ADEQUATELY SOLVED FROM A 1159 00:44:03,680 --> 00:44:05,280 COMMERCIALIZATION POINT OF VIEW. 1160 00:44:05,280 --> 00:44:07,360 HERE ARE THE OTHER WINNERS OF 1161 00:44:07,360 --> 00:44:07,880 THESE PRIZES. 1162 00:44:07,880 --> 00:44:10,960 I WON'T GO INTO DETAILS ON 1163 00:44:10,960 --> 00:44:11,160 THESE. 1164 00:44:11,160 --> 00:44:12,800 YOU CAN SEE THEM, FULLY LISTED 1165 00:44:12,800 --> 00:44:13,800 ON OUR WEBSITE. 1166 00:44:13,800 --> 00:44:16,280 I ENCOURAGE YOU TO COME TO BMES 1167 00:44:16,280 --> 00:44:18,080 TO HEAR PRESENTATIONS FROM EACH 1168 00:44:18,080 --> 00:44:21,680 OF THESE GROUPS ON THESE PRIZES. 1169 00:44:21,680 --> 00:44:23,400 ANOTHER MAJOR PRIZE CHALLENGE 1170 00:44:23,400 --> 00:44:25,360 THAT WE'VE DONE IN PARTNERSHIP 1171 00:44:25,360 --> 00:44:30,480 WITH NICHD AND OFFICE FOR 1172 00:44:30,480 --> 00:44:34,920 RESEARCH IN WOMEN'S HEALTH IS 1173 00:44:34,920 --> 00:44:38,920 NATIONAL TECHNOLOGY ACCELERATOR 1174 00:44:38,920 --> 00:44:41,560 CHALLENGE, NTAC LED BY TIFFANI 1175 00:44:41,560 --> 00:44:43,120 AND TAYLOR. 1176 00:44:43,120 --> 00:44:44,240 WHAT'S INTERESTING ABOUT THIS 1177 00:44:44,240 --> 00:44:47,920 ONE, WE WERE HOPING THIS COULD 1178 00:44:47,920 --> 00:44:49,360 BE AN APPROACH TO GET PEOPLE 1179 00:44:49,360 --> 00:44:52,400 EXCITED AND SORT OF SEE WHAT THE 1180 00:44:52,400 --> 00:44:56,200 COMMUNITY IS DOING IN DEVELOPING 1181 00:44:56,200 --> 00:44:57,160 TECHNOLOGIES FOR MATERNAL HEALTH 1182 00:44:57,160 --> 00:45:00,840 TO FEED INTO THE RADx FUNNEL 1183 00:45:00,840 --> 00:45:02,880 PROCESS THAT WOULD FOLLOW ON TO 1184 00:45:02,880 --> 00:45:06,480 DEVELOP EVEN MORE TECHNOLOGIES 1185 00:45:06,480 --> 00:45:07,720 AND EXPAND OUR IMPACT AND 1186 00:45:07,720 --> 00:45:08,560 FOOTPRINT IN THE FIELD. 1187 00:45:08,560 --> 00:45:10,880 THAT'S WHAT HAPPENED. 1188 00:45:10,880 --> 00:45:12,960 WE HAVE FOUR MAJOR PRIZE 1189 00:45:12,960 --> 00:45:15,040 CHALLENGE WINNERS. 1190 00:45:15,040 --> 00:45:17,120 THE FIRST ARE IN mHEALTH TOOLS 1191 00:45:17,120 --> 00:45:20,960 THAT ARE LOOKING AT HOME-BASED 1192 00:45:20,960 --> 00:45:22,680 DIAGNOSTICS OF SURGICAL SITE 1193 00:45:22,680 --> 00:45:24,040 INFECTIONS AND ANEMIA. 1194 00:45:24,040 --> 00:45:27,080 WEARABLE SENSOR AND POINT OF 1195 00:45:27,080 --> 00:45:31,040 CARE SENSORS ARE BASED ON BOTH 1196 00:45:31,040 --> 00:45:33,720 ACOUSTIC SENSING, AND OPTICAL 1197 00:45:33,720 --> 00:45:35,880 SENSING, WEARABLE CLOTHING, 1198 00:45:35,880 --> 00:45:38,280 FLEXIBLE PATCHES, COMBINATION OF 1199 00:45:38,280 --> 00:45:39,960 REALLY SOME OF THE BEST 1200 00:45:39,960 --> 00:45:40,960 INCLUDING ELECTRIC CHEMICAL 1201 00:45:40,960 --> 00:45:43,680 SENSING, SOME BEST APPROACHES IN 1202 00:45:43,680 --> 00:45:45,760 OUR FIELD. 1203 00:45:45,760 --> 00:45:50,120 AND A VERY EXCITING POINT OF 1204 00:45:50,120 --> 00:45:53,480 CARE DIAGNOSTICS THAT'S ACTUALLY 1205 00:45:53,480 --> 00:46:00,680 MINIATURIZED BUILDING ON ASIG 1206 00:46:00,680 --> 00:46:05,400 WITH APTIMERS THAT CAN DETECT 1207 00:46:05,400 --> 00:46:06,880 PREECLAMPSIA, A WIDE RANGE OF 1208 00:46:06,880 --> 00:46:07,200 TECHNOLOGIES. 1209 00:46:07,200 --> 00:46:09,320 THIS IS OUR PARTNERSHIP WITH 1210 00:46:09,320 --> 00:46:11,520 ALSO THE GATES FOUNDATION, AND 1211 00:46:11,520 --> 00:46:13,280 AS THESE WINNERS PROGRESS IN 1212 00:46:13,280 --> 00:46:14,880 THEIR WORK THEY ARE PARTNERED 1213 00:46:14,880 --> 00:46:18,080 WITH GATES AND PROVIDE SOME 1214 00:46:18,080 --> 00:46:20,680 ADDITIONAL EITHER FUNDING OR 1215 00:46:20,680 --> 00:46:24,080 SUPPORT FOR COMMERCIALIZATION 1216 00:46:24,080 --> 00:46:24,720 AND MANUFACTURING. 1217 00:46:24,720 --> 00:46:27,680 LET ME ANNOUNCE A COUPLE NEW 1218 00:46:27,680 --> 00:46:28,800 PRIZE CHALLENGES AND EVENTS. 1219 00:46:28,800 --> 00:46:30,760 WE HAVE ONE THAT WE'VE BEEN 1220 00:46:30,760 --> 00:46:33,600 WORKING ON WITH THE RADx RAD 1221 00:46:33,600 --> 00:46:36,680 GROUP. 1222 00:46:36,680 --> 00:46:44,160 AND THIS IS LED BY QUI DUAN AND 1223 00:46:44,160 --> 00:46:47,040 TAYLOR GILLILAND, AND THIS WILL 1224 00:46:47,040 --> 00:46:47,600 BE PRIMARILY COMPUTATIONAL, 1225 00:46:47,600 --> 00:46:50,360 DEVELOPMENT OF A.I. AND MM 1226 00:46:50,360 --> 00:46:53,720 MODELS THAT SEEK TO REUSE 1227 00:46:53,720 --> 00:46:57,240 DATABASES IN PARTICULAR, THE N3C 1228 00:46:57,240 --> 00:47:02,000 DATABASE WITH ENORMOUS AMOUNT 1229 00:47:02,000 --> 00:47:03,680 OF CLINICAL AND PATIENT DATA 1230 00:47:03,680 --> 00:47:06,040 FROM COVID PATIENTS OVER AN 1231 00:47:06,040 --> 00:47:06,800 EXTENDED PERIOD OF TIME, 1232 00:47:06,800 --> 00:47:08,680 ESSENTIALLY THE ENTIRE PANDEMIC. 1233 00:47:08,680 --> 00:47:10,760 SO THIS HOPEFULLY WILL STIMULATE 1234 00:47:10,760 --> 00:47:13,720 ACTIVITIES AND HELP DRAW OUT 1235 00:47:13,720 --> 00:47:14,400 SOME NEW INVESTIGATORS, 1236 00:47:14,400 --> 00:47:15,480 OPPORTUNITIES ALSO FOR NEW 1237 00:47:15,480 --> 00:47:32,040 INVESTIGATORS TO PARTICIPATE 1238 00:47:32,040 --> 00:47:33,680 THIS. 1239 00:47:33,680 --> 00:47:38,880 WE HAVE A SYNTHETIC BIOLOGY 1240 00:47:38,880 --> 00:47:40,880 CONSORTIUM MEETING COMING UP. 1241 00:47:40,880 --> 00:47:44,840 THIS MEETING THEME WILL FOCUS ON 1242 00:47:44,840 --> 00:47:46,320 CONTROL THEORY APPROACHES FOR 1243 00:47:46,320 --> 00:47:47,560 SYNTHETIC BIOLOGY TOOLS AND 1244 00:47:47,560 --> 00:47:48,760 TECHNOLOGIES AND PROCESSES. 1245 00:47:48,760 --> 00:47:50,720 THIS IS A FOLLOW-UP FROM 1246 00:47:50,720 --> 00:47:51,480 PREVIOUS MEETINGS, AND I 1247 00:47:51,480 --> 00:47:55,920 ENCOURAGE YOU TO TAKE A LOOK AT 1248 00:47:55,920 --> 00:47:57,280 THE WEBSITE, VIRTUAL INFORMATION 1249 00:47:57,280 --> 00:47:59,480 IS -- IT'S A VIRTUAL MEETING, 1250 00:47:59,480 --> 00:48:02,880 THE INFORMATION IS AVAILABLE ON 1251 00:48:02,880 --> 00:48:05,280 THE SYNTHETIC BIOLOGY WEBSITE. 1252 00:48:05,280 --> 00:48:08,560 GRACE PENG HAS BEEN ACTIVE IN 1253 00:48:08,560 --> 00:48:09,320 LEADING OUR INTERAGENCY MODELING 1254 00:48:09,320 --> 00:48:10,160 AND ANALYSIS GROUP. 1255 00:48:10,160 --> 00:48:11,120 YOU'VE HEARD ABOUT THAT. 1256 00:48:11,120 --> 00:48:14,400 AND ONE OF THE MAJOR CHALLENGES 1257 00:48:14,400 --> 00:48:16,040 THAT TO SOME EXTENT THE BRIDGE 1258 00:48:16,040 --> 00:48:18,800 TO A.I. PROGRAM HAS TAKEN ON BUT 1259 00:48:18,800 --> 00:48:20,400 STILL IS ONE I THINK THAT WE'RE 1260 00:48:20,400 --> 00:48:24,280 DOING TOO MUCH ADMIRING OF AND 1261 00:48:24,280 --> 00:48:26,640 NOT ENOUGH ACTION IS IN DIGITAL 1262 00:48:26,640 --> 00:48:27,080 TWINS. 1263 00:48:27,080 --> 00:48:29,720 AND GRACE HAS BEEN VERY, VERY 1264 00:48:29,720 --> 00:48:31,040 ACTIVE IN BRINGING MULTIPLE 1265 00:48:31,040 --> 00:48:32,680 INSTITUTES AND CENTERS TOGETHER 1266 00:48:32,680 --> 00:48:35,440 AT THE NIH, PARTNERING WITH THE 1267 00:48:35,440 --> 00:48:39,000 DEPARTMENT OF ENERGY, NSF AND 1268 00:48:39,000 --> 00:48:41,760 DoD, AND NOW HAS SHE AND HER 1269 00:48:41,760 --> 00:48:45,160 COLLEAGUES HAVE MANAGED TO BRING 1270 00:48:45,160 --> 00:48:46,960 THE NATIONAL ACADEMIES TOGETHER, 1271 00:48:46,960 --> 00:48:50,760 TO LAUNCH A STUDY, AN 18-MONTH 1272 00:48:50,760 --> 00:48:54,120 ROADMAP STUDY THAT WOULD FOR THE 1273 00:48:54,120 --> 00:48:58,040 FIRST TIME INVOLVE MULTIPLE 1274 00:48:58,040 --> 00:48:59,200 DOMAIN-SPECIFIC WORKSHOPS, SO 1275 00:48:59,200 --> 00:49:00,160 BRINGING DIGITAL TWIN APPROACHES 1276 00:49:00,160 --> 00:49:02,280 WHICH ARE VERY WELL ESTABLISHED 1277 00:49:02,280 --> 00:49:04,480 IN ENGINEERING DATING BACK TO 1278 00:49:04,480 --> 00:49:06,320 THE 50s WITH DEVELOPMENT OF 1279 00:49:06,320 --> 00:49:10,160 FINITE ELEMENT AND FINITE 1280 00:49:10,160 --> 00:49:12,040 DIFFERENCE APPROACHES, IN THE 1281 00:49:12,040 --> 00:49:14,200 DESIGN OF MATERIALS ENGINEERING 1282 00:49:14,200 --> 00:49:15,640 PARTICULARLY BUILDING LARGE 1283 00:49:15,640 --> 00:49:17,040 STRUCTURES BUT MOVING NOW INTO 1284 00:49:17,040 --> 00:49:19,040 SOFTER AREAS WITH LOTS OF 1285 00:49:19,040 --> 00:49:20,880 UNCERTAINTIES WHERE OBVIOUSLY 1286 00:49:20,880 --> 00:49:22,520 THE LEVEL OF DIFFICULTY IS MUCH 1287 00:49:22,520 --> 00:49:24,960 HIGHER AND QUITE DIFFICULT TO 1288 00:49:24,960 --> 00:49:26,880 HAVE ANALYTICAL MODELS MUCH LESS 1289 00:49:26,880 --> 00:49:28,200 STATISTICAL TO PREDICT BEHAVIOR 1290 00:49:28,200 --> 00:49:35,200 BUT THIS WOULD IMPACT EARTH AND 1291 00:49:35,200 --> 00:49:36,160 ENVIRONMENTAL SYSTEMS, 1292 00:49:36,160 --> 00:49:38,360 BIOMEDICAL AND SPACE, HOT 1293 00:49:38,360 --> 00:49:39,120 TOPICS, OPPORTUNITIES FOR 1294 00:49:39,120 --> 00:49:40,320 CROSS-FERTILIZATION BETWEEN THE 1295 00:49:40,320 --> 00:49:41,360 THREE AREAS, THERE WILL BE 1296 00:49:41,360 --> 00:49:43,160 MULTIPLE REPORTS THAT COME FROM 1297 00:49:43,160 --> 00:49:44,280 THESE WORKSHOPS. 1298 00:49:44,280 --> 00:49:46,760 IF YOU'RE INTERESTED IN ENGAGING 1299 00:49:46,760 --> 00:49:49,080 IN THIS, SEE THE WEBSITE AND 1300 00:49:49,080 --> 00:49:49,960 PLEASE CONTACT GRACE. 1301 00:49:49,960 --> 00:49:52,200 WE'RE HOPING THERE WILL BE SOME 1302 00:49:52,200 --> 00:49:53,480 NEW OPPORTUNITIES THAT COME OUT 1303 00:49:53,480 --> 00:49:54,200 AS A RESULT. 1304 00:49:54,200 --> 00:49:56,360 NOT JUST AS A RESULT OF THIS BUT 1305 00:49:56,360 --> 00:49:58,760 THROUGHOUT THE COURSE OF THIS 1306 00:49:58,760 --> 00:50:02,200 PROCESS WE'RE HOPING TO BE ABLE 1307 00:50:02,200 --> 00:50:06,640 TO ADVANCE NEW APPROACHES IN 1308 00:50:06,640 --> 00:50:08,480 DIGITAL TWIN TECHNOLOGIES. 1309 00:50:08,480 --> 00:50:10,040 SO I'D LIKE TO TURN TOWARDS 1310 00:50:10,040 --> 00:50:11,520 UPDATES IN THE INTRAMURAL 1311 00:50:11,520 --> 00:50:12,440 PROGRAM. 1312 00:50:12,440 --> 00:50:15,880 AND SOME OF OUR HIRING 1313 00:50:15,880 --> 00:50:16,200 HIGHLIGHTS. 1314 00:50:16,200 --> 00:50:19,520 ONE IMPORTANT AND EXCITING ONE 1315 00:50:19,520 --> 00:50:21,200 IS KAITLIN SADTLER'S RECOGNITION 1316 00:50:21,200 --> 00:50:23,680 WITH AN HONORARY DOCTORATE FROM 1317 00:50:23,680 --> 00:50:27,040 UNIVERSITY OF MARYLAND, 1318 00:50:27,040 --> 00:50:28,400 BALTIMORE COUNTY, UMBC. 1319 00:50:28,400 --> 00:50:31,480 AND I JUST THINK THE BEST WAY TO 1320 00:50:31,480 --> 00:50:38,480 SHOW YOU ABOUT THIS DOCTORATE 1321 00:50:38,480 --> 00:50:40,880 IS TO GIVE YOU A CLIP OF THE 1322 00:50:40,880 --> 00:50:42,600 PRESIDENT OF UMBC GIVING THE 1323 00:50:42,600 --> 00:50:42,800 AWARD. 1324 00:50:42,800 --> 00:50:43,880 >> BY VIRTUE OF THE AUTHORITY 1325 00:50:43,880 --> 00:50:45,920 VESTED IN ME BY THE STATE OF 1326 00:50:45,920 --> 00:50:48,000 MARYLAND, AND GIVEN TO ME BY THE 1327 00:50:48,000 --> 00:50:49,680 CHANCELLOR OF THE UNIVERSITY 1328 00:50:49,680 --> 00:50:51,000 SYSTEM OF MARYLAND, AND UPON THE 1329 00:50:51,000 --> 00:50:53,360 UNANIMOUS VOTE OF THE BOARD OF 1330 00:50:53,360 --> 00:50:56,160 REGENTS, I CONFER UPON YOU THE 1331 00:50:56,160 --> 00:50:57,280 DEGREE OF DOCTORAL SCIENCE 1332 00:50:57,280 --> 00:51:01,080 TOGETHER WITH ALL THE RIGHTS AND 1333 00:51:01,080 --> 00:51:02,040 PRIVILEGES THEREUNTO PERTAINING. 1334 00:51:02,040 --> 00:51:06,080 NOW PLEASE JOIN ME IN WELCOMING 1335 00:51:06,080 --> 00:51:08,840 DR. KAITLIN SADTLER TO PRESENT 1336 00:51:08,840 --> 00:51:17,560 THE SECOND COMMENCEMENT ADDRESS. 1337 00:51:17,560 --> 00:51:17,840 [APPLAUSE] 1338 00:51:17,840 --> 00:51:20,040 >> I'M A MILLENNIAL, THIS IS 1339 00:51:20,040 --> 00:51:22,080 COMING FROM MY PHONE. 1340 00:51:22,080 --> 00:51:24,400 SO, FIRST OFF, THANK YOU SO 1341 00:51:24,400 --> 00:51:27,120 MUCH, THANK YOU SO MUCH TO THE 1342 00:51:27,120 --> 00:51:28,080 UMBC COMMUNITY FOR INVITING ME 1343 00:51:28,080 --> 00:51:29,080 TO BE HERE TODAY. 1344 00:51:29,080 --> 00:51:32,120 I ALSO WANT TO THANK DR. 1345 00:51:32,120 --> 00:51:32,360 CORBETT. 1346 00:51:32,360 --> 00:51:33,880 I BELIEVE SHE'S A BIG REASON I'M 1347 00:51:33,880 --> 00:51:36,000 STANDING ON THE STAGE TODAY. 1348 00:51:36,000 --> 00:51:41,560 SHE SENT A SHORT E-MAIL TO DR. 1349 00:51:41,560 --> 00:51:43,200 RIBOWSKI SAYING THERE'S ANOTHER 1350 00:51:43,200 --> 00:51:46,080 UMBC ALUM DOING RESEARCH AT THE 1351 00:51:46,080 --> 00:51:48,440 NIH, A HUGE CATALYST, THANK YOU 1352 00:51:48,440 --> 00:51:51,720 SO MUCH, DR. CORBETT. 1353 00:51:51,720 --> 00:51:52,880 [APPLAUSE] 1354 00:51:52,880 --> 00:51:58,160 >> WE WANT TO CONGRATULATE THE 1355 00:51:58,160 --> 00:52:00,680 CHIEF OF OUR IMMUNOENGINEERING 1356 00:52:00,680 --> 00:52:01,480 SECTION FOR THOSE CONTINUING 1357 00:52:01,480 --> 00:52:02,920 COUNCIL MEMBERS, YOU'VE SEEN ME 1358 00:52:02,920 --> 00:52:06,080 PRESENT HER RESEARCH, I THINK IN 1359 00:52:06,080 --> 00:52:07,360 VIRTUALLY EVERY COUNCIL. 1360 00:52:07,360 --> 00:52:09,240 SHE LED THE KEY SEROLOGY SURVEY 1361 00:52:09,240 --> 00:52:10,600 THAT TIPPED PEOPLE OFF FOR THE 1362 00:52:10,600 --> 00:52:12,600 FIRST TIME THAT THE NUMBER OF 1363 00:52:12,600 --> 00:52:15,560 COVID CASES IN THE COUNTRY WAS 1364 00:52:15,560 --> 00:52:17,000 MAYBE SEVEN OR EIGHT TIMES THE 1365 00:52:17,000 --> 00:52:18,840 NUMBER OF COVID CASES THAT THE 1366 00:52:18,840 --> 00:52:22,280 CDC HAD BEEN PROJECTING THAT WE 1367 00:52:22,280 --> 00:52:24,680 WERE HAVING, VERY IMPACTFUL AND 1368 00:52:24,680 --> 00:52:25,320 BEAUTIFUL RESULTS, SHE CONTINUES 1369 00:52:25,320 --> 00:52:30,320 TO DO WORK IN THIS AREA. 1370 00:52:30,320 --> 00:52:32,760 SO THIS IS SAD NEWS FOR US. 1371 00:52:32,760 --> 00:52:39,000 AND YOU MAY HAVE HEARD THIS, ONE 1372 00:52:39,000 --> 00:52:43,120 OF OUR SUPERSTAR SENIOR 1373 00:52:43,120 --> 00:52:47,280 INVESTIGATORS JUST LEFT NIBIB, 1374 00:52:47,280 --> 00:52:49,880 HARI SHROFF IS JOINING JANELIA 1375 00:52:49,880 --> 00:52:50,240 FARMS. 1376 00:52:50,240 --> 00:52:53,280 SOME OF YOU HAVE HEARD HIS TALKS 1377 00:52:53,280 --> 00:52:57,080 IF YOU'RE IN OPTICS AND 1378 00:52:57,080 --> 00:52:59,160 PHOTONICS, A SUPERSTAR AND 1379 00:52:59,160 --> 00:53:00,600 WIZARD WITH OPTICAL MICROSCOPY, 1380 00:53:00,600 --> 00:53:07,840 INVENTED A SUCCESSION OF REALLY 1381 00:53:07,840 --> 00:53:09,760 SPECTACULAR APPROACHES, ISPIN, 1382 00:53:09,760 --> 00:53:15,040 MSIM, BUT THE BOTTOM LINE 1383 00:53:15,040 --> 00:53:19,640 SUPER-RESOLUTION, HIGH-PEAKED, 1384 00:53:19,640 --> 00:53:22,120 LOW PHOTOTOXICITY 4D MICROSCOPY, 1385 00:53:22,120 --> 00:53:24,640 ADVANCED AN NIH WIDE AIM 1386 00:53:24,640 --> 00:53:27,480 FACILITY IN NIBIB THAT WILL STAY 1387 00:53:27,480 --> 00:53:28,800 HERE, HARI WILL TAKE HIS 1388 00:53:28,800 --> 00:53:30,320 RESEARCH PROGRAM AND MOVE TO 1389 00:53:30,320 --> 00:53:34,920 JANELIA BUT THE LEGACY OF HARI'S 1390 00:53:34,920 --> 00:53:36,320 WORK WILL STAY AND HE WILL 1391 00:53:36,320 --> 00:53:38,080 MAINTAIN TIES WITH NIBIB AND BE 1392 00:53:38,080 --> 00:53:40,320 ABLE TO REMAIN APPOINTED AND 1393 00:53:40,320 --> 00:53:41,360 CONTINUE TO COLLABORATE WITH 1394 00:53:41,360 --> 00:53:42,560 INVESTIGATORS HERE AFTER HIS 1395 00:53:42,560 --> 00:53:43,120 MOVE. 1396 00:53:43,120 --> 00:53:46,040 HE HAD A REALLY SPECTACULAR 1397 00:53:46,040 --> 00:53:48,360 OPPORTUNITY AT JANELIA AND WE 1398 00:53:48,360 --> 00:53:49,760 CONGRATULATE HARI ON THAT. 1399 00:53:49,760 --> 00:53:55,960 AND WE CONTINUE TO PUSH FORWARD 1400 00:53:55,960 --> 00:53:57,200 TO EXPAND DESPITE HARI'S LOSS 1401 00:53:57,200 --> 00:53:58,640 OUR INTRAMURAL PROGRAM AND ITS 1402 00:53:58,640 --> 00:53:58,960 CAPABILITIES. 1403 00:53:58,960 --> 00:54:02,560 ONE OF THOSE IS THE IDEAS LAB. 1404 00:54:02,560 --> 00:54:06,280 AND THIS IS NOW OFFICIALLY FULLY 1405 00:54:06,280 --> 00:54:09,000 EMBEDDED IN NIBIB'S INTRAMURAL 1406 00:54:09,000 --> 00:54:09,320 PROGRAM. 1407 00:54:09,320 --> 00:54:17,160 TOM POHIDA LEADS THIS PROGRAM 1408 00:54:17,160 --> 00:54:20,680 WITH EIGHT STAFF ENGINEERS. 1409 00:54:20,680 --> 00:54:22,000 IT'S INSTRUMENTATION DEVELOPMENT 1410 00:54:22,000 --> 00:54:23,200 AND SOLUTIONS, THAT'S THE ORIGIN 1411 00:54:23,200 --> 00:54:27,280 OF THE ACRONYM. 1412 00:54:27,280 --> 00:54:29,560 MANY ACTIVE PROJECTS AND 1413 00:54:29,560 --> 00:54:32,160 COLLABORATIONS ACROSS MOST NIH 1414 00:54:32,160 --> 00:54:34,360 INSTITUTES, PROVIDE ENGINEERS 1415 00:54:34,360 --> 00:54:34,920 AND COMPUTATION, PROTOTYPING 1416 00:54:34,920 --> 00:54:36,000 EXPERTISE, THIS IS THE 1417 00:54:36,000 --> 00:54:38,960 EQUIVALENT OF HAVING OUR OWN 1418 00:54:38,960 --> 00:54:40,040 SCHOOL OF ENGINEERING 1419 00:54:40,040 --> 00:54:44,480 CAPABILITIES, AND IT'S A REAL 1420 00:54:44,480 --> 00:54:46,480 FOCAL POINT FOR TRAINING, FOR 1421 00:54:46,480 --> 00:54:47,840 STUDENTS WHO COME PARTICULARLY 1422 00:54:47,840 --> 00:54:51,000 IN THE SUMMER, AND WILL BE AN 1423 00:54:51,000 --> 00:54:51,760 INCREDIBLY IMPORTANT 1424 00:54:51,760 --> 00:54:57,720 FOUNDATIONAL PIECE WHEN WE 1425 00:54:57,720 --> 00:54:59,200 ESTABLISH OUR BIOMEDICAL 1426 00:54:59,200 --> 00:55:02,840 ENGINEERING AND TECHNOLOGY 1427 00:55:02,840 --> 00:55:03,080 CENTER. 1428 00:55:03,080 --> 00:55:03,960 AGAIN PUSHING TO INCREASE 1429 00:55:03,960 --> 00:55:06,800 VISIBILITY AN IMPACT OF OUR 1430 00:55:06,800 --> 00:55:07,480 INTRAMURAL RESEARCH PROGRAM, 1431 00:55:07,480 --> 00:55:09,400 WE'VE HAD POSTED ON OUR WEBSITE 1432 00:55:09,400 --> 00:55:14,240 WHICH IS REQUIRED WHEN WE DO A 1433 00:55:14,240 --> 00:55:15,880 REORGANIZATIONAL STRUCTURE THE 1434 00:55:15,880 --> 00:55:18,800 NEW APPEARANCE OF OUR INTRAMURAL 1435 00:55:18,800 --> 00:55:20,880 RESEARCH PROGRAMS INCLUDING BETA 1436 00:55:20,880 --> 00:55:24,000 CENTER AND THIS IS AN NIH-WIDE 1437 00:55:24,000 --> 00:55:26,680 CENTER THAT WE BELIEVE WILL BE A 1438 00:55:26,680 --> 00:55:29,560 NEW MODEL FOR TECHNOLOGY DRIVEN 1439 00:55:29,560 --> 00:55:30,200 TRANSLATIONAL RESEARCH AN 1440 00:55:30,200 --> 00:55:31,480 CLINICAL TRANSLATION. 1441 00:55:31,480 --> 00:55:34,560 AND WE THINK WITHIN NIH WE CAN 1442 00:55:34,560 --> 00:55:36,520 HELP ACCELERATE THE DEVELOPMENT 1443 00:55:36,520 --> 00:55:38,400 VALIDATION AND DISSEMINATION OF 1444 00:55:38,400 --> 00:55:40,360 TECHNOLOGIES AND PARTNERSHIP 1445 00:55:40,360 --> 00:55:42,360 WITH THE EXTRAMURAL COMMUNITY 1446 00:55:42,360 --> 00:55:43,520 BOTH WITH TECHNOLOGIES THAT MAY 1447 00:55:43,520 --> 00:55:46,160 BE DEVELOPED FROM THE EXTRAMURAL 1448 00:55:46,160 --> 00:55:48,240 COMMUNITY BUT ALSO BE AN 1449 00:55:48,240 --> 00:55:51,240 OPPORTUNITY TO LEAD THE 1450 00:55:51,240 --> 00:55:52,480 EXPANSION OF DIVERSITY, EQUITY, 1451 00:55:52,480 --> 00:55:56,160 AND INCLUSION BY ATTRACTING 1452 00:55:56,160 --> 00:55:58,040 TRAINEES AND POTENTIALLY NEW 1453 00:55:58,040 --> 00:56:02,080 FTEs TO COME INTO THE NIBIB 1454 00:56:02,080 --> 00:56:04,880 AND NIH INTRAMURAL RESEARCH 1455 00:56:04,880 --> 00:56:05,120 PROGRAM. 1456 00:56:05,120 --> 00:56:08,000 THE DIRECTOR OF BETA WILL BE 1457 00:56:08,000 --> 00:56:11,080 ALSO NIBIB'S ASSOCIATE DIRECTOR 1458 00:56:11,080 --> 00:56:13,360 FOR DIVERSITY, EQUITY, 1459 00:56:13,360 --> 00:56:15,080 INCLUSION, AND ACCESSIBILITY, 1460 00:56:15,080 --> 00:56:18,760 AND JUST TO -- I THINK EVERYONE 1461 00:56:18,760 --> 00:56:20,640 LIKES WORD CHARTS BUT I HOPE I 1462 00:56:20,640 --> 00:56:23,480 DON'T CONFUSE YOU WITH THIS ONE, 1463 00:56:23,480 --> 00:56:25,360 TO ILLUSTRATE THAT POINT. 1464 00:56:25,360 --> 00:56:28,880 THE BETA CENTER DIRECTOR WHO IS 1465 00:56:28,880 --> 00:56:32,440 ALSO ASSOCIATE DIRECTOR FOR 1466 00:56:32,440 --> 00:56:35,880 DEIA, IS A MAJOR RECRUIT THAT'S 1467 00:56:35,880 --> 00:56:37,400 IN PROGRESS AND ALMOST -- WE'RE 1468 00:56:37,400 --> 00:56:38,080 ALMOST THERE. 1469 00:56:38,080 --> 00:56:40,520 BUT THAT'S ABOUT ALL I CAN SAY 1470 00:56:40,520 --> 00:56:44,880 ABOUT IT RIGHT NOW. 1471 00:56:44,880 --> 00:56:46,200 IT'S IN PROGRESS. 1472 00:56:46,200 --> 00:56:51,600 WE ALSO HAVE A SCIENTIFIC 1473 00:56:51,600 --> 00:56:55,600 DIVERSITY OFFICER, ALSO A MAJOR 1474 00:56:55,600 --> 00:56:57,200 RECRUIT IN PROCESS JUST ABOUT 1475 00:56:57,200 --> 00:56:58,720 WRAPPED UP, I CAN'T ANNOUNCE YET 1476 00:56:58,720 --> 00:57:00,400 BUT HOPEFULLY BY NEXT COUNCIL 1477 00:57:00,400 --> 00:57:03,320 MEETING OR AT SOME POINT IN 1478 00:57:03,320 --> 00:57:05,440 BETWEEN WE'LL BE ABLE TO 1479 00:57:05,440 --> 00:57:07,280 ANNOUNCE BOTH. 1480 00:57:07,280 --> 00:57:10,080 WE ALSO HAVE OUR EXTRAMURAL 1481 00:57:10,080 --> 00:57:10,720 SCIENCE PROGRAM DIRECTOR, DAVE 1482 00:57:10,720 --> 00:57:12,840 GEORGE HAS BEEN THE ACTING 1483 00:57:12,840 --> 00:57:14,920 DIRECTOR. 1484 00:57:14,920 --> 00:57:15,920 THIS RECRUITMENT IS IN PROGRESS. 1485 00:57:15,920 --> 00:57:19,440 AND WE NOW HAVE A NEW POSTING 1486 00:57:19,440 --> 00:57:22,480 FOR A DIVISION DIRECTOR WHO IS 1487 00:57:22,480 --> 00:57:24,000 IN APPLIED SCIENCE AND 1488 00:57:24,000 --> 00:57:26,720 TECHNOLOGY WHICH IS OUR 1489 00:57:26,720 --> 00:57:27,840 ESSENTIALLY HOUSING ALL 1490 00:57:27,840 --> 00:57:28,280 BIOIMAGING ACTIVITIES. 1491 00:57:28,280 --> 00:57:30,640 SO I WANTED TO BRING THIS TO 1492 00:57:30,640 --> 00:57:32,480 YOUR ATTENTION. 1493 00:57:32,480 --> 00:57:34,560 THIS IS POSTING OF AN OPENING, 1494 00:57:34,560 --> 00:57:35,880 AND AN OPPORTUNITY POTENTIALLY 1495 00:57:35,880 --> 00:57:37,040 FOR COLLEAGUES OF YOURS. 1496 00:57:37,040 --> 00:57:41,600 IT WILL BE ON USA JOBS AS WELL 1497 00:57:41,600 --> 00:57:43,680 AS NIBIB'S WEBSITE, OPENING ON 1498 00:57:43,680 --> 00:57:44,920 THE 21st OF SEPTEMBER, CLOSE 1499 00:57:44,920 --> 00:57:45,480 ON THE 30th. 1500 00:57:45,480 --> 00:57:48,440 SO THIS IS A DIVISION DIRECTOR 1501 00:57:48,440 --> 00:57:49,760 FOR THE ENTIRE DIVISION OF 1502 00:57:49,760 --> 00:57:50,840 APPLIED SCIENCE AND TECHNOLOGY 1503 00:57:50,840 --> 00:57:58,920 WHICH, AGAIN, IS OUR IMAGING 1504 00:57:58,920 --> 00:57:59,560 TECHNOLOGY PROGRAM. 1505 00:57:59,560 --> 00:58:02,280 I'D LIKE TO CONCLUDE WITH 1506 00:58:02,280 --> 00:58:04,880 PANDEMIC RESPONSE AND UPDATES ON 1507 00:58:04,880 --> 00:58:06,080 MIDRC AND RADx. 1508 00:58:06,080 --> 00:58:08,600 JILL WILL HELP ME WITH THOSE AS 1509 00:58:08,600 --> 00:58:08,800 WELL. 1510 00:58:08,800 --> 00:58:11,280 AS I MENTIONED, OUR BIG PANDEMIC 1511 00:58:11,280 --> 00:58:13,760 RESPONSE FROM 2020 HAS BEEN IN 1512 00:58:13,760 --> 00:58:16,560 THREE MAJOR AREAS, IMAGING AND 1513 00:58:16,560 --> 00:58:18,120 A.I., IN VITRO DIAGNOSTICS AND 1514 00:58:18,120 --> 00:58:21,600 DIGITAL HEALTH. 1515 00:58:21,600 --> 00:58:24,280 IN MIDRC THE PROGRESS IS 1516 00:58:24,280 --> 00:58:27,520 NON-LINEAR, A TRIBUTE TO OUR 1517 00:58:27,520 --> 00:58:29,520 P.I. FOR THIS PROGRAM, MARYELLEN 1518 00:58:29,520 --> 00:58:29,720 GIGER. 1519 00:58:29,720 --> 00:58:32,120 WE ANNOUNCED THAT SHE WAS 1520 00:58:32,120 --> 00:58:34,720 ROTATING OFF COUNCIL SO A WAY TO 1521 00:58:34,720 --> 00:58:36,040 THANK YOU FOR YOUR AMAZING 1522 00:58:36,040 --> 00:58:38,280 CONTRIBUTIONS AGAIN AS WE DID 1523 00:58:38,280 --> 00:58:42,200 LAST TIME, AND LEAVING A LEGACY 1524 00:58:42,200 --> 00:58:46,040 OF GROWTH WITH THIS PROGRAM. 1525 00:58:46,040 --> 00:58:48,120 THE OPEN COMMONS RELEASED 10 1526 00:58:48,120 --> 00:58:49,920 TERABYTES OF DATA, 62,000 1527 00:58:49,920 --> 00:58:51,680 IMAGING STUDIES, AND WHAT'S 1528 00:58:51,680 --> 00:58:54,280 SPECTACULAR THERE ARE 90,000 1529 00:58:54,280 --> 00:58:56,560 IMAGING STUDIES STILL GOING, 1530 00:58:56,560 --> 00:58:58,280 UNDERGOING MIDRC DATA QUALITY 1531 00:58:58,280 --> 00:58:58,960 AND HARMONIZATION. 1532 00:58:58,960 --> 00:59:02,960 AND THERE ARE NOW MORE THAN 230 1533 00:59:02,960 --> 00:59:05,880 USERS FROM MORE THAN 160 1534 00:59:05,880 --> 00:59:07,920 INSTITUTIONS, THERE ARE ABOUT 30 1535 00:59:07,920 --> 00:59:10,160 PUBLICATIONS THAT HAVE COME OUT. 1536 00:59:10,160 --> 00:59:12,960 AND AS WE'VE ALWAYS POINTED OUT 1537 00:59:12,960 --> 00:59:15,320 IN UPDATES HERE, THERE'S A 1538 00:59:15,320 --> 00:59:18,480 SEQUESTERED DATA COMMONS, 5,000 1539 00:59:18,480 --> 00:59:19,440 IMAGING STUDIES THAT ARE 1540 00:59:19,440 --> 00:59:22,520 SEQUESTERED TO REALLY HAVE REAL 1541 00:59:22,520 --> 00:59:24,400 WORLD ASSESSMENT OF ALGORITHMIC 1542 00:59:24,400 --> 00:59:24,680 PERFORMANCE. 1543 00:59:24,680 --> 00:59:26,680 AND ONE OF THE KIND OF HOLY 1544 00:59:26,680 --> 00:59:30,280 GRAILS OF OUR FIELD, A MAJOR 1545 00:59:30,280 --> 00:59:32,640 BARRIER, HAS NOW BEEN OVERCOME. 1546 00:59:32,640 --> 00:59:35,960 WE ALL SIT AT THE NIH AND SEE 1547 00:59:35,960 --> 00:59:39,040 THESE AMAZING DATABASES. 1548 00:59:39,040 --> 00:59:45,600 SO NHLBI HAS BIODATA CATALYST, 1549 00:59:45,600 --> 00:59:49,240 CLINICAL DATABASE, PET AL 1550 00:59:49,240 --> 00:59:50,960 DATABASE, AT NCATS, MOST OF THE 1551 00:59:50,960 --> 00:59:53,160 DATABASES AT THE NIH ARE 1552 00:59:53,160 --> 00:59:56,800 CLINICAL DATA, ELECTRONIC HEALTH 1553 00:59:56,800 --> 00:59:58,040 RECORDS, PATHOLOGY DATA, 1554 00:59:58,040 --> 00:59:58,920 GENOMICS DATA, METABOLOMICS, 1555 00:59:58,920 --> 01:00:01,640 EVEN MOBILE HEALTH DATA. 1556 01:00:01,640 --> 01:00:04,120 ALL OF US HAVE AN EXTRAORDINARY 1557 01:00:04,120 --> 01:00:09,360 AMOUNT OF MOBILE HEALTH DATA IN 1558 01:00:09,360 --> 01:00:10,600 THEIR DATABASE, VERY FEW ARE 1559 01:00:10,600 --> 01:00:12,240 USING OR CONNECTING TO IMAGING 1560 01:00:12,240 --> 01:00:14,480 DATA AN OTHER CLINICAL 1561 01:00:14,480 --> 01:00:14,760 DATABASES. 1562 01:00:14,760 --> 01:00:18,040 FOR THE FIRST TIME MIDRC HAS 1563 01:00:18,040 --> 01:00:21,640 ACHIEVED THE LINKAGE WORKING IN 1564 01:00:21,640 --> 01:00:26,720 PARTNERSHIP WITH NHLBI AND 1565 01:00:26,720 --> 01:00:29,840 NCATS, BETWEEN THE IMAGING 1566 01:00:29,840 --> 01:00:31,000 DATABASES, INTEROPERABILITY WITH 1567 01:00:31,000 --> 01:00:32,640 OTHER DATABASES, THOUSANDS OF 1568 01:00:32,640 --> 01:00:35,080 SUBJECTS OVERLAP WITHIN ALL OF 1569 01:00:35,080 --> 01:00:36,400 THESE DATABASES. 1570 01:00:36,400 --> 01:00:37,680 SO, REALLY FOR THE FIRST TIME 1571 01:00:37,680 --> 01:00:40,080 SOME OF THE TECHNICAL CHALLENGES 1572 01:00:40,080 --> 01:00:41,400 HAVE BEEN ADDRESSED, THE 1573 01:00:41,400 --> 01:00:44,240 OPPORTUNITY FOR THE FUTURE IN 1574 01:00:44,240 --> 01:00:46,520 MULTIPLE DATABASE LINKAGE REALLY 1575 01:00:46,520 --> 01:00:48,080 HAS BEEN CONQUERED. 1576 01:00:48,080 --> 01:00:49,920 THIS IS A WONDERFUL 1577 01:00:49,920 --> 01:00:51,240 ACCOMPLISHMENT OF THIS PROGRAM, 1578 01:00:51,240 --> 01:00:53,200 AND IN THE PROCESS IT'S CREATED 1579 01:00:53,200 --> 01:00:57,000 A VISIBILITY FOR THE IMAGING 1580 01:00:57,000 --> 01:00:59,120 COMMUNITY AND IMAGING DATABASES, 1581 01:00:59,120 --> 01:01:01,120 AS BEING EQUIVALENT AND QUITE 1582 01:01:01,120 --> 01:01:03,320 POWERFUL TO ALL OF THE CLINICAL 1583 01:01:03,320 --> 01:01:04,520 DATABASE ACCUMULATION THAT'S 1584 01:01:04,520 --> 01:01:08,360 GOING ON IN NIH STUDIES. 1585 01:01:08,360 --> 01:01:12,320 IN TERMS OF RADx TECH, JUST A 1586 01:01:12,320 --> 01:01:15,480 QUICK UPDATE ON NUMBERS. 1587 01:01:15,480 --> 01:01:18,960 THROUGH JUNE OF 2022, THE 1588 01:01:18,960 --> 01:01:21,280 CUMULATIVE TEST CAPACITY 1589 01:01:21,280 --> 01:01:22,360 INCREASE HAS BEEN ALMOST 4 1590 01:01:22,360 --> 01:01:23,240 BILLION TESTS. 1591 01:01:23,240 --> 01:01:26,640 SO, SINCE WE MET LAST TIME, IN 1592 01:01:26,640 --> 01:01:31,960 MAY, WHERE WE WERE UPDATING 1593 01:01:31,960 --> 01:01:33,600 THROUGH ROUGHLY FEBRUARY OR 1594 01:01:33,600 --> 01:01:36,480 MARCH I THINK AT THE TIME, WE 1595 01:01:36,480 --> 01:01:37,680 WERE AT ABOUT 2 BILLION IN TERMS 1596 01:01:37,680 --> 01:01:40,000 OF INCREASE IN TESTING CAPACITY. 1597 01:01:40,000 --> 01:01:42,960 THAT'S NOW DOUBLED AGAIN. 1598 01:01:42,960 --> 01:01:44,120 THE DOMINANT CONTRIBUTORS TO 1599 01:01:44,120 --> 01:01:45,880 THOSE ARE OVER THE COUNTER 1600 01:01:45,880 --> 01:01:48,600 TESTS, EVERYONE IS USING THOSE 1601 01:01:48,600 --> 01:01:49,560 AT HOME, AND THERE STILL 1602 01:01:49,560 --> 01:01:51,320 HUNDREDS OF MILLIONS OF TEST AND 1603 01:01:51,320 --> 01:01:55,960 TEST PRODUCTS THAT ARE BEING 1604 01:01:55,960 --> 01:01:56,720 RELEASED, PRODUCED AND 1605 01:01:56,720 --> 01:01:59,080 PURCHASED, BY INDIVIDUALS ALL 1606 01:01:59,080 --> 01:02:01,480 AROUND THE COUNTRY IN ORDER TO 1607 01:02:01,480 --> 01:02:02,400 DO TESTING AT HOME. 1608 01:02:02,400 --> 01:02:06,480 THERE ARE A TOTAL OF 45 1609 01:02:06,480 --> 01:02:07,920 EMERGENCY USE AUTHORIZATIONS. 1610 01:02:07,920 --> 01:02:10,240 11 ARE FULLY OVER THE COUNTER. 1611 01:02:10,240 --> 01:02:13,800 ONE OF THEM IS A PCR APPROACH, 1612 01:02:13,800 --> 01:02:16,000 10 ARE ANTIGEN-BASED APPROACHES. 1613 01:02:16,000 --> 01:02:17,920 THESE HAVE COME FROM A 1614 01:02:17,920 --> 01:02:22,800 COMBINATION OF INNOVATION FUNNEL 1615 01:02:22,800 --> 01:02:24,160 AND INDEPENDENT ASSESSMENT 1616 01:02:24,160 --> 01:02:24,640 PROGRAM. 1617 01:02:24,640 --> 01:02:27,680 THIS IS A HUGE IMPACT BUT WE'RE 1618 01:02:27,680 --> 01:02:28,000 NOT SATISFIED. 1619 01:02:28,000 --> 01:02:29,960 THERE'S STILL MORE TO DO. 1620 01:02:29,960 --> 01:02:34,120 AND I'M GOING TO CALL IN JILL, 1621 01:02:34,120 --> 01:02:35,320 MY COLLEAGUE JILL HEEMSKERK, TO 1622 01:02:35,320 --> 01:02:38,080 TELL US WHAT MORE THERE IS TO 1623 01:02:38,080 --> 01:02:39,280 TACKLE AND CHALLENGES THAT ARE 1624 01:02:39,280 --> 01:02:46,080 VERY, VERY IMPORTANT THAT WE 1625 01:02:46,080 --> 01:02:47,480 NEED TO TAKE ON. 1626 01:02:47,480 --> 01:02:49,240 >> I'M GOING TO TALK ABOUT THE 1627 01:02:49,240 --> 01:02:50,960 RADx EFFORTS TO PRODUCE HOME 1628 01:02:50,960 --> 01:02:54,080 TESTS ACCESSIBLE FOR USE BY 1629 01:02:54,080 --> 01:02:55,760 PEOPLE WITH DISABILITIES. 1630 01:02:55,760 --> 01:02:59,000 YOU'LL ALL REMEMBER EARLY THIS 1631 01:02:59,000 --> 01:03:00,800 YEAR THAT THE GOVERNMENT BEGAN 1632 01:03:00,800 --> 01:03:02,680 DISTRIBUTING FREE COVID TESTS TO 1633 01:03:02,680 --> 01:03:03,760 EVERYONE IN THE COUNTRY. 1634 01:03:03,760 --> 01:03:06,040 THIS WAS VERY GRATIFYING FOR 1635 01:03:06,040 --> 01:03:07,480 RADx, HAVING HELPED GROW THE 1636 01:03:07,480 --> 01:03:08,920 TESTING CAPACITY TO THE POINT 1637 01:03:08,920 --> 01:03:11,080 WHERE EVERYONE HAD ACCESS TO 1638 01:03:11,080 --> 01:03:14,920 RAPID TESTING IN THEIR HOMES. 1639 01:03:14,920 --> 01:03:17,440 BUT THE ANNOUNCEMENT STIMULATED 1640 01:03:17,440 --> 01:03:19,240 AN URGENT LETTER WRITING 1641 01:03:19,240 --> 01:03:20,680 CAMPAIGN FOR DISABILITY 1642 01:03:20,680 --> 01:03:22,040 ADVOCATES, PARTICULARLY GROUPS 1643 01:03:22,040 --> 01:03:22,960 REPRESENTING THE BLIND. 1644 01:03:22,960 --> 01:03:24,640 POINTING OUT THAT THE TESTS WERE 1645 01:03:24,640 --> 01:03:26,600 NOT DESIGNED IN A WAY THEY COULD 1646 01:03:26,600 --> 01:03:29,480 BE USED INDEPENDENTLY BY PEOPLE 1647 01:03:29,480 --> 01:03:30,280 WITH DISABILITIES. 1648 01:03:30,280 --> 01:03:32,680 AND THIS WAS A BIG AHA MOMENT 1649 01:03:32,680 --> 01:03:35,440 FOR US REALIZING THAT IN OUR MAD 1650 01:03:35,440 --> 01:03:38,360 RUSH TO MAKE TESTS AVAILABLE AS 1651 01:03:38,360 --> 01:03:43,200 QUICKLY AS POSSIBLE, WE HAD BEEN 1652 01:03:43,200 --> 01:03:46,240 NEGLECTING ANY CONSIDERATION OF 1653 01:03:46,240 --> 01:03:48,680 PRINCIPLES OF UNIVERSAL DESIGN 1654 01:03:48,680 --> 01:03:49,480 AND ACCESSIBILITY AND WE'RE 1655 01:03:49,480 --> 01:03:54,680 EAGER TO CORRECT THIS OVERSIGHT 1656 01:03:54,680 --> 01:03:55,520 NOW. 1657 01:03:55,520 --> 01:04:00,000 SO, THESE LETTERS WENT TO NIH, 1658 01:04:00,000 --> 01:04:00,640 NIH DIRECTOR, TO THE DEPARTMENT 1659 01:04:00,640 --> 01:04:02,440 OF HEALTH AND HUMAN SERVICES, TO 1660 01:04:02,440 --> 01:04:05,080 THE WHITE HOUSE. 1661 01:04:05,080 --> 01:04:06,160 AND WE IMMEDIATELY STARTED 1662 01:04:06,160 --> 01:04:09,320 THINKING HOW MIGHT WE PROCEED. 1663 01:04:09,320 --> 01:04:10,960 AND WE FOUND THAT THERE'S 1664 01:04:10,960 --> 01:04:13,120 ACTUALLY VERY LITTLE GROUND WORK 1665 01:04:13,120 --> 01:04:14,560 ON WHAT ACCESSIBILITY EVEN MEANS 1666 01:04:14,560 --> 01:04:17,400 IN THE HOME TESTING SPACE. 1667 01:04:17,400 --> 01:04:21,440 AND SO WE CONVENED A LISTENING 1668 01:04:21,440 --> 01:04:24,720 SESSION IN MARCH WITH DISABILITY 1669 01:04:24,720 --> 01:04:26,600 ADVOCATES, AND THE SIX 1670 01:04:26,600 --> 01:04:28,880 GOVERNMENT AGENCIES THAT HAVE 1671 01:04:28,880 --> 01:04:30,200 ACCESSIBILITY IN THEIR MISSION. 1672 01:04:30,200 --> 01:04:33,680 AS WELL AS THE LEADERSHIP OF THE 1673 01:04:33,680 --> 01:04:36,560 CLINICAL CENTER AND DEPLOYMENT 1674 01:04:36,560 --> 01:04:39,800 CORE FOR RADx. 1675 01:04:39,800 --> 01:04:42,160 WE FORMED QUITE A GOOD GROUP AND 1676 01:04:42,160 --> 01:04:44,280 HAD AMAZING DISCUSSIONS, AND 1677 01:04:44,280 --> 01:04:46,880 THIS GROUP HAS STAYED TOGETHER 1678 01:04:46,880 --> 01:04:49,520 WITH US THROUGH THE SUBSEQUENT 1679 01:04:49,520 --> 01:04:50,600 MONTHS OF DESIGNING AND 1680 01:04:50,600 --> 01:04:51,160 IMPLEMENTING THE PROGRAM I'M 1681 01:04:51,160 --> 01:04:52,920 GOING TO TELL YOU ABOUT. 1682 01:04:52,920 --> 01:04:55,480 IN THIS MEETING, WE HAD THREE 1683 01:04:55,480 --> 01:04:56,800 BREAKOUT GROUPS, ONE FOR BLIND 1684 01:04:56,800 --> 01:04:58,800 AND LOW VISION, ONE FOR FINE 1685 01:04:58,800 --> 01:05:03,680 MOTOR IMPAIRMENT, ONE FOR OLDER 1686 01:05:03,680 --> 01:05:05,480 ADULTS CONSIDERING THINGS LIKE 1687 01:05:05,480 --> 01:05:08,880 NOT ONLY LOW VISION AND TREMOR 1688 01:05:08,880 --> 01:05:10,920 BUT COGNITIVE ISSUES AS WELL. 1689 01:05:10,920 --> 01:05:15,080 AND BRUCE, IF YOU GO TO THE NEXT 1690 01:05:15,080 --> 01:05:18,080 SLIDE, IT SHOWS SOME OF OUR 1691 01:05:18,080 --> 01:05:19,120 LEARNINGS FROM THEIR 1692 01:05:19,120 --> 01:05:19,440 DISCUSSIONS. 1693 01:05:19,440 --> 01:05:22,840 THEY WERE VERY, VERY REVEALING. 1694 01:05:22,840 --> 01:05:24,880 A LOT OF THE ISSUES CENTERED 1695 01:05:24,880 --> 01:05:28,640 AROUND THE PACKAGING OF THE 1696 01:05:28,640 --> 01:05:30,280 TESTS AND INSTRUCTIONS. 1697 01:05:30,280 --> 01:05:34,160 FOR EXAMPLE, THE GOVERNMENT WAS 1698 01:05:34,160 --> 01:05:35,280 SENDING OUT MULTIPLE DIFFERENT 1699 01:05:35,280 --> 01:05:36,600 KIND OF TESTS AND YOU DID NOT 1700 01:05:36,600 --> 01:05:39,440 KNOW WHAT YOU WERE GETTING TILL 1701 01:05:39,440 --> 01:05:40,880 YOU OPENED YOUR ENVELOPE. 1702 01:05:40,880 --> 01:05:44,280 BUT IF FOR PEOPLE WHO ARE BLIND, 1703 01:05:44,280 --> 01:05:46,480 GETTING A BOX IN THE MAIL IS NOT 1704 01:05:46,480 --> 01:05:48,120 VERY HELPFUL FOR THEM FINDING 1705 01:05:48,120 --> 01:05:50,720 THE INSTRUCTIONS BECAUSE THERE 1706 01:05:50,720 --> 01:05:51,960 ARE -- THERE'S NOTHING ON THE 1707 01:05:51,960 --> 01:05:53,680 BOX TO SCAN AND TELL THEM WHERE 1708 01:05:53,680 --> 01:05:55,920 TO GO TO FIND ACCESSIBLE 1709 01:05:55,920 --> 01:05:58,040 INSTRUCTIONS EVEN IF THEY WERE 1710 01:05:58,040 --> 01:05:58,320 AVAILABLE. 1711 01:05:58,320 --> 01:06:01,840 WE ALL KNOW INSTRUCTIONS ARE 1712 01:06:01,840 --> 01:06:03,640 COMPLICATED. 1713 01:06:03,640 --> 01:06:06,000 THE PRINT IS SMALL. 1714 01:06:06,000 --> 01:06:09,080 THERE'S OFTEN NOT SIMPLE 1715 01:06:09,080 --> 01:06:10,280 STEP-BY-STEP DIRECTIONS. 1716 01:06:10,280 --> 01:06:13,280 AND PARTICULARLY FOR OLDER 1717 01:06:13,280 --> 01:06:14,600 PEOPLE, FEW LANGUAGE OPTIONS, 1718 01:06:14,600 --> 01:06:17,880 AND OF COURSE NO BRAILLE AT ALL. 1719 01:06:17,880 --> 01:06:19,640 THE TEST PROCEDURE ITSELF WAS 1720 01:06:19,640 --> 01:06:23,920 ALSO -- IS ALSO REALLY 1721 01:06:23,920 --> 01:06:24,240 COMPLICATED. 1722 01:06:24,240 --> 01:06:26,120 TOO MANY STEPS IN THE WORKFLOW, 1723 01:06:26,120 --> 01:06:27,880 THE NEED TO COUNT DROPS OF 1724 01:06:27,880 --> 01:06:29,720 LIQUID AND SQUEEZE THOSE DROPS 1725 01:06:29,720 --> 01:06:31,480 INTO TINY HOLES ON THE DEVICE IS 1726 01:06:31,480 --> 01:06:34,000 DIFFICULT NOT ONLY FOR PEOPLE 1727 01:06:34,000 --> 01:06:36,920 WITH VISION IMPAIRMENT BUT ALSO 1728 01:06:36,920 --> 01:06:40,880 FOR PEOPLE WHO HAVE MOTOR 1729 01:06:40,880 --> 01:06:41,960 IMPAIRMENT, TREMOR, WEAKNESS. 1730 01:06:41,960 --> 01:06:45,800 LOTS OF SMALL PARTS THAT NEED TO 1731 01:06:45,800 --> 01:06:47,200 BE SNAPPED, UNSNAPPED TOGETHER, 1732 01:06:47,200 --> 01:06:49,480 AND INSTRUCTIONS THAT ARE VERY 1733 01:06:49,480 --> 01:06:52,600 HARD TO ACT ON IF YOU ARE -- IF 1734 01:06:52,600 --> 01:06:53,880 YOU DON'T HAVE VISION. 1735 01:06:53,880 --> 01:06:55,040 FOR EXAMPLE, THE INSTRUCTION TO 1736 01:06:55,040 --> 01:06:56,480 ADD DROPS TO THE HOLE ON THE TOP 1737 01:06:56,480 --> 01:06:58,120 WHEN YOU DON'T KNOW WHICH END OF 1738 01:06:58,120 --> 01:07:01,520 THE DEVICE IS UP WHEN THERE'S NO 1739 01:07:01,520 --> 01:07:03,080 INDICATOR OF THAT, OR THE 1740 01:07:03,080 --> 01:07:05,720 INSTRUCTION NOT TO TOUCH THINGS 1741 01:07:05,720 --> 01:07:10,680 LIKE THE SWAB OR THE WINDOWS ON 1742 01:07:10,680 --> 01:07:13,200 THE DEVICE ARE HUGE IMPEDIMENTS 1743 01:07:13,200 --> 01:07:15,000 FOR PEOPLE THAT NEED TO TOUCH TO 1744 01:07:15,000 --> 01:07:18,120 PROCEED THROUGH THE WORKFLOW. 1745 01:07:18,120 --> 01:07:22,160 CLEARLY FOR PEOPLE WHO ARE 1746 01:07:22,160 --> 01:07:22,960 VISION IMPAIRED, THE APPEARANCE 1747 01:07:22,960 --> 01:07:29,720 OF LINES ON THE STRIP IS NOT 1748 01:07:29,720 --> 01:07:30,240 INTERPRETABLE. 1749 01:07:30,240 --> 01:07:36,080 SOME TESTS HAVE READERS THAT 1750 01:07:36,080 --> 01:07:37,080 COMMUNICATE WITH SMARTPHONES 1751 01:07:37,080 --> 01:07:38,120 SMARTPHONES ARE NOT ACCESSIBLE 1752 01:07:38,120 --> 01:07:40,760 TO AS MUCH AS 40% OF THE 1753 01:07:40,760 --> 01:07:41,560 DISABILITY COMMUNITY. 1754 01:07:41,560 --> 01:07:44,920 THERE'S LOTS TO BE DONE, LOTS OF 1755 01:07:44,920 --> 01:07:45,720 CHALLENGES TO ADDRESS. 1756 01:07:45,720 --> 01:07:50,280 ON THE NEXT SLIDE, BRUCE, I'M 1757 01:07:50,280 --> 01:07:52,840 GOING TO TELL YOU ABOUT ONE ARM 1758 01:07:52,840 --> 01:07:57,080 OF OUR RESPONSE WHICH IS THE 1759 01:07:57,080 --> 01:07:57,800 FAST TRACK INITIATIVE. 1760 01:07:57,800 --> 01:07:59,560 IT WAS AN EFFORT TO THINK 1761 01:07:59,560 --> 01:08:01,920 THROUGH WHAT CAN WE DO QUICKLY 1762 01:08:01,920 --> 01:08:02,880 TO GET MODIFIED TESTS AVAILABLE 1763 01:08:02,880 --> 01:08:05,640 TO THE PUBLIC AS SOON AS 1764 01:08:05,640 --> 01:08:05,880 POSSIBLE. 1765 01:08:05,880 --> 01:08:07,880 BRUCE WILL TELL YOU NEXT ABOUT A 1766 01:08:07,880 --> 01:08:09,600 NEW INITIATIVE TO DEVELOP TESTS 1767 01:08:09,600 --> 01:08:10,920 FROM THE GROUND UP WITH 1768 01:08:10,920 --> 01:08:12,280 ACCESSIBILITY IN MIND BUT THIS 1769 01:08:12,280 --> 01:08:14,320 IDEA WAS TO JUST MAKE 1770 01:08:14,320 --> 01:08:15,680 IMPROVEMENTS AS QUICKLY AS WE 1771 01:08:15,680 --> 01:08:15,880 CAN. 1772 01:08:15,880 --> 01:08:18,480 AND SO THE IDEA HERE IS TO 1773 01:08:18,480 --> 01:08:21,000 MODIFY TESTS THAT ARE ALREADY ON 1774 01:08:21,000 --> 01:08:21,680 THE MARKET. 1775 01:08:21,680 --> 01:08:26,360 WE SET UP A PIPELINE FOR 1776 01:08:26,360 --> 01:08:29,960 EVALUATING THE ACCESSIBILITY OF 1777 01:08:29,960 --> 01:08:33,040 THE TESTS AND DESIGN IMPROVED 1778 01:08:33,040 --> 01:08:33,320 PROTOTYPES. 1779 01:08:33,320 --> 01:08:35,640 THIS PIPELINE IS SET UP WITH 1780 01:08:35,640 --> 01:08:38,280 CONTRACTORS WHO HAVE EXPERTISE 1781 01:08:38,280 --> 01:08:41,760 IN ACCESSIBILITY SPACE, AND IN 1782 01:08:41,760 --> 01:08:45,800 FACT WE HAVE DESIGNERS WHO ARE 1783 01:08:45,800 --> 01:08:48,440 BLIND, ENGINEERS WHO ARE BLIND 1784 01:08:48,440 --> 01:08:50,320 AND HAVE OTHER DISABILITIES TO 1785 01:08:50,320 --> 01:08:55,000 HELP THROUGH THIS PROCESS. 1786 01:08:55,000 --> 01:08:57,360 WE'RE GOING THROUGH NOW THE 1787 01:08:57,360 --> 01:09:00,640 DESIGN OF PROTOTYPES OF MODIFIED 1788 01:09:00,640 --> 01:09:03,680 TESTS IN COLLABORATION WITH THE 1789 01:09:03,680 --> 01:09:04,800 MANUFACTURERS, THOSE WILL GO FOR 1790 01:09:04,800 --> 01:09:09,680 AN EXPERT DESIGN REVIEW AND THE 1791 01:09:09,680 --> 01:09:12,200 EXPERT DESIGN REVIEWERS INCLUDE 1792 01:09:12,200 --> 01:09:13,880 END USERS FROM THE ADVOCACY 1793 01:09:13,880 --> 01:09:15,080 COMMUNITIES THAT WE PARTNERED 1794 01:09:15,080 --> 01:09:17,360 WITH EARLIER IN THE YEAR. 1795 01:09:17,360 --> 01:09:20,680 AND WE'RE ALSO WORKING OF COURSE 1796 01:09:20,680 --> 01:09:23,600 CLOSELY WITH THE FDA WHO WILL 1797 01:09:23,600 --> 01:09:26,080 HAVE TO APPROVE ANY 1798 01:09:26,080 --> 01:09:27,400 MODIFICATIONS TO THE TESTS 1799 01:09:27,400 --> 01:09:28,480 BEFORE MARKETING. 1800 01:09:28,480 --> 01:09:30,800 THEY ARE VERY POISED AND EAGER 1801 01:09:30,800 --> 01:09:33,080 TO HELP WITH THIS PROCESS. 1802 01:09:33,080 --> 01:09:37,480 WE HOPE THAT WE'LL BE GOING INTO 1803 01:09:37,480 --> 01:09:40,600 TEST PRODUCTION AS EARLY AS THIS 1804 01:09:40,600 --> 01:09:42,600 FALL OR WINTER. 1805 01:09:42,600 --> 01:09:44,320 AND WE'VE EXAMINED FOR 1806 01:09:44,320 --> 01:09:45,360 ACCESSIBILITY 25 DIFFERENT HOME 1807 01:09:45,360 --> 01:09:49,880 TESTS THAT ARE ON THE MARKET. 1808 01:09:49,880 --> 01:09:52,200 AND SELECTED 12 OF THOSE THAT 1809 01:09:52,200 --> 01:09:54,480 SEEM MOST AMENABLE TO 1810 01:09:54,480 --> 01:09:54,800 MODIFICATION. 1811 01:09:54,800 --> 01:09:56,880 THE OTHER TWO PARTS OF THIS 1812 01:09:56,880 --> 01:09:57,960 EFFORT ARE ON THE RIGHT HAND OF 1813 01:09:57,960 --> 01:10:00,680 THE SLIDE HERE, ONE IS THE 1814 01:10:00,680 --> 01:10:02,560 DEVELOPMENT OF AN INSTRUCTION 1815 01:10:02,560 --> 01:10:03,440 TEMPLATE. 1816 01:10:03,440 --> 01:10:06,280 WHEN THESE TESTS WENT THROUGH 1817 01:10:06,280 --> 01:10:08,120 THE ACCESSIBILITY EVALUATION, 1818 01:10:08,120 --> 01:10:09,440 ABOUT TWO-THIRDS OF THE CONCERNS 1819 01:10:09,440 --> 01:10:12,160 RAISED WERE AROUND THE 1820 01:10:12,160 --> 01:10:12,480 INSTRUCTIONS. 1821 01:10:12,480 --> 01:10:15,000 SO, WHAT WE'RE HOPING TO DO IS 1822 01:10:15,000 --> 01:10:16,680 DEVELOP A SORT OF TEMPLATE 1823 01:10:16,680 --> 01:10:20,200 APPROACH THAT WE CAN MAKE 1824 01:10:20,200 --> 01:10:22,360 AVAILABLE TO ANY MANUFACTURER, 1825 01:10:22,360 --> 01:10:23,680 SO THAT WHETHER PEOPLE ARE IN 1826 01:10:23,680 --> 01:10:25,680 THE PROGRAM OR NOT A COMPANY IS 1827 01:10:25,680 --> 01:10:27,360 IN THE PROGRAM OR NOT, THEY CAN 1828 01:10:27,360 --> 01:10:28,960 MODIFY THEIR INSTRUCTIONS TO BE 1829 01:10:28,960 --> 01:10:30,800 MORE ACCESSIBLE. 1830 01:10:30,800 --> 01:10:32,800 AND THIS WILL INCLUDE 1831 01:10:32,800 --> 01:10:37,800 SIMPLIFICATION, LARGER TYPE, 1832 01:10:37,800 --> 01:10:40,080 CLEAR LAYOUT, AND LINKAGE TO 1833 01:10:40,080 --> 01:10:42,080 WEB-BASED INSTRUCTION TO GO FROM 1834 01:10:42,080 --> 01:10:43,880 PAPER INSTRUCTIONS TO WEB-BASED 1835 01:10:43,880 --> 01:10:45,680 INSTRUCTIONS EASILY IF THEY NEED 1836 01:10:45,680 --> 01:10:46,280 TO. 1837 01:10:46,280 --> 01:10:48,800 AND OF COURSE THIS IS A CLOSE 1838 01:10:48,800 --> 01:10:51,240 PARTNERSHIP WITH THE FDA WHO HAS 1839 01:10:51,240 --> 01:10:54,480 BEEN VERY HELPFUL IN NOT ONLY 1840 01:10:54,480 --> 01:10:57,240 ADVISING US BUT PREPARING TO 1841 01:10:57,240 --> 01:11:00,560 ACCELERATE THE AUTHORIZATION OF 1842 01:11:00,560 --> 01:11:01,160 THE FINAL TEMPLATE. 1843 01:11:01,160 --> 01:11:03,360 AND WE'RE WORKING CLOSELY WITH 1844 01:11:03,360 --> 01:11:06,280 END USERS TO VALIDATE CHANGES 1845 01:11:06,280 --> 01:11:07,600 WE'RE PROPOSING ARE WELCOME. 1846 01:11:07,600 --> 01:11:09,160 THE OTHER THING THAT WE'RE DOING 1847 01:11:09,160 --> 01:11:13,600 IS A MORE GENERAL BEST PRACTICES 1848 01:11:13,600 --> 01:11:14,520 GUIDELINES FOR INDUSTRY. 1849 01:11:14,520 --> 01:11:19,480 WE'D LIKE TO MAKE THESE PUBLIC, 1850 01:11:19,480 --> 01:11:21,160 SO THAT MOVING FORWARD 1851 01:11:21,160 --> 01:11:22,080 MANUFACTURERS WILL HAVE A 1852 01:11:22,080 --> 01:11:23,800 RESOURCE TO LOOK AT TO TELL THEM 1853 01:11:23,800 --> 01:11:25,920 WHAT ARE PRINCIPLES THEY CAN 1854 01:11:25,920 --> 01:11:28,640 APPLY TO MAKE THEIR TESTS MORE 1855 01:11:28,640 --> 01:11:28,920 ACCESSIBLE. 1856 01:11:28,920 --> 01:11:32,680 AND WE'RE DESIGNING THIS TO BE 1857 01:11:32,680 --> 01:11:35,000 BROADLY APPLICABLE SO HOPEFULLY 1858 01:11:35,000 --> 01:11:36,520 IT WILL APPLY NOT JUST TO COVID 1859 01:11:36,520 --> 01:11:41,560 TESTS BUT LOTS OF HOME 1860 01:11:41,560 --> 01:11:44,320 DIAGNOSTIC AND HOME MEDICAL 1861 01:11:44,320 --> 01:11:44,680 DEVICES. 1862 01:11:44,680 --> 01:11:46,280 WE'RE PARTNERING WITH FDA AND 1863 01:11:46,280 --> 01:11:51,440 U.S. ACCESS BOARD, THE AGENCY 1864 01:11:51,440 --> 01:11:53,280 RESPONSIBLE FOR THE STANDARDS 1865 01:11:53,280 --> 01:11:56,720 RECOMMENDATIONS COMING UNDER THE 1866 01:11:56,720 --> 01:11:59,400 AMERICANS WITH DISABILITIES ACT. 1867 01:11:59,400 --> 01:12:03,280 SO ALL OF THIS IS TO GET 1868 01:12:03,280 --> 01:12:06,040 IMPROVEMENTS OUT AS QUICKLY AS 1869 01:12:06,040 --> 01:12:06,360 POSSIBLE. 1870 01:12:06,360 --> 01:12:07,880 NONE OF THIS WILL LIKELY BE 1871 01:12:07,880 --> 01:12:09,640 PERFECT BUT WE HOPE THAT WE WILL 1872 01:12:09,640 --> 01:12:13,120 MAKE SOME STRIDES IN THE 1873 01:12:13,120 --> 01:12:14,240 DIRECTION OF ACCESSIBILITY 1874 01:12:14,240 --> 01:12:16,280 RELATIVELY QUICKLY BY TAKING 1875 01:12:16,280 --> 01:12:16,960 THIS APPROACH. 1876 01:12:16,960 --> 01:12:18,680 BRUCE, I'LL TURN IT BACK TO YOU 1877 01:12:18,680 --> 01:12:27,000 TO TELL THEM ABOUT OUR NEW 1878 01:12:27,000 --> 01:12:27,480 INITIATIVES. 1879 01:12:27,480 --> 01:12:29,480 >> AS JILL SAID, WE'RE NOW -- 1880 01:12:29,480 --> 01:12:35,680 SOME OF YOU MAY HAVE SEEN, JUST 1881 01:12:35,680 --> 01:12:37,320 RELEASED A FUNDING ANNOUNCEMENT, 1882 01:12:37,320 --> 01:12:40,400 AND THIS MAY BE I GUESS PERHAPS 1883 01:12:40,400 --> 01:12:41,360 OUR LAST BIG FUNDING 1884 01:12:41,360 --> 01:12:42,720 ANNOUNCEMENT THAT WE DO, 1885 01:12:42,720 --> 01:12:44,120 ALTHOUGH WE'RE HOPING WE'LL BE 1886 01:12:44,120 --> 01:12:46,120 ABLE TO CONTINUE RADx TYPES OF 1887 01:12:46,120 --> 01:12:49,680 FUNDING PROGRAMS BUT THIS IS UP 1888 01:12:49,680 --> 01:12:53,080 TO $300 MILLION, AND THE ORIGIN 1889 01:12:53,080 --> 01:12:55,120 OF FUNDS, AGAIN, ARE IN THE 1890 01:12:55,120 --> 01:12:57,200 SUPPLEMENTAL APPROPRIATIONS THAT 1891 01:12:57,200 --> 01:12:58,640 WE WERE ABLE TO RECEIVE BUT 1892 01:12:58,640 --> 01:13:00,360 BASED ON WHERE WE ARE CURRENTLY 1893 01:13:00,360 --> 01:13:05,080 IN THE PANDEMIC AND AS JILL 1894 01:13:05,080 --> 01:13:07,360 POINTED OUT THE HUGE CHALLENGE 1895 01:13:07,360 --> 01:13:12,720 FOR HAVING ACCESSIBLE TEST 1896 01:13:12,720 --> 01:13:15,320 TECHNOLOGIES CLEARLY MANY 1897 01:13:15,320 --> 01:13:16,760 WELL-ESTABLISHED DESIGNS THAT 1898 01:13:16,760 --> 01:13:19,680 HAVE BEEN IN OPERATION FOR 1899 01:13:19,680 --> 01:13:22,000 SEVERAL DECADES WERE EASIER TO 1900 01:13:22,000 --> 01:13:24,320 DEVELOP QUICKLY AND DISSEMINATE 1901 01:13:24,320 --> 01:13:24,760 WIDELY. 1902 01:13:24,760 --> 01:13:26,200 AND I THINK CERTAINLY NONE OF US 1903 01:13:26,200 --> 01:13:28,680 EXPECTED AT THE BEGINNING OF THE 1904 01:13:28,680 --> 01:13:30,040 PANDEMIC THAT IN FEBRUARY OF 1905 01:13:30,040 --> 01:13:33,320 2022 THERE WOULD BE A BILLION 1906 01:13:33,320 --> 01:13:34,520 TESTS THAT WERE DISTRIBUTED OVER 1907 01:13:34,520 --> 01:13:37,800 THE COUNTER, AND THAT OUR EFFORT 1908 01:13:37,800 --> 01:13:39,760 WOULD BE DIRECTLY IMPACTFUL IN 1909 01:13:39,760 --> 01:13:41,400 THIS KIND OF DEVELOPMENT AND 1910 01:13:41,400 --> 01:13:42,960 PARADIGM SHIFT IN TESTING 1911 01:13:42,960 --> 01:13:45,000 TECHNOLOGIES, BUT THAT IS OUT 1912 01:13:45,000 --> 01:13:47,280 THERE NOW, SO AS WE STEP BACK 1913 01:13:47,280 --> 01:13:49,360 AND TAKE A LOOK AT WHAT ARE THE 1914 01:13:49,360 --> 01:13:50,680 MAJOR CHALLENGES, NUMBER ONE, 1915 01:13:50,680 --> 01:13:54,080 IT'S REALLY TO RAISE THE GAME ON 1916 01:13:54,080 --> 01:13:54,560 ACCESSIBILITY. 1917 01:13:54,560 --> 01:13:55,840 AND SO WITHIN THIS INNOVATION 1918 01:13:55,840 --> 01:13:58,440 FUNNEL THERE ARE TWO INNOVATION 1919 01:13:58,440 --> 01:14:01,000 FUNNELS WE RECENTLY ANNOUNCED. 1920 01:14:01,000 --> 01:14:03,240 THE FIRST IS IN ACCESSIBLE 1921 01:14:03,240 --> 01:14:04,520 TECHNOLOGY DESIGNED FOR 1922 01:14:04,520 --> 01:14:07,160 INDEPENDENT USE BY PEOPLE WITH 1923 01:14:07,160 --> 01:14:07,920 DISABILITIES. 1924 01:14:07,920 --> 01:14:11,760 AND ALL THE KEY CHALLENGES, JILL 1925 01:14:11,760 --> 01:14:12,680 HAS SUMMARIZED BEAUTIFULLY WHAT 1926 01:14:12,680 --> 01:14:17,800 WE'D LIKE TO SEE WITH THESE THAT 1927 01:14:17,800 --> 01:14:20,160 THE SUCCESSFUL ONES WILL BE 1928 01:14:20,160 --> 01:14:23,840 EASIER TO USE BUT WE'RE NOT 1929 01:14:23,840 --> 01:14:24,960 NECESSARILY REQUESTING WITHIN 1930 01:14:24,960 --> 01:14:27,920 THE DESIGN PERIOD FOR THE 1931 01:14:27,920 --> 01:14:30,040 PERFORMANCE TO BE SUBSTANTIALLY 1932 01:14:30,040 --> 01:14:31,680 BETTER AT INVESTING CLASS 1933 01:14:31,680 --> 01:14:32,400 CURRENT TECHNOLOGIES ALTHOUGH AS 1934 01:14:32,400 --> 01:14:34,440 YOU'LL SEE IN THE NEXT CHALLENGE 1935 01:14:34,440 --> 01:14:38,240 THAT'S WHAT WE'RE AFTER. 1936 01:14:38,240 --> 01:14:40,200 AND SO SUCCESSFUL PLATFORMS NEED 1937 01:14:40,200 --> 01:14:42,000 TO ACHIEVE SOME REGULAR STANDARD 1938 01:14:42,000 --> 01:14:42,840 REGULATORY EXPERIENCE, THIS IS 1939 01:14:42,840 --> 01:14:44,360 SOMETHING THAT WE'RE HOPING FOR 1940 01:14:44,360 --> 01:14:45,680 THE LONG TERM TO STIMULATE A 1941 01:14:45,680 --> 01:14:48,200 MAJOR CHANGE IN THE FIELD. 1942 01:14:48,200 --> 01:14:51,360 AND THE COMPANION PIECE TO THIS 1943 01:14:51,360 --> 01:14:56,280 IS TRYING TO DRIVE FORWARD NEXT 1944 01:14:56,280 --> 01:14:58,880 GEN -- TRULY NEXT GENERATION 1945 01:14:58,880 --> 01:14:59,680 TECHNOLOGIES WITH INNOVATIONS 1946 01:14:59,680 --> 01:15:01,680 THAT SIGNIFICANTLY IMPROVE THE 1947 01:15:01,680 --> 01:15:03,160 CLINICAL AND TECHNICAL 1948 01:15:03,160 --> 01:15:04,040 PERFORMANCE. 1949 01:15:04,040 --> 01:15:07,400 BUT THESE CAN'T BE INTRODUCED 1950 01:15:07,400 --> 01:15:08,400 WITHOUT INSPIRATION AND 1951 01:15:08,400 --> 01:15:09,720 ATTENTION TO CHALLENGE NUMBER 1952 01:15:09,720 --> 01:15:11,840 ONE, WHICH IS TO HAVE UNIVERSAL 1953 01:15:11,840 --> 01:15:13,320 DESIGN FEATURES AND 1954 01:15:13,320 --> 01:15:14,400 ACCESSIBILITY FOR ALL. 1955 01:15:14,400 --> 01:15:16,800 WE'D LIKE TO SEE THESE 1956 01:15:16,800 --> 01:15:17,760 TECHNOLOGIES ALSO INCORPORATE 1957 01:15:17,760 --> 01:15:19,880 SOME OF OUR DIGITAL HEALTH 1958 01:15:19,880 --> 01:15:24,360 REPORTING STANDARDS, I THINK ALL 1959 01:15:24,360 --> 01:15:26,760 OF YOU HAVE FOLLOWED THE GAP IN 1960 01:15:26,760 --> 01:15:29,360 TERMS OF INFORMATION AND 1961 01:15:29,360 --> 01:15:31,760 REPORTABILITY OF 1962 01:15:31,760 --> 01:15:33,520 OVER-THE-COUNTER TESTS. 1963 01:15:33,520 --> 01:15:34,720 THE RADx MOBILE APPLICATION 1964 01:15:34,720 --> 01:15:35,840 REPORTING STANDARD SYSTEM, MARS, 1965 01:15:35,840 --> 01:15:36,680 ADDRESSED THAT GAP. 1966 01:15:36,680 --> 01:15:39,280 AND WE'D LIKE TO SEE NEW 1967 01:15:39,280 --> 01:15:42,360 TECHNOLOGIES BUILT IN AT THE 1968 01:15:42,360 --> 01:15:43,360 FOUNDATION AND REALLY PROVIDE 1969 01:15:43,360 --> 01:15:46,320 KIND OF THE NEXT GENERATION OF 1970 01:15:46,320 --> 01:15:47,000 TECHNOLOGIC PERFORMANCE AND 1971 01:15:47,000 --> 01:15:47,640 COMMUNICATION FOR PERSONAL 1972 01:15:47,640 --> 01:15:49,920 HEALTH AS WELL AS PUBLIC HEALTH. 1973 01:15:49,920 --> 01:15:52,320 WE'D LIKE TO SEE THESE 1974 01:15:52,320 --> 01:15:53,320 TECHNOLOGIES ELIMINATE THE NEED 1975 01:15:53,320 --> 01:15:56,320 OR REDUCE THE NEED FOR SERIAL 1976 01:15:56,320 --> 01:15:59,080 TESTING, AGAIN I PRESENTED AT 1977 01:15:59,080 --> 01:16:00,000 THE LAST COUNCIL MEETING, YOU 1978 01:16:00,000 --> 01:16:01,480 MAY HAVE FOLLOWED THIS. 1979 01:16:01,480 --> 01:16:02,880 RAPID ANTIGEN TESTS ARE TERRIFIC 1980 01:16:02,880 --> 01:16:04,440 IF YOU HAVE A LOT OF VIRUS IN 1981 01:16:04,440 --> 01:16:06,400 YOU BUT IF YOU'RE STILL ON AN 1982 01:16:06,400 --> 01:16:08,240 ASCENDING PORTION OF YOUR 1983 01:16:08,240 --> 01:16:10,400 INFECTION YOU MAY HAVE A 1984 01:16:10,400 --> 01:16:10,960 NEGATIVE TEST. 1985 01:16:10,960 --> 01:16:12,520 IT'S IMPORTANT THAT YOU HAVE TWO 1986 01:16:12,520 --> 01:16:14,920 TESTS THAT ARE SEPARATED BY 48 1987 01:16:14,920 --> 01:16:15,800 HOURS IF YOU'RE SYMPTOMATIC IN 1988 01:16:15,800 --> 01:16:18,200 ORDER TO HAVE THE HIGHEST 1989 01:16:18,200 --> 01:16:20,080 PROBABILITY OF GETTING A 1990 01:16:20,080 --> 01:16:20,960 POSITIVE RESULT. 1991 01:16:20,960 --> 01:16:24,080 SO, WE'D LIKE TO SEE THE LIMITS 1992 01:16:24,080 --> 01:16:25,760 OF DETECTION EVEN WAY BETTER BY 1993 01:16:25,760 --> 01:16:27,720 AT LEAST AN ORDER OF MAGNITUDE, 1994 01:16:27,720 --> 01:16:29,040 IF NOT MORE. 1995 01:16:29,040 --> 01:16:31,320 AND THE EASE OF USE BE 1996 01:16:31,320 --> 01:16:33,400 SUBSTANTIALLY IMPROVED WITH THE 1997 01:16:33,400 --> 01:16:34,080 TWO FUNDING ANNOUNCEMENTS, GOING 1998 01:16:34,080 --> 01:16:35,840 LIVE ON THE 20th OF SEPTEMBER, 1999 01:16:35,840 --> 01:16:37,760 AND YOU CAN TAKE A LOOK AT THIS. 2000 01:16:37,760 --> 01:16:40,720 IT'S ON OUR BANNER PAGE ON OUR 2001 01:16:40,720 --> 01:16:41,200 WEBSITE. 2002 01:16:41,200 --> 01:16:44,240 AND FINALLY JUST THE LAST PIECE 2003 01:16:44,240 --> 01:16:46,520 OF NEWS AND UPDATE, I THINK 2004 01:16:46,520 --> 01:16:48,640 EVERYONE'S BEEN FOLLOWING AS WE 2005 01:16:48,640 --> 01:16:50,440 HAVE BEEN DISCUSSING IN ALL OF 2006 01:16:50,440 --> 01:16:52,520 OUR COUNCIL MEETINGS THE NEED TO 2007 01:16:52,520 --> 01:16:54,640 LEVERAGE ALL THE WORK THAT WE'VE 2008 01:16:54,640 --> 01:16:56,840 DONE IN COVID TESTING TO OTHER 2009 01:16:56,840 --> 01:16:57,440 PATHOGENS AND DISEASES. 2010 01:16:57,440 --> 01:16:59,320 AND ONE OF THE FIRST MAJOR 2011 01:16:59,320 --> 01:17:04,920 CHALLENGES THAT'S COME UP IS FOR 2012 01:17:04,920 --> 01:17:07,320 MONKEYPOX, AND PROBABLY YOU'VE 2013 01:17:07,320 --> 01:17:08,440 ALL FOLLOWED THE FRUSTRATING 2014 01:17:08,440 --> 01:17:13,040 ROLLOUT OF THE TESTING 2015 01:17:13,040 --> 01:17:13,360 TECHNOLOGIES. 2016 01:17:13,360 --> 01:17:15,000 SEEMED LIKE DEJA VU ALL OVER 2017 01:17:15,000 --> 01:17:17,200 AGAIN WITH ONLY A FEW 2018 01:17:17,200 --> 01:17:20,880 LABORATORIES DOING THESE, LONG 2019 01:17:20,880 --> 01:17:22,120 TURNAROUND ITEMS, MULTI-STEP 2020 01:17:22,120 --> 01:17:24,320 COMPLICATED TESTS, AS WE 2021 01:17:24,320 --> 01:17:25,560 PARTICIPATED IN MANY EVENTS 2022 01:17:25,560 --> 01:17:27,120 ACROSS THE GOVERNMENT TO DISCUSS 2023 01:17:27,120 --> 01:17:28,080 THIS UNFORTUNATELY WE WERE 2024 01:17:28,080 --> 01:17:32,320 CONSTRAINED FROM BEING ABLE TO 2025 01:17:32,320 --> 01:17:33,560 INVEST COVID FUNDS FOR MONKEYPOX 2026 01:17:33,560 --> 01:17:34,880 TEST DEVELOPMENT WHICH WE FELT 2027 01:17:34,880 --> 01:17:35,880 LIKE WE COULD IMMEDIATELY 2028 01:17:35,880 --> 01:17:37,840 LEVERAGE ALL THE ACTIVITIES FROM 2029 01:17:37,840 --> 01:17:39,600 COVID, BUT WE'VE BEEN ABLE TO 2030 01:17:39,600 --> 01:17:41,320 GET A MODEST AMOUNT OF NEW 2031 01:17:41,320 --> 01:17:44,360 RESOURCES FROM THE OFFICE OF THE 2032 01:17:44,360 --> 01:17:49,520 DIRECTOR AT THE NIH, TO INVEST 2033 01:17:49,520 --> 01:17:50,840 IN OUR ITA, OUR PARTNERSHIP WITH 2034 01:17:50,840 --> 01:17:53,440 FDA AND CAN YOU SEE THIS ON OUR 2035 01:17:53,440 --> 01:18:00,840 WEBSITE, THIS IS A NEW 2036 01:18:00,840 --> 01:18:01,720 OPPORTUNITY FOR ACCELERATING 2037 01:18:01,720 --> 01:18:04,560 REGULATORY PRICE IN POINT OF 2038 01:18:04,560 --> 01:18:14,760 CARE NUCLEIC ACID TEST, RAPID 2039 01:18:14,760 --> 01:18:15,680 ANTIGEN AND AT-HOME TESTING 2040 01:18:15,680 --> 01:18:16,520 KITS, NOT AUTHORIZED IN THE 2041 01:18:16,520 --> 01:18:18,040 UNITED STATES FOR MONKEYPOX. 2042 01:18:18,040 --> 01:18:20,680 THERE'S A BIG GAP MOVING TESTING 2043 01:18:20,680 --> 01:18:22,480 TECHNOLOGIES INTO THESE DOMAINS 2044 01:18:22,480 --> 01:18:23,680 WHEN NEW PATHOGENS COME UP. 2045 01:18:23,680 --> 01:18:26,000 WE HOPE WE CAN FILL THAT GAP 2046 01:18:26,000 --> 01:18:27,080 FIRST WITH MONKEYPOX AND FOR 2047 01:18:27,080 --> 01:18:30,600 OTHERS THAT WILL BE EMERGING. 2048 01:18:30,600 --> 01:18:33,520 SO, WITH THAT, I CAN STOP 2049 01:18:33,520 --> 01:18:35,000 SHARING AND I THINK THAT 2050 01:18:35,000 --> 01:18:37,080 SUMMARIZES, WE HIT YOU WITH A 2051 01:18:37,080 --> 01:18:39,120 LOT OF STUFF, PROBABLY AND 2052 01:18:39,120 --> 01:18:40,240 OVERWHELMING AMOUNT. 2053 01:18:40,240 --> 01:18:43,840 BUT WE CAN PIVOT TO QUESTIONS. 2054 01:18:43,840 --> 01:18:49,200 2055 01:18:49,200 --> 01:18:50,840 >> THANK YOU, BRUCE AND JILL. 2056 01:18:50,840 --> 01:18:52,600 QUESTIONS AND COMMENTS FROM THE 2057 01:18:52,600 --> 01:18:53,360 COUNCIL MEMBERS? 2058 01:18:53,360 --> 01:19:03,280 WE'D LOVE TO HEAR YOUR THOUGHTS. 2059 01:19:03,280 --> 01:19:06,040 I SEE MARYELLEN. 2060 01:19:06,040 --> 01:19:06,480 >> HI. 2061 01:19:06,480 --> 01:19:07,880 THANK YOU, BRUCE. 2062 01:19:07,880 --> 01:19:09,400 AS ALWAYS, AMAZING AMOUNT OF 2063 01:19:09,400 --> 01:19:12,040 WORK COMING OUT OF NIBIB. 2064 01:19:12,040 --> 01:19:13,880 FIRST I'M GOING TO MISS THESE 2065 01:19:13,880 --> 01:19:14,280 MEETINGS. 2066 01:19:14,280 --> 01:19:15,720 I'VE LEARNED A LOT AT ALL OF 2067 01:19:15,720 --> 01:19:16,160 THEM. 2068 01:19:16,160 --> 01:19:18,640 SO THANK YOU ALL FOR HAVING ME 2069 01:19:18,640 --> 01:19:19,680 HERE FOR THESE YEARS. 2070 01:19:19,680 --> 01:19:21,720 AND THEN I ALSO WANT TO THANK 2071 01:19:21,720 --> 01:19:24,280 YOU PUBLICLY FOR ALL YOUR 2072 01:19:24,280 --> 01:19:26,520 SUPPORT, EVERYONE AT NIBIB, OF 2073 01:19:26,520 --> 01:19:27,440 MIDRC. 2074 01:19:27,440 --> 01:19:29,080 IT'S A TEAM EFFORT. 2075 01:19:29,080 --> 01:19:31,080 IT'S 100 MORE PEOPLE BESIDES ME. 2076 01:19:31,080 --> 01:19:37,920 ALSO, I WANT TO POINT OUT THAT 2077 01:19:37,920 --> 01:19:38,880 THAT LISTENING TO NEWER 2078 01:19:38,880 --> 01:19:40,880 CHALLENGES THAT I HOPE IMAGING 2079 01:19:40,880 --> 01:19:42,640 CAN SNEAK AND GET IN THOSE TOO 2080 01:19:42,640 --> 01:19:45,480 AND I'LL BE HERE PUSHING ON THE 2081 01:19:45,480 --> 01:19:47,120 SIDELINES FOR THAT. 2082 01:19:47,120 --> 01:19:53,240 I THINK THE MULTIOMICS IMAGING 2083 01:19:53,240 --> 01:19:55,680 WITH OTHER CHARACTERISTICS, EHI 2084 01:19:55,680 --> 01:19:57,080 AND OTHERS ARE THE WAY TO GO. 2085 01:19:57,080 --> 01:19:58,440 GREAT THEY ARE STARTED. 2086 01:19:58,440 --> 01:20:00,760 ALSO TO JILL AND YOU, I WANT TO 2087 01:20:00,760 --> 01:20:02,200 TELL YOU, I APPRECIATE HOW 2088 01:20:02,200 --> 01:20:05,600 YOU'RE INCORPORATING THE USER 2089 01:20:05,600 --> 01:20:07,520 FEEDBACK INTO -- YES, YOU 2090 01:20:07,520 --> 01:20:08,200 SUCCESSFULLY DEVELOPED HOME 2091 01:20:08,200 --> 01:20:11,040 TESTS BUT NOW YOU'RE EVEN GOING 2092 01:20:11,040 --> 01:20:12,680 FURTHER WITH THEM AND 2093 01:20:12,680 --> 01:20:13,320 INCORPORATING EVERYONE'S 2094 01:20:13,320 --> 01:20:13,840 FEEDBACK. 2095 01:20:13,840 --> 01:20:16,640 I'VE BEEN A USER OF THOSE, SO I 2096 01:20:16,640 --> 01:20:19,760 APPRECIATE THAT TOO BUT ALSO 2097 01:20:19,760 --> 01:20:20,160 SCIENCE. 2098 01:20:20,160 --> 01:20:23,200 ALSO TO POINT OUT HOW RAPIDLY 2099 01:20:23,200 --> 01:20:24,600 YOU'VE GONE TO STANDARDIZING. 2100 01:20:24,600 --> 01:20:26,240 YOU KNOW, EVERYTHING WE DO, WE 2101 01:20:26,240 --> 01:20:29,080 NEED TO STANDARDIZE TO MAKE IT 2102 01:20:29,080 --> 01:20:29,440 UNIVERSAL. 2103 01:20:29,440 --> 01:20:30,400 I APPRECIATE THAT. 2104 01:20:30,400 --> 01:20:36,400 THAT'S ALL THE COMMENTS I HAD. 2105 01:20:36,400 --> 01:20:38,640 THANK YOU. 2106 01:20:38,640 --> 01:20:39,120 >> THANKS, MARYELLEN. 2107 01:20:39,120 --> 01:20:40,840 ALL OF THIS IS IS DESIGNED TO 2108 01:20:40,840 --> 01:20:44,640 PARTNER WITH ALL OF YOU. 2109 01:20:44,640 --> 01:20:47,400 YOU'RE THE LEADERS AND TO GIVE 2110 01:20:47,400 --> 01:20:49,760 MORE FEEDBACK ON HOW TO TAKE THE 2111 01:20:49,760 --> 01:20:50,880 BASIC PRINCIPLES AND IMPACT IN 2112 01:20:50,880 --> 01:20:51,960 OTHER AREAS AND LOOK FORWARD TO 2113 01:20:51,960 --> 01:20:54,080 WORKING WITH YOU ON THAT, 2114 01:20:54,080 --> 01:20:55,320 PARTICULARLY IMAGING. 2115 01:20:55,320 --> 01:20:58,400 BUT IT WAS ASTOUNDING TO BE IN 2116 01:20:58,400 --> 01:20:59,720 THE LISTENING SESSIONS IN ABOUT 2117 01:20:59,720 --> 01:21:04,640 30 SECONDS OF BEING IN ONE OF 2118 01:21:04,640 --> 01:21:05,600 THE LITTLE SMALLER WORKING 2119 01:21:05,600 --> 01:21:08,280 GROUPS IT HIT ME THESE TESTS ARE 2120 01:21:08,280 --> 01:21:12,920 ACTUALLY PRETTY HARD TO DO. 2121 01:21:12,920 --> 01:21:15,080 SOME HAVE SOMETHING LIKE 20 2122 01:21:15,080 --> 01:21:16,080 STEPS, PULL THE DIRECTIONS OUT, 2123 01:21:16,080 --> 01:21:17,640 DO THIS AND THIS AND THIS. 2124 01:21:17,640 --> 01:21:19,000 IT'S CLEAR WE CAN DO BETTER. 2125 01:21:19,000 --> 01:21:24,400 OUR COMMUNITY IS THE ONE TO MAKE 2126 01:21:24,400 --> 01:21:34,080 THAT HAPPEN. 2127 01:21:34,080 --> 01:21:39,640 >> I SEE KATHY AND RANU PLEASE. 2128 01:21:39,640 --> 01:21:40,480 >> YES, FIRST VERY IMPRESSIVE, 2129 01:21:40,480 --> 01:21:44,120 THE AMOUNT OF WORK THAT'S 2130 01:21:44,120 --> 01:21:45,200 HAPPENING. 2131 01:21:45,200 --> 01:21:46,440 ALSO, THE COLLABORATIONS ACROSS 2132 01:21:46,440 --> 01:21:49,480 AGENCIES, I THINK IT'S 2133 01:21:49,480 --> 01:21:50,000 IMPRESSIVE, PARTICULARLY 2134 01:21:50,000 --> 01:21:53,080 EXCITING CONTINUOUS HOW YOU 2135 01:21:53,080 --> 01:21:54,000 LEVERAGED INNOVATION FUNNEL 2136 01:21:54,000 --> 01:21:55,560 CONCEPT, ABLE TO APPLY THAT TO 2137 01:21:55,560 --> 01:21:57,240 NO CHALLENGES AS THEY COME ALONG 2138 01:21:57,240 --> 01:21:59,640 AND SUCCEED THERE. 2139 01:21:59,640 --> 01:22:01,240 I GUESS, A, THAT'S IMPRESSIVE, 2140 01:22:01,240 --> 01:22:02,680 I'M EXCITED ABOUT THAT. 2141 01:22:02,680 --> 01:22:04,800 B, I'M WONDERING IF THERE'S A 2142 01:22:04,800 --> 01:22:09,280 WAY OR WHAT OPPORTUNITIES THERE 2143 01:22:09,280 --> 01:22:13,280 MIGHT BE TO SHOW THE PUBLIC HOW 2144 01:22:13,280 --> 01:22:14,600 SUCCESSFUL IT'S BEEN AND THE 2145 01:22:14,600 --> 01:22:18,400 VISION OF MOVING FOR QUICKLY, 2146 01:22:18,400 --> 01:22:22,600 FROM DEVELOPMENT INTO THE CLINIC 2147 01:22:22,600 --> 01:22:23,200 AND APPLICATION. 2148 01:22:23,200 --> 01:22:25,080 >> THAT'S A GOOD POINT. 2149 01:22:25,080 --> 01:22:26,520 I THINK I WOULD TURN A LOT OF 2150 01:22:26,520 --> 01:22:29,120 THAT BACK ON TO YOU, YOU GUYS, 2151 01:22:29,120 --> 01:22:32,280 TO HELP REPEAT THIS STORY. 2152 01:22:32,280 --> 01:22:33,680 AND I MEAN WE'RE DOING THAT AS 2153 01:22:33,680 --> 01:22:35,880 BEST AS WE CAN. 2154 01:22:35,880 --> 01:22:38,000 I THINK WHAT'S REALLY 2155 01:22:38,000 --> 01:22:41,280 INTERESTING, WE'VE BEEN PLANNING 2156 01:22:41,280 --> 01:22:47,200 FOR SUPPLEMENTS TO GO AWAY, 2157 01:22:47,200 --> 01:22:47,880 $1.7 BILLION THAT SHOULD 2158 01:22:47,880 --> 01:22:48,920 DISAPPEAR, IT'S POSSIBLE IN ALL 2159 01:22:48,920 --> 01:22:50,440 OF THIS WORK WE'VE BECOME SORT 2160 01:22:50,440 --> 01:22:54,960 OF LIKE THE SWAT TEAM ACROSS 2161 01:22:54,960 --> 01:22:55,360 GOVERNMENT. 2162 01:22:55,360 --> 01:22:56,560 YOU KNOW, THE GO-TO GROUP THAT 2163 01:22:56,560 --> 01:22:58,080 CAN SOLVE PROBLEMS NOT PLANNED, 2164 01:22:58,080 --> 01:23:00,400 THE ONES THAT KEEP COMING UP. 2165 01:23:00,400 --> 01:23:03,880 SO, WE MAY GET MORE SUPPLEMENTAL 2166 01:23:03,880 --> 01:23:05,000 FUNDING IN THE FUTURE TO 2167 01:23:05,000 --> 01:23:08,880 ACTUALLY CONTINUE IN THAT ROLE. 2168 01:23:08,880 --> 01:23:10,880 WE'VE REVEALED A HUGE GAP IN THE 2169 01:23:10,880 --> 01:23:12,200 CAPABILITY OF THE COUNTRY TO 2170 01:23:12,200 --> 01:23:14,080 DE-RISK THINGS WHEN THERE'S NOT 2171 01:23:14,080 --> 01:23:15,360 FULLY A COMMERCIAL MARKET FOR IT 2172 01:23:15,360 --> 01:23:16,720 WHICH IS JUST -- THAT'S JUST 2173 01:23:16,720 --> 01:23:17,680 WHAT OUR COMMUNITY DOES. 2174 01:23:17,680 --> 01:23:18,840 WE KNOW THIS. 2175 01:23:18,840 --> 01:23:21,040 THIS IS JUST OUR PEOPLE DOING 2176 01:23:21,040 --> 01:23:25,480 WHAT WE DO. 2177 01:23:25,480 --> 01:23:27,320 SO, BUT THE $8 MILLION FUNNEL 2178 01:23:27,320 --> 01:23:29,680 WITH NICHD IS KIND OF OUR WORST 2179 01:23:29,680 --> 01:23:31,080 CASE SCENARIO PLANNING FOR THE 2180 01:23:31,080 --> 01:23:33,200 FUTURE WHERE WE HAVE NO 2181 01:23:33,200 --> 01:23:36,440 SUPPLEMENTAL FUNDS, CAN WE FORM 2182 01:23:36,440 --> 01:23:38,280 PARTNERSHIPS WITH OTHER 2183 01:23:38,280 --> 01:23:38,960 INSTITUTES THAT, REMEMBER, OUR 2184 01:23:38,960 --> 01:23:41,880 BUDGET IS I MEAN JUST BY 2185 01:23:41,880 --> 01:23:42,840 COMPARISON, NIAID IS $6 BILLION 2186 01:23:42,840 --> 01:23:45,680 PER YEAR SO THEY SHOULD BE ABLE 2187 01:23:45,680 --> 01:23:47,200 TO FIND $6 MILLION TO WORK ON 2188 01:23:47,200 --> 01:23:48,600 PROBLEMS THAT THEY ARE 2189 01:23:48,600 --> 01:23:49,640 INTERESTED IN. 2190 01:23:49,640 --> 01:23:52,520 SO WE'RE KIND OF LIKE THE LEAN 2191 01:23:52,520 --> 01:23:54,400 START-UP, YOU KNOW, LOOKING FOR 2192 01:23:54,400 --> 01:23:55,960 BUSINESS DEVELOPMENT 2193 01:23:55,960 --> 01:23:56,760 OPPORTUNITIES WITH OTHER 2194 01:23:56,760 --> 01:24:00,360 INSTITUTES AND CENTERS AND WE 2195 01:24:00,360 --> 01:24:01,680 WELCOME YOUR PERSONAL -- YOU 2196 01:24:01,680 --> 01:24:03,320 KNOW, THE AREAS YOU THINK ARE 2197 01:24:03,320 --> 01:24:06,080 AREAS OF NEED FOR US TO 2198 01:24:06,080 --> 01:24:07,880 POTENTIALLY DEPLOY THIS AND 2199 01:24:07,880 --> 01:24:09,440 YOU'RE ALL FUNDED BY OTHER 2200 01:24:09,440 --> 01:24:10,200 INSTITUTES AND CENTERS. 2201 01:24:10,200 --> 01:24:12,160 AND, YOU KNOW, THE WAY THIS 2202 01:24:12,160 --> 01:24:14,400 GROWS IS WHEN THE COMMUNITY 2203 01:24:14,400 --> 01:24:16,440 SAYS, HEY, WE NEED TO DRIVE AN 2204 01:24:16,440 --> 01:24:17,680 INNOVATION FUNNEL IN THIS 2205 01:24:17,680 --> 01:24:19,640 PARTICULAR AREA, AND SEE IF WE 2206 01:24:19,640 --> 01:24:21,680 CAN DE-RISK AND ACCELERATE AND 2207 01:24:21,680 --> 01:24:23,040 MOVE THINGS. 2208 01:24:23,040 --> 01:24:25,160 NICHD, MY LAB HAPPENS TO BE IN 2209 01:24:25,160 --> 01:24:25,360 NICHD. 2210 01:24:25,360 --> 01:24:27,680 WE HAVE REALLY GREAT 2211 01:24:27,680 --> 01:24:28,320 COLLABORATIVE RELATIONSHIPS WITH 2212 01:24:28,320 --> 01:24:33,640 DIANA BIANCHI, AND THEY HAVE 2213 01:24:33,640 --> 01:24:37,880 GRAVITATED DIRECTLY, ALLISONER 2214 01:24:37,880 --> 01:24:39,400 ALISON CERNICH IS DEPUTY 2215 01:24:39,400 --> 01:24:40,040 DIRECTOR, TECHNOLOGY SAVVY, AND 2216 01:24:40,040 --> 01:24:42,320 SO THIS WAS EASY FOR US TO DO. 2217 01:24:42,320 --> 01:24:44,560 IT'S TAKEN SOME TIME TO GET IT 2218 01:24:44,560 --> 01:24:44,840 LAUNCHED. 2219 01:24:44,840 --> 01:24:47,080 BUT WE HOPE TO JUST REPRODUCE 2220 01:24:47,080 --> 01:24:50,200 THAT, EVEN WITHOUT ANY 2221 01:24:50,200 --> 01:24:51,840 SUBSTANTIAL ADDITIONAL 2222 01:24:51,840 --> 01:24:56,760 SUPPLEMENTAL FUNDING. 2223 01:24:56,760 --> 01:24:57,720 >> THANK YOU. 2224 01:24:57,720 --> 01:24:59,960 I LOVE THE ZOOM FEATURES WITH 2225 01:24:59,960 --> 01:25:03,440 THE HANDS ORIENTING THE 2226 01:25:03,440 --> 01:25:04,080 PICTURES. 2227 01:25:04,080 --> 01:25:06,280 IT'S REAL EASY, RANU AND 2228 01:25:06,280 --> 01:25:07,400 JENNIFER. 2229 01:25:07,400 --> 01:25:09,240 >> BRUCE AND JILL, AGAIN, 2230 01:25:09,240 --> 01:25:10,320 CONGRATULATIONS FOR SUCH A 2231 01:25:10,320 --> 01:25:11,680 FANTASTIC JOB. 2232 01:25:11,680 --> 01:25:13,920 I'M REMINDED OF EARLIER ON WHEN 2233 01:25:13,920 --> 01:25:16,320 THE COUNCIL TALKED ABOUT HOW CAN 2234 01:25:16,320 --> 01:25:19,920 RADx BE -- HOW CAN THAT MODEL 2235 01:25:19,920 --> 01:25:21,800 BE MADE BETTER. 2236 01:25:21,800 --> 01:25:22,560 IT'S REALLY, REALLY GRATIFYING 2237 01:25:22,560 --> 01:25:23,880 TO SEE HOW YOU'VE BEEN ABLE TO 2238 01:25:23,880 --> 01:25:28,760 TAKE THAT AND PUT IT INTO 2239 01:25:28,760 --> 01:25:30,120 DIFFERENT PARTS, MANY PARTS. 2240 01:25:30,120 --> 01:25:35,400 THE LAST PART THAT JILL 2241 01:25:35,400 --> 01:25:36,440 MENTIONED, ACCESSIBILITY, IT 2242 01:25:36,440 --> 01:25:40,440 WOULD BE GREAT TO SEE THAT WHEN 2243 01:25:40,440 --> 01:25:42,080 WE'RE MAKING CAUSE FOR 2244 01:25:42,080 --> 01:25:43,680 TECHNOLOGY, ET CETERA, UP FRONT 2245 01:25:43,680 --> 01:25:48,200 WE TRY TO EMBED THAT INTO OUR 2246 01:25:48,200 --> 01:25:49,920 PROGRAM ITSELF SO THAT AT LEAST 2247 01:25:49,920 --> 01:25:51,480 PEOPLE ARE AWARE WHEN THEY ARE 2248 01:25:51,480 --> 01:25:52,680 MAKING THE TECHNOLOGY RIGHT FROM 2249 01:25:52,680 --> 01:25:57,280 THE GET-GO AND THAT WE DON'T END 2250 01:25:57,280 --> 01:25:58,560 UP WITH THIS COVID TEST ALL OF 2251 01:25:58,560 --> 01:26:00,120 US HAVE STRUGGLED WITH, MORE 2252 01:26:00,120 --> 01:26:01,720 THAN OTHERS, TO DO. 2253 01:26:01,720 --> 01:26:04,440 THE OTHER THING I WANTED TO ALSO 2254 01:26:04,440 --> 01:26:08,080 SEE IS THAT DIGITAL TWIN PROGRAM 2255 01:26:08,080 --> 01:26:11,680 THAT THE REPORTS ARE COMING OUT 2256 01:26:11,680 --> 01:26:12,560 FOR. 2257 01:26:12,560 --> 01:26:17,160 HOW COULD NIBIB BE PRO-ACTIVE 2258 01:26:17,160 --> 01:26:20,000 AND THINK ABOUT THAT ASPECT 2259 01:26:20,000 --> 01:26:22,960 BEING INTEGRATED INTO OUR EFFORT 2260 01:26:22,960 --> 01:26:25,560 AT SUPPORTING THE FUTURE FUNDING 2261 01:26:25,560 --> 01:26:27,240 MECHANISM BECAUSE OBVIOUSLY 2262 01:26:27,240 --> 01:26:29,200 THOSE REPORTS ARE COMING, THE 2263 01:26:29,200 --> 01:26:33,240 OPPORTUNITY WILL FOLLOW, ONE WAY 2264 01:26:33,240 --> 01:26:38,200 OR ANOTHER. 2265 01:26:38,200 --> 01:26:38,760 STRATEGICALLY THINKING ABOUT 2266 01:26:38,760 --> 01:26:41,760 THAT, THAT WOULD BE NICE. 2267 01:26:41,760 --> 01:26:43,480 GREAT JOB, A LOT HERE, SO 2268 01:26:43,480 --> 01:26:43,840 FANTASTIC. 2269 01:26:43,840 --> 01:26:45,280 >> JILL, DO YOU WANT TO SAY 2270 01:26:45,280 --> 01:26:46,000 SOMETHING ABOUT THE 2271 01:26:46,000 --> 01:26:47,880 TRANSFERABILITY OF THESE DESIGN 2272 01:26:47,880 --> 01:26:48,200 PRINCIPLES? 2273 01:26:48,200 --> 01:26:51,000 AND I'LL SAY SOMETHING ABOUT 2274 01:26:51,000 --> 01:26:53,080 DIGITAL TWINS? 2275 01:26:53,080 --> 01:26:53,320 >> SURE. 2276 01:26:53,320 --> 01:26:55,280 THANK YOU, RANU. 2277 01:26:55,280 --> 01:26:57,560 THAT'S EXACTLY OUR RESOLVE, TO 2278 01:26:57,560 --> 01:26:59,040 BUILD ACCESSIBILITY IN AT THE 2279 01:26:59,040 --> 01:27:01,680 GROUND FLOOR WITH EVERYTHING WE 2280 01:27:01,680 --> 01:27:02,440 DO. 2281 01:27:02,440 --> 01:27:03,960 AND WE'VE ALREADY INCORPORATED 2282 01:27:03,960 --> 01:27:07,800 THAT AS A KEY ASPECT OF HIGHER 2283 01:27:07,800 --> 01:27:08,440 PERFORMANCE TEST SOLICITATION 2284 01:27:08,440 --> 01:27:12,800 THAT WE JUST PUT OUT. 2285 01:27:12,800 --> 01:27:13,880 WE WANT COMPANIES TO THINK ABOUT 2286 01:27:13,880 --> 01:27:15,240 THIS RIGHT FROM THE BEGINNING 2287 01:27:15,240 --> 01:27:16,080 BECAUSE OUR EXPERIENCE TELLS 2288 01:27:16,080 --> 01:27:20,200 FUSS WE GO TO A COMPANY THAT'S 2289 01:27:20,200 --> 01:27:21,520 HAPPILY MANUFACTURING A TEST 2290 01:27:21,520 --> 01:27:22,760 THEY DON'T NECESSARILY WELCOME 2291 01:27:22,760 --> 01:27:24,680 THE IDEA, SOME DO, BUT THEY 2292 01:27:24,680 --> 01:27:25,840 DON'T ALL WELCOME THE IDEA OF 2293 01:27:25,840 --> 01:27:31,400 MAKING A CHANGE FOR THE SAKE OF 2294 01:27:31,400 --> 01:27:31,720 ACCESSIBILITY. 2295 01:27:31,720 --> 01:27:34,280 THIGH HE CAN YOU'RE RIGHT WE 2296 01:27:34,280 --> 01:27:36,440 HAVE TO JUST REALLY NORMALIZE 2297 01:27:36,440 --> 01:27:37,520 THAT APPROACH, AND THAT'S PART 2298 01:27:37,520 --> 01:27:41,880 OF WHY WE WANT TO MAKE THESE 2299 01:27:41,880 --> 01:27:43,880 MATERIALS AND TEMPLATES AND 2300 01:27:43,880 --> 01:27:44,840 GUIDELINES PUBLIC AND ACCESSIBLE 2301 01:27:44,840 --> 01:27:46,600 SO COMPANIES KNOW WHAT WE'RE 2302 01:27:46,600 --> 01:27:47,440 ASKING FOR. 2303 01:27:47,440 --> 01:27:48,880 AND I THINK THAT'S ONE OF THE 2304 01:27:48,880 --> 01:27:50,920 BEST THINGS THAT WILL COME OUT 2305 01:27:50,920 --> 01:27:52,680 OF THIS INITIAL FAST TRACK 2306 01:27:52,680 --> 01:27:55,680 EFFORT IS ALL THE LESSONS WE'RE 2307 01:27:55,680 --> 01:27:57,800 LEARNING AND WHAT WE'RE FINDING 2308 01:27:57,800 --> 01:28:00,880 OUT FROM THE ACCESSIBLE DESIGN 2309 01:28:00,880 --> 01:28:02,640 HOUSES, HOW TO THINK THAT WAY. 2310 01:28:02,640 --> 01:28:04,680 IF WE CAN CAPTURE THAT AND SHARE 2311 01:28:04,680 --> 01:28:09,120 IT, WE'VE DONE SOMETHING GOOD I 2312 01:28:09,120 --> 01:28:09,480 THINK. 2313 01:28:09,480 --> 01:28:10,360 THANK YOU. 2314 01:28:10,360 --> 01:28:13,520 >> YEAH, A QUICK COMMENT ABOUT 2315 01:28:13,520 --> 01:28:14,680 DIGITAL TWINS, RANU, I DON'T 2316 01:28:14,680 --> 01:28:15,640 WANT TO WAIT UNTIL THE REPORT 2317 01:28:15,640 --> 01:28:16,040 COMMENTS OUT. 2318 01:28:16,040 --> 01:28:19,040 GRACE HAS BEEN A HUGE LEADER AND 2319 01:28:19,040 --> 01:28:21,080 ADVOCATE IN THIS, AND THE BRIDGE 2320 01:28:21,080 --> 01:28:23,920 TO A.I. INITIATIVE WE WERE 2321 01:28:23,920 --> 01:28:26,200 HOPING THAT MORE DIGITAL TWIN 2322 01:28:26,200 --> 01:28:26,800 CONCEPTS WOULD COME THROUGH. 2323 01:28:26,800 --> 01:28:30,080 I DON'T KNOW IF AWARDS HAVE BEEN 2324 01:28:30,080 --> 01:28:30,680 ANNOUNCED YET BUT SUPPOSEDLY 2325 01:28:30,680 --> 01:28:32,440 THEY ARE COMING THIS MORNING. 2326 01:28:32,440 --> 01:28:33,560 HAS ANYBODY HAD A CHANCE TO LOOK 2327 01:28:33,560 --> 01:28:40,720 ONLINE TO SEE IF THEY POPPED UP? 2328 01:28:40,720 --> 01:28:41,880 >> YEAH, THEY ARE UP. 2329 01:28:41,880 --> 01:28:42,680 >> THEY ARE UP? 2330 01:28:42,680 --> 01:28:46,080 WE NEED TO DO THAT NOW. 2331 01:28:46,080 --> 01:28:47,680 I MEAN, WE'RE IMPATIENT. 2332 01:28:47,680 --> 01:28:50,920 WE'VE SEEN HOW THIS CAN 2333 01:28:50,920 --> 01:28:52,960 DRAMATICALLY IMPACT EVEN IMAGING 2334 01:28:52,960 --> 01:28:53,520 TECHNOLOGY DEVELOPMENT, FOR 2335 01:28:53,520 --> 01:28:55,960 EXAMPLE WHEN YOU LOOK AT HUGE 2336 01:28:55,960 --> 01:28:56,880 CLINICAL STUDIES DONE COMPARING 2337 01:28:56,880 --> 01:28:58,600 ONE INSTRUMENT TO THE OTHER, AND 2338 01:28:58,600 --> 01:29:05,440 THE ONE THAT COMES TO MIND IS 2339 01:29:05,440 --> 01:29:09,960 DIGITAL SYNTHESIS VERSUS DIGITAL 2340 01:29:09,960 --> 01:29:10,880 MAMMOGRAPHY, HUNDREDS OF 2341 01:29:10,880 --> 01:29:11,960 MILLIONS OF DOLLARS TO COMPARE 2342 01:29:11,960 --> 01:29:23,000 THE TWO, SOMETHING THAT CAN BE 2343 01:29:23,000 --> 01:29:24,720 FULLY DIGITALLY TWINNED, AN FDA 2344 01:29:24,720 --> 01:29:26,480 STUDY, COULD YOU IMMEDIATELY 2345 01:29:26,480 --> 01:29:29,520 GRASP DIFFERENCES IN A 2346 01:29:29,520 --> 01:29:31,720 QUANTITATIVE SENSE AND THAT 2347 01:29:31,720 --> 01:29:33,160 LITERALLY COULD HAVE SAVED, 2348 01:29:33,160 --> 01:29:35,760 GOODNESS, I DON'T WANT TO SAY 2349 01:29:35,760 --> 01:29:36,920 THE NUMBER. 2350 01:29:36,920 --> 01:29:38,640 BUT THERE IS ENORMOUS POTENTIAL 2351 01:29:38,640 --> 01:29:41,440 AND OPPORTUNITY THERE, NOT JUST 2352 01:29:41,440 --> 01:29:44,960 IN THE TECHNOLOGY BUT IN 2353 01:29:44,960 --> 01:29:46,720 BUILDING IN PREDICTIVE MODELS 2354 01:29:46,720 --> 01:29:51,840 FOR INTEGRATED PHYSIOLOGIC SAYS 2355 01:29:51,840 --> 01:29:53,000 ITEMS -- SYSTEMS. 2356 01:29:53,000 --> 01:29:55,440 EVERYONE WILL HAVE A DIGITAL 2357 01:29:55,440 --> 01:29:57,080 TWIN IN THE FUTURE BUT HE DON'T 2358 01:29:57,080 --> 01:29:58,280 WANT TO WAIT THAT LONG. 2359 01:29:58,280 --> 01:30:01,000 I TURN IT BACK TO YOU. 2360 01:30:01,000 --> 01:30:02,080 SEND IN SOME CONCEPTS AND 2361 01:30:02,080 --> 01:30:05,280 SUGGESTIONS IN THAT AREA AND 2362 01:30:05,280 --> 01:30:14,000 CONNECT WITH GRACE. 2363 01:30:14,000 --> 01:30:15,040 >> SAM AND JENNIFER? 2364 01:30:15,040 --> 01:30:17,880 >> WHAT I WAS TRYING TO SAY WAS 2365 01:30:17,880 --> 01:30:18,480 ADDRESSED. 2366 01:30:18,480 --> 01:30:22,360 THANK YOU, BRUCE, AN NIBIB FOR 2367 01:30:22,360 --> 01:30:23,600 WHAT YOU'RE DOING. 2368 01:30:23,600 --> 01:30:26,360 DELIGHTED TO SEE HOW YOU RESPOND 2369 01:30:26,360 --> 01:30:29,240 TO REQUESTS AND DEMANDS AND 2370 01:30:29,240 --> 01:30:30,080 OBSERVATIONS, FEEDBACK. 2371 01:30:30,080 --> 01:30:32,720 ALSO IN THE AREA OF HEALTH 2372 01:30:32,720 --> 01:30:34,840 DISPARITY, I WANT TO THANK YOU 2373 01:30:34,840 --> 01:30:37,760 SO MUCH FOR THE WAY YOU'VE 2374 01:30:37,760 --> 01:30:40,520 SPONSORED THE SITE PROJECTS TO 2375 01:30:40,520 --> 01:30:43,040 ADDRESS REALLY BIG PROBLEMS. 2376 01:30:43,040 --> 01:30:45,200 I THINK NIBIB'S WELL POSITIONED 2377 01:30:45,200 --> 01:30:55,280 TO ADDRESS THE ISSUE OF HEALTH 2378 01:30:55,280 --> 01:30:56,240 DISPARITIES, IN OPTICAL, WE KNOW 2379 01:30:56,240 --> 01:30:58,080 WHAT THAT MEANS. 2380 01:30:58,080 --> 01:31:02,360 WHEN WE DO CALIBRATIONS MOST 2381 01:31:02,360 --> 01:31:04,240 PEOPLE DO NOT CONSIDER VARIOUS 2382 01:31:04,240 --> 01:31:05,600 EFFECTS OF MELANIN IN RESPONSE 2383 01:31:05,600 --> 01:31:08,600 RATE OF OUR TECHNOLOGY. 2384 01:31:08,600 --> 01:31:10,040 SO NOW THAT WE'RE ADDRESSING 2385 01:31:10,040 --> 01:31:12,160 THOSE ISSUES, IT'S VERY 2386 01:31:12,160 --> 01:31:12,440 IMPORTANT. 2387 01:31:12,440 --> 01:31:15,040 I ALSO WANT TO TOUCH THE ISSUE 2388 01:31:15,040 --> 01:31:19,720 WITH DATABASE THAT WE'RE 2389 01:31:19,720 --> 01:31:20,680 GENERATING IN GENERAL. 2390 01:31:20,680 --> 01:31:26,440 WE KNOW A LOT OF FUNDERS, 2391 01:31:26,440 --> 01:31:27,400 MEDICAL SENDERS, RANGE OF 2392 01:31:27,400 --> 01:31:30,240 NORMALCY DEVELOPED MANY YEARS 2393 01:31:30,240 --> 01:31:32,440 AGO AND WE DEVOLVED A LOT. 2394 01:31:32,440 --> 01:31:35,680 SOME OF THEM ARE NOT REALLY AS 2395 01:31:35,680 --> 01:31:38,720 RELEVANT AS THEY USED TO BE. 2396 01:31:38,720 --> 01:31:40,280 IS IT TIME FOR NIBIB TO START 2397 01:31:40,280 --> 01:31:42,440 LOOKING INTO THAT AND SEEING HOW 2398 01:31:42,440 --> 01:31:45,320 WE CAN REDEFINE WHAT IS NORMAL 2399 01:31:45,320 --> 01:31:48,880 RANGE IN THE HEALTH CARE SPACE 2400 01:31:48,880 --> 01:31:52,280 RIGHT NOW? 2401 01:31:52,280 --> 01:31:55,880 >> I THINK THAT THAT IS ACTUALLY 2402 01:31:55,880 --> 01:31:58,720 TOP OF MIND FOR ALL OF NIH. 2403 01:31:58,720 --> 01:32:02,760 AND THAT IS ONE OF THE KEY 2404 01:32:02,760 --> 01:32:04,880 CONCEPTUAL FRAMEWORKS BEHIND 2405 01:32:04,880 --> 01:32:09,240 BRIDGE TO A.I. WHICH IS THAT 2406 01:32:09,240 --> 01:32:12,600 DATABASES NEED TO BE 2407 01:32:12,600 --> 01:32:13,600 REPRESENTATIVE AND ETHICAL 2408 01:32:13,600 --> 01:32:17,080 DATABASES THAT ARE NOT THE -- 2409 01:32:17,080 --> 01:32:18,880 THAT DON'T HAVE BUILT-IN 2410 01:32:18,880 --> 01:32:20,600 INTRINSIC BIAS, THAT'S AT THE 2411 01:32:20,600 --> 01:32:22,240 ABSOLUTE CENTER, THE CORE OF 2412 01:32:22,240 --> 01:32:22,440 MIDRC. 2413 01:32:22,440 --> 01:32:24,640 AND THAT'S, YOU KNOW, FROM THE 2414 01:32:24,640 --> 01:32:26,560 VERY FOUNDATION THE ORIGIN OF 2415 01:32:26,560 --> 01:32:26,840 THINKING. 2416 01:32:26,840 --> 01:32:31,880 WHAT'S SO BEAUTIFUL ABOUT MIDRC 2417 01:32:31,880 --> 01:32:34,240 IS IT'S ACTUALLY GOT THE RANGE 2418 01:32:34,240 --> 01:32:35,760 OF EXPERTISE FROM THE PHYSICISTS 2419 01:32:35,760 --> 01:32:38,480 WHO CARE ABOUT THE ORIGIN OF 2420 01:32:38,480 --> 01:32:40,680 EVERY VOXEL TO THE PHYSICIANS 2421 01:32:40,680 --> 01:32:42,760 WHO REALLY WANT TO MAKE 2422 01:32:42,760 --> 01:32:44,960 DIAGNOSIS AND IMPROVE THE 2423 01:32:44,960 --> 01:32:45,600 OUTCOME FOR PATIENT. 2424 01:32:45,600 --> 01:32:49,360 AND I THINK THAT'S THE KIND 2425 01:32:49,360 --> 01:32:51,120 OF -- FROM WHAT I FOUND ACROSS 2426 01:32:51,120 --> 01:32:54,480 THE NIH, PEOPLE MAY HAVE THE 2427 01:32:54,480 --> 01:32:56,760 AMBITION OF HAVING FAIR 2428 01:32:56,760 --> 01:32:58,080 DATABASES, REPRESENTATIVE 2429 01:32:58,080 --> 01:32:59,280 DATABASES, AND REALLY GOOD A.I. 2430 01:32:59,280 --> 01:33:03,760 BUT THEY DON'T ALWAYS HAVE THE 2431 01:33:03,760 --> 01:33:04,960 TECHNICAL KNOW-HOW OF HOW TO 2432 01:33:04,960 --> 01:33:07,680 REALLY ENSURE THAT THAT IS THE 2433 01:33:07,680 --> 01:33:07,960 CASE. 2434 01:33:07,960 --> 01:33:10,880 AND THEN DEVELOP THE RIGHT 2435 01:33:10,880 --> 01:33:11,080 TOOLS. 2436 01:33:11,080 --> 01:33:16,880 WE INSERTED OURSELVES IN THIS 2437 01:33:16,880 --> 01:33:19,040 RADX-UP COMPETITION, WHICH 2438 01:33:19,040 --> 01:33:23,520 PROPOSED TO DO AI APPROACHES IN 2439 01:33:23,520 --> 01:33:24,120 COVID DIAGNOSTICS. 2440 01:33:24,120 --> 01:33:26,040 FORTUNATELY, I WAS INVOLVED IN 2441 01:33:26,040 --> 01:33:27,360 THAT, AND OTHERS WERE, WE WERE 2442 01:33:27,360 --> 01:33:30,080 ABLE TO HELP SHAPE DIRECTIONS SO 2443 01:33:30,080 --> 01:33:33,040 THEY BUILT THOSE CONSIDERATIONS 2444 01:33:33,040 --> 01:33:34,360 OF THE TECHNICAL SMARTS, YOU 2445 01:33:34,360 --> 01:33:35,560 KNOW, AT THE FOUNDATION. 2446 01:33:35,560 --> 01:33:38,360 SO THE SPIRIT OF WHAT MARYELLEN 2447 01:33:38,360 --> 01:33:39,920 AND COLLEAGUES ARE DOING IN 2448 01:33:39,920 --> 01:33:43,520 MIDRC IS WHAT WE NEED TO EXPAND 2449 01:33:43,520 --> 01:33:44,400 AND ITS QUITE REPRESENTATIVE OF 2450 01:33:44,400 --> 01:33:48,280 THINGS THAT NEED TO GO ON ACROSS 2451 01:33:48,280 --> 01:33:49,760 THE NIH. 2452 01:33:49,760 --> 01:33:50,080 ABSOLUTELY. 2453 01:33:50,080 --> 01:33:52,600 AND YOU GUYS NEED TO KEEP 2454 01:33:52,600 --> 01:33:54,040 TELLING THAT STORY BECAUSE IT'S 2455 01:33:54,040 --> 01:33:57,000 A VERY, VERY IMPORTANT ONE TO 2456 01:33:57,000 --> 01:34:04,680 REPEAT. 2457 01:34:04,680 --> 01:34:05,600 >> THANK YOU, SAM. 2458 01:34:05,600 --> 01:34:06,080 JENNIFER? 2459 01:34:06,080 --> 01:34:08,760 >> THANK YOU FOR THAT EXCELLENT 2460 01:34:08,760 --> 01:34:11,480 PRESENTATION, ALL THE AMAZING 2461 01:34:11,480 --> 01:34:12,160 WORK. 2462 01:34:12,160 --> 01:34:14,120 SO, NOW THAT RADx HAS SHOWN 2463 01:34:14,120 --> 01:34:16,880 ITSELF TO BE A GREAT MECHANISM 2464 01:34:16,880 --> 01:34:19,360 AND COVID AND BEING EXTENDED TO 2465 01:34:19,360 --> 01:34:20,800 OTHER SPECIAL PROJECTS DO YOU 2466 01:34:20,800 --> 01:34:24,720 SEE THAT TYPE OF MODEL 2467 01:34:24,720 --> 01:34:27,040 PERMEATING ITS WAY INTO A 2468 01:34:27,040 --> 01:34:29,080 PERMANENT PART OF THE NIBIB 2469 01:34:29,080 --> 01:34:30,720 FUNDING PROFILE? 2470 01:34:30,720 --> 01:34:33,560 I LOVE THE IDEA OF FUNNELING 2471 01:34:33,560 --> 01:34:35,200 THINGS DOWN AND GIVING WHAT'S 2472 01:34:35,200 --> 01:34:36,760 ESSENTIALLY LIKE SEED GRANTS TO 2473 01:34:36,760 --> 01:34:39,680 PEOPLE WHO HAVE GOOD IDEAS THAT 2474 01:34:39,680 --> 01:34:40,880 DON'T MEET THE LEVEL OF 2475 01:34:40,880 --> 01:34:43,120 PRELIMINARY DATA YOU NEED TO BE 2476 01:34:43,120 --> 01:34:46,440 COMPETITIVE FOR AN R01. 2477 01:34:46,440 --> 01:34:47,880 >> JENNIFER, ABSOLUTELY. 2478 01:34:47,880 --> 01:34:49,760 YEAH, AND THAT WHOLE STRUCTURE, 2479 01:34:49,760 --> 01:34:51,280 YOU SHOULD TALK TO TAYLOR 2480 01:34:51,280 --> 01:34:53,920 BECAUSE HE'S COME UP WITH THE 2481 01:34:53,920 --> 01:34:55,280 PROCESS, THE INNOVATION IS IN 2482 01:34:55,280 --> 01:34:59,960 THE PROCESS, HOW TO USE MULTIPLE 2483 01:34:59,960 --> 01:35:02,960 STAGED AWARDS TO BE ABLE TO 2484 01:35:02,960 --> 01:35:03,600 REALLY RECAPITULATE THE WHOLE 2485 01:35:03,600 --> 01:35:03,880 FUNNEL. 2486 01:35:03,880 --> 01:35:05,880 A LOT OF THIS AS YOU ALL KNOW 2487 01:35:05,880 --> 01:35:09,040 COMES DOWN TO THE DETAILS OF HOW 2488 01:35:09,040 --> 01:35:10,280 YOU GET PEOPLE MONEY AND HOW 2489 01:35:10,280 --> 01:35:13,200 FAST YOU CAN DO THAT. 2490 01:35:13,200 --> 01:35:15,920 AND ALSO THE SORT OF MECHANISMS 2491 01:35:15,920 --> 01:35:18,240 THAT YOU USE TO EVALUATE THE 2492 01:35:18,240 --> 01:35:23,160 VALUE OF A CONCEPT AS IT 2493 01:35:23,160 --> 01:35:25,160 CONTINUES TO PROGRESS OVER ITS 2494 01:35:25,160 --> 01:35:26,760 ARC OF DEVELOPMENT. 2495 01:35:26,760 --> 01:35:28,960 WE HOPE TO COPY/PASTE THAT AND 2496 01:35:28,960 --> 01:35:31,040 EVERYONE I TALK TO AT ALL THE 2497 01:35:31,040 --> 01:35:32,360 OTHER INSTITUTES, WHENEVER I 2498 01:35:32,360 --> 01:35:34,440 SHOW THEM THAT, I SHOW THEM THE 2499 01:35:34,440 --> 01:35:37,240 COUPLE FIGURES, THEY ALL GO, 2500 01:35:37,240 --> 01:35:39,280 THIS IS GREAT, WE WANT TO DO IT 2501 01:35:39,280 --> 01:35:40,320 FOR XYZ. 2502 01:35:40,320 --> 01:35:43,640 WE'RE IN A POSITION NOW, BUT 2503 01:35:43,640 --> 01:35:46,120 THOSE INSTITUTES YOU ALL WORK 2504 01:35:46,120 --> 01:35:46,880 WITH ARE SUPER-SENSITIVE TO 2505 01:35:46,880 --> 01:35:47,320 THEIR COMMUNITIES. 2506 01:35:47,320 --> 01:35:50,200 SO I THINK YOU ALL CAN PROVIDE 2507 01:35:50,200 --> 01:35:51,040 FEEDBACK. 2508 01:35:51,040 --> 01:35:52,800 I MEAN, YOU'LL HEAR A 2509 01:35:52,800 --> 01:35:54,240 PRESENTATION AFTER THIS ON 2510 01:35:54,240 --> 01:35:57,560 TRYING TO EXTEND THIS IN SOME 2511 01:35:57,560 --> 01:36:00,320 WAYS THE LAST FRONTIER IS IN 2512 01:36:00,320 --> 01:36:02,080 BIOMATERIALS AND ENGINEERED 2513 01:36:02,080 --> 01:36:03,600 BIOLOGICAL SYSTEMS, WHICH ARE 2514 01:36:03,600 --> 01:36:05,880 NOT NECESSARILY AS FAR ALONG AS 2515 01:36:05,880 --> 01:36:06,560 THE HARD MATERIALS ENGINEERING 2516 01:36:06,560 --> 01:36:07,320 THAT WE'RE SEEING. 2517 01:36:07,320 --> 01:36:08,840 AND WE NEED TO FIGURE OUT HOW TO 2518 01:36:08,840 --> 01:36:11,960 DO THIS. 2519 01:36:11,960 --> 01:36:15,080 YOU'LL HEAR IN DAVE AND 2520 01:36:15,080 --> 01:36:15,840 STEPHANIE MORE ABOUT HOW WE 2521 01:36:15,840 --> 01:36:18,360 MIGHT BE ABLE TO EXTEND TO THOSE 2522 01:36:18,360 --> 01:36:19,440 DEMAINS BUT THAT'S ABSOLUTELY 2523 01:36:19,440 --> 01:36:20,040 CORRECT. 2524 01:36:20,040 --> 01:36:22,080 IF WE THINK WE COULD ON A 2525 01:36:22,080 --> 01:36:28,320 STRUCTURE THAT WE CAN COPY/PASTE 2526 01:36:28,320 --> 01:36:31,440 AND GIVE PEOPLE OPPORTUNITIES AT 2527 01:36:31,440 --> 01:36:33,360 RELATIVELY LOW RISK THEY CAN GET 2528 01:36:33,360 --> 01:36:33,760 INVOLVED WITH US. 2529 01:36:33,760 --> 01:36:35,920 >> THANK YOU. 2530 01:36:35,920 --> 01:36:39,120 >> THANKS. 2531 01:36:39,120 --> 01:36:40,200 >> THANK YOU. 2532 01:36:40,200 --> 01:36:41,680 ANY OTHER COMMENTS OR QUESTIONS 2533 01:36:41,680 --> 01:36:44,120 OR THOUGHTS FROM OUR COUNCIL 2534 01:36:44,120 --> 01:36:44,520 MEMBERS? 2535 01:36:44,520 --> 01:36:46,240 RANU, YOU RAISED USUAL HAND 2536 01:36:46,240 --> 01:36:47,000 AGAIN? 2537 01:36:47,000 --> 01:36:47,440 >> YEAH. 2538 01:36:47,440 --> 01:36:49,880 I RAISED MY HAND AGAIN. 2539 01:36:49,880 --> 01:36:51,840 AS WE'RE TALKING ABOUT THIS 2540 01:36:51,840 --> 01:36:53,560 FUNNEL MODEL, WE MIGHT ALSO WANT 2541 01:36:53,560 --> 01:36:56,280 TO THINK ABOUT SOME GUIDELINES 2542 01:36:56,280 --> 01:37:02,960 OF HOW ARE YOU BUDGETING. 2543 01:37:02,960 --> 01:37:05,160 YOUR BUDGET IS NOT 2544 01:37:05,160 --> 01:37:06,240 PRE-DETERMINED BECAUSE 2545 01:37:06,240 --> 01:37:07,360 MILESTONES HAVE BEEN MET, 2546 01:37:07,360 --> 01:37:08,760 WITHOUT -- YOU KNOW, SO MAYBE 2547 01:37:08,760 --> 01:37:10,480 THERE'S SOME HARD PROCESS TO BE 2548 01:37:10,480 --> 01:37:12,680 PUT ALONG WITH THAT OF 2549 01:37:12,680 --> 01:37:15,960 STRUCTURES TO BE SHARED IN 2550 01:37:15,960 --> 01:37:17,880 GUIDING THE SUBMITTERS OF HOW WE 2551 01:37:17,880 --> 01:37:23,720 SET UP BUDGET MODELS TO GO ALONG 2552 01:37:23,720 --> 01:37:24,600 WITH THAT FUNNEL. 2553 01:37:24,600 --> 01:37:27,040 >> YEAH, AND THIS NEW ONE WITH 2554 01:37:27,040 --> 01:37:28,840 NICHD AND MATERNAL HEALTH IS AN 2555 01:37:28,840 --> 01:37:30,200 EXPERIMENT BECAUSE AS YOU'VE 2556 01:37:30,200 --> 01:37:32,080 SEEN FROM OUR PREVIOUS RADx 2557 01:37:32,080 --> 01:37:35,480 FUNNEL BUDGETS THE FIRST WAS 2558 01:37:35,480 --> 01:37:38,280 $500 MILLION, SECOND WAS $100 2559 01:37:38,280 --> 01:37:38,520 MILLION. 2560 01:37:38,520 --> 01:37:41,200 THIS THIRD ONE IS $300 MILLION. 2561 01:37:41,200 --> 01:37:45,080 AND THIS FUNNEL IS $8 MILLION. 2562 01:37:45,080 --> 01:37:48,240 SO, QUITE DIFFERENT BUT IT'S 2563 01:37:48,240 --> 01:37:49,320 VERY, VERY FOCUSED. 2564 01:37:49,320 --> 01:37:51,760 AND IT'S TO A PARTICULAR DOMAIN. 2565 01:37:51,760 --> 01:37:52,600 ANOTHER THING THAT HELPED 2566 01:37:52,600 --> 01:37:54,600 SUPPORT THAT ALSO IF YOU LOOK AT 2567 01:37:54,600 --> 01:37:57,680 OUR POCTRN NETWORKS WE HAVE 2568 01:37:57,680 --> 01:37:59,040 SEVEN INSTITUTES IN THE 2569 01:37:59,040 --> 01:38:01,960 APPLICATION SPACE AREAS THAT ARE 2570 01:38:01,960 --> 01:38:03,720 DECORATED AROUND THESE CORE 2571 01:38:03,720 --> 01:38:04,280 CAPABILITIES. 2572 01:38:04,280 --> 01:38:06,320 AND SO THAT WILL HELP US HAVE 2573 01:38:06,320 --> 01:38:07,960 LESS EXPENSIVE FUNNELS. 2574 01:38:07,960 --> 01:38:09,960 IT'S AN ALTERNATIVE MECHANISM TO 2575 01:38:09,960 --> 01:38:13,560 OUR NORMAL, YOU KNOW, R01s AND 2576 01:38:13,560 --> 01:38:15,960 R21s, Ps, Us, SO FORTH BUT 2577 01:38:15,960 --> 01:38:18,280 IT IS CERTAINLY A POWERFUL ONE. 2578 01:38:18,280 --> 01:38:20,680 AND A KIND OF REALLY GOOD WAY TO 2579 01:38:20,680 --> 01:38:23,720 PLAY SMALL BALL IF YOU'RE A FAN 2580 01:38:23,720 --> 01:38:24,840 OF BASEBALL ANALOGIES, SPECIALLY 2581 01:38:24,840 --> 01:38:26,600 WITH AWARDS TO GET PEOPLE MONEY 2582 01:38:26,600 --> 01:38:29,440 QUICKLY AND GET ON BASE AND GET 2583 01:38:29,440 --> 01:38:29,840 MOVING. 2584 01:38:29,840 --> 01:38:33,360 AND THEN FOLLOW THAT UP WITH 2585 01:38:33,360 --> 01:38:43,000 LARGER LONG-TERM GRANTS. 2586 01:38:43,000 --> 01:38:44,800 >> TEJAL? 2587 01:38:44,800 --> 01:38:45,680 >> ALL THIS ECHO AGAIN. 2588 01:38:45,680 --> 01:38:47,600 MY THANKS FOR ALL THE IMPRESSIVE 2589 01:38:47,600 --> 01:38:50,680 WORK YOU'RE DOING. 2590 01:38:50,680 --> 01:38:51,760 IT'S TRULY REMARKABLE, REALLY, 2591 01:38:51,760 --> 01:38:53,200 THE PROGRESS THAT YOU'VE MADE. 2592 01:38:53,200 --> 01:38:55,680 ONE OF THE THINGS OR POINTS I 2593 01:38:55,680 --> 01:38:58,080 WANTED TO MAKE, I THINK THIS IS 2594 01:38:58,080 --> 01:39:02,440 PARTLY SOMETHING THAT WE CAN DO 2595 01:39:02,440 --> 01:39:05,280 IN COUNCIL, IS TO ALSO EDUCATE 2596 01:39:05,280 --> 01:39:10,760 THOSE ON THE OUTSIDE THAT THESE 2597 01:39:10,760 --> 01:39:14,120 NEW MECHANISMS ARE ACTUALLY, YOU 2598 01:39:14,120 --> 01:39:15,880 KNOW, QUITE -- THEY ARE, YOU 2599 01:39:15,880 --> 01:39:18,440 KNOW, QUITE IMPORTANT AND 2600 01:39:18,440 --> 01:39:21,760 ACTUALLY OF HIGH VALUE, AND THAT 2601 01:39:21,760 --> 01:39:24,320 THEY ARE PEER REVIEWED IN THE 2602 01:39:24,320 --> 01:39:26,280 SAME WAY THAT SOME OTHER 2603 01:39:26,280 --> 01:39:27,080 CONVENTIONAL MECHANISMS ARE. 2604 01:39:27,080 --> 01:39:29,560 THE REASON I SAY THAT, AS 2605 01:39:29,560 --> 01:39:31,400 SOMEBODY REVIEWING AT LEAST FOR 2606 01:39:31,400 --> 01:39:33,400 THE EARLY FACULTY THAT ARE 2607 01:39:33,400 --> 01:39:35,560 COMING DOWN THE PIPELINE AND 2608 01:39:35,560 --> 01:39:36,880 PROMOTIONS AND TENURE, AS THEY 2609 01:39:36,880 --> 01:39:40,920 START TO SHOW THESE TYPES OF 2610 01:39:40,920 --> 01:39:42,800 MECHANISMS, I'VE HAD TO ADVOCATE 2611 01:39:42,800 --> 01:39:44,440 THAT THESE ARE REALLY IMPORTANT, 2612 01:39:44,440 --> 01:39:47,520 THAT THEY ARE REALLY A MARK OF 2613 01:39:47,520 --> 01:39:48,800 INNOVATIVENESS AND, YOU KNOW, 2614 01:39:48,800 --> 01:39:51,000 REALLY PUTTING THEM IN THE TRACK 2615 01:39:51,000 --> 01:39:52,400 TO ACHIEVE THESE LARGER GRANTS 2616 01:39:52,400 --> 01:39:53,960 BUT THIS IS SOMETHING THAT I 2617 01:39:53,960 --> 01:39:56,280 THINK THE COMMUNITY AS A WHOLE 2618 01:39:56,280 --> 01:39:58,600 MIGHT WANT TO TAKE ON AND REALLY 2619 01:39:58,600 --> 01:39:59,880 SHOWCASE THAT THESE ARE 2620 01:39:59,880 --> 01:40:03,680 VALUABLE. 2621 01:40:03,680 --> 01:40:05,080 >> YEAH, TEJAL, YOU JUST 2622 01:40:05,080 --> 01:40:06,920 REALLY -- YOU CALLED OUT THE 2623 01:40:06,920 --> 01:40:08,360 CULTURAL CHALLENGES WHICH WE ALL 2624 01:40:08,360 --> 01:40:10,080 HAVE FACED THROUGH OUR CAREERS, 2625 01:40:10,080 --> 01:40:12,680 YOU KNOW, FIRST IT WAS IS 2626 01:40:12,680 --> 01:40:13,720 TEAM-BASED RESEARCH OKAY, HOW DO 2627 01:40:13,720 --> 01:40:17,000 YOU GET CREDIT FOR PEOPLE WHO DO 2628 01:40:17,000 --> 01:40:18,320 TECHNOLOGY INNOVATION, AND WE'LL 2629 01:40:18,320 --> 01:40:21,920 SEE A CONTINUED EVOLUTION OF 2630 01:40:21,920 --> 01:40:22,880 MECHANISMS, CERTAINLY THE R01 2631 01:40:22,880 --> 01:40:25,000 STANDARD IS STUCK IN OUR HEADS 2632 01:40:25,000 --> 01:40:26,840 AND PROMOTION AND TENURE 2633 01:40:26,840 --> 01:40:29,680 COMMITTEE HEADS, AS BEING THE 2634 01:40:29,680 --> 01:40:32,200 STANDARD BEARER, BUT IN A 2635 01:40:32,200 --> 01:40:34,720 DIFFERENT DOMAIN OF ACCELERATED 2636 01:40:34,720 --> 01:40:36,360 TECHNOLOGY DEVELOPMENT THESE 2637 01:40:36,360 --> 01:40:39,840 OTHER APPROACHES NEED TO ACHIEVE 2638 01:40:39,840 --> 01:40:44,120 A KIND OF GRAVITAS FOR THE 2639 01:40:44,120 --> 01:40:45,040 INVESTIGATORS, AND THAT'S GOING 2640 01:40:45,040 --> 01:40:46,240 TO BE A GROUP AND COMMUNITY 2641 01:40:46,240 --> 01:40:48,840 PROBLEM FOR US TO ADDRESS FOR 2642 01:40:48,840 --> 01:40:49,480 SURE. 2643 01:40:49,480 --> 01:40:50,920 BUT YOU GUYS ARE IN A GOOD 2644 01:40:50,920 --> 01:40:52,280 POSITION TO DO THAT, TO HELP 2645 01:40:52,280 --> 01:40:54,840 WITH THAT. 2646 01:40:54,840 --> 01:41:00,600 2647 01:41:00,600 --> 01:41:01,280 >> DAN? 2648 01:41:01,280 --> 01:41:03,000 >> YES, SO COMING IN NEW AS I 2649 01:41:03,000 --> 01:41:06,400 AM, FIRST OF ALL I ALSO WANT TO 2650 01:41:06,400 --> 01:41:08,600 ECHO CONGRATULATIONS ON A 2651 01:41:08,600 --> 01:41:10,080 REMARKABLE RECORD OF ACTIVITIES 2652 01:41:10,080 --> 01:41:11,760 AND IMPACT, AND I'LL BE HONORED 2653 01:41:11,760 --> 01:41:13,240 TO JOIN THIS DISTINGUISHED 2654 01:41:13,240 --> 01:41:14,680 COMMUNITY OF COUNSELORS. 2655 01:41:14,680 --> 01:41:16,560 AS I WAS LISTENING, I WAS 2656 01:41:16,560 --> 01:41:20,240 REFLECTING ON THE THEME OF 2657 01:41:20,240 --> 01:41:21,560 ACCESSIBILITY AND ALSO THE 2658 01:41:21,560 --> 01:41:23,000 QUESTION ABOUT ONGOING ROLE OF 2659 01:41:23,000 --> 01:41:23,880 IMAGING. 2660 01:41:23,880 --> 01:41:27,480 I GUESS I JUST WANTED TO NOTE 2661 01:41:27,480 --> 01:41:30,440 THAT THERE'S BEEN A REALLY 2662 01:41:30,440 --> 01:41:33,960 SERIOUS MOVE TOWARDS ADDRESSING 2663 01:41:33,960 --> 01:41:35,440 ACCESSIBILITY AND HEALTH 2664 01:41:35,440 --> 01:41:37,240 DISPARITY IN THE FIELD OF 2665 01:41:37,240 --> 01:41:40,680 IMAGING EVEN FOR DEVICES LIKE 2666 01:41:40,680 --> 01:41:43,000 MRI, CT, PET SCANNERS, 2667 01:41:43,000 --> 01:41:43,880 TRADITIONALLY BIG AND EXPENSIVE 2668 01:41:43,880 --> 01:41:45,000 AND RESOURCE HUNGRY. 2669 01:41:45,000 --> 01:41:47,880 SO IT'S NOT JUST WEARABLES AND 2670 01:41:47,880 --> 01:41:49,040 POINT OF CARE DEVICES, NOW 2671 01:41:49,040 --> 01:41:52,480 THERE'S MUCH MORE OF AN INTEREST 2672 01:41:52,480 --> 01:41:54,760 I THINK WORLDWIDE IN POINT OF 2673 01:41:54,760 --> 01:41:56,520 CARE IMAGING, AND I THINK THIS 2674 01:41:56,520 --> 01:41:59,080 IS ONE AREA THAT NIBIB COULD 2675 01:41:59,080 --> 01:42:00,600 POTENTIALLY PLAY A LEADING ROLE 2676 01:42:00,600 --> 01:42:03,120 AND THAT WOULD SOME WAYS CONNECT 2677 01:42:03,120 --> 01:42:06,000 SOME OF ITS DISPARATE AREAS OF 2678 01:42:06,000 --> 01:42:08,680 INTEREST AND FOCUS. 2679 01:42:08,680 --> 01:42:10,440 >> YEAH, ABSOLUTELY AGREE. 2680 01:42:10,440 --> 01:42:11,520 AND BOTH THE TECHNOLOGIES GOING 2681 01:42:11,520 --> 01:42:12,720 TO POINT OF CARE AND WE DO 2682 01:42:12,720 --> 01:42:15,080 SUPPORT A FEW OF THOSE, YOU 2683 01:42:15,080 --> 01:42:17,960 KNOW, LIKE HEAD ONLY MRIs, SO 2684 01:42:17,960 --> 01:42:21,040 FORTH, BUT ALSO THE LINKAGE 2685 01:42:21,040 --> 01:42:22,560 BETWEEN THE SMALL PHYSICS 2686 01:42:22,560 --> 01:42:27,040 TECHNOLOGY WHICH IS ON OR IN THE 2687 01:42:27,040 --> 01:42:27,680 PATIENT, AND THE INFORMATION 2688 01:42:27,680 --> 01:42:29,720 GENERATION THAT MAY BE 2689 01:42:29,720 --> 01:42:30,320 ACTIONABLE THAT SAYS, OKAY, 2690 01:42:30,320 --> 01:42:33,280 PATIENT, GO TO THE BIG PHYSICS 2691 01:42:33,280 --> 01:42:34,360 NOW. 2692 01:42:34,360 --> 01:42:35,880 SO THAT'S ABSOLUTE -- THERE IS 2693 01:42:35,880 --> 01:42:39,280 A -- WE NEED TO DO BETTER WITH 2694 01:42:39,280 --> 01:42:39,440 THAT. 2695 01:42:39,440 --> 01:42:41,680 I THINK PART OF IT IS SOME OF 2696 01:42:41,680 --> 01:42:43,680 THE BIAS OF THE MEDICAL 2697 01:42:43,680 --> 01:42:45,960 COMMUNITY THAT IS NOT QUITE 2698 01:42:45,960 --> 01:42:47,920 READY TO SORT OF CONNECT ALL 2699 01:42:47,920 --> 01:42:49,800 THOSE PIECES BUT THE RESEARCH 2700 01:42:49,800 --> 01:42:52,440 COMMUNITY IS OUT THERE, MAKING A 2701 01:42:52,440 --> 01:42:54,480 HUGE EFFORT, AND ALL OF US IS 2702 01:42:54,480 --> 01:42:59,040 ONE OF THOSE EXAMPLES WHERE 2703 01:42:59,040 --> 01:42:59,840 WE'RE HOPING TO IMPACT, I THINK 2704 01:42:59,840 --> 01:43:02,560 WE'RE ON THE VERGE OF GETTING 2705 01:43:02,560 --> 01:43:05,960 CLOSE TO WHERE "ALL OF US" MAY 2706 01:43:05,960 --> 01:43:07,360 INTRODUCE IMAGING INTO ITS 2707 01:43:07,360 --> 01:43:07,600 PROGRAM. 2708 01:43:07,600 --> 01:43:09,880 SO WE'RE WORKING ON THAT. 2709 01:43:09,880 --> 01:43:12,720 THAT WILL BE FOR FUTURE 2710 01:43:12,720 --> 01:43:13,880 COUNCILS. 2711 01:43:13,880 --> 01:43:16,320 >> MAYBE I CAN JUST JUMP IN TO 2712 01:43:16,320 --> 01:43:18,960 REINFORCE THAT POINT. 2713 01:43:18,960 --> 01:43:21,080 I HEARD AN INTERESTING NUMBER IN 2714 01:43:21,080 --> 01:43:23,320 OUR INSTITUTION, APPARENTLY THEY 2715 01:43:23,320 --> 01:43:25,880 ARE PLANNING THAT 10% OF THE 2716 01:43:25,880 --> 01:43:28,440 HOSPITALIZED PATIENTS WILL BE 2717 01:43:28,440 --> 01:43:30,280 HOME HOSPITAL PATIENTS. 2718 01:43:30,280 --> 01:43:32,480 AND OF COURSE, THIS IS EXACTLY 2719 01:43:32,480 --> 01:43:34,840 AS DAN WAS SUGGESTING, AN 2720 01:43:34,840 --> 01:43:36,960 OPPORTUNITY, YOU KNOW, BOTH FOR, 2721 01:43:36,960 --> 01:43:38,520 YOU KNOW, MONITORING AT HOME BUT 2722 01:43:38,520 --> 01:43:39,960 ALSO HOW WE CAN THINK ABOUT 2723 01:43:39,960 --> 01:43:41,360 GETTING THE KIND OF DATA THAT 2724 01:43:41,360 --> 01:43:47,840 WE'RE USED TO GETTING IN A 2725 01:43:47,840 --> 01:43:48,520 HOSPITAL SETTING, PORTABLE AND 2726 01:43:48,520 --> 01:43:50,880 HOME HEALTH SETTINGS, ET CETERA, 2727 01:43:50,880 --> 01:43:52,280 A REMARKABLE NUMBER, IT'S A LOT 2728 01:43:52,280 --> 01:43:54,480 OF PATIENTS, BUT THAT IS THE 2729 01:43:54,480 --> 01:43:57,880 DIRECTION I'M SURE ALL 2730 01:43:57,880 --> 01:43:59,600 INSTITUTIONS ARE MOVING TOWARDS. 2731 01:43:59,600 --> 01:44:00,240 >> ABSOLUTELY. 2732 01:44:00,240 --> 01:44:02,680 I MEAN, WE NEED TO DO BETTER 2733 01:44:02,680 --> 01:44:03,960 WITH QUANTITATIVE METROLOGY IN 2734 01:44:03,960 --> 01:44:04,840 THE HOME. 2735 01:44:04,840 --> 01:44:06,280 WE'RE ALL -- WE'VE ALL BEEN 2736 01:44:06,280 --> 01:44:07,880 WORKING IN THESE AREAS. 2737 01:44:07,880 --> 01:44:10,720 WE KNOW SIGNALS ARE AVAILABLE 2738 01:44:10,720 --> 01:44:12,440 AND TECHNOLOGIES ARE DOABLE. 2739 01:44:12,440 --> 01:44:14,480 AND WE'VE SEEN THE EXPLOSION OF 2740 01:44:14,480 --> 01:44:17,000 IT WITH IN VITRO DIAGNOSTICS. 2741 01:44:17,000 --> 01:44:20,080 I'M STILL ASTOUNDED BY THOSE 2742 01:44:20,080 --> 01:44:22,280 NUMBERS, I CAN BARELY SAY THEM, 2743 01:44:22,280 --> 01:44:25,760 ONE BILLION IN VITRO TESTS 2744 01:44:25,760 --> 01:44:26,240 DISTRIBUTED. 2745 01:44:26,240 --> 01:44:27,720 A LOT OF PRESS REPORTS THAT IN 2746 01:44:27,720 --> 01:44:29,400 VITRO DIAGNOSTICS DON'T WORK 2747 01:44:29,400 --> 01:44:31,280 THAT WELL BUT THEY ACTUALLY WORK 2748 01:44:31,280 --> 01:44:31,880 REALLY WELL. 2749 01:44:31,880 --> 01:44:34,520 IT'S JUST THAT WHEN YOU HAVE A 2750 01:44:34,520 --> 01:44:37,080 BILLION OF THEM OUT, THAT ARE 2751 01:44:37,080 --> 01:44:38,560 RELEASED, THERE ARE GOING TO BE 2752 01:44:38,560 --> 01:44:40,880 MAYBE 100 MILLION PEOPLE 2753 01:44:40,880 --> 01:44:41,280 UNHAPPY. 2754 01:44:41,280 --> 01:44:43,160 YOU'LL HEAR ABOUT THEM. 2755 01:44:43,160 --> 01:44:45,120 AND IT'S JUST A COMPLETE 2756 01:44:45,120 --> 01:44:46,200 PARADIGM SHIFT, STILL HARD FOR 2757 01:44:46,200 --> 01:44:48,360 ME TO GET MY HEAD AROUND BUT 2758 01:44:48,360 --> 01:44:52,000 SLIGHTLY -- ABSOLUTELY THIS HAS 2759 01:44:52,000 --> 01:44:53,560 TO BE COMING FROM ALL DIRECTIONS 2760 01:44:53,560 --> 01:44:56,800 IN THE COMMUNITY, THE BIG AND 2761 01:44:56,800 --> 01:44:59,080 LITTLE PHYSICS. 2762 01:44:59,080 --> 01:45:00,280 >> THANK YOU. 2763 01:45:00,280 --> 01:45:02,120 JOYCE AND ZANE AND THEN BRUCE 2764 01:45:02,120 --> 01:45:04,120 WILL WANT TO THINK ABOUT MAYBE 2765 01:45:04,120 --> 01:45:05,880 SUMMING UP. 2766 01:45:05,880 --> 01:45:07,640 WE'RE RUNNING OVER ON THIS 2767 01:45:07,640 --> 01:45:07,880 SEGMENT. 2768 01:45:07,880 --> 01:45:08,480 GREAT DISCUSSION. 2769 01:45:08,480 --> 01:45:09,200 THANK YOU. 2770 01:45:09,200 --> 01:45:11,760 >> YES, I JUST WANT TO ALSO ECHO 2771 01:45:11,760 --> 01:45:14,080 WHAT EVERYBODY SAID. 2772 01:45:14,080 --> 01:45:15,800 THIS IS TREMENDOUS, MY FIRST 2773 01:45:15,800 --> 01:45:17,960 TIME HERE, I ECHO WHAT DAN SAID, 2774 01:45:17,960 --> 01:45:19,560 I'M EXCITED TO JOIN COUNCIL. 2775 01:45:19,560 --> 01:45:22,360 I WANTED TO SAY I THINK IT'S 2776 01:45:22,360 --> 01:45:23,680 FANTASTIC WITH THE PARTNERSHIP 2777 01:45:23,680 --> 01:45:26,440 WITH NICHD AND FUNNEL MODEL, I 2778 01:45:26,440 --> 01:45:27,840 THINK THAT'S SO WONDERFUL DOING 2779 01:45:27,840 --> 01:45:29,240 MATERNAL HEALTH. 2780 01:45:29,240 --> 01:45:30,800 I THINK IT'S REALLY VERY 2781 01:45:30,800 --> 01:45:34,080 UNDERFUNDED AND I THINK THAT'S 2782 01:45:34,080 --> 01:45:34,760 FANTASTIC. 2783 01:45:34,760 --> 01:45:36,160 MY COMMENT IS ACTUALLY FOR JILL. 2784 01:45:36,160 --> 01:45:40,400 I THINK THAT WAS TREMENDOUS WHAT 2785 01:45:40,400 --> 01:45:41,840 YOU'VE DONE WITH ACCESSIBILITY 2786 01:45:41,840 --> 01:45:43,680 AND HAVING THOSE GUIDELINES AND 2787 01:45:43,680 --> 01:45:45,880 YOU MENTIONED HAVING THEM REALLY 2788 01:45:45,880 --> 01:45:47,080 OPENLY AVAILABLE SO I MYSELF 2789 01:45:47,080 --> 01:45:49,280 TEACH A DESIGN COURSE TO JUNIORS 2790 01:45:49,280 --> 01:45:52,360 AND SENIORS I THINK IT WOULD BE 2791 01:45:52,360 --> 01:45:53,880 WONDERFUL TO HAVE THAT MATERIAL 2792 01:45:53,880 --> 01:45:56,760 AVAILABLE FOR EDUCATION AND SO A 2793 01:45:56,760 --> 01:45:58,880 LOT OF, AS YOU KNOW, IN THE 2794 01:45:58,880 --> 01:46:00,320 DEBUT CHALLENGES, I THINK IT 2795 01:46:00,320 --> 01:46:02,760 WOULD BE GREAT TO EMBED THAT 2796 01:46:02,760 --> 01:46:03,880 INTO THE CURRICULUM SO ANY KIND 2797 01:46:03,880 --> 01:46:05,480 OF WAY YOU CAN SHARE THAT 2798 01:46:05,480 --> 01:46:07,360 INFORMATION, A WAY WE CAN ADOPT 2799 01:46:07,360 --> 01:46:08,680 IT INTO OUR CURRICULUM THAT 2800 01:46:08,680 --> 01:46:11,840 WOULD BE REALLY NICE. 2801 01:46:11,840 --> 01:46:13,760 >> THAT'S EXCITING, JOYCE. 2802 01:46:13,760 --> 01:46:15,680 THAT'S GREAT TO HEAR. 2803 01:46:15,680 --> 01:46:18,880 SO, WHAT WE'D LIKE TO DO IS 2804 01:46:18,880 --> 01:46:19,600 RELEASE THE INFORMATION IN 2805 01:46:19,600 --> 01:46:22,840 STAGES, SORT OF AS DIFFERENT 2806 01:46:22,840 --> 01:46:24,000 ASPECTS MATURE LIKE THE 2807 01:46:24,000 --> 01:46:25,960 INSTRUCTIONS FOR USE WILL BE 2808 01:46:25,960 --> 01:46:27,880 COMING ONLINE PRETTY QUICKLY. 2809 01:46:27,880 --> 01:46:30,320 AND WORK WITH THE U.S. ACCESS 2810 01:46:30,320 --> 01:46:33,240 BOARD TO KEEP PUTTING THINGS OUT 2811 01:46:33,240 --> 01:46:34,600 AS THEY ARE READY. 2812 01:46:34,600 --> 01:46:37,040 WE'VE GOT SOME URGENCY BECAUSE 2813 01:46:37,040 --> 01:46:40,120 WE'D LIKE THEM TO BE AVAILABLE 2814 01:46:40,120 --> 01:46:42,120 FOR NEW SOLICITATIONS, ASKING 2815 01:46:42,120 --> 01:46:43,320 FOR PEOPLE TO ADDRESS 2816 01:46:43,320 --> 01:46:44,120 ACCESSIBILITY. 2817 01:46:44,120 --> 01:46:45,880 WE'RE ON A PRETTY FAST TRACK I 2818 01:46:45,880 --> 01:46:48,360 THINK, TRYING HARD TO GET SOME 2819 01:46:48,360 --> 01:46:49,920 STUFF AVAILABLE FOR THIS FALL, 2820 01:46:49,920 --> 01:46:53,440 FOR THE FALL CLASSES. 2821 01:46:53,440 --> 01:46:54,720 WHICH I HADN'T APPRECIATED. 2822 01:46:54,720 --> 01:46:58,680 THANK YOU, THAT'S A GREAT IDEA. 2823 01:46:58,680 --> 01:47:01,720 >> THANK YOU, JOYCE. 2824 01:47:01,720 --> 01:47:02,360 ZANE? 2825 01:47:02,360 --> 01:47:02,960 >> THANKS, EVERYBODY. 2826 01:47:02,960 --> 01:47:04,760 I'M GOING TO ADD TO THE 2827 01:47:04,760 --> 01:47:06,520 CONVERSATION ABOUT THE DIVERSITY 2828 01:47:06,520 --> 01:47:08,320 BECAUSE I THINK THIS COMMUNITY 2829 01:47:08,320 --> 01:47:09,920 HAS A GREAT OPPORTUNITY RIGHT 2830 01:47:09,920 --> 01:47:12,080 NOW TO REALLY CONTRIBUTE TO 2831 01:47:12,080 --> 01:47:13,200 PERSONALIZED MEDICINE. 2832 01:47:13,200 --> 01:47:15,160 THE KEY IS EVERYTHING'S MOVING 2833 01:47:15,160 --> 01:47:17,280 TOWARDS YOU AS THE INDIVIDUAL 2834 01:47:17,280 --> 01:47:19,000 BEING THE DIVERSIFIED OBJECT IN 2835 01:47:19,000 --> 01:47:20,880 YOUR OWN PERSONAL HEALTH CARE. 2836 01:47:20,880 --> 01:47:23,120 AND RIGHT NOW THERE'S A LOT NOT 2837 01:47:23,120 --> 01:47:25,120 UNDERSTOOD ABOUT EVEN THE 2838 01:47:25,120 --> 01:47:27,280 UNDERLYING FACTORS THAT AFFECT 2839 01:47:27,280 --> 01:47:28,440 THAT. 2840 01:47:28,440 --> 01:47:33,880 PRIME EXAMPLE IS THE PULSE OXY 2841 01:47:33,880 --> 01:47:35,840 METER, NO LATERAL AGREEMENT IT'S 2842 01:47:35,840 --> 01:47:36,720 THE PROBLEM AND NOT UNILATERAL 2843 01:47:36,720 --> 01:47:38,040 AGREEMENT WHETHER COLOR AND SKIN 2844 01:47:38,040 --> 01:47:40,760 COLOR IS THE PRIMARY FACTOR IN 2845 01:47:40,760 --> 01:47:43,920 THAT DIFFERENTIATING FACTOR IN 2846 01:47:43,920 --> 01:47:44,880 THESE STUDIES. 2847 01:47:44,880 --> 01:47:47,400 THE PROBLEM IS THERE'S A LOT OF 2848 01:47:47,400 --> 01:47:48,280 FACTORS THAT COULD POTENTIALLY 2849 01:47:48,280 --> 01:47:50,280 BE CONTRIBUTING AND WE DON'T 2850 01:47:50,280 --> 01:47:51,280 UNDERSTAND THEM. 2851 01:47:51,280 --> 01:47:54,080 THERE'S A GREAT OPPORTUNITY TO 2852 01:47:54,080 --> 01:47:56,120 USE A.I. TO LOOK AT A VARIETY OF 2853 01:47:56,120 --> 01:47:57,200 FACTORS TO HELP UNDERSTAND HOW 2854 01:47:57,200 --> 01:47:59,760 WE'RE GOING TO TAKE THIS 2855 01:47:59,760 --> 01:48:06,520 MEDICINE AND AS DAVE SAID 2856 01:48:06,520 --> 01:48:08,160 EARLIER FROM THE HOSPITAL TO THE 2857 01:48:08,160 --> 01:48:09,120 PATIENT AT HOME, GETTING BETTER 2858 01:48:09,120 --> 01:48:10,760 HEALTH CARE FOR PATIENTS AT HOME 2859 01:48:10,760 --> 01:48:12,640 AS OPPOSED TO IN A HOSPITAL 2860 01:48:12,640 --> 01:48:16,000 WHERE A MEDICAL PHYSICIAN IS 2861 01:48:16,000 --> 01:48:16,680 THERE. 2862 01:48:16,680 --> 01:48:17,080 >> THANKS, ZANE. 2863 01:48:17,080 --> 01:48:18,080 I'M GOING TO TURN THAT BACK 2864 01:48:18,080 --> 01:48:20,880 AROUND TO ALL OF YOU, MY 2865 01:48:20,880 --> 01:48:25,080 COLLEAGUES, BECAUSE I AM STRUCK, 2866 01:48:25,080 --> 01:48:30,600 I'VE BEEN OVERWHELMED BY THE 2867 01:48:30,600 --> 01:48:35,200 ABSENCE OF EXPERTISE OUR 2868 01:48:35,200 --> 01:48:36,400 COMMUNITY BRINGS ACROSS 2869 01:48:36,400 --> 01:48:37,560 GOVERNMENT, MAJOR INSTITUTIONS 2870 01:48:37,560 --> 01:48:37,960 ACROSS GOVERNMENT. 2871 01:48:37,960 --> 01:48:40,880 THIS HAS ALL BECOME VERY OBVIOUS 2872 01:48:40,880 --> 01:48:45,240 AS WE'VE PUSHED HARD INTO OUR 2873 01:48:45,240 --> 01:48:45,680 COVID RESPONSE. 2874 01:48:45,680 --> 01:48:49,560 AND EVEN IN THE NIH, YOU KNOW, 2875 01:48:49,560 --> 01:48:51,000 WE'RE PRETTY UNIQUE BECAUSE I 2876 01:48:51,000 --> 01:48:53,080 THINK PEOPLE DO A FINE JOB OF 2877 01:48:53,080 --> 01:48:55,560 IDENTIFYING MANY OF THESE 2878 01:48:55,560 --> 01:48:58,480 PROBLEMS BUT TO HAVE THE SORT OF 2879 01:48:58,480 --> 01:49:00,320 TECHNOLOGY FOUNDATION AND 2880 01:49:00,320 --> 01:49:02,440 UNDERSTANDING OF DETAILS OF HOW 2881 01:49:02,440 --> 01:49:05,160 STUFF WORKS IS REALLY LACKING, 2882 01:49:05,160 --> 01:49:06,760 ESPECIALLY AS WE MOVE INTO 2883 01:49:06,760 --> 01:49:10,680 BROADER AREAS OF MEDICINE, 2884 01:49:10,680 --> 01:49:13,160 PUBLIC HEALTH, EPIDEMIOLOGY. 2885 01:49:13,160 --> 01:49:14,280 YOU PROBABLY HEARD ME SAY THIS 2886 01:49:14,280 --> 01:49:15,880 BEFORE, THIS IS MY PLEA. 2887 01:49:15,880 --> 01:49:18,720 WE'RE HOPING TO BE ABLE TO WORK 2888 01:49:18,720 --> 01:49:22,440 WITH NSF ON THIS TO EXPAND 2889 01:49:22,440 --> 01:49:23,320 STRANGE OPPORTUNITIES FOR 2890 01:49:23,320 --> 01:49:24,240 BIOMEDICAL ENGINEERS TO HAVE 2891 01:49:24,240 --> 01:49:27,720 CAREER CHOICES TO COME INTO 2892 01:49:27,720 --> 01:49:28,440 GOVERNMENT. 2893 01:49:28,440 --> 01:49:32,200 FDA HAS GOT FANTASTIC COLLECTION 2894 01:49:32,200 --> 01:49:33,760 OF ENGINEERS AND PHYSICAL 2895 01:49:33,760 --> 01:49:35,440 SCIENTISTS, BUT WE NEED MORE AND 2896 01:49:35,440 --> 01:49:37,840 WE NEED THEM IN OTHER AGENCIES 2897 01:49:37,840 --> 01:49:39,480 SO THEY CAN SPEAK TO FOLKS 2898 01:49:39,480 --> 01:49:41,880 BECAUSE A LOT OF THE ONES IN THE 2899 01:49:41,880 --> 01:49:43,080 FDA ARE NOT NECESSARILY 2900 01:49:43,080 --> 01:49:44,080 INFLUENCING ALL ASPECTS OF 2901 01:49:44,080 --> 01:49:47,000 WHAT'S GOING ON IN THE FDA. 2902 01:49:47,000 --> 01:49:49,680 ESPECIALLY AT THE POLICY LEVEL. 2903 01:49:49,680 --> 01:49:53,560 AND AS YOU ALL KNOW, YOU'VE GOT 2904 01:49:53,560 --> 01:49:54,600 TO HAVE THAT DETAILED 2905 01:49:54,600 --> 01:49:56,480 UNDERSTANDING OF HOW STUFF WORKS 2906 01:49:56,480 --> 01:49:57,840 TO REALLY MAKE A DIFFERENCE AND 2907 01:49:57,840 --> 01:49:58,160 IMPACT. 2908 01:49:58,160 --> 01:50:01,440 I SEE WHAT WE'VE BEEN ABLE TO DO 2909 01:50:01,440 --> 01:50:03,080 IN THE PANDEMIC, AS A COMMUNITY 2910 01:50:03,080 --> 01:50:04,280 EXPERTISE KIND OF THING. 2911 01:50:04,280 --> 01:50:10,680 AND WE WANT TO EXPAND THAT AS 2912 01:50:10,680 --> 01:50:12,720 YOU POINT OUT, ZANE, IN ALL 2913 01:50:12,720 --> 01:50:19,400 ASPECTS OF PERSONALIZED MEDICINE 2914 01:50:19,400 --> 01:50:20,280 AND HEALTH. 2915 01:50:20,280 --> 01:50:27,040 >> THANK YOU FOR EXCELLENT INPUT 2916 01:50:27,040 --> 01:50:28,080 AND DISCUSSION. 2917 01:50:28,080 --> 01:50:29,080 ANYTHING BEFORE WE TRANSITION TO 2918 01:50:29,080 --> 01:50:31,280 THE NEXT PRESENTATION. 2919 01:50:31,280 --> 01:50:33,680 >> WE TEED UP THE NEXT ONE. 2920 01:50:33,680 --> 01:50:38,000 OH MY GOSH. 2921 01:50:38,000 --> 01:50:39,520 DATA AND SELF-MATERIALS, LET'S 2922 01:50:39,520 --> 01:50:40,160 JUST GET GOING. 2923 01:50:40,160 --> 01:50:40,960 >> SUPER. 2924 01:50:40,960 --> 01:50:43,680 THANK YOU SO MUCH. 2925 01:50:43,680 --> 01:50:47,400 NEXT ITEM IS PRESENTATION FROM 2926 01:50:47,400 --> 01:50:50,960 OUR COLLEAGUE DR. QUI DUAN ON 2927 01:50:50,960 --> 01:50:51,840 DATA MANAGEMENT AND SHARING 2928 01:50:51,840 --> 01:50:53,440 POLICY, THOSE OF YOU WHO HAVE 2929 01:50:53,440 --> 01:50:57,880 BEEN NO DOUBT ATEN I ATTENTIVE 2930 01:50:57,880 --> 01:51:00,160 TO NIH NEWS ARE AWARE OF THE BIG 2931 01:51:00,160 --> 01:51:06,480 THING COMING DOWN THE PIKE, AND 2932 01:51:06,480 --> 01:51:08,080 DELIGHTED TO HAVE QI GIVE AN 2933 01:51:08,080 --> 01:51:08,640 UPDATE. 2934 01:51:08,640 --> 01:51:10,000 THANK YOU, QI. 2935 01:51:10,000 --> 01:51:13,600 >> THANK YOU FOR THE 2936 01:51:13,600 --> 01:51:13,920 INTRODUCTION. 2937 01:51:13,920 --> 01:51:15,800 TODAY I WILL GIVE A BRIEF UPDATE 2938 01:51:15,800 --> 01:51:18,200 ON THE NIH DATA MANAGEMENT AND 2939 01:51:18,200 --> 01:51:24,080 SHARING POLICY AS WELL AS 2940 01:51:24,080 --> 01:51:27,000 CORRESPONDING UPDATE AND FOLLOW 2941 01:51:27,000 --> 01:51:30,880 THE PRESENTATION BY DISCUSSION. 2942 01:51:30,880 --> 01:51:32,400 TO CLARIFY THE DISCUSSION TODAY 2943 01:51:32,400 --> 01:51:34,680 IT'S ONLY FOCUSING ON DATA 2944 01:51:34,680 --> 01:51:36,240 MANAGEMENT AND SHARING PART. 2945 01:51:36,240 --> 01:51:39,760 THERE ARE OTHER PARTS IN THE 2946 01:51:39,760 --> 01:51:42,600 RESEARCH SHARING PLAN, JUST LIKE 2947 01:51:42,600 --> 01:51:46,080 OTHER SOFTWARE SHARING OR 2948 01:51:46,080 --> 01:51:47,080 TECHNOLOGY SHARING, NOT COVERED 2949 01:51:47,080 --> 01:51:48,040 BY TODAY'S DISCUSSION. 2950 01:51:48,040 --> 01:51:57,360 WE MAY TOUCH A LITTLE BIT ON THE 2951 01:51:57,360 --> 01:52:00,040 PUBLICATION SHARING AS NEEDED. 2952 01:52:00,040 --> 01:52:03,080 A BRIEF HISTORY OF THE DATA 2953 01:52:03,080 --> 01:52:03,960 SHARING POLICY, CURRENT DATA 2954 01:52:03,960 --> 01:52:08,520 SHARING POLICY CAME IN EFFECT IN 2955 01:52:08,520 --> 01:52:08,720 2003. 2956 01:52:08,720 --> 01:52:11,440 IN 2015 NIH STARTED ITERATIVE 2957 01:52:11,440 --> 01:52:13,280 NEW POLICY DEVELOPMENT PROCESS, 2958 01:52:13,280 --> 01:52:16,560 NEW DATA MANAGEMENT SHARING 2959 01:52:16,560 --> 01:52:18,840 POLICY WAS RELEASED IN 2020, 2960 01:52:18,840 --> 01:52:21,560 WHICH WILL COME TO EFFECT IN 2961 01:52:21,560 --> 01:52:22,240 2023. 2962 01:52:22,240 --> 01:52:28,120 THE GOAL OF THE POLICY IS TO 2963 01:52:28,120 --> 01:52:28,680 ADVANCE RIGOROUS AND 2964 01:52:28,680 --> 01:52:29,680 REPRODUCIBLE RESEARCH AND 2965 01:52:29,680 --> 01:52:33,680 PROMOTE PUBLIC TRUST IN 2966 01:52:33,680 --> 01:52:33,960 RESEARCH. 2967 01:52:33,960 --> 01:52:35,880 HERE IS A COMPARISON OF THE 2968 01:52:35,880 --> 01:52:38,280 CURRENT AND NEW POLICY. 2969 01:52:38,280 --> 01:52:41,320 THE CURRENT POLICY APPLIES TO 2970 01:52:41,320 --> 01:52:42,560 ANY APPLICATIONS WITH MORE THAN 2971 01:52:42,560 --> 01:52:44,920 500K DIRECT COSTS PER YEAR. 2972 01:52:44,920 --> 01:52:48,280 AND NEW POLICY WILL APPLY TO ALL 2973 01:52:48,280 --> 01:52:51,680 RESEARCH STUDIES GENERATING THE 2974 01:52:51,680 --> 01:52:53,400 SCIENTIFIC DATA. 2975 01:52:53,400 --> 01:52:55,120 AND IN THE SUBMISSION, CURRENT 2976 01:52:55,120 --> 01:52:56,760 POLICY REQUIRES DATA SHARING 2977 01:52:56,760 --> 01:52:58,720 PLAN TO BE SUBMITTED. 2978 01:52:58,720 --> 01:53:01,080 THE NEW POLICY ADDED AS DATA 2979 01:53:01,080 --> 01:53:03,200 MANAGEMENT PART TO THE PLAN, IF 2980 01:53:03,200 --> 01:53:07,480 YOU LOOK AT THE DEFINITION OF 2981 01:53:07,480 --> 01:53:08,800 DATA MANAGEMENT, IT INCLUDES 2982 01:53:08,800 --> 01:53:14,800 EFFORTS NECESSARY FOR SCIENTIFIC 2983 01:53:14,800 --> 01:53:16,600 RIGOR ANYWAY. 2984 01:53:16,600 --> 01:53:17,520 THE COMPLIANCE EXPECTATION 2985 01:53:17,520 --> 01:53:19,600 REMAINS SIMILAR WITH NOTICEABLE 2986 01:53:19,600 --> 01:53:26,040 CHANGES FOR NEW POLICY SUCH AS 2987 01:53:26,040 --> 01:53:28,720 THE PUBLICATION TRIGGER AND PLAN 2988 01:53:28,720 --> 01:53:30,000 EVALUATION PROCESS. 2989 01:53:30,000 --> 01:53:31,720 JUST TO CLARIFY THE FOCUS IS TO 2990 01:53:31,720 --> 01:53:34,280 HAVE A PLAN TO MANAGE AND SHARE 2991 01:53:34,280 --> 01:53:41,280 THE DATA, IT'S NOT A UNIVERSAL 2992 01:53:41,280 --> 01:53:44,280 REQUIREMENT TO SHARE ALL THE 2993 01:53:44,280 --> 01:53:44,720 DATA. 2994 01:53:44,720 --> 01:53:47,040 A TWO-PART WEBINAR SERIES TO 2995 01:53:47,040 --> 01:53:48,120 OFFER ADDITIONAL CLARIFICATION 2996 01:53:48,120 --> 01:53:53,480 SUCH AS GOALS AND EXCLUSIONS, 2997 01:53:53,480 --> 01:53:54,480 PRELIMINARY ANALYSIS, APPLICABLE 2998 01:53:54,480 --> 01:53:56,200 MECHANISM AND INFORMATION AND 2999 01:53:56,200 --> 01:53:56,960 RESOURCES FOR PLANNED 3000 01:53:56,960 --> 01:54:00,840 DEVELOPMENT AS A MISSION, ET 3001 01:54:00,840 --> 01:54:01,080 CETERA. 3002 01:54:01,080 --> 01:54:04,280 DATA PROVIDED ON THE SLIDE FOR 3003 01:54:04,280 --> 01:54:05,400 SLIDE DECK AND RECORDING FOR 3004 01:54:05,400 --> 01:54:06,800 FIRST SESSION AND REGISTRATION 3005 01:54:06,800 --> 01:54:09,320 INFORMATION FOR THE UPCOMING 3006 01:54:09,320 --> 01:54:09,680 SESSION. 3007 01:54:09,680 --> 01:54:12,720 THE NEW POLICY IS TRANS-NIH 3008 01:54:12,720 --> 01:54:14,080 MINIMUM REQUIREMENT, SPECIAL 3009 01:54:14,080 --> 01:54:15,480 FUNDING OPPORTUNITY ANNOUNCEMENT 3010 01:54:15,480 --> 01:54:17,680 MAY HAVE THEIR OWN REQUIREMENT 3011 01:54:17,680 --> 01:54:19,480 ON THE DATA MANAGEMENT SHARING, 3012 01:54:19,480 --> 01:54:22,760 AND JUST AS MENTIONED IT'S NOT A 3013 01:54:22,760 --> 01:54:23,680 UNIVERSAL REQUIREMENT FOR 3014 01:54:23,680 --> 01:54:26,680 SHARING ALL DATA, ONLY FOCUSING 3015 01:54:26,680 --> 01:54:30,440 ON SCIENTIFIC DATA, WHICH HAS 3016 01:54:30,440 --> 01:54:32,520 THE SUFFICIENT TO VALIDATE AND 3017 01:54:32,520 --> 01:54:33,120 REPLICATE RESEARCH FINDINGS. 3018 01:54:33,120 --> 01:54:39,680 SCOPE OF THE DATA IS APPARENTLY 3019 01:54:39,680 --> 01:54:40,600 PROJECT DEPENDENT. 3020 01:54:40,600 --> 01:54:45,080 A WORKING GROUP WAS FORMED THIS 3021 01:54:45,080 --> 01:54:45,960 YEAR, WORKING GROUP MEMBERS COME 3022 01:54:45,960 --> 01:54:48,880 FROM VARIOUS PARTS OF THE 3023 01:54:48,880 --> 01:54:50,880 INSTITUTES SUCH AS EXTRAMURAL 3024 01:54:50,880 --> 01:54:53,440 SCIENTIFIC PROGRAM DIVISIONS, 3025 01:54:53,440 --> 01:54:54,000 INFORMATION TECHNOLOGISTS, 3026 01:54:54,000 --> 01:54:55,480 REVIEWS, COMMUNICATION. 3027 01:54:55,480 --> 01:54:58,680 THE GOAL IS TO DEVELOP NIBIB'S 3028 01:54:58,680 --> 01:54:59,680 IMPLEMENTATION THAT IS TAILORED 3029 01:54:59,680 --> 01:55:02,760 TO OUR YOUR NUKE NEED AND 3030 01:55:02,760 --> 01:55:04,080 PRIORITIES, WHILE MAINTAINING 3031 01:55:04,080 --> 01:55:08,480 THE COMPATIBILITY WITH THE NIH 3032 01:55:08,480 --> 01:55:08,680 POLICY. 3033 01:55:08,680 --> 01:55:10,720 YOU HAVE PROBABLY SEEN THIS 3034 01:55:10,720 --> 01:55:13,600 SLIDE BEFORE IN PRIOR COUNCIL 3035 01:55:13,600 --> 01:55:14,800 MEETINGS, FROM TECHNOLOGY 3036 01:55:14,800 --> 01:55:16,520 INNOVATION POINT OF VIEW NIBIB 3037 01:55:16,520 --> 01:55:20,480 HAS ITS UNIQUE POSITION IN THE 3038 01:55:20,480 --> 01:55:21,560 NIH FAMILY WHICH PRIORITY 3039 01:55:21,560 --> 01:55:23,520 FOCUSING ON ENGINEERING THE 3040 01:55:23,520 --> 01:55:25,640 FUTURE OF HEALTH. 3041 01:55:25,640 --> 01:55:29,520 NIBIB'S PART OF THE AGE OF 3042 01:55:29,520 --> 01:55:31,080 TECHNOLOGY ENGINEERING ECOSYSTEM 3043 01:55:31,080 --> 01:55:34,360 FOCUS ON DRIVING TECHNOLOGY 3044 01:55:34,360 --> 01:55:36,760 INNOVATIONS WITH BROAD ABILITY 3045 01:55:36,760 --> 01:55:37,680 AND INTERACTING AND 3046 01:55:37,680 --> 01:55:42,560 COLLABORATING WITH OTHER I.C.s 3047 01:55:42,560 --> 01:55:45,280 TOGETHER TO FULFILL THE NIH 3048 01:55:45,280 --> 01:55:47,480 MISSION, MISSION PRIORITY 3049 01:55:47,480 --> 01:55:48,320 DETERMINES UNIQUE RELATIONSHIP 3050 01:55:48,320 --> 01:55:51,080 BETWEEN RESEARCH FINDINGS AND 3051 01:55:51,080 --> 01:55:51,720 DATA. 3052 01:55:51,720 --> 01:55:54,800 LET'S TAKE A CLOSER LOOK. 3053 01:55:54,800 --> 01:56:00,360 THE TYPE OF RESEARCH SUPPORTED 3054 01:56:00,360 --> 01:56:02,520 BY NIH TRADITIONALLY 3055 01:56:02,520 --> 01:56:03,920 HYPOTHESIS-DRIVEN RESEARCH, SUCH 3056 01:56:03,920 --> 01:56:04,880 AS CLINICAL TRIALS. 3057 01:56:04,880 --> 01:56:07,680 THIS TYPE OF RESEARCH USUALLY 3058 01:56:07,680 --> 01:56:08,960 STARTS WITH HYPOTHESIS AND 3059 01:56:08,960 --> 01:56:11,840 INVESTIGATORS NEED TO DESIGN A 3060 01:56:11,840 --> 01:56:12,960 STUDY AND ACQUIRE SIGNIFICANT 3061 01:56:12,960 --> 01:56:17,760 AMOUNT OF DATA WHICH NEEDS TO BE 3062 01:56:17,760 --> 01:56:19,720 MANAGED AS MENTIONED EARLIER, 3063 01:56:19,720 --> 01:56:22,320 AND TO SUPPORT HYPOTHESIS 3064 01:56:22,320 --> 01:56:25,720 TESTING WHICH LEADS TO RESEARCH 3065 01:56:25,720 --> 01:56:26,200 FINDINGS. 3066 01:56:26,200 --> 01:56:29,040 DATA POINTS ARE IMPORTANT ROLE 3067 01:56:29,040 --> 01:56:31,080 HERE TO SUPPORT RESEARCH 3068 01:56:31,080 --> 01:56:35,480 FINDING. 3069 01:56:35,480 --> 01:56:37,520 IN CONTRAST FOR TECHNOLOGY 3070 01:56:37,520 --> 01:56:41,280 DIVERSITIEN RESEARCH SUCH AS 3071 01:56:41,280 --> 01:56:42,840 MATHEMATICAL FRAMEWORK, IMAGING, 3072 01:56:42,840 --> 01:56:46,640 USUALLY START FROM FIRST 3073 01:56:46,640 --> 01:56:47,280 PRINCIPLES WERE ENGINEERING 3074 01:56:47,280 --> 01:56:49,360 DESIGNS WHICH LEAD TO RESEARCH 3075 01:56:49,360 --> 01:56:53,080 AND DEVELOPMENT AND THIS PROCESS 3076 01:56:53,080 --> 01:56:54,200 USUALLY INVOLVES SIGNIFICANT 3077 01:56:54,200 --> 01:56:57,880 AMOUNT OF PRELIMINARY EFFORT AND 3078 01:56:57,880 --> 01:56:59,000 ANALYSIS, BACK AND FORTH, TRIALS 3079 01:56:59,000 --> 01:57:00,640 AND ERRORS, GOING BACK TO THE 3080 01:57:00,640 --> 01:57:04,520 DRAWING BOARD BEFORE ANYTHING 3081 01:57:04,520 --> 01:57:06,200 RISES TO SUFFICIENT QUALITY TO 3082 01:57:06,200 --> 01:57:06,960 BECOME SHARED TECHNOLOGY. 3083 01:57:06,960 --> 01:57:09,600 DEPENDING ON THE NATURE OF THE 3084 01:57:09,600 --> 01:57:13,760 RESEARCH, DATA MAY BE NEEDED IN 3085 01:57:13,760 --> 01:57:16,160 R&D PROCESS, HOWEVER WITH SOME 3086 01:57:16,160 --> 01:57:18,240 EXCEPTIONS THE DATA NEED FOR R&D 3087 01:57:18,240 --> 01:57:21,080 IS USUALLY SMALLER WHEN COMPARED 3088 01:57:21,080 --> 01:57:23,280 WITH THE NEED FROM 3089 01:57:23,280 --> 01:57:25,120 HYPOTHESIS-DRIVEN RESEARCH. 3090 01:57:25,120 --> 01:57:28,280 EVEN FOR DATA-DRIVEN RESEARCH 3091 01:57:28,280 --> 01:57:30,720 THERE ARE USUALLY BENEFITING 3092 01:57:30,720 --> 01:57:34,240 FROM DATA SHARING POLICY, THEY 3093 01:57:34,240 --> 01:57:36,080 ARE CUSTOMERS FOR DATA REUSE. 3094 01:57:36,080 --> 01:57:37,480 TECHNOLOGY FINDINGS MAY IN TURN 3095 01:57:37,480 --> 01:57:40,680 ENABLE THE NEXT GENERATION OF 3096 01:57:40,680 --> 01:57:42,640 TECHNOLOGY INNOVATIONS FOR 3097 01:57:42,640 --> 01:57:45,280 EXAMPLE IN LAST CENTURY THE 3098 01:57:45,280 --> 01:57:49,400 INNOVATION IN MR SCANNERS LEADS 3099 01:57:49,400 --> 01:57:51,160 TO IMAGING SEQUENCES, WHICH 3100 01:57:51,160 --> 01:57:54,880 FURTHER LED TO ADVANCEMENT IN 3101 01:57:54,880 --> 01:57:55,400 NEUROIMAGING SEQUENCE. 3102 01:57:55,400 --> 01:57:58,080 THE TECHNOLOGY MAY ALSO ENABLE 3103 01:57:58,080 --> 01:58:01,520 THE NEXT GENERATION CLINICAL 3104 01:58:01,520 --> 01:58:02,760 RESEARCH BENEFITING 3105 01:58:02,760 --> 01:58:04,120 HYPOTHESIS-DRIVEN RESEARCH BY 3106 01:58:04,120 --> 01:58:04,800 PROVIDING TECHNOLOGYING BRIDGING 3107 01:58:04,800 --> 01:58:07,000 THE GAP IN DATA NEED. 3108 01:58:07,000 --> 01:58:11,920 FOR EXAMPLE ADVANCEMENT IN 3109 01:58:11,920 --> 01:58:13,560 NEUROIMAGING MENTIONED EARLY 3110 01:58:13,560 --> 01:58:14,560 ENABLES ALZHEIMER'S DISEASE 3111 01:58:14,560 --> 01:58:15,520 INITIATIVE STARTING IN 2004 3112 01:58:15,520 --> 01:58:20,640 WHICH IS ALSO SUPPORTED BY THE 3113 01:58:20,640 --> 01:58:21,920 DATA SCIENCE TECHNOLOGY 3114 01:58:21,920 --> 01:58:22,960 DEVELOPED BY CENTERS, DATA 3115 01:58:22,960 --> 01:58:24,480 SHARED BY THIS INITIATIVE IN 3116 01:58:24,480 --> 01:58:27,760 TURN BECOMES RESOURCE FOR NEW 3117 01:58:27,760 --> 01:58:30,480 TECHNOLOGY DEVELOPMENT. 3118 01:58:30,480 --> 01:58:32,920 AS MENTIONED EARLIER, NIBIB IS 3119 01:58:32,920 --> 01:58:34,800 FOCUSED ON TECHNOLOGY 3120 01:58:34,800 --> 01:58:36,640 DEVELOPMENT WITH BROAD 3121 01:58:36,640 --> 01:58:38,280 APPLICABILITY, USUALLY NOT 3122 01:58:38,280 --> 01:58:39,160 DOMAIN SPECIFIC. 3123 01:58:39,160 --> 01:58:42,680 AND WE ALSO HAVE A BROAD 3124 01:58:42,680 --> 01:58:47,560 SPECTRUM IN TERMS OF TYPE OF 3125 01:58:47,560 --> 01:58:49,800 RESEARCH, SUPPORT CLINICAL 3126 01:58:49,800 --> 01:58:51,520 TRIALS, LIMITED TO EARLY STAGE 3127 01:58:51,520 --> 01:58:53,080 AND PHASE 1 STUDIES. 3128 01:58:53,080 --> 01:58:59,440 LET'S COME BACK TO THE GUIDING 3129 01:58:59,440 --> 01:59:00,000 PRINCIPLE, IMPROVED 3130 01:59:00,000 --> 01:59:03,360 REPRODUCIBILITY AND RELIABILITY. 3131 01:59:03,360 --> 01:59:04,640 NIBIB-SUPPORTED RESEARCH 3132 01:59:04,640 --> 01:59:05,680 PUBLICATION IS ONE EFFECTIVE 3133 01:59:05,680 --> 01:59:07,520 AVENUE FOR SHARING RESEARCH 3134 01:59:07,520 --> 01:59:09,600 FINDINGS OR RECIPES FOR 3135 01:59:09,600 --> 01:59:10,120 TECHNOLOGY. 3136 01:59:10,120 --> 01:59:11,800 FOR EXAMPLE, THE MATHEMATICAL 3137 01:59:11,800 --> 01:59:15,400 FRAMEWORK IN THIS PAPER FOR THE 3138 01:59:15,400 --> 01:59:17,880 BOUNDARY CONDITIONS IN OPTICAL 3139 01:59:17,880 --> 01:59:19,960 IMAGING, THEY ACTUALLY ENABLED 3140 01:59:19,960 --> 01:59:20,720 NUMEROUS FURTHER TECHNOLOGY 3141 01:59:20,720 --> 01:59:24,560 INNOVATIONS IN THE OPTICAL 3142 01:59:24,560 --> 01:59:27,000 IMAGING FIELD. 3143 01:59:27,000 --> 01:59:31,200 AND IN TECHNOLOGY FOCUSED FIELD 3144 01:59:31,200 --> 01:59:33,200 PUBLICATION INCLUDES MANY FORMS. 3145 01:59:33,200 --> 01:59:37,560 SUCH AS PEER REVIEWED JOURNALS, 3146 01:59:37,560 --> 01:59:39,440 CONFERENCE PAPER, PRE-PRINT, 3147 01:59:39,440 --> 01:59:40,760 ENABLE TECHNOLOGY CHANGE, 3148 01:59:40,760 --> 01:59:42,080 ESPECIALLY IN PANDEMIC RESPONSE, 3149 01:59:42,080 --> 01:59:45,320 AND THEY ALSO PROVIDE AVENUE TO 3150 01:59:45,320 --> 01:59:46,600 SHARE TECHNOLOGY FINDINGS OR 3151 01:59:46,600 --> 01:59:47,800 LESSONS LEARNED. 3152 01:59:47,800 --> 01:59:49,200 THE DATA AND INFORMATION 3153 01:59:49,200 --> 01:59:51,400 PROVIDED IN THE PUBLICATION 3154 01:59:51,400 --> 01:59:56,600 USUALLY PLAYS AN IMPORTANT ROLE 3155 01:59:56,600 --> 02:00:00,320 FOR RELIABLE REPRODUCTION, IT'S 3156 02:00:00,320 --> 02:00:01,720 ASSOCIATE MATHEMATICAL 3157 02:00:01,720 --> 02:00:03,600 FRAMEWORK, ESSENTIAL TO 3158 02:00:03,600 --> 02:00:13,520 REPRODUCE M.R. IMAGING SEQUENCE. 3159 02:00:13,520 --> 02:00:15,160 SCIENTIFIC INFORMATION DOES NOT 3160 02:00:15,160 --> 02:00:18,600 REMAIN SPECIFIC, REPOSITORIES 3161 02:00:18,600 --> 02:00:20,440 SUCH AS ECOSYSTEM THAT NIH IS 3162 02:00:20,440 --> 02:00:22,720 BUILDING RIGHT NOW MAY OFFER 3163 02:00:22,720 --> 02:00:24,040 SUFFICIENT AND LOW COST 3164 02:00:24,040 --> 02:00:28,360 SOLUTIONS FOR DATA SHARING 3165 02:00:28,360 --> 02:00:28,560 NEEDS. 3166 02:00:28,560 --> 02:00:32,360 AND AS MENTIONED EARLIER, IN 3167 02:00:32,360 --> 02:00:33,920 ADDITION TO BROAD ACCESSIBILITY, 3168 02:00:33,920 --> 02:00:36,440 SUPPORTS VARIOUS TYPES OF 3169 02:00:36,440 --> 02:00:40,280 RESEARCH IF A RESEARCH IS 3170 02:00:40,280 --> 02:00:43,280 FOCUSING ON DEVELOPING RECIPES 3171 02:00:43,280 --> 02:00:44,880 FOR TECHNOLOGY AND ENGINEERING 3172 02:00:44,880 --> 02:00:49,240 DESIGNS SUCH AS OPTICAL IMAGING 3173 02:00:49,240 --> 02:00:53,160 EXAMPLE SHOWN EARLIER. 3174 02:00:53,160 --> 02:00:54,880 TECHNOLOGY OUTCOME SHARED 3175 02:00:54,880 --> 02:00:56,920 THROUGH PUBLICATION WAS MINIMAL 3176 02:00:56,920 --> 02:00:58,160 SCIENTIFIC DATA NEED BEYOND THE 3177 02:00:58,160 --> 02:00:59,800 PUBLICATION AND SUPPORTING DATA 3178 02:00:59,800 --> 02:01:02,400 CAN BE SHARED AS SUPPLEMENTAL 3179 02:01:02,400 --> 02:01:07,320 INFORMATION OR USING GENERAL 3180 02:01:07,320 --> 02:01:08,160 REPOSITORY. 3181 02:01:08,160 --> 02:01:10,160 SOME ENGINEERING DESIGN PROJECT 3182 02:01:10,160 --> 02:01:11,680 MAY GENERATE ADDITIONAL 3183 02:01:11,680 --> 02:01:14,000 SUPPORTING DATA, HERE IS THE 3184 02:01:14,000 --> 02:01:17,240 EXAMPLE TO DEVELOP NOVEL 3185 02:01:17,240 --> 02:01:18,440 NANOPARTICLES TO BRING DELIVERY 3186 02:01:18,440 --> 02:01:21,200 AND RECIPE OF TECHNOLOGY IS 3187 02:01:21,200 --> 02:01:21,720 SHARED WHILE PUBLICATION, 3188 02:01:21,720 --> 02:01:24,280 WHEREAS THE ACTUAL MATERIAL IS 3189 02:01:24,280 --> 02:01:26,240 SHARED WHILE MATERIAL TRANSFER 3190 02:01:26,240 --> 02:01:27,880 AGREEMENTS, THERE MAY BE 3191 02:01:27,880 --> 02:01:29,440 ADDITIONAL SUPPORTING DATA LIKE 3192 02:01:29,440 --> 02:01:32,560 ANIMAL STUDY OR OTHER METADATA, 3193 02:01:32,560 --> 02:01:35,040 TO SUPPORT THE RESEARCH OUTCOMES 3194 02:01:35,040 --> 02:01:40,080 WHICH CAN BE FURTHER SHARED AS 3195 02:01:40,080 --> 02:01:43,840 SUPPLEMENTARY INFORMATION OR 3196 02:01:43,840 --> 02:01:44,680 GENERATE THROUGH GENERALIST 3197 02:01:44,680 --> 02:01:47,480 REPOSITORY, THERE MAY BE IN SOME 3198 02:01:47,480 --> 02:01:54,120 CASE SPECIFIC REPOSITORY, IN 3199 02:01:54,120 --> 02:01:55,480 THIS CASE NANOMEDICINE 3200 02:01:55,480 --> 02:01:55,880 REPOSITORY. 3201 02:01:55,880 --> 02:02:10,280 IN SOME CASES WE SUPPORT 3202 02:02:10,280 --> 02:02:11,480 DATA-DRIVEN OR HYPOTHESIS-DRIVEN 3203 02:02:11,480 --> 02:02:16,680 APPROACHES, THERE'S A MODEL WITH 3204 02:02:16,680 --> 02:02:17,280 PROSPECTIVE CLINICAL STUDY, 3205 02:02:17,280 --> 02:02:20,680 METHODS AND KEY FINDINGS SHARED 3206 02:02:20,680 --> 02:02:22,400 WITH PUBLICATIONS, SOFTWARE 3207 02:02:22,400 --> 02:02:26,440 SHARED WITH OTHER CHANNELS, 3208 02:02:26,440 --> 02:02:29,600 THERE MIGHT BE DATA GENERATED TO 3209 02:02:29,600 --> 02:02:32,520 SUPPORT RESEARCH OUTCOME. 3210 02:02:32,520 --> 02:02:34,200 NIH SHARES WEBSITE PROVIDES 3211 02:02:34,200 --> 02:02:35,080 ADDITIONAL GUIDELINE FOR 3212 02:02:35,080 --> 02:02:35,880 PROVIDING DATA MANAGEMENT 3213 02:02:35,880 --> 02:02:37,880 SHARING PLAN AS WELL AS SOME 3214 02:02:37,880 --> 02:02:40,880 GUIDANCE HOW TO SELECT THE 3215 02:02:40,880 --> 02:02:41,960 PROPER REPOSITORIES. 3216 02:02:41,960 --> 02:02:45,680 PLEASE NOTE THE LAST TYPE OF 3217 02:02:45,680 --> 02:02:49,840 PROJECT IS THE CURRENT 3218 02:02:49,840 --> 02:02:51,400 PORTFOLIO, DUE TO LIMITATIONS ON 3219 02:02:51,400 --> 02:02:52,360 CLINICAL TRIALS, SIGNIFICANT 3220 02:02:52,360 --> 02:02:54,680 PORTION OF DATA DRIVEN 3221 02:02:54,680 --> 02:02:57,720 APPROACHES, SECONDARY DATA 3222 02:02:57,720 --> 02:03:01,480 ANALYSIS AS MENTIONED BEFORE. 3223 02:03:01,480 --> 02:03:06,080 SO, RIGHT NOW NIH CONTINUES TO 3224 02:03:06,080 --> 02:03:09,040 BACK INVESTIGATORS TO PUBLISH 3225 02:03:09,040 --> 02:03:10,560 RESEARCH FINDINGS, INCLUDING 3226 02:03:10,560 --> 02:03:12,960 POSITIVE OUTCOMES AS WELL AS 3227 02:03:12,960 --> 02:03:15,360 LESSONS LEARNED AND CAN CONSIDER 3228 02:03:15,360 --> 02:03:19,840 RAISING ALL THE FORMS OF 3229 02:03:19,840 --> 02:03:20,680 PUBLICATION, INCLUDING JOURNAL, 3230 02:03:20,680 --> 02:03:25,760 CONFERENCE PAPER, PRE-PRINTS 3231 02:03:25,760 --> 02:03:30,040 WITH DOIs, AND THE SCIENTIFIC 3232 02:03:30,040 --> 02:03:31,480 DATA FOR REPRODUCING PUBLISHED 3233 02:03:31,480 --> 02:03:34,600 TECHNOLOGY, AND SHARE DATA IN 3234 02:03:34,600 --> 02:03:34,880 PUBLICATION. 3235 02:03:34,880 --> 02:03:39,000 AND AS USUAL THE PROGRAM STAFF 3236 02:03:39,000 --> 02:03:41,400 IS HERE TO HELP. 3237 02:03:41,400 --> 02:03:43,160 ADDITIONAL GUIDANCE HERE, IF YOU 3238 02:03:43,160 --> 02:03:44,360 ARE INVESTIGATOR, THEN YOU 3239 02:03:44,360 --> 02:03:46,200 SHOULD CONSIDER DEVELOPING A 3240 02:03:46,200 --> 02:03:49,160 PLAN RELEVANT TO YOUR PROJECT 3241 02:03:49,160 --> 02:03:51,360 LEVERAGING RESOURCES PROVIDED BY 3242 02:03:51,360 --> 02:03:53,880 NIH DATA MANAGED SHARING WEBSITE 3243 02:03:53,880 --> 02:03:56,120 AS WELL AS OTHER PUBLIC TOOLS 3244 02:03:56,120 --> 02:03:58,520 THAT IS AVAILABLE TO YOU. 3245 02:03:58,520 --> 02:04:02,080 AND JUST TO CLARIFY THAT THE 3246 02:04:02,080 --> 02:04:03,480 POLICY IS THE MAIN REQUIREMENT, 3247 02:04:03,480 --> 02:04:05,880 P.I. MAY CHOOSE TO GO ABOVE AND 3248 02:04:05,880 --> 02:04:07,920 BEYOND AND TO USE WHATEVER THEY 3249 02:04:07,920 --> 02:04:13,880 THINK IS THE BEST PROCESS FOR 3250 02:04:13,880 --> 02:04:15,120 ENABLE DATA SHARING REUSE. 3251 02:04:15,120 --> 02:04:17,320 USUALLY FOR OUR PROJECT 3252 02:04:17,320 --> 02:04:21,160 SHAREABLE DATA PROBABLY WOULD BE 3253 02:04:21,160 --> 02:04:23,480 THE DATA THAT ACCOMPANIES 3254 02:04:23,480 --> 02:04:24,080 PUBLICATION, FOR ANY QUESTIONS, 3255 02:04:24,080 --> 02:04:27,160 FOR EXAMPLE, YOU COULD HAVE 3256 02:04:27,160 --> 02:04:28,160 SCIENTIFIC DATA WITHOUT 3257 02:04:28,160 --> 02:04:29,480 PUBLICATION, PLEASE FOLLOW THE 3258 02:04:29,480 --> 02:04:32,560 NIH GUIDANCE AS WELL AS 3259 02:04:32,560 --> 02:04:36,120 CONTACTING OUR PROGRAM STAFF. 3260 02:04:36,120 --> 02:04:39,440 AND NIH SHARE WEBSITE IS 3261 02:04:39,440 --> 02:04:41,480 OFFERING A ONE-STOP SHOP FOR 3262 02:04:41,480 --> 02:04:42,160 DEVELOPING DATA MANAGEMENT 3263 02:04:42,160 --> 02:04:44,760 SHARING PLAN AS WELL AS OTHER 3264 02:04:44,760 --> 02:04:47,920 PART OF RESOURCE SHARING PLAN 3265 02:04:47,920 --> 02:04:51,520 AND IT'S ANTICIPATED THAT THE 3266 02:04:51,520 --> 02:04:53,400 MORE RESOURCES LIKE TEMPLATES 3267 02:04:53,400 --> 02:04:55,640 AND PLANS MAY BE AVAILABLE IN 3268 02:04:55,640 --> 02:04:57,280 THE FUTURE. 3269 02:04:57,280 --> 02:05:02,720 SO WITH THAT I'M OPEN FOR 3270 02:05:02,720 --> 02:05:03,240 DISCUSSION. 3271 02:05:03,240 --> 02:05:04,160 THANK YOU. 3272 02:05:04,160 --> 02:05:05,280 >> GREAT. 3273 02:05:05,280 --> 02:05:11,600 THANK YOU VERY MUCH, QI. 3274 02:05:11,600 --> 02:05:13,080 COUNCIL MEMBERS, ANY QUESTIONS 3275 02:05:13,080 --> 02:05:22,000 OR COMMENTS FOR QI? 3276 02:05:22,000 --> 02:05:22,520 >> I'LL GO FIRST. 3277 02:05:22,520 --> 02:05:24,280 I THINK THIS IS AN EXCELLENT 3278 02:05:24,280 --> 02:05:24,680 IDEA. 3279 02:05:24,680 --> 02:05:26,240 I OFTEN MAKE A STATEMENT TO 3280 02:05:26,240 --> 02:05:28,720 PEOPLE THAT I FOUND PUBLICATIONS 3281 02:05:28,720 --> 02:05:30,240 ARE NO LONGER REPRODUCIBLE AND 3282 02:05:30,240 --> 02:05:30,920 PRETTY WORTHLESS WITHOUT A LOT 3283 02:05:30,920 --> 02:05:40,360 OF DATA YOU NEED FROM THE LABS. 3284 02:05:40,360 --> 02:05:42,200 THEY ARE NEW NICHE. 3285 02:05:42,200 --> 02:05:48,080 AT THE FDA WE STARTED PUTTING 3286 02:05:48,080 --> 02:05:49,200 TOGETHER CATALOG. 3287 02:05:49,200 --> 02:05:51,040 ANYTHING WE GENERATE, ANY 3288 02:05:51,040 --> 02:05:53,240 PROGRAMS WE'RE USING AS FAR AS 3289 02:05:53,240 --> 02:05:53,880 INTERNALLY GENERATED PROGRAMS 3290 02:05:53,880 --> 02:05:58,560 BEING UTILIZED TO ANALYZE DATA, 3291 02:05:58,560 --> 02:06:00,040 PUBLISH CASES, TO HELP REPRODUCE 3292 02:06:00,040 --> 02:06:01,960 THE DATA, IT'S A GREAT IDEA TO 3293 02:06:01,960 --> 02:06:03,360 GET THINGS MOVING IN THAT 3294 02:06:03,360 --> 02:06:07,800 DIRECTION WHERE THINGS ARE MORE 3295 02:06:07,800 --> 02:06:08,720 REPRODUCIBLE. 3296 02:06:08,720 --> 02:06:10,800 >> THANK YOU. 3297 02:06:10,800 --> 02:06:13,080 >> GREAT. 3298 02:06:13,080 --> 02:06:13,280 THANKS. 3299 02:06:13,280 --> 02:06:14,720 FANTASTIC, I KNOW FDA IS 3300 02:06:14,720 --> 02:06:15,840 STRONGLY CONSIDERING A PARALLEL 3301 02:06:15,840 --> 02:06:26,240 EFFORT OF THEIR OWN ACCORD. 3302 02:06:26,240 --> 02:06:26,400 SAM? 3303 02:06:26,400 --> 02:06:28,480 >> THANK YOU AGAIN. 3304 02:06:28,480 --> 02:06:30,520 THAT WAS GREAT PRESENTATION. 3305 02:06:30,520 --> 02:06:34,760 ONE OF THE CHALLENGES WE FACE IN 3306 02:06:34,760 --> 02:06:40,480 ACADEMIA IS THIS, IS THAT USING 3307 02:06:40,480 --> 02:06:46,480 LAB NOTEBOOKS TO RECORD DATA, 3308 02:06:46,480 --> 02:06:47,880 GRADUATE STUDENTS ARE FINISHED 3309 02:06:47,880 --> 02:06:50,080 AND GONE, YOU WANT TO REASSESS 3310 02:06:50,080 --> 02:06:52,400 DATA, YOU CAN'T FIND YOUR LAB 3311 02:06:52,400 --> 02:06:53,280 NOTEBOOK. 3312 02:06:53,280 --> 02:06:57,280 IS THERE A MOVE THAT COULD BE 3313 02:06:57,280 --> 02:07:00,360 SUPPORTED GENERALLY LAB NOTEBOOK 3314 02:07:00,360 --> 02:07:01,680 FOR NIH-SPONSORED INVESTIGATORS 3315 02:07:01,680 --> 02:07:04,520 SUCH THAT AT LEAST THEY CAN BE 3316 02:07:04,520 --> 02:07:07,000 RETRIEVED AT ANY POINT IN TIME. 3317 02:07:07,000 --> 02:07:12,640 I DON'T KNOW ABOUT YOU GUYS, BUT 3318 02:07:12,640 --> 02:07:17,480 IT'S BEEN SOME TIME AND GRADUATE 3319 02:07:17,480 --> 02:07:19,520 STUDENT IS GONE, SO IS THERE A 3320 02:07:19,520 --> 02:07:24,560 MOVE TO MOVE TO ELECTRONIC LAB 3321 02:07:24,560 --> 02:07:26,080 NOTEBOOK THAT WE CAN SEE THE 3322 02:07:26,080 --> 02:07:28,480 RESPONSE FOR A LONG TIME? 3323 02:07:28,480 --> 02:07:32,080 >> YEAH, THANK YOU FOR THAT 3324 02:07:32,080 --> 02:07:33,080 COMMENT. 3325 02:07:33,080 --> 02:07:34,640 THAT'S ACTUALLY THE REASON WHY 3326 02:07:34,640 --> 02:07:38,440 NIH ARE ADDING DATA MANAGEMENT 3327 02:07:38,440 --> 02:07:41,640 INTO THE PLAN THAT IS REQUIRING 3328 02:07:41,640 --> 02:07:43,360 THE INVESTIGATORS TO CONSIDER 3329 02:07:43,360 --> 02:07:50,480 DATA MANAGEMENT BEFORE A PROJECT 3330 02:07:50,480 --> 02:07:51,080 IS STARTED. 3331 02:07:51,080 --> 02:07:54,200 IF YOU LOOK AT DEFINITION, 3332 02:07:54,200 --> 02:07:55,880 ENSURING KEY INFORMATION THAT 3333 02:07:55,880 --> 02:08:00,480 HAS BEEN KEPT IN A WAY THAT CAN 3334 02:08:00,480 --> 02:08:02,720 BE REPRODUCIBLY REUSED, EVEN FOR 3335 02:08:02,720 --> 02:08:07,280 THEIR OWN TEAM MEMBERS AND 3336 02:08:07,280 --> 02:08:09,240 THAT'S EXACTLY EFFORT AND 3337 02:08:09,240 --> 02:08:13,880 INVESTIGATOR SHOULD DO TO ENSURE 3338 02:08:13,880 --> 02:08:18,000 THE PROPER SCIENTIFIC RIGOR. 3339 02:08:18,000 --> 02:08:20,160 ONE OF THE ASPECTS OF THE NEW 3340 02:08:20,160 --> 02:08:22,240 DATA SHARING POLICY IS CODIFY 3341 02:08:22,240 --> 02:08:24,520 DATA MANAGEMENT AS PART OF 3342 02:08:24,520 --> 02:08:26,240 EXPECTATION FOR ALL 3343 02:08:26,240 --> 02:08:26,960 NIH-SUPPORTED RESEARCH THAT 3344 02:08:26,960 --> 02:08:28,480 REQUIRES INVESTIGATOR TO PUT IN 3345 02:08:28,480 --> 02:08:32,720 EFFORT TO HAVE A FRAMEWORK THAT 3346 02:08:32,720 --> 02:08:34,280 IS APPLICABLE TO THEIR OWN 3347 02:08:34,280 --> 02:08:37,560 PROJECT, TO ENSURE PROPER DATA 3348 02:08:37,560 --> 02:08:38,520 MANAGEMENT. 3349 02:08:38,520 --> 02:08:46,680 ON THE SECOND ASPECT OF NIH 3350 02:08:46,680 --> 02:08:51,880 PUSHING FOR ELECTRONIC NOTEBOOK, 3351 02:08:51,880 --> 02:08:56,480 THEY DO HAVE BROAD SPECTRUM OF 3352 02:08:56,480 --> 02:09:02,080 PROJECTS, AND LIKE MOST OF THE 3353 02:09:02,080 --> 02:09:03,040 POLICY NIH ACTUALLY GAVE 3354 02:09:03,040 --> 02:09:04,360 FLEXIBILITY TO P.I. TO CONSIDER 3355 02:09:04,360 --> 02:09:07,520 AND DEVELOP A PLAN SUITABLE FOR 3356 02:09:07,520 --> 02:09:09,160 THEIR OWN CASE. 3357 02:09:09,160 --> 02:09:14,440 AND AT THE MOMENT THERE'S NO 3358 02:09:14,440 --> 02:09:16,480 UNIVERSAL REQUIREMENT TO HAVE, 3359 02:09:16,480 --> 02:09:18,560 YOU KNOW, DICTATING ALL HAS TO 3360 02:09:18,560 --> 02:09:20,520 BE ELECTRONIC AND LAB NOTEBOOK 3361 02:09:20,520 --> 02:09:21,520 IS NOT CONSIDERED SCIENTIFIC 3362 02:09:21,520 --> 02:09:24,920 DATA TO BE SHARED BY THE CURRENT 3363 02:09:24,920 --> 02:09:27,720 POLICY AND SO IT IS A GOOD 3364 02:09:27,720 --> 02:09:30,960 PRACTICE FOR P.I. THAT, YOU 3365 02:09:30,960 --> 02:09:32,120 KNOW, I PROBABLY PERSONALLY WILL 3366 02:09:32,120 --> 02:09:36,200 RECOMMEND BUT IT DEPEND ON 3367 02:09:36,200 --> 02:09:41,760 INVESTIGATOR TO DEVISE A MAN FOR 3368 02:09:41,760 --> 02:09:42,280 THE SITUATION. 3369 02:09:42,280 --> 02:09:43,880 >> THANK YOU. 3370 02:09:43,880 --> 02:09:44,880 >> THANK YOU. 3371 02:09:44,880 --> 02:09:48,320 I SEE GOING BETWEEN PICTURES, 3372 02:09:48,320 --> 02:09:50,360 SIMON AND CYNTHIA AND MARYELLEN. 3373 02:09:50,360 --> 02:09:52,880 IF I WENT OUT OF ORDER, SORRY 3374 02:09:52,880 --> 02:09:53,560 ABOUT THAT. 3375 02:09:53,560 --> 02:09:55,680 >> HI, YEAH, THAT WAS A REALLY 3376 02:09:55,680 --> 02:09:56,880 GREAT PRESENTATION. 3377 02:09:56,880 --> 02:10:00,080 I HAD A QUESTION ABOUT SHARING 3378 02:10:00,080 --> 02:10:02,120 HUMAN IMAGING DATA, SOMETHING 3379 02:10:02,120 --> 02:10:05,880 WE'VE BEEN DOING A LOT THE LAST 3380 02:10:05,880 --> 02:10:07,640 COUPLE YEARS, AND WE'RE RUNNING 3381 02:10:07,640 --> 02:10:12,800 INTO QUITE A LOT OF 3382 02:10:12,800 --> 02:10:13,280 INCONSISTENCIES ABOUT 3383 02:10:13,280 --> 02:10:15,920 ANONYMIZATION IN TERMS OF FACIAL 3384 02:10:15,920 --> 02:10:17,960 RECOGNITION, WITH OUR ADVANCED 3385 02:10:17,960 --> 02:10:20,440 IMAGING TECHNOLOGIES TODAY YOU 3386 02:10:20,440 --> 02:10:22,360 CAN RENDER FACES. 3387 02:10:22,360 --> 02:10:23,360 THERE ARE TOOLS OUT THERE, M.R. 3388 02:10:23,360 --> 02:10:25,480 COMMUNITY HAS BEEN USING THEM 3389 02:10:25,480 --> 02:10:26,320 FOR QUITE A WHILE. 3390 02:10:26,320 --> 02:10:30,360 WE'RE SEEING A LOT OF DEBATE 3391 02:10:30,360 --> 02:10:31,880 BETWEEN IRB DATA SHARING AN 3392 02:10:31,880 --> 02:10:33,440 PEOPLE AND I'M WONDERING WHAT 3393 02:10:33,440 --> 02:10:36,080 NIH'S GUIDANCE IS ON THIS AND 3394 02:10:36,080 --> 02:10:37,160 WHETHER THERE MIGHT BE TOOLS 3395 02:10:37,160 --> 02:10:41,800 DEVELOPED THAT WE COULD SHARE AS 3396 02:10:41,800 --> 02:10:46,760 A COMMUNITY THAT WOULD HELP US 3397 02:10:46,760 --> 02:10:53,440 SHARE DATA IN AN ANONYMIZED. 3398 02:10:53,440 --> 02:11:02,200 >> THANK YOU, GREAT QUESTION AND 3399 02:11:02,200 --> 02:11:02,880 SUGGESTION. 3400 02:11:02,880 --> 02:11:04,720 DATA SHARING IS NOT STARTING 3401 02:11:04,720 --> 02:11:04,920 TODAY. 3402 02:11:04,920 --> 02:11:06,880 IT'S ALREADY STARTED. 3403 02:11:06,880 --> 02:11:11,520 THE POLICY STARTED IN 2003, AND 3404 02:11:11,520 --> 02:11:13,480 WITH WITH ADVANCE OF DATA SIGHEN 3405 02:11:13,480 --> 02:11:15,040 AND DATA SHARING IN PARALLEL 3406 02:11:15,040 --> 02:11:20,080 THERE ARE LESSONS LEARNED ALONG 3407 02:11:20,080 --> 02:11:31,320 THE PROCESS LIKE OFFICIAL 3408 02:11:31,320 --> 02:11:31,680 RECOMMENDATION 3409 02:11:31,680 --> 02:11:33,400 MAY NOT BE A CONCERN TEN YEARS 3410 02:11:33,400 --> 02:11:40,320 AGO BUT INCREASING A CONCERN IN 3411 02:11:40,320 --> 02:11:40,760 RECENT DEVELOPMENT. 3412 02:11:40,760 --> 02:11:43,080 THERE ARE EFFORTS TO DEVELOP 3413 02:11:43,080 --> 02:11:44,800 PROPER TOOLS FOR ANONYMIZATION, 3414 02:11:44,800 --> 02:11:47,880 BUT FROM DATA MANAGEMENT SHARING 3415 02:11:47,880 --> 02:11:50,240 POLICY POINT OF VIEW, THERE ARE 3416 02:11:50,240 --> 02:11:52,600 ADDITIONAL GUIDANCE PROVIDED ON 3417 02:11:52,600 --> 02:11:55,800 THE NIH DATA MANAGEMENT SHARING 3418 02:11:55,800 --> 02:11:58,680 WEBSITE, FOR CONSIDERATIONS WHEN 3419 02:11:58,680 --> 02:12:00,520 YOU'RE HANDLING SENSITIVE DATA 3420 02:12:00,520 --> 02:12:03,920 INCLUDING PATIENT DATA THAT 3421 02:12:03,920 --> 02:12:05,120 THERE ARE MULTI-FACETED ASPECTS 3422 02:12:05,120 --> 02:12:06,960 THAT YOU NEED TO CONSIDER FROM 3423 02:12:06,960 --> 02:12:11,480 THE INFORMED CONSENT AND HOW YOU 3424 02:12:11,480 --> 02:12:13,200 CHOOSE THE REPOSITORY AND THERE 3425 02:12:13,200 --> 02:12:19,040 ARE SITUATIONS THAT MAY MAYBE 3426 02:12:19,040 --> 02:12:20,520 SHARING DATA IS PROHIBITED BY 3427 02:12:20,520 --> 02:12:23,600 REGULATIONS AND SPECIFIC 3428 02:12:23,600 --> 02:12:24,680 RESEARCH AGREEMENTS, SO THE 3429 02:12:24,680 --> 02:12:26,080 INVESTIGATOR IN GENERAL YOU 3430 02:12:26,080 --> 02:12:28,480 SHOULD LOOK AT THE SITUATION 3431 02:12:28,480 --> 02:12:30,680 THAT YOU ARE DEALING WITH AND 3432 02:12:30,680 --> 02:12:31,920 WHAT'S THE PROJECT AND WHAT'S 3433 02:12:31,920 --> 02:12:42,840 THE DATA INVOLVED AND WHAT'S THE 3434 02:12:42,840 --> 02:12:45,920 SCIENTIFIC DATA PART TO SHARE 3435 02:12:45,920 --> 02:12:47,800 AND LOOK AT THE PROPER WAY TO 3436 02:12:47,800 --> 02:12:48,000 SHARE. 3437 02:12:48,000 --> 02:12:50,080 THE REQUIREMENT IS NOT TO SHARE 3438 02:12:50,080 --> 02:13:00,680 DATA, IT'S TO MAXIMIZE DATA 3439 02:13:00,680 --> 02:13:00,920 SHARING. 3440 02:13:00,920 --> 02:13:03,280 IF THERE'S NO GOOD WAY TO 3441 02:13:03,280 --> 02:13:04,480 DE-IDENTIFY DATA, WHAT'S THE 3442 02:13:04,480 --> 02:13:07,320 RISK FOR THE INDIVIDUAL SUBJECT 3443 02:13:07,320 --> 02:13:12,360 AND THERE COULD BE FACTORS TO BE 3444 02:13:12,360 --> 02:13:14,120 CONSIDERED, DATA SHARING, ALSO 3445 02:13:14,120 --> 02:13:16,880 ACCEPTABLE BY CURRENT POLICY. 3446 02:13:16,880 --> 02:13:19,240 SO, IT'S CASE BY CASE, IT'S NOT 3447 02:13:19,240 --> 02:13:21,560 A STRAIGHT ANSWER TO THE 3448 02:13:21,560 --> 02:13:25,080 QUESTION, RESEARCH STILL ONGOING 3449 02:13:25,080 --> 02:13:26,840 BUT FOR INDIVIDUAL PROJECT 3450 02:13:26,840 --> 02:13:29,000 RECOMMEND TO CONTACT THE PROGRAM 3451 02:13:29,000 --> 02:13:32,200 STAFF TO DISCUSS AND IN DETAIL 3452 02:13:32,200 --> 02:13:37,600 AND I HOPE THAT ANSWERS YOUR 3453 02:13:37,600 --> 02:13:41,040 QUESTION TO SOME EXTENT. 3454 02:13:41,040 --> 02:13:41,400 >> THANK YOU. 3455 02:13:41,400 --> 02:13:42,880 >> VERY IMPORTANT THING WE NEED 3456 02:13:42,880 --> 02:13:44,640 TO FACTOR IN AT NIH. 3457 02:13:44,640 --> 02:13:49,000 SO THANK YOU. 3458 02:13:49,000 --> 02:13:49,880 CYNTHIA AND THEN MARYELLEN. 3459 02:13:49,880 --> 02:13:52,280 >> THANK YOU FOR EVERYTHING 3460 02:13:52,280 --> 02:13:53,960 THAT'S BEEN SHARED TODAY, BRUCE 3461 02:13:53,960 --> 02:13:55,440 AND JILL. 3462 02:13:55,440 --> 02:14:01,560 I'M EXTREMELY PROUD TO BE 3463 02:14:01,560 --> 02:14:02,960 PARTICIPATING IN NIBIB COUNCIL, 3464 02:14:02,960 --> 02:14:04,280 HEARING ALL TREMENDOUS THINGS 3465 02:14:04,280 --> 02:14:05,480 BEING DONE. 3466 02:14:05,480 --> 02:14:07,240 THE PRESENTATION WAS PRIMARILY 3467 02:14:07,240 --> 02:14:10,320 ABOUT POLICIES BUT I'M WONDERING 3468 02:14:10,320 --> 02:14:12,840 ABOUT RESOURCES AND WHETHER FOR 3469 02:14:12,840 --> 02:14:15,240 IMAGING DATA THIS IS SOMETHING 3470 02:14:15,240 --> 02:14:17,000 EVEN THAT MIDRC MIGHT HAVE A 3471 02:14:17,000 --> 02:14:19,080 ROLE IN FOR ONE OF MY GRANTS WE 3472 02:14:19,080 --> 02:14:22,720 MADE A VERY LARGE DATASET OF 3473 02:14:22,720 --> 02:14:26,960 IMAGE DATA AND PROJECTION DATA 3474 02:14:26,960 --> 02:14:29,200 THAT THE NATIONAL CANCER 3475 02:14:29,200 --> 02:14:30,640 INSTITUTE'S IMAGE ARCHIVE 3476 02:14:30,640 --> 02:14:31,480 PROGRAM HAS MADE AVAILABLE SPACE 3477 02:14:31,480 --> 02:14:36,080 FOR US TO SHARE IT. 3478 02:14:36,080 --> 02:14:37,720 IT'S A SLOW PROCESS FOR THEIR 3479 02:14:37,720 --> 02:14:38,960 CURATION AND THEY HAVE PEOPLE 3480 02:14:38,960 --> 02:14:40,600 THAT NEED FUNDING. 3481 02:14:40,600 --> 02:14:44,440 I'M JUST WONDERING WHETHER 3482 02:14:44,440 --> 02:14:46,280 NIBIB, NOW THAT WE'RE COMING UP 3483 02:14:46,280 --> 02:14:49,560 WITH THESE STANDARDS FOR DATA 3484 02:14:49,560 --> 02:14:52,880 SHARING, CAN FACILITATE A WAY TO 3485 02:14:52,880 --> 02:14:55,480 GET DATASETS OUT THERE, I SEE 3486 02:14:55,480 --> 02:14:58,560 MARYELLEN SHAKING HER HEAD. 3487 02:14:58,560 --> 02:14:59,800 THAT WAS MY COMMENT. 3488 02:14:59,800 --> 02:15:07,120 >> YEAH, THANK YOU FOR THE 3489 02:15:07,120 --> 02:15:07,920 COMMENT. 3490 02:15:07,920 --> 02:15:12,040 I WILL START WITH THE ONE-STOP 3491 02:15:12,040 --> 02:15:13,440 SHOP AT NIH SHARING WEBSITE, 3492 02:15:13,440 --> 02:15:16,880 THAT I HAD IN THE LAST SLIDE. 3493 02:15:16,880 --> 02:15:21,080 AND IN THERE THEY HAVE SEVERAL 3494 02:15:21,080 --> 02:15:23,320 RESOURCES, GUIDANCE TO HELP 3495 02:15:23,320 --> 02:15:28,280 DEVELOPING THE DATA MANAGEMENT 3496 02:15:28,280 --> 02:15:29,120 SHARING PLAN, INCLUDING THE 3497 02:15:29,120 --> 02:15:29,760 RESOURCES. 3498 02:15:29,760 --> 02:15:32,200 FOR EXAMPLE, THEY HAVE SOME 3499 02:15:32,200 --> 02:15:37,280 GUIDANCE AND THE TOOLS TO HELP 3500 02:15:37,280 --> 02:15:39,880 TO ESTIMATE RESOURCES NEEDED IF 3501 02:15:39,880 --> 02:15:42,000 YOU ARE DEVELOPING OR WANT TO 3502 02:15:42,000 --> 02:15:44,920 SHARE IMAGING DATA. 3503 02:15:44,920 --> 02:15:49,200 ALSO, IN THE SECTION ABOUT DATA 3504 02:15:49,200 --> 02:15:53,760 REPOSITORIES PROVIDED A 3505 02:15:53,760 --> 02:15:55,640 COMPREHENSIVE MEETING AND 3506 02:15:55,640 --> 02:15:58,680 REPOSITORIES FOR DIFFERENT 3507 02:15:58,680 --> 02:15:58,920 DOMAINS. 3508 02:15:58,920 --> 02:16:01,920 AND THERE WE ACTUALLY HAVE FULL 3509 02:16:01,920 --> 02:16:03,320 REPOSITORY SUPPORTED BY NIBIB 3510 02:16:03,320 --> 02:16:07,440 THAT CURRENTLY LISTED ON THE 3511 02:16:07,440 --> 02:16:11,360 SHARING NIH.GOV THAT CAN SERVE 3512 02:16:11,360 --> 02:16:19,680 AS DOMAIN-SPECIFIC REPOSITORY 3513 02:16:19,680 --> 02:16:20,680 WHICH INCLUDING DATABASE 3514 02:16:20,680 --> 02:16:22,280 (INDISCERNIBLE) FOR SIGNAL DATA 3515 02:16:22,280 --> 02:16:24,000 AS WELL. 3516 02:16:24,000 --> 02:16:26,880 THOSE ARE THE RESOURCES THAT IS 3517 02:16:26,880 --> 02:16:29,200 ALREADY AVAILABLE AND ACTUALLY A 3518 02:16:29,200 --> 02:16:36,000 LONGTIME EFFORT OF NIBIB TO 3519 02:16:36,000 --> 02:16:40,120 DEVELOP THOSE RESOURCES THROUGH 3520 02:16:40,120 --> 02:16:45,280 R01 AND T41, IN ADDITION THESE 3521 02:16:45,280 --> 02:16:47,880 ARE JUST MINIMUM POLICY FOR 3522 02:16:47,880 --> 02:16:48,560 GENERAL ANNOUNCEMENT. 3523 02:16:48,560 --> 02:16:53,160 THERE COULD BE SPECIAL 3524 02:16:53,160 --> 02:16:53,840 ANNOUNCEMENTS, DEDICATED 3525 02:16:53,840 --> 02:16:58,000 ADDITIONAL RESOURCES FOR DATA 3526 02:16:58,000 --> 02:17:06,080 MANAGEMENT SHARING, BRIDGE TO 3527 02:17:06,080 --> 02:17:07,840 A.I., THE INITIATIVE, CO-MEETING 3528 02:17:07,840 --> 02:17:12,200 TO REALLY BOOSTING THE DATA 3529 02:17:12,200 --> 02:17:14,040 SHARING AND HEALTH CARE EQUITY 3530 02:17:14,040 --> 02:17:17,600 AND THERE MAY BE ADDITIONAL 3531 02:17:17,600 --> 02:17:19,880 INITIATIVES THAT COULD BE FOR 3532 02:17:19,880 --> 02:17:22,840 DATA AND SPECIFIC FOR THE DATA 3533 02:17:22,840 --> 02:17:28,400 MANAGEMENT AND SHARING IN THE 3534 02:17:28,400 --> 02:17:32,800 FUTURE. 3535 02:17:32,800 --> 02:17:34,320 >> THANK YOU. 3536 02:17:34,320 --> 02:17:34,600 MARYELLEN? 3537 02:17:34,600 --> 02:17:36,720 >> YES, FIRST I DID NOT SET UP 3538 02:17:36,720 --> 02:17:41,920 CYNTHIA TO ASK THAT QUESTION. 3539 02:17:41,920 --> 02:17:47,600 GREAT QUESTION, CONTACT US, 3540 02:17:47,600 --> 02:17:49,080 WE'LL WORK OUT. 3541 02:17:49,080 --> 02:17:51,720 BUT WHAT I WANTED TO SAY WITH 3542 02:17:51,720 --> 02:17:54,920 DATA SHARING IT CAN INCLUDE LIKE 3543 02:17:54,920 --> 02:17:57,080 THE TOOLS, THE SOFTWARE, 3544 02:17:57,080 --> 02:18:00,560 ALGORITHMS, THE ACTUAL DATA, AND 3545 02:18:00,560 --> 02:18:02,520 THE MACHINE INTELLIGENCE OUTPUT, 3546 02:18:02,520 --> 02:18:04,920 AND WITH THAT AS FOLKS EITHER 3547 02:18:04,920 --> 02:18:06,680 USED THEIR MACHINE INTELLIGENCE 3548 02:18:06,680 --> 02:18:08,960 AND SHARED DATA, THEIR DATA AND 3549 02:18:08,960 --> 02:18:10,600 MACHINE INTELLIGENCE ALGORITHM 3550 02:18:10,600 --> 02:18:13,680 OR OUTCOME, IT COULD FEED INTO 3551 02:18:13,680 --> 02:18:16,480 LOOKING AT BIAS AND HOW WE MIGHT 3552 02:18:16,480 --> 02:18:20,240 MITIGATE BIAS, YOU KNOW, IS THE 3553 02:18:20,240 --> 02:18:21,440 ALGORITHM THAT'S SHARED BIAS TO 3554 02:18:21,440 --> 02:18:24,280 ITS DATA WHEN YOU APPLY YOUR OWN 3555 02:18:24,280 --> 02:18:26,080 DATA FROM THAT SHARED RESOURCE 3556 02:18:26,080 --> 02:18:28,600 SO I THINK A LOT OF SECONDARY 3557 02:18:28,600 --> 02:18:30,200 USAGE WILL COME FROM THIS 3558 02:18:30,200 --> 02:18:37,200 POLICY, SO VERY SUPPORTIVE OF 3559 02:18:37,200 --> 02:18:37,360 IT. 3560 02:18:37,360 --> 02:18:39,000 >> THANK YOU. 3561 02:18:39,000 --> 02:18:39,440 >> GREAT. 3562 02:18:39,440 --> 02:18:40,960 THANK YOU SO MUCH. 3563 02:18:40,960 --> 02:18:42,040 ANY OTHER COMMENTS? 3564 02:18:42,040 --> 02:18:43,240 ZANE, I PRESUME YOUR HAND IS UP 3565 02:18:43,240 --> 02:18:43,880 FROM BEFORE. 3566 02:18:43,880 --> 02:18:50,320 DID YOU HAVE AN ADDITIONAL 3567 02:18:50,320 --> 02:18:50,560 REMARK? 3568 02:18:50,560 --> 02:18:51,680 >> MY HAND IS DOWN. 3569 02:18:51,680 --> 02:18:52,880 >> I WASN'T SURE IF YOU HAD 3570 02:18:52,880 --> 02:18:54,760 ANOTHER COMMENT. 3571 02:18:54,760 --> 02:18:59,080 HAPPY TO HEAR IT. 3572 02:18:59,080 --> 02:19:01,880 >> MAYBE I CAN KIND OF ADD SOME 3573 02:19:01,880 --> 02:19:04,520 CONNECTIONS BETWEEN A LOT OF THE 3574 02:19:04,520 --> 02:19:05,000 COMMENTS. 3575 02:19:05,000 --> 02:19:08,360 YOU KNOW, WE'RE SORT OF AT THIS 3576 02:19:08,360 --> 02:19:11,520 REALLY UNIQUE MOMENT IN TIME IN 3577 02:19:11,520 --> 02:19:13,400 TERMS OF DATA CREATION AND A LOT 3578 02:19:13,400 --> 02:19:15,960 OF THESE EFFORTS HAVE BEEN 3579 02:19:15,960 --> 02:19:17,880 DRIVEN BY THE MORE TRADITIONAL 3580 02:19:17,880 --> 02:19:20,160 BIOLOGY COMMUNITIES THAT IN 3581 02:19:20,160 --> 02:19:21,280 PARTICULAR GENOMICS WHERE 3582 02:19:21,280 --> 02:19:25,080 THERE'S BEEN HUGE SUCCESS IN 3583 02:19:25,080 --> 02:19:27,480 SHARING DATABASES FOR REUSE AND 3584 02:19:27,480 --> 02:19:28,840 CONTINUED DISCOVERY SO THERE'S 3585 02:19:28,840 --> 02:19:31,280 SUBSTANTIAL RETURN ON 3586 02:19:31,280 --> 02:19:32,280 INVESTMENT. 3587 02:19:32,280 --> 02:19:34,720 AND I THINK IT'S UP TO OUR 3588 02:19:34,720 --> 02:19:38,200 COMMUNITY TO PICK SOME CASES, IF 3589 02:19:38,200 --> 02:19:43,680 WE DO WANT -- IT IS A VERY 3590 02:19:43,680 --> 02:19:44,800 EXPENSIVE TO HAVE REPOSITORIES, 3591 02:19:44,800 --> 02:19:51,360 AND IN A SENSE WHAT THIS GUIDE 3592 02:19:51,360 --> 02:19:53,680 A NCE IS YOU NEED TO HAVE A PLAN 3593 02:19:53,680 --> 02:19:54,520 FOR DATA SHARING. 3594 02:19:54,520 --> 02:19:55,880 WE'RE NOT DICTATING YOUR PLAN 3595 02:19:55,880 --> 02:19:57,240 BUT YOU NEED TO BE THINKING 3596 02:19:57,240 --> 02:19:58,480 ABOUT IT AND ADDRESSING IT. 3597 02:19:58,480 --> 02:20:02,560 I THINK IT'S UP TO YOU GUYS TO 3598 02:20:02,560 --> 02:20:04,800 DEMONSTRATE THE VALUE OF WHEN 3599 02:20:04,800 --> 02:20:06,280 SHARING CAN DRIVE NEW DISCOVERY 3600 02:20:06,280 --> 02:20:09,680 AND DATA CAN BE REUSED IN 3601 02:20:09,680 --> 02:20:12,480 DIFFERENT WAYS ACROSS TIME. 3602 02:20:12,480 --> 02:20:14,640 AND THAT'S A BIG CHALLENGE 3603 02:20:14,640 --> 02:20:17,600 BECAUSE IF WE CAN'T REALLY SHOW 3604 02:20:17,600 --> 02:20:22,000 THAT, THEN IT'S VERY HARD TO 3605 02:20:22,000 --> 02:20:23,920 JUSTIFY FUNDING CONTINUED GROWTH 3606 02:20:23,920 --> 02:20:26,240 OF REPOSITORIES IF PEOPLE AREN'T 3607 02:20:26,240 --> 02:20:28,280 REALLY TRULY ACCESSING THEM AND 3608 02:20:28,280 --> 02:20:29,280 MAKING IMPORTANT NEW DISCOVERIES 3609 02:20:29,280 --> 02:20:31,880 THAT ARE BASED ON THEM. 3610 02:20:31,880 --> 02:20:36,240 SO, JUST IN TERMS OF 3611 02:20:36,240 --> 02:20:37,080 INVESTMENTS, INSTITUTES ARE LESS 3612 02:20:37,080 --> 02:20:40,280 LIKELY TO INVEST IN THOSE AS 3613 02:20:40,280 --> 02:20:42,040 OPPOSED TO CONTINUED GENERATION 3614 02:20:42,040 --> 02:20:45,640 OF NEW DATA SOURCES COMING FROM 3615 02:20:45,640 --> 02:20:46,160 NEW INNOVATIONS. 3616 02:20:46,160 --> 02:20:49,360 SO, THIS IS A CHALLENGE FOR OUR 3617 02:20:49,360 --> 02:20:51,280 COMMUNITY TO BRING SOME HIGH 3618 02:20:51,280 --> 02:20:53,400 PROFILE EXAMPLE CASES TO THE 3619 02:20:53,400 --> 02:20:55,920 FOREFRONT, AND THEN FROM A 3620 02:20:55,920 --> 02:20:57,720 TECHNICAL PERSPECTIVE IT STRIKES 3621 02:20:57,720 --> 02:21:00,360 ME THAT WE'RE FAIRLY INEFFICIENT 3622 02:21:00,360 --> 02:21:04,080 IN TERMS OF HOW WE BUILD DATA 3623 02:21:04,080 --> 02:21:07,240 REPOSITORIES, THE STRUCTURES, 3624 02:21:07,240 --> 02:21:08,440 AND OFTENTIMES, YOU KNOW, THE 3625 02:21:08,440 --> 02:21:12,280 KIND OF STATE OF THE ART 3626 02:21:12,280 --> 02:21:14,040 APPROACHES FOR DATA COMPRESSION 3627 02:21:14,040 --> 02:21:15,480 AND FOR MINIMIZATION OF 3628 02:21:15,480 --> 02:21:17,000 INFORMATION CONTENT TO ESSENTIAL 3629 02:21:17,000 --> 02:21:20,120 INFORMATION CONTENT MAY NOT BE 3630 02:21:20,120 --> 02:21:21,680 UTILIZED BY CERTAINLY THE 3631 02:21:21,680 --> 02:21:22,880 MORE -- THE BROADER BIOLOGY 3632 02:21:22,880 --> 02:21:23,960 COMMUNITY, AND MAYBE SOME 3633 02:21:23,960 --> 02:21:26,920 EXAMPLES OF WHAT WE DO IN THE 3634 02:21:26,920 --> 02:21:28,280 ENGINEERING AND PHYSICAL SCIENCE 3635 02:21:28,280 --> 02:21:29,280 COMMUNITY COULD INFLUENCE WHAT'S 3636 02:21:29,280 --> 02:21:33,160 GOING ON AT THE REST OF THE NIH. 3637 02:21:33,160 --> 02:21:35,040 SO I'M EAGER TO HEAR YOUR 3638 02:21:35,040 --> 02:21:36,760 THOUGHTS ABOUT THOSE APPROACHES 3639 02:21:36,760 --> 02:21:37,160 AS WELL. 3640 02:21:37,160 --> 02:21:40,600 AND WHETHER OR NOT THAT MAY HELP 3641 02:21:40,600 --> 02:21:43,360 US KEEP OR CONTAIN SOME OF THE 3642 02:21:43,360 --> 02:21:49,240 COSTS OF BUILDING THESE GIANT 3643 02:21:49,240 --> 02:21:51,280 REPOSITORIES. 3644 02:21:51,280 --> 02:21:52,680 >> THANKS, BRUCE. 3645 02:21:52,680 --> 02:21:52,880 ZANE? 3646 02:21:52,880 --> 02:21:53,960 >> BRUCE, THANKS FOR THOSE 3647 02:21:53,960 --> 02:21:54,240 COMMENTS. 3648 02:21:54,240 --> 02:21:56,880 I GUESS THE QUESTION I HAVE, IS 3649 02:21:56,880 --> 02:21:58,280 THERE ANY MEANS BY WHICH THROUGH 3650 02:21:58,280 --> 02:21:59,680 RETRO ANALYSIS OF SOME OF THE 3651 02:21:59,680 --> 02:22:01,880 WORK THAT'S BEEN DONE IN THE 3652 02:22:01,880 --> 02:22:03,880 PAST, WHERE STUDIES HAVE HAD TO 3653 02:22:03,880 --> 02:22:09,440 REPRODUCE DATA, I THINK WITH THE 3654 02:22:09,440 --> 02:22:12,720 A.I. AND M.L. EFFORTS THERE'S A 3655 02:22:12,720 --> 02:22:15,680 LOT OF WE'RE TRYING TO DEVELOP 3656 02:22:15,680 --> 02:22:16,720 SO WE DON'T DUPLICATE. 3657 02:22:16,720 --> 02:22:18,600 DO WE HAVE A BUSINESS CASE 3658 02:22:18,600 --> 02:22:20,280 ALREADY BUILT IN THIS SPACE? 3659 02:22:20,280 --> 02:22:21,480 A.I. AND M.L. AND THINGS 3660 02:22:21,480 --> 02:22:23,640 PUBLISHED IN THE PAST WHERE WE 3661 02:22:23,640 --> 02:22:25,600 SEE DUPLICATION OF EFFORT, YOU 3662 02:22:25,600 --> 02:22:26,800 KNOW, ADDITIONAL COST ASSOCIATED 3663 02:22:26,800 --> 02:22:30,000 WITH THE FACT DATA WASN'T 3664 02:22:30,000 --> 02:22:31,160 AVAILABLE? 3665 02:22:31,160 --> 02:22:33,840 3666 02:22:33,840 --> 02:22:34,800 >> I'M REALLY INTERESTED IN ALL 3667 02:22:34,800 --> 02:22:37,800 OF YOUR THOUGHTS ON THAT ONE 3668 02:22:37,800 --> 02:22:39,480 BECAUSE IT'S VERY HARD, I THINK 3669 02:22:39,480 --> 02:22:41,960 WE CAN POINT TO SEVERAL 3670 02:22:41,960 --> 02:22:43,680 EXAMPLES, PARTICULARLY IN THE 3671 02:22:43,680 --> 02:22:46,400 GENOMICS AND IN THE WHOLE 3672 02:22:46,400 --> 02:22:47,960 DISCOVERY OF THINGS LIKE 3673 02:22:47,960 --> 02:22:50,480 EPIGENETIC CLOCKS WHICH WAS ALL 3674 02:22:50,480 --> 02:22:53,680 DRIVEN BY PUBLICLY AVAILABLE 3675 02:22:53,680 --> 02:22:54,120 SHARED DATABASES. 3676 02:22:54,120 --> 02:22:58,520 BUT I'D LIKE TO SEE US DO A 3677 02:22:58,520 --> 02:23:01,440 BETTER JOB AS A COMMUNITY OF 3678 02:23:01,440 --> 02:23:04,160 SHOWING THE VALUE OF THE SHARED 3679 02:23:04,160 --> 02:23:05,800 DATA, MIDRC IS DOING IT RIGHT 3680 02:23:05,800 --> 02:23:08,280 NOW, AND BUILDING IT FROM THE 3681 02:23:08,280 --> 02:23:09,720 GROUND FLOOR SO THIS IS KIND OF 3682 02:23:09,720 --> 02:23:10,840 AN EXPERIMENT THAT MANY PEOPLE 3683 02:23:10,840 --> 02:23:16,400 ACROSS THE NIH ARE NOW WATCHING, 3684 02:23:16,400 --> 02:23:17,200 FROM THE IMAGING COMMUNITY, AND 3685 02:23:17,200 --> 02:23:21,440 SO THERE'S GOT TO BE MORE COMING 3686 02:23:21,440 --> 02:23:28,520 IN THIS SPACE. 3687 02:23:28,520 --> 02:23:32,120 >> WE CAN TALK OFFLINE, BRUCE. 3688 02:23:32,120 --> 02:23:33,000 >> YEAH. 3689 02:23:33,000 --> 02:23:34,880 A LONG DISCUSSION. 3690 02:23:34,880 --> 02:23:35,200 >> YEAH. 3691 02:23:35,200 --> 02:23:36,720 >> THANK YOU, ZANE. 3692 02:23:36,720 --> 02:23:37,280 MARYELLEN? 3693 02:23:37,280 --> 02:23:38,880 >> I'LL BE SHORT BUT I THINK 3694 02:23:38,880 --> 02:23:39,680 IT'S REALLY IMPORTANT, SINCE 3695 02:23:39,680 --> 02:23:41,720 THIS IS MY LAST MEETING I HAVE 3696 02:23:41,720 --> 02:23:47,000 TO GET MY WORDS IN. 3697 02:23:47,000 --> 02:23:50,160 I APPRECIATE BRUCE MENTIONING 3698 02:23:50,160 --> 02:23:51,880 MIDRC BECAUSE I'VE DONE A LOT OF 3699 02:23:51,880 --> 02:23:55,880 A.I. WORK IN THE LAB, YOU HAVE A 3700 02:23:55,880 --> 02:23:57,320 GREAT DATASET, ANNOTATED, AN 3701 02:23:57,320 --> 02:23:59,400 EXCEL FILE, YOU SAY, I HAVE A 3702 02:23:59,400 --> 02:24:00,080 GREAT DATABASE. 3703 02:24:00,080 --> 02:24:01,920 BUT TO USE IT AND TO REALLY 3704 02:24:01,920 --> 02:24:03,680 NAVIGATE WHERE ALL THE IMAGES 3705 02:24:03,680 --> 02:24:06,160 ARE AND TO PUT IT AT SCALE, 3706 02:24:06,160 --> 02:24:09,880 PEOPLE HAVE A LOT OF GOOD 3707 02:24:09,880 --> 02:24:13,480 DATASETS, BUT TO MOVE IT TO AT 3708 02:24:13,480 --> 02:24:14,400 SCALE, WHERE MIDRC IS, 3709 02:24:14,400 --> 02:24:15,720 THERE'S -- I'VE LEARNED A LOT. 3710 02:24:15,720 --> 02:24:19,080 HOW DO YOU SHARE THE DATA? 3711 02:24:19,080 --> 02:24:20,960 THERE'S USER AGREEMENTS. 3712 02:24:20,960 --> 02:24:21,680 CONTRIBUTING AGREEMENTS. 3713 02:24:21,680 --> 02:24:23,280 THE WHOLE AREA OF POLICY, AND 3714 02:24:23,280 --> 02:24:25,080 THEN WHAT ARE THE DATA ELEMENTS 3715 02:24:25,080 --> 02:24:27,000 ON WHICH YOU CAN SEARCH YOUR 3716 02:24:27,000 --> 02:24:29,360 DATA SO YOU CAN REUSE IT? 3717 02:24:29,360 --> 02:24:30,480 COLLECTED FOR ONE THING BUT YOU 3718 02:24:30,480 --> 02:24:33,600 HAVE TO SLICE AND DICE FOR 3719 02:24:33,600 --> 02:24:35,280 ANOTHER REUSE CASE IS A WHOLE 3720 02:24:35,280 --> 02:24:38,720 BIG DISCUSSION SO THAT YOU 3721 02:24:38,720 --> 02:24:41,080 ENABLE THAT COHORT BUILDING. 3722 02:24:41,080 --> 02:24:42,400 THERE'S ASPECTS OF JUST THE 3723 02:24:42,400 --> 02:24:45,080 RESEARCH OF USING IT AND HOW TO 3724 02:24:45,080 --> 02:24:46,920 USE IT APPROPRIATELY, WHAT 3725 02:24:46,920 --> 02:24:49,120 METRICS TO USE, HOW TO HANDLE 3726 02:24:49,120 --> 02:24:53,400 BIASES, AND THEN FOR THE 3727 02:24:53,400 --> 02:24:55,760 TRANSLATION PART HOW DO YOU 3728 02:24:55,760 --> 02:24:58,160 EXPEDITE TRANSLATION, WE DO THAT 3729 02:24:58,160 --> 02:24:59,240 WITH SEQUESTERING DATASET, BUT 3730 02:24:59,240 --> 02:25:03,040 THERE'S A LOT OF ASPECTS 3731 02:25:03,040 --> 02:25:03,960 INCLUDING CURATION AND USER 3732 02:25:03,960 --> 02:25:06,040 INTERFACE WHEN YOU MOVE A 3733 02:25:06,040 --> 02:25:09,280 DATASET AT SCALE TO TAKE IN ALL 3734 02:25:09,280 --> 02:25:10,720 THESE OTHER DATA SHARING 3735 02:25:10,720 --> 02:25:11,840 CONTRIBUTIONS, IT'S A WHOLE 3736 02:25:11,840 --> 02:25:17,480 OTHER BALL GAME THAN A DATASET 3737 02:25:17,480 --> 02:25:17,760 IN YOUR LAB. 3738 02:25:17,760 --> 02:25:19,040 A HUNDRED OF US HAVE LEARNED A 3739 02:25:19,040 --> 02:25:23,640 LOT IN THE PAST TWO YEARS. 3740 02:25:23,640 --> 02:25:25,880 >> YEAH, I THINK THE SUMMARY TO 3741 02:25:25,880 --> 02:25:28,560 ALL OF THAT IS THAT, YOU KNOW, 3742 02:25:28,560 --> 02:25:30,640 YOU'RE SHARING -- THOSE NOT A 3743 02:25:30,640 --> 02:25:32,200 POLICY THAT'S REQUIRING 3744 02:25:32,200 --> 02:25:33,680 EVERYBODY TO SHARE EVERYTHING 3745 02:25:33,680 --> 02:25:35,120 ALL THE TIME. 3746 02:25:35,120 --> 02:25:37,520 I THINK A COMMON DISCUSSION AT 3747 02:25:37,520 --> 02:25:39,880 THE NIH IS PARTICULARLY IN 3748 02:25:39,880 --> 02:25:42,320 BIOLOGY LABS, IS, HEY, WE WANT 3749 02:25:42,320 --> 02:25:43,960 EVERYBODY EVERY BIT OF DATA TO 3750 02:25:43,960 --> 02:25:47,280 BE SHARED, EVEN FAILED 3751 02:25:47,280 --> 02:25:47,560 EXPERIMENTS. 3752 02:25:47,560 --> 02:25:50,200 AND THAT'S NOT NECESSARILY IN 3753 02:25:50,200 --> 02:25:56,200 OUR CULTURE, YOU KNOW, AS QI 3754 02:25:56,200 --> 02:25:58,480 POINTED OUT FROM BIOLOGY DRIVEN 3755 02:25:58,480 --> 02:25:59,080 VERSUS TECHNOLOGY RESEARCH, 3756 02:25:59,080 --> 02:26:02,400 MAYBE THINGS THAT GO ON IN OUR 3757 02:26:02,400 --> 02:26:03,840 COMMUNITY ARE TECHNOLOGY DRIVEN 3758 02:26:03,840 --> 02:26:06,560 AND FAILED EXPERIMENTS ARE 3759 02:26:06,560 --> 02:26:08,320 TECHNOLOGIES THAT YOU JUST -- 3760 02:26:08,320 --> 02:26:10,280 THEY SEEMED LIKE A GOOD IDEA, NO 3761 02:26:10,280 --> 02:26:12,480 ONE IS GOING TO PURSUE THEM. 3762 02:26:12,480 --> 02:26:16,280 SOMETIMES THEY TEND TO GET 3763 02:26:16,280 --> 02:26:18,440 COMMUNICATED OR SHARED THROUGH 3764 02:26:18,440 --> 02:26:18,960 PRESENTATIONS BY TRAINEES, 3765 02:26:18,960 --> 02:26:20,120 CONFERENCES WHO SAY WE TRIED 3766 02:26:20,120 --> 02:26:21,440 THIS, TRIED THIS, TRIED THIS. 3767 02:26:21,440 --> 02:26:23,560 SO WE HAVE TO THINK LOGICALLY 3768 02:26:23,560 --> 02:26:27,000 ABOUT THE SCALE OF THE PROBLEM 3769 02:26:27,000 --> 02:26:29,120 AND THE OPPORTUNITIES, MIDRC IS 3770 02:26:29,120 --> 02:26:30,400 AN AMAZING EXAMPLE OF THE KIND 3771 02:26:30,400 --> 02:26:33,880 OF HUGE IMPACT THAT WE CAN HAVE 3772 02:26:33,880 --> 02:26:36,440 IN SHARING THAT IS IMMEDIATELY 3773 02:26:36,440 --> 02:26:39,480 UNDERSTANDABLE BY THE SORT OF 3774 02:26:39,480 --> 02:26:44,440 MAINSTREAM BIOLOGY, BIOMEDICAL 3775 02:26:44,440 --> 02:26:46,240 COMMUNITY BUT WE DON'T WANT TO 3776 02:26:46,240 --> 02:26:49,240 BE WEDGED INTO THAT MODEL FOR 3777 02:26:49,240 --> 02:26:50,040 EVERYBODY'S RESEARCH, EVERY R01, 3778 02:26:50,040 --> 02:26:51,720 AND IT NEEDS TO BE APPROPRIATE 3779 02:26:51,720 --> 02:26:53,960 GIVEN THE SCALE AND THE SIZE OF 3780 02:26:53,960 --> 02:26:59,080 THE WORK AND THE AMBITION. 3781 02:26:59,080 --> 02:27:01,800 3782 02:27:01,800 --> 02:27:05,320 >> THANK YOU. 3783 02:27:05,320 --> 02:27:06,160 ANY OTHER FINAL COMMENTS? 3784 02:27:06,160 --> 02:27:09,760 BRUCE, WOULD YOU LIKE TO MOVE TO 3785 02:27:09,760 --> 02:27:12,280 THE NEXT SEGMENT? 3786 02:27:12,280 --> 02:27:14,360 >> YES, AND WE REALLY TEED THIS 3787 02:27:14,360 --> 02:27:23,120 UP WITH STEPHANIE AND LUISA, I 3788 02:27:23,120 --> 02:27:24,080 THINK WITH OUR RADxIFICATION 3789 02:27:24,080 --> 02:27:28,560 DISCUSSION, AND THEY ARE THE 3790 02:27:28,560 --> 02:27:30,080 SOFTWARE MATERIALS EXPERTS, A 3791 02:27:30,080 --> 02:27:30,880 TERRIFIC INNOVATIVE IDEA TO 3792 02:27:30,880 --> 02:27:33,960 SHARE WITH ALL OF YOU. 3793 02:27:33,960 --> 02:27:35,520 STEPHANIE AND LUISA, TAKE IT 3794 02:27:35,520 --> 02:27:35,800 AWAY. 3795 02:27:35,800 --> 02:27:39,200 >> THANK YOU, BRUCE. 3796 02:27:39,200 --> 02:27:47,400 LIT LET ME SHARE MY SCREEN. 3797 02:27:47,400 --> 02:27:50,920 YOU SHOULD BE ABLE TO SEE THE 3798 02:27:50,920 --> 02:27:55,040 TITLE SLIDE FOR TODAY'S 3799 02:27:55,040 --> 02:27:55,440 PRESENTATION. 3800 02:27:55,440 --> 02:27:55,880 OKAY. 3801 02:27:55,880 --> 02:27:57,680 AGAIN, THANK YOU FOR THE 3802 02:27:57,680 --> 02:27:58,480 INTRODUCTION. 3803 02:27:58,480 --> 02:28:00,960 I'M HERE TO PRESENT A CONCEPT ON 3804 02:28:00,960 --> 02:28:03,400 BEHALF OF THE DIVISION OF 3805 02:28:03,400 --> 02:28:05,280 DISCOVERY SCIENCE AND 3806 02:28:05,280 --> 02:28:06,440 TECHNOLOGY, DDST. 3807 02:28:06,440 --> 02:28:08,080 I'M STEPHANIE MORRIS, I WAS 3808 02:28:08,080 --> 02:28:10,680 RECENTLY ON A PART TIME DETAIL 3809 02:28:10,680 --> 02:28:12,240 WITHIN THIS DIVISION FOR EIGHT 3810 02:28:12,240 --> 02:28:15,520 MONTHS, MY HOME BASE ACTUALLY IS 3811 02:28:15,520 --> 02:28:16,640 HUMAN GENOME RESEARCH INSTITUTE 3812 02:28:16,640 --> 02:28:19,480 WHERE I'M A PROGRAM DIRECTOR, 3813 02:28:19,480 --> 02:28:29,040 MANAGING EFFORTS IN TECHNOLOGY 3814 02:28:29,040 --> 02:28:30,480 DEVELOPMENT AND FUNCTIONAL 3815 02:28:30,480 --> 02:28:30,760 GENOMICS. 3816 02:28:30,760 --> 02:28:33,680 YOU'LL HEAR FROM ME AND LUISA 3817 02:28:33,680 --> 02:28:37,280 RUSSELL, PROGRAM DIRECTOR IN 3818 02:28:37,280 --> 02:28:38,800 DDST, WE'VE BEEN WORKING 3819 02:28:38,800 --> 02:28:40,520 TOGETHER ON THIS PROGRAM CONCEPT 3820 02:28:40,520 --> 02:28:44,160 OVER THE PAST SEVERAL MONTHS, 3821 02:28:44,160 --> 02:28:45,680 ALONG WITH THE DIRECTOR, IT'S 3822 02:28:45,680 --> 02:28:47,720 BEEN A FANTASTIC OPPORTUNITY TO 3823 02:28:47,720 --> 02:28:49,600 WORK WITH THEM. 3824 02:28:49,600 --> 02:28:51,880 SO THE TENTATIVE LONG HAND NAME 3825 02:28:51,880 --> 02:28:54,640 FOR THE PROGRAM IS BIOMATERIALS 3826 02:28:54,640 --> 02:28:56,000 TECHNOLOGY RESOURCE AND 3827 02:28:56,000 --> 02:28:56,440 INTEGRATION NETWORK. 3828 02:28:56,440 --> 02:28:57,680 AND THAT NAME IS THERE BECAUSE 3829 02:28:57,680 --> 02:28:59,520 WE WANT TO BE CONSISTENT WITH 3830 02:28:59,520 --> 02:29:02,280 THE NAMING CONVENTION OF OTHER 3831 02:29:02,280 --> 02:29:04,520 NETWORKS SUPPORTED BY NIBIB. 3832 02:29:04,520 --> 02:29:10,280 WE'RE CALLING IT THE 3833 02:29:10,280 --> 02:29:12,680 BIOMATERIALS NETWORK, FOR SHORT. 3834 02:29:12,680 --> 02:29:14,520 RATIONALE FOR WHY THIS IS 3835 02:29:14,520 --> 02:29:17,160 BROUGHT TO YOU TODAY, THIS IS 3836 02:29:17,160 --> 02:29:21,640 REALLY ABOUT BROADLY ADDRESSING 3837 02:29:21,640 --> 02:29:22,480 CHALLENGES TO TECHNOLOGY 3838 02:29:22,480 --> 02:29:24,160 TRANSLATION HOMING IN ON 3839 02:29:24,160 --> 02:29:26,480 BIOMATERIALS IN PARTICULAR. 3840 02:29:26,480 --> 02:29:28,320 IT'S BEEN A WONDERFUL MORNING, 3841 02:29:28,320 --> 02:29:32,760 SO FAR, TEEING UP FOR THIS 3842 02:29:32,760 --> 02:29:34,080 PRESENTATION. 3843 02:29:34,080 --> 02:29:36,400 SO, AS YOU KNOW, THE ITERATIVE 3844 02:29:36,400 --> 02:29:38,360 PROCESS CAN AFFECT DESIGN AND 3845 02:29:38,360 --> 02:29:39,800 PROGRESS OF DEVELOPMENT. 3846 02:29:39,800 --> 02:29:43,080 GOING FROM INNOVATIVE IDEA TO 3847 02:29:43,080 --> 02:29:45,680 CLINICAL APPLICATION IS NOT 3848 02:29:45,680 --> 02:29:45,880 TRIVIAL. 3849 02:29:45,880 --> 02:29:49,040 TIME AND PATHWAY TO GET TO THE 3850 02:29:49,040 --> 02:29:55,360 CLINIC IS COMPLEX, EXTENSIVE, 3851 02:29:55,360 --> 02:29:58,000 DEVELOPERS ENCOUNTER HURDLES CAN 3852 02:29:58,000 --> 02:29:58,520 RESULT IN TECHNOLOGIES 3853 02:29:58,520 --> 02:30:06,080 LANGUISHING IN THE VALLEY OF 3854 02:30:06,080 --> 02:30:06,840 DEATH. 3855 02:30:06,840 --> 02:30:07,480 THINGS LIKE REPRODUCIBILITY, 3856 02:30:07,480 --> 02:30:09,480 VALIDATION, NEED FOR THAT. 3857 02:30:09,480 --> 02:30:10,440 MATCHING AND TECHNOLOGY 3858 02:30:10,440 --> 02:30:11,680 CAPABILITIES WITH MARKET AND 3859 02:30:11,680 --> 02:30:13,400 CLINICAL NEED. 3860 02:30:13,400 --> 02:30:14,920 HAVING A SUPPORTIVE ACADEMIC 3861 02:30:14,920 --> 02:30:17,840 INSTITUTION AND IN GENERAL 3862 02:30:17,840 --> 02:30:18,520 HAVING SUPPORTIVE DIFFERENT 3863 02:30:18,520 --> 02:30:23,000 STAGES OF DEVELOPMENT. 3864 02:30:23,000 --> 02:30:25,080 IMPORTANCE OF INTELLECTUAL 3865 02:30:25,080 --> 02:30:25,560 PROPERTY CONSIDERATION, 3866 02:30:25,560 --> 02:30:26,960 DEVELOPING COLLABORATIONS AS 3867 02:30:26,960 --> 02:30:29,480 WELL AS TIMING, RISK, COST. 3868 02:30:29,480 --> 02:30:31,160 FOR THIS PROGRAM, IT'S FOCUSED 3869 02:30:31,160 --> 02:30:35,800 ON PROVIDING SUPPORT TO HELP 3870 02:30:35,800 --> 02:30:36,720 NIBIB TECH DEVELOPMENTS TRAVERSE 3871 02:30:36,720 --> 02:30:39,480 VALLEY OF DEATH TO GET TO POINT 3872 02:30:39,480 --> 02:30:42,360 OF ADOPTION OF TECHNOLOGY, 3873 02:30:42,360 --> 02:30:43,920 DISSEMINATION TO BROADER 3874 02:30:43,920 --> 02:30:44,200 COMMUNITY. 3875 02:30:44,200 --> 02:30:48,200 WHY DO WE NEED BIOMATERIALS 3876 02:30:48,200 --> 02:30:48,440 NETWORK? 3877 02:30:48,440 --> 02:30:50,280 BIOMATERIALS ARE SUPPORTED 3878 02:30:50,280 --> 02:30:55,520 ACROSS THE NIH, AT STAGES WHERE 3879 02:30:55,520 --> 02:30:56,560 THEY FIT THE MISSION. 3880 02:30:56,560 --> 02:30:58,640 WHAT WE DO NEED IS TO REDUCE 3881 02:30:58,640 --> 02:31:00,840 NUMBER OF ISSUES THAT DEVELOPERS 3882 02:31:00,840 --> 02:31:03,680 ENCOUNTER IN PROJECTS BY 3883 02:31:03,680 --> 02:31:05,440 ADDRESSING EARLY STAGES NEW 3884 02:31:05,440 --> 02:31:06,280 BIOMATERIALS TECHNOLOGY 3885 02:31:06,280 --> 02:31:06,560 DEVELOPMENT. 3886 02:31:06,560 --> 02:31:07,920 THIS WOULD BE DURING THE STAGES 3887 02:31:07,920 --> 02:31:10,280 OF DEVELOPMENT PRIOR TO WHEN 3888 02:31:10,280 --> 02:31:12,320 THEY START TO TARGET SPECIFIC 3889 02:31:12,320 --> 02:31:14,280 APPLICATIONS AND PROBLEMS. 3890 02:31:14,280 --> 02:31:17,880 OUR EXAMPLE, CASE STUDY FOR 3891 02:31:17,880 --> 02:31:20,280 BIOMATERIALS IS BIOMATERIALS 3892 02:31:20,280 --> 02:31:21,720 SPACE THERAPEUTICS, RECENT 3893 02:31:21,720 --> 02:31:24,640 REVIEW EXAMINED WHY SOME 3894 02:31:24,640 --> 02:31:27,000 MEDICINES FAIL TO BE TRANSLATED, 3895 02:31:27,000 --> 02:31:28,280 IDENTIFIED THREE BOTTLENECKS 3896 02:31:28,280 --> 02:31:31,000 THAT CAN PREVENT CROSSING VALLEY 3897 02:31:31,000 --> 02:31:34,120 OF DEATH, THESE ARE SCIENCE, 3898 02:31:34,120 --> 02:31:34,840 MARKET, CLINIC. 3899 02:31:34,840 --> 02:31:37,240 TAKING A QUICK LOOK AT EACH, 3900 02:31:37,240 --> 02:31:38,080 THERE ARE SEVERAL CHALLENGES 3901 02:31:38,080 --> 02:31:41,920 THAT CROP UP NOT LIMITED TO 3902 02:31:41,920 --> 02:31:45,320 NANOMEDICINES OR THERAPEUTICS. 3903 02:31:45,320 --> 02:31:46,520 IN SCIENCE, UNDERSTANDING 3904 02:31:46,520 --> 02:31:47,960 MATERIALS WITH BIOLOGICAL 3905 02:31:47,960 --> 02:31:48,840 TISSUES, CHALLENGES TO 3906 02:31:48,840 --> 02:31:51,360 MANUFACTURING, THINKING ABOUT 3907 02:31:51,360 --> 02:32:02,040 THE SCALING UP PROCESS, MATERIAL 3908 02:32:02,040 --> 02:32:04,840 SAFETY ISSUES, IN CLINIC 3909 02:32:04,840 --> 02:32:07,080 DIFFICULTY IN SECURING FUNDS. 3910 02:32:07,080 --> 02:32:11,440 WE'RE DESIGNING TO ADDRESS 3911 02:32:11,440 --> 02:32:12,880 BOTTLENECKS, NOT ABOUT HAVING 3912 02:32:12,880 --> 02:32:14,080 RESOURCES BUT HAVING THE RIGHT 3913 02:32:14,080 --> 02:32:17,000 RESOURCES AT THE RIGHT TIME WITH 3914 02:32:17,000 --> 02:32:18,680 SPECIFIC SUPPORT ALONG EACH STEP 3915 02:32:18,680 --> 02:32:23,800 OF THE PATH BENCH TO BEDSIDE. 3916 02:32:23,800 --> 02:32:25,320 MOVING ALONG WITH THIS NETWORK 3917 02:32:25,320 --> 02:32:26,680 WE'RE PREPARING TO SUPPORT 3918 02:32:26,680 --> 02:32:29,120 ENGINEERING OF BIOMATERIALS IN A 3919 02:32:29,120 --> 02:32:31,280 DIFFERENT WAY THAN SEEN IN OTHER 3920 02:32:31,280 --> 02:32:31,480 I.C.s. 3921 02:32:31,480 --> 02:32:35,640 CURRENT MODEL LARGELY IN USE AT 3922 02:32:35,640 --> 02:32:51,000 NIBIB, ACROSS NIH, BIOLOGICAL 3923 02:32:51,000 --> 02:32:51,720 FOR BIOMATERIALS SUPPORTED 3924 02:32:51,720 --> 02:32:54,000 ACROSS NIH ARE AT THE STAGE 3925 02:32:54,000 --> 02:32:57,760 WHERE MAJORITY ARE WELL ACCEPTED 3926 02:32:57,760 --> 02:32:59,120 TOOLS, BIOMATERIALS, AND 3927 02:32:59,120 --> 02:33:01,280 TAILORED TO CERTAIN CLINICAL 3928 02:33:01,280 --> 02:33:06,080 APPLICATIONS, RESPONSIVE TO 3929 02:33:06,080 --> 02:33:08,280 MISSION OF THAT INSTITUTE, 3930 02:33:08,280 --> 02:33:10,000 PRIMED TO ADDRESS SPECIFIC 3931 02:33:10,000 --> 02:33:10,840 PROBLEMS. 3932 02:33:10,840 --> 02:33:15,680 AT NIBIB WE'RE FOCUSED ON NOVEL 3933 02:33:15,680 --> 02:33:17,480 CLASSES WITH BROAD APPLICABILITY 3934 02:33:17,480 --> 02:33:19,640 ACROSS CLINICAL AREAS, EARLY 3935 02:33:19,640 --> 02:33:21,480 STAGES PRIOR TO TAILORING PHASE. 3936 02:33:21,480 --> 02:33:23,800 THE INTENTION OF THE 3937 02:33:23,800 --> 02:33:25,960 BIOMATERIALS NETWORK IS TO 3938 02:33:25,960 --> 02:33:27,800 PROVIDE NIBIB BIOMATERIALS TECH 3939 02:33:27,800 --> 02:33:28,920 DEVELOPERS ACCESS TO EXPERTISE 3940 02:33:28,920 --> 02:33:31,000 AND SUPPORT ALONG THE 3941 02:33:31,000 --> 02:33:32,960 DEVELOPMENT PIPELINE TO REALLY 3942 02:33:32,960 --> 02:33:35,640 HONE CAPABILITIES OF THESE 3943 02:33:35,640 --> 02:33:38,160 TECHNOLOGIES AND ACCELERATE 3944 02:33:38,160 --> 02:33:38,480 TRANSLATION. 3945 02:33:38,480 --> 02:33:41,080 WE WANT TO POINT OUT THAT THIS 3946 02:33:41,080 --> 02:33:43,880 PROGRAM IS BUILDING UPON AND 3947 02:33:43,880 --> 02:33:46,280 LEVERAGING ACCEPTANCE OF SOME 3948 02:33:46,280 --> 02:33:48,360 TECHNOLOGY DEVELOPMENT PROGRAMS 3949 02:33:48,360 --> 02:33:54,920 HERE AT NIH, LIKE POCTRN, NIH'S 3950 02:33:54,920 --> 02:33:58,560 MICROANALYSIS AND TECHNOLOGIES 3951 02:33:58,560 --> 02:33:59,920 PROGRAM, AND GENOME TECHNOLOGY 3952 02:33:59,920 --> 02:34:00,360 PROGRAM. 3953 02:34:00,360 --> 02:34:02,560 SO THERE ARE THREE GOALS FOR 3954 02:34:02,560 --> 02:34:05,480 THIS NETWORK THAT WE WANT TO 3955 02:34:05,480 --> 02:34:06,840 HIGHLIGHT TODAY. 3956 02:34:06,840 --> 02:34:14,120 THAT INCLUDES DEVELOPING A 3957 02:34:14,120 --> 02:34:15,760 PIPELINE OF BIOMATERIALS, WE 3958 02:34:15,760 --> 02:34:17,440 WANT THIS TO PROVIDE EXPERTISE 3959 02:34:17,440 --> 02:34:19,720 IN RESOURCES TO PROVIDE 3960 02:34:19,720 --> 02:34:22,560 FOUNDATION TO OVERCOME FUTURE 3961 02:34:22,560 --> 02:34:22,920 IMPLEMENTATION. 3962 02:34:22,920 --> 02:34:26,120 AND LASTLY, WE WANT TO ENABLE 3963 02:34:26,120 --> 02:34:26,680 TARGETED COLLABORATIONS TO 3964 02:34:26,680 --> 02:34:27,840 ENHANCE TECHNOLOGY DEVELOPMENT. 3965 02:34:27,840 --> 02:34:30,080 THIS WOULD BE WITHIN THE NETWORK 3966 02:34:30,080 --> 02:34:32,080 AND ACROSS NIH AT EARLY AND 3967 02:34:32,080 --> 02:34:32,880 ADVANCED STAGES. 3968 02:34:32,880 --> 02:34:34,480 I'LL STOP HERE AND TURN IT OVER 3969 02:34:34,480 --> 02:34:37,600 TO LUISA TO TALK MORE ABOUT THE 3970 02:34:37,600 --> 02:34:40,680 ACTUAL CONCEPT AND DETAILS. 3971 02:34:40,680 --> 02:34:44,520 >> ALL RIGHT. 3972 02:34:44,520 --> 02:34:46,480 THANK YOU, STEPHANIE. 3973 02:34:46,480 --> 02:34:48,360 OVERALL CONCEPT IS TO BUILD A 3974 02:34:48,360 --> 02:34:50,240 FRAMEWORK AROUND THE EXCITING 3975 02:34:50,240 --> 02:34:54,480 WORK IN THE DDST BIOMATERIALS 3976 02:34:54,480 --> 02:34:57,600 PORTFOLIO. 3977 02:34:57,600 --> 02:34:58,760 WHAT MAKES THIS DIFFERENT IS 3978 02:34:58,760 --> 02:34:59,880 THAT WE'RE MEETING P.I.s WHERE 3979 02:34:59,880 --> 02:35:02,560 THEY ARE IN THE EARLY STAGES OF 3980 02:35:02,560 --> 02:35:03,120 TECHNOLOGY DEVELOPMENT WHERE 3981 02:35:03,120 --> 02:35:05,480 PEOPLE OFTEN DON'T HAVE THE 3982 02:35:05,480 --> 02:35:06,480 PARTNERSHIPS OR RESOURCES TO 3983 02:35:06,480 --> 02:35:08,760 ADDRESS LATE STAGE CONCERNS THEY 3984 02:35:08,760 --> 02:35:11,600 WOULD BENEFIT FROM CONSIDERING 3985 02:35:11,600 --> 02:35:11,840 EARLIER. 3986 02:35:11,840 --> 02:35:13,080 BASICALLY WE'RE TAKING NOVEL 3987 02:35:13,080 --> 02:35:14,680 BIOMATERIALS AT NIBIB AND MAKING 3988 02:35:14,680 --> 02:35:16,240 SURE WHEN WE FUND DEVELOPMENT WE 3989 02:35:16,240 --> 02:35:17,360 GET MORE SUCCESS OUT OF WHAT IS 3990 02:35:17,360 --> 02:35:18,640 PROPOSED BECAUSE THE P.I.s 3991 02:35:18,640 --> 02:35:20,280 WILL HAVE ACCESS TO THE RIGHT 3992 02:35:20,280 --> 02:35:22,240 RESOURCES AT THE RIGHT TIMES. 3993 02:35:22,240 --> 02:35:23,960 TO ACCOMPLISH THAT WE PROPOSE 3994 02:35:23,960 --> 02:35:26,240 SET OF SUPPORTING NETWORK 3995 02:35:26,240 --> 02:35:26,840 CENTERS ALONGSIDE TECHNOLOGY 3996 02:35:26,840 --> 02:35:27,680 DRIVEN PROJECTS, I'LL JUMP INTO 3997 02:35:27,680 --> 02:35:30,720 THE DETAILS OF EACH OF THESE 3998 02:35:30,720 --> 02:35:32,080 COMPONENTS NOW. 3999 02:35:32,080 --> 02:35:34,280 THE NEXT WORK CENTERS INCLUDE 4000 02:35:34,280 --> 02:35:35,920 TECHNOLOGY COORDINATION CENTER 4001 02:35:35,920 --> 02:35:37,040 AND TECHNOLOGY RESOURCES CENTER, 4002 02:35:37,040 --> 02:35:38,240 AND THESE ARE DESIGNED TO WORK 4003 02:35:38,240 --> 02:35:39,760 TOGETHER TO SUPPORT DESIGN AND 4004 02:35:39,760 --> 02:35:42,560 TRANSLATIONAL NEEDS OF THE 4005 02:35:42,560 --> 02:35:45,280 TECHNOLOGY DEVELOPMENT PROJECTS. 4006 02:35:45,280 --> 02:35:46,520 TECHNOLOGY COORDINATION AND 4007 02:35:46,520 --> 02:35:48,280 INTEGRATION CENTERS FOCUSES ON 4008 02:35:48,280 --> 02:35:50,040 EFFORTS SUPPORTED BY THE 4009 02:35:50,040 --> 02:35:50,280 NETWORK. 4010 02:35:50,280 --> 02:35:52,080 TECHNOLOGY RESOURCES CENTER WILL 4011 02:35:52,080 --> 02:35:53,640 AID IN TECHNOLOGY DEVELOPMENT 4012 02:35:53,640 --> 02:35:55,320 PROCESS BY PROVIDING EXPERTISE 4013 02:35:55,320 --> 02:35:56,960 AND RESOURCES TO ADDRESS 4014 02:35:56,960 --> 02:35:58,640 BARRIERS TO TECHNOLOGY 4015 02:35:58,640 --> 02:35:59,480 DISSEMINATION AND TRANSLATION. 4016 02:35:59,480 --> 02:36:02,680 BOTH CENTERS WILL WORK TOGETHER 4017 02:36:02,680 --> 02:36:04,960 TO PROVIDE OPPORTUNITIES FOR 4018 02:36:04,960 --> 02:36:09,320 PARTNERING, COORDINATION SUCH AS 4019 02:36:09,320 --> 02:36:10,280 ENTREPRENEURIAL TRAINING, 4020 02:36:10,280 --> 02:36:12,760 TECHNICAL COMMERCIALIZATION AND 4021 02:36:12,760 --> 02:36:14,280 TRANSLATIONAL EXPERTISE AND 4022 02:36:14,280 --> 02:36:14,600 RESOURCES. 4023 02:36:14,600 --> 02:36:15,680 IMPORTANTLY, THEY WILL PROVIDE 4024 02:36:15,680 --> 02:36:18,080 ACCESS TO OPPORTUNITY FUNDS IN 4025 02:36:18,080 --> 02:36:19,680 RESPONSE TO DESIGN, CLINICAL, 4026 02:36:19,680 --> 02:36:22,680 TECHNICAL NEEDS IDENTIFIED IN 4027 02:36:22,680 --> 02:36:25,520 THE CENTER'S ASSESSMENT OF 4028 02:36:25,520 --> 02:36:26,920 TECHNOLOGIES. 4029 02:36:26,920 --> 02:36:31,080 WE PROPOSE TWO TO BE SUPPORTED, 4030 02:36:31,080 --> 02:36:33,160 EXPLORATORY AND PROTOTYPING. 4031 02:36:33,160 --> 02:36:35,280 EXPLORATORIES ARE PROOF OF 4032 02:36:35,280 --> 02:36:36,560 PRINCIPLES EARLY STAGE 4033 02:36:36,560 --> 02:36:38,480 ENGINEERING PROJECTS, FOCUSING 4034 02:36:38,480 --> 02:36:39,280 ON DEVELOPMENT OF EMERGING 4035 02:36:39,280 --> 02:36:40,840 BIOMATERIALS TECHNOLOGIES. 4036 02:36:40,840 --> 02:36:42,520 SINCE THE BIOMATERIALS PORTFOLIO 4037 02:36:42,520 --> 02:36:45,680 AT NIBIB IS DISEASE AND PLATFORM 4038 02:36:45,680 --> 02:36:47,160 AGNOSTIC THESE COULD INCLUDE 4039 02:36:47,160 --> 02:36:51,440 NOVEL VARIATIONS ON EXISTING 4040 02:36:51,440 --> 02:36:55,160 MATERIALS CLASSES TO EXPLORATION 4041 02:36:55,160 --> 02:36:56,800 OF BIOMEDICAL OR PERSONALIZED 4042 02:36:56,800 --> 02:36:57,320 DELIVERY SYSTEMS. 4043 02:36:57,320 --> 02:37:01,200 ON THE OTHER HAND THE 4044 02:37:01,200 --> 02:37:02,160 PROTOTYPING PROJECT DESIGNS 4045 02:37:02,160 --> 02:37:03,280 BIOMEDICAL PROOF-OF-CONCEPT 4046 02:37:03,280 --> 02:37:04,680 THROUGH EARLY STAGE VALIDATION, 4047 02:37:04,680 --> 02:37:06,000 INCLUDING PROJECTS FOCUSED ON 4048 02:37:06,000 --> 02:37:10,360 DEVELOPMENT OF NOVEL BIOMEDICAL 4049 02:37:10,360 --> 02:37:11,680 PLATFORMS BASED ON CLASSES THAT 4050 02:37:11,680 --> 02:37:14,440 EXIST OR HAVE BEEN DEVELOPED 4051 02:37:14,440 --> 02:37:16,280 THROUGH THE EXPLORATORY PROJECT. 4052 02:37:16,280 --> 02:37:17,960 BOTH EXPLORATORY AND PROTOTYPING 4053 02:37:17,960 --> 02:37:21,080 PROJECTS ARE DESIGNED TO BE 4054 02:37:21,080 --> 02:37:22,360 MILESTONE DRIVEN WORKING WITH 4055 02:37:22,360 --> 02:37:24,040 CENTRAL RESOURCES. 4056 02:37:24,040 --> 02:37:28,920 WE PLAN TO LEVERAGE R21 AND 4057 02:37:28,920 --> 02:37:30,480 R01s, BOTH EXPLORATORY AND 4058 02:37:30,480 --> 02:37:31,800 PROTOTYPING PROJECTS ARE 4059 02:37:31,800 --> 02:37:35,560 DIFFERENT FROM THE PARENT R01, 4060 02:37:35,560 --> 02:37:36,680 R21, R21 TRAILBLAZER WE SUPPORT 4061 02:37:36,680 --> 02:37:39,240 BECAUSE OF THEIR HIGH LEVEL OF 4062 02:37:39,240 --> 02:37:40,760 INTEGRATION WITH SCIENTIFIC, 4063 02:37:40,760 --> 02:37:41,520 CLINICAL, MARKET-BASED RESOURCES 4064 02:37:41,520 --> 02:37:44,280 EARLY ON IN DEVELOPMENT AS WELL 4065 02:37:44,280 --> 02:37:45,640 AS ADDITION OF MILESTONING TO 4066 02:37:45,640 --> 02:37:46,360 ENSURE PROGRESS. 4067 02:37:46,360 --> 02:37:47,840 ALL OF THESE NETWORK COMPONENTS 4068 02:37:47,840 --> 02:37:50,160 HAVE BEEN DESIGNED TO WORK 4069 02:37:50,160 --> 02:37:56,760 TOGETHER TO ADDRESS GAPS FOR 4070 02:37:56,760 --> 02:38:00,480 TRANSLATION OF BIOMATERIALS. 4071 02:38:00,480 --> 02:38:03,480 NEXT SLIDE PLEASE. 4072 02:38:03,480 --> 02:38:06,520 KEY FEATURE IS THIS INTERACTION 4073 02:38:06,520 --> 02:38:08,320 BETWEEN CENTERS AND PROJECTS. 4074 02:38:08,320 --> 02:38:10,840 THE NETWORK CENTER SHOULD 4075 02:38:10,840 --> 02:38:12,560 PROVIDE RESOURCES INCLUDING 4076 02:38:12,560 --> 02:38:13,480 SCIENTIFIC, CLINICAL, 4077 02:38:13,480 --> 02:38:14,560 REGULATORY, MARKET BASED 4078 02:38:14,560 --> 02:38:16,600 CONSULTANTS AS WELL AS RESOURCES 4079 02:38:16,600 --> 02:38:18,840 IN MODELING, EDUCATION AND 4080 02:38:18,840 --> 02:38:19,160 DESIGN. 4081 02:38:19,160 --> 02:38:20,680 CENTERS WILL IDENTIFY AND BUILD 4082 02:38:20,680 --> 02:38:21,880 PARTNERSHIPS TO BENEFIT 4083 02:38:21,880 --> 02:38:24,560 DEVELOPMENT OF TECHNOLOGIES IN 4084 02:38:24,560 --> 02:38:26,080 THE EXPLORATORY AND PROTOTYPING 4085 02:38:26,080 --> 02:38:26,360 PROJECTS. 4086 02:38:26,360 --> 02:38:28,880 IN ADDITION, CENTERS WILL BE 4087 02:38:28,880 --> 02:38:29,400 RESPONSIBLE FOR ASSESSING 4088 02:38:29,400 --> 02:38:30,840 TECHNOLOGY DEVELOPMENT PROJECTS 4089 02:38:30,840 --> 02:38:32,280 FOR NEEDS AND UTILIZATION OF 4090 02:38:32,280 --> 02:38:34,360 RESOURCES, AND WHEN STUDIES ARE 4091 02:38:34,360 --> 02:38:35,880 RECOMMENDED THAT WERE NOT 4092 02:38:35,880 --> 02:38:37,520 PROPOSED OR BUDGETED FOR NETWORK 4093 02:38:37,520 --> 02:38:40,960 CENTERS WILL HAVE ABILITY TO 4094 02:38:40,960 --> 02:38:41,800 SOLICIT AND ADMINISTER 4095 02:38:41,800 --> 02:38:43,560 OPPORTUNITY FUNDS INCLUDING USE 4096 02:38:43,560 --> 02:38:47,680 OF INDUSTRY STANDARDS, 4097 02:38:47,680 --> 02:38:49,800 VALIDATION STUDS THROUGH 4098 02:38:49,800 --> 02:38:50,400 PARTNERSHIPS. 4099 02:38:50,400 --> 02:38:51,000 TECHNOLOGY DEVELOPMENT PROJECT 4100 02:38:51,000 --> 02:38:52,920 ARE REQUIRED TO WORK WITH THE 4101 02:38:52,920 --> 02:38:55,520 CENTERS, WITH ABILITY TO TAKE 4102 02:38:55,520 --> 02:38:57,160 ADVANTAGE OF TECHNICAL, 4103 02:38:57,160 --> 02:38:57,800 TRANSLATIONAL, COMMERCIALIZATION 4104 02:38:57,800 --> 02:39:00,800 CONSULTANTS AS NEEDED AS WELL AS 4105 02:39:00,800 --> 02:39:01,880 AFOREMENTIONED RESOURCE. 4106 02:39:01,880 --> 02:39:03,960 NOT ONLY THAT BUT BOTH 4107 02:39:03,960 --> 02:39:04,600 EXPLORATORY AND PROTOTYPING 4108 02:39:04,600 --> 02:39:06,120 PROJECTS ARE SUBJECT TO NEEDS 4109 02:39:06,120 --> 02:39:08,560 ASSESSMENT BY CENTERS OF REGULAR 4110 02:39:08,560 --> 02:39:12,600 INTERVALS ENSURING THEY TAKE 4111 02:39:12,600 --> 02:39:13,600 ADVANTAGE OF RESOURCES AVAILABLE 4112 02:39:13,600 --> 02:39:15,240 APPROPRIATE TO THE STAGE THEY 4113 02:39:15,240 --> 02:39:22,880 ARE AT.. 4114 02:39:22,880 --> 02:39:24,280 BOTH CENTERS AND TECHNOLOGY 4115 02:39:24,280 --> 02:39:25,400 DEVELOPMENT PROJECTS WILL ATTEND 4116 02:39:25,400 --> 02:39:28,040 ANNUAL P.I. MEETING AND AD HOC 4117 02:39:28,040 --> 02:39:29,000 WORKSHOPS ARRANGED IN RESPONSE 4118 02:39:29,000 --> 02:39:31,200 TO THE NEEDS OF TECHNOLOGY 4119 02:39:31,200 --> 02:39:32,080 DEVELOPMENT PROJECT. 4120 02:39:32,080 --> 02:39:34,960 EVERY COMPONENT IS DESIGNED TO 4121 02:39:34,960 --> 02:39:38,480 INTERACT WITH NIBIB PROGRAM 4122 02:39:38,480 --> 02:39:38,960 STAFF. 4123 02:39:38,960 --> 02:39:41,920 NEXT SLIDE PLEASE. 4124 02:39:41,920 --> 02:39:42,240 PERFECT. 4125 02:39:42,240 --> 02:39:44,240 ANOTHER IMPORTANT ASPECT IS 4126 02:39:44,240 --> 02:39:44,960 ENABLING OF PARTNERSHIPS, AND 4127 02:39:44,960 --> 02:39:46,960 THIS IS SOMETHING WE HOPE TO 4128 02:39:46,960 --> 02:39:49,200 LEVERAGE IN MULTIPLE WAYS TO FIT 4129 02:39:49,200 --> 02:39:56,280 NEEDS OF FELLOW INSTITUTES. 4130 02:39:56,280 --> 02:39:57,520 BIOMATERIALS RELATED WORK EXISTS 4131 02:39:57,520 --> 02:39:58,680 AT MANY INSTITUTES BUT IN 4132 02:39:58,680 --> 02:40:00,640 GENERAL CAN BE DIFFICULT TO 4133 02:40:00,640 --> 02:40:01,560 BRING NOVEL BIOMATERIALS TYPES 4134 02:40:01,560 --> 02:40:04,160 TO INSTITUTES THAT FOCUS ON 4135 02:40:04,160 --> 02:40:06,080 CLINICAL CONCERNS, WE HOPE TO 4136 02:40:06,080 --> 02:40:08,480 LEVERAGE STRUCTURE TO BUILD 4137 02:40:08,480 --> 02:40:10,200 STRONGER BRIDGES BETWEEN THE 4138 02:40:10,200 --> 02:40:12,480 NOVEL BIOMATERIALS PLATFORMS WE 4139 02:40:12,480 --> 02:40:14,960 DEVELOP AND CLINICAL FOCI OF 4140 02:40:14,960 --> 02:40:17,720 DISEASE SPECIFIC INSTITUTES FOR 4141 02:40:17,720 --> 02:40:20,080 A PATHWAY INTO PROGRAMS THAT 4142 02:40:20,080 --> 02:40:21,880 EXIST AT PARTNER INSTITUTES. 4143 02:40:21,880 --> 02:40:24,880 WE CAN ACCOMMODATE EARLY STAGE 4144 02:40:24,880 --> 02:40:26,080 PARTNERSHIPS THROUGH MECHANISMS 4145 02:40:26,080 --> 02:40:29,120 FOR EXPLORATION OF NOVEL TARGETS 4146 02:40:29,120 --> 02:40:32,480 ADDRESSED THROUGH CREATION OF 4147 02:40:32,480 --> 02:40:32,720 PLATFORMS. 4148 02:40:32,720 --> 02:40:41,000 WE CAN ALSO LEVERAGE 4149 02:40:41,000 --> 02:40:41,480 TRANSLATIONAL BIPHASIC 4150 02:40:41,480 --> 02:40:43,120 MECHANISMS FOR THE PROTOTYPING 4151 02:40:43,120 --> 02:40:45,760 PHASE, PARTNERSHIPS CAN INCLUDE 4152 02:40:45,760 --> 02:40:46,680 LATE STAGE CHARACTERIZATION, 4153 02:40:46,680 --> 02:40:48,000 OPTIMIZATION TO NEEDS OF A 4154 02:40:48,000 --> 02:40:50,680 PARTICULAR DISEASE OR CLINICAL 4155 02:40:50,680 --> 02:40:50,960 INDICATION. 4156 02:40:50,960 --> 02:40:53,280 THIS GIVES ABILITY TO ADDRESS 4157 02:40:53,280 --> 02:40:57,080 VARIETY OF NEEDS INSTITUTES MAY 4158 02:40:57,080 --> 02:41:01,320 HAVE BUILDING STRONG CROSS-NIH 4159 02:41:01,320 --> 02:41:05,600 BRIDGES FOR BIOMATERIALS, 4160 02:41:05,600 --> 02:41:06,280 SHOWING FLEXIBILITY OF 4161 02:41:06,280 --> 02:41:07,080 INFRASTRUCTURE TO COVER THE 4162 02:41:07,080 --> 02:41:10,200 NEEDS OF THE FIELD OF 4163 02:41:10,200 --> 02:41:12,080 BIOMATERIALS BUT LEVERAGED FOR 4164 02:41:12,080 --> 02:41:12,840 OTHER PURPOSES AND APPLIED IN 4165 02:41:12,840 --> 02:41:15,240 THE FUTURE TO OTHER ENGINEERING 4166 02:41:15,240 --> 02:41:20,160 FIELDS WE SUPPORT AT NIBIB SUCH 4167 02:41:20,160 --> 02:41:23,560 AS SYNTHETIC BIOLOGY. 4168 02:41:23,560 --> 02:41:25,360 NEXT SLIDE PLEASE. 4169 02:41:25,360 --> 02:41:27,160 TO WRAP UP, WE'VE PRESENTED 4170 02:41:27,160 --> 02:41:28,120 BIOMATERIALS NETWORK CONCEPT 4171 02:41:28,120 --> 02:41:29,880 DESIGNED TO BUILD STRONGER 4172 02:41:29,880 --> 02:41:30,400 FOUNDATION UNDER EXCITING 4173 02:41:30,400 --> 02:41:32,640 BIOMATERIALS WORK OUR P.I.s 4174 02:41:32,640 --> 02:41:34,480 PROPOSE, USING NOVEL SUPPORT 4175 02:41:34,480 --> 02:41:37,240 FRAMEWORK BASED ON SUCCESSFUL 4176 02:41:37,240 --> 02:41:37,880 TECHNOLOGY DEVELOPMENT PROGRAMS, 4177 02:41:37,880 --> 02:41:41,400 CUSTOMIZED FOR NEEDS OF NIBIB 4178 02:41:41,400 --> 02:41:46,000 BIOMATERIALS P.I.s, WE HEAP 4179 02:41:46,000 --> 02:41:47,720 HOPE TO REREINFORCEMENT BRINGING 4180 02:41:47,720 --> 02:41:49,840 MORE NIBIB SOLUTIONS 4181 02:41:49,840 --> 02:41:52,320 SUCCESSFULLY FROM THE BENCH TO 4182 02:41:52,320 --> 02:41:53,480 BEDSIDE, AND WITH THAT WE THANK 4183 02:41:53,480 --> 02:41:55,720 YOU FOR YOUR TIME AND WE'LL TAKE 4184 02:41:55,720 --> 02:41:56,920 ANY QUESTIONS AND DISCUSSION YOU 4185 02:41:56,920 --> 02:42:04,320 MAY HAVE. 4186 02:42:04,320 --> 02:42:08,920 THANK YOU. 4187 02:42:08,920 --> 02:42:09,280 >> THANK YOU. 4188 02:42:09,280 --> 02:42:12,080 ANY COMMENTS OR QUESTIONS FROM 4189 02:42:12,080 --> 02:42:14,280 THE COUNCIL MEMBERS? 4190 02:42:14,280 --> 02:42:15,880 I SEE JOYCE. 4191 02:42:15,880 --> 02:42:24,280 >> YES, THANK YOU, STEPHANIE AND 4192 02:42:24,280 --> 02:42:24,800 LUISA. 4193 02:42:24,800 --> 02:42:25,760 MUCH NEEDED. 4194 02:42:25,760 --> 02:42:26,880 IT'S GREAT SEEING CONNECTION TO 4195 02:42:26,880 --> 02:42:29,600 THE OTHER INSTITUTES AT NIH. 4196 02:42:29,600 --> 02:42:30,200 WONDERING HOW MUCH INTERACTION 4197 02:42:30,200 --> 02:42:32,680 THERE ARE WITH OTHER FEDERAL 4198 02:42:32,680 --> 02:42:34,680 AGENCIES NAMELY LET'S SAY FDA 4199 02:42:34,680 --> 02:42:37,600 THINKING ABOUT LIKE 510(K) TO 4200 02:42:37,600 --> 02:42:42,040 ACCELERATE IF YOU HAVE LIKE 4201 02:42:42,040 --> 02:42:45,000 EXISTING MATERIALS, FOR EXAMPLE, 4202 02:42:45,000 --> 02:42:49,080 I'M A GRADUATE OF THE I-CORPS 4203 02:42:49,080 --> 02:42:50,280 PROGRAM, A GREAT OPPORTUNITY FOR 4204 02:42:50,280 --> 02:42:53,040 INDUSTRY PARTNERSHIPS AND ALSO 4205 02:42:53,040 --> 02:42:54,080 YOU MENTIONED STANDARDS SO NIST, 4206 02:42:54,080 --> 02:42:55,760 THERE'S A LOT OF GREAT 4207 02:42:55,760 --> 02:42:57,040 OPPORTUNITIES, I'M CURIOUS IF 4208 02:42:57,040 --> 02:43:00,560 YOU'VE BEEN TALKING TO THEM AS 4209 02:43:00,560 --> 02:43:00,880 WELL. 4210 02:43:00,880 --> 02:43:02,960 >> I THINK IN GENERAL AT NIBIB 4211 02:43:02,960 --> 02:43:06,120 THERE ARE CONVERSATIONS WITH 4212 02:43:06,120 --> 02:43:08,080 PEOPLE AT NSF, LIKELY NIST, AND 4213 02:43:08,080 --> 02:43:09,280 THE FDA, AND I THINK THAT'S 4214 02:43:09,280 --> 02:43:12,560 SOMETHING THAT WE WOULD LOOK FOR 4215 02:43:12,560 --> 02:43:13,240 OPPORTUNITIES TO PARTNER THROUGH 4216 02:43:13,240 --> 02:43:16,720 THE CENTERS THAT ARE PROVIDING 4217 02:43:16,720 --> 02:43:17,560 RESOURCES AND COORDINATION, THAT 4218 02:43:17,560 --> 02:43:20,320 MOST CERTAINLY WOULD BE OF 4219 02:43:20,320 --> 02:43:21,480 INTEREST. 4220 02:43:21,480 --> 02:43:24,760 AND LUISA, YOU'VE BEEN HAVING 4221 02:43:24,760 --> 02:43:27,240 CONVERSATIONS WITH NSF. 4222 02:43:27,240 --> 02:43:28,080 >> YEAH, DEFINITELY. 4223 02:43:28,080 --> 02:43:28,360 I AGREE. 4224 02:43:28,360 --> 02:43:32,400 THAT'S ONE OF THE EXCITING 4225 02:43:32,400 --> 02:43:35,240 THINGS, ABILITY TO BUILD WITH 4226 02:43:35,240 --> 02:43:36,680 EXISTING RESOURCES TO MAKE SURE 4227 02:43:36,680 --> 02:43:37,480 PEOPLE ARE TAKING ADVANTAGE, 4228 02:43:37,480 --> 02:43:38,720 SOMETHING THE CENTERS WILL HAVE 4229 02:43:38,720 --> 02:43:39,600 THE ABILITY TO DO SO THEY WILL 4230 02:43:39,600 --> 02:43:43,440 BE ON THE GROUND WITH TECHNOLOGY 4231 02:43:43,440 --> 02:43:43,960 DEVELOPMENT PROJECT. 4232 02:43:43,960 --> 02:43:46,640 WE ARE OF COURSE HAVING 4233 02:43:46,640 --> 02:43:47,680 DISCUSSIONS WITH OTHER AGENCIES 4234 02:43:47,680 --> 02:43:48,120 AS WELL. 4235 02:43:48,120 --> 02:43:50,080 I THINK AT THE NSF WE'RE TALKING 4236 02:43:50,080 --> 02:43:53,080 ABOUT THINGS FROM A BASIC 4237 02:43:53,080 --> 02:43:53,920 BIOMATERIALS PERSPECTIVE WHICH 4238 02:43:53,920 --> 02:43:55,040 WE'RE EXCITED ABOUT BUT OF 4239 02:43:55,040 --> 02:43:56,480 COURSE THERE ARE OTHER 4240 02:43:56,480 --> 02:44:02,080 CONVERSATIONS GOING ON AS WELL. 4241 02:44:02,080 --> 02:44:03,080 THANK YOU. 4242 02:44:03,080 --> 02:44:06,040 >> THANK YOU. 4243 02:44:06,040 --> 02:44:07,520 GILDA AND TEJAL. 4244 02:44:07,520 --> 02:44:09,520 >> THANK YOU. 4245 02:44:09,520 --> 02:44:10,560 MY COMPLIMENTS TO WHAT YOU'VE 4246 02:44:10,560 --> 02:44:12,080 DONE SO FAR. 4247 02:44:12,080 --> 02:44:14,160 NOT TO DIMINISH EXCITEMENT BUT 4248 02:44:14,160 --> 02:44:16,000 WHAT I FIND IS WHEN YOU TRY TO 4249 02:44:16,000 --> 02:44:17,720 GET NETWORKS TOGETHER AND GET 4250 02:44:17,720 --> 02:44:20,120 PEOPLE WRAPPED UP, THEY GET ALL 4251 02:44:20,120 --> 02:44:22,200 EXCITED BUT THEN SOMETIMES THEY 4252 02:44:22,200 --> 02:44:22,480 PETER OUT. 4253 02:44:22,480 --> 02:44:24,520 I'M JUST WONDERING IF THERE'S 4254 02:44:24,520 --> 02:44:27,480 BEEN SOME CONVERSATION AT THIS 4255 02:44:27,480 --> 02:44:28,880 POINT ABOUT SUSTAINING THE 4256 02:44:28,880 --> 02:44:31,160 INTEREST AND ENERGY AND 4257 02:44:31,160 --> 02:44:33,560 EXCITEMENT, HOW DO YOU SUSTAIN 4258 02:44:33,560 --> 02:44:34,880 THIS TYPE OF ACTIVITY? 4259 02:44:34,880 --> 02:44:38,920 NOT JUST SCALING IT BUT HOW DO 4260 02:44:38,920 --> 02:44:40,600 YOU SUSTAIN IT? 4261 02:44:40,600 --> 02:44:44,440 >> OH, THAT'S THE THING ABOUT 4262 02:44:44,440 --> 02:44:45,640 DEVELOPING CENTERS COORDINATING 4263 02:44:45,640 --> 02:44:46,400 AND PROVIDING RESOURCES, THEY 4264 02:44:46,400 --> 02:44:49,480 HAVE TO HAVE REGULAR 4265 02:44:49,480 --> 02:44:50,720 INTERACTIONS WITH THE GRANTEES. 4266 02:44:50,720 --> 02:44:53,720 SO, YOU CAN HAVE AN ANNUAL 4267 02:44:53,720 --> 02:44:56,960 MEETING BUT THERE'S THE 4268 02:44:56,960 --> 02:44:57,840 ASSESSMENT PORTION, ASSESSING 4269 02:44:57,840 --> 02:44:58,600 TECHNOLOGIES, PROBABLY ONCE OR 4270 02:44:58,600 --> 02:45:02,560 TWICE DURING THE AWARD PERIOD, 4271 02:45:02,560 --> 02:45:05,160 MORE SO OPPORTUNITIES TO HAVE 4272 02:45:05,160 --> 02:45:07,040 THE GRANTEES COME TOGETHER, 4273 02:45:07,040 --> 02:45:09,520 INTERACT BY WORKSHOPS OR WORKING 4274 02:45:09,520 --> 02:45:12,160 GROUPS AS NEEDED. 4275 02:45:12,160 --> 02:45:15,400 I'VE SEEN THAT AS A WAY TO 4276 02:45:15,400 --> 02:45:17,280 SUSTAIN EXCITEMENT, IT WORKS 4277 02:45:17,280 --> 02:45:17,920 WELL WITH OPPORTUNITY TO 4278 02:45:17,920 --> 02:45:19,400 INTERACT BEYOND AN ANNUAL 4279 02:45:19,400 --> 02:45:21,360 MEETING, SOMETHING YOU CAN DO 4280 02:45:21,360 --> 02:45:22,560 WITH THE CENTER APPROACHES, 4281 02:45:22,560 --> 02:45:25,360 BUILDING THAT IN, TRYING TO HAVE 4282 02:45:25,360 --> 02:45:26,080 MORE INTERACTION, MAINTAINING 4283 02:45:26,080 --> 02:45:26,880 THE DISCUSSION AROUND THE 4284 02:45:26,880 --> 02:45:30,160 TECHNOLOGIES AND WHERE THEY ARE 4285 02:45:30,160 --> 02:45:31,600 IN TERMS OF THEIR PROGRESS. 4286 02:45:31,600 --> 02:45:34,920 >> SOUNDS GOOD. 4287 02:45:34,920 --> 02:45:41,080 GOOD LUCK. 4288 02:45:41,080 --> 02:45:42,120 >> THANK YOU. 4289 02:45:42,120 --> 02:45:42,440 >> TEJAL? 4290 02:45:42,440 --> 02:45:47,480 >> WE CAN'T HEAR YOU. 4291 02:45:47,480 --> 02:45:49,040 >> YOU'RE MUTED, TEJAL. 4292 02:45:49,040 --> 02:45:51,640 >> CAN YOU HEAR ME NOW? 4293 02:45:51,640 --> 02:45:52,280 >> YES. 4294 02:45:52,280 --> 02:45:55,040 PERHAPS I SHOULD HAVE SAID 4295 02:45:55,040 --> 02:45:56,400 JASON, MAYBE THAT WOULD HAVE 4296 02:45:56,400 --> 02:45:57,400 CAUGHT YOUR ATTENTION. 4297 02:45:57,400 --> 02:45:59,560 >> THANK YOU FOR DOING THIS. 4298 02:45:59,560 --> 02:46:01,760 I THINK AGAIN AS SOMEBODY WHO 4299 02:46:01,760 --> 02:46:04,680 WORKS IN THE BIOMATERIALS FIELD 4300 02:46:04,680 --> 02:46:06,040 THIS IS MUCH NEEDED AND REALLY 4301 02:46:06,040 --> 02:46:08,200 THERE HAVE BEEN A NUMBER OF 4302 02:46:08,200 --> 02:46:11,080 CHALLENGES IN TERMS OF REALLY 4303 02:46:11,080 --> 02:46:12,680 ACCELERATING THE PACE OF 4304 02:46:12,680 --> 02:46:12,960 TECHNOLOGY. 4305 02:46:12,960 --> 02:46:17,080 ONE OF MY QUESTIONS, YOU SORT OF 4306 02:46:17,080 --> 02:46:20,440 TOUCHED ON THIS BRIEFLY, IS 4307 02:46:20,440 --> 02:46:23,080 PARTNERSHIPS WITH PHARMA AND THE 4308 02:46:23,080 --> 02:46:24,080 MEDICAL DEVICE INDUSTRY. 4309 02:46:24,080 --> 02:46:27,880 BECAUSE I THINK ONE OF MAYBE THE 4310 02:46:27,880 --> 02:46:29,360 DIFFERENCES BETWEEN THIS FIELD 4311 02:46:29,360 --> 02:46:31,280 IN PARTICULAR VERSUS MAYBE POINT 4312 02:46:31,280 --> 02:46:34,920 OF CARE DIAGNOSTICS OR OTHER 4313 02:46:34,920 --> 02:46:37,280 TYPES OF HARD TECHNOLOGIES IS 4314 02:46:37,280 --> 02:46:42,400 THAT SO MUCH OF WHAT DRIVES 4315 02:46:42,400 --> 02:46:43,480 APPLICATION AND DEVELOPMENT 4316 02:46:43,480 --> 02:46:45,240 REALLY IS CENTERED AROUND SORT 4317 02:46:45,240 --> 02:46:47,880 OF DEVELOPMENT EITHER WITHIN THE 4318 02:46:47,880 --> 02:46:51,120 PHARMACEUTICAL SECTOR OR MEDICAL 4319 02:46:51,120 --> 02:46:51,800 DEVICE SECTOR. 4320 02:46:51,800 --> 02:46:54,200 SO IS THERE A WAY TO ENGAGE 4321 02:46:54,200 --> 02:46:57,280 THOSE STAKEHOLDERS EARLY ON SUCH 4322 02:46:57,280 --> 02:46:58,880 THAT THEY FEEL LIKE THEY ARE 4323 02:46:58,880 --> 02:47:00,680 BOTH VESTED IN THE OUTCOMES OF 4324 02:47:00,680 --> 02:47:03,000 THE PROGRAM BUT ALSO CAN HELP 4325 02:47:03,000 --> 02:47:10,680 SHAPE SOME OF THE FOCUS AREAS AS 4326 02:47:10,680 --> 02:47:10,880 WELL? 4327 02:47:10,880 --> 02:47:11,280 >> LIKELY SO. 4328 02:47:11,280 --> 02:47:14,000 ONE PART OF WHAT WE WANT IS 4329 02:47:14,000 --> 02:47:15,200 ACTUALLY TO FACILITATE 4330 02:47:15,200 --> 02:47:16,480 PARTNERSHIPS AND INTERACTIONS 4331 02:47:16,480 --> 02:47:18,280 WITH CONSULTANTS, HOW TO HAVE A 4332 02:47:18,280 --> 02:47:20,720 CHANCE TO SEE SOME TECHNOLOGIES 4333 02:47:20,720 --> 02:47:21,880 AT SOME EARLIER STAGES. 4334 02:47:21,880 --> 02:47:26,120 DOING SOME SORT OF MARKET 4335 02:47:26,120 --> 02:47:27,760 ANALYSIS AND ALSO THINKING ABOUT 4336 02:47:27,760 --> 02:47:29,080 REGULATORY CONSIDERATIONS EARLY 4337 02:47:29,080 --> 02:47:30,960 ON TO START THINKING ABOUT WHAT 4338 02:47:30,960 --> 02:47:32,600 IS OF INTEREST WHEN YOU GET 4339 02:47:32,600 --> 02:47:33,680 FURTHER ALONG TO THE CLINICAL 4340 02:47:33,680 --> 02:47:35,880 STAGES SO YOU CAN THINK ABOUT 4341 02:47:35,880 --> 02:47:38,120 THAT IN THE EARLY TECHNOLOGY 4342 02:47:38,120 --> 02:47:42,560 DEVELOPMENT. 4343 02:47:42,560 --> 02:47:44,240 YEAH, SO IT'S SOMETHING THAT'S 4344 02:47:44,240 --> 02:47:44,880 SORELY NEEDED. 4345 02:47:44,880 --> 02:47:46,440 YOU DON'T WANT TO GET SO 4346 02:47:46,440 --> 02:47:49,480 ADVANCED YOU'RE AT A POINT WHERE 4347 02:47:49,480 --> 02:47:52,680 YOU'RE NOT NECESSARILY 4348 02:47:52,680 --> 02:47:53,280 DEVELOPING SOMETHING THAT'S 4349 02:47:53,280 --> 02:47:54,520 APPROPRIATE MOVING FORWARD AND I 4350 02:47:54,520 --> 02:47:57,960 THINK WE'VE SEEN THAT HAPPEN. 4351 02:47:57,960 --> 02:48:06,560 >> IT HAPPENS QUITE COMMONLY. 4352 02:48:06,560 --> 02:48:09,840 >> JOYCE AGAIN? 4353 02:48:09,840 --> 02:48:12,720 >> YES, TO FULL UP, ANOTHER 4354 02:48:12,720 --> 02:48:16,760 EARLY STAKEHOLDER IS THE PAYORS, 4355 02:48:16,760 --> 02:48:17,520 LIKE INSURANCE COMPANIES, A LOT 4356 02:48:17,520 --> 02:48:21,240 OF US HAVE BEEN THERE WHERE YOU 4357 02:48:21,240 --> 02:48:21,880 END UP MAKING SOMETHING WHERE 4358 02:48:21,880 --> 02:48:27,640 IT'S NOT GOING TO BE 4359 02:48:27,640 --> 02:48:28,400 REIMBURSED, THAT'S CRITICAL TO 4360 02:48:28,400 --> 02:48:30,000 HAVE THEM AS A KEY STAKEHOLDER 4361 02:48:30,000 --> 02:48:30,800 AS WELL. 4362 02:48:30,800 --> 02:48:32,680 >> THANK YOU FOR POINTING THAT 4363 02:48:32,680 --> 02:48:32,920 OUT. 4364 02:48:32,920 --> 02:48:42,160 THAT'S COME UP, FOR CERTAIN. 4365 02:48:42,160 --> 02:48:43,640 4366 02:48:43,640 --> 02:48:47,280 >> ANY OTHER COMMENTS? 4367 02:48:47,280 --> 02:48:50,360 >> I DIDN'T PUT MY HAND UP, 4368 02:48:50,360 --> 02:48:52,560 MAYBE I COULD JUMP IN. 4369 02:48:52,560 --> 02:48:54,720 THESE ARE EXCELLENT COMMENTS 4370 02:48:54,720 --> 02:48:58,080 THAT I THINK GO TO EXACTLY WHAT 4371 02:48:58,080 --> 02:48:59,960 WE'VE DONE WITH RADx UNDER THE 4372 02:48:59,960 --> 02:49:01,920 PRESSURE OF A PANDEMIC AND A 4373 02:49:01,920 --> 02:49:05,960 VERY FOCUSED PROBLEM TO SOLVE. 4374 02:49:05,960 --> 02:49:08,960 AND WE'RE MEETING -- JILL AND I 4375 02:49:08,960 --> 02:49:10,680 MEET WEEKLY WITH CMS. 4376 02:49:10,680 --> 02:49:12,880 WE MEET WITH FDA OF COURSE AND 4377 02:49:12,880 --> 02:49:14,080 CDC. 4378 02:49:14,080 --> 02:49:16,880 AND WE HAVE OUR ARGUMENTS, 4379 02:49:16,880 --> 02:49:18,560 ESPECIALLY WITH CDC. 4380 02:49:18,560 --> 02:49:20,880 BUT IN THE END WE'VE REALLY 4381 02:49:20,880 --> 02:49:24,480 HELPED CHANGE THEIR SET POINT 4382 02:49:24,480 --> 02:49:26,760 AND THEIR EXPECTATIONS. 4383 02:49:26,760 --> 02:49:28,920 WHEN WE STARTED THEY FELT LIKE 4384 02:49:28,920 --> 02:49:31,480 LABORATORY TESTS WERE THE GOLD 4385 02:49:31,480 --> 02:49:32,680 STANDARD, NOBODY SHOULD BE OR 4386 02:49:32,680 --> 02:49:34,520 NEEDED TO DO TESTS AT HOME. 4387 02:49:34,520 --> 02:49:40,200 THAT WAS THE CLASSIC 4388 02:49:40,200 --> 02:49:40,920 LABORATORYIAN PERSPECTIVE AND 4389 02:49:40,920 --> 02:49:46,000 NOW THEY ACKNOWLEDGE OVER OVER 4390 02:49:46,000 --> 02:49:48,720 THE COUNTER TESTS HAVE BEEN 4391 02:49:48,720 --> 02:49:49,640 TRANSFORMATIONAL MANAGING THE 4392 02:49:49,640 --> 02:49:51,120 PANDEMIC, WE'RE HOPING TO BRING 4393 02:49:51,120 --> 02:49:52,320 THESE INTO THE MATERIALS SIDE 4394 02:49:52,320 --> 02:49:53,800 BUT WE NEED USE CASES. 4395 02:49:53,800 --> 02:49:57,480 BECAUSE IT'S GOING TO BE THE USE 4396 02:49:57,480 --> 02:50:00,400 CASES THAT ALLOW US TO DRIVE 4397 02:50:00,400 --> 02:50:02,400 FORWARD THE CONSORTIA, BEGIN TO 4398 02:50:02,400 --> 02:50:03,080 DE-RISK SOME APPROACHES, AND 4399 02:50:03,080 --> 02:50:04,920 THAT WILL BE THE MODEL THAT WE 4400 02:50:04,920 --> 02:50:07,280 USE FOR THE NEXT ONE AND THE 4401 02:50:07,280 --> 02:50:09,880 NEXT ONE. 4402 02:50:09,880 --> 02:50:17,640 SO, I OFTEN THINK OF SAM, MY 4403 02:50:17,640 --> 02:50:19,600 COLLEAGUE SAM, AND FDG-PET AND 4404 02:50:19,600 --> 02:50:22,480 SIMON BECAUSE THE WAY THAT THAT 4405 02:50:22,480 --> 02:50:24,200 COMMUNITY, YOU KNOW, RALLIED 4406 02:50:24,200 --> 02:50:27,920 AROUND FDG AS A CONTRAST AGENT 4407 02:50:27,920 --> 02:50:29,240 PUSHED THAT PARTICULAR IMAGING 4408 02:50:29,240 --> 02:50:30,760 TECHNOLOGY THROUGH AND ACROSS 4409 02:50:30,760 --> 02:50:34,240 THE FINISH LINE AND CMS 4410 02:50:34,240 --> 02:50:34,560 REIMBURSEMENT. 4411 02:50:34,560 --> 02:50:37,400 WE'VE SEEN SOME OF THAT KIND OF 4412 02:50:37,400 --> 02:50:40,880 RALLYING AROUND IN IN VITRO 4413 02:50:40,880 --> 02:50:41,600 DIAGNOSTICS UNDER THIS 4414 02:50:41,600 --> 02:50:43,680 PARTICULAR TIME WHERE THEY WERE 4415 02:50:43,680 --> 02:50:46,640 REVOLUTIONARY TECHNOLOGY, SO TO 4416 02:50:46,640 --> 02:50:48,160 SPEAK, THAT HAD NOT BEEN FULLY 4417 02:50:48,160 --> 02:50:50,280 DEPLOYED AND WE HAVE NOW MOVED 4418 02:50:50,280 --> 02:50:52,680 THEM INTO THE HOME AT A TOTALLY 4419 02:50:52,680 --> 02:50:53,200 DIFFERENT SCALE. 4420 02:50:53,200 --> 02:50:55,480 SO, THIS IS GOING TO REALLY 4421 02:50:55,480 --> 02:50:56,760 DEPEND ON YOU, LEADERS AND 4422 02:50:56,760 --> 02:50:59,160 EXPERTS IN THE FIELD, TO HELP 4423 02:50:59,160 --> 02:51:02,520 IDENTIFY KEY USE CASES WHERE 4424 02:51:02,520 --> 02:51:05,080 IT'S A COMBINATION OF DOABILITY 4425 02:51:05,080 --> 02:51:06,920 IMPORTANCE AND NOT TOO HARD. 4426 02:51:06,920 --> 02:51:10,200 SO THAT'S WHAT WE'RE LOOKING 4427 02:51:10,200 --> 02:51:16,520 FOR. 4428 02:51:16,520 --> 02:51:20,280 >> ANOTHER QUICK POINT TO TIE TO 4429 02:51:20,280 --> 02:51:21,760 THE PREVIOUS PRESENTATION ABOUT 4430 02:51:21,760 --> 02:51:22,680 DATA AND DATABASES. 4431 02:51:22,680 --> 02:51:25,480 I THINK IT'S GOING TO BE 4432 02:51:25,480 --> 02:51:28,320 CRITICAL TO HAVE KIND OF A 4433 02:51:28,320 --> 02:51:29,280 BIOMATERIALS DATABASE. 4434 02:51:29,280 --> 02:51:31,480 THERE'S BEEN EFFORTS IN THE PAST 4435 02:51:31,480 --> 02:51:33,560 AND NIST HAS DONE REALLY 4436 02:51:33,560 --> 02:51:34,920 WONDERFUL THINGS BUT IT'S REALLY 4437 02:51:34,920 --> 02:51:35,960 A CHALLENGE. 4438 02:51:35,960 --> 02:51:40,160 JUST EVEN TO GET STANDARDS. 4439 02:51:40,160 --> 02:51:42,560 IT'S WONDERFUL THE MODEL YOU 4440 02:51:42,560 --> 02:51:43,960 HAVE COORDINATING CENTERS AND 4441 02:51:43,960 --> 02:51:45,480 NETWORKS TOGETHER SO I THINK 4442 02:51:45,480 --> 02:51:47,600 THAT'S A GOOD MODEL BUT WE 4443 02:51:47,600 --> 02:51:49,480 DEFINITELY HAVE TO THINK HOW TO 4444 02:51:49,480 --> 02:51:51,400 HANDLE THE DATA AND MAKE THAT 4445 02:51:51,400 --> 02:51:56,880 KIND OF STANDARDIZED SO YOU CAN 4446 02:51:56,880 --> 02:51:57,360 COMPARE. 4447 02:51:57,360 --> 02:51:59,120 >> THANK YOU FOR THAT COMMENT. 4448 02:51:59,120 --> 02:52:02,480 I DEFINITELY AGREE. 4449 02:52:02,480 --> 02:52:03,040 BIOMATERIAL STANDARDS IS 4450 02:52:03,040 --> 02:52:05,880 SOMETHING THAT BEING BUILT IN AN 4451 02:52:05,880 --> 02:52:07,440 INDUSTRY, ACADEMIA ISN'T 4452 02:52:07,440 --> 02:52:08,520 NECESSARILY PICKING THEM UP AND 4453 02:52:08,520 --> 02:52:09,840 WE TRIED TO BUILD THAT INTO 4454 02:52:09,840 --> 02:52:11,680 THIS, BEING ABLE TO GET THE DATA 4455 02:52:11,680 --> 02:52:18,920 OUT THAT WE CAN LEVERAGE AS WELL 4456 02:52:18,920 --> 02:52:22,520 . 4457 02:52:22,520 --> 02:52:24,000 >> OKAY. 4458 02:52:24,000 --> 02:52:26,280 HEARING NO MORE COMMENTS, THANK 4459 02:52:26,280 --> 02:52:28,280 YOU FOR YOUR SUPPORT OF 4460 02:52:28,280 --> 02:52:31,080 ASSESSMENT AS WELL AS EXCELLENT 4461 02:52:31,080 --> 02:52:32,040 THINGS TO FACTOR IN. 4462 02:52:32,040 --> 02:52:34,560 WE NEED TO MAKE SURE EVERYONE 4463 02:52:34,560 --> 02:52:36,560 WHO IS INVOLVED IS INVOLVED, 4464 02:52:36,560 --> 02:52:37,840 EVERYONE WHO NEEDS TO BE 4465 02:52:37,840 --> 02:52:38,640 INVOLVED IS INVOLVED. 4466 02:52:38,640 --> 02:52:41,480 SO THANK YOU VERY MUCH. 4467 02:52:41,480 --> 02:52:43,840 THAT'S OUR LAST PRESENTATION. 4468 02:52:43,840 --> 02:52:46,960 SO, BRUCE, BEFORE WE ADJOURN IF 4469 02:52:46,960 --> 02:52:48,160 YOU WANTED TO MAKE ANY FINAL 4470 02:52:48,160 --> 02:52:51,040 REMARKS AT THE END OF OPEN 4471 02:52:51,040 --> 02:52:51,920 SESSION? 4472 02:52:51,920 --> 02:52:52,200 >> SURE. 4473 02:52:52,200 --> 02:52:52,880 THANKS, DAVE. 4474 02:52:52,880 --> 02:52:56,680 I WANT TO THANK COUNCIL AGAIN 4475 02:52:56,680 --> 02:52:59,000 FOR YOUR ENGAGEMENT, 4476 02:52:59,000 --> 02:52:59,760 PARTICIPATION, INCREDIBLE 4477 02:52:59,760 --> 02:53:02,280 FEEDBACK, DYNAMIC CONVERSATION, 4478 02:53:02,280 --> 02:53:04,360 WE'RE LOOKING FORWARD TO MAY 4479 02:53:04,360 --> 02:53:10,800 WHEN WE HAVE AN IN-PERSON 4480 02:53:10,800 --> 02:53:12,240 MEETING, WE HOPE, HOPEFULLY 4481 02:53:12,240 --> 02:53:17,240 MOVING INTO THAT DOMAIN IN 4482 02:53:17,240 --> 02:53:19,000 REGULAR INTERACTIONS. 4483 02:53:19,000 --> 02:53:21,200 AND I THINK THE ENTIRE NIBIB 4484 02:53:21,200 --> 02:53:22,680 STAFF, WE'RE LIKE A START-UP 4485 02:53:22,680 --> 02:53:28,360 WHEN YOU COMPARE US TO THE MORE 4486 02:53:28,360 --> 02:53:30,360 CORPORATE INSTITUTES LIKE NIAID 4487 02:53:30,360 --> 02:53:32,360 AND NCI AND OPERATE LIKE THAT, 4488 02:53:32,360 --> 02:53:33,960 EVERYBODY IS ENGAGED, 4489 02:53:33,960 --> 02:53:35,920 CONSIDERING TO THIS COUNCIL 4490 02:53:35,920 --> 02:53:37,280 MEETINGS, LIKE A SMALL BOARD OF 4491 02:53:37,280 --> 02:53:39,720 DIRECTORS MEETING FOR A START-UP 4492 02:53:39,720 --> 02:53:39,960 COMPANY. 4493 02:53:39,960 --> 02:53:40,960 SO WE APPRECIATE EVERYBODY'S 4494 02:53:40,960 --> 02:53:43,160 WORK ON BEHALF OF THAT AND ALL 4495 02:53:43,160 --> 02:53:44,920 OF YOUR ATTENTION AND FEEDBACK. 4496 02:53:44,920 --> 02:53:46,920 EVERYONE IS LISTENING TO WHAT 4497 02:53:46,920 --> 02:53:47,960 YOU SAY. 4498 02:53:47,960 --> 02:53:49,080 AND WE'LL BE INTEGRATING THAT 4499 02:53:49,080 --> 02:53:50,880 INTO WHAT HOPEFULLY WILL BE 4500 02:53:50,880 --> 02:53:52,120 ANOTHER EXCITING PRESENTATION IN 4501 02:53:52,120 --> 02:53:57,200 THE NEXT COUNCIL. 4502 02:53:57,200 --> 02:53:58,960 THANK YOU ALL. 4503 02:53:58,960 --> 02:54:00,720 >> THANK YOU, BRUCE, FROM ME AND 4504 02:54:00,720 --> 02:54:01,480 JILL AND OTHER COLLEAGUES, THANK 4505 02:54:01,480 --> 02:54:02,680 YOU VERY MUCH. 4506 02:54:02,680 --> 02:54:03,880 BEFORE I ADJOURN OPEN SESSION, 4507 02:54:03,880 --> 02:54:08,960 I'D LIKE TO REMIND COUNCIL 4508 02:54:08,960 --> 02:54:09,600 MEMBERS AND NIBIB STAFF CLOSED 4509 02:54:09,600 --> 02:54:13,480 SESSION WILL BE IN A SEPARATE 4510 02:54:13,480 --> 02:54:14,480 ZOOM LINK. 4511 02:54:14,480 --> 02:54:15,800 LET'S TAKE A FIVE-MINUTE BREAK. 4512 02:54:15,800 --> 02:54:20,600 YOU SAW FROM THE ELECTRONIC 4513 02:54:20,600 --> 02:54:21,680 COUNCIL BOOK, IT'S A BRIEF 4514 02:54:21,680 --> 02:54:23,520 CLOSED SESSION, WE CAN READILY 4515 02:54:23,520 --> 02:54:25,640 BE DONE ON TIME. 4516 02:54:25,640 --> 02:54:27,000 NO WORRIES. 4517 02:54:27,000 --> 02:54:30,600 SO WE'LL START AT LIKE, SAY, 4518 02:54:30,600 --> 02:54:32,600 3:05, IF EVERYONE IS OKAY WITH 4519 02:54:32,600 --> 02:54:33,080 THAT. 4520 02:54:33,080 --> 02:54:34,800 I'D LIKE TO THANK OUR VISITORS 4521 02:54:34,800 --> 02:54:36,280 FOR ATTENDING ON VIDEOCAST. 4522 02:54:36,280 --> 02:54:39,640 WE HOPE YOU CAN ATTEND THE NEXT 4523 02:54:39,640 --> 02:54:42,200 COUNCIL MEETING, IN VIDEO. 4524 02:54:42,200 --> 02:54:44,800 HOPEFULLY IN PERSON IN THE MAY 4525 02:54:44,800 --> 02:54:46,240 OF 2023 MEETING. 4526 02:54:46,240 --> 02:54:48,200 SO THIS OPEN SESSION OF THE 4527 02:54:48,200 --> 02:54:52,120 60th MEETING OF THE NIBIB 4528 02:54:52,120 --> 02:54:53,560 NATIONAL ADVISORY COUNCIL IS 4529 02:54:53,560 --> 00:00:00,000 HEREBY ADJOURNED.