GOOD MORNING, THANK YOU.
WELCOME TO THE 66th MEETING OF
THE NATIONAL ADVISORY COUNCIL
FOR BIOMEDICAL IMAGING AND
BIOENGINEERING.
I AM DAVID GEORGE EXECUTIVE
SECOND QUARTER OF THE COMMITTEE.
OUR DEPUTY IS FINALIZING HER
DIRECTIONS TO THE MEETING.
SHE IS IN FACT HERE.
I'LL BE MENTIONING THAT IN A
MINUTE, JILL.
SO THIS COUNCIL MEETING IS.
TO THE PUBLIC EXCEPT FOR THE
REVIEW OF PENDING GRANT
APPLICATIONS THE OPEN SESSION IS
BEING RECORDED FOR NIH ARCHIVES.
WE ASK COUNCIL MEMBERS AT THE
THE TABLE TO PLEASE USE YOUR
MICROPHONE WHEN SPEAKING, THANK
YOU.
FOR EVERYONE IN THE ROOM, JILL
AND DAVID TOO, PLEASE MUTE YOUR
PHONES.
TURN OFF ANY SOUND YOU MAY HAVE
ON YOUR COMPUTERS.
THANK YOU.
WE WELCOME ALL OF OUR COUNCIL
MEMBERS AND EX-OFFICIOS AND
SPECIAL GUEST.
MEMBERS OF THE PUBLIC WHO WISH
TO EXPRESS VIEWS FOR ITEMS
DISCUSSED DURING THE MEETING MAY
DO SO BY WRITING ME AT
INFO@NIBIB.gov.
PLEASE PUT NIBIB COUNCIL IN THE
SUBJECT LINE OF THE E-MAIL.
SOME BIG ANNOUNCEMENTS, I'D LIKE
TO NOTE FOR THE RECORD WE HAVE A
QUORUM FOR TODAY'S MEETING.
I'D LIKE TO THANK THE NIBIB
MANAGEMENT OFFICER PAM GLICKMAN
AND ALICE HOPKINS AND THEY CAN
HELP YOU WITH TRAVEL AND
ANYTHING ELSE YOU MAY NEED AND
WOULD LIKE TO RECOGNIZE DAVID
DAVA AT THE PODIUM THERE AND MY
COLLEAGUES AT NIBIB AND NIHIT
AND THE VIDEOCAST AND THE
ARRANGEMENTS FOR TODAY'S
MEETING.
I ALSO NEED TO POINT OUT THE
PROCEEDINGS ARE GOVERNED BY THE
FEDERAL ADVISORY COMMITTEE KNOWN
AS FACA.
IN ADDITION TO THE GOVERNMENT
AND SUNSHINE ACT IT MEANS THIS
MEETING IS ANNOUNCED TO THE
PUBLIC IN THE FEDERAL REGISTER
AND IT CONSISTS OF AN OPEN
PORTION WE'RE IN THIS MORNING
AND THEN CLOSED SESSION FOR
DISCUSSION OF INDIVIDUAL
APPLICATIONS.
WE ANTICIPATE ADJOURNING OPEN
SESSION ABOUT 12:30.
IN TERMS OF FUTURE COUNCIL DATES
I'D LIKE TO MAKE A MOMENT TO
DRAW YOUR ATTENTION TO THE
FUTURE DATES LISTED ATHET BOTTOM
OF THE AGENDA AND FOR COUNCIL
MEMBERS WERE ALSO IN THE ECB AND
CURRENT COUNCIL TAB WHERE THE
AGENDA WAS POSTS.
REVIEW THE DATES OUR NEXT
MEETING IS FEBRUARY 22, 2025 A
VIDEO CONFERENCE MEETING.
WE'RE TAKING THE CADENCE OF THE
WEATHER.
LOOKING FURTHER IN THE FUTURE,
PLEASE NOTE WE RESCHEDULED THE
MAY 2025 MEETING TO THE MAY 25
SO IT DOESN'T CONFLICT WITH THE
ANNUAL ISMRN AND NEXT YEAR
MEETINGS WILL BE IN PERSON.
I'D LIKE TO MOVE TO APPROVAL OF
THE MINUTES.
THE DRAFT MINUTES WERE MADE
AVAILABLE TO YOU A COUPLE WEEKS
AGO IN THE ECB.
ARE THERE COMMENTS OR
MODIFICATIONS YOU'D LIKE IT MAKE
TO THE MINUTES?
HEARING NONE I'LL ENTERTAIN A
MOTION TO APPROVE.
SECOND?
ALL IN FAVOR, AYE.
ALL OPPOSED NAY.
THANK YOU.
THAT PASSES.
THANK YOU.
WE UPDATED THE OPERATING
PROCEDURES AND MADE THEM
AVAILABLE TO YOU.
WE UPDATED THE APPEAL SECTION TO
BE CONSISTENT WITH NIH POLICY
AND CLARIFY THE TYPE OF
COMMUNICATIONS THAT ARE BROUGHT
BEFORE COUNCIL AND I MADE A FEW
OTHER MINOR EDITORIAL
CLARIFICATIONS IN THERE.
ARE THERE COMMENTS OR
MODIFICATIONS YOU'D LIKE TO MAKE
TO THE OPERATING PROCEDURES?
HEARING NONE I'LL ENTERTAIN A
MOTION TO APPROVE.
IS THERE A SECOND?
ALL IN FAVOR, AYE.
OPPOSED NAY.
THANK YOU.
THAT PASSES.
SO WITH THOSE ADMINISTRATIVE
PROCEEDINGS I'LL TURN IT OVER TO
OUR DIRECTOR, BRUCE TROMBERG.
ACROSS THE HALL IS WHERE THE
COFFEE IS AND WHEN WE BREAK FOR
LUNCH THE FOOD WILL BE DELIVERED
TO THE BREAKOUT ROOM FOR THOSE
WHO ORDERED BUT EATING IN THE
CAFETERIA ON THE OTHER SIDE OF
THE LOBBY.
THIS IS YOUR LAST CHANCE TO GET
COFFEE BEFORE MY PRESENTATION.
>> WE HAVE A LOT TO GO OVER
TODAY.
PRETTY EXCITING COUNCIL SLATE
INCLUDING SEVERAL NEW COUNCIL
MEMBERS A RECORD AT LEAST FOR
US.
ECHOING DAVE I'D LIKE TO THANK
OUR TEAM FOR AMAZING COUNCIL
ORGANIZATION AND VERY NICE BEING
HERE AND NOT HAVING TO WORRY
ABOUT NIH SECURITY.
I HOPE YOU APPRECIATE A LITTLE
BIT EXTRA SLEEP.
OUR TEAM, PAM, ALISHA AND SHA
AND BEFORE COUNCIL WE SCHEDULE
AN HOUR AND A HALF AND I USUALLY
MAKE IT GO THREE OR FOUR HOURS
AND SOME DAY WE'LL DO IT IN AND
OUT OR AN OUR AND A HALF
POSSIBLY.
OUR SENIOR LEADERSHIP YOU ALL
KNOW JILL, DAVE, ANN, RICHARD,
MANU AND CHRIS, I'VE INTRODUCED
THEM MANY TIMES BUT A NEW
PICTURE THERE.
ANNA TAYLOR WE'RE PLEASED TO
HAVE HER AS OUR NEW DIRECTOR AT
THE OFFICE OF RESEARCH
ADMINISTRATION.
SHE'S WATCHING DAVID MANAGE
COUNCIL.
ADVERTISING AND WE HAVE OUR
ANNUAL HECTOR LOPEZ LECTURE AND
IT'S BISI BELL AN OUTSTANDING
PIONEERING SCIENTIST IN
ACOUSTICS.
AND WE'RE EXCITED TO HAVE HER AS
OUR SPEAKER.
MOVING TO NEW COUNCIL MEMBERS.
WE'VE GOT SIX NEW COUNCIL
MEMBERS.
I DON'T KNOW IF WE'RE KEEPING
RECORDS BUT IS THIS THE MOST
WE'VE EVERY INTRODUCED AT ONCE?
>> ABSOLUTELY.
LET ME GO COMPARE.
I NEGLECTED TO MENTION WE'RE BE
BEING JOINED ON THE ZOOM.
THANK YOU.
>> FANTASTIC.
THANK YOU.
I WONDER WHICH VERSION OF MY
TALK BECAUSE I THOUGHT I HAD
THOUGHT THIS WOULD TAKE ME 30,
40 MINUTES TO GO THROUGH ALL
SIX.
WITH APOLOGIES TO ALL OF YOU,
THESE ARE FANTASTIC AND
INCREDIBLY WELL KNOWN FOLKS.
I'M JUST GOING TO GO THROUGH
SOME MINIMAL INTRODUCTIONS AND
WE'RE APPRECIATE OF YOUR SERVICE
IN JOINING OUR COUNCIL.
LET ME START WITH TAMARA BAYNHAM
BRINGS ORGANIZATION EXPERTISE TO
COUNCIL AND FOUNDER OF INGENUITY
DEVICE RESEARCH.
SHE HOLDS MORE THAN 40
U.S. PATENTS IN NEURAL
MODULATION THERAPIES AND A
MEMBER OF THE VANDERBILT CENTER
FOR INNOVATION AND PARTNERSHIP.
RAFAEL LEE FOCUSES ON BIO
MECHANICS AND IS A SURGEON AND
BIOMEDICAL ENGINEER.
RAPHAEL USED TO SIT NEXT TO EACH
OTHER IN THE FIRST ROUND OF
DUTY.
AND TYRONE PORTER CENTENNIAL
PROFESSOR AND DEPARTMENT CHAIR
OF BIOMEDICAL CHAIR AT UT AUSTIN
AND TRANSLATES CHEMICAL AND BIO
ENGINEERED VESICLES FOR
DIAGNOSTIC AND THERAPEUTIC
APPLICATIONS.
CHRISTINE SCHMIDT IS A
DISTINGUISHED PROFESSOR AT THE J
PRUITT ENDOWED CHAIR AND CHAIR
FOR THE UNIVERSITY OF FLORIDA,
J. CRAYTOP PRUITT AND PIONEER IN
TISSUE ENGINEERING AND WOUND
HEALING.
AND BILL LAM IS A RESEARCH CHAIR
IN THE DEPARTMENT OF PEDIATRICS
AND THE DEPARTMENT OF BIOMARKER
ENGINEERING AT EMORY UNIVERSITY
AND GEORGIA TECH.
THE ASSOCIATE DEAN OF INNOVATION
FOR EMORY SCHOOL OF MEDICINE AND
PART OF THE PEDIATRIC TECHNOLOGY
CENTER AND IF THAT'S NOT ENOUGH
HE ALSO SERVES AS THE INAUGURAL
VICE PROVOST ENTREPRENEURSHIP
FOR EMORY UNIVERSITY.
AND KURT LANGLOTZ IS THE SENIOR
SOCIETY VICE PROVOST FOR
RESEARCH AT STANFORD.
A FOUNDER AND PAST PRESIDENT OF
THE RADIOLOGY ALLIANCE FOR
HEALTH SERVICES AND SERVED AS
PRESIDENT OF THE SOCIETY OF
IMAGING, INFORMATICS AND
MEDICINE AND CURRENTLY PRESIDENT
OF THE RADIOLOGICAL SOCIETY OF
NORTH AMERICA.
AN AMAZING SLATE OF COUNCIL
MEMBERS.
WE'RE GRATEFUL FOR YOUR SERVICE
AND WOE LOOK FORWARD TO MORE
INTERACTIONS BOTH LIVE AND OF
COURSE ON ZOOM IN THE COMING
MONTHS.
SO AS I ALLUDED TO RIGHT AT THE
BEGINNING WE'RE SUPER DELIGHTED
TO ANNOUNCE ANNA'S JOINING AFTER
A SUCCESSFUL SEARCH WE CONDUCTED
IN ORDER TO REPLACE DAVID GEORGE
WHO'S BEEN OPERATING IN THE DUAL
ROLE AS THE EXTRAMURAL SCIENCE
DIRECTOR AND THE ROLE OF OFFICE
RESEARCH ADMINISTRATION.
SHE COMES TO US FROM NINDS THE
NEUROLOGY INSTITUTE AT NIH AND
MADE CONTRIBUTIONS TO ANALYTICS
OVER 17 YEARS.
HER LEADERSHIP POSITIONS WERE
ACTING DEPUTY DIRECTOR, NINDS
DIFFING -- DIVISION OF
EXTRAMURAL ACTIVITIES AND PART
OF A 50-MEMBER OFFICE SHE
ESTABLISHED.
SHE RECEIVED HER Ph.D. FROM LAKE
FOREST AND BACHELOR'S AND
MASTER'S DEGREES IN MOLECULAR
BIOLOGY FROM THE UNIVERSITY OF
CENTRAL FLORIDA AND THANK YOU
DAVID FOR YOUR SERVICE, THANK
YOU, ANNA FOR JOINING US AND
TAKING OVER THIS OFFICE.
AND THANK YOU RAY.
-- GREG.
OKAY.
THESE ARE REALLY INAUGURAL AND
PIONEERING FOR US AND I WANTED
TO POINT OUT BRAD BOWER.
HE'S APPOINTED AS OUR FIRST
CHIEF OF ARTIFICIAL INTELLIGENCE
AND DATA SCIENCE TECHNICALLY WE
CALL THIS THE CHIEF A.I. AND
DATA SCIENCE OFFICER.
THANK YOU.
THIS IS I BELIEVE THE ONLY
POSITION OF ITS KIND.
THE FIRST AT THE NIH.
THIS WILL CHANGE.
EVERYBODY'S TRYING TO BRING IN
CHIEF A.I. AND DATA SCIENCE
OFFICERS BUT I THINK AS TRUE TO
OUR COMMUNITY, WE'RE ON THE
CUTTING EDGE AND HELPED DEFINE
US.
AS YOU HEARD FROM THE
BACKGROUND, HE'S BEEN AT NIBIB
FOR TWO YEARS AS A DATA
TECHNOLOGY AND ADVANCEMENT
SCHOLAR.
SHE'S BEEN WORKING WITH THE TEAM
TO -- HE'S BEEN WORKING WITH THE
TEAM TO EXPAND HIS REACH BEYOND
COVID WITH NEW PARTNERSHIPS AND
BRINGS 16 YEARS EXPANDING
LEADERSHIP, MARKET ROLES AND HE
HAS EXTENSIVE HARDWARE
BACKGROUND AND EXPERTISE.
HE'S WORKED CONCUSSION
DIAGNOSTICS, POINT-OF-CARE
DIAGNOSTICS AND A.I. ENABLED
PREDICTORS OF THE AUTISM
SPECTRUM DISORDER.
HE DID HIS Ph.D. AT DUKE IN
BIOMEDICAL ENGINEERING AND HIS
BACHELOR'S UNDERGRADUATE
EXPERIENCE AT CASE WESTERN
WORKING WITH ANDREW ROLLINS AND
HAS EXTENSIVE EXPERIENCE IN
DEVICE AND UNDERSTANDING,
INTERPRETING AND BRINGING A.I.
TECHNIQUES TO ANALYZE AND
EXTRACT NEW INFORMATION CONTENT.
SO WE'RE SO PLEASED TO HAVE BRAD
AS THIS NEW OFFICER.
A COUPLE OF OTHER STAFF UPDATES.
SO JOHN KULWATNO IS JOINING AND
HE'S AN UNDERGRAD AND ALUM OF
THE UNIVERSITY OF FLORIDA AND
MAJORED IN MATERIAL SCIENCE AND
ENGINEERING.
PERHAPS HE TOOK ONE OF
DRDR
DRDR.
DRDR
DR. SCHMIDT'S CLASSES AND AN
AAAS TECHNICAL AND TECHNOLOGY
FELLOW SUPPORTING PROGRAMS.
EXCELLENT EXPERTISE.
MANY OF OUR COUNCIL MEMBERS AND
THEIR COLLEAGUES INTERACT WITH
OUR GRANTS MANAGEMENT.
SO CINDY SHI IS A NEW MEMBER OF
OUR GRANTS MANAGEMENT TEAM.
SHE HAS SIX YEARS OF EXPERIENCE
IN EXTRAMURAL RESEARCH PROGRAMS
AND SPONSORED PROJECTS FROM
JOHNS HOPKINS AND HER GRADUATE
AND UNDER GRADUATE DEGREES ARE
IN FINANCE AND ACCOUNTING.
LOTS OF EXPERTISE THERE.
GLAD TO HAVE HER.
ONE MORE KIND OF A SAD NOTE BUT
EXCITED FOR TAYLOR.
SO TAYLOR GILLILAND MANY HAVE
INTERACTED WITH IN VARIOUS BASTS
IS LEAVING NIBIB AND TAKEN A
POSITION IN THE OFFICE OF THE
DIRECTOR AT NIH.
HE'S BEEN WITH US SINCE 2021 AS
THE SENIOR ADVISER FOR
INNOVATION PROGRAMS WITHIN MY
OFFICE, THE OFFICE OF THE
DIRECTOR AND HE'S REALLY
ADVANCED OUR RAD X INNOVATION
EXPERIENCE EXPANDED FROM COVID
INITIALLY, WHICH HE WAS ON
DETAIL WORKING ON IN 2020.
IN FACT LED OUR OFFICE OF
COMMUNICATIONS AND INSPIRED THE
RADX NAME.
AN HOMAGE TO SOUTHERN CLINICAL
RESEARCH AND THE RAD LAB FOR
INNOVATION ITSELF AND EXPANDED
THE CONCEPTS TO INCLUDE
TECHNOLOGIES AND POINT-OF-CARE
AND RAD X ENDOMETRIAL CHALLENGE
AMONG OTHERS AND STRUCTURED THEM
WITH OUR TEAM.
HE'S GOT AN ENORMOUS OPPORTUNITY
AND LEADERSHIP POSITION IN THE
OFFICE OF THE DIRECTOR WE CALL
THING OFF DPCPSI, I CAN'T TELL
YOU WHAT IT STANDS FOR WITHOUT
MY NOTES BUT IT'S WELL FUNDED
WITHIN THE OFFICE OF THE
DIRECTOR.
AS ALL OF YOU KNOW, YOU HAVE TO
TRAIN FOLKS AND SEE THEM MOVE
INTO POSITIONS OF INFLUENCE IN
YOUR ORGANIZATION.
SO WE'RE HOPEFUL TAYLOR WILL
CONTINUE TO CARRY ON THAT SPIRIT
AND ALLOW US TO GET MORE MARKET
SHARE FROM SOME OF THOSE
INITIATIVES.
OKAY.
SO MOVING INTO AN AREA THAT
EVERYONE IS INTERESTED IN.
OF COURSE HAVE NO NEW NEWS HERE.
THIS IS GOING TO BE KIND OF NOT
VERY EXCITING.
SO YOU KNOW WE SEE A SENATE AND
HOUSE BILL THAT HAVE BEEN
PROPOSED AND YOU'RE ALL
LISTENING TO THE DISCUSSIONS IS
THERE GOING TO BE A SHUT DOWN
AND IS ANYONE GOING TO AGREE ON
THESE.
THEY'RE ALL FAIRLY CLOSE TO THE
WHITE HOUSE BUDGET.
NO SIGNIFICANT INCREASES OR
DECREASES THERE.
WITH THE EXCEPTION OF THE SECOND
ROW WHERE YOU SEE NIBIB IN
MILLIONS AND THE HOUSE BILL AS
NA, WELL, I GUESS ALL OF YOU
I NOW HAVE SEEN THE ORIGIN OF
THE N/A WITHIN THE HOUSE BILL
THERE'S A PROPOSAL TO
RESTRUCTURE THE 27 INSTITUTE
CENTERS AND OFFICES.
NIBIB WOULD FOLD INTO ANOTHER
ENTITY.
BUT THANKFULLY OUR COMMUNITY IS
QUITE AWARE OF THAT AND WE FEEL
THE SUPPORT AND THAT'S KIND OF
ABOUT ALL I CAN COMMENT ON.
SO THAT'S AN INTERESTING
CHALLENGE GOING FORWARD.
PROBABLY THE CHALLENGE OF COMING
TO A RESOLUTION AND CONSENSUS ON
A BUDGET AND NOT SHUTTING THE
GOVERNMENT DOWN IS THE PRIMARY
ONE WE ALL NEED TO BE CONCERNED
ABOUT.
IN THESE BUILDS IS WE ALWAYS
LOVE WHEN THEY MENTION US BUT
DON'T NECESSARY GIVE US MORE
MONEY BUT IT'S GOOD TO BE
MENTIONED AND THERE'S COMMITTEE
REPORT LANGUAGE THAT RECOGNIZES
THE SUCCESS OF OUR RADX PROGRAM
AND COMMENTS OUR EFFORTS.
MULTIPLE INSTITUTES ARE REFERRED
TO AS SPECIFICALLY HAVING
COLLABORATED WITH AND BENEFITTED
FROM OUR EFFORTS AND THIS IS A
STEP IN THE LONG PROCESS FOR
RECEIVING APPRECIATION AND
RECOGNITION THAT CAN LEAD TO
MORE APPROPRIATIONS FOR
TECHNOLOGY.
BUT IT'S CERTAINLY A LONG AND
COMPLICATED APPROACH.
YOU HOLD MORE KEYS THAN WE DO AS
THE COMMUNITY.
WE TRY TO ELEVATE AND MAKE SURE
PEOPLE ARE AWARE OF WHAT OUR
COMMUNITY'S DOING BUT THE BALL
IS SORT OF BACK IN THE COURTS OF
ALL OF YOU.
WE HAVE A PAY LINE FOR A PARENT
RO1 ANNOUNCEMENT IN OUR FLAT
BUDGET YEAR AND DISCUSSED THE
COST-CUTTING STRATEGIES THE 16%
THAT WE WANT TO BE SURE THAT
YOUNG INVESTIGATORS AND NEW
INVESTIGATORS ARE
DISPROPORTIONATELY AFFECTED
WHICH HAPPENS IN THE FLAT
BUDGETS OR BUDGET REDUCTION
YEARS.
WE WERE ABLE TO ADJUST TO
CONSERVE A BIG AIM TO AWARD AS
MANY IF NOT MORE GRANTS THOUGH
THE TOTAL DOLLARS ARE NEGOTIATED
AND DAVE AND JILL CAN GIVE YOU
MORE DETAILS IF YOU'RE
INTERESTED IN THOSE TYPES OF
BUDGET CUTS.
ON COUNCIL I LOVED TO HEAR ABOUT
FUNDING OPPORTUNITIES.
I EMPHASIZE THESE THINGS AND
HOPEFULLY YOU GUYS ARE TAKING
GOOD NOTES AND I DO SEE SOME ARE
IMPORTANT THINGS OUR COMMUNITY
HAS BEEN HOPING FOR.
WHEN I WAS EXTRAMURAL A FEW OF
THESE I WISHED THE NIH WOULD
IMPLEMENT.
IT'S PARTICULARLY EXCITING FOR
ME TO SEE THESE COMING.
SO THE FIRST RFI IS FOR YOU TO
COMMENT ON IS THE TOPIC THAT
ANECDOTALLY OUR COMMUNITY HAS
BEEN DISCUSSING QUITE A WHILE.
WE TALKED ABOUT COUNCIL BEFORE.
THESE ARE WHAT ARE WE GOING TO
DO ABOUT POSTDOC CRISIS?
DO WE NEED THEM?
HOW ARE WE GOING TO TRAIN
POSTDOCS?
THE ADVISORY COUNCIL TO THE
DIRECTOR AT THE NIH HAS BEEN
TRACKING THIS.
AND HAVE BEEN CHARGED WITH
MAKING RECOMMENDATIONS ABOUT
POSTDOCS.
IN GENERAL THERE'S A NUMBER OF
SPECIFIC RECOMMENDATIONS
INCLUDING INCREASED SALARIES AND
BENEFITS AND SO FORTH WE
WONDER -- WE KNOW OUR COMMUNITY
IS A LITTLE DIFFERENT.
WE HAVE A LIMITED SUPPLY OF
POSTDOCS AND WE HAVE DEMAND FROM
MULTIPLE SOURCES FOR POSTDOCS.
IT'S NOT ALWAYS A PATHWAY THAT
LEADS TO -- IT'S NOT THAT
POPULAR ALL THE TIME.
AND SO WE WANTED TO GET A
DISCUSSION GOING ABOUT HOW WE
HAVE UNIQUE NEEDS AND WHAT WE
CAN POTENTIALLY DO TO WORK WITH
YOU TO ADDRESS SOME OF THE
PROBLEMS AND CHALLENGES OF
POSTDOCTORAL TRAINING.
ONE OF THE MECHANISMS FOR
RESPONDING TO THESE IDEAS WILL
BE THROUGH THE RFI AND ZEYNEP
WILL EXPLORE THE TOPIC.
ANOTHER RFI AND TOPIC THAT
BRINGS TOGETHER OUR TWO FAVORITE
AREAS IS WHAT ARE THE PRECISION
MEDICINE CHALLENGES AND
OPPORTUNITIES WHEN WE COMBINE
A.I. WITH IMAGING.
THOSE WHO DO IMAGING AND
CERTAINLY IN THE CLINICAL
COMMUNITY YOU RECOGNIZE AND A
THIRD PARTY AND SOME APPROACH TO
HELP FACILITATE THE EXTRACTION
OF MORE QUANTITATIVE AND
FUNDAMENTAL INFORMING CONTENT
ABOUT HOW PATIENTS ARE DOING AND
THEN THE NEXT LEVEL OF CHALLENGE
OF COURSE IS HOW DO YOU
INTEGRATE THAT WITH CLINICAL
RECORDS AND OTHER PIECES OF DATA
SO YOU CAN MAKE THE DECISIONS
ABOUT HEALTH CARE AND RESEARCH.
TO A LARGE EXTENT IT'S ADVANCING
WHAT'S GOING ON IN OUR RESEARCH
COMMUNITIES AND BOUTIQUEY
LABORATORIES TO BENEFIT PATIENTS
IN A MORE SPECTACULAR WAY.
SO YOU HAVE AN OPPORTUNITY TO
COMMENT ON THAT.
THERE'S THIS RFI.
IT'S AN AREA THAT'S CAPTURED THE
ATTENTION NOT JUST OF US THOUGH
VERY WONKY IMAGING TECHNOLOGY
A.I. PEOPLE BUT THE ENTIRE NIH.
THIS IS QUITE AMAZING.
THIS IS SUPPORTED WE THE OFFICE
OF DATA SCIENCE STRATEGY, ODSS.
IT'S SIMPLY THAT.
IT ADDRESSES A PROBLEM WE ALL
KNOW THAT IS QUITE UNIQUE TO US.
I GUESS IT TOOK A WHILE FOR THE
REST OF NIH TO REALIZE IT'S A
HUGE ISSUE.
HOPEFULLY OUR COMMUNITY CAN
RESPOND TO THIS INITIATIVE.
AND THE COMPANION PIECE IS THE
PERSON.
SO PERHAPS LIKE MANY OF YOU WHAT
I USED TO DO AS AN INSTITUTE
DIRECTOR WAS HIRE A SOFTWARE
ENGINEER WHO COULD WORK FOR
EVERYONE AND DIVIDE THEIR TIME.
THE TIME SHARING DOESN'T WORK
OUT WELL.
IT WORKS OKAY.
IT'S BETTER THAN NOTHING.
HERE YOU HAVE A CHANCE TO REALLY
BRING IN SOFTWARE ENGINEERS AND
PROMOTE IT AS A CAREER TRACK SO
THE RECOGNITION OF THIS AND IT'S
IMPORTANCE IN ACADEMIA THE TIME
HAS COME.
HOPEFULLY THESE REALLY IMPORTANT
RFPs WILL REPEAT THEMSELVES AND
HAVE OPPORTUNITIES FOR THESE
ONGOING.
I HOPE OUR COMMUNITY REALLY
RESPONDS.
THE NEXT ONE I THOUGHT WHY DO I
HAVE TO GO TO NSF TO DO ONE
THING AND THEN NIH AND IT'S
COMPLICATED TO GO TO MULTIPLE
AGENCIES.
COULDN'T THEY COORDINATE AND WE
SUPPORT EARLIER STAGE INNOVATION
AND YOU MAY GET TO A POINT WHERE
YOU ACTUALLY BELIEVE THIS IS
GOING TO GO SOME PLACE.
YOU HAVE YOUR APPLICATION IN
MIND AND THEN IT'S ANOTHER YEAR
BEFORE YOU GET NIH SUPPORT.
THIS IS AN ABSOLUTELY BRILLIANT
LOTS OF HARD WORK FROM TUBA AND
MANY OF OUR PEOPLE WORKING
CLOSELY WITH NSF BENEFITING A
LOT FROM OUR SPECIAL
RELATIONSHIP WITH THE DIRECTOR
AT NSF AND THIS IS A SMOOTH
TRANSITION.
TALK TO TUBA.
SHE INFORMATIONS THE MECHANISM
OF THIS WELL BECAUSE SHE
CONSTRUCTED THIS BUT IT'S A
BIPHASIC AWARD WITH NO GAP.
THE APPLICATION FIELD IS
SOMEWHAT RESTRICTED WITH RESPECT
TO WHAT OUR COMMUNITY'S GOING
BUT WE'RE HOPING TO EXPAND THIS.
THERE'S SO MANY AREAS THAT WILL
BE INCREDIBLY IMPACTED WITH THIS
TWO-STEP BIPHASIC AWARD WITH A
SMOOTH CONTRIBUTION BETWEEN THE
TWO.
TAYLOR OUR RADX DIVERSIFIED
CHALLENGE LEAD CREATED A
STRUCTURE WITH THE ACT ENDO
CHALLENGE DESIGN TO SHORTEN THE
TIME TO ENDOMETRIOSIS DIAGNOSIS,
POSSIBLY ELIMINATE THE INVASIVE
TECHNIQUES AND IMPROVE
ACCESSIBILITY OF THE DIAGNOSTIC
APPROACHES.
EVERYBODY KNOWS SOMEONE WHO IS
AFFECTED BY THIS TO SOME DEGREE
AND AFFECTS WOMEN ACROSS THEIR
LIFE TIME.
AN YOU ARE -- URGENTLY NEEDED
AREA AND HOPE THERE'S IMAGING
MATERIALS AND CREATIVITY AND
ENGINEERED BIOLOGIC SYMPTOMS AND
LOTS OF OPPORTUNITY HERE.
IN MANY WAYS WE TALKED ABOUT
DR. CLAYTON THE KEYNOTE SPEAKER
AND I THINK THERE'S MOMENTUM AND
EXCITEMENT ABOUT HOW OUR
COMMUNITY IN PARTICULAR CAN
CONTRIBUTE.
SHE IS REAL EXCITED ABOUT ALL OF
THAT.
I HOPE MORE RESOURCES ARE
AVAILABLE.
IT'S AN ABOUT START.
IN CHARACTERISTIC FASHION FOR US
WE'RE IMPATIENT SO IT'S A FAST
MECHANISM.
IT'S NOT WHERE YOU WRITE A
PROPOSAL AND PERHAPS A YEAR
LATER YOU GET FUNDS.
SO THIS IS A CHALLENGE, $3
MILLION IN TOTAL AND PRICE
COMPETITION TYPE OF FORMAT.
YOU DON'T HAVE TO FINISH IT WHEN
YOU WRITE YOUR THING.
YOU CAN HAVE STAGE GATES AND
PROGRESS THROUGH THESE AWARDS.
THE LAST FUNDING I WANT TO
HIGHLIGHT WE'VE MENTIONED BEFORE
WITH A CONSTANT EXPLOSION OF
A.I. AND BIOONIC -- BIONIC
DEVICES IT'S NEVER BEEN MORE
IMPORTANT.
AND MARIAH?
THERE ARE MANY ETHICAL ISSUES
WITH START-UPS THAT MAY MAKE
SOMETHING THERAPEUTIC TODAY AND
SO THESE ARE IMPORTANT
CHALLENGES TO OUR COMMUNITY TO
GET INVOLVED WITH AND BEGIN TO
ADDRESS.
THANKS MARIAH.
YOU CAN PUT THE FACE TOGETHER
AND THIS IS AN EXCITING CHANCE.
ALL OF YOU THINK QUITE BROADLY
BIOMEDICAL ENGINEERING WE TEND
TO WANT TO NOT STAY IN OUR LANE
AND IT THE BE CRITICAL HOW
DECISIONS ARE MADE AND
REGULATORY DECISIONS ARE
ULTIMATELY MADE AND I THINK IT'S
A GREAT OPPORTUNITY.
THERE'S BEEN THREE AWARDED
PROJECTS THROUGH THE RFA AND
THEY COVER SOME ISSUES RELATED
TO BIONICS, ROBOTICS AND BIO
PRINTING AND EXO SKELETONS AND
SOME PROGRAM DATES
[AUDIO DIGITIZING]
.
ALBERT DO YOU WANT TO TAKE OVER
WITH THE DRUM ROLL.
I'M HOLDING OFF ON ADVANCING THE
SLIDE.
EVERYBODY'S IN SUSPENSE.
>> I JUST WANT TO SAY THAT
BRUCE'S SUPPORT FOR THIS IS
UNPARALLEL.
THIS IS MY THIRD INSTITUTE I'VE
WORKED AT AND THIS IS
UNPARALLELED.
WE'RE EXCITING.
THE APPLICATIONS FOR THE
INSTITUTIONS TO WRITE THEY'RE
NOT RO1s.
THEY DON'T HAVE ALL THE
INSTITUTION SUPPORT.
SO GETTING THE SUPPORT OF GRANTS
MANAGEMENT TO MAKE THIS AWARD
HAPPEN FOR YOU GUYS TO SEE THIS
COMES TO FRUITION IS AMAZING.
SO WE'RE REALLY EXCITED ABOUT
THIS.
FIRST INSTITUTION AND OTHERS TO
FOLLOW MAYBE BUT GO FOR IT.
>> NO, WAIT.
YOU'RE NOT OFF THE HOOK.
SO TELL US A LITTLE BIT ABOUT
ALBERT SEEING THE ENTIRE
PICTURE.
THIS IS AS ALBERT MENTIONED THE
FIRST INSTITUTION.
THERE COULD BE MORE.
>> DELAWARE STATE UNIVERSITY HIT
IT OUT OF THE PARK.
THEY ARE COMING IN WITH SOME --
WE SET A WIDE SCOPE.
WE DIDN'T DICTATE YOU HAVE TO
CREATE A BIOMARKER ENGINEERING
PROGRAM LIKE FOR OTHER
INSTITUTIONS DID THEY DIDN'T
PARTICIPATE.
THEY'RE TEACHING INSTITUTIONS
AND HAVE MORE HANDS ON.
WE SAID WE'RE GOING TO OPEN IT
UP.
YOU TELL US WHAT FITS YOUR
INSTITUTION.
SO DELAWARE STATE CAME IN WITH
THE THREE PLUS TWO PROGRAM A
THREE YEAR BIO ENGINEERING
DEGREE AND THEN ANOTHER TWO YEAR
PROGRAM AND THEN STUDENTS
PARTICIPATE IN BIOPHOTONICS SO
THEY'RE DEVELOPING A CENTER TO
THEN SUPPORT THE NEW PROGRAM FOR
THE THREE PLUS TWO PROGRAM.
WHICH IS GREAT.
AND IF THE ORGANIZATION SO OUR
HOPE AND I'M GOING TO USE
BRUCE'S WORD WHATEVER IS
DEVELOPED IS EMBEDDED INTO THE
DNA OF THE INSTITUTION AND WE
THINK THEY HIT IT OUT OF THE
PARK.
>> THIS IS AN ENORMOUS AMOUNT OF
EFFORT FROM OUR TEAM AND OUR
COMMUNITY HAS PITCHED IN AND
WE'RE EXCITED.
BUT ALBERT, ONE THING YOU DID
NOT MENTION.
THE NEXT DUE DATE.
BE SURE TO GET THE WORD OUT.
>> BRUCE.
THIS IS ONE OF THE OUTCOMES FROM
COUNCIL.
WE'RE EXCITED ABOUT THIS AND
THANK YOU VERY MUCH, EVERYONE.
>> THANKS, DAVE.
AND THANKS TO COUNCIL.
HOPEFULLY SOME OF OUR WORK GROUP
MEMBERS ARE ON THE LINE OR WE'LL
CONTINUE TO UPDATE EVERYONE BUT
WE'RE PROUD OF THIS.
SO THE NEXT PROGRAM
UPDATE/FUNDING OPPORTUNITY IS IN
BLUE PRINT MED TECK.
WE'VE GIVEN A BRIEF SUMMARY.
IT'S GOT ALL 12 NEUROSCIENCE
RELATED INSTITUTES, THE
BLUEPRINT WORKING TOGETHER AND
REALLY BOUGHT INTO THE IDEA OF
THE KIND OF RAD X ACCELERATION
WITH PROVIDING RESOURCES TO THE
INVESTIGATORS SUCCESSFUL IN
COMPETING FOR THEIR IDEAS.
MAKING THE IDEA ITSELF THE PITCH
FOR THE IDEA IN THE A FULL
PERFECT POLISHED PROPOSAL BUT A
GREAT CONCEPT AND EXCITING
CONCEPT AND SO THE BARRIER TO
ENTRY WE'RE HOPING IS EASIER
THAN TRADITIONAL MECHANISMS.
OF COURSE, IT'S NOT THE SAME IN
TERMS OF STARTING OUT IN TERMS
OF RESOURCES FOR THESE KINDS OF
AWARDS.
SO $37 MILLION IN TOTAL HAS BEEN
AWARDED TO DATE FOR 61 AWARDS.
BUT IF YOU HAVE A GREAT IDEA AND
I THINK NIBIB SEPT OUT A BLAST
E-MAIL ON THIS.
IF YOU HAVE NEURO TECH IN EARLY
STAGES YOU THINK CAN BE
IMPACTFUL AND POTENTIALLY IS
SOMETHING REALLY NEW.
A LOT OF THE EMPHASIS HERE IS ON
DEEFZS THAT COULD BE DEN -- ON
DEVICES THAT COULD BE TRANSFORM
MATIONAL.
THIS IS YOUR PROGRAM CONTACT,
MIKE.
THE IDEA BEHIND THIS IS TO
NURTURE GREAT IDEAS LONG AND
MIKE AND THE MANY I.C. PROGRAM
DIRECTORS THAT ARE ENGAGED WITH
THIS WILL WORK CLOSELY WITH YOU.
SO IT'S A LITTLE DIFFERENT THAN
YOUR TRADITIONAL NIH.
MORE LIKE THE THINGS WE ASPIRE
TO DO AT THE NIBIB.
THE BIG DIFFERENCE IS WE HAVE
ALL 12 BLUEPRINT OR NEUROSCIENCE
INSTITUTES THAT ARE ON BOARD AND
REMAIN ENTHUSIASTIC ABOUT
SUPPORTING THE PROGRAM.
ANOTHER PROGRAM THAT AS AN
INVESTIGATOR IN IMAGING AND
SENSING TECHNOLOGIES, I THOUGHT
WHY CAN'T WE GET NIH TOGETHER TO
REALLY STANDARDIZE, CALIBRATE,
VALIDATE, WE WORK CLOSELY WITH
FDA.
THEY WOULD LOVE TO HAVE THESE
KINDS OF APPROACHES.
BEHIND THE POST SO COME OVER
HERE.
THIS IS HISTORIC.
I DON'T KNOW THERE'S BEEN ANY
KIND OF AWARD LIKE THIS.
THERE ARE 10 AWARDS, NINE
DIFFERENT INSTITUTIONS BEING
MADE IN A VARIETY OF DIFFERENT
TECHNOLOGIES THAT IT'S A LITTLE
BIT OF A DIFFERENT MODEL.
IT'S DESIGN TO BRING PEOPLE AND
COMMUNITIES TOGETHER TO TRY AND
ADVANCE THESE TECHNOLOGIES,
BUILD CONSENSUS AND MOVE THEM
FORWARD TO MORE WIDESPREAD
DISSEMINATION SO THEY CAN IMPACT
PATIENT'S LIVES MORE EFFECTIVELY
AND QUICKLY.
THIS HAS BEEN A LONG LONG EFFORT
FOR YOU THOUGH DIDN'T WE
ANNOUNCE THIS?
IT'S TURNED AROUND AND ONE OF
THE PARTS YOU REMEMBER TWO
COUNCILS AGO I THINK WE TALKED
ABOUT A MULTI-PRONGED APPROACH
IN TERMS OF STANDARDIZATION.
THIS IS ONE WE IMPLEMENTED
SPECIFICALLY RELATED TO P.I.s
WORKING ON STANDARDIZING AND
CREATING DOCUMENT AND SLPs AND
HELPING IN THE COMMUNITY THROUGH
THE CURRENT NIBIB LIBRARY WE
HAVE.
AND ANOTHER IS SPECIFIC TO
OPTICAL IMAGING THEY'RE EXCITED
ABOUT SO BE ON THE LOOKOUT FOR
THAT ONE.
>> LET ME TRANSLATE THAT.
>> THE RESEARCH CONSORTIA.
THE UNIVERSITY PARTNERSHIP
CENTERS AT NSF.
THEY'RE WORKING WITH NSF AND
FDA.
SO THREE OF US WORKING ON
HOPEFULLY FUNDING ONE CENTER
THAT CAN FOCUS AND EXPAND THIS
LATER TO OTHER IMAGING
MODALITIES.
WE ONE THING WE WERE EXCITED
ABOUT AND I WANT TO THANK
SUPPORTERS OF THIS EFFORT YOU
CAN SEE WE HAVE MRI, OCT AND
THIS IS VERY EXCITING.
AND WE WERE EXCITE D TO SEE THE
APPLICATIONS IN THE
ANNOUNCEMENT.
>> THANK YOU.
KEEP AN EYE ON THIS SECTOR.
SOME MAY HAVE TRIED FOR IRCRCs
BEFORE.
WE THINK THROUGH THIS MECHANISM
WITH TOOLS IT CAN BE A VALIDATER
AND IMAGING IS THE FIRST ONE AND
BIO MATERIALS, THE GAUNTLET HAS
BEEN THROWN.
IT'S TIME.
WE'RE EXCITED TO MAKE THAT GO IN
THESE OTHER AREA.
-- AREAS.
TRADITIONALLY, THIS COUNCIL
MEMBERS IS THE TIME WE ANNOUNCE
THE AWARDS.
AND THIS IS AN AMAZING PROGRAM.
ZEYNEP YOU NURTURED THIS FROM
THE BEGINNING.
WHEN I JOINED I THOUGHT WE
NEEDED TO GET ALL INSTITUTES TO
BE PART OF IT AND LOOK WHAT'S
HAPPENED.
WE HAVE MULTIPLE PARTNERS ACROSS
NIH.
WE'LL ANNOUNCE, I HOPE ANOTHER
PARTNER.
WE'RE BUILDING THE SUPPORT.
THIS NOT ONLY HELPS OUR STUDENTS
BUT HELPS RAISE THE VISIBILITY
OF OUR FIELD AND IMPACT NIH.
OUR COLLEAGUES ARE QUITE
ASTOUNDED AS I AM BY THE
PROJECTS SUBMITTED AND WINNING
PROJECTS.
I'LL PAUSE A LITTLE BIT ON
THOSE.
THE TOTAL PURSE IS $116,000.
16 WINNING TEAMS.
IF YOU LOOK AT THE CATEGORIES
THERE'S APPLICATIONS THAT COME
FROM ACROSS THE COUNTRY AND WE
HAD 85 APPLICATIONS, 362
STUDENTS AND 48 UNIVERSITIES AND
24 STATES AND IF YOU THINK
STRATEGICALLY WITH YOUR DESIGN
TEAMS IN THE CATEGORY AREAS
THERE MAY NOT BE A LOT OF AM
APPLICATIONS AND WITH YOUR
DESIGN TEAMS THINK ABOUT THAT.
IT'S NOT JUST MONEY FOR THE
STUDENTS THEY GET ADDITIONAL
SUPPORT FROM NIBIB AND OUR
PROGRAMS.
1: -- THE DEDICATION OF
MENTORSHIP WITH YOUNG PEOPLE IS
WHAT INSPIRED US TO NAME THE
PRIZE AND THIS IS CALLED EURO
FLOW.
IT'S AN ADAPTIVE, AUTOMATED
IRRIGATION SYSTEM FOR
ASSESSMENT.
AND THAT'S ENOUGH SAID TO
SUMMARIZE AND LET YOU HEAR THIS
IS ALWAYS LIKE SUPER IMPRESSIVE.
YOU GUYS EXPERIENCE THAT ALL THE
TIME.
I SORT OF LOST THAT AND SO
WHENEVER I HEAR STUDENTS TALK
ABOUT WHAT THEY'RE WORKING ON
IT'S ASTOUNDING.
FOR OUR ENTIRE COMMUNITY NOT
NECESSARILY FOR COUNCIL YOU'RE
USED TO THIS TYPE OF THING BUT
HERE WE GO.
[NO AUDIO]
>> IT'S SHOCKING THIS WAS NEVER
DONE BEFORE.
IN SOME WAYS IT'S GOOD IT MEANS
OUR STUDENTS ARE SEARCHING OUT
THE PROBLEM SPACES AND HAVE A
GREAT PROCESS AT YOUR CAMPUSES
FOR DISCOVERING WHAT'S IMPORTANT
TO WORK ON.
I'LL RUN THROUGH A FEW MORE OF
THESE WITHOUT THE VIDEOS AND
BRIEFLY MENTION SECOND WIN WENT
WENT TO A TEAM FROM UC RIVERSIDE
AND HAVE A DEVICE OPTIMIZED FOR
VISUALIZATION OF MIDDLE EAR
STRUCTURES AND DYNAMICS.
THIRD PRIZE TO NORTHWESTERN FOR
A CAESAREAN DELIVERY GLOVE AND
THERE WAS $15,000 TO LOYOLA
UNIVERSITY OF CHICAGO FOR AN
INFUSION PUMP MOBILE APP THAT
INTEGRATES CONTENT TO A DIGITAL
SPACE DEVICE.
NIMHD TECHNOLOGIES FOR
LOW-RESOURCE SETTING PRIZE A
$15,000 PRIZE TO CORNELL FOR A
RAPID LOW-COST TEST KIT THAT
UTILIZES GOLD NANO PARTICLES IN
A PERSON'S SALIVA SAMPLE
CONTAINS AN ELEVATED LEAD
CONCENTRATION AND THE PRIZE OF
$15,000 TO STANFORD UNIVERSITY
FOR COLOTECH.
A NEW COST-EFFECTIVE SCREENING
TOOL FOR DYSPLASTIC COLON CELLS.
IT'S A HOLY GRAIL TYPE OF TEST.
WE'LL SOO HAVE TO SEE HOW IT
PROSECUTIONS OVER TIME.
AND NICHD, $15,000 PRIZE IN THE
TECHNOLOGIES FOR A BIONIC NEED
TO THE UNIVERSITY OF UTAH.
IT'S A LOW COST EXTREMITY
PROSTHESIS AND THIS IS A GOOD
EXAMPLE OF A STRATEGIC
POSITIONING.
THIS IS REALLY DESIGN IN
COLLABORATION WITH NURSES SO
FOCUSSED ON APPLICATION FOR IV
POLE REDESIGN TO VIRGINIA TECH
AND HAS MULTIPLE FEATURES
INCORPORATED IN IT THAT ARE
LOGICAL AND I THINK COULD
BENEFIT AND IMMEDIATELY GO TO
MARKET.
NIDDK FOR KIDNEY TECHNOLOGY
DEVELOPMENT GOES TO A TEAM AT
CLEMSON UNIVERSITY WHICH IS A
REAL-TIME DIAGNOSTIC DEVICE TO
RAPIDLY DETECT THE ONSET OF
ACUTE KIDNEY INJURY IN PATIENTS
FOLLOWING CARDIAC SURGERY.
SO THERE'S A SUMMARY OF THESE
AND A BIG AWARD CEREMONY AT THE
NES AND STUDENTS WILL ALL
PRESENT.
IT'S A GREAT TIME TO CELEBRATE
THEIR ACCOMPLISHMENTS AND THE
ACCOMPLISHMENTS OF OUR FIELD AND
ENTIRE COMMUNITY.
WE'VE INTRODUCED A NEW BONE --
BENEFIT TO COMMERCIALIZE
INNOVATION.
NOT ONLY DO THESE STUDENTS NOW
HAVE ACCESS TO THESE RESOURCES
BUT OUR COMMUNICATIONS TEAM HAS
LOOKED AT 10 YEARS OF C3I AND
THE RESULTS ARE ASTOUNDING.
I WANTED TO SHARE THEM WITH YOU.
SO MORE THAN 220 TEAMS HAVE BEEN
TRAINED.
ROUGHLY EQUAL BETWEEN ACADEMIC
AND SMALL BUSINESS TEAMS.
YOU CAN SCAN THE QR CODE FOR THE
ARTICLE THEY PUT TOGETHER THAT
SUMMARIZES ALL OF THIS.
THAT HAVE A -- THEY HAVE A
CONVERSION RATE AND MORE THAN
$6 MILLION MILLION HAVE BEEN
RAISED AND THE PROJECTS HAVE
RESULTED IN SIGNIFICANT DEVICES
OUT THERE IN OUR COMMUNITY,
COMMERCIALLY AVAILABLE BEING
USED.
OVERALL THE PROGRAM IS JUST
BEGINNING.
THIS IS 10 YEARS AGO IF YOU
THINK ABOUT THE DRIVE TOWARDS
COMMERCIALIZATION, IT REALLY WAS
JUST BEGINNING KIND OF THIS
INNOVATION AND ENTREPRENEURSHIP
ACROSS OUR CAMPUSES.
SO THIS IS REALLY AN EXCITING
EXPANDING PROGRAM THAT'S NOW
IMPACTING EVERY LEVEL OF
TRAINING AND SPECTACULARLY
UNDERGRADUATE TRAINING AS THE
THE STUDENT MOVE TOWARDS
COMMERCIALIZATION.
THE PROGRAM ITSELF CONSISTS OF
THREE PHASES.
SO 12 WEEKS ONLINE AND 24 WEEKS
IN AN IN-PERSON BOOT CAMP IF YOU
CHOOSE TO DO THAT AND ANOTHER 12
MONTHS OF POTENTIAL ACCELERATION
WITH ADDITIONAL FUNDING IF YOU
COME INTO IT WITH NIBIB SUPPORT
OTHERS PARTICIPATE BUT IF YOU
HAVE NIBIB SUPPORT YOU MAY BE
ABLE TO GET ADDITIONAL EXPORT
AND TODD, I'M LOOKING AT YOU,
YOU PIONEERED THE PROGRAM.
DO YOU WANT TO SAY A FEW WORDS
ABOUT IT?
I HAVE SOME PICTURES OF AMAZING
PRODUCTS YOU MAY WANT TO COMMENT
ON.
>> I NOTICED FIRST PREDICTIVE
AUDIO MODELLING AND
>> WE'RE EXCITED ABOUT THIS.
AND WE'VE CAREFULLY STRUCTURED
THIS OVER THE YEARS TO HELP
SUPPORT OUR ENTIRE PORTFOLIO
FROM ACADEMICS, RO1s AND MAKING
SURE THERE'S SOME VALUABLE
BUSINESS OPPORTUNITY THERE.
THE CRUX OF THE PROGRAM IS OUR
MENTOR NETWORK.
WE HAVE BUSINESS ADVISORS AND
ENTREPRENEURS AND SUCCESSFUL
BUSINESS EXECUTIVES WHO MENTOR
AND STICK WITH THE TEAMS AND
PROVIDE ON THE GROUND REAL WORLD
EXPERIENCE TO HELP THEM VET
THEIR BUSINESS MODEL.
I THINK THE NUMBERS SPEAK FOR
THEMSELVES BUT WHAT'S NOT
OBVIOUS FROM HERE AND WHAT KEEPS
US MOTIVATED IS THE FEEDBACK WE
GET FROM THE TEAMS AS FAR AS
THEY'RE EXPERIENCE WITH THE
PROGRAM AND HOW GRATEFUL THEY
WERE FOR THESE TYPES OF
OPPORTUNITIES HELPING MOVE THEIR
PRODUCTS FORWARD AND THE
CONNECTIONS THEY MAKE WITH
PARTNERS IS INVALUABLE.
WE'RE UP TO EIGHT OR NINE
INSTITUTES PARTICIPATING IT'S
GREAT TO HUMIDITY AND THANK YOU,
BRUCE.
>> THANKS, TODD.
SO, DO YOU GUYS WANT TO SAY
SOMETHING -- THESE ARE
INCREDIBLE PRODUCTS.
WE HAVE TO COMPILE THESE.
DO ANY OF THESE RING A BELL?
DO YOU WANT TO COMMENT ON ANY
BACK STORIES?
>> SURE.
ONE THAT STICKS OUT IS THE
DEVICE IN THE TOP -- THIRD FROM
THE TOP.
THIS WAS A COMPANY FROM THE
UNIVERSITY OF VIRGINIA.
AN ULTRASOUND DEVICE SUPPORTED
BY NIBIB AND THE FIRST SPIR
PROJECT.
AND WE WERE ABLE TO
COMMERCIALIZE THE DEVICE AND
THIS IS FOR ANESTHESIA GUIDANCE
WITH THE ULTRASOUND DEVICE TO
HELP FIND THE INTRAVERTEBRAL
SPACE FOR DIFFICULT PATIENTS.
THAT'S BEEN ON THE MARKET FOR A
WHILE AND VERY SUCCESSFUL.
I'LL MENTION QUICKLY IMAGING IS
INTERESTING BECAUSE IT WAS OUR
FIRST A.I.-BASED PROJECTS
LOOKING AT THE REDUCTION
ADVANCED COMPUTATIONAL
TECHNIQUES BUT THEY'RE ALL
INTERESTING DEVICES.
THAT'S A QUICK SNAPSHOT OF THOSE
THAT HAVE BEEN ABLE TO GET
REGULATORY CLEARANCE.
>> THERE'S THE BREADTH AND
SCOPE.
IN THE UPPER LEFT HAND X-RAY AND
BIG INSTRUMENTATION.
YOU HAVE THE ASSISTED ANKLE AND
BIO MOLECULAR TOOLS
COMMERCIALIZED AND BEING SOLD.
SCANNING LASER SCOPE.
IT COVERS A BROAD RANGE OF
DEVICES.
AND WITHOUT C3I WE WOULDN'T HAVE
OUR RADX PROGRAMS.
IT'S OUR FOUNDATIONAL
INSPIRATION FOR HOW WE STRUCTURE
WHAT RADX DOES AND THERE'S
SYNERGY BETWEEN THE TWO WITH THE
CONSULTANTS AND ADVISORS OVER
THE YEARS ARE ONES WE CONTINUE
TO ACCESS AND OFTEN TIMES WILL
BRING INTO RADX TYPES OF
OPERATIONS ITSELF.
IT'S BEEN VERY IMPORTANT
FOUNDATIONAL PIECE.
WE DON'T TALK ENOUGH ABOUT IT.
HAVE BEEN SPENDING MORE TIME ON
IT BECAUSE IT'S SO DIFFERENT AND
DOES ENCOMPASS MULTIPLE
INSTITUTES.
SPEAKING OF RADX TYPES OF
PROGRAMS, A QUICK UPDATE ON RADX
TECH, THERE'S A CHALLENGE IN
GETTING IN VITRO DIAGNOSTICS OUT
AND WIDELY DISTRIBUTED.
IN SOME WAYS WITH COVID THE
NATIONAL CRISIS, FDA EMERGENCY
USE AUTHORIZATION I DON'T WANT
TO SAY WAS EASY BUT THE PATHWAY
ITSELF FROM REGULATORY WAS MORE
DIRECT AND THERE'S AN YOU ARE
AGAINST NATIONAL NEED AND SO YOU
COULD SEE THE TECHNOLOGIES WERE
ABLE TO GAIN MOMENTUM AND BE
DRIVEN FORWARD.
THIS IS QUITE HISTORIC.
THIS IS A DE NOVO APPLICATION
WORKING THROUGH OUR I TAP
APPLICATION OR PROGRAM THE
INDEPENDENT TEST ASSESSMENT
PROGRAM ONE OF THE RADX
PROGRAMS.
SO OUR PARTNERSHIP WITH OHT7 WAS
CRITICAL AS THEY BROUGHT INTO
THIS AND COULD ENVISION A RAPID
ACCELERATED PATHWAY TOWARDS
AUTHORIZATION AND WORK WITH US
ON THE ANALYTICAL AND CLINICAL
PROTOCOLS.
YOU COULD SEE THIS IS GOING TO
GO.
IT'S A LANDMARK TYPE OF PROCESS
ADDRESSING SOME OF THE BIGGEST
CHALLENGES IN GETTING A NEW
TECHNOLOGY AUTHORIZED AND FULLY
APPROVED BY THE FDA.
THIS WE HOPE WILL BE PART OF A
BROADER NATIONAL PROGRAM TO
ALLOW TEST TO TREAT SO YOU CAN
TEST THE ACID BASED SENSITIVITY
AT POINT OF CARE, A SINGLE PRICK
BLOOD SAMPLE WITH THE TURNAROUND
TIME OF LESS THAN AN HOUR.
POTENTIALLY IMPACTING UP TO $4
MILLION IN THE UNITED STATES.
COULD BE IMMEDIATELY ENROLLED IN
CURATIVE HELP -- HEP C PROGRAM.
HOPEFULLY IT WILL ROLL OUT WITH
FUNDING FROM CONGRESS BUT THIS
IS THE LEGACY OF OUR EFFORT AND
A TESTAMENT TO MULTIPLE AGENCIES
WITHIN NIH WORKING TOGETHER AND
ACROSS THE FEDERAL GOVERNMENT
WITH SIGNIFICANT SUPPORT FROM
CDC.
A QUICK UPDATE ON THE MIDRC
PROGRAM I WON'T THROUGH ALL THE
NUMBERS BUT TO SAY THEY'RE
CONTINUE TO EXPAND.
THE MEDICAL IMAGING AND DATA
RESOURCE CENTER I THINK IS ONE
OF THE BEST STRUCTURED DATA
REPOSITORIES IN A.I. DEVELOPMENT
TYPES OF ENTITIES WE HAVE IN THE
GOVERNMENT AND WE CONTINUE TO
TRY TO EXPLAIN THE POWER OF A.I.
THROUGH EXPLAINING HOW MIDRC IS
STRUCTURED AND WHAT ITS GOALS
ARE.
RATHER THAN GOING TO TECHNICAL
DETAILS ON WHAT WAS ACCOMPLISHED
I'LL GIVE A SHOUT OUT TO OUR
TEAMS.
SO CONGRESS IS REALLY QUITE
INTERESTED IN A.I., OF COURSE,
AND I DON'T KNOW IF MAYBE SOME
OF YOU HAVE SEEN THERE WAS A PBS
SHORT SERIES ON ASKING A.I.
EXPERTS AND PIONEERS WHAT'S THE
LIKELIHOOD THAT A.I. WILL LEAD
TO A 30% CHANCE THAT A.I. ITSELF
COULD RESULT IN THE ULTIMATE
DESTRUCTION OF THE WORLD AS WE
KNOW IT.
RIGHT NEXT TO CLIMATE CHANGE AND
NUCLEAR HOLOCAUST AND SO FORTH.
THERE'S A LOT OF DIVERSE
OPINIONS AND MISUNDERSTANDING
AND WELL, MAYBE A DEEPER
UNDERSTANDING, DEEPER THAN
PERHAPS WE KNOW ABOUT A.I.
SO WE'RE REALLY ACTIVE.
WE'VE DONE THREE A.I. RELATED
CONGRESSIONAL BRIEFINGS.
THE NATIONAL A.I. RESEARCH
RESOURCE IS KIND OF A TARGET OF
GOVERNMENT SUPPORT AND PEOPLE
GETTING TOGETHER AND DISCUSSING
A.I. AND ITS POSSIBILITIES.
SO THERE WERE TWO DEMO DAYS IN
HOUSE AND SENATE WE ENGAGED AND
PARTICIPATED IN IN ADDITION TO
THESE BRIEFINGS.
I CAN'T OVERSTATE THE IMPORTANCE
OF HAVING MIDRC AS AN EXEMPLAR
DATA REPOSITORY AND A.I.
DISCOVERY ENGINE.
QUESTION, ALL THE A.I. PROBLEMS
ARE NOT LIKE THE STATISTICAL
METHODS WE USE TO ENHANCE SIGNAL
AND CONTRAST OF BACKGROUND AND
SO FORTH BUT THEY ARE
UNDERSTANDABLE AND REALLY CAN BE
TRANSFERRED IN SOME WAYS TO
HELPING PEOPLE APPRECIATE THE
POSITIVE DIRECTIONS OF A.I. AND
WHERE WE HOPE MORE RESOURCES
WILL BE INVESTED.
AND IN TERMS OF CONGRESSIONAL
OUTREACH, ANDY ORGANIZED
CONGRESSIONAL STAFF AND THIS
YEAR WAS ASTOUNDING.
THERE WERE 50 STAFF MEMBERS.
THEY CAME FROM 47 MEMBERS OF
CONGRESS.
I'VE NEVER SEEN SO MANY.
IT'S GOT TO BE A RECORD.
WE'RE SEEING PATTY NODDING.
THEY SPENT A SIGNIFICANT AMOUNT
OF TIME WITH US, FIVE DIFFERENT
DEMOS BOTH FROM OUR INTERNAL
INVESTIGATORS AND WE'RE REALLY
EXCITED TO BE COMMUNICATING THIG
WAY.
IT'S QUITE UNIQUE.
THERE WAS A LOT OF ENTHUSIASM
FROM ALL OF THEM WHO FEEL LIKE
THEY LEARNED SOMETHING NEW FROM
THE EXPERIENCE.
WE DON'T GET TO COMMUNICATE IN
THIS WAY VERY OFTEN.
THESE ARE MEMBERS OF CRITICAL
COMMITTEES AND SUBCOMMITTEES
WHERE THEIR STAFFERS WHO ARE
REPRESENTING MEMBERS FROM
CRITICAL COMMITTEES.
SO THIS IS AN IMPORTANT EFFORT.
FINALLY I'LL MOVE TO TRAINING
AND DISSEMINATION.
WE HAVE SOME IMPORTANT MEETINGS
COMING UP.
THE NCI, NIBIB JOINT MEETING.
THIS IS ON COMPUTATIONAL
MODELLING TO ADVANCE ISOTOPES
FOR RADIO PHARMACEUTICAL
DIAGNOSTICS.
TATTIANA AND MARTIN ARE LEADING
THE EFFORT.
WE HAVE PROSTATE CANCER AND
ANOTHER ONE FOR NEUROENDOCRINE
TUMORS.
THIS IS NOW GOING TO MOVE FAST.
DO YOU HAVE COMMENTS OR
THOUGHTS --
>> THIS IS LED BY DOD AND THE
LABS PRODUCING THE RADIO
ISOTOPES.
WE HELPED DIRECT DIRECT THE
CONFERENCE SO IT INCLUDES THE
DEVELOPMENT NIBIB IS OBVIOUSLY
VERY INVOLVED IN.
NCI IS FUNDAMENTALLY INTERESTED
BECAUSE OF CANCER CARE.
WE THINK THIS IS -- WE HAVE A
BUNCH OF SMEs ORGANIZING THE
FUNCTION AND IT WILL BE IN
WASHINGTON, D.C. AND LOOKING FOR
100 TO 150 ATTENDEES FROM 300
ZOOMING IN.
>> IT'S A GOOD SEGUE TO DIGITAL
TWINS.
WE TALKED ABOUT THE NATIONAL
ACADEMIES REPORT DEFINING
DIGITAL TWINS.
IT'S A BROAD DEFINITION AND FITS
INTO VIRTUALLY ALL THE WORK OUR
COMMUNITY DOES.
WITH BRING AGENCIES AND
INSTITUTES TOGETHER AND WE'RE
HAVING A MEETING AT THE END OF
SEPTEMBER, BEGINNING OF OCTOBER
FOCUSSING INTENSELY ON DIGITAL
TWINS.
THE MODELS, COMPUTATION AND
VALIDATION AND SO FORTH.
I ENCOURAGE AND DOE IS A
PARTICIPANT.
I THINK GRACE HAS ONE FEDERAL
AGENCY THAT HAS INTEREST VERY
MUCH INVOLVED.
THIS IS A NEW MEETING LED BY
JESSICA AND DAVE.
IT'S A WORKSHOP IN BALTIMORE ON
NEUROMORPHIC PRINCIPLES IN BIO
MEDICINE HEALTH CARE.
CHIPS AND SCIENCE.
OUR PARTNERSHIP WITH NSF IS
HELPING DRIVE THIS.
IT'S DESIGN TO BRING TOGETHER
MULTIPLE COMMUNITIES AND
DISCIPLINES TO HELP CREATE NEW
NEURAL TECHNOLOGIES.
IT'S A BIG ASK BUT EVERYONE IS
HOPING FOR NEUROMORPHIC CHIPS.
BETTER PERFORMANCE, NEITHER
EFFICIENT AND MORE ADAPTABLE.
WE'RE ALL HOPING FOR THIS AND
THIS CAN HELP DRIVE IT.
THERE'S FOUR FOCUS SESSIONS.
ONE ON MODULATION AND EPILEPSY
AND CORTICO DISORDERS AND
MACHINE INTERFACES AND THE
NEUROMORPHICS AND MEDICAL
IMAGING AND WEARABLES AND
ANALYSIS.
YOU DON'T NEED TO DESIGN JUST A
NEUROMORPHIC CHIP TO
PARTICIPATE.
IT'S TRYING TO OPEN UP THE
COMMUNITY AND BRING PEOPLE IN
AND DRIVE CONVERSATIONS FORWARD
IN THIS CHALLENGING AREA.
A PARTIAL ANALOG IS SYNTHETIC
BIOLOGY.
THIS IS AGAIN LED BY TUBA AND
NICOLE EVERYONE IS EXCITED AND
BUYING TOO THE TOPIC.
EACH SYNTHETIC BIOLOGY MEET
THERE'S A DIFFERENT THEME.
THIS IS TAKING ON THE CHALLENGE
OF HOW CAN SIM BIOGET TO CLINIC
AND WHAT ARE THE TOOLS WE'RE
DEVELOPING AND HOW CAN WE ACC
ACCELERATE THAT.
AND BEFORE I TURN THIS OVER IS
THE SCIENCE EDUCATION
PARTNERSHIP AWARD.
AND TINA GATLAN IF YOU CAN RAISE
YOUR HAND, THIS IS SOMETHING WE
WENT OVER AND I THOUGHT I
HAVEN'T HEARD OF THIS.
THIS IS AN AMAZING PROGRAM.
WE'RE INVESTED IN SCIENCE
EDUCATION PARTNERSHIPS THAT ARE
IN THE K-12 SPACE AND WE JUST
GAVE TWO AWARDS.
ONE IS GOING TO THE SCIENCE
CENTER IN ITHACA CALLED BIO
BUILDING A TRAVEL EXHIBIT FOR
BIO ENGINEERS.
OUR TEAM DEVELOPED MATERIALS FOR
MIDDLE SCHOOLERS IN BIO
ENGINEERING.
THE SECOND IS AT SAN ANTONIO AND
BUILDING CURRICULA AND DO
OUTREACH AND ENGAGE.
IT'S A GOOD AWARD, 25 MECHANISMS
FOR FIVE YEARS.
YOU CAN'T RENEW BUT IT'S A
SUSTAINABLE TYPE OF FUNDING.
ALL RIGHT, TRAINING AND
DISSEMINATION IN THE BETA
CENTER.
WE HAVE MUYINATU READY TO GO.
>> A LITTLE BIT ABOUT THE CENTER
WE DO EXTRAMURAL.
I'M EXCITED ABOUT THE BELL STATE
WINNING THE FIRST AWARD.
I WENT TO HIGH SCHOOL IN DOVER,
DELAWARE AND IT WAS MY FIRST
ENGINEERING PROGRAM FOR
MINORITIES FROM 6th TO 8th
GRADE.
THAT WAS EXCITING.
FIRST I WANT TO TALK ABOUT
SOMETHING HAPPENING IN THE
INTRAMURAL PROGRAM SPEARHEADED
BY THE ADVANCED IMAGING AND
MICROSCOPY IRP.
THEY DO AMAZING THINGS BUT MAKE
THEM SEEM EASY WE STARTED DOING
IMAGING AND THEY'RE LIKE WAIT IT
WILL TAKE A LONG TIME FOR THE
IMAGE TO LOAD AND THEN FOR US TO
MANIPULATE IT WILL TAKE MORE
TIME AND THEY MAKE IT SOUND
EASY.
WE WERE AWARDED THE NIH
DIRECTOR'S CHALLENGE AWARD.
IT'S PUT UP EVERY TWO YEARS.
THEY PUT MYSELF TOGETHER FROM
NIBIB WITH NINDS AND NIAID AND
ALLERGY AND INFECTIOUS DISEASES
TO PUT TOGETHER THE ATLAS OF THE
SYSTEM IN THE BRAIN AND WHERE IT
GETS IN CONTACT WITH THE SKULL
AND MENINGES.
YOU CAN DO IT WITH FLUORESCENT
IMAGING AND FIRST IS MANAGING
THAT MUCH DATA.
THEY DEVELOPED THE NEURAL
NETWORKS TO TRAIN ONE PART OF
THE IMAGE TO BE APPLIED TO THE
REST OF THE IMAGE TO REDUCE TIME
AND THE NEXT PART IS I'M NOT A
CODER.
I'M SAYING IT PUBLICALLY, SORRY.
BUT THEN TO GET THE A.I.
INTERFACES AND MANIPULATE THE
IMAGES THEY LIKE TO WRITE THE
CODE BUT FOR THE GENERAL
BIOLOGIST YOU WANT THE INTERFACE
AND THE SECOND IS DEVELOPING THE
CODE SO IT'S ACCESSIBLE TO
OTHERS.
IT'S A TOOL WE'RE DEVELOPING IN
HOUSE AND THE ACTUAL OUTPUTS
WILL BE USED BY OTHERS.
SUPER EXCITING THE BLEND OF
NIBIB AND NINDS AND PARTNERING
WITH NCATS IT TURNED OUT THEY
HAD AN ADVANCED PROJECT STARTING
TO DO THIS IMAGE ANALYSIS.
SINCE THE FUNDINGS HAVE BEEN
STARTED THEY'VE BEEN ABLE TO
TAKE A 13 TERABYTE IMAGE AND
WERE ABLE TO SLICE THROUGH IT IN
THE FIRST TWO MONTHS.
THIS IS GOING TO ADDITIONAL
CODERS AND SOFTWARE ENGINEERS
AND TRAINING PEOPLE TO TRAIN THE
MODELS.
WE'RE EXCITED ON EXTRAMURAL
SIDE.
WE HAVE A FULL STAFF WE'D LIKE
TO SAY.
AND THERE'S THE DIRECTOR AND
NICOLE MORGAN AND DEPUTY
DIRECTOR IN THE AUDIENCE AND
CHIEF OF STAFF AND WE BROUGHT IN
TWO NEW TOOLS OR PRINCIPLES AND
COMPUTATIONAL BIOLOGY GUIDE AND
POSTDOC.
BEGINNING TO ROLL THOSE OUT TO
THE REST OF NIH.
WE FINISHED OUR SUMMER PROGRAM I
THINK WE SHARED WITH THE HELPFUL
FUNDS OF IRP REEXPANDED TO 24
INTERNS FROM 16 AND WE EXPANDED
WHO COULD APPLY.
SO OUTSIDE THE THIRD YEAR
BIOMEDICAL ENGINEERING STUDENTS
IN ANY OR ENGINEERING MAJOR
WHICH EXPANDED THE TYPES OF
STUDENTS WE WERE ABLE TO REACH
AND YOU CAN SEE STUDENTS THERE
BUT I WANTED TO FEATURE A
STUDENT IN THEIR LAB AND WE HAVE
A FIRST-YEAR STUDENT.
AND HE'S JUST DONE ONE YEAR IN
COLLEGE WHICH AGAIN MAKES SOME
OF OUR MENTORS NERVOUS BUT HE
BECAME A ROCK STAR AND WAS IN
OUR IDEAS GROUP IN-HOUSE IN
NIBIB BUT A SHARED RESOURCE AND
OVER THE SUMMER -- I LOVE TO
SHOW THIS BECAUSE WE'VE GOTTEN
TO SEE SOME OF THE TECHNOLOGY
AND THIS PLAY NOT PLAY.
THERE'S MULTIPLE USERS THAT CAN
WORK TOGETHER.
VOICE COMMAND TO CONTROL THE
SIZE AND KOL -- COLORS AND
THEY'RE WEARING THE GOGGLES AND
IT'S ALL HAND MANIPULATED AND
REMINDED ME OF THE MINORITY
REPORT AND THIS IS WHAT APPEARS
WHEN HE RAISES HIS HANDS.
HE EXPANDS THE MULTI-USER
CAPABILITY AND HE'S A FIRST-YEAR
COLLEGE STUDENT.
THERE'S BENEFITS OF OPENING UP
THE PROGRAM TO OTHERS.
AND YOU HEARD US TALK ABOUT THIS
TOGETHER.
WE'RE CLOSER AND LIKE DAVID AND
THE OTHERS, WE'RE HOLDING BACK
ON THE NIH CAMPUS THE BUILDING
BRIDGES FOR THE BROADER
ENGINEERING COMMUNITY.
ONE OF THE GOALS IS TO ACROSS
INTRAMURAL WITH EXTRAMURAL AND
YOU CAN COLLABORATE WITH US AND
WORK WITH US AND WANT YOU TO SEE
WHAT OUR CLINICIANS ARE DOING ON
CAMPUS.
THERE'S INTRAMURAL AND WE HAVE
OUR SPEAKER ONE OF THE PIONEERS
FOR SICKLE CELL DISEASE AND
WE'RE SUPER EXCITED THAT NIH
DIRECTOR DR. MONICA BERTAGNOLLI
WILL DO A WELCOME FOR US AND OUR
LOVELY PROGRAM DIRECTORS ARE
THERE AND WE HAVE 450 PEOPLE
REGISTERED AND 180 ABSTRACTS SO
HOPE TO SEE YOU ALL THERE.
>> SO THAT'S THE LAST OF THE
PRESENTATION AND SO WE HAVE TIME
TO TAKE QUESTIONS NOW BEFORE
ZEYNEP'S PRESENTATION.
>> PART OF THE STRUCTURE BEHIND
BETA CENTER AND THE MEETING AND
FOR A LOT OF WHAT WE'RE TRYING
TO DO IT STRUCK ME NIBIB WAS A
WELL KEPT SECRET.
I SUSPECTED THAT BUT DIDN'T KNOW
FOR SURE.
WE'RE MOVING IN A POSITIVE
DIRECTION.
WE'RE OPENING IT UP.
ANY QUESTION YOU'VE GOT, OUR
PROGRAM TEAM HERE, MANU'S HERE,
OUR INTRAMURAL FOLKS AND
SCIENTIFIC DIRECTOR, RICHARD, IS
HERE.
IS THERE A PLANT FROM THE
AUDIENCE?
>> I CAN START.
>> SO FIRST OF ALL, IT'S REALLY
INCREDIBLE YOU AND YOUR STAFF.
EVERY TIME YOU THINK YOU JUST
RAISE THE BAR EVEN HIGHER.
IT'S INCREDIBLE.
SO I DO HAVE A QUESTION.
SO I THINK YOU DON'T HAVE TO
CONVINCE US HERE IN THE ROOM BUT
I'M CURIOUS I THINK IT'S GREAT
HAVING LIKE THE A AND B STAFF
AND THE CONGRESSIONAL BRIEFINGS
WITH THE SENATE AND HOUSE.
I'M CURIOUS HOW MUCH FOLLOW-UP
AND MORE TOUCHES BECAUSE AS YOU
MENTIONED I THINK ONE OF YOUR
EARLIER SLIDES SHOWED THE
APPROPRIATIONS.
I'M WONDERING HOW MUCH.
I KNOW THERE'S LAWS ON HOW YOU
CAN'T MAYBE INTERACT AND THERE'S
CERTAIN WAYS BUT I'M CURIOUS ON
HOW SHOWING THE RESULTS AND
PRODUCTS HOW MUCH IS BEING DONE
OR ALLOWED TO DO.
I'M CURIOUS THAT KIND OF
INTERACTION.
>> IT'S A GREAT QUESTION.
IT'S NOT SOMETHING THAT --
THERE'S NO SPECIFIC RULES
WRITTEN DOWN OF DO THESE THINGS
AND THEN YOUR INSTITUTE WILL GET
AN INCREASED APPROPRIATION.
THERE'S NO CAUSALITY OR SPECIFIC
PLAYBOOK OTHER THAN TRYING TO
TAKE EVERY OPPORTUNITY WE HAVE
TO TRY AND PROMOTE AND PUBLICIZE
THE WORK OF OUR COMMUNITY
COLLECTIVELY.
SO OUR GOAL WORKING WITH THE
ACADEMY FOR IMAGING AND
INDIVIDUAL PROFESSIONAL
SOCIETIES IS TO KEEP THE
CONVERSATION AND DIALOGUE GOING.
WE CAN BECOME AN EPICENTER FOR
EVENTS TO BRING PEOPLE IN AND
DISSEMINATE INFORMATION AND
THAT'S WHAT THE COUNCIL MEETING
IS FOR BUT CONTINUING TO FOLLOW
UP, I THINK THAT BALL HAS TO BE
CARRIED BY THE PROFESSIONAL
SOCIETIES AND INDIVIDUAL
SCIENTISTS AND INVESTIGATORS
THEMSELVES.
SO WE CAN CONTINUE TO CREATE
CONTENT AND ABBY, CHRIS, DO YOU
GUYS WANT TO COMMENT ON THAT?
THIS IS A BIG PART OF WHAT OUR
COMMUNICATIONS TEAM DOES AND
LEGISLATIVE POLICY AS WELL.
THERE'S AN.
CHAIR OVER THERE.
-- OPEN CHAIR OVER THERE.
IT'S INTERESTING BECAUSE IF WE
WERE THE HEART INSTITUTE WE
WOULDN'T HAVE TO DO THESE TYPES
OF THINGS BUT HAVE SIMILAR
CHALLENGES WITHIN YOUR
INSTITUTIONS.
>> IT'S JUST TELLING THE STORIES
OVER AND OVER AGAIN.
YOU TRY TO BE DISEASE AGNOSTIC
AND YOU CAN SEE HOW TECHNOLOGIES
CAN BENEFIT PEOPLE DOWN THE
ROAD, SAVE MONEY, IMPROVE
OUTCOMES.
IT'S REALLY EVERYONE TELLING THE
GREAT STORIES WE HAVE.
AND DAWN IS HERE.
SHE CAN PROBABLY OFFER SOME
ADVICE AFTERWARD.
>> CAN YOU GRAB THE SEAT AND
FOLLOW UP A LITTLE BIT?
THAT WAS AN INCREDIBLE EVENT.
FIRST, WE NEVER KNOW.
THERE'S LIKE THE BUSSES ARE
LEAVING.
HOW MANY PEOPLE ARE ON THE
BUSSES?
AND THERE WERE 50 PEOPLE ON THE
BUSSES SO YOU GUYS DID SOMETHING
WRITE THERE.
>> THANKS, BRUCE.
THAT WAS A RECORD SETTING EVENT.
WE HAVEN'T HAD THAT MANY
STAFFERS IN THE PAST.
WE'RE EXCITED AND FOR SOME OF
THAT FOLLOW UP TO ANSWER THE
QUESTION, WE HAVE A LOT OF
FOLLOW UP BEHIND THE SCENES
AFTER THAT SO TAKING MEETINGS
WITH STAFFERS WHO CAME, WHETHER
WE'RE GOING OUT TO THEM SAYING
YOU'RE HERE AND YOU LIKE WHAT
YOU SAW WE HAVE CONSTITUENTS WHO
HAPPEN TO BE FELLOWS AND HAVE
CONSTITUENTS AND FELLOWS.
MOST THE TIME IT'S US BEING
PROACTIVE GETTING THE MEETINGS
AND NOT NECESSARY THEM HAVING
QUESTIONS BUT WE HAVE HAD
SEVERAL TIMES IN PAST MAYBE
MONTHS LATER YOU ALL ARE A
TRUSTED RESOURCE.
SO BUILDING THAT CONNECTION,
COMING TO CAMPUS, SEEING
SOMETHING AND LATER WORKING ON
RELATED TOPIC, THEY KNOW TO
REACH OUT.
OBVIOUSLY WE THINK IT'S A REALLY
CRUCIAL TIME TO MAKE THOSE
CONNECTIONS MORE SO THAN EVER.
SO WE'RE HAPPY THAT YOU HAVE
THIS CONTENT WE CAN SHARE WITH
THEM AND MAKE CONNECTIONS AND
HAVE MEETINGS WHERE WE'RE
INVITING YOU ALL.
SO LOTS OF FOLLOW UP.
>> AND I THINK ALSO I KNOW THIS
IS NOT AT THE CONGRESSIONAL
LEVEL BUT OTHER AGENCIES
PARTICULARLY WITHIN HHS
APPRECIATE THE KINDS OF
CONTRIBUTIONS OUR COMMUNITY
MAKES.
HAVING CONSIDERED THE DRIVING
FORCE OF THE TECHNOLOGY
DEVELOPMENT TO BE AS IMPORTANT
AS THEIR APPLICATION FOCUS AREAS
BUT AS THEY'VE SEEN THROUGH
PARTNERSHIPS, YOU CAN'T GET
STUFF DONE WITHOUT SOME NEW
APPROACH.
IT'S INTERESTING A.I. AND THE
EXPANSION INITIATED A SERIES OF
QUESTIONS AND WE'RE ABLE TO STEP
IN AS PEOPLE TALK ABOUT
DATABASES AND JUST SAYING WHERE
DID YOUR DATA COME FROM?
IT PROBABLY CAME FROM SOME KIND
OF A DEVICE OF SOME SORT AND
GUESS WHAT, YOU CAN'T JUST
AGGREGATE ALL DEVICES WITH A
COMMON NAME.
THEY'RE NOT NECESSARILY ALL
WORKING THE SAME.
SO IT'S LIKE AN ENTRY WAY INTO A
DIALOGUE HOW TO ENSURE ETHICAL
AND TRUE SOLUTIONS FROM
A.I.-BASED APPROACHES BECAUSE
EVERYONE HAS GONE NUTS OVER IT.
IT'S THE INFINITE POSSIBILITY
AND I GUESS 30% CHANCE IT WILL
DESTROY THE WORLD.
I HAVE TO GET THAT QUOTE FROM
PBS.
IT'S REMARKABLE.
DAN.
>> TO STICK ON THE STORY TELLING
THEME FOR A SECOND.
I THINK ALL THE ACTIVITIES WE
HEARD ABOUT ARE GREAT.
YOU THEN CHALLENGED US, IT'S UP
TO YOU TO TELL OUR STORY.
IN THE MODERN WORLD WE'RE
FLOODED WITH STORIES.
I'M NOT SURE THE PROBLEM IS
TELLING THE STORIES.
I THINK THE PROBLEM IS
AMPLIFYING AND CONSOLIDATING AND
MAKING THEM HIT HOME AND IF
NIBIB WERE A TECH COMPANY WE'D
SEE ADVERTISEMENTS.
WE SEE THEM ALL THE TIME FOR THE
APPLE PHONE.
NO ONE QUESTIONS THE VALUE OF
TECH IN OUR LIVES IS THERE
THOUGHT OF MORE COORDINATED --
BECAUSE IN SOME WAYS IT'S A
MESSAGE TO HAVE FILTER AND WOULD
BE GREAT TO HAVE A STRATEGIC
MESSAGE DELIVERED FROM MULTIPLE
ANGLES.
>> YEAH, THIS IS A REALLY
INTERESTING POINT.
WHAT'S GOING THROUGH THE MIND OF
ALL OF THE NIH LEADERSHIP AND
CHRIS, YOU MAY BE ABLE TO
COMMENT ON THE RETHINKING OF
BRANDING NIH.
SO WE HAVE A PRESENTATION FROM
OUR LEGISLATIVE POLICY AND
COMMUNICATIONS TEAM THE UBER
TEAM FOR ALL OF NIH AND THEY
POINTED OUT PEOPLE ARE VAKE AND
WE HAVE SUB BRANDS CONFUSING AND
LOGOS MIXED UP AND COMPARED US
TO NASA, WHICH IS NOT REALLY
FAIR.
THEY GO TO GREAT LENGTHS TO
MAINTAIN THE BRAND IDENTITY AND
EVERYTHING IS COMPLIANT WITH THE
NASA PUBLICITY.
THE WAY THEY PROMOTE THEMSELVES.
WE'RE A REFLECTION OF THE
BIOMEDICAL RESEARCH AND GOES IN
SO MANY TOPICS BUT SPACE IS
INFINITE TOO.
I DON'T KNOW.
IT'S A GOOD QUESTION AND AS OUR
STRATEGIC PLAN IS ROLLING OUT, I
DIDN'T HIT THE GO ON THE WEBSITE
YET BECAUSE I DIDN'T WANT TO
OVERWHELM EVERYONE WITH TOO MUCH
CONTENT BUT WE'LL HIT THAT VERY
SOON AND WE'LL HAVE MORE
DISCUSSIONS WITH COUNCIL ON HOW
TO DO THAT.
THAT'S A BIG QUESTION.
THE WHOLE NIH IS THINKING AND I
SHOULD BRING UP AND TOOK THE
SLIDE OUT BECAUSE I HAVE TOO
MANY SLIDES BUT IT'S AN
INTERESTING STATISTIC.
WE KEEP TRACK, WE KEEP SCORE.
ONE OF THE FIRST THINGS TODD
GENERATED IS I WANT YOU TO KNOW
HOW MUCH ALL OF NIH SPENDS IN
BIO ENGINEERING IT ENCOMPASSES
ALMOST ALL IMAGING.
WE STARTED I THINK AT 13%.
IT'S UP TO 15% OF THE ENTIRE NIH
BUDGET IN 2023.
$7 BILLION.
SO THAT'S A PRETTY ASTOUNDING
FIGURE.
NOT THAT MANY PEOPLE REALLY
THINK OF NIH AS A TECHNICAL
ACTION.
BUT OVER ALL, 27 INSTITUTES,
CENTERS AND OFFICES OVER $7
MILLION IN A YEAR SPENT ON
TECHNOLOGIES.
SO WE'RE TRULY A TECHNOLOGY
INTENSIVE INSTITUTE.
SOMEHOW WE HAVE TO CAPTURE
YOU'RE PROBABLY I DON'T KNOW
THERE MAY BE LIKE 200 PEOPLE
THAT KNOW THAT IT'S $7 BILLION
BUT I TRY TO PROMOTE THAT.
YOU GUYS CAN PASS IT ON.
I'M DELIGHTED TO SEE MUCH OF THE
FOCUS ON DEVELOPING THE SCIENCE
OF BIOENGINEERING TECHNOLOGIES
ACROSS THE INSTITUTES.
AND WHAT'S IMPORTANT IS WHERE DO
WE GET THE SCIENCE AND TOOL AND
ENGINEER IN BIOLOGY TOMORROW AND
THAT I THINK IS A GREAT THING TO
HEAR FROM YOU AS YOU'VE SPOKEN
TODAY.
>> WE'RE THE ONE INSTITUTE THAT
DOESN'T CARE IF YOU DON'T HAVE A
DRIVING BIOMEDICAL HYPOTHESIS.
IT'S OUR UNIQUE CLAIM TO FAME.
YOU CAN SEE THE IMPACT IT'S 15%
OF THE BUCKET, $7 MILLION.
WE'RE KIND OF THE KERNEL FOR
EXPANSION.
YOU CAN TRACE MANY TECHNOLOGIES
THAT ARE SUPPORTED BY OTHER
INSTITUTES AND CENTERS BACK TO
SOME OF THE EARLY FORMATIVE
DRIVING WORK WE'VE SUPPORTED.
BUT IT'S A REALLY POSITIVE
FEATURE AND WE HOPE OUR
COMMUNITY AND IT'S EASIER FOR US
TO FORM PARTNERSHIPS FROM OUR
BROTHER AND SISTER AGENCIES THAN
IT IS TO EXTRACT IT WITH A
CONGRESSIONAL APPROPRIATION.
I WANTED TO MAKE SURE THOSE
RESOURCES AND A WONDERFUL
EXAMPLE IS ARPA-H.
SO SOME INSTITUTES HAVE A MORE
DIFFICULT TIME WORKING WITH
ARPA-H.
MANY OF OUR PROGRAM DIRECTORS
PROBABLY A SHOW OF HANDS IF YOU
WORKED WITH ARPA-H REALLY
EXTENSIVE VERY CLOSE CONNECTION.
I SHOULD NOTE AND I'LL PROBABLY
DEVELOP A NEW SLIDE ON THIS THE
PRECISION GUIDED SURGICAL
INITIATIVE LIKE $120 MILLION,
$130 MILLION INITIATIVE THEY
ANNOUNCED I THINK NINE AWARDEES.
THEY'RE ALL BIOMEDICAL
ENGINEERING, IMAGING PEOPLE WE
HAVE SUPPORTED.
EVERY ONE OF THESE ARE IN OPTICS
USING CUTTING EDGE APPROACHES.
BUT THESE ARE THINGS OUR
COMMUNITY HAS BEEN WORKING ON
DECADES.
THEY JUST ARE NOT SUDDENLY NEW.
AND THE OPPORTUNITY FOR ARPA-H.
WE COULD NEVER COME UP WITH $120
MILLION TO SUDDENLY GET THE
SEARCH.
IT WILL MAKE A DIFFERENCE.
IT WILL FINALLY ACCELERATE THE
BEAUTIFUL TECHNOLOGIES OUT OF
LABORATORIES AND BOUTIQUES AND
CONSORTIA WITH COMMERCIALIZING
AND EXPANSION SO PATIENTS CAN
BENEFIT AROUND THE WORLD.
THEY'RE TACKLING THAT WITH THE
NEW INITIATIVE THAT'S ABOUT TO
COME OUT THAT WILL SUPPORT SOME
OF THE DATA THAT WILL BE
GENERATED THROUGH THOSE
PRECISION-GUIDED SURGICAL
TECHNOLOGIES.
WE WORK CLOSELY WITH THEM AND
IT'S A WONDERFUL PARTNERSHIP.
OTHER INSTITUTES DON'T HAVE THAT
LUXURY BECAUSE THEY FEEL LIKE
MAYBE THEY'RE COMPETING MORE
WITH ARPA-H SOMETIMES BUT FOR US
IT'S COMPLIMENTARY.
>> I THINK IT'S AMAZING YOU HAVE
A GREAT PARTNERSHIP BUT I DO
THINK IN TELLING THE STORY IT
SHOULD BE EMPHASIZED AT SOME
JUNCTURE THAT A LOT OF THE
UNDERPINNING TECHNOLOGY THAT
ARPA-H IS DRIVING FORWARD WAS
BECAUSE OF NIBIB.
I THINK THAT MAYBE LETS LOST.
THERE'S TECHNOLOGY PEOPLE VERSUS
WHAT HAS HAPPENED FOR DECADES
HERE.
I WAS TRYING TO THINK ABOUT WHY
DOES EVERYONE KNOW NASA VERSUS
NIH.
A LOT OF IT HAPPENS VERY EARLY
ON IN THE EDUCATIONAL SYSTEM.
SO I THINK IT'S ACTUALLY VERY
GREAT THAT YOU'RE STARTING TO GO
INTO K-12 AND TO THAT COMMUNITY.
WHEN YOU'RE INTERESTED IN
SCIENCE AS A KID YOU THOUGHT
NASA WAS THE THING YOU LEARNED
ABOUT.
THINKING HOW DO WE CREATIVELY, I
DON'T KNOW IF IT'S NIH OR NIBIB
AND IF YOU'RE PASSIONATE ABOUT
MEDICAL SCIENCE THIS IS
SOMETHING TO KEEP YOU'RE EYE ON
IN HIGH SCHOOL OR MIDDLE SCHOOL.
AND ONE QUESTION ABOUT THE
AMAZING HBCU PARTNERSHIP AS THAT
GETS FUNDED TO MAKE THE SUPPORT
STRUCTURE TO ALLOW THAT TO
STRIVE BEYOND THE FUNDING AND
FOR BEST PRACTICES TO THEN BE
TRANSLATED TO OTHER INSTITUTIONS
AND BE ABLE TO LEARN FROM THAT.
>> FIRST OF ALL YOU HAVE TO COME
INTO OUR PR DEPARTMENT AND HELP
US START WITH THIS BRANDING AND
PROMOTION BUT WE LOOK FORWARD TO
WORKING IN A PRACTICAL WAY WITH
YOU AND COUNCIL ON EXACTLY THOSE
KINDS OF IDEAS AND IF THERE ARE
INITIATIVES AND POTENTIAL
LEVERAGING POINTS WITHIN YOUR
INSTITUTIONS AND WITH US, THINGS
WE CAN HIGHLIGHT WITH ALL OF
YOU, THIS IS REALLY THE KEY
BECAUSE THIS KIND OF HELPS
PROPAGATE THE MESSAGE.
I GUESS WE NEED TO GET COOL
UNIFORMS.
WE WOULD LIKE TO SEE THE
INITIATION IS HBCU'S HAVE BEEN
LEFT BEHIND THE REVOLUTION FROM
AN ACADEMIC POINT OF VIEW AND WE
NEED TO BE AT THE FOREFRONT OF
VIGILANCE AND PARTNER AND THINK
THROUGH HOW TO BUILD THE
PARTNERSHIPS AS WELL.
>> SUSTAINABILITY IS THE WORD I
USE IN THE NOFO SO MUCH.
EVERY TIME I TALK TO SOMEONE WE
TALK ABOUT SUSTAINABILITY.
AND DOESN'T HAVE TO JUST BE A
DOLLAR SIGN BUT FACULTY.
ONE OF THE THINGS THAT WE WROTE
IN HERE IS SUPPORTING FACULTY TO
APPLY FOR NIH GRANTS.
ONCE THEY START GETTING THE
FUNDING CAN LEAD TO MORE GRAD
STUDENTS AND THINGS LIKE THAT.
THAT FACULTY DEVELOPMENT PIECE
IS REALLY IMPORTANT FOR THE
SUSTAINABILITY.
ANOTHER ASPECT SO IF YOU'RE
DEVELOPING A PROGRAM, WHAT'S THE
LONG-TERM SUPPORT OF THE
INSTITUTION IN TERMS OF
LEADERSHIP.
IF THE P.I. LEADS IS THE PROGRAM
GOING TO FALL A PART?
I'M LOOKING AT THAT.
OUR TEAM IS LOOKING AT THAT AND
EVALUATING THAT TO MAKE SURE
THAT'S INCORPORATED.
THOSE ARE COUPLE IN TERMS OF THE
SUSTAINABILITY PIECE WHY ARE
IMPORTANT ESPECIALLY THE FACULTY
DEVELOPMENT.
I TELL THEM ALL, LOOK, I CAN GO
TO YOUR INSTITUTION AND WE CAN
HAVE A COUPLE DAYS WHERE WE TALK
ABOUT PRECISION GRANT WRITING
WHERE ARE YOU READY FOR A NEW
INVESTIGATOR OR A REWARD OR FOR
THE DIVERSITY AT NIH GRANT.
WE COULD TALK ABOUT THAT.
THESE ARE SERVICES I OFFER.
IN TERMS OF MODELLING I THINK AT
THE NEXT EMES MEETING WE WEREN'T
READY FOR THIS ONE OBVIOUSLY BUT
WE WERE THINKING MAYBE AT THE
NEXT ONE BRINGING AWARDEES IF
IT'S PLURAL TOGETHER AND
INVITING OTHER HBCUs.
THERE'S THE GOVERNMENT HBCU
MEETING LAST YEAR OR THIS YEAR
IN D.C. WAS WELL ATTENDED BUT WE
HAVE TO BRING THESE HBCUs
TOGETHER.
NOT ALL 102 HBCUs WILL BE ABLE
TO DO THIS AND I'VE GOTTEN
QUESTIONS FROM TCUs THAT WANT TO
PARTICIPATE.
THERE'S CONVERSATION THAT'S COME
UP ABOUT OUR CONGRESSIONAL
BUDGET AND THERE'S ALWAYS THAT
IN THE BACK OF MY MIND.
SO BRUCE HAS BEEN VERY GENEROUS.
WE'RE HOPING AS THIS GETS
ROLLING OUT WE CAN GET A PARTNER
FROM OUR SISTER AND BROTHER
I.C.s TO BUILD THIS UP.
I'M VERY BIG ON THE QUESTION OF
GETTING OUR NAME OUT THERE.
I HAVE NO PROBLEM TOOTING OUR
OWN HORNS.
SAYING COME ON, LET'S GO IT.
I THINK WHAT NASA HAS DONE
THROUGHOUT THE LAST THREE
DECADES IS THEY HAVE PROMOTIONAL
ITEMS AND NIH GOT SLAMMED FOR
THAT.
WE USED TO BE ABLE TO GIVE SO
MUCH OF THE KIDS AND MY KIDS
GREW UP KNOWING NOTHING ABOUT
NIH BUT HAVE NASA BACKPACKS AND
STICKERS.
THANKS FOR THE QUESTION.
RAPHAEL.
>> I KNOW YOU DIDN'T INVITE ME
HERE TO COMPLIMENT YOU THE WHOLE
TIME.
BUT SOME PEOPLE WONDER WHY IS
NIH INVOLVED IN THIS KIND OF
THING?
AND WHERE DO YOU GET THAT
TECHNOLOGY.
IT'S DRILLED IN OUR ECONOMY.
WE'RE RESPONSIBLE FOR 105 IN
ADDITION TO OUR ECONOMY SINCE
1980 BUT AND IT'S SUPPORTING
SOME OF THOSE LIKE RAPHAEL
WANTED TO BRING HBCU THING AND
INNOVATION CENTERS.
THIS KIND OF THING IS THE ONLY
WAY YOU'LL GET TO 10.$4 TRILLION
AND BENEFITS FROM THIS KIND OF
THING.
ANYWAY -- IT'S NICE TO SEE
YOU'RE INVOLVED IN THIS.
>> THANKS, RAPHAEL.
IT'S SUCH A GREAT POINT.
THIS IS WOVEN INTO OUR
INITIATIVE.
THE IDEA THAT OUR COMMUNITY HAS
BUILT THE INNOVATION AND
ENTREPRENEURSHIP THAT CHANGED
THE LANDSCAPE OF THE COUNTRY.
I WAS SLIGHTLY CORRECTED LAST
NIGHT WHEN I SAID I THINK EVERY
B AND E FACULTY MEMBER HAS AT
LEAST ONE START UP AND THEY SAID
WOE DON'T HAVE START-UPS BUT
GOING DEEPER.
YOU GUYS ARE ALL INVOLVED
SOMEHOW IN ADVISING AND WORKING
AND THAT ACTIVITY AND SPIRIT
DRIVE IDEAS MOVING FORWARD AND
GETTING THEM DISSEMINATED.
THERE'S AN ACCELERATOR POPULATED
FROM PEOPLE THAT COME FROM OUR
COMMUNITY AND STUDENTS AND YOU
CAN SEE WHAT THEY'RE DOING AND
THEY'RE TANGIBLE SOLUTIONS TO
PROBLEMS.
WE WANTED TO GET THAT SPIRIT
GOING AND THESE IS IN
ANTICIPATION OF THE PROGRAMS FOR
SURE.
HOPEFULLY WE'LL CATCH ON MORE
BROADLY.
IN ADDITION LIKE WE DO WHAT WE
CAN WITH WHAT WE HAVE.
WE'RE NOT SHY ABOUT GOING AROUND
TO OTHER INSTITUTES AND CENTERS
AND SAYING YOU GUYS CAN INVEST
IN THIS AS WELL.
YOU CAN PARTNER WITH US.
WE'RE SEEING THAT THE DATE YOU
PROGRAM HAS IT'S OWN INTRINSIC
BEAUTY OF COURSE AND HAS A WAY
OF EXTENDING OUR IMPACT AND
COMMUNICATIONS TO OTHER
INSTITUTES AND CENTERS AND
THEY'RE ASTOUNDED.
WE'RE EXCITED BUT WE'RE NOT
SHOCKED ANYMORE.
THEY'RE GOING OH, MY GOD, AND
UNDERGRADS ARE DOING THIS STUFF?
IT'S A VERY IMPORTANT OUTREACH
TYPE OF PROGRAM TO HELP CHANGE
HEARTS AND MINDS.
>> IT'S HITTING HOPE TO WHAT I
HAVE FELT THE NEEDS ARE.
AND SO I FEEL THE UNDERSTANDING
OF THE COMMUNITY AND THE
DIFFERENT PROGRAMS A PROGRAM TO
CREATE PHANTOM IS INTUITIVE.
YOU HEARD THAT NEED FROM
SOMEWHERE AND RESPONDED.
THREES A WHOLE BUNCH OF THESE
THINGS.
I'VE GOT GOOD EAVESDROPPERS IN
PLA
PLACES.
>> WE'VE ALL GROWN UP IN THE
SAME ENVIRONMENT AND COMMUNITY
AND HAVE A GOOD NETWORK OF
COMMUNICATION.
KEEP COMMUNICATING WITH US.
I CERTAINLY HAVE BEEN IN THE
EXTRAMURAL COMMUNITY EXPERIENCED
LIKE YOU GUYS MANY OF THESE
FRUSTRATIONS THINKING WHY
DOESN'T THE NIH DO THIS AND IT'S
BUILT WITHOUT THE STRUCTURE OF
KNOWING WHAT OUR TECHNOLOGY
DEPARTMENT DO AND WE'RE TRYING
TO MOVE FORWARD WITH
COMPATIBILITY MUCH DESIGN, TEST,
DEPLOY, OUR PROCESS.
THE REGULAR OLD RO1s ARE
FANTASTIC BUNT WE NEED
OPPORTUNITIES TO GET SHOTS ON
GOAL AND MOVE THINGS FORWARD.
AND I'M ASTOUNDED THAT THE
OFFICE OF DATA SCIENCE HAS
SUPPORTED SOFTWARE ENGINEERING
AND SOFTWARE.
THIS IS A REFLECTION OF THE
SIGNAL WE'RE PROPAGATING AND
OTHERS ARE INCREASINGLY
PROPAGATE
PROPAGATING AND THEY UNDERSTAND
THE CHALLENGES.
THANKS, CYNTHIA.
>> THERE'S A NEED THAT'S
OCCURRED TO ME AND COME FROM
CONVERSATIONS WITH JUNIOR
FACULTY MEMBERS.
YOU'RE RIGHTLY PRIORITIZING
EARLY STAGE INVESTIGATORS.
YOU HAVE A GENEROUS PAY LINE FOR
THE FIRST RO1 BUT ONE RO1 DOES
NOT TURN A JUNIOR INVESTIGATOR
INTO A SECOND INVESTIGATOR.
I THINK YOU'VE SHIFT THE PROBLEM
TO THE SECOND RO1.
I WONDER IF THE MECHANISMS THAT
MIGHT HELP.
I SAW IN ONE OF YOUR OTHER
SLIDES YOU TALKED ABOUT PLANNING
GRANTS IN PEER REVIEW.
I WONDER IF SOMETHING LIKE THAT
OR ORIGIN FUNDING OR MORE
RELATED PAY LINE FOR JUNIOR
INVESTIGATORS MAY BE SOMETHING
TO THINK ABOUT BECAUSE I KNOW
SOME PEOPLE STRUGGLE ON THAT
RO1.
>> THAT'S A GOOD POINT.
DAVE, MAYBE YOU WANT TO COMMENT.
IT'S SOMETHING THAT WE'RE
THINKING ABOUT A LOT.
>> BRUCE BROUGHT THIS UP AND WE
HEARD NIS FROM THIS COMMUNITIES
AND THERE'S A NUMBER OF
RENEWALS.
WE'RE LARGER THE MESSAGE AND
WE'LL DEFINITELY TAKE A LOOK AND
GET BACK TO YOU WITH MORE
INFORMATION AND ASSESSMENT.
>> WE OFTEN TALK ABOUT EXPANDING
AND WANT TO GET ADVANTAGE.
OUR STRUCTURE IS WE'RE PRETTY
SMALL AND HAVE A PRETTY TIGHT
COMMUNITY.
THERE'S NOT A LOT OF LAYERED
STRUCTURES BETWEEN YOU AS AN
INVESTIGATOR AND PROGRAM
DIRECTORS WHO UNDERSTAND WHERE
YOU ARE AND WHAT YOUR NEEDS ARE.
SO OUR PROGRAM DIRECTORS ARE
EXPERTS AND THEY'LL WORK WITH
ADVOCATORS IN A CHALLENGING --
OUR PHILOSOPHY IS WE'RE NOT SO
BIG AS TO BE UNREACHABLE AND
UNCAPABLE OF UNDERSTANDING
DIFFICULTIES FOR OUR
INVESTIGATORS AND WANT TO KNOW
ABOUT THE CHALLENGES.
THERE'S FLEXIBILITIES WE CAN
INTRODUCE BECAUSE WE DON'T WANT
PEOPLE TO GO OUT OF BUSINESS.
[OFF-MIC]
>> YOU DON'T GET FUNDING IF YOU
DON'T TALK TO A PROGRAM OFFICER.
BUT YOU CAN REACH OUT TO US.
WE WANT TO KNOW ABOUT THOSE
SITUATIONS AND DON'T WANT TO SEE
TALENT MOVING TO OTHER SECTORS.
>> NOT EVERYONE MAY HAVE BEEN
ABLE TO HEAR ALBERT AND
CHRISTINE WILL MENTION IT IN THE
MINUTES THE INITIATIVE YOU
POINTED OUT.
>> WE ARE HAVING A DISCREPANCY
IN THE PAY LINE.
IT'S A PIVOTAL MOMENT RIGHT
AFTER TENURE IN TERMS MUCH THE
SCIENTIFIC CAREER NOT HAVING THE
ABILITY MAKES A HUGE IMPACT IN
THE COMMUNITY.
AND IT'S IMPORTANT TO
UNDERSTAND BOTH THE FREQUENCY
AND INTENSITY.
SOME LOOK AT BIG GRANTS WITH
FREQUENCY AND GO FOR A WHILE
WITHOUT.
FROM THE FUNDING SIDE AS WELL AS
THE ACADEMIC SIDE AND PROMOTION
CASES NEED TO -- AND I KNOW OUR
INSTITUTIONS HAVE BEEN
REASSESSING AND IN PARTICULAR
OUR COMMUNITY WHICH OFTEN BUILDS
PARTNERSHIPS AND TEAMS AND
HELPING PEOPLE UNDERSTAND IT'S
NOT A SPRINT, IT'S A MARATHON
AND WANT TO LOOK AT THE
POTENTIAL FOR INDIVIDUALS TO
CONTRIBUTE OVER LONG PERIOD OF
TIME.
LET US KNOW.
>> I GUESS I WOULD LIKE SOME
COMMENT ON THE 24% PRODUCTION
FOR THE NON-CAREER STAGE
ADVOCATORS.
I HAVE FOUND MY OWN PROGRAM THAT
24% CUT REALLY HARD TO ABSORB.
10% THERE'S ROOM.
24% IS A QUARTER OF EVERYTHING
YOU PLANNED.
AND WHAT WERE THE THOUGHTS
BETWEEN A MORE GENEROUS PAY LINE
FOR YOUNG INVESTIGATORS AND
SHUTTING OFF WHAT SENIOR
INVESTIGATORS CAN DO WITH THE
BUDGET CUT?
>> I MAY HAVE DEFER THAT
QUESTION.
IT'S A BIG PICTURE
CONSIDERATION.
CONSIDERING IT'S NOT A GOOD ZIG
SITUATION TO BE IN.
BUT DRIVEN BY THE LIMITATION OF
THE ACTUAL AVAILABILITY OF
RESOURCES.
>> IT'S AN EXCELLENT POINT,
CYNTHIA WHEN DOES HARSH BECOME
TOO HARSH.
WE'RE ON TAR GUEST TO AWARD
COMPETING RO1s.
BUT WHEN DOES IT BECOME TOO
MUCH?
MAYBE IF WE GET A FLAT BUDGET
AGAIN OR INCREASED THAT WE'RE
USED TO, MAYBE WE HAVE TO MAKE A
SMALLER NUMBER OF RO1 AWARDS AND
LESS COST.
IT'S HARD TO ASSESS BECAUSE IT'S
NOT A NUMBER WE CAN ATTACH TO
BUT HEARING THIS IS HELPFUL TO
KNOW.
[OFF-MIC]
>> IT'S A QUARTER OF THE BUDGET,
ABSOLUTELY.
IT'S A CHALLENGING PERIOD.
WE'RE LOOKING LIKE IF THERE IS A
BUDGET ANOTHER FLAT ONE.
WE CERTAINLY DON'T KNOW THE
OUTCOME OF THAT -- THE EFFORT
THAT CAME FROM THE HOUSE WHICH
WE THINK IS GOING TO BE
DIFFICULT TO IMPLEMENTATION
PRACTICALLY.
TOO MANY MOVES IN TOO SHORT OF A
TIME.
IT SEEMS LIKE A LOT OF PEOPLE
PUT A LOT OF WORK INTO THAT AND
SOME OF THE POINTS THAT WERE
RAISED PERHAPS MAY CONTINUE TO
BE ISSUES THAT ARE PURSUED BY
POSSIBLY THE HOUSE AND POSSIBLY
BY OTHERS.
SO IT IS A REALLY WEIRD TIME.
WE JUST HAVE TO KEEP THIS
DISCUSSION GOING SO YOUR
FEEDBACK IS REALLY HELPFUL.
WE'RE ABOUT 35 MINUTES OVER AS
USUAL.
>> SO, YEAH, THANK YOU EVERYONE.
LET'S GO AN AUDIBLE ON THE BREAK AND WE'LL TAKE OUR BREAK NOW AND
LET'S ATTEMPT TO RECONVENE AT 11:30. THANK YOU VERY MUCH.
WITH THE PRESENTATION OF
DIRECTOR OF DIVISION OF
INTERDISCIPLINARY TRAINING AND
ON RE-ENVISIONING POSTDOCTORAL
EXPERIENCE AND WE HAD QUESTIONS
FROM COUNCIL MEMBERS AND NOW
ZEYNEP AND THE TEAM ARE CARRYING
THIS FORWARD.
THANK YOU.
>> THANK YOU, DAVID.
GOOD MORNING, EVERYONE.
THE TOPIC OF MY TALK TODAY IS
POSTDOCTORAL EXPERIENCE IN
BIOMEDICAL IMAGINING AND
BIOENGINEERING.
I'M GOING TO START BY SAYING
I'LL USE THE TERMINOLOGY BIB TO
REFER TO ALL THE FIELD FROM
ENGINEERING, PHYSICAL SCIENCES
AND COMPUTATIONAL SCIENCES.
IN OUR NAME, NIBIB WHEN I REFER
TO IT WILL MEAN BIO MEDICAL
IMAGING AND BIO ENGINEERING.
AND I WANT TO SAY AT THE RISK OF
DISAPPOINTING SOME PEOPLE THAT
I'M NOT HERE TO PROVIDE A
COMPLETE OVERVIEW OF THE
POSTDOCTORAL EXPERIENCE IN BIB.
THE PURPOSE OF MY TALK IS TO
START THE CONVERSATION AND FRAME
IT AND HOPEFULLY ENCOURAGE
PARTICIPATION IN THE TOPIC.
IN RECENT YEARS THERE'S BEEN
CONSIDERATION OF THE
EFFECTIVENESS AND NOT CLEAR THE
SYSTEM OPTIMALLY PREPARED A
COMPETENT AND DIVERSE WORKFORCE
TO SUPPORT THE BIOMEDICAL
RESEARCH ENTERPRISE NIH
ENVISIONS.
THERE'S FURTHER CONCERN IN HOW
IT SERVES THE SCHOLARS AND THEIR
PROGRESS.
-- PROGRESSION AND UNCERTAIN
PROSPECTS OF SECURING FACULTY
POSITIONS AT THE END OF THE
POSTDOC ARE JUST A FEW AMONG THE
FACTORS THAT DIMINISH THE APPEAL
OF POSTDOCTORAL POSITIONS.
TO COVID-19 PANDEMIC AND THE
ECONOMIC CONSEQUENCES FURTHER
EXACERBATE THE CHALLENGES.
DATA ON DECLINING POSTDOC
NUMBERS SUGGEST THE SHORTAGE LED
TO CONCERNS ABOUT IMPLICATIONS
FOR THE FUTURE OF THE
U.S. BIOMEDICAL RESEARCH
ENTERPRISE.
NIH SOUGHT TO EVALUATE THE
STATUS OF THE TRAINING PROCESS
UNDERSTAND FUNDAMENTAL ISSUES
AFFECTING SCHOLARS AND ADDRESS
THE ISSUES.
TO THIS END THE NIH ADVISORY
COMMITTEE TO THE DIRECTOR WE
REFERRED TO AS ACB PRODUCED THE
REPORT WITH SEVERAL
RECOMMENDATIONS I'LL GO INTO IN
A FEW SECONDS.
AT NIBIB OUR INTERNAL DATA
DEMONSTRATE THE THE DECLINE IN
POVERTY POSTDOCS.
WE HEARD YOU ARE HAVING TROUBLE
RECRUITING POSTDOCS, FILLING
POSTDOC POSITIONS AND STAFFING
IN LABS.
KEEPING IN MIND THE DIFFERENT
FACTORS THAT MAY BE AT PLAY IN
THE TECHNOLOGY DEVELOPMENT SPACE
WE WISH TO FIRST ASSESS IF
THERE'S A PROBLEM WITH THE
POSTDOCS THAT CALL FOR
INTERVENTION.
IF IT'S DETERMINED THE DECLINE
POSTDOCS IS A PROBLEM WE WISH TO
ADDRESS WHETHER THE NIH WORKING
GROUP RECOMMENDATIONS ARE
SUFFICIENT FOR THE COMMUNITY OR
WHETHER WE NEED CUSTOMIZED
INTERVENTIONS THAT TAKE INTO
ACCOUNT AND TO BENEFIT FROM YOUR
INSPUT AND PERSPECTIVE WE'RE
CONSIDERING ESTABLISHING THE
WORKING GROUP.
SO TODAY I'M GOING TO START BY
PROVIDING A BACKGROUND AND
INFORMATION ON THE NIH EFFORTS
SO FAR.
I WILL DISCUSS SOME SPECIFIC
CASES FOR NIBIB'S WORKFORCE AND
INTRODUCE A WORKING GROUP THAT
WE ARE CONSIDERING FORMING TO
EVALUATE THE POTENTIAL PROBLEM
IN THE CONTEXT OF NIBIB
WORKFORCE, GAIN A BETTER
UNDERSTANDING, MAKE
RECOMMENDATIONS FOR NIBIB AND
NIH AND ALSO PERHAPS REACHING
BEYOND NIBIB AND NIH.
SO IT SHOWS POSTDOC LEVELS OVER
THE YEARS.
IT IS A LITTLE BIT COMPLICATED
TO INTERPRET THIS BECAUSE OF THE
AESTHETICS DEMONSTRATING A
CHANGE IN THE WAY THE DATA WAS
COLLECTED IN THOSE YEARS OR
START BEING IN THOSE YEARS.
IT'S CLEAR THAT THE STEADY RISE
THAT HAD BEEN TAKING PLACE HAS
LEVELED OFF AND IN THE FINAL
PART OF THE PLOT FROM '20 TO '21
THERE'S A 7.6% DECREASE IN
POSTDOCTORAL SCHOLARS.
THE PLOT ALSO SHOWS THE
NON-FACULTY RESEARCHERS WITH
DOCTORS.
THOSE ARE INDIVIDUALS THAT HAVE
Ph.D.s BUT THEY ARE NOT IN
POSTDOCTORAL POSITIONS NOR DO
THEY HAVE A FACULTY POSITION.
THE PLOT SHOWS A CON STAVENT
BEHAVIOR IN THOSE INDIVIDUALS IN
THE LAST YEARS.
THE PLOT ON THE RIGHT-HAND SIDE
HAS DATA SPECIFICALLY FROM NIH
AND SPECIFICALLY SUPPORTED
POSTDOCTORAL SCHOLARS.
THE NSRA HAS TWO MEANS OF
SUPPORTING POSTDOCTORAL
SCHOLARS.
ONE ARE THE TRAINING GRANTS
AWARDED TO INSTITUTIONS AND
SUPPORT MULTIPLE INDIVIDUALS AND
AS PLOTTED WITH THE GREEN PLOT
AND RED PLOT SHOWS THE OTHER
MECHANISM THAT SUPPORTS THE
POSTDOCS WHICH ARE FELLOWSHIPED
DIRECTLY AWARDED TO POSTDOCS
THEMSELVES.
AS YOU CAN SEE THERE'S A
CONTINUOUS DECLINE ESPECIALLY IN
THE LAST YEARS IN BOTH
MECHANISMS OF SUPPORT.
AND TO ENVISION THE POSTDOCTORAL
EXPERIENCE, NIH FORMED AS I SAID
THE ACD WORKING GROUP.
THAT WAS AT THE END OF DECEMBER
AT THE END OF 2022 AND THEN THE
COMMITTEE MET CONTINUOUSLY
THROUGHOUT '23 AND AT THE END OF
'23 PRODUCED RECOMMENDATIONS.
IS THE COMMITTEE CONSIDERED
SURVEYS CONDUCTED BY SES AND BY
NATURE AND ONE SURVEY CONDUCTED
BY THE POSTDOCTORAL ASSOCIATION.
AND IN REPRESENTATIONS TO THE
RFI AND TO RETAIN POSTDOCTORAL
SCHOLARS.
THE MAIN RECOMMENDATIONS OF THE
WORKING GROUP WAS TO INCREASE
PAIN BENEFITS FOR POSTDOCTORAL
SCHOLARS.
MECHANISMS TO EXPORT THE FULL
TALENT OF POSTDOCTORAL SCHOLARS,
FACILITATE THE TRANSITION OF
POSTDOCTORAL SCHOLARS INTO THEIR
NEXT CAREER STAGE INCLUDING
ROLES IN ACADEMIC FACULTY.
PROMOTE PROFESSIONAL DEVELOPMENT
OF POSTDOCTORAL FELLOWS AND
THEIR MENTORS AND PERSPECTIVES
AND ENVIRONMENTS WITHIN RESEARCH
PROGRAMS AND IMPROVE MEANS TO
MEASURE AND SHARE POSTDOCTORAL
SCHOLARS CAREER PROGRESSION.
NIH HAS STARTED IMPLEMENTING
SOME OF THE RECOMMENDATIONS.
MOST NOTABLY THE STIPEND IN RSA
AWARDS HAVE BEEN INCREASED.
ALSO THE APPLICATION AND REVIEW
PROCESS FOR THE FELLOWSHIPS HAVE
BEEN NOTIFIED SO THE FULL
POSTDOCTORAL FELLOWS RECEIVE
CONSIDERATION.
THIS IS FOR FOLLOW-UP REQUEST
FOR RECOMMENDATIONS AND IT
SPECIFICALLY FOCUSES ON HOW TO
BEST IMPLEMENT SOME OF THE
SPECIFIC RECOMMENDATIONS THAT
THE ACD PROPOSED.
THESE ARE LIMITING THE NUMBER OF
YEARS A PERSON CAN BE SUPPORTED
BY NIH FUNDS IN A POSTDOCTORAL
POSITION TO FIVE YEARS AND THIS
INCLUDES SUPPORT NOT ONLY ON
NRSAs.
REVIVING THE K99, R00 MECHANISM
ON CREATIVITY AND SHORTEN THE
ELIGIBILITY WINDOW TO TWO YEARS.
PROMOTE TRAINING AND
PROFESSIONAL DEVELOPMENT OF
POSTDOCS.
INCLUDING MENTORS AND ENSURE
EQUITABLE ACCESS.
I WANT TO HIGHLIGHT THE LINE'S
COMING UP IN OCTOBER '23.
WE ENCOURAGE YOU TO GO TO THE
LINK AND PROVIDE YOUR FEEDBACK
FROM THE NIBIB COMMUNITY.
THESE RECOMMENDATIONS THE ACD
WORKING GROUP CAME UP WITH ARE
DEFINITELY MOVING THINGS IN THE
GENERAL DIRECTION FOR THE NIH
BUT UNDERSTAND THE DIFFERENCE
BETWEEN OUR COMMUNITY AND THE
REST OF THE NIH.
THERE'S CERTAIN FACTORS AT PLAY
THAT MAY CALL FOR MORE
CUSTOMIZED SOLUTIONS THAN WHAT
NIH, ACD WORKING GROUP CAME UP
WITH.
SOME OF THESE DIFFERENCES COULD
BE THE NIBIB COMMUNITY COULD
FIND MORE OPPORTUNITIES AND
HIGHER SALARIES IN THE PRIVATE
SECTOR THAN THOSE IN BIO MEDICAL
SCIENCES AT THE NIH AND
POSTDOCTORAL EXPERIENCE MAY NOT
BE AS REQUIRED OR EVEN VALUED IN
THE NIBIB SPACE AS IN BIO
MEDICAL AND BIOLOGICAL STUDENTS
AND POSTDOCS MAY HAVE
CHALLENGES.
WHEN WE LOOK AT BIO ENGINEERING
WE SEE FROM THE SES DATA THE
SURVEYS THAT THE POSTDOCTORAL
APPOINTEES IN THE GENERAL SPACE
ARE DECREASING.
THE PLOTS ON THE LEFT-HAND SIDE
INCLUDE GENERAL SCIENCE,
BIOMEDICAL SCIENCES AND I'M
SORRY THE LEGEND HERE IS CUT OFF
A LITTLE BIT.
AND WHEN WE NORMALIZE VALUES TO
2018 WE SEE IN BIOLOGICAL AND
BIOMEDICAL SCIENCES WHICH IS THE
ORANGE LINE HAS FLATTENING TO
2020 AND DECREASE WHEREAS INNIO
ENGINEERING THERE'S AN INCREASE
IN 2020 AND THEN A SHARP
INCREASE THAT IS PARALLEL TO
THAT OBSERVED IN THE BIOLOGICAL
AND BIOMEDICAL SCIENCES.
WHEN WE LOOK AT OUR DATA FROM
OUR POSTDOCS WE SEE A DECLINE IN
POSTDOCS HERE AS WELL.
AND THEY'RE SUPPORTED AT 32,
K99s AND T32s AND THE PURPLE ARE
POSTDOCS IN RPGs AND THE
POSTDOCS ON RP
RPGs ARE ROUGH ESTIMATES.
THE POSTDOCS THAT ARE THE BARS
ARE ABOVE THE QUARTER OF PAY
BEGINNING VALUE.
THE DECLINE IN THE POSTDOCS
CAN'T BE EXPLAINED BY DECREASED
IN BUDGET CUTS.
THEY'RE DOMINATED BY THE SUPPORT
POSTDOCS RPGs ON PROJECT GRANTS.
ONE REASON COULD BE A LACK TO
Ph.D. STUDENTS IN THE PIPELINE.
WE LOOKED AT DATA LINE WHEN WE
NORMALIZE TO BEGINNING VALUES,
WE SEE PRACTICALLY ALL THE
DISCIPLINES ARE DECREASING THE
POSTDOCTORAL STUDENT ENROLLMENT
AND THE BIO ENGINEERING GROUP
HAS THE SHARPEST INCREASE.
SO, KEEPING OUR FOCUS ON THE BIB
COMMUNITY WE'RE RAISING THE
QUESTION WHETHER THE ACD
RECOMMENDATIONS WILL BE
APPLICABLE TO OUR COMMUNITY AND
SUFFICIENT.
SOME OF THE RECOMMENDATIONS LIKE
SALARY INCREASES AND SUPPORTING
SAFE AND DIVERSE PERSPECTIVES
AND AS A WHOLE DO THE
RECOMMENDATIONS REALLY APPLY TO
OUR COMMUNITY AND ARE THEY
SUFFICIENT?
FIRST OF ALL WE NEED TO
INFORMATION WHETHER THE LACK OF
POSTDOCS IS EVEN A PROBLEM.
MAYBE FOR OUR COMMUNITY POST DOC
ISN'T A NECESSARY PHASE AND
MAYBE IT'S OUTLIVED IT'S
USEFULNESS AND MAYBE THERE'S TOO
MANY POSTDOCS BEING PREPARED OR
SOME OF THE RECOMMENDATIONS THE
SPECIFIC RECOMMENDATIONS MIGHT
GET DECREASE THE YEARS OF
ELIGIBILITY FOR OF K99s.
MAYBE WE DON'T WANT IT DECREASED
THAT MUCH MORE ENGINEERING OR
DECREASE IT EVEN MORE.
AND MAYBE THERE ARE SOME
COMPLETELY DIFFERENT
INTERVENTIONS THAT COULD BE
NECESSARY OR COULD BE USEFUL AND
MORE COLLABORATIONS WITH THE
PRIVATE SECTOR.
SO WE ARE PLANNING TO START THIS
WORKING GROUP SO THAT WE GET
YOUR EXPERIENCE AND PERSPECTIVES
TO ASSESS A, IF THERE'S A
PROBLEM, IF SO, UNDERSTAND THE
FACTORS DRIVING IT AND DEVELOP
INTERVENTIONS TO OVERCOME IT.
SO THE CHARGE TO THE WORKING
GROUP IS TO EVALUATE EVIDENCE ON
SHORT AND ON U.S. POSTDOCS IN
BIO ENGINEERING AND BIO IMAGING
AND UNDERSTAND DRIVERS FOR THE
BIB COMMUNITY AND WHAT MEASURES
WE SHOULD TAKE IN ADDITION TO
THE ACD RECOMMENDATIONS AND
CREATE AN IMPACTFUL PLAN FOR
RESTRUCTURING THE ENTERPRISE
NIBIB IN GOVERNMENT AGENCIES.
WE HOPE YOU'RE INTERESTED AND
WILLING TO WORK WITH US IN THE
WORKING GROUP AND CYNTHIA WAS
RECOMMENDING TO EAVESDROP AND IN
INCORPORATE YOUR PERSPECTIVES
AND INSIGHT INTO OUR PROGRAM
DEVELOPMENT.
SO IF YOU ARE INTERESTED PLEASE
CONTACT ME AND WILLING TO
PARTICIPATE AND WE APPRECIATE A
RESPONSE BY THE 24th IF
POSSIBLE.
I WILL STOP HERE AND TAKE ANY
QUESTIONS.
I'LL TAKE COMMENTS AND
SUGGESTIONS.
>> I HAVE A QUESTION.
ARE YOU GOING TO LOOK AT WHETHER
THE PEOPLE WHO WOULD HAVE BEEN
POSTDOCS WHO WEREN'T POSTDOCS
HAD BETTER CAREERS OR MORE
PRODUCTIVE CAREERS THAN PEOPLE
WHO DID?
LIBE YOU SAID, AND WHEN I WAS AN
UNDERGRADUATE TUNE MANY DECADES
AGO NOBODY IN ENGINEERING DID
POSTDOCS.
SO THERE WERE JUST JOBS
AVAILABLE, POSTDOCS WERE ONLY IN
THE OTHER FIELD OF SCIENCE.
IT WOULD BE A MEASURE OF OTHER
OPPORTUNITIES AND THE QUESTION
BECOMES WELL, IS THE POSTDOCs
CAREER BETTER OFF IF THEY HAD
DONE A POSTDOC OR NOT.
WE HOPE YOU JOIN THE WORKING
GROUP AND --
>> I GUESS THE QUESTION THAT
OCCURS TO ME AND YOU GESTURED AT
THIS ONE OF THE KEY PROBLEMS
THAT THE HIP PANEL AND WHAT
WHAT'S THE FEAR WE'RE LOSING
FUTURE SCIENTISTS OR WE'RE NOT
SUFFICIENTLY FUNDING FUTURE
SCIENTISTS THE POSTDOC
EXPERIENCE IS AWFUL AND EVERYONE
RUNS SCREAMING?
WHAT'S THE DECLINE?
>> I BELIEVE THE FEAR IS HOW IS
THE SHORTAGE OF POSTDOCS GOING
TO EFFECT THE BIOMEDICAL
RESEARCH ENTERPRISE AS A WHOLE
IN THE FUTURE.
>> WE'RE HAVING TROUBLE HIRING
COMPLETELY.
SO WHEN YOU PLAN AND WHEN YOU
CAN'T FIND POSTDOCS YOU HAVE
OVER COMMITTED CARRY FORWARD AND
YOU'RE OVER 25% AND THE ANSWERS
ARE CONTINUING WE CAN'T.
>> I FOUND THAT AS WELL TO BE
SURE.
ARE THERE MORE AND MORE PEOPLE
WHO WOULD HAVE GONE INTO BIO
MEDICAL INSTEAD GOING TO A.I.
AND START-UPS?
OUR IMAGING SOCIETY WE'VE FOUND
THAT IF YOU ALONG AT THE NUMBER
OF PEOPLE LOOK FOR JOBS AND
THERE'S JOB MATCHES SOCIETY'S
PUT TOGETHER, THE NUMBER OF
PEOPLE LOOKING FOR INDUSTRY JOBS
HAS SWUNG CRAZILY AND NOW
DRASTICALLY I THINK OUT NUMBERS
THE NUMBER OF PEOPLE LOOKING FOR
ACADEMIC JOBS.
THIS COULD BE A BIG SOCIETAL
TREND AS WELL AS AN NIH TREND.
Z
>> CREATE BE A RESEARCH FACULTY
TRACK AND SUCCESS THERE MAY
FACILITATE A SUCCESSFUL CAREER
MOVING FORWARD.
WE'RE DISCUSSING THE INTRACTABLE
OF TENURED POSITION AND
DIFFERENT FOLLOW ON PATHWAY IS
SOMETHING TO CONSIDER.
>> AND HAVE A WELL INFORMED
TRAJECTORY AND GOING DOWN THE
PATH I HAVE NO IDEA WHERE IT'S
GOING TO LEAD ME.
>> THERE'S BIO ENGINEERING
CREATING OPPORTUNITIES FOR
GRADUATE PROGRAMS THEY'RE
STRONGLY THERE.
WE GET SUBSCRIPTIONS FROM
NON-ENGINEERING DISCIPLINES WHO
REALLY WANT TO HAVE INDUSTRY
SPACE.
THERE'S THAT AND INDUSTRY'S
DOING WELL AND I THINK HAVING
COMPETITION FROM PRIVATE IS A
GOOD FORCE THERE.
THE ORDINANCE IS YOU MENTIONED
THERE'S A NEED.
AND THE NEED IS MAKING SURE WE
HAVE A GOOD PIPELINE OF VERY
ABLE FOR CAREER AND WE TALK TO
STUDENTS AND ONE STUDENT WENT TO
ACADEMIA.
>> TO REITERATE I THINK A
QUESTION MIGHT BE IS THERE A
FOCUS ON THE ACADEMIC SIDE AND
MAKING SURE THERE'S ONE PEOPLE
TO FILL THE POSITIONS AND DO THE
RESEARCH AND THINKING ABOUT THE
DICHOTOMOUS PARTS BECAUSE
THEY'RE NOT ALWAYS CONNECTED IS
IMPORTANT.
>> IN CONNECTING WITH INDUSTRY
MAYBE IT'S AWAY OF TURNING A
PROBLEM INTO AN ADVANTAGE.
THERE WOULD HAVE BEEN PEOPLE IN
THE POSTDOCS INTERESTED IN
INDUSTRY MAYBE THEY CAN BE THE
CONNECT POINTS BETWEEN ACADEMIA
AND NIBIB AND INDUSTRY THAT
COULD REALLY HELP SPIN THINGS UP
AS WELL.
SO THAT COULD BE PART OF THE
STRATEGY ALMOST.
>> I THINK WHAT WE'RE TRYING TO
ZERO IN IS ABOUT WHAT YOU AS THE
COMMUNITY WOULD LIKE TO SEE.
WE'RE DIFFERENT FROM THE REST OF
NIH IN THE SENSE WE HAVE SO MANY
DIFFERENT SYNCS OUR POSTDOCS CAN
GO TO AND WHAT DO WE NEED TO
THINK ABOUT IN MEETING NEEDS YOU
GET ACADEMIC CREDIT FOR GRAD
STUDENTS BUT MAYBE NOT SO MUCH
FOR POSTDOCS.
OTHERS PARTICULARLY THOSE IN MED
SCHOOLS NEED TO GET POSTDOCS OR
BE JOINTLY APPOINTED IN
NINE-MONTH ACADEMIC PROGRAMS TO
HAVE ACCESS TO STUDENTS.
IT'S MULTIPLE PROBLEMS TOGETHER
BUT THE BOTTOM LINE FROM OUR
PERSPECTIVE IS WE KNOW THAT OUR
COMMUNITY IS DIFFERENT FROM THE
REST OF NIH.
WHAT CAN WE TRY TO CONCEIVE OF
IN ORDER TO MEET THE NEEDS OF
YOUR TRAINING PROGRAMS SO YOU
HAVE IT MOVING FORWARD AND CAN
WE GET A BIGGER PICTURE VIEW OF
ACADEMIC GROWTH.
MANY SAW THE HEYDAY WHERE
DEPARTMENTS WERE FORMING LIKE
ONCE A WEEK AND I HAD A NUMBER
OF FACULTY HIRES PER MONTH AND
YEAR AND THERE WERE SO MANY.
FROM A PHOTONICS POINT OF VIEW
AND SOME THOUGHT I LIKE IT IT'S
GOOD AND SUDDENLY IT'S AROUND
THE PROGRAMS IN THE COUNTRY.
THE QUESTION IS WHAT ARE THE
FUTURE TRENDS OR PEOPLE MY AGE
AND OTHERS AROUND THE ROOM ARE
WE GOING TO RETIRE IN WAVES AND
YOU GUYS HAVE SEEN AS WELL
BIOLOGY DEPARTMENTS HIRING.
AND TRADITIONAL ENGINEER IING A
HOW WE'RE SUPPLYING AND TRAINING
AND SUPPLIES.
AND MORE OF A FRAMEING THIS.
>> AND HAVE SENIOR GRADUATE
STUDENTS BEEN SURVEYED?
AND THERE'S AN EFFORT IN
SCIENTIFIC SOCIETY OR WHAT THEIR
NEEDS OR CHOICES AND HOW THEY
DECIDE.
ANECDOTALLY WITH YOUR STUDENTS
I'VE NOTICED A TREND AND ALWAYS
ASK STUDENTS WHETHER THEY'RE
COMING IN AS A NEW GRADUATE
STUDENT ARE YOU INTERESTED IN
ACADEMIA, INDUSTRY AND PRE
PREDOMINATELY THERE'S A BIG
SHIFT ALMOST ALWAYS INDUSTRY.
I KNOW YOU HAVE THE DATA FROM
NSF WHAT ARE THE NUMBERS MUCH
GRADUATE STUDENTS BUT THEN WHERE
THAT'S BE DONE AND I KNOW
THERE'S POSTDOC ORGANIZATIONS
AND YOU MENTIONED CLIMATE, EVEN
LITTLE THINGS LIKE CHILDCARE
SOME CAN'T BE A POVERSTDOC.
I CAN'T LIVE ON THAT SALARY.
THOSE ARE REAL ISSUES.
NIH HAS HAD POSTDOC GROUPS WITH
THEIR VOICE HAS BEEN HEARD AND
WONDER WHERE THEIR VOICE IS IN
THIS?
YOU'RE SUGGESTING A DIFFERENT
VFSH.
>> THERE MAYBE A FLATTENING OR
DECLINE AND RIGHT SIZING WHAT
WE'RE DOING AT THESE LEVELS IS
GOING TO BE IMPORTANT BECAUSE
OTHERWISE WE'RE GOING TO TRAIN A
COHORT OF INDIVIDUALS THAT DON'T
HAVE THE APPROPRIATE -- TRYING
TO I WOULD SAY IF YOU CAN GET
MORE DATA IN TERMS OF GROWTH IN
FACULTY AND BUDGETS WHICH I
THINK THE PEER STUDENT-ATHLETES
ARE TRYING TO AMAT THAT COULD BE
HELPFUL.
AND IN THE SINGLE DIGIT
PERCENTAGES IS DIFFERENT THAN
WHAT WE SAW IN THE BIOMEDICAL
ENGINEERING BOOM.
>> THAT COMES BACK TO
ALTERNATIVE PATHWAYS FOR
POSTDOCS AND GET VISIBILITY FOR
THOSE AS WELL.
THINKING WITH ACADEMIA AND THE
VAST MAJORITY IT'S HARD TO
RECRUIT MOST POSTDOCS AND A VAST
MAJORITY OF APPLICATIONS COME
FROM OUTSIDE THE UNITED STATES.
I THINK WE HAVE A PARTICULAR
PROBLEM WITH U.S. TRAINED Ph.D.s
NOT WANTING TO DO POSTDOCS AND
WE NEED TO UNDERSTAND WHY.
THE NEED IS THERE.
WE ALSO NEED MORE POVERTY --
POSTDOCS IN THE RIGHT POSITIONS
IS WE NEED TO FIND OTHER
PATHWAYS.
>> WE THESE TO LOOK AT IT BEING
PART OF A PROGRAM LIKE A
RESIDENCY COMBINATION AND YOU
KNOW WHAT'S AT THE END OF IT.
THEY HAVE SOME CERTAINTY.
THAT'S WORKED FOR ME WELL WHEN
THE Ph.D.s WANT TO GET CLINICAL
POSITION AND DON'T WANT TO GIVE
UP THE RESEARCH RIGHT AWAY AND
WANT TO HAVE RESEARCH IN THEIR
CLINICAL POSITION.
FOR THEM AND YOU HAVE TO HAVE
STAKEHOLDERS TO HIGHER THE
POSTDOCS IN THE SUBMISSION.
>>
>> THE NEXT AT MICHIGAN LAST
WEEK AND PEOPLE WITH WANT TO
BECOME PROFESSORS FOR
ENGINEERING AN TALKING WHY THEY
WERE AROUND THE FENCE AND ONE
THING TO CONSIDER AND WHEN GOING
THROUGH MY POSTDOC IS THE OTHER
ENGINEERING DISCIPLINES WERE
DOING ELECTED ELECTRICAL AND
THERE'S ANOTHER QUESTION OR
QUERY IS HOW DOES IT COMPARE IF
THERE'S A MECHANICAL ENGINEER
GRAD STUDENTS AND IT'S MORE
HARDCORE FOR COMPUTER
ENGINEERING TO APPLY TO BIO BUT
WOULD NOT SEE IT AS NECESSARY
FOR THEIR FIELD BUT I FEEL
THERE'S MORE HYBRID.
WHY A POSTDOC WOULD BE HELPFUL
AND SOME SAY THEY'D NEVER DO A
POSTDOC.
>> A LOT DEPENDS ON THE
INSTITUTION THEY'RE COMING FROM
AND THEIR RESEARCH IN BIOMEDICAL
ENGINEERING NOW YOU CAN'T LEAVE
THE PROGRAM WITHOUT KNOWING
SOMETHING IMPORTANT ABOUT
BIOLOGY AND YOU ALSO GET EXPOSED
TO DIFFERENT CAREER PATHS SO
COMMERCIALIZATION,
ENTREPRENEURSHIP, INNOVATION.
THOSE TEND TO BE EMBEDDED IN OUR
CURRICULUM.
LIKE EVERYONE KNOWS IN AN
UNDERGRADUATE TIME WHAT A 5, 10K
WAS.
THAT WASN'T THE CASE 10, 15
YEARS AGO.
THE TRAINING PROGRAM'S
DEPARTMENTS AND I DON'T KNOW WHO
WE WORK THROUGH, DEPARTMENT
CHAIRS OR DEANS, COUNCIL OF
DEANS, IT SEEMS LIKE WE MIGHT
NEED TO COORDINATE TO GET MORE
INFORMATION WHERE THE STUDENTS
WERE GOING AND ABOUT THE
UNIVERSITY.
IT'S THE QUESTION OF WHERE IS
THE PUCK GOING FOR THE
UNIVERSITIES AND HOW CAN WE BE
RESPONSIVE RECOGNIZING WE CAN'T
MEET ALL THE NEEDS AT THE SCALE
BUT WE CAN INSPIRE OUR
COLLEAGUES WHO HAVE THE BIG
MONEY BECAUSE A LOT OF THE
POSTDOCS ARE BEING SUPPORTED BY
NHLBI AND NCI.
OTHER INSTITUTES HAVE THE
RESOURCES.
SO WE WANT TO -- LIKE WE USUALLY
DO, CREATE SOME INNOVATION AND
GET IT GOING AND TRY TO GET IT
TO SPREAD TO OTHER INSTITUTES
AND CENTERS.
>> UNMY EXPERIENCE MANY POSTDOCS
ARE ON THE FOREFRONT OF
INNOVATION AND MANY MECHANISMS
FOR STARTING COMPANIES AND
EARLIER STAGE OR FACULTY STAGE
AND THERE MAY BE AN OPPORTUNITY
TO HAVE POSTDOCS THAT BUILD IN
SO THE INNOVATION ECO SYSTEM AS
WELL BECAUSE I JUST FEEL LIKE
THAT'S A MISSING PIECE.
THERE'S INDUSTRY, ACADEMIA BUT
REALLY THESE ARE THE PEOPLE WHO
ARE PUSHING TECHNOLOGY FORWARD
IN THE LAB.
>> ONE THING I STARTED DOING IN
MY LAB IS HIRING A MID TIER
LEVEL OF SCIENTISTS A POSITION
THAT MAY HAVE POSTDOCS AND NOT
EVERYONE BE A PERMANENT MEMBER
OF THE LAB BUT DON'T WANT TO
EVOLVE INTO A LAB DIRECTOR.
THEY'RE HAPPY TO BE A LAB TEAM
MEMBER FOR THEIR LONG-TERM
CAREER.
AND THAT IN SOME WAYS WAS SEEN
AS FAILURE.
YOU HAVE TO GO ON AND SEE A PI
AND SO THE DON'T WANT THE
RESPONSIBILITIES THAT ARE GOOD
TIER SCIENTIST LEVEL.
>> IT'S INTERESTING THE SOFTWARE
ENGINEER PROPOSALS WE'RE SEEING
ARE SEEING A NARROWER SECTOR OF
A RESEARCHER CONTRIBUTE TOCK TO
THE LAB NOT NECESSARILY THE P.I.
AND DRIVING PROPOSALS.
I DON'T KNOW IF ACROSS NIH IT
WILL EMERGE AS FUNDING
OPPORTUNITIES.
USUALLY ACADEMICS COMPARED TO
INDUSTRY HAS A DIFFERENT PAY
SCALE FOR THAT SERIES AND THAT
HITS OUR COMMUNITY PRETTY HARD
IN TERMS OF MAKING CHOICES.
>> THERE'S ONE THING I HAVEN'T
HEARD WHICH IS IN THE INTRAMURAL
PROGRAM THE DISCUSSION ABOUT
POSTDOCS IS CENTERED ON THE FACT
THEY'RE UNIONIZED NOW AND THE
SALARIES HAVE GONE UP
SIGNIFICANTLY IN THE LAST
SEVERAL YEARS AND IT'S A
QUESTION OF NOT WHETHER WE CAN'T
FIND THEM BUT A QUESTION OF WITH
FLAT BUDGETS WE SIMPLY CAN'T
AFFORD THEM.
I DON'T KNOW IF WHETHER PERHAPS
I THINK WE'RE IN A DIFFERENT
SITUATION BUT WANTED TO RAISE
THE SITUATION OF THE INCREASE IN
SALARIES MAY EQUITY IN SOME
AREAS FOR THE DECREASE.
>> DO YOU GUYS HAVE EXPERIENCE
WITH THAT?
THERE'S THE U.S. SYSTEM AND NOT
TO SHIFT TOO MUCH BUT THERE'S
UNIONIZATION AT THE GRAD STUDENT
LEVEL SOMETHING WE'RE CURRENTLY
CONSIDERING HOW DO WE DEAL WITH
THAT AND THERE'S A COMMENSURATE
SALARY INCREASE THERE THAT WILL
HIT GRANTS WITH FINITE CAPS AND
FIGURING OUT HOW TO DEAL WITH
THAT IS SOMETHING WE'RE
GRAPPLING WITH.
>> I THINK THAT'S WHY STLGSS ARE
BEING MORE CONSERVATIVE.
-- INSTITUTIONS ARE BEING MORE
CONSERVATIVE WE'RE HAVING TO
FILL GAPS AT ALL LEVELED.
REALLY BEING COGNIZANT OF THE
UNIONIZATION WILL BE IMPORTANT.
>> THIS IS GETTING TOPIC OUT FOR
DISCUSSION AND PEOPLE ARE
STARTING TO CONTEMPLATE THESE
ISSUES.
THESE ARE ISSUES WE'VE ALL BEEN
THINKING ABOUT.
WE NEED TO PROBABLY GET THE
IDEATION GOING AND DRAW IN OTHER
AUTHORI
AUTHORITIES AND DEAN GROUPS AND
ACCESS THEM TO GET THEIR
DIALOGUE GOING.
THERE ISN'T IN THE NEAR TERM
MORE MONEY IN THE ACADEMIC
SYSTEMS.
MANY SYSTEMS ARE STILL REELING
FROM THE PANDEMIC EXPENDITURES
AND I THINK THERE WAS JUST AN
UPTICK IN ENROLLMENT THE PAST
YEAR.
THERE'S ALSO BEEN A DOWN TURN IN
INTERNATIONAL STUDENTS AND FROM
MY KNOWLEDGE APT THE U.C. SYSTEM
AND THAT REALLY DROVE A LOT OF
EXPANSION IN PROGRAMS.
AND THEY'RE CONTRIBUTING TO
ECONOMIC GROWTH AND EXPANSION
AND DRIVING THE CENTERS FOR
INNOVATION AND ACCELERATORS
AROUND THE COUNTRY AND I THINK
MANY ACADEMIC CENTERS ARE
RECOGNIZING THE VALUE OF
RETAINING TALENTED PEOPLE WITHIN
A 50-MILE RAID UGHS -- RADIUS
AND THE INSTITUTION AND SILICON
VALLEY AND OTHER EXAMPLES AND
BUILDING UP AN ENTREPRENEURIAL
ENTERPRISE WHERE PEOPLE CAN
EASILY MOVE FROM SAY ONE ENTITY
TO ANOTHER BECAUSE THE NATURE OF
THEM THEY START AND DISAPPEAR
AND WHEN THEY DISAPPEAR YOU HAVE
TO MOVE 3,000 MILES AWAY.
YOU CAN GET A JOB LIKE WITHIN
FIVE OR 10 MILES.
THAT'S THE GOAL.
HOW DO WE CONTRIBUTE TO THAT ECO
SYSTEM.
DO WE NEED TO SHIFT FUNDING TO
ANOTHER DEFINED -- DO WE NEED TO
CREATE CHANNELS SO THERE'S OTHER
DEFINED POSITIONS IN BETWEEN?
HOW DO WE CONTINUE TO ENSURE AND
DEDICATE LIKE MY FEELING AND
PROBABLY A LOT OF YOU, POSTDOCS
REALLY LEARN HOW TO WRITE GRANT
PROPOSALS.
IF NEURO NOT SKUCCESSFUL AT THA
YOU WON'T BE SUCCESSFUL IN
ACADEMIA IN THE LONG-TERM RUN.
THAT'S TELL IT LIKE IT IS HERE
FOR THOSE PEOPLE AND OTHER
THINGS TAILORED FOR OTHER PEOPLE
AND DIFFERENT CAREER PATHS.
I KNOW IT'S A BIG ASK.
IN A SENSE IT'S AN OPEN QUESTION
AND A DIALOGUE FOR US TO GET
GOING AND POSSIBLY SEE WITH
OTHER COLLEAGUES.
>> ONE OF THE BIG QUESTIONS
SENATOR SANDERS IS HOW TO GET
DRUG PRICES DOWN OR JUST THE
COST OF HEALTH CARE DOWN.
WE'RE ALWAYS GOING TO BE CAPPED
BY THE AMOUNT OF MONEY THAT'S
APPROPRIATED BY CONGRESS.
IF YOU EDUCATE THEM AND SAY
LISTEN, IF YOU'RE STIFLING
INNOVATION BY REDUCING THE
AMOUNT OF TALENT.
YOU'VE SHOWN WITH NIBIB THERE'S
NO SHORTAGE OF PROGRAMS AND
WE'RE LIMITED BY THE CAP OF
MONEY.
SO IF THAT CAN SOMEHOW BE
RELAYED IN ORDER TO HAVE THE
U.S. POSTDOCS AND THIS ECO
SYSTEM WHETHER THEY'RE STARTING
COMPANIES AND INNOVATION WE HAVE
TO MAKE THE CONNECTION AND MAKE
AND THE NOVE INNOVATION THAT
WILL DRIVE DOWN COST.
I DON'T KNOW HOW TO DO THAT.
>> THAT'S AN IMPORTANT POINT.
IT'S HEARD IN DIFFERENT WAYS AND
DIFFERENT SECTORS AND IMPACTFUL.
WE CAN DREAM UP PROGRAMS AND TRY
TO MEET YOUR NEEDS BUT IF YOU
MAKE CERTAIN DECLARATIONS LIKE
THE ADVISORY COUNCIL TO THE
DIRECTOR, EVERYONE IS QUOTING
THE REPORT.
THIS IS WHAT WE NEED TO DO WITH
POSTDOCS.
I THINK IT'S AN OPPORTUNITY TO
AMEND OR APPEND THE REPORT AND
SAY IT'S GOOD BUT THERE'S
ANOTHER COMMUNITY THAT NEEDS
ADDITIONAL THINGS TO DRIVE
INNOVATION, ENTREPRENEURSHIP,
ECONOMIC GROWTH AND ENSURE WE
ARE CONTINUING TO PRODUCE
TRANSFORMATIONAL TECHNOLOGIES
FOR FUTURE GENERATIONS.
WE WANT TO ADD ON LIKE THE MAIN
NIH MESSAGE BUT WANT TO
CUSTOMIZE IT AND FINE TUNE IT
FOR THE ENGINE MAKING OTHER
THINGS POSSIBLE.
>> AS I LEARNED ON COUNCIL,
YOU'LL BE CONTACTED LATER.
WE WON'T TELL YOU DETAILS NOW.
>> IT'S MY PLEASURE TO INTRODUCE
HECTOR LOPEZ.
HE WAS A WONDERFUL PROGRAM
DIRECTOR IN ULTRASOUND WHO
PASSED AWAY SOME YEARS AGO AND
WE'VE BEEN ABLE TO COMMEMORATE
HIS CONTRIBUTIONS TO OUR
COMMUNITY AND OUR FIELD THROUGH
THIS LECTURESHIP THE ANNUAL
LECTURESHIP.
AND THE SPEAKER AS I'VE ALREADY
PRE-ADVERTISED IS DR. BISI BELL
THE JOHN MALONE ASSOCIATE
PROFESSOR OF ELECTRICAL AND
COMPUTER ENGINEERING AT JOHNS
HOPKINS AND DID HER Ph.D. AT
DUKE IN BIOMEDICAL ENGINEERING
AND HAS HER UNDERGRADUATE IN
MECHANICAL ENGINEERING AT M.I.T.
SHE WAS A POST-DOCTORAL FELLOW
FOR SURGICAL SYSTEMS AND
TECHNOLOGY PRESUMABLY WHERE SHE
LEARNED TO WRITE GRANT PROPOSALS
SUCCESSFULLY.
SHE ESTABLISHED THE
PHOTOACOUSTIC AND ULTRA SONICS
IMAGING LABS ONE OF THE MOST
CLEVER ACRONYMS I'VE SEEN, THE
PULSE LAB.
SHE LEADS A HIGHLY
INTERDISCIPLINARY RESEARCH LAB
WITH ROBOTICS AND MECHANICS AS
WELL AS SIGNAL PROCESSING AND
MEDICAL DEVICES.
THIS IS TO ENGINEER AND DEPLOY
BIOMEDICAL ENGINEERING SYSTEMS
THAT ADDRESS UNMET CLINICAL
NEEDS AND IMPROVE STANDARD OF
PATIENT CARE.
SO DR. BELL IS THE RECIPIENT OF
MANY AWARDS AND FELLOWSHIPS AND
POSTDOC AND RECEIVE THE K99, R00
PATHWAY TO INDEPENDENCE AWARD
AND TRAIL PLAYS -- TRAILBLAZER
AWARD AND SHE'S ONLY ONE OF 4 OF
1500 IN THE PRECEDING DECADE TO
RECEIVE THIS HONOR AS AN
ASSISTANT PROFESSOR.
THAT'S PRETTY IMPRESSIVE.
SHE'S ALSO RECENTLY IN 2024
RECEIVED THE NSF WATERMAN AWARD
THE NATION'S HIGHEST HONOR FOR
EARLY CAREER SCIENTISTS AND
ENGINEER S.
MOST IMPORTANTLY AN E-MAIL CAME
A FEW WEEKS AGO SHE'S BEEN
SELECTED AND HAS AGREED TO,
THANKFULLY, BECOMING THE NEXT
EDITOR-IN-CHIEF OF THE JOURNAL
OF BIOMEDICAL OPTICS.
A JOURNAL I HELPED FOUND IN 1997
OR SO.
WELCOME, BISI AND WE LOOK
FORWARD TO YOUR PRESENTATION.
>> WHILE MY SLIDES ARE LOADING,
THANK YOU, BRUCE FOR THE AWESOME
INTRODUCTION AND IT'S MY HONOR
TO BE HERE AND THE TOPIC IS ON
EQUITABLE ULTRASOUND AND
PHOTOACOUSTIC IMAGING.
HAPPY TO THOSE IN THE MEETING
AND FEEL HONORED TO BE IN YOUR
PRESENCE.
I'M HONORED TO DELIVER THE NAMED
LECTURE BECAUSE AS BRUCE
MENTIONED, HECTOR LOPEZ WAS A
MEMBER OF MY ULTRASOUND
COMMUNITY.
I DID KNOW HIM AND ATTENDED
CONFERENCES WITH HIM.
ONE OF THE LAST BE TO THE ULTRA
SONIC IMAGING AND CHARACTERIZING
CONFERENCE IN 2014 AND SHORTLY
THEREAFTER ALMOST A WEEK LATER
THE SHOCKING NEWS OF HIS
DEPARTURE.
AND THE Ph.D. RESEARCH WAS THE
BASIS OF RECENT GRANTS AND AS A
POSTDOC I HAD TO PUT SOME
TOGETHER MYSELF.
AT THAT TIME IN 2014 I HAD AND
MY EARLIER WORK GOES TO THIS AND
MY STARTED MY LAB THE PULSE LAB
AND WE FOLLOW THE CYCLE OF
INNOVATION AND DEVELOP THEORIES
AND MODELS AND SIMULATIONS TO
HAVE A MATHEMATICAL, PHYSICS
BASIS SIGNAL PROCESSING
TECHNIQUE TO BE APPLIED
INTERCHANGEABLY TO PHOTO IMAGING
USING THE HARDWARE AND SOFTWARE
AS WE'LL SEE AND WE DESIGN
IMAGING PROBES LIKE THE LIGHT
DELIVERY SYSTEM DEVELOPED FOR
TREAT BEING PROSTATE OR IMAGING
AND TAKE OUR DESIGNS TO BUILD
AND TEST PROTOTYPES TO INCLUDE
ULTRASOUND AND PHOTO ACOUSTIC
IMAGE QUALITY AND INTEGRATE OUR
DESIGNS AND PROTOTYPES WITH
ULTRASOUND SYSTEMS AND LASERS
AND ROBOTS TO CREATE A NEW
SYSTEM THAT'S THE FIRST OF IT'S
KIND TO ADDRESS A CLINICALLY
RELEVANT PROBLEM AND TEST THE
SYSTEMS ON PATIENTS AND MAY
LEARN SOMETHING THAT WOULD
REQUIRE US TO REVISIT THIS AND
THE CYCLE CONTINUES FROM THERE.
IT'S EXCITING ALLOWING US TO
CONSIDER ALL POSSIBLE PATIENTS
IN OUR DESIGNS.
WHEN WE LEARN SOMETHING FROM
CLINICAL STUDIES WE CAN DO
MODELLING AND STIMULATIONS TO
ASSESS INDIVIDUAL PATIENT NEEDS.
TO TAKE IT DEEPER INTO SOME OF
THE TWO MAIN TOPICS WE STUDY
I'LL TALK ABOUT IN THE
PRESENTATION AND SO JUST BRIEFLY
THE SYSTEM ALL STN STANDARDS WI
THE HARDWARE OF THE SYSTEM AND
THEN PROBES THAT INTERFACE WITH
DIFFERENT SHAPES.
AND MAY DISPLAY THE SCREEN AND
THE WAY THEY INTERACT IS THE
SCANNER TRANSMITS ELECTRICAL
PULSES TO THE PROBE WHICH
CONTAINS AN ARRAY OF ELEMENTS
CONVERTING THE SIGNALS INTO
PRESSURE WAVES THAT PROPAGATE IN
THE BODY AND REFLECT OFF
STRUCTURES AND RETURN SOUNDS TO
THE PROBE THAT DOES THE
CONVERSION SO THE SOUND IS
CONVERTED INTO ELECTRICALS ARE
SENT TO AN ONBOARD COMPUTER.
AND THE FIRST IS THE BEAMFORMING
STEP AND CONSIDERED THE FIRST
LINE OF SOFTWARE DEFENSE AGAINST
A POOR QUALITY IMAGE AND THE
FOCUS OF MUCH OF MY RESEARCH.
AFTER BEAM FORMING WE PLAY HAVE
SCAN CONVERSION, COMPRESSION,
FIT -- FILTERING AND THEN
DISPLAY ON THE MONITOR.
AND WE CAN GET A PHOTOACOUSTIC
IMAGING SYSTEM AND I TRANSLATE
LASER LIGHTS TO ABSORB THE
LIGHTS AND GENERATES A SOUND
WAVE WE CAN DETECT WITH
CONVENTIONAL ULTRASOUND
TRANSDUCER AFTER THIS OCCURS THE
PROFESSION IS SIMILAR TO WHAT I
TALKED ABOUT ON THE PREVIOUS
SLIDE WHERE THE PROBE CONVERTS
THE SOUND INTO ELECTRICAL
SIGNALS SENT TO A SCANNER FOR
RECEIVING AND PROCESSING AND SEE
THE DEFORMING STEP AND THERE'S
MORE POSTPROCESSING BEFORE THE
PHOTOACOUSTIC IMAGE INTERESTED
FOR DISPLAY.
SO PHOTO SOUND AND PHOTOACOUSTIC
SHARE HARDWARE AND SOFTWARE AND
CAN BE INTEGRATED TO IMPROVE THE
OVER ALL CLINICAL OR SURGICAL OR
HEALTH CARE EXPERIENCE AND
THERE'S A HOST OF OTHER IMAGING
TECHNIQUES THAT EXIST BECAUSE
PHOTOACOUSTIC IMAGING CAN
EXPLOIT A DIFFERENT TISSUE
PROPERTY AND THAT'S THE PROPERTY
OF OPTICAL ABSORPTION.
IT'S BENEFICIAL FOR TARGETING
ANY STRUCTURE WITH A HIGHER
ABSORPTION THAN ITS
SURROUNDINGS.
THIS IS TRUE OF BLOOD VESSELS IN
THE BODY AS WELL AS METAL
IMPLANTS THAT MAY BE INSERTED OR
CONTRAST AGENTS THAT MAY BE
INJECTED IN THE BODY.
WE SEE PHOTOACOUSTIC IMAGING HAS
THE POTENTIAL TO PROVIDE NEW
INFORMATION FOR DIAGNOSTIC
IMAGING, SURGERY AND
INTERVENTIONAL GUIDANCE.
ON TOP OF THAT IT SHARES THE
BENEFITS WITH ULTRASOUND BEING A
COST-EFFECTIVE APPROACH IN
COMPARISON TO OTHER MEDICAL
IMAGING TECHNIQUES.
I WANT TO SHOW IS THE INNOVATION
IN BEAMFORMING DESIGN.
I WANT TO REVIEW THE BEAMFORMING
BASICS.
WE UNDERSTAND WHETHER LIGHT OR
SOUND IS TRANSMITTED THE, LIGHT
CAN BE ABSORBED AND SOUND
TRANSMITTED TO AN ULTRASOUND
PROBE WITH AN ARRAY OF ELEMENTS
IN GRAY.
AND RELEVANT TO THE SOURCE AND
THEN THEY NEED TIME DELAY
APPLIED TO ALL SIGNALS FROM THE
SAME LOCATION ARE REPORTED IN
ONE STRAIGHT LINE THAT CAN BE
SUMMED.
THIS IS THE PROCESS OF
TRADITIONAL THEY ARE AND SUM
BEAMFORMING.
THE AMPLITUDE-BASED APPROACH THE
SIGNAL TELLS US SOMETHING ABOUT
THE SOUND AND THE APPROACH THAT
IS IN ALL THE SCANNERS USED
AROUND THE WORLD TODAY.
AND IF I HAVE A HIGHLY SCATTERED
MEDIUM OR BODY PART I MAY GET A
RANDOM REPORTING ON THE SUBSET
OF ELEMENTS AFTER TIME DELAYS
AND SUMMATION.
IF THIS IS THE ACTUAL SIGNAL I'M
INTERESTED IN YOU CAN IMAGINE
THIS MAY CONFUSE THE
INTERPRETATION OF THE IMAGE
ACOUSTIC CLUTTER.
IT MAKES IT DIFFICULT TO CARRY
OUT OUR DESIGN PROCEDURES.
AND THE BASIC PRINCIPLE IS IF I
CROSS-CORRELATE THE TARGET WITH
IT'S NEIGHBORS I'LL HAVE A HIGH
SPATIAL CORRELATION OR COHERENCE
IF I CROSS CORRELATE THIS WITH
ITS NEIGHBORS I'LL HAVE A LOW
SPATIAL COHERENCE THIS UNDER
LIES THE CONCEPT OF COHERENCE
BASED BEAMFORMING I CREATED AS A
GRAD STUDENT FOR ULTRASOUND
IMAGING AND DEVELOPED FOR
INTERVENTIONAL CASES AS A
POSTDOC AND IT IS THE BASIS OF A
LOT OF WHAT I'LL TALK ABOUT FOR
THE REST OF THE PRESENTATION
WHERE I'LL FIRST TALK ABOUT
EXAMPLES OF THE COHERENCE-BASED
APPROACH TO BEAMFORMING IN
DIAGNOSTIC IMAGING, SURGERY AND
IMAGE-GUIDED INTERVENTIONS AND
COMPUTATIONS INVOLVED AND END
WITH A SUMMARY AND OUTLOOK.
YOU SEE ON THE TOP AN IMAGE
CREATED FROM A PATIENT IS A
BEATING HEART WE CAN SEE THERE'S
ACOUSTICS FROM THE CHEST WALL
CAUSING CLUTTER THAT OVERRIDES
THE BEATING HEART OF INTEREST
AND WHEN WE TAKE THE COHERENCE
BASED APPROACH WE CAN SEE THE
ENDOCARDIAL BORDERS MORE BROADLY
AND PROVIDES IMPROVED QUALITY TO
OVERWEIGHT OR OBESE WHO CREATE
MORE SCATTERING AND ACOUSTIC
CLUSTER AND YOU CAN SEE IN THIS
EXAMPLE WE CREATE THESE TYPES OF
IMAGING WITH THE AMPLITUDE BASED
APPROACH AND FLUID AND SOLID
MASS MAY APPEAR SIMILARLY DARK.
IF WE AND THERE'S LOWER QUO --
COHERENCE AND THE SOLID MASS HAS
A SIMILAR APPEARANCE AND THIS
COULD BE USEFUL TO DETERMINE ON
THE SPOT IN REAL TIME WHETHER A
MASS IS BENIGN OR REQUIRES
FURTHER INVESTIGATION.
AND WITHOUT THE ABILITY TO DO
THIS THEY CAN WAIT UP TO TWO
YEARS TO DETERMINE THE MASS OR
MAY UNDER GO BIOPSIES OR
ASPIRATIONS.
WE'RE OFFERING A TECHNOLOGY TO
REDUCE ALL OF THESE EFFECTS AND
PROMGSING FOR WOMEN WITH DENSE
BREAST WHO HAVE BREAST DENSE
TISSUE AND THANK YOU FOR THE RO1
THAT SUPPORTS THIS IDEA.
IT'S NOT LIMITED TO CARDIAC AND
BREAST IMAGING.
SEVERAL COLLEAGUES HAVE SHOWN
SIMILAR BENEFITS IN MULTIPLE
CASES SUCH AS IN LIVER IMAGING
THE VESSELS YOU CAN SEE WITH THE
COHERENT BASED APPROACH FOR
DIAGNOSING FATTY LIVER DEED AND
IMPLICATIONS FOR MATERNAL HEALTH
AND SEE THE FETAL HEART MORE
CLEARLY WITH THE COHERENCE BASED
APPROACH THAN WITHOUT AND
SIMILARLY SMALLER VESSELS THE
CAROTID ARTERY TO IMPROVE THE
CARDIOVASCULAR HEALTH
ASSESSMENT.
AND THIS COHERENCE BASED
APPROACH IS CALLED SLC WHICH
STANDS FOR SPATIAL COHERENCE
IMAGING.
THIS APPROACH COULD BE
INTERCHANGED NOT ONLY FOR
ULTRASOUND IMAGING BUT FOR OTHER
ACOUSTIC IMAGING WHERE INITIALLY
STARTED SHOWING APPLICATIONS AND
INTERVENTIONAL IMAGING AND I
SHOWED HOW IT WOULD ADDRESS A
PRIVILEGED WORLD WITH IN THIS
CASE PHOTOACOUSTIC IMAGING.
AS MANY IN THE OPTICS FIELD KNOW
WHEN YOU HAVE A HIGHER CONTENT
IN TECHNOLOGY YOU TEND TO SUFFER
IN VARIOUS WAYS AND IN
PHOTOACOUSTIC IMAGING THIS IS NO
DIFFERENT WHERE THE PENETRATION
DEPTH CAN BE LIMITED BECAUSE OF
MELANIN HAS A HIGHER ABSORPTION
AND WHEN HAVE YOU A DARKER SKIN
TONE YOU HAVE A HIGHER
ABSORPTION OF MELANIN AND THIS
CAUSES TWO INTERACTIONS OF THE
PHOTOACOUSTIC EFFECT.
WHEN THE PHOTOACOUSTIC EFFECT
OCCURS THE SOUND GOES FORWARD
AND BACKWARD.
AS THE BACKWARD PROPAGATION
GIVES HIGH AMPLITUDE SIGNALS
WITH THE APPROACH TO IMAGING.
BUT THE FORWARD PROPAGATION
TENDS TO BE MORE PROBLEMATIC THE
SOUND TO SCATTER INTO STRUCTURES
AND CAUSE ACOUSTIC CLUTTER TO
OVERRIDE THE SIGNALS OF
INTEREST.
AND WE CAN REDUCE THE ACOUSTIC
CLUTTER A RANGE OF SKIN TONES
AND CAN ADDRESS SKIN TONE BIAS
WITH TECHNIQUES AND CAN ADDRESS
THAT WITH COHERENCE-BASED
FORMING TO IMPROVE IMAGE QUALITY
ESPECIALLY IN PATIENTS WITH
DARKER SKIN TONES.
THESE ARE FROM THE FOUR ARMS OF
VOLUNTEERS.
IT CAN BE APPLIED TO THE
EMERGING AREA OF PHOTO ACOUSTIC
BREAST IMAGING STARTING WITH
SIMULATIONS.
HERE WE HAVE PREVIOUSLY
VALIDATED BREAST TISSUE MODEL
WITH A WATER LAYER UP HERE AND
SOME SKIN AND FAT TISSUE AND
INCLUSION OF INTEREST.
WE CAN TAKE THE MODEL THERE'S
SKIN OPTICAL ABSORPTION
PROPERTIES WITH WAVE LENGTHS
ACCORDING TO THE VALIDATED
EQUATION AND CAN GET MAPS OF
ABSORBED ENERGY DENSITY AND TAKE
THIS TO CREATE PHOTOACOUSTIC
IMAGES OF DIFFERENT VIRTUAL
PATIENT WITH DIFFERENT
APPRECIATES.
SO FROM THE TOP TO BOTTOM YOU
SEE THE PROPERTY AND WHAT
HAPPENS WITH DIFFERENT SKIN
TONES AND FROM LEFT TO RIGHT ON
THE IMAGES OF THE VIRTUAL
PATIENTS WITH DIFFERENT WAVE
LENGTHS.
THERE'S THREE FEATURES I WANT TO
SHARE FROM THIS PARTICULAR
IMAGE.
THE FIRST BEING THAT WHEN WE
LOOK AT THE LOWEST WAVE LENGTH
WE CAN APPRECIATE AS WE INCREASE
THE SKIN TONE SO IT DARKENS,
IT'S MORE DIFFICULT TO SEE THE
STRUCTURE OF INTEREST AS
REMINDER IS THIS YELLOW
INCLUSION FROM THE GROUND TRUTH
MODEL.
THEN SOME HAVE MORE BETTER IMAGE
QUALITY THAN OTHERS.
WE TAKE A LOOK AT THE 8/10 WAVE
LENGTH WE CAN SEE IT MORE
CLEARLY BUT THE PROBLEM OF NOT
BEING ABLE TO SEE IT WITH DARKER
SKIN TONES STILL PERSISTS.
AND THEN THE THIRD TAKEAWAY FROM
THE IMAGE IS IF WE GO TO HIGHER
WAVE LENGTHS WHERE THE OPTICAL
ABSORPTION DOMINATES THAT OF
SKIN THE TARGET WE WANT TO SEE
APPEARS HARD TO SEE AT ALL OF
THE STRUCTURE OR ALL THE
PATIENTS WITH DIFFERENT SKIN
TONES.
THESE ARE THE THREE TAKEAWAY
POINTS FOR THE REALISTIC BREAST
MODEL BECAUSE IT'S A SIMULATION
WE CAN DO THINGS THAT WOULD NOT
HAPPEN IN REAL LIFE LIKE REMOVE
THE SKIN COMPLETELY.
WHEN WE DO THAT WE CAN SEE THE
IMAGE IS BETTER THAN THE IMAGE
EVEN WITH THE LIGHT SKIN TONES.
THIS RESULT FROM MY LAB IS ONE
THAT FURTHER VAL DATES SKIN IS
PRIMARILY RESPONSIBLE FOR THE
PRESENCE OF ACOUSTIC CLUTTER
REGARDLESS OF SKIN TONE OR WAVE
LENGTH.
ONE COMMON DESIGN IS TO SUSPEND
THE BREAST LIKE IN A WATER
FILLED DEVICE LIKE YOU SEE ON
THE SCREEN AND WOULD HAVE
SENSORS AND LIGHT COMING IN IN
ORDER TO DO MAKE THE
PHOTOACOUSTIC AFFECT AND GET THE
IMAGE AND APPRECIATE HOW DARKER
SKIN TONES ARE EXPECTED.
AND WE DEMONSTRATED BY
VISUALIZATION THE VESSELS UNDER
THE PALM OF THE PERSON'S HAND.
WE GET NICE IMAGES AND CAN
APPRECIATE IF WE HAVE MELANIN
ABSORBING WE COULD NOT GET SUCH
NICE IMAGES.
THIS IS TRUE IN MOLECULAR
IMAGING CONTRASTING THE AGENT
AND VISUALIZE THE GROUP TAKE
OVER TIME SEEING MORE OVER TIME.
WHEN WE INSERT OUR PROBES INSIDE
THE BODY WE SEE A DESIGN WHERE
WE HAVE A LIGHT SOURCE ATTACHED
TO ULTRASOUND CATHETER THAT CAN
BE INSERTED INTO A VESSEL AND
SPIN AROUND OR LOOK AT THE
CHALLENGES THAT EXIST ONE IS TO
BREAK THE RIGIDITY AND SEPARATE
THE LIGHT SOURCE FROM THE
ACOUSTIC RESOURCE.
AND ONE REASON WE DO THIS IS FOR
THE NOVEL APPLICATION OF
SURGICAL GUIDANCE.
THE CONCEPT IS THE SURGICAL TOOL
IS TYPICALLY MADE OF METAL WITH
HIGH ABSORPTION AND CAN INSERT
THE TOOL TIP AND UNDERLYING
STRUCTURE OF INTEREST WE DO NOT
WANT TO INJURY DURING A SURGICAL
PROCEDURE OTHERWISE HIDDEN BY
TISSUE.
ACCIDENTLY INJURY COULD BE
CATASTROPHIC WHICH MOST LIKELY
NOT BE SEEN SO THEON OF -- THE
SURGEON HAS TO RELY ON
EXPERIENCE TO NOT HIT THE
STRUCTURE THEY SHOULD NOT BE
HITTING.
AND WE HAVE THIS MOCK SURGICAL
ENVIRONMENT WHERE THE TWO BLACK
LINES HAVE CAROTID WE DON'T WANT
TO INJURY AND SEE WHERE THE TOOL
TIP IS LOCATED IN RELATIONSHIP
TO THE MOCK ARTERIES.
THIS GIVES US THIS CONFIDENCE TO
CORRELATE WHAT WE SEE IN THE
PHOTOACOUSTIC IMAGE WITH WHAT IS
TAKING PLACE IN THE SURGICAL
FIELD.
AS WE ALL KNOW A REAL SURGICAL
FIELD IS NOT AS SIMPLE AS THIS.
WE CAN'T SEE THE STRUCTURES WE
DON'T WANT TO INJURY AND COVERED
THE MOCK VESSELS WITH BONE AND
IT SHOWS WHAT WOULD HAPPEN IN
THE ACCOMPANYING PHOTOACOUSTIC
IMAGE SEEING THE SAME
INFORMATION AND THAT IS THE
INFORMATION WHERE THE TOOL TIP
IS IN LOCATION TO THESE MAJOR
STRUCTURES WE DON'T WANT INJURE
AND CAN FORESEE THERE'S NO
STRUCTURE IN THE FIELD OF VIEW
IN THE IMAGE OR PROCEED WITH
WHEN WE SEE THE TOOL IS LOCATED
NEXT TO ONE OF THE STRUCTURES.
WE CAN USE SIMULATIONS TO
UNDERSTAND HOW TO DESIGN OUR
PROCEDURE.
WE HAVE THE VIRTUAL WORLD OF
SIMULATIONS TO UNDERSTAND
MULTIPLE PARAMETERS ABOUT OUR
SYSTEM DESIGNS.
ONE OF THESE PARAMETERS IS
FEATURED HERE AND THAT IS WHAT
DOES THE LIGHT PROFILE WITH
DISTANCE FROM THE TISSUE
SURFACE.
WE CAN MODEL THAT IN SIMULATION
AND PHOTOGRAPH AND GET NICE
CONFIRMATION WHAT WE DESIGN IS
WHAT IS PRODUCED AND WE CAN
DESIGN AROUND THINGS LIKE HOT
SPOTS AND BUILD INTO THE SIGNAL
PROCESSING TECHNIQUE AND WE CAN
USE SIMULATIONS TO UNDERSTAND
WHERE WE CAN PLAY OUR ACOUSTIC
RESOURCE.
THERE'S THREE POSSIBLE LOCATIONS
WITH THE SAME CADAVER SKULL I
EXPERIMENTED ON AND BUILT A
MODEL OF TO DEMONSTRATE THE
POTENTIAL FOR PATIENT SPECIFIC
ACOUSTIC SIMULATIONS.
THE SKULL I TOOK A CC IMAGE OF
AND RECONSTRUCTED AND PLACED
ACOUSTIC SENSORS AND WHAT EACH
DOT REPRESENTS.
THE COLOR REPRESENT THE MAXIMUM
PRESSURE RECEIVED FROM EACH
SENSOR.
THERE ARE THREE AREAS WHERE WE
MIGHT WANT TO PLAY OUR ACOUSTIC
SENSOR TO THE RESULTING PHOTO
ACOUSTIC SIGNAL.
THE THREE LOCATIONS ARE THE
EYES, NOSE AND THE TEMPORAL
REGION OF THE SKULL.
WE PERFORMED EXPERIMENTS WITH
THE SAME SKULL WE TOOK A CT
IMAGE OF AND FIRST PLACED THE
FIBER IN THE NOSE WHICH IS THE
LOCATION WHERE THE SURGERY IS
PERFORMED.
IT'S A MINIMALLY INVASIVE
SURGERY PERFORMED THROUGH THE
NOSE.
WE HAVE OUR ACOUSTIC SENSORS.
FIRST THE TEMPORAL REGION OF THE
SKULL AND NOSE AND OCULAR REGION
WITH AND WITHOUT EYEBALLS
INSERTED IN THE SKULL.
AND ON THE WE CAN NOW GET
MATCHED PHOTO ACOUSTIC AND CT
IMAGES IN COLOR AND CT IN GRAY
SCALE AND WE CAN OVERLAY AND
REGISTER THEM TOGETHER AND WHEN
WE DO THAT WE SEE THE PHOTO
ACOUSTIC IMAGE GIVES INFORMATION
WHERE THE INTERNAL CAROTID
ARTERIES ARE LOCATED.
THIS TELLS US THE TECHNOLOGY IS
BENEFICIAL FOR GUIDING THIS
MINIMALLY INVASIVE SURGICAL
PROCEDURE.
ONE KEY FEATURE IS THAT EVEN
THOUGH WE SEE FROM THE ACOUSTIC
SIMULATIONS YOU MAY NOTICE THE
PHOTO ACOUSTIC IMAGE HAVE THE
SAME AMPLITUDE REGARDLESS OF THE
LOCATION OF THE ACOUSTIC
RECEIVER BECAUSE THE APPROACH I
TALKED ABOUT IS USED TO DISPLAY
THE IMAGE BECAUSE ULTIMATELY ALL
WE CARE ABOUT IS WHERE IS THE
VESSEL LOCATED.
WE DON'T CARE ABOUT THE
AMPLITUDE OF THE VESSEL AND THE
COHERENCE ALSO IGNORES AMPLITUDE
BECAUSE IT JUST TELLS US IF OUR
SIGNAL IS COHERENT OR NOT.
IT WITH US A MINIMALLY INVASIVE
PROCEDURE PERFORMED THROUGH THE
NOTION.
THIS LAUNCHED MY POSTDOC CAREER
AND THANK YOU TO MY PROGRAM
OFFICER FOR THAT AWARD.
AND AS I WAS WORKING ON THIS THE
PUBLICATION CAME OUT IN 2015
SHORTLY AFTER THE K99 WAS FUNDED
AND REALIZED IT'S NOT LIMITED TO
NEURO SURGERY BUT SURGICAL
GUIDANCE THAT CAN BENEFIT FROM
THE SAME CONCEPT.
THIS IS WHAT LED TO THE
DEVELOPMENT AND EXPLORATION OF
OTHER SURGICAL PROCEDURES
THROUGHOUT MY TIME AS AN
ASSISTANT PROFESSOR.
I WON'T HAVE TIME IT GET INTO
ALL THESE DIFFERENT PROCEDURES
TODAY BUT THEY ARE NICELY
SUMMARIZED IN THE PERSPECTIVE IN
THE JOURNAL OF APPLIED PHYSICS
IF YOU'D LIKE TO LEARN MORE.
I WILL TALK ABOUT FOR THE NEXT
FEW SLIDES THE CASE WHERE WE
WERE THE FIRST IN THE WORLD TO
INTEGRATE PHOTOACOUSTIC IMAGE
WITH THE DA VINCI IMAGE AND TALK
ABOUT CATHETER PROCEDURE.
LET'S FOCUS ON THE APPLICATION
OF ROBOTIC SURGERIES FOR NOW
WHERE THE SURGERIES ARE
PERFORMED WITH THE DA -- DA
VINCI ROBOT AND THE MOTION OF
THE SURGEON'S HANDS TRANS FER TO
SURGICAL TOOLS MOUNTED ON ROBOT
ARMS INTO KEY HOLE LIKE
INCISIONS AND OUR GOAL IS A
SYSTEM WITH A SPECIALIZED LIGHT
DELIVERY SYSTEM ATTACHED TO ANY
ONE OF THE DA VINCI TOOL KITS
AND THIS IS AN IMAGE OF ABOUT
WHAT THE SURGEON MIGHT SEE WHEN
SWEEPING THE TOOL AROUND THE
SURGICAL WORK SPACE TO DETERMINE
WHERE TO MAKE AN INCISION.
AND YOU CAN SEE THERE IS A
PHOTOACOUSTIC STRUCTURE AND ONE
WHEN THE SURGEON MOVES AWAY.
THIS IS THE CONCEPT THAT UNDER
LIES THE APPROACH FOR
PHOTOACOUSTIC GUIDED
HISTORIERECTOMIES ONE OF THE
MOST COMMON PROCEDURES WITH THE
DA VINCI ROBOT AND WANT TO
SEPARATE THE UNTERINE ARTERIES
WHILE KEEPING THE URETER AND WE
CAN BUILD A PHOTOACOUSTIC
IMAGING SYSTEM FOR GUIDANCE OF
HIST
AND IT THE SOUND CAN ALERT THE
SURGEON THEY'RE TOO CLOSE AND
HAVE VISUAL CUES TO AUDITORY
INFORMING TO THE SURGICAL
GUIDANCE TECHNIQUE AND THANKFUL
FOR THE FUNDING OF THE WORK AND
ONE THING I NEED TO DO IS THE
FACT WE HAVE AN AGENT AND NEED
TO DISTINGUISH THAT FROM WHAT
APPEARS BECAUSE OF THE UNTERINE
ARTERY AND AND THE MIXING IS
WITH WAVE LENGTHS AND THROUGH
SURGERY WE DISAPPOINT HAVE THE
LUXURY TO WAIT AND WE ARE
WAITING ON AN ACOUSTIC BASE THAT
REQUIRES TWO WAVE LENGTHS AT
MAXIMUM AND WE WOULD ACQUIRE
RADIO FREQUENCY DATA SENSED BY
THE ULTRASOUND ELEMENTS AND
FILTER THE INCOHERENT NOISE AND
SEPARATE SIGNAL FROM CLUTTER AND
CAN LOOK AT WHAT WAS DEVELOPED
IN MY LAB AND ULTIMATELY IT'S A
SIMILAR COHERENCE CONCEPT THAT
ALLOWS US TO SEND IN SIGNALS
BEFORE WE KNOW WHICH ONE IS FROM
THE CONTRAST AGENT AND FROM THE
BLOOD.
THE NEXT SERIES OF STEPS ARE TO
TELL US WHICH SEGMENTED SIGNALS
IS BLOOD OR BLUE.
THE STEPS ARE IQ DEMODULATION
AND STACKING OF SPECTRUM AND
PRINCIPLE COMPONENT ANALYSIS AND
WHAT IS BASED ON PRIOR KNOWLEDGE
AND THEN WE'RE READY TO CLASSIFY
THE DATA TO DETERMINE WHICH
SIGNALS IS BLOOD VERSUS METHYL
AND BLUE AND THE X AND Y IS THE
APPROACH AND THE POLY BAR IS THE
ACCURACY FOR EACH WAVE LENGTH
AND THE RESULT IS FIVE MORE
COMMON METHODS A THROUGH E.
WE SEE MULTIPLE COMBINATIONS OF
ONLY TWO WAVE LENGTHS WERE ABLE
TO ACHIEVE SIMILAR ACCURACY TO
APPROACHES A AND B SHOWN HERE
WHICH REQUIRED 12 WAVE LENGTHS
AND WE GET BETTER ACCURACIES
THAN THE OTHER METHODS C, D AND
EVERY.
SO THIS IS EXCITING FOR
CUSTOMIZING HOW TO TREAT
PATIENTS DURING SURGERY TO AVOID
ACCIDENTAL INJURY.
AND WE CAN APPRECIATE THE
BENEFITS OF THE COHERENT SPACE
IN THIS AS WELL.
THIS APPROACH IS NOT ONLY
PROMISING FOR SURGICAL GUIDANCE
BUT FOR ANY IMAGE-GUIDED
INTERVENTION.
FOR EXAMPLE, THIS COULD BE
NEEDLE BIOPSIES OR CATHETER
REPLACEMENTS AND STARTING WITH
THE IMAGING SYSTEM TO OUR ROBOT
ARM AND CAN INSERT OUR OPTICAL
FIBER INTO A CATHETER AND
TOGETHER THIS CREATES A NEW
SYSTEM THAT ALLOWS US TO
AUTONOMOUSLY STAY CENTERED ON
THE CARDIAC CATHETER TIP OF
INTEREST AND FOR DEMONSTRATION
THE SYSTEM IN ACTION WHERE IN
THIS CASE THIS IS ME AGAIN I'M
RETRACTING A CATHETER FIBER HERE
INSERTED IN THE ANIMAL MODEL IN
THE VAIN OF THIS ANIMAL, THE JUK
LAR MAIN AND THE PROBE IS
FOLLOWING THE MOTION.
THIS WOULD BE WHAT THE OPERATOR
WOULD DO TO ULTIMATELY GET TO
THE HEART IN ORDER TO TREAT SOME
FORM OF HEART DISEASE.
ON THE PHOTO ACOUSTIC YOU SEE
NOT SO CLEARLY BUT CAN SEE SOME
SIGNALS THAT ARE ULTIMATELY THE
SIGNALS SEGMENTED AND IT'S
COMMON IT'S COMMANDING THE ROBOT
TO KNOW WHERE TO GO IN ORDER TO
STAY CENTERED.
THE ULTIMATE GOAL IS TO MAKE IT
TO THE HEART AND WE SUCCESSFULLY
ACCOMPLISHED THE GOAL AS SHOWN
ON THE SLIDE AND THE CARDIAC
CATHETER TIPS AS THEY'RE BEING
TRACKED FROM VEINS TO HEART THIS
IS TYPICALLY DONE WITH FLEUROS
COPY AND WHEN WE WANT TO USE
ULTRASOUND WHICH DOES PROVIDE
FORMATION WE WANT TO CHALLENGE
WHILE THE CATHETER MAY BE FINE
FOR SOME ULTRASOUND IMAGES IT
CAN BLEND WITH THE BACKGROUND OF
THE TISSUE AND LOSE
VISUALIZATION OF THE TIP AND FOR
THE PHOTOACOUSTIC WITH THE LASER
AND THIS TIME THE PIPER'S --
FIBER'S IN THE CATHETER WE GET
THE RESULT ON THE RIGHT SEEING
THE TIP OF THE CARDIAC CATHETER
REGARDLESS OF THE CONTACT WITH
TISSUE.
AND SO THIS ENTIRE CONCEPT SHOWS
US THAT WE CAN POTENTIALLY
REPL
REPLACE FLUOROS COPY AND IF WE
HAVE A PHOTOACOUSTIC SYSTEM
WHERE WE WANT TO USE IT TO
REPLACE IT WE WOULD WANT TO HAVE
THE SYSTEM AS UNOBTRUSIVE AS
POSSIBLE.
WE WANT TO HAVE THE ROBOTS
MOUNTED ON THE BODY AND ON THE
LASER IMAGING FRONT THE SMALLER
LASERS TEND TO DELIVER LOWER
LASER ENERGIES AND THAT MEANS
LOWER SIGNAL TO NOISE RATIO AND
RUN INTO THE PROBLEM OF NOT
BEING ABLE TO SEE THE SIGNAL OF
INTEREST IF WE GO TOO SMALL.
WE RECAP WHAT WE'RE TRYING TO DO
AND INSERT THE OPTICAL FIBER IN
THE HEART AND RECEIVE A
PHOTOACOUSTIC SIGNAL WITH A LOW
LASER ENERGY AND APPLY AN
AMPLITUDE BASED APPROACH AND ON
THE TOP LEFT WE GET CORE SIGNAL
TO NOISE RATIO ON THE RIGHT WE
SEE THE TIP OF THE CATHETER MORE
CLEARLY WHICH IS USEFUL FOR
GUIDING THE ROBOT AND TO HIGHER
ENERGY SIMILARLY THE APPROACH
GIVES US A STRONGER SIGNAL AND
TELLS US WHERE THAT CATHETER TIP
IS LOCATED.
AND THE CATHETER TIPS WITH LOW
ENERGIES IS POSSIBLE WITH THE
COHERENCE BASED APPROACH.
WE'RE NOW LOOKING TO APPLY THIS
TO THE EMERGING AREA OF FLEXIBLE
ARRAY TECHNOLOGY WHICH WOULD
ALLOW US TO CONFIRM TO BODY
SHAPES AND SIZES FOR WEARABLE
HEALTH APPLICATIONS.
AND IT INTRODUCING THE CHALLENGE
OF NOT KNOWING OUR ARRAY SHAPES
WE CAN APPRECIATE THE IMAGES WE
GET A DIFFERENT SIGNAL THAN WITH
INCORRECT ARRAY SHAPE.
SO ONE OF THE WAYS WE'RE TRYING
TO ADDRESS THIS IS TO SAY WHAT
IF WITH JUST MAKE GUESSES OF OUR
SHAPE AND THEN CALCULATE THE
RESULTING COHERENCE AT THE ED
SIGNALS RECOGNIZING WHEN
SHARABLE COHERENCE IS MAXIMIZES
IT CAN BE USED TO SAY THIS IS
THE SHAPE OF MY FLEXIBLE ARRAY.
MAXIMIZING COHERENCE MAKES THE
SHAPE POSSIBLE AND IT ALLOWS US
TO ESTIMATE SOUND AS A FUNCTION
OF THE DIFFERENT ARRAY SHAPES.
USING THIS INFORMATION WE CAN
MAKE IMAGES OF THE SIGNALS OF
INTEREST SUCH AS THE FIRST
DEMONSTRATIONS SHOWN IN MY LAB
AND IN THIS CASE WE HAVE THE
IMAGE OF OPTICAL FIBER INTO A
NEEDLE.
AND ON THE TOPIC OF REAL TIME
IMAGING FOR THE MULTIPLE
INTERVENTIONAL AND SURGICAL AND
DIAGNOSTICS, WE WON'T TO GIVE
SPECIAL ATTENTION AND
APPRECIATION TO HOW THE
DIFFERENCE SIGNAL PROCESSING
TECHNIQUES, HOW MUCH TIME IT
TAKES FOR THEM TO FORM THE
IMAGES.
IF WE LOOK AT THE REPRESENTATION
THE SIGNAL IS RECEIVED BY MANY
ELEMENTS NOT JUST A FEW THE
FIRST STEP IS DELAY THE SIGNALS
AND IF WE WANT TO TAKE THE SHORT
LIFE SPECIAL COHERENCE APPROACH
A WINDOW WOULD DELAY SIGNALS IN
TIME AND CROSS CORRELATE IN
SPACE AND ASK OURSELVES HOW
SIMILAR THEY ARE TO THE
NEIGHBORS AND THIS IS THE
MEASURE OF SEPARATION.
0 TO M-MINUS 1 AND THE NUMBER OF
ELEMENTS IN THE ARRAY AND MAY
GET A SPECIAL COHERENCE FUNCTION
THAT LOOKS LIKE THIS AND CAN
THEN INTEGRATE THE FUNCTION IN
THE SHORT LAG REGION WHERE THE
NAME COMES FROM AND THIS GIVES
US MORE PIXEL.
WE CAN REPEAT THIS FOR MULTIPLE
DEPTHS IN OUR RECORDED CHANNEL
DATA AND CAN DO THIS FOR
MULTIPLE LEFT AND RIGHT
POSITIONS AND BUILD UP AN IMAGE
THAT WAY.
WE APPRECIATE THE COMPLEXITY OF
THIS PROCESS RELATIVE TO THE
TRADITIONAL DELAY AND SUM WHICH
WILL GIVE A DIFFERENT IMAGE, AN
AMPLITUDE BASED IMAGE.
WE CAN APPRECIATE FROM THE STEPS
IT'S THE CORRELATION CALCULATION
STEP THAT'S THE MOST TIME
INTENSI
INTENSIVE.
THIS IS THE STEP WE IN MY LAB
HAVE FOCUSSED ON REPLACING AND
SPEEDING UP WITH DEEP NEURAL
NETWORKS.
AND LEARNS THE SPATIAL COHERENCE
FUNCTION DIRECTLY FROM THE
RECORDED CHANNEL DATA.
THEN ONCE WE LEARN WE BELIEVE
WE'RE LEARNING BASED ON THE
PHYSICS OF THE WAVE PROPAGATION
AND TRAINED WITH MILLIONS OF
EXAMPLES AND ARE ABLE TO GET
THOSE MILLIONS OF EXAMPLES
BECAUSE WE NEED TO SLICE OUR
DATA IN DIFFERENT AXIAL
DIMENSIONS AND ONLY NEED A SMALL
SLITHER OF DATA.
THIS ALLOWS US TO TAKE TWO
PATHWAYS.
ONE IS THE MORE TRADITIONAL
COMPUTATIONAL PATHWAY AND THE
OTHER IS THE NEWER PATHWAY TO
GET THE IMAGE AND THESE ARE
EXAMPLES FROM BREAST MASSES AND
CAN SEE COMPARE AM IMAGE WITH
THE IMAGE TO IMAGE CORRELATION
OVER THE ENTIRE TEST SET AND
ALSO ACHIEVE OUR GOAL OF THE
PROCESS IT TAKES TO CREATE THE
SLS.
AND WE TOOK A CLOSER LOOK UNDER
THE HOOD AT WHAT THIS DEEP
NEURAL NETWORK IS DOING WE HAVE
IN DARK BLUE THE ORIGINAL
COHERENCE FUNCTION AND IN
LIGHTER BLUE THE OUTPUT.
THIS IS THE FUNCTION WE
INTEGRATE IN ORDER TO GET OUR
SLSC IMAGES.
WE CAN APPRECIATE FROM THE
COMPARISON WE HAVE PERFORMANCE
IN THE SHORTER LAG REGION BY
DESIGN OF HOW WE TRAIN OUR
NETWORKS AND PENALIZE ERRORS IN
THE SHORT LAG REGION MORE
SEVERELY AND USING THE SHORT LAG
INFORMATION IN ORDER TO MAKE THE
IMAGES.
AND THE SAME CONCEPT OF THE DEEP
NEURAL NETWORK APPROACH TO
COHERENCE BEAMFORMING CAN BE
APPLIED TO PHOTOACOUSTIC IMAGING
WHERE THE FUNCTIONS IN THIS
SLIDE ARE LEARNED AND
TRADITIONAL FUNCTION IS SHOWN IN
BLUE AND THE OUTPUT IS SHOWN IN
RED.
AND WE CAN SEE WITH THE APPROACH
WE CAN REDUCE THE CLUTTER AND
SKIN TONE BIAS IN THE IMAGE I'M
RESHOWING HERE FOR COMPARISON.
WE ALSO SEE INTERESTINGLY
BECAUSE IN THIS MODIFIED DEEP
NEURAL NETWORK WE SMOOTH OVER
SOME OF THE BUMPS YOU SEE AS A
COMPUTATIONAL APPROACH AND WITH
THE SMOOTHER COHERENCE FUNCTION
WE REDUCE THE CLUTTER PRESENT IN
THE OTHERWISE COMPUTATIONALLY
INTENSIVE SPATIALLY FUNCTION.
AND COHERENCE BASED TECHNIQUES
ENABLE MORE EQUITABLE ULTRASOUND
AND PHOTOACOUSTIC IMAGING AND
APPLICATIONS CAN RANGE FROM
DIAGNOSTIC TO SURGERY AND
MINIMALLY INVASIVE INTERVENTIONS
AND APPRECIATE HOW TO DO THIS
WITH PATIENT-SPECIFIC SOFTWARE
AND HARD WARE AND UNDERSTAND
BODY CHARACTERISTICS AND CAN
CREATE HARDWARE TO CATER TO S IN
PATIENTS AND SHOWN DIVERSITY
DRIVES INNOVATION.
NOT ONLY DIVERSITY OF THOUGHT
BUT OF OUR DATA SETS.
IF WE'RE PLANNING FOR TECHNOLOGY
THAT IMPROVES QUALITY WE WANT TO
MAKE SURE ALL TYPES OF PATIENTS
ARE REPRESENTED IN THE DATA SET
THAT WE'RE ANALYZING TO SAY
WE'VE IMPROVED IMAGE QUALITY.
THIS INCLUDES WE WANT TO MAKE
SURE WE INCLUDED MULTIPLE BODY
SHAPES AND WEIGHTS.
WE WANT TO MAKE SURE WE
RECRUITED DENSE BREAST TISSUE
WHICH TENDS TO REPRESENT A
CURRENTLY UNDER SERVED PATIENT
POPULATION IN THE CANCER
DIAGNOSTIC WORLD AND WE WANT TO
MAKE SURE WE HAVE THE DARKER
SKIN TONES WHEN DEALING WITH
OPTIC-BASED TECHNOLOGIES BECAUSE
WE KNOW HOW IT CAN SUFFER IF WE
DON'T CONSIDER THESE MULTIPLE
VARIATIONS.
THIS DOVETAILS NICELY WITH THE
IMPORTANCE OF DIVERSITY WITH
RESPECT TO DEEP LEARNING AND THE
NEED TO CONSIDER EVERYONE IN OUR
TRAINING DATA SETS AND IN THE
ENTIRE TRAINING PROFESSION.
-- PROCESS.
AND THE PERSONNEL IN MY LAB WITH
DISTRIBUTION OF MY CURRENTS
Ph.D. AND POSTDOCS COME FROM
JOHN HOPS KIN AND I VALUE THE
DIVERSITY OF BACKGROUND AND THE
TYPES OF PROBLEMS AND QUESTIONS
THEY WANT TO ASK AND THIS ALSO
FEEDS INTO THE PROBLEMS AND
SOLUTIONS WE COME UP WITH AND
THIS IS BACKGROUND NOT ONLY IN
DEGREES BEING SOUGHT BUT ALSO
DEGREES AND INFORMATION THEY
BRING TO THE PROBLEMS BEING
ADDRESSED AND THIS EXAMPLE OF MY
BACKGROUND IN TERMS OF DEGREES I
HAVE AND DEPARTMENTS I'VE BEEN
AFFILIATED WITH OVER MY CAREER
AS A LAB DIRECTOR AND THIS ALSO
FIELDS THE TYPES OF QUESTIONS
I'M ABLE TO SUPPORT MY QUESTIONS
IN THEIR INVESTIGATIONS.
ON THE NOTE OF FURTHER
SUPPORTING EQUITY AND DIVERSITY
WE MADE PUBLICALLY AVAILABLE
PHOTOACOUSTIC RESOURCES.
FOR EXAMPLE IN THE ULTRASOUND
TOOL BOX IT'S AVAILABLE FOR
ANYONE TO USE FOR RESEARCH USE.
AND THE PHOCO SPACE SOFTWARE
HELPS US UNDERSTAND THE NUANCES
IN THE ULTRASOUND IMAGING
INITIALLY DEVELOPED TO
PHOTOACOUSTIC IMAGING AND I ALSO
LED A CHALLENGE FOR THE ENTIRE
COMMUNITY TO ADDRESS TO THE SAME
CHALLENGE AND SHARE THE
RESOURCES WITH THE TRAINING DATA
AND BEST SOLUTIONS ALL AVAILABLE
FOR ANYONE TO USE AND I BELIEVE
THIS ALLOWS US TO LOWER BARRIERS
FOR ENTRY INTO THE FIELD WHICH
IS ALSO IMPORTANT IF WE WANT TO
EXCITE OUR STUDENTS AND OUR
POSTDOCS TO ENTER THE NEW FIELD
TO COME UP WITH NEWER, CLEVER
SOLUTIONS AND I'LL HAVE A
RELEASED SOFTWARE TO TRAIN DEEP
NEURAL NETWORKS FOR DETECTION OF
COVID-19 AND THIS IS A PROJECT I
WANT TO TAKE A LITTLE BIT MORE
TIME TO SHARE ABOUT AND THANK
THE NIH FOR AS A SUPPLEMENT TO
MY TRAYS TRAILBLAZER AWARD I WAS
EXCITED ABOUT THE IDEA AND
ASSIST WITH MODIFYING THE TEAM
IN THE HOSPITAL BUT POSSIBLY IN
THE REMOTE LOCATIONS AND
POSSIBLY AT HOME AND BIG SUPPORT
OF THE DATA AND LABELS TO
ENCOURAGE OTHERS TO EXPLORE AND
TO LOWER THE BARRIER TO ENTRY
AND THE IDEAS I HAVE SHARED HAVE
BEEN BROADLY DISSEMINATED TO THE
PUBLIC THROUGH TECHNICAL AND
MEDIA OUTLETS AND A SOURCE OF
EARLIER CAREER FUNDING IN MY LAB
A
AND CHECK OUT THE AND MEDAL
IMAGING TECHNOLOGY AND I'M SO
THRILLED TO SEE THE BIOPHOTONICS
FIELD IS PLACING AN EMPHASIS ON
THIS TOPIC THROUGH THE SPECIAL
ISSUE UPCOMING OF WHICH I'M
GUEST EDITING OF SKIN TONE IN
BIO PHOTONICS ACCEPTING PAPERS
NOW AND THE DEADLINE IS NOVEMBER
15 IF YOU KNOW ANYONE THAT MAY
BE INTERESTED IN SHARING THEIR
WORK TO COALESCE INTO THE ONE
SPECIAL ISSUE.
AND WOULD LIKE TO THANK MY TEAM
AND STUDENTS AND COLLABORATORS
MAKING THE WORK I PRESENTED
POSSIBLE OVER THE YEARS AND
THANKS TO MY GRADUATE ADVISER
WHO STARTED ME ON THIS PATH AND
GRADUATE MENTOR AND MANY MORE
WHO HAVE CONTRIBUTED AND THANK
OTHER PEOPLE I DO WANTS TO GIVE
A NOD TO MY ACADEMIC SISTER IN
THE ROOM, KATHY NIGHTINGALE AND
FUNDING SOURCE TO HELP MAKE THIS
POSSIBLE AND TO PUT SOME FACES
WITH THE NAMES, HERE'S A RECENT
PICTURE OF MY TEAM AND YOU'RE
WELCOME TO VISIT THE POSTLAB FOR
DETAILS AND THANK YOU FOR YOUR
ATTENTION.
>> SO WE HAVE TIME FOR
QUESTIONS.
>> I'LL START.
BISSI, THAT WAS A TERRIFIC TOUR
DE FORCE OF MODALITIES AND HOW
YOU'VE WEAVED SO MANY CONCEPTS
TOGETHER AND DEMONSTRATED THE
POTENTIAL FOR COHERENCE IN THE
CONTEXT OF OVERCOMING SKIN COLOR
CHALLENGES AND PHOTOACOUSTICS.
IT'S REALLY IMPRESSIVE AND
EXCITING.
MY QUESTION OUR CURIOSITY WITH
THE TECHNOLOGIES YOU'RE WORKING
WITH IT STRIKES ME THE USE OF
YOUR TECHNOLOGIES TO DETERMINE
THE LOCATION OF THE ARRAY
ELEMENTS IN THE CONTEXT SEEM TO
HAVE SO MANY OPPORTUNITIES.
IS THERE ONE IN PARTICULAR THAT
YOU'RE GOING TO FOCUS ON OR
BROADER OPPORTUNITY FOR?
>> THE SAME ESTIMATION FOR
ULTRASOUND IMAGING WHICH COULD
POTENTIALLY BE A BIGGER MARKET
AND SOUND SPEED ESTIMATION FOR
THE ENTIRE FIELD.
SOUND SPEED ESTIMATION IS A BIG
CHALLENGE BECAUSE WE ASSUME 1540
METERS PER SECOND IS THE SPEED
OF SOUND IN EVERYBODY'S BODY FOR
EVERY TISSUE AND THAT'S NOT
TRUE.
THE COHERENCE BASED APPROACH TO
ESTIMATION AND THE SAME CONCEPT
CAN GO TO PHOTO ACOUSTIC IMAGING
HAS ULTRASOUND IMAGING AND THOSE
ARE DIRECTIONS MANY I ARE
LOOKING TO EXPLORE DEEPER AND
HAVE EXCITING INNOVATIONS COMING
OUT OF THAT.
>> AMAZING TALK.
I WANT TO FOLLOW UP A LITTLE
BIT.
>> CAN YOU EXTRACT PARTICLES
FROM THIS SITE.
>> WITH THE THEORY MY LAB HAS
DEVELOPED FOR PHOTOACOUSTIC
IMAGING, WE WERE ABLE TO
UNDERSTAND BETTER HOW FREQUENCY
INFLUENCES THE SPATIAL COHERENCE
FUNCTION WE GET AND STILL LOOK
BEING FOR THE APPLICATION TO
APPLY THAT KNOWLEDGE TO SAY THIS
IS WHAT YOU CAN DO WITH IT BUT
WE DO KNOW THERE IS A FREQUENCY
DEPENDENCE AND SHOULD BE
INTERESTING TO DIG DEEPER AND
UNDERSTAND HOW THAT MIGHT IMPACT
BLOOD FLOW OR HOW IMPACT A
VELOCITY BASED APPROACH TO
IMAGING.
ON THE TOPIC OF IMAGING
MECHANICAL PROPERTIES, WE
DEFINITELY ARE ABLE TO --
THERE'S AN ENTIRE FIELD AS I'M
SURE MANY OF YOU KNOW THAT CAN
BENEFIT FROM THE APPROACHES OF
IMAGING AND USING IT TO BETTER
CHARACTERIZE TISSUE AND DIAGNOSE
THESE.
I HAVE NOT SEEN A COMBINATION OF
COHERENCE IMAGING AND ELASTO
GRAPHY THAT'S IMPACTFUL AND MAY
BE AN OPEN AREA FOR
INVESTIGATION IF IT'S POSSIBLE
TO COMBINE IN ANY ONE WAY OR SO.
ON THE TOPIC OF BLOOD FLOW
IMAGING AND DYNAMICS IN THE
BODY.
MY COLLEAGUE JEREMY DAHL HAS
DONE WORK AND I DID WORK
WRAPPING UP MY Ph.D. ON
UNDERSTANDING HOW IT CAN IMPACT
BLOOD FLOW ESTIMATION.
THERE ARE SOME REALLY EXCITING
EXAMPLES FROM THAT WORK AS WELL
AND MAXIMIZING THE SIGNAL TO
NOISE RATIO, IMPROVING IMAGE
QUALITY AND IMPROVING THE
CLARITY OF INFORMATION YOU GET
FROM THESE DYNAMICS AND THEN WE
DON'T WANT TO JUST STOP AT
IMPROVING IT BUT OF COURSE USING
IT TO ENABLE BETTER DIAGNOSIS TO
TREAT DISEASE AND SO I WOULD SAY
THAT IS FOR ME AN OPEN AREA
BECAUSE WE KNOW THAT IT WORKS
BETTER AND NOW WE WANT TO MAKE
AN IMPACT AND SHOW FOR THIS
DISEASE, THIS IS WHAT WE ALREADY
KNOW AS STELLAR PERFORMANCE AND
IMPROVE THE HEALTH CARE SYSTEM.
>> CYNTHIA.
>> THANK YOU SO MUCH.
I LEARNED SO MUCH.
I'M PARTICULARLY CURIOUS TO THE
CARDIAC APPLICATIONS.
I HAVE SOME INTEREST IN CORONARY
IMAGING DO YOU SEE THE
POSSIBILITY OF MAPPING YOU --
MAPPING OUT THE CORONARY PLAQUE
DON'
COMPONENTS.
>> THE COMMUNITY SEEKS TO MAP
OUT ARTERIES AND THE
PHOTOACOUSTIC COMMUNITY HAS
SHOWN IN THE RIGHT EXAMPLE I
GAVE YOU CAN DETECT PLAQUE IN
THE ARTERIES AND I KNOW THERE
ARE OTHER CASES WHERE YOU MIGHT
WANT TO DETERMINE THE THICKNESS
OF THE WALLS AND BLOOD FLOW AND
THE TECHNICAL QUESTIONS.
I WOULD SAY WOULD BENEFIT FROM A
CUSTOMIZED SOLUTION.
PART OF THAT SOLUTION COULD
INCLUDE A COHERENCE-BASED
APPROACH TO IMAGING BUT COULD
ALSO IMPROVE SOMETHING ELSE.
THE ONE COMMON GROUND IS WE NEED
TO DO SOME LEVEL OF SIGNAL ING
TO GET OUTPUT INFORMATION THAT
COULD BE USEFUL FOR THE
APPLICATIONS OF ULTRA SOUND
IMAGING.
IT DOES TAKE A CUSTOMIZED
APPROACH TO UNDERSTAND WHAT IS
NEEDED AND SOME OF THE
TECHNIQUES I SHOWED COULD BE
APPLIED IN THAT CONTEXT AS WELL.
>> SORRY, I'M GOING BACK TO
TECHNICAL AND THE TECHNIQUE OF
MAXIMIZING COHERENCE TO ESTIMATE
YOUR ARRAY SHAPE BUT LINKING
THAT TO WHAT BRUCE WAS TALKING
ABOUT, WOULDN'T IT BE POSSIBLE
ONCE YOU HAVE AN ESTIMATE OF THE
ARRAY SHAPE TO USE COHERENCE TO
FOLLOW CHANGES IN THE SHAPE NOT
OF THE ARRAY BUT SAY CHANGES IN
THE OBJECT?
WOULD YOU -- AND HERE I'M GOING
ON A VERY THIN ANALOGY WITH MRI
STUFF THAT HAS BEEN DONE,
MOTION-GUIDED IMAGE
RECONSTRUCTION FOR EXAMPLE WHERE
YOU MAXIMIZE SPARSITY IN ORDER
TO ESSENTIALLY YOU FOLLOW HOW
THE IMAGE IS CHANGING BECAUSE
YOU HAVE SOME ASSUMPTION THE
MOST SPARSE SOLUTION IS THE BEST
AND IT SEEMS TO ME YOU'RE DOING
SOMETHING SIMILAR.
COULD YOU USE THIS NOT JUST TO
ESTIMATE THE ARRAY SHAPE BUT
ESTIMATE MOTION?
BOOT STRAP YOUR WAY?
>> THAT'S AN EXCITING WAY AND
CONCEPT AND NEVER THOUGHT ABOUT
IT THAT WAY BEFORE BUT IF YOU
COULD ESTIMATE THE ARRAY SHAPE.
I WOULD SAY THE APPROACH OF
ESTIMATING VELOCITY DOES REQUIRE
KNOWLEDGE OF THE ARRAY SHAPE
BECAUSE WE DON'T WANT TO CREATE
A PROBLEM ESTIMATING ALL THESE
DIFFERENT THINGS.
IF YOU KNOW THE ARRAY SHAPE OR
ARE SATISFIED THEN YOU COULD
POTENTIALLY TURN THE ESTIMATION
PROBLEM INTO WHERE IS MY TAR
GUEST -- TARGET AND IT'S
POSSIBLE AND HOW TO IMPLEMENT I
HAVE TO THINK MORE DEEPLY ABOUT
AND GREAT QUESTION AND POSSIBLY
EXCITING AREA TO PURSUE.
THANK YOU.
>> THAT WAS REALLY BEAUTIFUL.
THANK YOU SO MUCH.
SO I HAD A QUESTION FOR YOU I
GUESS TWO EXAMPLES YOU SHOWED
WHERE THE DIFFERENCE BETWEEN THE
COHERENCE BETWEEN FLUID AND I
THINK METHYLENE AND HEMOGLOBIN
AND LOOKING AT NOT JUST COLLAGEN
FOR THE MOLECULAR SIDE OR DO YOU
FEEL IT NEEDS TO BE COUPLED WITH
MOLECULAR CONTRAST AGENTS?
I WONDER WHAT YOUR THOUGHTS ARE
ON THE COMBINATION OF THOSE OR
WHAT THE POSSIBILITIES ARE,
CONTRAST FREE.
>> I THINK THERE'S A WHOLE WORLD
TO EXPLORE IN THAT AREA.
FOR SURE IF WE'RE GOING TO THE
MOLECULAR SCALE WE WANT TO MAKE
SURE OUR FREQUENCIES OF IMAGING
SYSTEMS ARE MATCHED AND WANT TO
GO WITH THEE HIGHER FREQUENCY
SYSTEMS TO SEE POTENTIALLY
MOLECULAR LEVEL INFORMATION.
I ALSO THINK THAT THE MOLECULAR
INFORMING CAN BE IN OPTICAL
ABSORPTION SPECTRA.
IF THAT DOESN'T EXIST YET THE
FIRST STEP WOULD BE TO CREATE
THAT KNOWLEDGE.
ONCE WE CREATE IT AND
INFORMATION WHAT THE LINKAGE
MIGHT BE, THEN WE'D BE IN A
BETTER POSITION TO DEVELOP NEW
TECHNOLOGY TO TAKE ADVANTAGE OF
THAT LINKAGE.
AND SO I'M NOT TOO WELL VERSED
IN THE COLLAGEN LITERATURE BUT
IF FOR EXAMPLE COLLAGEN HAS A
DIFFERENT OPTICAL ABSORPTION
STRUCTURE AND SOMETHING ELSE
YOU'RE TRYING TO DISTINGUISH
BETWEEN WE CAN MOVE TO THE STEP
OF HOW TO USE THE KNOWLEDGE AND
IF IT'S NOT YET KNOWN OR IF IT'S
REPORTED AS NOT EXISTENT I WOULD
TAKE THE APPROACH OF VERIFYING
THAT'S TRUE BECAUSE IN MY LAB WE
HAVE SEEN CASES WHERE WE READ
LITERATURE AND DON'T SEE THERE'S
AN OBVIOUS SPECTRAL INFORMATION
IN SOME TISSUE OF INTEREST AND
THEN PERFORM THE EXPERIMENT AND
FIND OUT WHILE THERE'S NO
LINKAGE TO ONE PARTICULAR
COMPONENT, MAYBE THE COMBINATION
OF COMPONENTS GIVE A UNIQUE
SPECTRAL SIGNATURE AND THAT
COULD BE A SOURCE OF INFORMATION
TO THEN CAPITALIZE ON TO CREATE
NEW INNOVATIONS.
>> TO FOLLOW UP ON THAT YOU
MENTIONED IN YOUR SIMULATION YOU
WERE ABLE TO REMOVE THE SKIN.
>> YES.
>> I WONDER IF YOU CAN
SPECTRALLY IF IT'S MELANIN,
COULD YOU THEN TARGET AND
SUBTRACT OUT BECAUSE MELANIN HAS
A UNIQUE SPECTRAL SIGNATURE.
ARE YOU DOING THAT?
WOULD THAT BE POSSIBLE?
>> THAT WOULD BE POSSIBLE BUT
PROBABLY WITH A DIFFERENT MODEL
FROM THE ONE WE'RE USING BECAUSE
THE MODEL WE'RE USING AVERAGES
THE DIFFERENT TISSUES IN SKIN
AND SAYS THIS IS THE OPTICAL
ABSORPTION OF SKIN WITH
THICKNESS AND SKIN TONE AND
OTHER MODELS SAY SKIN HAS
MELANIN, IT HAS BLOOD, IT HAS
FAT AND THESE ARE THE DIFFERENT
OPTICAL PROPERTIES OF THE
DIFFERENT CONSTITUENTS AND CAN
UNDERSTAND HOW IT EXTRACTS THE
SPECTERAL FEATURES AND THERE'S A
LOT TO PLAY WITH IN THAT AREA
TOO.RAL FEATURES AND THERE'S A
LOT TO PLAY WITH IN THAT AREA
TOO.IRAL FEATURES AND THERE'S A
LOT TO PLAY WITH IN THAT AREA
TOO.RAL FEATURES AND THERE'S A
LOT TO PLAY WITH IN THAT AREA
TOO.ORAL FEATURES AND THERE'S A
LOT TO PLAY WITH IN THAT AREA
TOO.
>> ARE YOU WORKING WITH PEOPLE
USING HYPERTHEMIA AND A PROBLEM
IS HOW ACCURATE IT GETS TO AVOID
COMPLICATIONS BUT IT WOULD SEEM
LIKE THE TECHNOLOGY YOU HAVE
WOULD BE A GREAT COMPANION.
>> I WOULD LOVE TO BE CONNECTED
WITH THOSE PEOPLE.
I'M NOT CURRENTLY WORKING IN
THAT AREA BUT WOULD LOVE TO
EXPLORE WHAT THE POSSIBILITIES
COULD BE AND HOW THE TECHNOLOGY
COULD BE USED IN THAT DOMAIN.
THANK YOU.
OKAY.
LET'S CONNECT.
>> BEAUTIFUL WORK.
SO EXCITING TO SEE EVERYTHING
YOU'VE ACCOMPLISHED.
THIS IS NOT A TECHNICAL QUESTION
BUT ONE THING I NOTICED AND IS
STRIKING IS THAT IN YOUR
COLLABORATION YOU HAVE SO MANY
M.D.s AND HAVE SHOWN THE THEORY
TO CLINIC AND IN THINKING ABOUT
YOUR TRAINING, WHETHER THAT WAS
A GRADUATE STUDENT OR POSTDOC
WAS THERE ANYTHING YOU LEARNED
HOW TO CREATE THOSE SUCCESSFUL
PARTNERSHIPS AND COLLABORATIONS
BECAUSE IT IS SOMETHING ELEVATED
AND TAKING YOUR WORK TO THE NEXT
LEVEL.
>> THANK YOU FOR THE QUESTION.
LET ME THINK.
I THINK A LOT OF THE TRAINING
PREPARED ME.
SOME I TOOK FOR GRANTED.
ANOTHER PLUG TO THE NIH.
I WAS OWN A TRAINING GRANT AS A
GRADUATE STUDENT AND THROUGH
THAT I GOT EXPOSURE TO DIFFERENT
MEDICAL IMAGING TECHNIQUES AND
WHILE I ALWAYS HAD IN INTEREST
IN ULTRASOUND IT WAS INTERESTING
TO SEE THE OTHER LABS AND
NUCLEAR MEDICINE IMAGING AND
WORK WITH THE DATA AS A MEMBER
OF THE TRAINING GRANT AND USE
THAT INFORMATION TO UNDERSTAND
HOW OTHER TECHNIQUES WORK.
AND I ALSO HAD THE OPPORTUNITY
TO BUILD SYSTEMS BUT TAKE THEM
TO THE HOSPITAL AS A GRADUATE
STUDENT.
AND THAT IS AN EXPERIENCE THAT I
REALIZE NOT EVERYONE HAS AND
PROBABLY ANOTHER ONE OF THOSE
THINGS I TOOK FOR GRANTED AT THE
TIME AS I BECAME AN ASSISTANT
PREVENTION IN TRYING TO FORM THE
SIMILAR RECREATE THE EXPERIENCE,
I GET DIFFERENT LEVELS OF
INTEREST IN COLLABORATIONS.
SO I HAVE STUDENTS THAT COME TO
ME -- I GUESS IT LOOKS
EFFORTLESS SO THEY SAY I WANT TO
START LOOKING AT PANCREAS
IMAGING AND I SAY FIRST WE HAVE
TO RESPOND TO SOMEONE AND THEY
HAVE TO BE INTERESTED IN WORKING
WITH ME AND IT'S NOT AS SIMPLE
AS IT SEEMS OR AS I MIGHT HAVE
THOUGHT IT WAS AS A GRADUATE
STUDENT BECAUSE WHAT I DIDN'T
REALIZE WAS A LOT OF THE LEG
WORK MY ADVISER HAD PUT INTO
BUILDING THE RELATIONSHIPS TO
MAKE IT SEAMLESS FOR ME, I THINK
THAT WAS ALSO JUST HAVING THE
IMPRESSION THAT, YES, OF COURSE
DOCTORS WANT TO WORK WITH
ENGINEERS, NO QUESTION.
TAKING THAT APPROACH OF NOT
BEING SHY TO ASK PEOPLE AND
ASSUME THEY WANT TO USE MY
TECHNOLOGY AND OF COURSE THEY
WANT TO MAKE THE WORLD A BETTER
PLACE BUT SOME M.D.s JUST WANT
TO TREAT PATIENTS WITH THE
TECHNOLOGY THAT EXISTS AT
HOPKINS MORE PEOPLE WANT TO WORK
WITH THE ENGINEERS AND BEING IN
THAT VARIETY HELPS FUEL THE
COLLABORATIONS AS WELL.
>> FANTASTIC PRESENTATION.
I WANT TO TAKE CREDIT FOR THE
NSFEEC PROGRAM AND I HAVE A LOT
OF TECHNICAL QUESTIONS WE CAN
MAYBE TALK ABOUT LATER IN THE
OPTICAL SIDE BUT WITH THE
SUPERIORITY OF THE TECHNOLOGY
FOR FLUOROSCOPY IS MIND BLOWING.
DO YOU HAVE REGULATORY
CHALLENGES?
>> LOTS OF THEM FOR SURE.
HELP ME, PLEASE.
I SEE REGULATORY CHALLENGES AS
ONE OF THE BIGGEST BARRIERS TO
TRANSLATING THE TECHNOLOGY TO
THE CLINIC.
ESPECIALLY GOING WITH THE
INTERVENTIONAL APPLICATIONS.
IT'S NO LONGER NON-INVASIVE.
IT'S MINIMALLY INVASIVE AND
THERE'S STERILIZATION PROTOCOLS
WE HAVE TO FOLLOW AND STILL
PRODUCING THE DATA TO SHOW RIGOR
AND REPRODUCIBILITY WHETHER OR
NOT IT'S INVASIVE AND THE
ADDITIONAL COMPONENT OF CROSSING
THE MUCOSAL BARRIER DOES ADD ON
ANOTHER PLAYER OF THE ALREADY I
WOULD SAY CHALLENGING OF GETTING
REGULATORY APPROVAL AND SO THAT
IS SOMETHING THAT I THINK
REQUIRES DEDICATED PERSONNEL WHO
UNDERSTAND THE CHALLENGES WHO
MAY HAVE GONE THROUGH IT BEFORE
AND IN A POSITION TO ADVISE.
THIS IS HOW THESE EXPERIMENTS
SHOULD BE SET UP FROM EARLY ON
SO YOU DON'T HAVE TO REDO THE
EXPERIMENTS TO MEET STANDARDS.
THOSE ARE A FEW OF THE THINGS I
HAVE BEEN THINKING ABOUT FROM
THE REGULATORY PERSPECTIVE.
>> THE MOMENT HAS COME.
YOU'RE GOING TO TAKE SOMETHING
HOME.
>> OKAY.
>> THIS IS YOUR PLAQUE IN
COMMEMORATION TO YOUR EXCELLENT
LECTURE TO ADD ON TO OUR
EXCITING ANSWER FOR REGULATORY,
DON'T FORGET ABOUT THE A.I. PART
BUT LOTS OF ALGORITHMS HAVE BEEN
APPROVED, 882 AS WE LAST TALKED
ABOUT BY THE FDA.
IT'S I MOVING TARGET AND YOU CAN
LEAD IN THIS AREA SO
CONGRATULATIONS AND THANK YOU SO
MUCH FOR YOUR LECTURE.
>> THANK YOU.
>> THANKS TO EVERYONE.
WE HAVE A BREAK FOR LUNCH NOW.
>> THANK YOU, BRUCE.
LET'S HAVE AN ABBREVIATED LUNCH.
WE TOOK ADVANTAGE TO SPEND THE
TIME IN OPEN SESSION SO LET'S
COME BACK AT 2:20.
I KNOW IT'S ABBREVIATED, 2:20
P.M.
WE'LL HAVE THE LUNCH IS ACROSS
THE HALL BUT THE PLACE WE'RE
EATING IS ACROSS THE BUILDING ON
THE OTHER SIDE OF THE LOBBY.
FOR COLLEAGUES ATTENDING CLOSED
SESSION IN PERSON, THERE'LL BE A
SIGN UP SHEET.
FOR THOSE RUNNING HOME AND MAY
PARTS OPERATE ON ZOOM WE'LL GET
YOUR ATTENDANCE.
THANK YOU FOR YOUR ATTENDING.
WE HOPE YOU CAN ATTEND THE NEXT
COUNCIL MEETING AND THIS OPEN
SESSION OF THE 66th MEETING OF
THE NIBIB ADVISORY COUNCIL IS
HEREBY ADJOURNED.