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GOOD MORNING AND WELCOME.

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I WOULD LIKE TO CALL TO ORDER

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THE 63rd MEETING OF THE NIH

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ADVISORY COMMITTEE ON RESEARCH

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ON WOMEN'S HEALTH.

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MY NAME IS VIVIAN OTA WANG AND

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I'M THE ACTING DIRECTOR OF THE

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OFFICE OF STRATEGIC COORDINATION

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ON DETAIL FROM ORWH AND THE

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DEPUTY DIRECTOR OF THE OFFICE OF

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RESEARCH ON WOMEN'S HEALTH.

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THIS MEETING IS OPEN TO THE

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PUBLIC, VIA LIVE BROADCAST ON

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THE NIH VIDEO NETWORK AND IT'S

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BEING RECORDED FOR OUR ARCHIVES

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AND FOR FUTURE ON DEMAND VIEWING

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BY THE PUBLIC.

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NEXT SLIDE, PLEASE.

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IF YOU ARE A MEMBER OF THE

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PUBLIC, PER THE FEDERAL REGISTER

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NOTICE, YOU MAY SUBMIT QUESTIONS

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IN WRITING TO ME AT A

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CRWH@NIH.GOV AS YOU CAN SEE ON

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THE SCREEN AND WE WILL ADDRESS

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QUESTIONS AFTER THE MEETING.

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NEXT SLIDE, PLEASE.

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THIS MEETING IS VIRTUAL ISSUE

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THE ADVISORY COMMITTEE AND OUR

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INVITED GUEST PRESENTERS ARE

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PARTICIPATING THROUGH TEAMS.

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NOW A MESSAGE TO OUR MEMBERS AND

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THIS IS A REMINDER BECAUSE

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YOU'RE SPECIAL GOVERNMENT

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EMPLOYEES.

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AS MEMBERS OF THIS FEDERAL

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ADVISORY COMMITTEE, YOU ARE A

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SPECIAL GOVERNMENT EMPLOYEES,

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WHICH MEANS YOU ARE SUBJECT TO

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THE SAME ETHICS RULES THAT APPLY

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TO GOVERNMENT EMPLOYEES, THESE

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RULES ARE DESCRIBED IN THE

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PAMPHLET TITLED STANDARDS OF

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ETHICAL CONDUCT FOR EMPLOYEES OF

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THE EXECUTIVE BRANCH.

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YOU RECEIVED A COPY OF THIS

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DOCUMENT WHEN YOU WERE

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APPOINTED.

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AT EVERY MEETING WE WOULD LIKE

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TO REVIEW THE STEPS WE TAKE AND

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THE PROCESS WE FOLLOW TO

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IDENTIFY AND ADDRESS ANY

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CONFLICTS BETWEEN YOUR PUBLIC

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RESPONSIBILITIES AND YOUR

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PRIVATE INTERESTS.

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AS YOU KNOW BEFORE EACH MEETING

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YOU PROVIDE US WITH A GREAT DEAL

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OF INFORMATION ABOUT YOUR

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PROFESSIONAL AND PERSONAL

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FINANCIAL INTEREST MPLET WE USE

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THIS INFORMATION AS A FOUNDATION

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FOR ASSESSING WHETHER YOU HAVE

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ANY REAL, POTENTIAL OR APPARENT

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CONFLICTS OF INTEREST THAT COULD

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COMPROMISE YOUR ABILITY TO BE

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OBJECT  IN GIVING ADVICE DURING

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OUR COMMITTEE MEETINGS.

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IF THE NEED FOR YOUR INDIVIDUAL

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SERVICE OUTWEIGHS THE POTENTIAL

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CONFLICTS OF INTEREST THAT WE'VE

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IDENTIFIED WE WOULD ISSUE A

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WAIVER OR RECUSE YOU FROM A

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PARTICULAR PORTION OF THE

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MEETING.

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WE USUALLY WAVE CONFLICTS OF

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INTEREST FOR GENERAL MATTERS

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BECAUSE WE BELIEVE YOUR ABILITY

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TO BE OBJECTIVE WILL NOT BE

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AFFECTED BY YOUR FINANCIAL

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INTERESTS.

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WE ALSO RELY A GREAT DEAL ON

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YOU.

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YOU NEED TO BE ATTENTIVE DID   O

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MEETINGS TO AN ISSUE THAT COULD

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ARISE TO EFFECTOR APPEAR TO

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EFFECT WITH RESPONSE TO YOUR

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SPECIFIC PARTY OR MATTER IN THIS

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HAPPENS.

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AND IF DOES HAPPEN, YOU WILL BE

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ASKED TO RECUSE YOURSELF FROM

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THAT PORTION OF THE MEETING.

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NEXT SLIDE, PLEASE.

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BEFORE INTRODUCTIONS, I JUST

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BRIEFLY WANT TO REVIEW BEST

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PRACTICES FOR OUR PARTICIPANTS

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IN THIS VIRTUAL SETTING.

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FIRST IF YOU COULD PLEASE MUTE

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YOUR MICROPHONE IN YOU'RE NOT

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SPEAKING.

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SECOND IF YOU COULD TRY TO USE A

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HEAD SET WITH A MICROPHONE WHEN

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SPEAKING THAT REALLY DOES RESULT

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IN THE CLEAREST SOUND AND

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PROVIDE THE LEAST AMOUNT OF

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AUDIO FEEDBACK.

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WHEN SPEAKING PLEASE STAYED YOUR

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NAME BEFORE MAKING COMMENTS,

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MOTIONS OR RECOMMENDATIONS, AND

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LASTLY RAISE YOUR HAND FEATURE

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OR ENTER YOUR COMMENT OR

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QUESTION DIRECTLY INTO THE CHAT

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BOX.

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NEXT SLIDE, PLEASE EMPLOY AS I

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GO THROUGH THE ROSTER WHEN YOU

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HEAR YOUR NAME, UNMUTE YOUR

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AMERICA IC AND INTRODUCE

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YOURSELF BY WHAT NAME AND

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INSTITUTIONS YOU REPRESENT. 

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DR. ANDERSON?

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>> GOOD MORNING DR.
ANDERSON

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FROM THE FRED HUTCHISON CANCER

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CENTER.

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>> DR. ANUNYA,.

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>> GOOD MORNING I'M WITH
THE

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ASSOCIATE FOR WOMEN'S HEALTH

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RESEARCH.

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>> GOOD MORNING, DR.
ARNOLD?

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>> MORNING, I'M ART ARNOLD
AT

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THE UNIVERSITY OF CALIFORNIA

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LOS ANGELES. 

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DR. BREWER?

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OKAY, WE'LL MOVE ON, DR. GIDDY?

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>> GOOD MORNING, DR. GIDDY
FROM

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VANDERBILT UNIVERSITY MEDICAL

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CENTER.

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>> THANK YOU GOOD MORNING.

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DR. HIGGINS?

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>> GOOD MORNING STEVE
HIGGINS

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FROM THE UNIVERSITY OF VERMONT.

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>> THANK YOU, GOOD
MORNING.

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DR. JONES?

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>> GOOD MORNING DR.
ANDRIEA

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JONES FROM THE UNIVERSITY OF

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NORTH CAROLINA AT CHAPEL HILL.

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>> THANK YOU, GOOD
MORNING,

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DR. FEISTER?

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OKAY, MOVING ON DR. MELANDS?

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>> YES, GOOD MORNING FROM

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COLUMBIA UNIVERSITY, SCHOOL OF

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PUBLIC HEALTH.

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>> GOOD MORNING DR. NOEL?

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>> GOOD MORNING, I AM
ALEXANDRA

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NOEL FROM LOUISIANA STATE

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UNIVERSITY.

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>> THANK YOU AND GOOD
MORNING. 

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>> DR. OFUTOCUN. 

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AND DR. SHARPS?

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OKAY, NEXT SLIDE, PLEASE.

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YOU WERE EACH SENT THE MINUTES

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FROM OUR LAST MEETINGS THAT WERE

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HELD ON ACT EIGHTH AND

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DECEMBER 9th FOR REVIEW.

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I WANT TO NOTE THAT ONLY FULL

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MEMBERS OF THE ADVISORY

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COMMITTEE MAY VOTE AND YOU ARE

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NOT A MEMBER OF ACRWH, PLEASE DO

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NOT VOTE.

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IS THERE A MOTION ON THE TABLE

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TO ACCEPT THE OCTOBER, EIGHTH,

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AS WRITTEN?

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>> I HAVE A MOTION.

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>> THANK YOU, DO I HEAR A

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SECOND? 

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>> I'LL SECOND.

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-- I'LL SECOND THE MOTION, STEVE

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HIGGINS.

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>> THANK YOU DR. HIGGINS,

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DR. HIGGINS HAS SECONDED THE

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MOTION, ALL IN FAVOR OF

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ACCEPTING THE MOTION PLEASE

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RAISE YOUR HANDS NOW.

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ALL THOSE OPPOSE TO THE MOTION,

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CAN YOU PLEASE RAISE YOUR HANDS

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NOW, THANK YOU.

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ALL THOSE ABSTAINING FROM THE

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MOTION, PLEASE RAISE YOUR HANDS

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NOW.

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THANK YOU VERY MUCH.

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HAVE THE VOTES BEEN RECORDED?

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>> YES, THE VOTES HAVE
BEEN

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RECORDED, WE HAVE 7 VOTES IN

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FAVOR.

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>> THANK YOU.

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THE OCTOBER 8th 2024 MEETING

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MINUTES HAVE BEEN ACCEPTED WITH

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7 VOTES IN FAVOR.

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OKAY, IS THERE A MOTION ON THE

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TABLE TO ACCEPT THE

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DECEMBER 9th, 2024 MINUTES AS

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WRITTEN IN?

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>> I'LL MAKE A MOTION,
STEVE

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HIGGINS.

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>> THANK YOU DR. HIGGINS.

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DR. HIGGINS SUBMITTED THE

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MOTION, DO I HEAR A SECOND?

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>> DR. MELANDS, I WILL

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SECURITIZATION. THE MOTION.

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>> THANK YOU DR. MELLANDS,

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DR. MELANDROGENS HAS SECONDED

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THE MOTION, ALL IN FEAEVER OF

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ACCEPTING THE MOTION, PLEASE

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RAISE YOUR HANDS NOW.

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THANK YOU.

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ALL OF THOSE OPPOSE TO THE

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MOTION, CAN YOU PLEASE RAISE

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YOUR HANDS NOW? 

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AND ALL THOSE ABSTAINING FROM

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MOTION, PLEASE RAISE YOUR HANDS

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NOW.

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THANK YOU HAVE THE VOTES BEEN

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RECORDED?

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>> YES, THE VOTES HAVE
BEEN

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RECORDED, WE HAD 8 VOTES IN

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FAVOR.

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>> THE DECEMBER 9th, 2024

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MEETING MINUTES HAVE BEEN

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ACCEPTED WITH 9 VOTES IN FAVOR. 

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NEXT SLIDE, PLEASE.

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AS AN ORWH UPDATE, I AM TRULY

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HAPPY TO SHARE THAT DURING

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OCTOBER OF LAST YEAR, THE ORWH

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DIRECTOR DR. JANINE CLAYTON WAS

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ELECTED TO THE NATIONAL ACADEMY

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OF MEDICINE.

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CONGRATULATIONS DR. CLAYTON,

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WITH THIS I CONCLUDE MY OPENING

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REMARKS AND INTRODUCE THE CHAIR

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OF THE COMMITTEE DR. JANINE,

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CLAYTON.

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SOME, THANK YOU SO MUCH

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DR. WANG, AND THANK YOU FOR

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THOSE WARM CONGRATULATEARY

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REMARKS AS WELL AND I ROLELY

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APPRECIATE DR. OTA WANG FOR

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PARTICIPATING TODAY, YOU WILL

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HEAR MORE ABOUT WHAT SHE'S DOING

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BUT THANK YOU SO MUCH VIVIAN FOR

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BEING WITH US TODAY.

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IT'S NOW MY PLEASURE TO

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INTRODUCE DR. NICOLE

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KLEINSTREUER, HE IS THE NIH

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ACTING DEPUTY DIRECTOR FOR

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PROGRAM COORDINATION, PLANNING,

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STRATEGIC INITIATIVES, AND

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FONDLY KNOWN AS DPC PSI WITHIN

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THE OFFICE OF THE NIESHES H

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DIRECTOR.

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SHE OVERSEES, ALL OF THE

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INFORMATION AND RESEARCH ON THE

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WOMEN'S HEALTH, OTHER OFFICE

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SPOKEUS ON AIDS RESEARCH,

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00:10:36,925 --> 00:10:39,461
BEHAVIORIAL AND SOCIAL SCIENCES,

262
00:10:39,461 --> 00:10:41,463
DIETARY SUMMIT LEPS, TRIBAL

263
00:10:41,463 --> 00:10:41,963
HEALTH AND OTHERS.

264
00:10:41,963 --> 00:10:46,835
I WANT TO INTRODUCE YOU TO

265
00:10:46,835 --> 00:10:48,803
DR. KLEINSTREUER, WHO IS AN

266
00:10:48,803 --> 00:10:50,639
INTERNATIONAL RECOGNIZED EXPERT

267
00:10:50,639 --> 00:10:52,307
ON DEVELOPING HUMAN RELATED

268
00:10:52,307 --> 00:10:53,708
PUBLIC HELT STRATEGIES FOR

269
00:10:53,708 --> 00:10:54,442
PUBLIC HEALTH PROTECTION.

270
00:10:54,442 --> 00:10:56,244
PRIOR TO HER CURRENT POSITION

271
00:10:56,244 --> 00:10:57,879
SHE SERVED AS THE NATIONAL

272
00:10:57,879 --> 00:10:58,913
DIRECTOR OF THE TOXICOLOGY

273
00:10:58,913 --> 00:11:00,782
PROGRAM IN THE AGENCY CENTER FOR

274
00:11:00,782 --> 00:11:04,819
THE EVALUATION OF ALTERNATIVE

275
00:11:04,819 --> 00:11:06,588
TOXICOLOGICAL METHODS, NICETEM,

276
00:11:06,588 --> 00:11:09,958
WITHIN THE NIEHS, AND ALSO

277
00:11:09,958 --> 00:11:12,460
SERVICE'RE SERVED AS DIRECTOR OF

278
00:11:12,460 --> 00:11:13,194
THE INTERAGENCY COORDINATING

279
00:11:13,194 --> 00:11:18,033
COMMITTEE ON THE VALIDATION OF

280
00:11:18,033 --> 00:11:18,633
ALTERNATIVE METHODS, ICVAM.

281
00:11:18,633 --> 00:11:24,072
SHE WAS ALSO THE NATIONAL

282
00:11:24,072 --> 00:11:26,041
COORDINATOR THE OECD TEST

283
00:11:26,041 --> 00:11:28,476
GUIDELINES PROGRAMS AND SHE'S

284
00:11:28,476 --> 00:11:30,478
LED INTERNATIONAL EFFORTS FOR

285
00:11:30,478 --> 00:11:31,980
NIAMS, REDUCE ANIMAL TESTING AND

286
00:11:31,980 --> 00:11:40,088
EPITHELIAL GREAT  COMPUTATIONAL

287
00:11:40,088 --> 00:11:41,623
MODELING, INTEGRATIVE SYSTEMS

288
00:11:41,623 --> 00:11:42,524
AND REGULATORY SCIENCE.

289
00:11:42,524 --> 00:11:45,293
HER WORK HAS WORKED ON QUANT

290
00:11:45,293 --> 00:11:46,761
TAIFIVE RISK ASSESSMENT AND

291
00:11:46,761 --> 00:11:49,297
AUTHORED OVER 150 PEER REVIEWED

292
00:11:49,297 --> 00:11:51,800
PUBLICATIONS RECEIVING NUMEROUS

293
00:11:51,800 --> 00:11:52,767
AWARDS INCLUDING THE 2019

294
00:11:52,767 --> 00:11:54,135
SOCIETY OF TOXICOLOGY

295
00:11:54,135 --> 00:11:57,005
ACHIEVEMENT AWARD AND A 2025

296
00:11:57,005 --> 00:11:57,939
ENHANCEMENT OF ANIMAL WELFARE

297
00:11:57,939 --> 00:12:02,844
AWARD AS WELL AS MULTIPLE NIH

298
00:12:02,844 --> 00:12:06,147
DIRECTORS AND NIEHS MERIT

299
00:12:06,147 --> 00:12:06,381
AWARDS.

300
00:12:06,381 --> 00:12:08,049
TO SAY MORE ABOUT HER

301
00:12:08,049 --> 00:12:11,219
BACKGROUND, SHE HOLDS DEAGREES

302
00:12:11,219 --> 00:12:13,488
IN APPLIED PATH MATHICS AND A

303
00:12:13,488 --> 00:12:14,856
Ph.D. IN BIOENGINEERING FROM

304
00:12:14,856 --> 00:12:16,858
THE UNIVERSITY OF CANTERBURY AND

305
00:12:16,858 --> 00:12:19,728
COMPLETED POST DOCS AT THE EPA

306
00:12:19,728 --> 00:12:22,063
AND HAS ADJUNCT FACULTY

307
00:12:22,063 --> 00:12:22,864
APPOINTMENTS, IMPORTANTLY SHE'S

308
00:12:22,864 --> 00:12:24,833
DEEPLY COMMITTED TO MENTORSHIP,

309
00:12:24,833 --> 00:12:26,334
PUBLIC HEALTH PROTECTION AND

310
00:12:26,334 --> 00:12:27,035
SCIENTIFIC INNOVATION THAT

311
00:12:27,035 --> 00:12:29,070
ENHANCE THE TRANSLATION OF

312
00:12:29,070 --> 00:12:31,005
BIOMEDICAL RESEARCH TO WORK REAL

313
00:12:31,005 --> 00:12:32,974
WORLD IMPACT AND IT'S OUR

314
00:12:32,974 --> 00:12:37,011
PLEASURE TO WELCOME HER HERE

315
00:12:37,011 --> 00:12:40,849
TODAY.

316
00:12:40,849 --> 00:12:41,416
DR. KLEINSTREUER.

317
00:12:41,416 --> 00:12:42,484
>> THANK YOU SO MUCH.

318
00:12:42,484 --> 00:12:43,518
IT'S A REAL PLEASURE TO I DIDN'T

319
00:12:43,518 --> 00:12:45,386
EVEN YOU TODAY FOR THIS 63rd

320
00:12:45,386 --> 00:12:49,124
MEETING OF THE NIH ADVISORY

321
00:12:49,124 --> 00:12:51,126
COMMITTEE ON RESEARCH ON WOMEN'S

322
00:12:51,126 --> 00:12:51,359
HEALTH.

323
00:12:51,359 --> 00:12:52,527
REALLY DELIGHTED TO BE HERE

324
00:12:52,527 --> 00:12:53,495
SPEAKING TO YOU ALL.

325
00:12:53,495 --> 00:12:56,464
OKAY, I THINK I SHOULD BE ABLE

326
00:12:56,464 --> 00:12:57,766
TO TAKE CONTROL, HERE WE GO.

327
00:12:57,766 --> 00:13:03,438
SO I CAN ADVANCE MY OWN SLIDES

328
00:13:03,438 --> 00:13:04,239
AND LET'S SEE.

329
00:13:04,239 --> 00:13:06,040
THERE WE GO.

330
00:13:06,040 --> 00:13:06,508
OKAY.

331
00:13:06,508 --> 00:13:08,476
AS DR. CLAYTON MENTIONED, I AM

332
00:13:08,476 --> 00:13:12,247
THE ACTING NIH DEPUTY DIRECTOR

333
00:13:12,247 --> 00:13:14,282
FOR PROGRAM PLANNING

334
00:13:14,282 --> 00:13:15,650
COORDINATION AND STRATEGIC

335
00:13:15,650 --> 00:13:18,419
INITIATIVES AS WELL AS ACTING

336
00:13:18,419 --> 00:13:21,689
DIRECTOR OF DPC PSI AT NIH, NIH

337
00:13:21,689 --> 00:13:23,992
IS MADE UP OF 27 INSTITUTES AND

338
00:13:23,992 --> 00:13:25,193
CENTERS WITH EXCEPTION OF THE

339
00:13:25,193 --> 00:13:29,097
OFFICE OF THE DIRECTOR WHERE DPC

340
00:13:29,097 --> 00:13:30,532
PSI IS HOUSED AND WHERE THE

341
00:13:30,532 --> 00:13:32,033
OFFICE OF WOMEN'S HEALTH

342
00:13:32,033 --> 00:13:34,869
RESEARCH RESIDES WITHIN THIS

343
00:13:34,869 --> 00:13:37,505
DIVISION, SO WHAT DOES DPC PSI

344
00:13:37,505 --> 00:13:39,274
DO, WE ARE THE HOME FOR

345
00:13:39,274 --> 00:13:40,208
COORDINATION, PLANNING WITHIN

346
00:13:40,208 --> 00:13:41,176
THE OFFICE OF THE DIRECTOR AND I

347
00:13:41,176 --> 00:13:43,044
THINK WE ARE INCREDIBLE LOAMACYY

348
00:13:43,044 --> 00:13:45,547
WELL POISED TO ADDRESS EACH OF

349
00:13:45,547 --> 00:13:47,382
THOSE NEEDS AND ACTIVITIES

350
00:13:47,382 --> 00:13:50,118
ACROSS THE NIH AND I WOULD LIKE

351
00:13:50,118 --> 00:13:54,656
TO THINK OF DPC PSI AS THE

352
00:13:54,656 --> 00:13:57,192
SCIENTIFIC NEXUS OF THE NIH AND

353
00:13:57,192 --> 00:14:01,329
OUR OFFICES HAVE MANY ROLES BUT

354
00:14:01,329 --> 00:14:03,231
ORWHH IS A PERFECT EXAMPLE OF AN

355
00:14:03,231 --> 00:14:04,833
OFFICE THAT ADDRESSES A CROSS

356
00:14:04,833 --> 00:14:05,667
CUTTING RESEARCH THEME THAT MANY

357
00:14:05,667 --> 00:14:08,937
IF NOT ALL OF THE ICs ARE

358
00:14:08,937 --> 00:14:10,905
HEAVILY ENGAGED IN.

359
00:14:10,905 --> 00:14:13,908
SO DPC SI IS REALLY TO IDENTIFY

360
00:14:13,908 --> 00:14:15,410
AND CATALOG THAT RESEARCH TO

361
00:14:15,410 --> 00:14:17,045
IDENTIFY SCIENTIFIC GAPS AND

362
00:14:17,045 --> 00:14:18,213
OPPORTUNITIES, FOSTER

363
00:14:18,213 --> 00:14:19,347
COORDINATION AND COLLABORATION,

364
00:14:19,347 --> 00:14:21,249
ACROSS THE DIFFERENT ICs,

365
00:14:21,249 --> 00:14:25,019
DEVELOP NEW METHODS TO ADDRESS

366
00:14:25,019 --> 00:14:26,521
THOSE RESEARCH GOALS AND ENABLE

367
00:14:26,521 --> 00:14:29,324
THEM AND TO SORT OF SERVE AS AN

368
00:14:29,324 --> 00:14:31,092
EXPERIMENTAL TEST BED FOR

369
00:14:31,092 --> 00:14:32,794
INNOVATIVE AND HIGHLY INNOVATIVE

370
00:14:32,794 --> 00:14:34,128
NIH WIDE ACTIVITIES TO IMPROVE

371
00:14:34,128 --> 00:14:38,266
THE PUBLIC HEALTH OF OUR NATION.

372
00:14:38,266 --> 00:14:39,467
OUR SUCCESS REALLY DOES HINGE

373
00:14:39,467 --> 00:14:40,768
UPON THE SINNER GESTIC

374
00:14:40,768 --> 00:14:42,403
COORDINATION OF OUR OFFICES AND

375
00:14:42,403 --> 00:14:45,440
VITAL PARTNERSHIPS WITH OUR NIH

376
00:14:45,440 --> 00:14:48,610
INSTITUTES AND CENTERS, SO THIS

377
00:14:48,610 --> 00:14:51,212
IS THE ORGANIZATION DPC PSI, WE

378
00:14:51,212 --> 00:14:53,514
HAVE NUMEROUS OFFICES WITHIN THE

379
00:14:53,514 --> 00:14:57,285
DIVISION, AND EARLIER THIS YEAR,

380
00:14:57,285 --> 00:14:58,853
ACTUALLY, THE ENVIRONMENTAL

381
00:14:58,853 --> 00:15:01,189
INFLUENCES ON CHILD HEALTH

382
00:15:01,189 --> 00:15:02,257
OUTCOMES OR THE ECHO PROGRAM,

383
00:15:02,257 --> 00:15:04,559
THE ALL OF US RESEARCH PROGRAM,

384
00:15:04,559 --> 00:15:06,728
AND THE INCLUDE PROJECT WHICH IS

385
00:15:06,728 --> 00:15:08,129
THE INVESTIGATION OF CURRENT

386
00:15:08,129 --> 00:15:09,831
CONDITIONS ACROSS THE LIFE SPAN

387
00:15:09,831 --> 00:15:11,599
TO UNDERSTAND DOWNS SYNDROME ALL

388
00:15:11,599 --> 00:15:14,235
3 OF THOSE PROGRAMS WERE

389
00:15:14,235 --> 00:15:19,574
OFFICIALLY ADDED TO DPC PSI AS

390
00:15:19,574 --> 00:15:22,644
CROSS CUTTING NIH PROGRAMS THAT

391
00:15:22,644 --> 00:15:24,212
SERVE COMELEMENTARY AND ROBUST

392
00:15:24,212 --> 00:15:26,247
FASHIONS THAT ARE IN THE OFFICES

393
00:15:26,247 --> 00:15:28,783
THAT ARE IN DPC PSI, SO AMONG

394
00:15:28,783 --> 00:15:29,851
THE MANY OFFICES WE HAVE THE

395
00:15:29,851 --> 00:15:31,686
OFFICE OF RESEARCH ON WOMEN'S

396
00:15:31,686 --> 00:15:33,621
HEALTH, WHICH AS YOU ALL KNOW,

397
00:15:33,621 --> 00:15:36,024
REALLY SERVES AS THE FOLK AT

398
00:15:36,024 --> 00:15:36,858
POINT FOR WOMEN'S HEALTH

399
00:15:36,858 --> 00:15:40,728
RESEARCH AT THE NIH UNDER

400
00:15:40,728 --> 00:15:42,196
DR. CLAYTON'S LEADERSHIP.

401
00:15:42,196 --> 00:15:44,832
AND FOR OVER THIRD 30 YEARS,

402
00:15:44,832 --> 00:15:46,734
ORWHHAS LED A DIVERSE PORTFOLIO

403
00:15:46,734 --> 00:15:48,636
OF RESEARCH PROMULGATES, POLICY,

404
00:15:48,636 --> 00:15:50,104
PLANNING INITTIAIVE ITS,

405
00:15:50,104 --> 00:15:51,306
COORDINATION EFFORTS AND

406
00:15:51,306 --> 00:15:52,640
RESOURCE DEVELOPMENT PROJECTS

407
00:15:52,640 --> 00:15:55,343
THAT REALLY AIM TO ENHANCE AND

408
00:15:55,343 --> 00:15:56,411
EXPAND WOMEN'S HEALTH RESEARCH

409
00:15:56,411 --> 00:15:58,246
THAT PROMOTE THE INCLUSION OF

410
00:15:58,246 --> 00:16:02,116
WOMEN IN CLINICAL RESEARCH, THAT

411
00:16:02,116 --> 00:16:03,151
PROMOTE CAREER ADVANCEMENT FOR

412
00:16:03,151 --> 00:16:05,620
WOMEN IN HEALTH RESEARCH

413
00:16:05,620 --> 00:16:07,055
CAREERS, AND ADVANCE THE

414
00:16:07,055 --> 00:16:11,759
APPLICATION OF THE NIH SEX AS A

415
00:16:11,759 --> 00:16:13,194
BIOLOGICAL VARIABLE POLICY.

416
00:16:13,194 --> 00:16:18,533
SO ORWH YOU KNOW IS ABSOLUTELY

417
00:16:18,533 --> 00:16:20,501
INSTRUMENTAL IN ADDRESSING MANY

418
00:16:20,501 --> 00:16:23,171
KEY NIH PRIORITIES AND HHS

419
00:16:23,171 --> 00:16:23,805
PRIORITIES THROUGH COLLABORATION

420
00:16:23,805 --> 00:16:28,609
WITH ALL THE DIFFERENT

421
00:16:28,609 --> 00:16:28,876
 INSTITUTE

422
00:16:28,876 --> 00:16:29,210
ANDS CENTERS.

423
00:16:29,210 --> 00:16:33,047
SO FIRST I WANT TO GO OVER

424
00:16:33,047 --> 00:16:34,916
BRIEFLY IN TERMS OF NIH

425
00:16:34,916 --> 00:16:36,784
PRIORITIES AND KIND OF HOW THOSE

426
00:16:36,784 --> 00:16:39,687
RELATE TO WOMEN'S HEALTH

427
00:16:39,687 --> 00:16:39,954
RESEARCH.

428
00:16:39,954 --> 00:16:41,956
I WILL START WITH THE NIH

429
00:16:41,956 --> 00:16:43,224
DIRECTOR'S PRIORITIES AND THEN I

430
00:16:43,224 --> 00:16:45,560
WILL GO GRANULAR AND TALK ABOUT

431
00:16:45,560 --> 00:16:50,298
MY PRIORITIES AS ACTING DPC PSI

432
00:16:50,298 --> 00:16:50,898
DIRECTOR.

433
00:16:50,898 --> 00:16:55,269
AND DR. BHATTACHARYA HAS

434
00:16:55,269 --> 00:16:57,672
PRESENTED ON THESE AT A HIGH

435
00:16:57,672 --> 00:16:58,039
LEVEL.

436
00:16:58,039 --> 00:17:00,575
FIRST THERE'S STRONG FOCUS ON

437
00:17:00,575 --> 00:17:01,809
IMPROVING POPULATION HEALTH AND

438
00:17:01,809 --> 00:17:03,644
THIS INCLUDES EVERY PERSON THAT

439
00:17:03,644 --> 00:17:06,748
LIVES IN THIS COUNTRY, YOU KNOW

440
00:17:06,748 --> 00:17:10,551
REGARDLESS OF SEX, GENDER,

441
00:17:10,551 --> 00:17:11,219
SOCIOECONOMIC STATUS, ETHNICITY,

442
00:17:11,219 --> 00:17:14,389
ET CETERA AND TO ENABLE US TO

443
00:17:14,389 --> 00:17:15,590
TACKLE THE CHRONIC DISEASE

444
00:17:15,590 --> 00:17:17,091
CRISIS THAT HAS REALLY IMPACTED

445
00:17:17,091 --> 00:17:19,093
THE WELL BEING OF MANY

446
00:17:19,093 --> 00:17:19,527
AMERICANS. 

447
00:17:19,527 --> 00:17:20,128
OH DEAR.

448
00:17:20,128 --> 00:17:24,932
THAT WAS NOT RIGHT.

449
00:17:24,932 --> 00:17:26,134
OUR TECH FOLKS TO HELP ME GET

450
00:17:26,134 --> 00:17:29,537
BACK TO WHERE I WAS.

451
00:17:29,537 --> 00:17:32,206
OKAY, THE NEXT PRIORITY, ON

452
00:17:32,206 --> 00:17:33,041
REPRODUCIBILITY AND RIGOR, SO

453
00:17:33,041 --> 00:17:37,245
THANK YOU FOR THAT -- INSURING

454
00:17:37,245 --> 00:17:40,515
THAT THE NIH IS SUPPORTING

455
00:17:40,515 --> 00:17:42,116
SCIENCE THAT IS HIGHLY

456
00:17:42,116 --> 00:17:46,721
DEFENSIBLE, THAT IS RIGOROUS,

457
00:17:46,721 --> 00:17:47,388
REPRODUCIBLE, IT'S UNBIOSED AND

458
00:17:47,388 --> 00:17:49,524
WE HAVE A NUMBER OF INITIATIVES

459
00:17:49,524 --> 00:17:50,958
THAT WE'VE BEEN EXPANDING TO TRY

460
00:17:50,958 --> 00:17:53,694
AND INCREASE THE SUPPORT FOR

461
00:17:53,694 --> 00:17:56,531
REPLICATION SCIENCE AND

462
00:17:56,531 --> 00:17:56,931
REPRODUCIBILITY.

463
00:17:56,931 --> 00:17:58,066
I THINK THAT NO 1 WOULD ARGUE

464
00:17:58,066 --> 00:18:01,202
WITH THE FACT THAT NIH AS THE

465
00:18:01,202 --> 00:18:02,036
LARGEST FUNDER OF BIOMEDICAL

466
00:18:02,036 --> 00:18:03,204
RESEARCH IN THE WORLD HAS A

467
00:18:03,204 --> 00:18:05,073
RESPONSIBILITY TO BE AT THE

468
00:18:05,073 --> 00:18:07,208
FOREFRONT OF BIOMEDICAL

469
00:18:07,208 --> 00:18:09,110
INNOVATION AND USING THE MOST

470
00:18:09,110 --> 00:18:11,312
CUTTING EDGE SCIENCE TO ADDRESS

471
00:18:11,312 --> 00:18:13,381
BOTH EXISTING AND EMERGING

472
00:18:13,381 --> 00:18:13,881
PROBLEMS.

473
00:18:13,881 --> 00:18:15,316
WE HAVE TO INSURE THAT THE

474
00:18:15,316 --> 00:18:18,152
RESEARCH THAT WE SUPPORT IS BOTH

475
00:18:18,152 --> 00:18:21,689
SAFE AND TRANSPARENT AND MEETS

476
00:18:21,689 --> 00:18:22,824
HIGHEST ETHICAL STANDARDS AND

477
00:18:22,824 --> 00:18:26,494
THAT WE ARE SUPPORTING ACADEMIC

478
00:18:26,494 --> 00:18:29,864
FREEDOM AND ENCOURAGING

479
00:18:29,864 --> 00:18:32,800
DISSENTING OPINIONS AND REALLY

480
00:18:32,800 --> 00:18:36,104
CREATING AND FOSTERING AN

481
00:18:36,104 --> 00:18:37,071
ENVIRONMENT WHERE VARIED

482
00:18:37,071 --> 00:18:38,639
PERSPECTIVES ARE VALUED AND

483
00:18:38,639 --> 00:18:39,373
SUPPORTED AND ENCOURAGED.

484
00:18:39,373 --> 00:18:41,742
I THINK ACROSS ALL OF THESE

485
00:18:41,742 --> 00:18:43,578
PRIORITIES INCORPORATING SEX AS

486
00:18:43,578 --> 00:18:45,346
A BIOLOGICAL VARIABLE AND

487
00:18:45,346 --> 00:18:46,380
ABSOLUTELY ESSENTIAL, SO IT, YOU

488
00:18:46,380 --> 00:18:50,384
KNOW TO GO THROUGH EACH OF THEM,

489
00:18:50,384 --> 00:18:51,319
IT STRENGTHENS POPULATION HEALTH

490
00:18:51,319 --> 00:18:52,587
OF COURSE BY INSURING THAT THE

491
00:18:52,587 --> 00:18:54,689
RESEARCH NOT ONLY REFLECTS BUT

492
00:18:54,689 --> 00:18:56,757
ACCOUNTS FOR THE BIOLOGICAL

493
00:18:56,757 --> 00:18:57,692
DIFFERENCES THAT INFLUENCE

494
00:18:57,692 --> 00:19:00,394
DISEASE RISK AND PROGRESSION AND

495
00:19:00,394 --> 00:19:00,862
TREATMENT.

496
00:19:00,862 --> 00:19:03,364
IT IMPROVING SCIENTIFIC RIGOR

497
00:19:03,364 --> 00:19:05,299
AND REPRODUCIBILITY BY

498
00:19:05,299 --> 00:19:06,367
UNCOVERING CRITICAL SEX BASED

499
00:19:06,367 --> 00:19:09,570
PATTERNS THAT WOULD OTHERWISE BE

500
00:19:09,570 --> 00:19:11,038
MISSED, IF SECOND BIOLOGICAL

501
00:19:11,038 --> 00:19:14,742
VARIABLE WAS NOT CONSIDERED OR

502
00:19:14,742 --> 00:19:18,079
IF THE DATA WERE NOT

503
00:19:18,079 --> 00:19:18,613
DEDEGRADATIONGREGATED, IT

504
00:19:18,613 --> 00:19:19,680
ENHANCES RESEARCH SAFETY THROUGH

505
00:19:19,680 --> 00:19:21,182
UNDERSTANDING OF HOW

506
00:19:21,182 --> 00:19:22,917
INTERVENTIONS AFFECT DIFFERENT

507
00:19:22,917 --> 00:19:24,385
POPULATIONS, IF WE DON'T PAY

508
00:19:24,385 --> 00:19:26,587
ATTENTION TO SEX DIFFERENCES, WE

509
00:19:26,587 --> 00:19:28,523
REALLY RISK EXPOSING INDIVIDUALS

510
00:19:28,523 --> 00:19:30,491
TO UNNECESSARY HARM OR FAILING

511
00:19:30,491 --> 00:19:33,394
TO DETECT RISKS THAT ARE SEX

512
00:19:33,394 --> 00:19:34,195
SPECIFIC.

513
00:19:34,195 --> 00:19:39,467
AND IT BUILDS TRANS TRANSPARENCY

514
00:19:39,467 --> 00:19:40,568
REQUIRING CLEAR REPORTING.

515
00:19:40,568 --> 00:19:43,070
SO FOR EXAMPLE, THE 21st

516
00:19:43,070 --> 00:19:45,373
CENTURY CURES ACT REQUIRES

517
00:19:45,373 --> 00:19:47,575
APPLICABLE NIH PHASE 3 TRIALS TO

518
00:19:47,575 --> 00:19:48,743
REPORT RESULTS AND VALID

519
00:19:48,743 --> 00:19:51,846
ANALYSIS BY SEX, RACE, ETHNICITY

520
00:19:51,846 --> 00:19:53,681
IN CLINICALTRIALS.GOV, SO WITH

521
00:19:53,681 --> 00:19:55,082
THAT WE'RE BUILDING TRUST BUT

522
00:19:55,082 --> 00:19:56,017
WE'RE ALSO EMPOWERING OTHER

523
00:19:56,017 --> 00:19:58,653
SCIENTISTS TO BUILD UPON OUR

524
00:19:58,653 --> 00:19:58,853
WORK.

525
00:19:58,853 --> 00:20:02,056
OKAY, NOW THAT I HAVE SHARED THE

526
00:20:02,056 --> 00:20:03,624
NIH DIRECTOR'S PRIORITIES, I

527
00:20:03,624 --> 00:20:04,792
WANT TO SHARE MY PRIORITIES

528
00:20:04,792 --> 00:20:07,361
WHICH ARE VERY CONSISTENT WITH

529
00:20:07,361 --> 00:20:08,996
THE NIH DIRECTORS, BUT ARE A

530
00:20:08,996 --> 00:20:13,634
LITTLE MORE GRANULAR, SO, FIRST,

531
00:20:13,634 --> 00:20:15,036
IDENTIFYING AREAS OF STRATEGIC

532
00:20:15,036 --> 00:20:17,004
INVESTMENT THAT CAN BE USED TO

533
00:20:17,004 --> 00:20:19,140
TRANSFORM THE SCIENCE THAT WE'RE

534
00:20:19,140 --> 00:20:21,642
DOING AND HAVE STRONG POTENTIAL

535
00:20:21,642 --> 00:20:24,779
FOR IMPROVING OUR PUBLIC HEALTH

536
00:20:24,779 --> 00:20:30,418
PROTECTION AND OUR DISDISCOVERY

537
00:20:30,418 --> 00:20:32,220
OF IMPROVED INTERVENTIONS, SO 1

538
00:20:32,220 --> 00:20:33,287
EXAMPLE OF THIS AREA AS YOU

539
00:20:33,287 --> 00:20:34,889
MIGHT HAVE GUESSED FROM MY

540
00:20:34,889 --> 00:20:36,090
BACKGROUND WHEN DR. CLAYTON WAS

541
00:20:36,090 --> 00:20:38,292
INTRODUCING ME IS AN AREA CALLED

542
00:20:38,292 --> 00:20:41,395
NEW APPROACH METHODOLOGIES SO

543
00:20:41,395 --> 00:20:42,797
USING THE MOST ADVANCED

544
00:20:42,797 --> 00:20:44,165
TECHNOLOGY WE HAVE AVAILABLE TO

545
00:20:44,165 --> 00:20:47,802
US TO DEVELOP AND VALIDATE AND

546
00:20:47,802 --> 00:20:50,338
APPLY HUMAN BIOLOGY BASED

547
00:20:50,338 --> 00:20:51,339
INTEGRATED STRATEGIES TO

548
00:20:51,339 --> 00:20:53,040
UNDERSTAND HUMAN HEALTH AND

549
00:20:53,040 --> 00:20:54,475
DISEASE PATHWAYS AND I WILL TALK

550
00:20:54,475 --> 00:20:58,179
ABOUT THAT IN A LITTLE MORE

551
00:20:58,179 --> 00:20:59,480
DETAIL LATER.

552
00:20:59,480 --> 00:21:00,514
STRONGER PARTNERSHIPS SO I CAME

553
00:21:00,514 --> 00:21:06,153
FROM YOU KNOW DIRECTING A

554
00:21:06,153 --> 00:21:06,754
COMMITTEE THAT INCLUDED 18

555
00:21:06,754 --> 00:21:08,723
FEDERAL AGENCIES SO I HAVE A LOT

556
00:21:08,723 --> 00:21:10,925
OF EXPERIENCE IN CULTIVATING AND

557
00:21:10,925 --> 00:21:12,760
STRENGTHENING PARTNERSHIPS AND

558
00:21:12,760 --> 00:21:14,362
COLLABORATIONS ACROSS THE

559
00:21:14,362 --> 00:21:16,163
FEDERAL GOVERNMENT AND ACROSS A

560
00:21:16,163 --> 00:21:18,099
BROAD RANGE OF STAKEHOLDERS BOTH

561
00:21:18,099 --> 00:21:20,901
IN THE SCIENTIFIC COMMUNITY AND

562
00:21:20,901 --> 00:21:24,839
IN THE GENERAL PUBLIC, AND IN

563
00:21:24,839 --> 00:21:26,440
ADVOCACY ORGANIZATIONS AND NG

564
00:21:26,440 --> 00:21:27,608
Os AND THERE'S JUST SO MUCH

565
00:21:27,608 --> 00:21:31,245
THAT CAN BE GAINED FROM

566
00:21:31,245 --> 00:21:33,180
PARTNERSHIPS BOTH WITHIN THE 

567
00:21:33,180 --> 00:21:35,750
GOVERNMENT AND ACROSS ACADEMIA

568
00:21:35,750 --> 00:21:36,651
AND PUBLIC-PRIVATE PARTNERSHIPS

569
00:21:36,651 --> 00:21:38,686
TO BE MORE RESPONSIVE TO

570
00:21:38,686 --> 00:21:39,987
NATIONAL HEALTH PRIORITIES AND

571
00:21:39,987 --> 00:21:41,956
TO LEVERAGE OUR SHARED

572
00:21:41,956 --> 00:21:46,193
SCIENTIFIC EXPERTISE AND

573
00:21:46,193 --> 00:21:46,460
RESOURCES.

574
00:21:46,460 --> 00:21:48,296
I AM ALSO A DATA SCIENTIST AT

575
00:21:48,296 --> 00:21:52,266
HEART, THAT'S MY BACKGROUND IS

576
00:21:52,266 --> 00:21:54,468
IN COMPUTATIONAL SYSTEMS BIOLOGY

577
00:21:54,468 --> 00:21:55,736
AND APPLIED MATHEMATICAL

578
00:21:55,736 --> 00:21:59,206
MODELING AND SO DATA IS MY

579
00:21:59,206 --> 00:22:00,975
LANGUAGE, DATA IS MY BREAD AND

580
00:22:00,975 --> 00:22:02,543
BUTTER SO INCORPORATING REALTIME

581
00:22:02,543 --> 00:22:03,944
DATA AND PERFORMANCE METRICS

582
00:22:03,944 --> 00:22:06,314
INTO OUR PROCESSES TO REALLY

583
00:22:06,314 --> 00:22:07,948
INFORM OUR PROGRAMMING AND

584
00:22:07,948 --> 00:22:09,984
PLANNING AND RESOURCE

585
00:22:09,984 --> 00:22:10,351
ALLOCATION.

586
00:22:10,351 --> 00:22:11,018
WORKFORCE DEVELOPMENT IS

587
00:22:11,018 --> 00:22:12,753
INCREDIBLE LOAMACYY IMPORTANT TO

588
00:22:12,753 --> 00:22:14,121
ME, PROVIDING AN ENVIRONMENT

589
00:22:14,121 --> 00:22:16,090
WHERE EVERYONE CAN THRIVE AND

590
00:22:16,090 --> 00:22:18,826
REALIZE THEIR CAREER GOALS AND

591
00:22:18,826 --> 00:22:20,294
OPPORTUNITIES AND IN

592
00:22:20,294 --> 00:22:22,630
ACCELERATING TRANSLATION THROUGH

593
00:22:22,630 --> 00:22:23,197
PRACTICAL SOLUTIONS.

594
00:22:23,197 --> 00:22:24,131
SO THINKING ABOUT NOT JUST WHAT

595
00:22:24,131 --> 00:22:25,700
WE WANT TO DO BUT HOW WE WANT TO

596
00:22:25,700 --> 00:22:28,936
DO IT AND ENGAGING TECHNIQUES

597
00:22:28,936 --> 00:22:33,741
LIKE IMPLEMENTATION SCIENCE TO

598
00:22:33,741 --> 00:22:34,742
DO THAT PLANNING.

599
00:22:34,742 --> 00:22:36,143
OKAY, I PROBABLY DON'T HAVE TO

600
00:22:36,143 --> 00:22:36,977
LECTURE THIS AUDIENCE ABOUT THE

601
00:22:36,977 --> 00:22:38,346
FACT THAT THERE ARE DIFFERENCES

602
00:22:38,346 --> 00:22:41,549
IN HEALTH FOR WOMEN, WE KNOW

603
00:22:41,549 --> 00:22:44,185
THAT ACROSS THE WORLD WOMEN HAVE

604
00:22:44,185 --> 00:22:45,052
LONGER LIFE EXPECTANCYS THAN MEN

605
00:22:45,052 --> 00:22:48,656
IN THE U.S. FOR MORE THAN A

606
00:22:48,656 --> 00:22:49,724
CENTURY WOMEN HAVE ACTUALLY

607
00:22:49,724 --> 00:22:51,659
OUTLIVED MEN WHICH IS

608
00:22:51,659 --> 00:22:52,793
ATTRIBUTABLE TO LOWER

609
00:22:52,793 --> 00:22:54,562
CARDIOVASCULAR AND LUNG CANCER

610
00:22:54,562 --> 00:22:55,963
DEATH RATES, RELATED LARGELY TO

611
00:22:55,963 --> 00:22:57,331
DIFFERENCES IN SMOKING BEHAVIOR

612
00:22:57,331 --> 00:22:58,499
WORLD WIDE, BUT WE ALSO KNOW

613
00:22:58,499 --> 00:23:00,468
THAT WOMEN ARE MORE LIKELY TO

614
00:23:00,468 --> 00:23:03,371
LIVE WITH CHRONIC DISEASE, SO

615
00:23:03,371 --> 00:23:06,173
20% OF U.S. WOMEN AGE 18-64 HAVE

616
00:23:06,173 --> 00:23:10,077
2 OR MORE CHRONIC CONDITIONS,

617
00:23:10,077 --> 00:23:11,712
MULTIMORBIDITY, IN WOMEN THIS

618
00:23:11,712 --> 00:23:13,514
OFTEN INCLUDES BOTH PHYSICAL AND

619
00:23:13,514 --> 00:23:15,082
MENTAL HEALTH CONDITIONS WHICH

620
00:23:15,082 --> 00:23:15,883
OBVIOUSLY REALLY FURTHER IMPACT

621
00:23:15,883 --> 00:23:19,019
THE QUALITY OF LIFE AND THE

622
00:23:19,019 --> 00:23:20,588
HEALTHCARE NEEDS AND BIOLOGICAL

623
00:23:20,588 --> 00:23:22,256
DIFFERENCES IN ADDITION TO

624
00:23:22,256 --> 00:23:23,290
ENVIRONMENTAL FACTORS REALLY

625
00:23:23,290 --> 00:23:24,825
INFLUENCE THE ONSET PROGRESSION

626
00:23:24,825 --> 00:23:26,127
AND TREATMENT OF DISEASES, SO

627
00:23:26,127 --> 00:23:27,428
THAT'S 1 OF THE REASONS IT'S

628
00:23:27,428 --> 00:23:29,797
CRUCIAL TO INSURE THAT WOMEN ARE

629
00:23:29,797 --> 00:23:31,632
INCLUDED IN RESEARCH AND THAT

630
00:23:31,632 --> 00:23:34,735
SEX DIFFERENCES ARE ADEQUATELY

631
00:23:34,735 --> 00:23:35,102
CONSIDERED.

632
00:23:35,102 --> 00:23:36,170
ADDRESSING AMERICA'S EPIDEMIC OF

633
00:23:36,170 --> 00:23:37,638
CHRONIC ILLNESS IS A TOP

634
00:23:37,638 --> 00:23:39,807
PRIORITY OF HHS AND THE

635
00:23:39,807 --> 00:23:41,976
ADMINISTRATION AND AS A MAJOR

636
00:23:41,976 --> 00:23:43,577
PILLAR OF THE MAKE AMERICA

637
00:23:43,577 --> 00:23:44,745
HEALTHY AGAIN COMMISSION AND I

638
00:23:44,745 --> 00:23:47,815
THINK THAT NIH AND DPC PSI AND

639
00:23:47,815 --> 00:23:49,517
ORWH ARE REALLY POISED TO BE

640
00:23:49,517 --> 00:23:52,720
LEADERS IN THIS SPACE.

641
00:23:52,720 --> 00:23:53,888
CHRONIC DISEASE AND

642
00:23:53,888 --> 00:23:54,955
MULTIMORBIDITY ARE MAJOR

643
00:23:54,955 --> 00:23:57,024
COMPONENTS OF THE NIH WIDE

644
00:23:57,024 --> 00:23:58,726
STRATEGIC PLAN ON THE RESEARCH

645
00:23:58,726 --> 00:24:01,429
OF HEALTH FOR WOMEN ON FY24-28,

646
00:24:01,429 --> 00:24:04,899
THIS WAS PUBLISHED LAST YEAR ON

647
00:24:04,899 --> 00:24:06,867
MAY 15 OF 2024 AND THERE ARE

648
00:24:06,867 --> 00:24:09,503
OTHER CROSS CUTTING THEMES IN

649
00:24:09,503 --> 00:24:10,771
THERE LIKE INTERDISCIPLINARY

650
00:24:10,771 --> 00:24:11,639
CROSS COLLABORATION, PRECISION

651
00:24:11,639 --> 00:24:13,140
MEDICINE, INCLUSION OF GIRLS IN

652
00:24:13,140 --> 00:24:14,308
CLINICAL STUDIES, SEX

653
00:24:14,308 --> 00:24:15,009
DIFFERENCES RESEARCH, AND

654
00:24:15,009 --> 00:24:17,978
PREVENTIVE CARE AND SERVICES.

655
00:24:17,978 --> 00:24:19,480
AUTOIMMUNE DISEASES, IS A CLASS

656
00:24:19,480 --> 00:24:21,449
OF CHRONIC DISEASES THAT

657
00:24:21,449 --> 00:24:23,050
DISPROPORTIONATELY AFFECT WOMEN,

658
00:24:23,050 --> 00:24:25,653
AND ABOUT 8 PERCENT OF THE U.S.

659
00:24:25,653 --> 00:24:27,488
POPULATION IS CURRENTLY LIVING

660
00:24:27,488 --> 00:24:28,789
WITH AN AUTOIMMUNE DISEASE AND

661
00:24:28,789 --> 00:24:31,158
NEARLY 80% OF THOSE ARE WOMEN.

662
00:24:31,158 --> 00:24:34,261
AND SO TO ACCELERATE PROGRESS IN

663
00:24:34,261 --> 00:24:36,330
THIS AREA, IN 2022, CONGRESS

664
00:24:36,330 --> 00:24:38,065
DIRECTED NIH TO ESTABLISH AN

665
00:24:38,065 --> 00:24:40,468
OFFICE OF AUTOIMMUNE DISEASE

666
00:24:40,468 --> 00:24:41,669
RESEARCH WITHIN ORWH AND THEY'VE

667
00:24:41,669 --> 00:24:44,972
BEEN WORKING REALLY HARD ON

668
00:24:44,972 --> 00:24:45,673
THEIR INAUGURAL STRATEGIC PLAN

669
00:24:45,673 --> 00:24:48,609
WHICH WILL BE RELEASED SOON.

670
00:24:48,609 --> 00:24:51,712
NOW NIH HAS SUPPORTED NUMEROUS

671
00:24:51,712 --> 00:24:54,248
EFFORTS TO ADDRESS CHRONIC DECS

672
00:24:54,248 --> 00:24:55,416
IN WOMEN, THERE'S JUST A FEW

673
00:24:55,416 --> 00:24:56,951
EXAMPLES ON THE SLIDE HERE, WE

674
00:24:56,951 --> 00:24:58,719
KNOW THAT MORE THAN 250,000

675
00:24:58,719 --> 00:25:00,154
WOMEN IN THE U.S. ARE ESTIMATED

676
00:25:00,154 --> 00:25:05,526
TO BE LIVING WITH HIV, OF WHOM

677
00:25:05,526 --> 00:25:08,496
5000 HAVE ACQUIRED INFECTION AND

678
00:25:08,496 --> 00:25:13,567
DESPITE KNOWN SEX INFLUULENCES

679
00:25:13,567 --> 00:25:17,204
ON DISEASE AND IMMUNE PATHOGENS,

680
00:25:17,204 --> 00:25:18,973
ONLY ABOUT 17% ARE RECRUITED

681
00:25:18,973 --> 00:25:21,008
INTO HAD HIV CLINICAL TRIALS

682
00:25:21,008 --> 00:25:22,510
WHICH HIGHLIGHTS THE URGENT NEED

683
00:25:22,510 --> 00:25:24,111
FOR RESEARCH AND ADDRESSING THE

684
00:25:24,111 --> 00:25:26,013
IMPACT OF HIV IN WOMEN ACROSS

685
00:25:26,013 --> 00:25:27,982
THE LIFE SPAN.

686
00:25:27,982 --> 00:25:30,384
ORWH AND DPC PSI OFFICE OF AIDS

687
00:25:30,384 --> 00:25:32,353
RESEARCH LAWRCHED THE HIV IN

688
00:25:32,353 --> 00:25:33,621
WOMEN SIGNATURE PROGRAM, THE

689
00:25:33,621 --> 00:25:35,022
CORNERSTONE OF THIS PROGRAM IS

690
00:25:35,022 --> 00:25:36,857
THAT IRPT SECTIONAL AND DATA

691
00:25:36,857 --> 00:25:38,392
DRIVEN APPROACH TO RESEARCH ON

692
00:25:38,392 --> 00:25:40,394
HIV AND WOMEN.

693
00:25:40,394 --> 00:25:41,929
AND THE SIGNATURE PROMULGATE

694
00:25:41,929 --> 00:25:43,297
REALLY ADVANCES THE NIH VISION

695
00:25:43,297 --> 00:25:44,965
FOR WOMEN'S HEALTH WHICH REALLY

696
00:25:44,965 --> 00:25:48,235
ENVISIONS A WORLD IN WHICH ALL

697
00:25:48,235 --> 00:25:49,870
WOMEN AND GIRLS RECEIVE EVIDENCE

698
00:25:49,870 --> 00:25:51,906
BASED CARE, PREVENTION AND

699
00:25:51,906 --> 00:25:53,641
TREATMENT TAYLORED TO THEIR

700
00:25:53,641 --> 00:25:55,276
UNIQUE NEEDS, CIRCUMSTANCES AND

701
00:25:55,276 --> 00:25:57,244
GOALS AND A SECOND EXAMPLE IS

702
00:25:57,244 --> 00:25:58,546
CARDIOVASCULAR DISEASE, AND IT

703
00:25:58,546 --> 00:25:59,914
REMAINS THE LEADING CAUSE OF

704
00:25:59,914 --> 00:26:02,316
DEATH FOR WOMEN IN THE U.S. WITH

705
00:26:02,316 --> 00:26:03,918
MORE THAN 60 MILLION LIVING WITH

706
00:26:03,918 --> 00:26:05,619
HEART DISEASE AND WOMEN OFTEN

707
00:26:05,619 --> 00:26:09,690
REPORT VERY DIFFERENT SYMPTOMS

708
00:26:09,690 --> 00:26:11,992
THAN MEN, SO PRESSURE,

709
00:26:11,992 --> 00:26:14,094
DIZZINESS, NAUSEA, THAT CAN LEAD

710
00:26:14,094 --> 00:26:17,531
TO DIAGNOSIS AND UNDERTREATMENT.

711
00:26:17,531 --> 00:26:18,899
IN 2002, NHLBI, THE NATIONAL

712
00:26:18,899 --> 00:26:28,208
HEART LUNG AND BLOOD INSTITUTE

713
00:26:28,208 --> 00:26:29,877
CREATED HEART TRUTH, IT WAS

714
00:26:29,877 --> 00:26:33,147
DESIGNED TO RAISE AWARENESS AS

715
00:26:33,147 --> 00:26:36,050
HEART DISEASE AS A MORBIDITY

716
00:26:36,050 --> 00:26:42,022
ISSUE IN WOMEN.

717
00:26:42,022 --> 00:26:43,290
MENOPAUSE WITH SYMPTOMS ALONG

718
00:26:43,290 --> 00:26:44,325
WITH INCREASED RISK THAT STAGE

719
00:26:44,325 --> 00:26:47,995
IN LIFE OF DEVELOPING 1 OR MORE

720
00:26:47,995 --> 00:26:50,364
CHRONIC DISEASES, POSES REALLY

721
00:26:50,364 --> 00:26:51,198
SPECIFIC CHALLENGES IN

722
00:26:51,198 --> 00:26:54,201
HEALTHCARE FOR WOMEN BUT ALSO

723
00:26:54,201 --> 00:26:54,868
REPRESENTS AN OPPORTUNITY.

724
00:26:54,868 --> 00:26:57,571
SO BUILDING ON INSIGHTS FROM NIH

725
00:26:57,571 --> 00:27:00,074
RESEARCH, THE FIRST EVER

726
00:27:00,074 --> 00:27:01,642
MULTISECTOR MENOPAUSE PATHWAY TO

727
00:27:01,642 --> 00:27:03,777
PREVENTION PROGRAM IS SET TO

728
00:27:03,777 --> 00:27:05,412
LAUNCH THIS YEAR AND IS

729
00:27:05,412 --> 00:27:08,082
COLLECTING EVIDENCE RELEVANT TO

730
00:27:08,082 --> 00:27:11,485
MANAGING MOAN O PAUSE SYMPTOMS

731
00:27:11,485 --> 00:27:14,855
AND MANAGING HEALTH IN THE EARLY

732
00:27:14,855 --> 00:27:16,323
POST MENOPAUSAL PHASE.

733
00:27:16,323 --> 00:27:17,257
SOMETHING ELSE THAT'S NEAR AND

734
00:27:17,257 --> 00:27:19,393
DEAR TO MY HEART IS HOW WE ARE

735
00:27:19,393 --> 00:27:24,932
GOING TO BE RESPONSIBLY AND

736
00:27:24,932 --> 00:27:26,634
ETHICALLY AMRIING AI TO OUR

737
00:27:26,634 --> 00:27:27,935
RESEARCH CAPABILITIES IN

738
00:27:27,935 --> 00:27:30,371
ALIGNMENT WITH THESE NIH

739
00:27:30,371 --> 00:27:30,938
PRIORITIES.

740
00:27:30,938 --> 00:27:33,040
SO, AI IS UNAVOIDABLE, IT'S

741
00:27:33,040 --> 00:27:34,341
EVERYWHERE IN OUR LIVES NOW AND

742
00:27:34,341 --> 00:27:38,145
SO WE REALLY HAVE A

743
00:27:38,145 --> 00:27:41,548
RESPONSIBILITY TO APPLY IT IN

744
00:27:41,548 --> 00:27:43,050
THE MOST INTELLIGENT AND ETHICAL

745
00:27:43,050 --> 00:27:45,219
WAYS TO HELP ADVANCE RESEARCH IN

746
00:27:45,219 --> 00:27:46,987
WOMEN'S HEALTH AND MANY OTHER

747
00:27:46,987 --> 00:27:47,187
AREAS.

748
00:27:47,187 --> 00:27:48,956
SO THERE'S A NUMBER OF DRIVERS

749
00:27:48,956 --> 00:27:52,226
BEHIND THE GROWTH AND AI HEALTH

750
00:27:52,226 --> 00:27:52,559
APPLICATIONS.

751
00:27:52,559 --> 00:27:54,628
THIS INCLUDES LARGE DATA SETS

752
00:27:54,628 --> 00:27:57,064
THAT ARE BECOMING MORE

753
00:27:57,064 --> 00:27:58,632
ACCESSIBLE AND COMPUTATIONALLY

754
00:27:58,632 --> 00:28:01,168
FRIENDLY THAN EVER BEFORE.

755
00:28:01,168 --> 00:28:03,270
VERY DIVERSE MULTIMODAL DATA

756
00:28:03,270 --> 00:28:04,805
SETS, IMPROVEMENTS IN HOW THOSE

757
00:28:04,805 --> 00:28:09,209
DATA ARE CAPTURED AND REPORTED,

758
00:28:09,209 --> 00:28:11,111
DATA STANDARDS, IMPROVED

759
00:28:11,111 --> 00:28:12,546
INTEROPERABILITY BETWEEN THOSE

760
00:28:12,546 --> 00:28:14,214
DAT AINCREASED COMPUTING POWER,

761
00:28:14,214 --> 00:28:16,617
ADVANCEMENTS IN DATA PRIVACY,  

762
00:28:16,617 --> 00:28:17,685
PERSEVERING APPROACHES, THIS IS

763
00:28:17,685 --> 00:28:22,623
SOMETHING THAT NIH IS INCREDIBLY

764
00:28:22,623 --> 00:28:24,124
INVESTED IN FOR PATIENT SECURITY

765
00:28:24,124 --> 00:28:24,825
AND PROTECTION.

766
00:28:24,825 --> 00:28:26,026
AND THEN BREAK THROUGH IN

767
00:28:26,026 --> 00:28:29,463
METHODS ON ANALYZE THAT DATA, SO

768
00:28:29,463 --> 00:28:32,166
DEEP NEURAL NETS, REINFORCEMENT

769
00:28:32,166 --> 00:28:35,102
LEARNINGS, ET CETERA, THIS IS

770
00:28:35,102 --> 00:28:36,437
JUST A FIGURE FROM AN ARTICLE

771
00:28:36,437 --> 00:28:38,839
THAT I WROTE WITH A PREGNANT

772
00:28:38,839 --> 00:28:41,875
COLLEAGUE ON HOW AI IS BEING

773
00:28:41,875 --> 00:28:42,609
APPLIED ACROSS SCIENTIFIC

774
00:28:42,609 --> 00:28:44,211
DISCIPLINES WITH A FOCUS ON

775
00:28:44,211 --> 00:28:46,814
TOXICOLOGY AND PUBLIC HEALTH

776
00:28:46,814 --> 00:28:47,247
PROTECTION.

777
00:28:47,247 --> 00:28:52,052
AS PART OF THIS INTEREST IN AI,

778
00:28:52,052 --> 00:28:54,888
THE NIH DIRECTOR INTENDS TO

779
00:28:54,888 --> 00:28:56,590
DEVELOP A OVERALL DATA PLATFORM

780
00:28:56,590 --> 00:28:57,257
TO ACCELERATE DISCOVERY.

781
00:28:57,257 --> 00:28:58,292
THIS IS NOT SOMETHING WE'RE

782
00:28:58,292 --> 00:29:00,561
DOING FROM SCRATCH, WE'RE

783
00:29:00,561 --> 00:29:02,896
BUILDING  ON EXISTING THE CURE,

784
00:29:02,896 --> 00:29:07,868
NIH RESOURCES, LIKE THE NATIONAL

785
00:29:07,868 --> 00:29:11,004
CLINICAL COHORT COLLABORATIVE AT

786
00:29:11,004 --> 00:29:15,175
NCATS TO ACTUALLY UNITE DATA

787
00:29:15,175 --> 00:29:19,346
SOURCES FROM SOURCES LIKE HEALTH

788
00:29:19,346 --> 00:29:21,315
ORGANIZATIONS OR CLAIMS OR

789
00:29:21,315 --> 00:29:22,583
ENVIRONMENTAL DATA,

790
00:29:22,583 --> 00:29:23,984
ENVIRONMENTAL EXPOSURE DATA,

791
00:29:23,984 --> 00:29:25,052
SENSORS, WEARABLES AND WE WOULD

792
00:29:25,052 --> 00:29:29,656
LOAMACYIC  -- LIKE TO ATTAIN

793
00:29:29,656 --> 00:29:32,659
BROAD COVERAGE OF THE U.S.

794
00:29:32,659 --> 00:29:33,961
POPULATION BY UTILIZING FEDERAL

795
00:29:33,961 --> 00:29:34,895
PARTNERSHIPS AND AI AND WE WANT

796
00:29:34,895 --> 00:29:37,865
TO USE THIS TO OPEN UP

797
00:29:37,865 --> 00:29:39,767
OPPORTUNITIES LIKE REALTIME

798
00:29:39,767 --> 00:29:42,336
HEALTH MONITORING, DRUG

799
00:29:42,336 --> 00:29:42,770
DEVELOPMENT, LINKING

800
00:29:42,770 --> 00:29:44,004
LONGITUDINAL DATA SETS AND

801
00:29:44,004 --> 00:29:45,606
IMPROVING OUR ABILITY TO ADDRESS

802
00:29:45,606 --> 00:29:48,709
PUBLIC HEALTH CRISIS AND IMPROVE

803
00:29:48,709 --> 00:29:49,610
PUBLIC HEALTH PROTECTION.

804
00:29:49,610 --> 00:29:52,045
AI CAN ALSO BE USED AS A TOOL TO

805
00:29:52,045 --> 00:29:54,681
SUPPORT NEW APPROACHES IN HUMAN

806
00:29:54,681 --> 00:29:56,483
ENVIRONMENTAL SAFETY ASSESSMENTS

807
00:29:56,483 --> 00:29:59,787
AND IN DRUG DISCOVERY, DRUG

808
00:29:59,787 --> 00:30:00,821
DEVELOPMENT AND MECHANISTIC

809
00:30:00,821 --> 00:30:02,890
INSIGHT INTO YEEN AND HEALTH

810
00:30:02,890 --> 00:30:04,124
DISEASE PATHWAYS, WE ANNOUNCED A

811
00:30:04,124 --> 00:30:06,293
92 YOU INITIATIVE AT THE END OF

812
00:30:06,293 --> 00:30:08,629
APRIL, ON APRIL 29th, NIH

813
00:30:08,629 --> 00:30:10,798
ANNOUNCED SORT OF A RENEWED

814
00:30:10,798 --> 00:30:11,832
COMMITMENT TO DEVELOPING

815
00:30:11,832 --> 00:30:13,233
VALIDATING AND SCALING THE USE

816
00:30:13,233 --> 00:30:16,236
OF NEW APPROACH METHODS ACROSS

817
00:30:16,236 --> 00:30:20,874
THE AGENCIES BIOMEDICAL RESEARCH

818
00:30:20,874 --> 00:30:21,141
PORTFOLIO.

819
00:30:21,141 --> 00:30:23,443
SO THESE ARE LAB OR COMPUTER

820
00:30:23,443 --> 00:30:25,012
PAITIONED TECHNIQUES THAT ARE

821
00:30:25,012 --> 00:30:26,880
DESIGNED TO MORE ACALATELY MODEL

822
00:30:26,880 --> 00:30:28,982
HUMAN BIOLOGY, SERVE AS A

823
00:30:28,982 --> 00:30:30,851
COMPLIMENTARY APPROACH TO

824
00:30:30,851 --> 00:30:31,618
TRADITIONAL ANIMAL STUDIES AND

825
00:30:31,618 --> 00:30:33,720
YOU KNOW IN SOME CASES WHERE THE

826
00:30:33,720 --> 00:30:35,923
SCIENCE IS READY SERVE AS

827
00:30:35,923 --> 00:30:38,091
ALTERNATIVES TO ANIMAL TESTING.

828
00:30:38,091 --> 00:30:40,360
BUT REALLY TRY AND LEVERAGE THE

829
00:30:40,360 --> 00:30:44,097
FULL TOOL BOX THAT WE HAVE FOR

830
00:30:44,097 --> 00:30:45,499
RESEARCHERS TO ANSWER VERY

831
00:30:45,499 --> 00:30:47,668
DIFFICULT BIOMEDICAL RESEARCH

832
00:30:47,668 --> 00:30:47,935
QUESTIONS.

833
00:30:47,935 --> 00:30:49,970
AGAIN, THIS IS NOT SOMETHING

834
00:30:49,970 --> 00:30:51,638
THAT'S BRAND NEW, NIH

835
00:30:51,638 --> 00:30:53,407
INVESTMENTS, YOU KNOW ARE WIDE

836
00:30:53,407 --> 00:30:56,243
SPREAD ACROSS THE DIFFERENT

837
00:30:56,243 --> 00:30:59,813
ICs, AND WE HAVE EXISTING

838
00:30:59,813 --> 00:31:02,449
EFFORTS LIKE ICVAAM, THAT I USED

839
00:31:02,449 --> 00:31:04,718
TO DIRECT, THE TISSUE PROGRAM

840
00:31:04,718 --> 00:31:06,553
UNDER NCATS OTHERS ORGANOID

841
00:31:06,553 --> 00:31:09,223
MODELS BUILT ACROSS THE ENTIRE

842
00:31:09,223 --> 00:31:09,923
INTRAMURAL RESEARCH PROGRAM MANY

843
00:31:09,923 --> 00:31:12,759
OF WHICH ARE SPECIFIC TO WOMEN'S

844
00:31:12,759 --> 00:31:15,395
HEALTH AND THEN WE HAVE OTHER

845
00:31:15,395 --> 00:31:22,970
GRANTING PROGRAMS LIKE THE NEW

846
00:31:22,970 --> 00:31:24,838
COMPLEMENT-ARIE AND AN RESEARCH

847
00:31:24,838 --> 00:31:26,173
IN EXPERIMENTATION PROGRAM THAT

848
00:31:26,173 --> 00:31:28,642
ARE GETTING READY TO MAKE AWARDS

849
00:31:28,642 --> 00:31:29,076
NOW.

850
00:31:29,076 --> 00:31:31,144
EXPANDING ONGOING EFFORTS AS

851
00:31:31,144 --> 00:31:34,348
PART OF THIS INITIATIVE, NIH

852
00:31:34,348 --> 00:31:35,849
PLANS TO COORDINATE, VALIDATE

853
00:31:35,849 --> 00:31:38,919
AND SCALE THESE HUMAN BASED

854
00:31:38,919 --> 00:31:40,287
RESEARCH METHODS AND KIND OF

855
00:31:40,287 --> 00:31:44,324
SERVE AS I HUB BOTH WITHIN THE

856
00:31:44,324 --> 00:31:46,393
NIH TO COORDINATE ACROSS THE

857
00:31:46,393 --> 00:31:47,861
VARIOUS EFFORTS, ACROSS ICOs

858
00:31:47,861 --> 00:31:49,796
BUT ALSO ACROSS THE FEDERAL

859
00:31:49,796 --> 00:31:50,964
GOVERNMENT AND ACROSS THE

860
00:31:50,964 --> 00:31:53,166
SCIENTIFIC LANDSCAPE AND EXPAND

861
00:31:53,166 --> 00:31:55,235
FUNDING AND TRAINING FOR THESE

862
00:31:55,235 --> 00:31:59,172
HUMAN BASED APPROACHES AND

863
00:31:59,172 --> 00:32:01,141
EXPAND THE INFRASTRUCTURE TO

864
00:32:01,141 --> 00:32:02,776
CONTINUE TO IMPROVE BOTH THE

865
00:32:02,776 --> 00:32:04,077
ACCESSIBILITY AND RELEVANCE TO

866
00:32:04,077 --> 00:32:07,447
CRITICAL HUMAN HEALTH QUESTIONS

867
00:32:07,447 --> 00:32:09,583
AND ALSO, KIND OF UPDATE HOW

868
00:32:09,583 --> 00:32:12,452
GRANT ARE BEING REVIEWED TO

869
00:32:12,452 --> 00:32:13,854
INTEGRATE MORE CUTTING EDGE

870
00:32:13,854 --> 00:32:17,357
HUMAN BIOLOGY BASED METHODS INTO

871
00:32:17,357 --> 00:32:20,093
CONSIDERATION AND REVIEW PANELS

872
00:32:20,093 --> 00:32:22,062
AND STUDY SECTIONS SO WE'RE ALL

873
00:32:22,062 --> 00:32:23,563
VERY EXCITED ABOUT NIH'S

874
00:32:23,563 --> 00:32:24,965
COMMITMENT TO EXPAND AND FURTHER

875
00:32:24,965 --> 00:32:28,068
INTEGRATE THESE HUMAN BASED

876
00:32:28,068 --> 00:32:29,770
RESEARCH TECHNOLOGIES.

877
00:32:29,770 --> 00:32:32,039
WE ALSO RECOGNIZE THAT IT'S VERY

878
00:32:32,039 --> 00:32:34,508
IMPORTANT TO BE THOUGHTFUL AND

879
00:32:34,508 --> 00:32:36,243
TO BE GOOD STEWARDS OF SORT OF

880
00:32:36,243 --> 00:32:39,646
HOW WE ARE USING NEW

881
00:32:39,646 --> 00:32:42,849
TECHNOLOGIES AND THAT THERE ARE

882
00:32:42,849 --> 00:32:44,952
RISKS TO APPLY THINGS LIKE AI IF

883
00:32:44,952 --> 00:32:46,520
THEY ARE IMPROPERLY TRAINED OR

884
00:32:46,520 --> 00:32:47,321
CONTROLLED OR APPLIED.

885
00:32:47,321 --> 00:32:50,924
SO WE HAVE 2 RFIs, OUT RIGHT

886
00:32:50,924 --> 00:32:53,827
NOW, THE FIRST IS ON RESPONSIBLY

887
00:32:53,827 --> 00:32:56,330
DEVELOPING AND SHARING

888
00:32:56,330 --> 00:32:57,130
GENERATIVE ARTIFICIAL

889
00:32:57,130 --> 00:32:58,966
INTELLIGENCE TOOLS USING NIH

890
00:32:58,966 --> 00:33:00,867
CONTROLLED ACCESS DATA THAT'S ON

891
00:33:00,867 --> 00:33:02,703
THE BOTTOM OF THE SLIDE THERE.

892
00:33:02,703 --> 00:33:04,471
IT WAS RELEASEDDA THE END OF MAY

893
00:33:04,471 --> 00:33:08,942
AND THE RESPONSE DATE IS

894
00:33:08,942 --> 00:33:10,911
JULY 16th, AND THEN ALSO

895
00:33:10,911 --> 00:33:14,982
INVITING COMMENTS ON NIH

896
00:33:14,982 --> 00:33:15,682
ARTIFICIAL INTELLIGENCE STRATEGY

897
00:33:15,682 --> 00:33:17,651
ON THEMES AND PILLARS AND

898
00:33:17,651 --> 00:33:18,785
SPECIFIC ACTIONS THAT COULD

899
00:33:18,785 --> 00:33:21,455
SHAPE THE FORTH COMING NIH AI

900
00:33:21,455 --> 00:33:24,591
STRATEGIC PLAN. 

901
00:33:24,591 --> 00:33:27,494
BOTH OF THOSE RFIs CLOSE IN

902
00:33:27,494 --> 00:33:28,662
JULY, SO PLEASE SCAN THE QR

903
00:33:28,662 --> 00:33:30,831
CODES ON THE SCREENS AND FIND

904
00:33:30,831 --> 00:33:32,032
MORE INFORMATION AND DISSEMINATE

905
00:33:32,032 --> 00:33:33,567
THEM AMONG YOUR NETWORKS

906
00:33:33,567 --> 00:33:34,935
BROADLY, WE REALLY WANT TO A

907
00:33:34,935 --> 00:33:38,405
ROBUST RESPONSE TO THESE RFIs.

908
00:33:38,405 --> 00:33:43,310
SO INTEGRATING TECHNOLOGY AND

909
00:33:43,310 --> 00:33:45,178
FOSTERING INNOVATION ARE PIVOTAL

910
00:33:45,178 --> 00:33:47,080
IN ADVANCING WOMEN'S HEALTH

911
00:33:47,080 --> 00:33:48,415
RESEARCH AND I THINK THAT A LOT

912
00:33:48,415 --> 00:33:49,816
OF THE EMERGING TOOLS WE HAVE

913
00:33:49,816 --> 00:33:52,185
AVAILABLE TO US, LIKE DIGITAL

914
00:33:52,185 --> 00:33:54,421
PLATFORMS OR WEARABLE SENSORS,

915
00:33:54,421 --> 00:33:56,490
ADVANCING ANALYTICS, THEY ALL

916
00:33:56,490 --> 00:33:58,225
REALLY ENABLED MORE PRECISE AND

917
00:33:58,225 --> 00:33:59,192
PERSONALIZED AND REALTIME

918
00:33:59,192 --> 00:34:02,295
INSIGHTS INTO CONDITIONS THAT

919
00:34:02,295 --> 00:34:02,963
DISPROPORTIONATELY AFFECT WOMEN.

920
00:34:02,963 --> 00:34:05,032
SO, YOU KNOW WE CAN LEVERAGE

921
00:34:05,032 --> 00:34:07,334
THESE INNOVATIONS AND THESE NEW

922
00:34:07,334 --> 00:34:09,836
TECHNOLOGIES TO UNCOVER

923
00:34:09,836 --> 00:34:11,505
SEX-SPECIFIC DISEASE MECHANISMS,

924
00:34:11,505 --> 00:34:13,807
AND CLOSE GAPS IN HEALTH AND

925
00:34:13,807 --> 00:34:16,176
DEVELOP MORE EFFECTIVE

926
00:34:16,176 --> 00:34:16,543
INTERVENTIONS.

927
00:34:16,543 --> 00:34:19,012
I THINK THAT EMBRACING

928
00:34:19,012 --> 00:34:21,882
TECHNOLOGY NOT ONLY ACCELERATES

929
00:34:21,882 --> 00:34:23,550
DISCOVERY, BUT IT INSURES THAT

930
00:34:23,550 --> 00:34:25,619
WOMEN'S HEALTH NEEDS ARE

931
00:34:25,619 --> 00:34:27,454
ADDRESSED WITH THE RIGOR AND

932
00:34:27,454 --> 00:34:28,955
URGENCY THAT THEY DESERVE AND

933
00:34:28,955 --> 00:34:31,958
SO, YOU KNOW NIH IT REALLY HOLDS

934
00:34:31,958 --> 00:34:34,027
IT AT THE FOREFRONT OFAUR MINDS

935
00:34:34,027 --> 00:34:35,996
AND WE'RE IMPLEMENTING SEVERAL

936
00:34:35,996 --> 00:34:39,132
INITIATIVES TO HARNESS THE

937
00:34:39,132 --> 00:34:42,903
TECHNOLOGICAL ADD VANCES WOMEN'S

938
00:34:42,903 --> 00:34:43,970
HEALTH RESEARCH SPECIFICALLY.

939
00:34:43,970 --> 00:34:49,042
ONE IS UNDER THE RAD-X PROGRAM,

940
00:34:49,042 --> 00:34:53,246
IS ADVANCING TOURS AND

941
00:34:53,246 --> 00:34:58,518
FURTHERING THERAPIES AND ENDING

942
00:34:58,518 --> 00:34:59,953
ENDOMEET RIOSEIS DIAGNOSTIC

943
00:34:59,953 --> 00:35:02,756
DELAYS OR ACT ENDO, CHALLENGE,

944
00:35:02,756 --> 00:35:07,894
THIS IS OFTEN A DEBIL TIGHTING

945
00:35:07,894 --> 00:35:09,062
GYNECOLOGICAL DISEASE, NIH

946
00:35:09,062 --> 00:35:12,466
SELECTED 4 WINNERS FOR THIS

947
00:35:12,466 --> 00:35:17,737
COMPETITION, FOR THE

948
00:35:17,737 --> 00:35:18,972
ENDOMETRIOSIS TECHNOLOGIES, AND

949
00:35:18,972 --> 00:35:22,776
THIS IS FOR VARIOUS FORMS OF

950
00:35:22,776 --> 00:35:24,244
IMAGING, ANOTHER CHALLENGE

951
00:35:24,244 --> 00:35:25,779
COMPETITION IS CALLED DEBUT AND

952
00:35:25,779 --> 00:35:27,481
IT'S BEEN GOING ON SINCE 2013

953
00:35:27,481 --> 00:35:30,484
AND THIS HAS A REAL CAREER

954
00:35:30,484 --> 00:35:31,985
DEVELOPMENT ASPECT TO IT BECAUSE

955
00:35:31,985 --> 00:35:33,854
IT FOCUSES ON JUNIOR

956
00:35:33,854 --> 00:35:36,256
RESEARCHERS, SO CHALLENGES USHED

957
00:35:36,256 --> 00:35:37,891
GRADUATES, STUDENTS TO DEVELOP

958
00:35:37,891 --> 00:35:39,826
TECHNOLOGICAL NEEDS IN SOLUTIONS

959
00:35:39,826 --> 00:35:44,598
TO ANY UNMEET AREA OF NEED IN

960
00:35:44,598 --> 00:35:44,931
HEALTHCARE.

961
00:35:44,931 --> 00:35:49,436
AND IN 2024, THERE WERE QUITE A

962
00:35:49,436 --> 00:35:51,872
FEW AWARDS ACROSS TOPICS

963
00:35:51,872 --> 00:35:53,140
INCLUDING KEY ADVANCEMENTS IN

964
00:35:53,140 --> 00:35:57,010
WOMEN'S HEALTH, A VAGINAL SPEC

965
00:35:57,010 --> 00:35:58,979
LUMTHAT PROVIDES GREATER

966
00:35:58,979 --> 00:36:02,616
FUNCTIONALITY, AND MRI THAT

967
00:36:02,616 --> 00:36:03,783
STREAMLINES THE MRI BREAST

968
00:36:03,783 --> 00:36:06,686
PROCESS, SO BY ADVANCING

969
00:36:06,686 --> 00:36:08,421
TECHNOLOGICAL ADVANCES NIH PLANS

970
00:36:08,421 --> 00:36:09,156
TO REVOLUTIONIZE WOMEN'S

971
00:36:09,156 --> 00:36:10,724
RESEARCH AND LEAD TO MORE

972
00:36:10,724 --> 00:36:11,691
INTERVENTIONS AND IMPROVED

973
00:36:11,691 --> 00:36:13,226
HEALTH OUTCOMES FOR WOMEN ACROSS

974
00:36:13,226 --> 00:36:13,660
THEIR LIFE SPAN.

975
00:36:13,660 --> 00:36:19,666
SO THANK YOU SO MUCH FOR

976
00:36:19,666 --> 00:36:20,600
ALLOWING ME THE OPPORTUNITY ON

977
00:36:20,600 --> 00:36:21,535
SPEAK TO YOU TODAY.

978
00:36:21,535 --> 00:36:22,969
I DO HAVE TIME TO ANSWER ANY

979
00:36:22,969 --> 00:36:25,272
QUESTIONS AND THANK YOU AGAIN TO

980
00:36:25,272 --> 00:36:29,342
DR. CLAYTON AND DR. OTA WANG AND

981
00:36:29,342 --> 00:36:33,813
ORWH AND ALL OF YOU FOR HAVING

982
00:36:33,813 --> 00:36:34,347
ME HERE TODAY.

983
00:36:34,347 --> 00:36:35,649
>> THANK YOU SO MUCH FOR
SHARING

984
00:36:35,649 --> 00:36:37,217
YOUR VISION AND YOUR BACKGROUND

985
00:36:37,217 --> 00:36:39,986
AND I'M SURE EVERYONE IS VERY

986
00:36:39,986 --> 00:36:41,788
EXCITED TO HEAR ABOUT YOUR

987
00:36:41,788 --> 00:36:45,258
INTEREST IN WOMEN'S HEALTH AND

988
00:36:45,258 --> 00:36:48,862
AND WE ARE EXCITED TO BRING

989
00:36:48,862 --> 00:36:51,064
WOMEN'S HEALTH TO THE NOW WORLD

990
00:36:51,064 --> 00:36:52,465
AS YOU HIGHLIGHTED THE TRUE

991
00:36:52,465 --> 00:36:55,402
OPPORTUNITY AND POTENTIAL THERE.

992
00:36:55,402 --> 00:36:56,703
DR. OTAWANG DO WE HAVE QUESTIONS

993
00:36:56,703 --> 00:37:05,946
IN THE ROOM FOR

994
00:37:05,946 --> 00:37:06,346
DR. KLEINSTREUER?

995
00:37:06,346 --> 00:37:06,746
>> I'M LOOKING.

996
00:37:06,746 --> 00:37:08,148
>> VIVIAN I THINK THERE IS
A

997
00:37:08,148 --> 00:37:12,786
QUESTION FROM DR. JONES ONLINE?

998
00:37:12,786 --> 00:37:14,955
>> HI, CAN EVERYBODY HEAR
ME?

999
00:37:14,955 --> 00:37:17,290
THANK YOU.

1000
00:37:17,290 --> 00:37:22,362
THANK YOU DR. KLEINSTREUER,

1001
00:37:22,362 --> 00:37:24,331
THANK YOU FOR THE WONDERFUL

1002
00:37:24,331 --> 00:37:25,699
PRESENTATION, I LEARNED A LOT

1003
00:37:25,699 --> 00:37:26,900
AND IT'S VERY EXCITING.

1004
00:37:26,900 --> 00:37:31,304
I WONDER IF YOU COULD COMMENT ON

1005
00:37:31,304 --> 00:37:33,306
THE SEX IN WOMEN AND ADDICTION

1006
00:37:33,306 --> 00:37:34,007
AND PARTICULARLY OPIOIDS BECAUSE

1007
00:37:34,007 --> 00:37:37,978
WE KNOW THAT WHILE OUR OPIOID

1008
00:37:37,978 --> 00:37:39,279
OVERDOSE DEATHS ARE GOING DOWN,

1009
00:37:39,279 --> 00:37:43,016
WE STILL ARE DEALING WITH THIS

1010
00:37:43,016 --> 00:37:43,850
CRISIS AS AMERICANS, SO ANYTHING

1011
00:37:43,850 --> 00:37:45,352
YOU WILL LIKE TO SAY ABOUT THAT,

1012
00:37:45,352 --> 00:37:46,720
I WOULD APPRECIATE LEARNING FROM

1013
00:37:46,720 --> 00:37:48,088
YOU, THANK YOU.

1014
00:37:48,088 --> 00:37:50,724
>> WELL, THANK YOU FOR THE

1015
00:37:50,724 --> 00:37:51,491
QUESTION DR. JONES.

1016
00:37:51,491 --> 00:37:53,927
I AM GOING TO PREFACE MY

1017
00:37:53,927 --> 00:37:55,762
RESPONSE WITH SAYING THAT IS NOT

1018
00:37:55,762 --> 00:37:59,432
MY AREA OF EXPERTISE, I THINK

1019
00:37:59,432 --> 00:38:00,834
IT'S AN INCREDIBLE LOAMACYY

1020
00:38:00,834 --> 00:38:02,235
IMPORTANT RESEARCH TOPIC, AS YOU

1021
00:38:02,235 --> 00:38:04,070
HIGHLIGHTED THERE ARE CLEAR SEX

1022
00:38:04,070 --> 00:38:05,772
DIFFERENCES IN ADDICTION AND

1023
00:38:05,772 --> 00:38:09,075
SORT OF BEHAVIORS THAT INFLUENCE

1024
00:38:09,075 --> 00:38:09,576
ADDICTION.

1025
00:38:09,576 --> 00:38:11,044
I WOULD ACTUALLY ASK DR. CLAYTON

1026
00:38:11,044 --> 00:38:16,116
IF SHE COULD HELP BACK  ME UP ON

1027
00:38:16,116 --> 00:38:16,750
THIS ANSWER HERE.

1028
00:38:16,750 --> 00:38:18,918
MY UNDERSTAND SUGGEST THAT THERE

1029
00:38:18,918 --> 00:38:20,420
IS INTERACTION WITH THE NATIONAL

1030
00:38:20,420 --> 00:38:22,522
INSTITUTE ON DRUG ABUSE, THE

1031
00:38:22,522 --> 00:38:24,591
NATIONAL INSTITUTE ON ALCOHOL,

1032
00:38:24,591 --> 00:38:29,663
SO NIAAA, AT NIDA AND NIMH ARE

1033
00:38:29,663 --> 00:38:32,766
STRONG PARTNERS FOR ORWH, AND

1034
00:38:32,766 --> 00:38:34,434
JANINE IF YOU COULD PROVIDE MORE

1035
00:38:34,434 --> 00:38:35,368
SPECIFICS ABOUT ACTIVITY IN THAT

1036
00:38:35,368 --> 00:38:36,636
AREA, I WOULD BE VALID AND

1037
00:38:36,636 --> 00:38:37,270
RELIABLE GRATEFUL BECAUSE I

1038
00:38:37,270 --> 00:38:39,873
WOULD LIKE TO LEARN AS WELL.

1039
00:38:39,873 --> 00:38:42,142
>> SURE, SURE.

1040
00:38:42,142 --> 00:38:43,176
DR. JONES, FANTASTIC QUESTION,

1041
00:38:43,176 --> 00:38:45,011
SEX DIFFERENCES IN SUBSTANCE USE

1042
00:38:45,011 --> 00:38:46,646
HAVE BEEN A LONG-TERM INTEREST

1043
00:38:46,646 --> 00:38:49,749
OF ORWH AND WE HAVE A FANTASTIC

1044
00:38:49,749 --> 00:38:51,918
COLLABORATIVE RELATIONSHIP WITH

1045
00:38:51,918 --> 00:38:54,587
NIDA, AND NIMH AND NIAAA, AND

1046
00:38:54,587 --> 00:38:55,989
WE'RE ALSO CONCERNED ABOUT

1047
00:38:55,989 --> 00:38:57,057
INCREASING RATES OF ALCOHOL USE

1048
00:38:57,057 --> 00:38:58,391
AND THE CONQUENCES BECAUSE WE

1049
00:38:58,391 --> 00:39:01,428
KNOW THAT WOMEN TEND TO HAVE

1050
00:39:01,428 --> 00:39:03,730
ACCELERATED CONSEQUENCES FROM

1051
00:39:03,730 --> 00:39:06,032
ALCOHOL USE IN TERMS OF MEN IN

1052
00:39:06,032 --> 00:39:07,534
TERMS OF MULTIORGAN ISSUES.

1053
00:39:07,534 --> 00:39:10,003
SO IN ADDITION TO NIDA

1054
00:39:10,003 --> 00:39:11,438
COLLABORATING WITH ORWH ON THE

1055
00:39:11,438 --> 00:39:14,174
SCORE, THE CENTERS FOR RESEARCH

1056
00:39:14,174 --> 00:39:16,710
EXCELLENCE ON SEX DIFFERENCES

1057
00:39:16,710 --> 00:39:18,511
WHERE THEY HAVE FUNDED FOR MANY

1058
00:39:18,511 --> 00:39:21,047
YEARS WITH US LOOKING AT SEX

1059
00:39:21,047 --> 00:39:23,249
DIFFERENCES IN MULTIPLE

1060
00:39:23,249 --> 00:39:24,084
SUBSTANCE DISUSE DISORDERS, WE

1061
00:39:24,084 --> 00:39:26,052
CONTINUE TO WORK CLOSELY WITH

1062
00:39:26,052 --> 00:39:27,654
THEM IN TERMS OF RESEARCH

1063
00:39:27,654 --> 00:39:28,955
PRIORITIES AND SEVERAL OF THESE

1064
00:39:28,955 --> 00:39:30,924
INSTITUTE VS ISSUED THEIR OWN

1065
00:39:30,924 --> 00:39:32,625
FUNDING OPPORTUNITY AKNOWNST

1066
00:39:32,625 --> 00:39:33,827
WANTS RELATED TO SEX DIFFERENCES

1067
00:39:33,827 --> 00:39:35,061
IN THEIR MISSION AREAS.

1068
00:39:35,061 --> 00:39:39,065
SO I ASSURE YOU THIS REMAINS OF

1069
00:39:39,065 --> 00:39:39,666
INTEREST TO EVERYONE.

1070
00:39:39,666 --> 00:39:41,267
DRIVING IN THIS MORNING I HEARD

1071
00:39:41,267 --> 00:39:42,669
ABOUT THE DECREASING RATES OF

1072
00:39:42,669 --> 00:39:44,337
OVERDOSE DEATH AND I THINK THAT

1073
00:39:44,337 --> 00:39:45,705
THAT'S A FANTASTIC EXAMPLE OF

1074
00:39:45,705 --> 00:39:47,974
THE WAY THAT WHEN WE PUT OUR

1075
00:39:47,974 --> 00:39:50,009
FORCES TOGETHER, AND I'M SURE,

1076
00:39:50,009 --> 00:39:56,383
NICOLE WILL  AAGREE, KIND OF A

1077
00:39:56,383 --> 00:39:56,983
CROSS GOVERNMENT APPROACH, WE

1078
00:39:56,983 --> 00:39:58,852
CAN WHEN WE UNDERSTAND THESE SEX

1079
00:39:58,852 --> 00:40:00,253
DIFFERENCES WE CAN IMPLEMENT

1080
00:40:00,253 --> 00:40:04,057
STRATEGIES THAT WORK FOR WOMEN

1081
00:40:04,057 --> 00:40:04,491
AND MEN.

1082
00:40:04,491 --> 00:40:07,427
>> THANK YOU SO MUCH.

1083
00:40:07,427 --> 00:40:08,695
>> ABSOLUTELY.

1084
00:40:08,695 --> 00:40:09,129
ABSOLUTELY.

1085
00:40:09,129 --> 00:40:09,529
>> DR. HIGGINS?

1086
00:40:09,529 --> 00:40:10,997
>> AND THEN I WILL TURN IT
OVER

1087
00:40:10,997 --> 00:40:11,931
TO YOU VIVIAN.

1088
00:40:11,931 --> 00:40:12,632
>> YEAH, THANKS FOR THIS

1089
00:40:12,632 --> 00:40:16,002
OPPORTUNITY TO ASK A QUESTION.

1090
00:40:16,002 --> 00:40:17,737
AND LIKE DR. JONES JUST SAID, I

1091
00:40:17,737 --> 00:40:19,939
LEARNED A LOT FROM THE

1092
00:40:19,939 --> 00:40:20,306
PRESENTATION.

1093
00:40:20,306 --> 00:40:24,911
SO MY QUESTION, I'M AN ADDICTION

1094
00:40:24,911 --> 00:40:26,846
SCIENTIST, I FOCUS MORE ON

1095
00:40:26,846 --> 00:40:29,716
TOBACCO THAN OPIOIDS BUT THEY --

1096
00:40:29,716 --> 00:40:32,085
TOBACCO WAS HAVING A

1097
00:40:32,085 --> 00:40:33,019
DISPROPORTIONATE IMPACT ON THE

1098
00:40:33,019 --> 00:40:36,956
HEALTH OF RURAL WOMEN, LARGELY

1099
00:40:36,956 --> 00:40:38,792
BECAUSE IT'S HARD ON BRING

1100
00:40:38,792 --> 00:40:39,626
EVIDENCE-BASED TREATMENT TO

1101
00:40:39,626 --> 00:40:40,093
THEM.

1102
00:40:40,093 --> 00:40:41,928
WE'RE VERY INTERESTED IN YOU

1103
00:40:41,928 --> 00:40:43,997
KNOW DOING -- DEVELOPING DIGITAL

1104
00:40:43,997 --> 00:40:44,697
INTERVENTIONS THAT CAN REACH

1105
00:40:44,697 --> 00:40:47,534
THEM BUT I WAS JUST CURIOUS HOW

1106
00:40:47,534 --> 00:40:57,911
YOU THINK ABOUT RURAL

1107
00:41:00,246 --> 00:41:00,613
DISPARITIES?

1108
00:41:00,613 --> 00:41:02,282
>> THAT'S A GREAT QUESTION
AND

1109
00:41:02,282 --> 00:41:04,617
YOU MAY OR MAY NOT BE AWARE OF

1110
00:41:04,617 --> 00:41:06,853
OUR CARE FOR HEALTH PROGRAM, IT

1111
00:41:06,853 --> 00:41:08,054
WAS FAIRLY NASCENT, IT'S JUST

1112
00:41:08,054 --> 00:41:09,756
BEEN LAUNCHED LAST YEAR.

1113
00:41:09,756 --> 00:41:12,425
IT IS SETTING UP A NETWORK OF

1114
00:41:12,425 --> 00:41:14,160
PRIMARY CARE PROVIDERS THAT CAN

1115
00:41:14,160 --> 00:41:18,231
BE USED FOR DECENTRALIZED

1116
00:41:18,231 --> 00:41:21,134
CLINICAL TRIALS AND IMPLEMENTING

1117
00:41:21,134 --> 00:41:22,669
AND ASKING RESEARCH QUESTIONS

1118
00:41:22,669 --> 00:41:24,604
THROUGH THESE PRIMARY CARE

1119
00:41:24,604 --> 00:41:25,672
PROVIDER NETWORKS AND THE VAST

1120
00:41:25,672 --> 00:41:28,908
MAJORITY OF THEM ARE LOCATED IN

1121
00:41:28,908 --> 00:41:30,210
RURAL COMMUNITIES TO ACTUALLY

1122
00:41:30,210 --> 00:41:32,278
ADDRESS EXACTLY THE ISSUES THAT

1123
00:41:32,278 --> 00:41:37,750
YOU'VE RAISED IN TERMS OF

1124
00:41:37,750 --> 00:41:38,451
DISPROPORTIONATE AFFECTS ON

1125
00:41:38,451 --> 00:41:39,853
FOLKS THAT LIVE IN RURAL AREAS

1126
00:41:39,853 --> 00:41:42,722
THAT MAY HAVE LOWER OR ALMOST

1127
00:41:42,722 --> 00:41:44,390
NONEXISTENT READY ACCESS TO HIGH

1128
00:41:44,390 --> 00:41:47,160
QUALITY HEALTHCARE AND SO, THEIR

1129
00:41:47,160 --> 00:41:49,095
CARE FOR HEALTH IS IN THE STAGE

1130
00:41:49,095 --> 00:41:54,267
RIGHT NOW OF REVIEWING A NUMBER

1131
00:41:54,267 --> 00:41:57,403
OF CLINICAL TRIAL STUDY CONCEPT

1132
00:41:57,403 --> 00:41:58,338
PROPOSALS AND I WILL FOLLOW UP

1133
00:41:58,338 --> 00:41:59,539
WITH THIS AND I WILL BE

1134
00:41:59,539 --> 00:42:01,174
INTERESTED TO SEE IF ANY OF THEM

1135
00:42:01,174 --> 00:42:02,675
ARE ACTUALLY SPECIFICALLY

1136
00:42:02,675 --> 00:42:07,280
ADDRESSING, YOU KNOW TOBACCO USE

1137
00:42:07,280 --> 00:42:08,214
IN VARIOUS FORMS FROM SMOKING

1138
00:42:08,214 --> 00:42:11,584
ALL THE WAY TO VAPING AS WELL.

1139
00:42:11,584 --> 00:42:13,520
I THINK ALSO, I'M SURE YOU'RE

1140
00:42:13,520 --> 00:42:16,022
FAMILIAR WITH THE TOBACCO

1141
00:42:16,022 --> 00:42:17,757
REGULATORY SCIENCE PROGRAM WHICH

1142
00:42:17,757 --> 00:42:19,259
IS AN INTERAGENCY PARTNERSHIP

1143
00:42:19,259 --> 00:42:22,028
BETWEEN THE NIH AND THE FDA

1144
00:42:22,028 --> 00:42:24,631
CENTER FOR TOBACCO PRODUCTS THAT

1145
00:42:24,631 --> 00:42:26,766
I KNOW THEY'VE HAD SOME PROJECTS

1146
00:42:26,766 --> 00:42:28,902
THAT HAVE FOCUSED ON RURAL

1147
00:42:28,902 --> 00:42:30,403
COMMUNITIES, TOO, SO IT WOULD

1148
00:42:30,403 --> 00:42:32,906
ALSO, I CAN FOLLOW UP WITH THEM

1149
00:42:32,906 --> 00:42:36,509
ON SORT OF THE INCLUSION OF SEX

1150
00:42:36,509 --> 00:42:38,411
DIFFERENCES IN THOSE RESEARCH

1151
00:42:38,411 --> 00:42:38,912
QUESTIONS AND OUTCOMES.

1152
00:42:38,912 --> 00:42:41,214
SO THANK YOU FOR RAISING THAT.

1153
00:42:41,214 --> 00:42:41,781
>> YEAH, THANK YOU.

1154
00:42:41,781 --> 00:42:43,516
I DIDN'T KNOW ABOUT THE CARES

1155
00:42:43,516 --> 00:42:46,019
PROGRAM SO I WILL LOOK IT UP AND

1156
00:42:46,019 --> 00:42:47,186
LEARN MORE ABOUT IT.

1157
00:42:47,186 --> 00:42:48,121
THANK YOU.

1158
00:42:48,121 --> 00:42:48,721
CARE FOR HEALTH.

1159
00:42:48,721 --> 00:42:50,857
>> CARE FOR HEALTH IS THE
NAME.

1160
00:42:50,857 --> 00:42:52,191
>> YES, CARE FOR HEALTH.

1161
00:42:52,191 --> 00:42:53,560
>> AND DR. HIGGINS YOU
WILL HEAR

1162
00:42:53,560 --> 00:42:55,295
A BIT IN MY PRESENTATION ABOUT

1163
00:42:55,295 --> 00:42:56,696
THE EXPANSION OF THE IDEA STATES

1164
00:42:56,696 --> 00:42:58,765
PROGRAM TO ADDRESS WOMEN'S

1165
00:42:58,765 --> 00:43:00,600
HEALTH AND OUR CENTERS OF

1166
00:43:00,600 --> 00:43:02,569
BIOMEDICAL RESEARCH EXCELLENCE

1167
00:43:02,569 --> 00:43:04,671
ON WOMEN'S HEALTH, COBREs,

1168
00:43:04,671 --> 00:43:07,774
THERE IS 1 WE'RE FUNDING WITH

1169
00:43:07,774 --> 00:43:09,142
NIGMS LOCATED AT THE UNIVERSITY

1170
00:43:09,142 --> 00:43:12,278
OF KANSAS AND THEY ARE LOOKING

1171
00:43:12,278 --> 00:43:13,646
SPECIFICALLY AT TELEHEALTH

1172
00:43:13,646 --> 00:43:15,515
MEDICINE INTERVENTIONS FOR RURAL

1173
00:43:15,515 --> 00:43:16,015
LOCATIONS.

1174
00:43:16,015 --> 00:43:17,317
SO WE'RE KEENLY AWARE OF THE

1175
00:43:17,317 --> 00:43:19,752
UNIQUE NEEDS OF WOMEN IN RURAL

1176
00:43:19,752 --> 00:43:21,421
LOCATIONS AND THOSE GEOGRAPHIC

1177
00:43:21,421 --> 00:43:22,288
DIFFERENCES ARE IMPORTANT SO WE

1178
00:43:22,288 --> 00:43:23,890
CAN ADDRESS THE NEEDS OF ALL

1179
00:43:23,890 --> 00:43:34,334
WOMEN ACROSS THE COUNTRY.

1180
00:43:36,603 --> 00:43:37,704
>> THANK YOU.

1181
00:43:37,704 --> 00:43:39,038
>> WELL, THANK YOU AGAIN
SO MUCH

1182
00:43:39,038 --> 00:43:40,940
FOR HAVING ME.

1183
00:43:40,940 --> 00:43:41,774
I REALLY, REALLY APPRECIATE IT,

1184
00:43:41,774 --> 00:43:43,343
AND I HAVE TO APOLOGIZE THAT I

1185
00:43:43,343 --> 00:43:45,645
HAVE TO GO BOARD A PLANE, SO

1186
00:43:45,645 --> 00:43:47,146
UNFORTUNATELY I'M NOT GOING TO

1187
00:43:47,146 --> 00:43:50,416
BE ABLE TO AT A FOR THE REST,

1188
00:43:50,416 --> 00:43:52,318
BUT I KNOW IT'S BEING RECORDED

1189
00:43:52,318 --> 00:43:55,188
AND I REALLY LOOK FORWARD TO

1190
00:43:55,188 --> 00:43:56,789
VIEWING THE RECORDING LATER OF

1191
00:43:56,789 --> 00:43:57,523
THE WEBCAST.

1192
00:43:57,523 --> 00:43:58,992
AGAIN, THANK YOU SO MUCH AND I

1193
00:43:58,992 --> 00:44:00,827
WISH YOU AN EXCELLENT REST OF

1194
00:44:00,827 --> 00:44:01,761
THE MEETING.

1195
00:44:01,761 --> 00:44:05,865
>> THANK YOU DR.
KLEINSTREUER,

1196
00:44:05,865 --> 00:44:09,102
APPRECIATE IT, SAFE TRAVELS.

1197
00:44:09,102 --> 00:44:15,875
>> SO LET US TURN TO

1198
00:44:15,875 --> 00:44:22,782
DR. CLAYTON'S DIRECTOR'S REPORT.

1199
00:44:22,782 --> 00:44:32,291
>> LET ME GRAB CONTROL
HERE.

1200
00:44:32,291 --> 00:44:34,494
WELL, THANK YOU SO MUCH EVERYONE

1201
00:44:34,494 --> 00:44:35,695
AND IT'S EXCITING TO BE WITH YOU

1202
00:44:35,695 --> 00:44:35,895
TODAY.

1203
00:44:35,895 --> 00:44:39,198
WE HAVE A LOT TO SHARE WITH YOU.

1204
00:44:39,198 --> 00:44:41,267
IT'S ALWAYS 1 OF MY FAVORITE

1205
00:44:41,267 --> 00:44:42,235
MEETINGS TO BE ABLE TO SHARE

1206
00:44:42,235 --> 00:44:43,736
WITH YOU ALL THE WORK THAT'S

1207
00:44:43,736 --> 00:44:46,739
BEEN GOING ON ACROSS NIH RELATED

1208
00:44:46,739 --> 00:44:49,842
TO WOMEN'S HEALTH AND SO, GIVING

1209
00:44:49,842 --> 00:44:51,744
THIS DIRECTOR'S REPORT IS 1 OF

1210
00:44:51,744 --> 00:44:54,180
THE WAYS THAT I LOVE TO DO THAT.

1211
00:44:54,180 --> 00:44:57,083
I WILL GIVE AN UPDATE ON ORWH

1212
00:44:57,083 --> 00:44:58,985
AND NIH IN TERMS OF LEADERSHIP,

1213
00:44:58,985 --> 00:45:01,187
I WILL PROVIDE SCIENTIFIC

1214
00:45:01,187 --> 00:45:02,588
UPDATES, SOME ORWH PROGRAM

1215
00:45:02,588 --> 00:45:07,427
UPDATES AND THEN, CLOSE OUT.

1216
00:45:07,427 --> 00:45:07,660
OKAY.

1217
00:45:07,660 --> 00:45:10,930
SO I'M GOING TO GO WITH THE

1218
00:45:10,930 --> 00:45:12,031
BOTTOM LINE UP FRONT HERE AND

1219
00:45:12,031 --> 00:45:13,766
GIVE YOU SOME DATA THAT I REALLY

1220
00:45:13,766 --> 00:45:17,704
WANT TO SHARE WITH YOU TODAY.

1221
00:45:17,704 --> 00:45:22,942
WE TOOK A LOOK AT ORWH'S CO

1222
00:45:22,942 --> 00:45:23,910
FUNDING FROM 1999-2024 TO SEE

1223
00:45:23,910 --> 00:45:25,978
THE IMPACT OF THAT CO FUNDING

1224
00:45:25,978 --> 00:45:26,879
WITH THE INSTITUTES AND CENTERS

1225
00:45:26,879 --> 00:45:30,717
AND IF YOU START AT THE BOTTOM,

1226
00:45:30,717 --> 00:45:35,588
CAN YOU SEE, FROM 1999 TO 2024,

1227
00:45:35,588 --> 00:45:38,157
WE HAVE SUPPORTED OVER 2000

1228
00:45:38,157 --> 00:45:40,593
UNIQUE GRANTS, SOME FUNDED FROM

1229
00:45:40,593 --> 00:45:44,564
MULTIPLE YEARS, THOSE HAVE LED

1230
00:45:44,564 --> 00:45:46,699
TO OVER 73,000 PUBLICATIONS THAT

1231
00:45:46,699 --> 00:45:51,704
SITE AT LEAST 1 ORWH CO FUNDED

1232
00:45:51,704 --> 00:45:52,271
GRANT.

1233
00:45:52,271 --> 00:45:54,841
NEXT LINE UP, AND THOSE HAVE LED

1234
00:45:54,841 --> 00:45:59,378
TO OVER 28,000 PATENT

1235
00:45:59,378 --> 00:46:00,847
APPLICATION SIGHTINGS, 7000, 612

1236
00:46:00,847 --> 00:46:01,214
PUBLICATIONS.

1237
00:46:01,214 --> 00:46:02,648
THE NEXT ROW UP AND AT THE VERY

1238
00:46:02,648 --> 00:46:09,088
TOP THERE, YOU CAN SEE 193 DRUG

1239
00:46:09,088 --> 00:46:11,090
LICENSES, CITING 406 PATENT

1240
00:46:11,090 --> 00:46:13,059
APPLICATIONS SUPPORTED BY ORWH

1241
00:46:13,059 --> 00:46:14,160
AND OTHER ICOs TO GIVE YOU A

1242
00:46:14,160 --> 00:46:16,362
SENSE OF WHAT THE IMPACT OF ORWH

1243
00:46:16,362 --> 00:46:18,464
HAS BEEN IN TERMS OF

1244
00:46:18,464 --> 00:46:19,465
COLLABORATING WITH OUR

1245
00:46:19,465 --> 00:46:21,000
INSTITUTES AND CENTERS AND

1246
00:46:21,000 --> 00:46:21,434
COLLEAGUES.

1247
00:46:21,434 --> 00:46:24,070
AND THE CONDITIONS THAT ARE

1248
00:46:24,070 --> 00:46:25,671
SUPPORTED BY THESE EFFORTS

1249
00:46:25,671 --> 00:46:27,306
EITHER GIVING NEW KNOWLEDGE OF

1250
00:46:27,306 --> 00:46:28,474
THE PUBLICATION OR IDENTIFYING

1251
00:46:28,474 --> 00:46:30,777
NEW TREATMENTS THROUGH DRUG

1252
00:46:30,777 --> 00:46:31,811
LICENSES, ARE HIGHLY RELEVANT TO

1253
00:46:31,811 --> 00:46:34,680
THE HELT OF WOMEN INCLUDING

1254
00:46:34,680 --> 00:46:37,717
DEMENTIA, HYPER LIP DEEMIA,

1255
00:46:37,717 --> 00:46:39,685
EPILEPSY, HYPER CLOOF THE ROL

1256
00:46:39,685 --> 00:46:41,721
AND OTHER CONDITIONS, SO BOTTOM

1257
00:46:41,721 --> 00:46:43,456
LINE UP FRONT HERE, WE'RE HERE

1258
00:46:43,456 --> 00:46:44,290
TO COLLABORATE WITH OUR

1259
00:46:44,290 --> 00:46:46,225
COLLEAGUES AND HAVE AN IMPACT TO

1260
00:46:46,225 --> 00:46:47,627
IMPROVE THE HEALTH OF WOMEN AND

1261
00:46:47,627 --> 00:46:51,164
THIS IS JUST 1 WAY WE DO THAT.

1262
00:46:51,164 --> 00:46:54,400
IN TERMS OF NIH AND ORWH UPDATES

1263
00:46:54,400 --> 00:46:56,969
I ALWAYS LIKE TO SHARE WITH YOU

1264
00:46:56,969 --> 00:46:58,271
THE LEADERSHIP UPDATES, I'M SURE

1265
00:46:58,271 --> 00:46:59,906
YOU ARE KEENLY AWARE THAT WE

1266
00:46:59,906 --> 00:47:00,973
HAVE WELCOMED RECENTLY THE

1267
00:47:00,973 --> 00:47:02,942
18th DIRECTOR OF THE NATIONAL

1268
00:47:02,942 --> 00:47:04,644
INSTITUTES OF HEALTH DR. JAY

1269
00:47:04,644 --> 00:47:06,712
BHATTACHARYA WE HAVE A NEW

1270
00:47:06,712 --> 00:47:09,849
PRINCIPAL DEPUTY DIRECTOR OF NIH

1271
00:47:09,849 --> 00:47:11,584
DR. MATTHEW MEMOLI, AND THEN YOU

1272
00:47:11,584 --> 00:47:16,355
HEARD FROM DR. NICOLE

1273
00:47:16,355 --> 00:47:18,457
KLEINSTREUER FOR DEPUTY DIRECTOR

1274
00:47:18,457 --> 00:47:20,059
FOR PROGRAM, COORDINATION,

1275
00:47:20,059 --> 00:47:20,760
PLANNING AND STRATEGIC

1276
00:47:20,760 --> 00:47:21,761
INITIATIVES AND I AM LOOKING

1277
00:47:21,761 --> 00:47:23,162
FORWARD TO EACH AND EVERY 1 OF

1278
00:47:23,162 --> 00:47:25,031
THEM AS WE MOVE FORWARD TO

1279
00:47:25,031 --> 00:47:26,065
ADVANCE WOMEN'S HEALTH RESEARCH.

1280
00:47:26,065 --> 00:47:28,267
WE'VE HAD A FEW CHANGES, YOU

1281
00:47:28,267 --> 00:47:30,803
MIGHT HAVE NOTICED, DR. OTA WANG

1282
00:47:30,803 --> 00:47:33,406
HAD A DIFFERENT SIGNATURE LINE

1283
00:47:33,406 --> 00:47:34,807
TODAY, DIFFERENT TITLE THERE

1284
00:47:34,807 --> 00:47:36,876
TODAY, WITH THE CHANGING

1285
00:47:36,876 --> 00:47:39,712
LEADERSHIP, THERE HAVE BEEN

1286
00:47:39,712 --> 00:47:42,181
SEVERAL OTHER CHANGES,

1287
00:47:42,181 --> 00:47:43,349
DR. CAROLYN HUTTER NAMED LAST

1288
00:47:43,349 --> 00:47:46,052
YEAR WAS ASKED TO SERVE AS THE

1289
00:47:46,052 --> 00:47:47,854
ACTING DIRECTOR OF THE NATIONAL

1290
00:47:47,854 --> 00:47:48,821
HUMAN GENOME RESEARCH INSTITUTE

1291
00:47:48,821 --> 00:47:51,924
AND LEFT THE OFFICE OF STRATEGIC

1292
00:47:51,924 --> 00:47:54,393
COORDINATION WITHOUT LEADERSHIP

1293
00:47:54,393 --> 00:47:56,462
DIRECTOR AND DR. OTA WANG WAS

1294
00:47:56,462 --> 00:47:57,997
TAPPED TO SERVE AS ACTING

1295
00:47:57,997 --> 00:47:59,799
DIRECTOR OF THE OFFICE OF

1296
00:47:59,799 --> 00:48:00,733
STRATEGIC COORDINATION WITH LEFT

1297
00:48:00,733 --> 00:48:04,270
US WITH AN OPEN DEPUTY DIRECTOR

1298
00:48:04,270 --> 00:48:07,106
POSITION AND CINDY CAUGHMAN WITH

1299
00:48:07,106 --> 00:48:10,309
THE OFFICE OF PORTFOLIO ANALYSIS

1300
00:48:10,309 --> 00:48:12,845
IS SERVING AS THE ACTING DEPUTY

1301
00:48:12,845 --> 00:48:14,046
DIRECTOR OF ORWH.  AND YOU WILL

1302
00:48:14,046 --> 00:48:15,014
SEE THESE NEW NAMES AND FACES

1303
00:48:15,014 --> 00:48:16,883
AND I WANT TO MAKE SURE YOU ARE

1304
00:48:16,883 --> 00:48:20,186
AWARE OF THE DOMINOES THAT

1305
00:48:20,186 --> 00:48:20,820
INITIATES THESE CHANGES.

1306
00:48:20,820 --> 00:48:22,288
I'M GOING TO PROVIDE YOU WITH A

1307
00:48:22,288 --> 00:48:26,392
COUPLE OF SCIENTIFIC UPDATES,

1308
00:48:26,392 --> 00:48:29,028
SINCE WE LAST MET FOR A FULL

1309
00:48:29,028 --> 00:48:30,630
MEETING, IT'S MY PLEASURE TO

1310
00:48:30,630 --> 00:48:33,332
SHARE WITH YOU, THIS PUBLICATION

1311
00:48:33,332 --> 00:48:37,136
THAT I LED ON BEHALF OF NIH

1312
00:48:37,136 --> 00:48:39,472
LEADERSHIP ENTITLED RECENT

1313
00:48:39,472 --> 00:48:40,306
DEVELOPMENTS OF WOMEN'S HEALTH

1314
00:48:40,306 --> 00:48:41,440
RESEARCH AT THE NATIONAL

1315
00:48:41,440 --> 00:48:42,541
INTUITYS OF HEALTH AND IT CAME

1316
00:48:42,541 --> 00:48:45,945
OUT LAST YEAR AND WE SUMMARIZED

1317
00:48:45,945 --> 00:48:48,547
ACROSS THE ENTIRE NIH, THE

1318
00:48:48,547 --> 00:48:49,815
WOMEN'S HEALTH RESEARCH EFFORTS

1319
00:48:49,815 --> 00:48:52,451
THAT THE INSTITUTES AND CENTERS

1320
00:48:52,451 --> 00:48:54,520
INDIVIDUALLY AND HOW WE MOVE

1321
00:48:54,520 --> 00:48:58,057
COLLECTIVELY TO HAVE A LARGER

1322
00:48:58,057 --> 00:48:59,792
IMPACT TO ADDRESS ALL THE

1323
00:48:59,792 --> 00:49:01,260
ASPECTS OF WOMEN'S HEALTH.

1324
00:49:01,260 --> 00:49:02,995
WE NOW KNOW OF COURSE WOMEN'S

1325
00:49:02,995 --> 00:49:06,198
HEALTH IS EVERYTHING THAT FITS A

1326
00:49:06,198 --> 00:49:09,402
WOMAN HEAD TO TOE INSIDE AND OUT

1327
00:49:09,402 --> 00:49:11,304
FAR BEYOND FEMALE REPRODUCTIVE

1328
00:49:11,304 --> 00:49:12,471
CONDITIONS AS IMPORTANT AS THEY

1329
00:49:12,471 --> 00:49:13,839
ARE, WE NEED TO ADDRESS THE

1330
00:49:13,839 --> 00:49:15,241
ENTIRE HEALTH OF WOMEN ACROSS

1331
00:49:15,241 --> 00:49:16,909
THE ENTIRE LIFE COURSE TO HAVE

1332
00:49:16,909 --> 00:49:17,576
THE MOST IMPACT.

1333
00:49:17,576 --> 00:49:19,145
WE NOW HAVE INSIGHTS ABOUT HOW

1334
00:49:19,145 --> 00:49:21,314
THE DISEASES AND CONDITIONS

1335
00:49:21,314 --> 00:49:23,716
AVENGHT WOMEN UNIQUELY,

1336
00:49:23,716 --> 00:49:24,083
DIFFERENTLY OR

1337
00:49:24,083 --> 00:49:25,318
DISPROPORTIONATELY AND WAYS TO

1338
00:49:25,318 --> 00:49:26,786
ACCELERATE TRANSLATION FROM THE

1339
00:49:26,786 --> 00:49:28,387
LABORATORY SCIENCE TO PRACTICAL

1340
00:49:28,387 --> 00:49:32,258
BENEFITS TO WOMEN AND THIS

1341
00:49:32,258 --> 00:49:34,093
PUBLICATION INCLUDES A TABLE AND

1342
00:49:34,093 --> 00:49:34,894
SUPPLEMENTARY MATERIAL OF

1343
00:49:34,894 --> 00:49:37,430
EXAMPLES OF EACH OF THE ICs

1344
00:49:37,430 --> 00:49:38,597
EFFORTS TO IMPROVE THE HEALTH OF

1345
00:49:38,597 --> 00:49:41,233
WOMEN AND IT WAS MY PLEASURE TO

1346
00:49:41,233 --> 00:49:51,510
CHAT ABOUT THIS WITH

1347
00:49:51,510 --> 00:49:52,144
DR. KIRSTEN BIBINS-DOMINGO CITED

1348
00:49:52,144 --> 00:49:52,378
THERE.

1349
00:49:52,378 --> 00:49:53,713
I ALSO WANT TO HIGHLIGHT A

1350
00:49:53,713 --> 00:49:55,681
RECENT REPORT FROM THE NATIONAL

1351
00:49:55,681 --> 00:50:00,619
CANCER INSTITUTE ON CANCER DEATH

1352
00:50:00,619 --> 00:50:00,987
RATES.

1353
00:50:00,987 --> 00:50:01,887
THERE WE GO.

1354
00:50:01,887 --> 00:50:04,423
THE 20 -- WHOOPS.

1355
00:50:04,423 --> 00:50:05,958
THIS IS MOVING QUICKER THAN I

1356
00:50:05,958 --> 00:50:07,893
NEED TODAY TO.

1357
00:50:07,893 --> 00:50:08,294
SORRY ABOUT THAT.

1358
00:50:08,294 --> 00:50:09,428
A 2025 REPORT LOOKEDDA THE DEATH

1359
00:50:09,428 --> 00:50:11,530
RATES AND SAW THE GOOD NEWS,

1360
00:50:11,530 --> 00:50:13,132
OVERALL DETH RATES FOR MEN,

1361
00:50:13,132 --> 00:50:14,867
WOMEN AND CHILDREN HAVE DECLINED

1362
00:50:14,867 --> 00:50:20,873
AND THAT IS FANTASTIC NEWS.

1363
00:50:20,873 --> 00:50:22,508
TWELVE OF 19 MOST COMMON CANCERS

1364
00:50:22,508 --> 00:50:25,044
IN WOMEN SHOWED DECREASES IN

1365
00:50:25,044 --> 00:50:25,311
MORTALITY.

1366
00:50:25,311 --> 00:50:28,381
FOURTEEN OF 20 MOST COMMON

1367
00:50:28,381 --> 00:50:30,082
CANCERS IN WOMEN SHOWED

1368
00:50:30,082 --> 00:50:31,384
DECREASES IN MORTALITY.

1369
00:50:31,384 --> 00:50:33,452
OWEVER THERE WAS AN INCREASE OF

1370
00:50:33,452 --> 00:50:35,321
CANCER IN WOMEN AT MULTIPLE

1371
00:50:35,321 --> 00:50:38,124
SITES EVERY YEAR FROM 2003

1372
00:50:38,124 --> 00:50:40,059
THROUGH 2021 WITH THE EXCEPTION

1373
00:50:40,059 --> 00:50:41,127
OF 2020.

1374
00:50:41,127 --> 00:50:43,129
SO WITH THAT INCREASE IN

1375
00:50:43,129 --> 00:50:46,132
INCIDENCE, DESPITE THE DECREASE

1376
00:50:46,132 --> 00:50:48,601
IN DEATH RATES WE STILL NEED TO

1377
00:50:48,601 --> 00:50:49,735
MAY ATTENTION TO SEX DIFFERENCES

1378
00:50:49,735 --> 00:50:51,237
AND MAKE SURE WE FIND A WAY TO

1379
00:50:51,237 --> 00:50:51,871
ADDRESS THAT.

1380
00:50:51,871 --> 00:50:55,808
RATES OF NEW CANCERS IN WOMEN

1381
00:50:55,808 --> 00:50:59,512
INCREASED IN THE BREAST, UTERUS,

1382
00:50:59,512 --> 00:51:02,214
COLON AND RECTUM, AND THEN IN

1383
00:51:02,214 --> 00:51:04,150
THE PAN KRE TINS KASP A R,

1384
00:51:04,150 --> 00:51:06,786
KIDNEY AND LIVER IN YOUNG ADULTS

1385
00:51:06,786 --> 00:51:08,020
AND AMONG WOMEN.

1386
00:51:08,020 --> 00:51:12,258
AND ALSO RISING RATES OF

1387
00:51:12,258 --> 00:51:15,394
ESTROGEN RECEPTOR-POSITIVE

1388
00:51:15,394 --> 00:51:19,465
BREAST CANCER AND FERTILITY

1389
00:51:19,465 --> 00:51:21,267
RATES, ADVANCING AGENT AT FIRST

1390
00:51:21,267 --> 00:51:23,803
BIRTH, RISE AND OBESITY AND

1391
00:51:23,803 --> 00:51:24,603
ALCOHOL COMSUMPTION AND NEW

1392
00:51:24,603 --> 00:51:30,409
CASES OF DEATHS FROM UTERINE

1393
00:51:30,409 --> 00:51:30,643
CANCER.

1394
00:51:30,643 --> 00:51:33,379
YOU CAN SEE IN THE GRAPH HERE OF

1395
00:51:33,379 --> 00:51:35,247
ANNUAL PERCENT CHANGE FROM

1396
00:51:35,247 --> 00:51:36,315
2018-2022, FOR MALES ON THE

1397
00:51:36,315 --> 00:51:38,651
LEFT, FEMALES ON THE RIGHT, THE

1398
00:51:38,651 --> 00:51:41,554
TICKER OTHERWISE BARS SHOW

1399
00:51:41,554 --> 00:51:43,189
REDUCTIONS IN DEATH RATE, THESE

1400
00:51:43,189 --> 00:51:44,790
ARE DEATH RATES SO THAT IS GREAT

1401
00:51:44,790 --> 00:51:46,092
NEWS TO SEE ALL OF THOSE

1402
00:51:46,092 --> 00:51:47,159
REDUCTIONS AND AT THE BOTTOM YOU

1403
00:51:47,159 --> 00:51:49,028
CAN SEE THAT LARGEST REDUCTION

1404
00:51:49,028 --> 00:51:50,362
IN BOTH MALES AND FEMALES IN

1405
00:51:50,362 --> 00:51:53,132
CANCER OF THE LUNG AND BRONCHUS,

1406
00:51:53,132 --> 00:51:54,767
NEXT UP FROM THE BOTTOM, FOR

1407
00:51:54,767 --> 00:51:57,336
WOMEN YOU CAN SEE OVARY IN

1408
00:51:57,336 --> 00:52:01,841
NONHODGKINS LYMPHOMA FOR MEN, SO

1409
00:52:01,841 --> 00:52:04,410
WE ARE PLEASED TO SEE THAT

1410
00:52:04,410 --> 00:52:06,946
STATISTIC REDUCTION FOR LONG AND

1411
00:52:06,946 --> 00:52:07,880
BRONCHUS CANCER IN WOMEN AND

1412
00:52:07,880 --> 00:52:08,047
MEN.

1413
00:52:08,047 --> 00:52:09,315
I WANT TO DRAW YOUR ATTENTION TO

1414
00:52:09,315 --> 00:52:12,852
THE TOP WHERE WE HAVE THE ORANGE

1415
00:52:12,852 --> 00:52:15,688
BARS INDICATING INCROSING DEATH

1416
00:52:15,688 --> 00:52:17,957
RATES, FOR NONMELANOMA SKIN

1417
00:52:17,957 --> 00:52:19,024
KAN--KANAER, BONES AND JOINTS

1418
00:52:19,024 --> 00:52:28,067
FOR MALES AND FOR FEMALES, AND

1419
00:52:28,067 --> 00:52:29,468
LIVER AND INTERHEPATIC

1420
00:52:29,468 --> 00:52:31,036
DEATHERATE FOR WOMEN.

1421
00:52:31,036 --> 00:52:32,404
SOPHISTICATEDY WE SEE TREND WEES

1422
00:52:32,404 --> 00:52:33,839
WANT TO PAY ATTENTION TO AS WE

1423
00:52:33,839 --> 00:52:37,543
LOOK AT THIS DATA ON A ROUTINE

1424
00:52:37,543 --> 00:52:39,845
BASIS. 

1425
00:52:39,845 --> 00:52:41,180
IT'S BEEN A GREAT EXPERIENCE

1426
00:52:41,180 --> 00:52:42,715
COLLABORATING WITH THE NATIONAL

1427
00:52:42,715 --> 00:52:46,252
CANCER INSTITUTE OVER THE YEARS

1428
00:52:46,252 --> 00:52:48,654
AND INVESTMENTS IN THAT

1429
00:52:48,654 --> 00:52:53,092
LONG-TERM COLLABORATION HAVE

1430
00:52:53,092 --> 00:52:55,294
REALLY PAID OFF IN THE AREA OF

1431
00:52:55,294 --> 00:53:03,302
VIROLOGY AND IN TERMS  TERMS OFG

1432
00:53:03,302 --> 00:53:05,070
TO IMMUNO DOSE INTERVENTIONS FOR

1433
00:53:05,070 --> 00:53:05,971
CERVICAL CANCER PREVENTION SO

1434
00:53:05,971 --> 00:53:07,640
WE'RE EXCITED TO SEE THAT MOST

1435
00:53:07,640 --> 00:53:09,875
RECENT DATA PUBLISHED AND THIS

1436
00:53:09,875 --> 00:53:11,143
ACCELERATES CERVICAL CANCER

1437
00:53:11,143 --> 00:53:13,512
PREVENTION BY MINIMIZING PATIENT

1438
00:53:13,512 --> 00:53:14,647
BURDEN WHILE MAINTAINING

1439
00:53:14,647 --> 00:53:15,147
EFFECTIVENESS OF THE

1440
00:53:15,147 --> 00:53:16,615
INTERVENTION CAN IT ADDRESSES

1441
00:53:16,615 --> 00:53:18,484
DIFFERENCES IN ACCESS TO

1442
00:53:18,484 --> 00:53:21,053
CERVICAL CANCER PREVENTION

1443
00:53:21,053 --> 00:53:21,987
RESOURCES, A STILL IMPORTANT

1444
00:53:21,987 --> 00:53:23,923
ISSUE ACROSS THE WORLD, NEXT. 

1445
00:53:23,923 --> 00:53:28,227
LET'S GO HERE.

1446
00:53:28,227 --> 00:53:30,429
I ALWAYS LIKE TO BRING YOU A

1447
00:53:30,429 --> 00:53:33,098
COUPLE EXAMPLES OF SEX AS A

1448
00:53:33,098 --> 00:53:33,832
BIOLOGICAL VARIABLE IN ACTION

1449
00:53:33,832 --> 00:53:35,768
AND OUR COLLEAGUES ACROSS THE

1450
00:53:35,768 --> 00:53:41,874
NIH HAVE DONE A FANTASTIC JOB IN

1451
00:53:41,874 --> 00:53:44,410
IMPLEMENTING AND APPLYING THAT

1452
00:53:44,410 --> 00:53:45,377
PERSPECTIVE.

1453
00:53:45,377 --> 00:53:50,015
HERE'S 1 FROM THE EEUNICE AND

1454
00:53:50,015 --> 00:53:53,152
THEY WERE LOOKING AT DNA

1455
00:53:53,152 --> 00:53:54,553
METHYLATION PATTERNS INDICATING

1456
00:53:54,553 --> 00:53:56,555
DIFFERENTIAL GENE EXPRESSION AND

1457
00:53:56,555 --> 00:53:58,557
THEY FOUND OVER 2400 PREVIOUSLY

1458
00:53:58,557 --> 00:54:00,326
UNREPORTED DNA SITES WITH

1459
00:54:00,326 --> 00:54:01,327
DIFFERENT METHYLATION PATTERNS.

1460
00:54:01,327 --> 00:54:03,629
THEY ALSO SHOWED THAT INCREASES

1461
00:54:03,629 --> 00:54:05,030
IN METHYLATION PATTERNS RESEARCH

1462
00:54:05,030 --> 00:54:07,600
ASSOCIATE WIDE GREATER NEONATAL

1463
00:54:07,600 --> 00:54:10,669
SIZE FROM MALE PLACENTAL SIZE

1464
00:54:10,669 --> 00:54:13,272
AND GREATER PLACENTAL SIZE FOR

1465
00:54:13,272 --> 00:54:16,008
FEMALE PLACENTAS AND THEY FOUND

1466
00:54:16,008 --> 00:54:18,944
SPECIFIC GENES THAT THEY KNEW

1467
00:54:18,944 --> 00:54:24,883
WERE LINKED TO PRETERM BIRTH,

1468
00:54:24,883 --> 00:54:26,452
PREELAMPSIA, AND HYPERTENSION IN

1469
00:54:26,452 --> 00:54:29,388
BOTH MALES AND FEMALE PLACENTA

1470
00:54:29,388 --> 00:54:30,889
INDICATING THAT MAY PLAY A ROLE

1471
00:54:30,889 --> 00:54:32,558
OF CHRONIC DISEASE LEALTER IN

1472
00:54:32,558 --> 00:54:34,860
LIFE FROM THESE PERSPECTIVES.

1473
00:54:34,860 --> 00:54:36,829
SO THESE EPIDEN GENETIC MODISHS

1474
00:54:36,829 --> 00:54:37,997
WE'RE SEEING PLAY A ROLE AND

1475
00:54:37,997 --> 00:54:39,498
WE'RE LOOKING AT SEX DIFFERENCES

1476
00:54:39,498 --> 00:54:42,034
THERE THROUGH THE NICHD FUNDED

1477
00:54:42,034 --> 00:54:42,334
RESEARCH.

1478
00:54:42,334 --> 00:54:44,703
HERE'S ANOTHER EXAMPLE FUNDED BY

1479
00:54:44,703 --> 00:54:47,806
SEVERAL OTHER INSTITUTES NINDS,

1480
00:54:47,806 --> 00:54:50,209
AND NIDDK IN THIS PLACE AND THEY

1481
00:54:50,209 --> 00:54:52,478
FOUND A NOVEL ROLE FOR

1482
00:54:52,478 --> 00:54:54,179
REGULATORY T-CELLS IN SEX

1483
00:54:54,179 --> 00:54:55,314
SPECIFIC PAIN PROGRESSION, WE DO

1484
00:54:55,314 --> 00:54:59,318
KNOW THERE ARE SEX DIFFERENCES

1485
00:54:59,318 --> 00:55:00,619
IN PAIN PROCESSING AND WOMEN

1486
00:55:00,619 --> 00:55:02,021
HAVE HIGHER RATES OF PAIN THAN

1487
00:55:02,021 --> 00:55:04,423
DO MEN, AND THIS STUDY LOOKED AT

1488
00:55:04,423 --> 00:55:07,393
WHETHER T-CELLS MIGHT PLAY A

1489
00:55:07,393 --> 00:55:09,261
ROLE IN PROCESSING, THEY WERE

1490
00:55:09,261 --> 00:55:10,863
LOOKING AT TREGULATORY T-CELLS

1491
00:55:10,863 --> 00:55:12,131
THAT ARE CONTROLLED BY GENE

1492
00:55:12,131 --> 00:55:13,966
LOCATED ON THE X-CHROMOSOME, OF

1493
00:55:13,966 --> 00:55:17,136
COURSE WE KNOW THAT T-CELLS PLAY

1494
00:55:17,136 --> 00:55:18,404
A ROLE IN IMMUNO MODULATION BUT

1495
00:55:18,404 --> 00:55:21,407
THIS IS A DISTINCT ROLE WHERE

1496
00:55:21,407 --> 00:55:23,575
T-REGULATORY CELLS WERE FOUND TO

1497
00:55:23,575 --> 00:55:25,511
INHIBIT NO SUSCEPTION IN A SEX

1498
00:55:25,511 --> 00:55:28,013
SPECIFIC WAY.

1499
00:55:28,013 --> 00:55:30,516
WHEN THEY DEPLETED MENINGIAL

1500
00:55:30,516 --> 00:55:31,784
T-REGULATORY CELLS IT INCREASED

1501
00:55:31,784 --> 00:55:33,185
SENSITIVITY TO A SPECIFIC TYPE

1502
00:55:33,185 --> 00:55:35,020
OF PAIN IN FEMALE MICE BUT NOT

1503
00:55:35,020 --> 00:55:38,157
MALE MICE AND THEY FOUND TWHA

1504
00:55:38,157 --> 00:55:41,360
SOME OF THESE TREG CELLS IN THE

1505
00:55:41,360 --> 00:55:44,296
MENING EASE PRODUCED ANNAL

1506
00:55:44,296 --> 00:55:48,534
GEEZIC COMPOUND WITH ENKEPH ALIN

1507
00:55:48,534 --> 00:55:50,836
AND FEMALE MICE HAD MORE THAN

1508
00:55:50,836 --> 00:55:52,371
MALE MICE.

1509
00:55:52,371 --> 00:55:53,872
THEY DID A VARIETY OF

1510
00:55:53,872 --> 00:55:55,074
INTERVENTIONS TO TEST THE RIGOR

1511
00:55:55,074 --> 00:55:58,210
OF THEIR FINDING AND THEY FOUND

1512
00:55:58,210 --> 00:55:59,578
OVERALL THAT T-REGULATORY CELLS

1513
00:55:59,578 --> 00:56:05,317
MAY BE KEY REGULATORS OF

1514
00:56:05,317 --> 00:56:06,819
SEX-SPECIFIC MECHANICAL PAIN

1515
00:56:06,819 --> 00:56:08,954
INFLAMMATION AND MAY EXPLAIN WHY

1516
00:56:08,954 --> 00:56:10,956
MEN AND WOMEN DIFFER IN THEIR

1517
00:56:10,956 --> 00:56:11,523
SENSITIVITY OF PAIN.

1518
00:56:11,523 --> 00:56:15,828
I WOULD LIKE TO END THIS LITTLE

1519
00:56:15,828 --> 00:56:18,430
SECTION BY HIGHLIGHTING THE

1520
00:56:18,430 --> 00:56:19,164
CONGRESSALLY MANDATED MEDICAL

1521
00:56:19,164 --> 00:56:21,333
RESEARCH PROGRAM WHO IS RELEASED

1522
00:56:21,333 --> 00:56:24,470
RESEARCH ON SEX AS A BIOLOGICAL

1523
00:56:24,470 --> 00:56:26,905
BARRIERS LAST YEAR WHICH EXTENDS

1524
00:56:26,905 --> 00:56:28,173
ACROSS CLINICAL RESEARCH TO

1525
00:56:28,173 --> 00:56:29,441
INCLUDE CLINICAL TRIALS WITH

1526
00:56:29,441 --> 00:56:30,175
REQUIREMENTS FOR CONSIDERATION

1527
00:56:30,175 --> 00:56:32,811
OF SEX AS A BEOLOGICAL VARIABLE

1528
00:56:32,811 --> 00:56:35,047
AND WE'RE REALLY EXCITED TO SEE

1529
00:56:35,047 --> 00:56:36,582
OUR PARTNERS IN D.O.D. MOVING

1530
00:56:36,582 --> 00:56:43,222
FORWARD IN THIS WAY.

1531
00:56:43,222 --> 00:56:47,326
IN TERMS AS SEX AS A VARIABLE,

1532
00:56:47,326 --> 00:56:48,627
THIS EXPLAINS HOW FUNDERS HAVE

1533
00:56:48,627 --> 00:56:50,429
MOVED FORWARD IN ADVANCING

1534
00:56:50,429 --> 00:56:53,132
REQUIREMENTS FOR SEX AS A

1535
00:56:53,132 --> 00:56:53,932
BEOLOGICAL VARIABLE AND

1536
00:56:53,932 --> 00:56:55,467
DISAGGREGATION OF DATA BY SEX.

1537
00:56:55,467 --> 00:57:00,072
AND YOU KNOW INCLUSION OF COURSE

1538
00:57:00,072 --> 00:57:01,173
IS NOT SYNONYMOUS WITH COUNTING

1539
00:57:01,173 --> 00:57:04,309
FOR SEX AS A BEOLOGICAL VARIABLE

1540
00:57:04,309 --> 00:57:05,911
AND WE'VE SEEN ACROSS NORTH

1541
00:57:05,911 --> 00:57:07,179
AMERICA FOR EXAMPLE, OVER THE

1542
00:57:07,179 --> 00:57:09,381
PAST FEW YEARS ALMOST A 3 TIMES

1543
00:57:09,381 --> 00:57:12,684
INCREASE IN THE PROPORTION OF

1544
00:57:12,684 --> 00:57:15,287
SEX STUDIES COMPARED TO SINGLE

1545
00:57:15,287 --> 00:57:18,624
SEX STUDIES AGAIN ACKNOWLEDGING

1546
00:57:18,624 --> 00:57:21,260
SEX CAN HAVE CHROMESOME HORMONE

1547
00:57:21,260 --> 00:57:23,162
AND MULTIPLE ORGAN LEVELS.

1548
00:57:23,162 --> 00:57:24,997
SO EXCITING TO SEE POLICIES

1549
00:57:24,997 --> 00:57:26,165
EXIST NOTHING MULTIPLE COUNTRIES

1550
00:57:26,165 --> 00:57:27,199
ACROSS THE WORLD AND INTERESTED

1551
00:57:27,199 --> 00:57:28,967
TO SEE WHAT THE UNITED KINGDOM

1552
00:57:28,967 --> 00:57:39,478
WILL COME UP WITH NEXT, COMING

1553
00:57:40,512 --> 00:57:40,646
SOON.

1554
00:57:40,646 --> 00:57:44,183
I'M ALSO EXCITED TO SHARE WITH

1555
00:57:44,183 --> 00:57:48,687
YOU A WORKSHOP IN GREECE BY THE

1556
00:57:48,687 --> 00:57:50,656
IRPT SECTION OF REGENERATIVE

1557
00:57:50,656 --> 00:57:51,824
MEDICINE IN MEN AND WOMEN'S

1558
00:57:51,824 --> 00:57:52,324
HEALTH.

1559
00:57:52,324 --> 00:57:55,327
YOU CAN SEE DR. OTA WANG CHAIRED

1560
00:57:55,327 --> 00:57:57,329
WITH ALONG WITH DR. KIMBERLY

1561
00:57:57,329 --> 00:57:58,530
POTTER AND OUR CONTRIBUTORS ARE

1562
00:57:58,530 --> 00:58:01,133
LISTED FOR THE REPORT.

1563
00:58:01,133 --> 00:58:03,001
REGENERATIVE MEDICINE IS A

1564
00:58:03,001 --> 00:58:04,269
PARTICULARLY EXCITING ASPECT OF

1565
00:58:04,269 --> 00:58:06,705
BIOMEDICINE IT HAS THE POTENTIAL

1566
00:58:06,705 --> 00:58:07,606
TO BRIDGE GAPS AND UNDERSTAND

1567
00:58:07,606 --> 00:58:08,841
THE ROLE OF SEX IN HEALTH AND

1568
00:58:08,841 --> 00:58:12,978
DEC AS YOU LOOK FORWARD TO

1569
00:58:12,978 --> 00:58:13,612
MODULATING REPAIRING, REBOOTING

1570
00:58:13,612 --> 00:58:15,314
THESE TISSUES TO A VARIETY OF

1571
00:58:15,314 --> 00:58:16,482
NEEDS AND TRANSLATING THAT

1572
00:58:16,482 --> 00:58:17,549
KNOWLEDGE INTO IMPROVED CARE FOR

1573
00:58:17,549 --> 00:58:19,384
WOMEN AND MEN AND A COUPLE OF

1574
00:58:19,384 --> 00:58:20,586
THE THEMES ARE LISTED HERE BUT

1575
00:58:20,586 --> 00:58:22,554
ON THE NEXT SLIDE, I'M GOING

1576
00:58:22,554 --> 00:58:26,558
SHOW YOU A COUPLE OF ADDITIONAL

1577
00:58:26,558 --> 00:58:28,193
PIECES OF INFORMATION FROM THAT

1578
00:58:28,193 --> 00:58:29,228
WORKSHOP, A COUPLE QUOTES HERE

1579
00:58:29,228 --> 00:58:31,129
ON THE RIGHT NOW THAT POLICIES,

1580
00:58:31,129 --> 00:58:32,498
AND PATIENTS WITH DISEASES SUCH

1581
00:58:32,498 --> 00:58:35,667
AS SICKLE CELL ARE LIVING LONGER

1582
00:58:35,667 --> 00:58:39,705
MORE RESEARCH IS NEEDED BEYOND

1583
00:58:39,705 --> 00:58:42,407
THAT FOR QUALITY OF LIFE AND

1584
00:58:42,407 --> 00:58:43,675
MATERNAL HEALTH, FROM 1 OF THE

1585
00:58:43,675 --> 00:58:46,311
ATTENDEES AS WELL AS INCREASED

1586
00:58:46,311 --> 00:58:53,852
RESEARCH ON THE FEMALE MILIEU

1587
00:58:53,852 --> 00:58:55,587
AND HORMONAL INFLUENZS AND SEX

1588
00:58:55,587 --> 00:58:56,955
INFLUENCES IN THE CARE AND

1589
00:58:56,955 --> 00:58:58,090
TREATMENT AND HOW THEY

1590
00:58:58,090 --> 00:59:00,292
EXPERIENCE HEALTH AND DISEASE,

1591
00:59:00,292 --> 00:59:01,827
SO MODEL SYSTEMS, NOVEL

1592
00:59:01,827 --> 00:59:05,931
ALTERNATIVE METHODS, THE NEED

1593
00:59:05,931 --> 00:59:06,398
FOR MULTIDISCIPLINARY

1594
00:59:06,398 --> 00:59:08,000
APPROACHES, THE OPPORTUNITY TO

1595
00:59:08,000 --> 00:59:08,634
BETTER UNDERSTAND, UNDERLYING

1596
00:59:08,634 --> 00:59:11,537
BIOLOGY AND THE IMPACT OF SEX

1597
00:59:11,537 --> 00:59:13,539
AND HORMONES AND THE NEED FOR

1598
00:59:13,539 --> 00:59:15,307
EMERGING THERAPIES TO TARGET

1599
00:59:15,307 --> 00:59:17,009
BEYOND THE SYMPTOMS OF ISOTOPE

1600
00:59:17,009 --> 00:59:20,078
ORDERS BUT THE CAUSES WERE

1601
00:59:20,078 --> 00:59:21,246
SEVERAL THEMES THAT WERE

1602
00:59:21,246 --> 00:59:21,813
HIGHLIGHTED.

1603
00:59:21,813 --> 00:59:23,549
TO GIVE YOU A LITTLE BIT OF AN

1604
00:59:23,549 --> 00:59:25,417
UPDATE ON SOME OF THE ORWH

1605
00:59:25,417 --> 00:59:27,019
PROGRAMS THAT OCCURRED SINCE WE

1606
00:59:27,019 --> 00:59:28,987
LAST MET IN FULL, IT'S ALWAYS

1607
00:59:28,987 --> 00:59:32,090
OUR PLEASURE TO ON BEHALF OF

1608
00:59:32,090 --> 00:59:42,634
NIH, LEAVE THE ANNUAL SYMPOSIUM,

1609
00:59:46,071 --> 00:59:48,307
IN ADDITION TO A REALLY ROBUST

1610
00:59:48,307 --> 00:59:49,374
AND AMAZING PANEL YOU CAN SEE

1611
00:59:49,374 --> 00:59:55,314
HERE WE ALSO HAD A CAP STONE

1612
00:59:55,314 --> 00:59:57,015
PRESENTATION, FROM DR. RAQUELL

1613
00:59:57,015 --> 00:59:58,850
HEALTH CHAIR OF INFORMATION

1614
00:59:58,850 --> 01:00:02,754
SCIENCES AND PROFESSOR SPELL MAN

1615
01:00:02,754 --> 01:00:04,323
AT THE COLLEGE, IT'S AVAILABLE

1616
01:00:04,323 --> 01:00:06,992
BY VIDEOCAST IF YOU MISS TODAY

1617
01:00:06,992 --> 01:00:12,064
EMPLOY --

1618
01:00:12,064 --> 01:00:12,431
MISSED IT.

1619
01:00:12,431 --> 01:00:15,968
I ALSO WANT TO UPDATE ON A

1620
01:00:15,968 --> 01:00:17,569
COLLABORATION WE'VE HAD WITH THE

1621
01:00:17,569 --> 01:00:18,437
INTRAMURAL PROGRAM.

1622
01:00:18,437 --> 01:00:20,372
THE BENCH TO BEDSIDE PROGRAM WAS

1623
01:00:20,372 --> 01:00:22,040
CREATED TO SEE NEW PART MERSHIPS

1624
01:00:22,040 --> 01:00:23,742
AMONG INSTITUTES AND CENTERS

1625
01:00:23,742 --> 01:00:24,776
BETWEEN BASIC SCIENCE AND

1626
01:00:24,776 --> 01:00:26,812
CLINICAL INVESTIGATORS AND THEN

1627
01:00:26,812 --> 01:00:28,780
IN 2006, THE PROGRAM WAS

1628
01:00:28,780 --> 01:00:31,750
EXPANDED TO INCLUDE EXTRAMURAL

1629
01:00:31,750 --> 01:00:34,286
COLLABORATIONS AND SINCE 2006,

1630
01:00:34,286 --> 01:00:37,489
ORWH HAS CO FUNDED 19 BENCH TO

1631
01:00:37,489 --> 01:00:38,957
BEDSIDE PROJECTS AT ALMOST

1632
01:00:38,957 --> 01:00:41,460
$5 MILLION AND WE'RE CO FUNDED

1633
01:00:41,460 --> 01:00:43,895
OF COURSE WITH THE DEPUTY

1634
01:00:43,895 --> 01:00:46,198
DIRECTOR FOR INTRAMURAL RESEARCH

1635
01:00:46,198 --> 01:00:47,099
AND OTHER ICOs.

1636
01:00:47,099 --> 01:00:49,267
SPECIFICALLY THIS PROGRAM ADDED

1637
01:00:49,267 --> 01:00:52,504
THE STRATEGIC PLAN, THE NIH-WIDE

1638
01:00:52,504 --> 01:00:55,540
STRATEGIC PLAN FOR RESEARCH ON

1639
01:00:55,540 --> 01:00:57,275
HEALTH ON WOMEN CALL TO

1640
01:00:57,275 --> 01:00:58,477
PROPOSALS WHEN WE BECAME

1641
01:00:58,477 --> 01:00:58,744
PARTNERS.

1642
01:00:58,744 --> 01:01:00,679
SO THIS IS 1 OF THE WAY WHAT'SY

1643
01:01:00,679 --> 01:01:02,180
ARE IMPROVING WOMEN'S HEALTH BY

1644
01:01:02,180 --> 01:01:03,115
COLLABORATING WITH THE

1645
01:01:03,115 --> 01:01:03,615
INTRAMURAL PROGRAM.

1646
01:01:03,615 --> 01:01:06,151
AN EXAMPLE OF 1 OF OUR RECENT

1647
01:01:06,151 --> 01:01:09,554
SUPPORTED PROGRAMS IS THE NOVEL

1648
01:01:09,554 --> 01:01:10,956
GUT MICROBIOME FACTORS AND

1649
01:01:10,956 --> 01:01:12,858
PREGNANCY AND EARLY CHILDHOOD OR

1650
01:01:12,858 --> 01:01:13,925
ETCHED STUDY.

1651
01:01:13,925 --> 01:01:16,628
AND THE INVESTIGATORS SUPPORTED

1652
01:01:16,628 --> 01:01:19,297
BY THAT RECENTLY FEATURED IN OUR

1653
01:01:19,297 --> 01:01:20,198
NIH REMETABOLISM'S HEALTH

1654
01:01:20,198 --> 01:01:22,234
RESEARCH SCIENTIFIC INTEREST

1655
01:01:22,234 --> 01:01:24,336
GROUP THAT WE CONVENE QUARTERLY,

1656
01:01:24,336 --> 01:01:26,638
AT LEAST QUARTERLY AROUND THE

1657
01:01:26,638 --> 01:01:31,476
NIH COMMUNITY TO PROVIDE UPDATES

1658
01:01:31,476 --> 01:01:36,915
AND DR. SINHA AND DR. HOURIGAN,

1659
01:01:36,915 --> 01:01:39,484
PRECEPTED ON THE LONG-TERM

1660
01:01:39,484 --> 01:01:44,289
METABOLIC HEALTH AND SHAPING THE

1661
01:01:44,289 --> 01:01:46,658
MICROBIOME IN SHAPING FUTURE

1662
01:01:46,658 --> 01:01:48,960
HEALTH RESPECTIVELY OUR OWN

1663
01:01:48,960 --> 01:01:50,495
DR. OTAWANG WAS THE MODERATOR

1664
01:01:50,495 --> 01:01:51,329
FOR THAT SESSION.

1665
01:01:51,329 --> 01:01:52,464
I AM ALSO PLEASED TO SHARE WITH

1666
01:01:52,464 --> 01:01:54,766
YOU THAT JUST RECENTLY WE WERE

1667
01:01:54,766 --> 01:01:58,203
PLEASED TO COLLABORATE WITH THE

1668
01:01:58,203 --> 01:01:59,471
UNIFORM SERVICES UNIVERSITY

1669
01:01:59,471 --> 01:02:00,372
MILITARY WOMEN'S ELGT RESEARCH

1670
01:02:00,372 --> 01:02:02,908
PROGRAM TO KICKOFF A NEW WEBINAR

1671
01:02:02,908 --> 01:02:07,913
SERIES, THE FIRST SESSION WAS ON

1672
01:02:07,913 --> 01:02:14,686
MENOPAUSE AND MIDLIFE HEGHT AND

1673
01:02:14,686 --> 01:02:19,157
DR. HADINE JOFFE AND HAD MIRANDA

1674
01:02:19,157 --> 01:02:22,461
JANVRIN AND THEY PRESENTED ON

1675
01:02:22,461 --> 01:02:23,595
MILITARY WOMEN ACCESSING

1676
01:02:23,595 --> 01:02:25,197
TREATMENT FOR MENOPAUSE SYMPTOMS

1677
01:02:25,197 --> 01:02:26,865
IN A PILOT STUDY RESPECTIVELY.

1678
01:02:26,865 --> 01:02:31,002
SO TUNE IN FOR FUTURE SESSIONS.

1679
01:02:31,002 --> 01:02:33,038
WE'VE BEEN VERY BUSY ACROSS THE

1680
01:02:33,038 --> 01:02:34,473
LAST YEAR COLLABORATING AND

1681
01:02:34,473 --> 01:02:36,308
DISSEMINATING OUR EFFORTS WITH

1682
01:02:36,308 --> 01:02:37,776
OUR PARTNERS AND I'VE BEEN SO

1683
01:02:37,776 --> 01:02:39,745
PLEASED TO BE INVITED TO PRESENT

1684
01:02:39,745 --> 01:02:42,948
AT MANY INSTITUTE AND CENTER

1685
01:02:42,948 --> 01:02:44,082
OFFICES, COUNCILS AND OTHER

1686
01:02:44,082 --> 01:02:45,684
SESSIONS AND JUST A FEW OF THEM

1687
01:02:45,684 --> 01:02:55,761
ARE LISTED HERE.

1688
01:02:55,761 --> 01:02:57,729
LAST YEAR THE NIH PAIN

1689
01:02:57,729 --> 01:03:02,667
CONSORTIUM WHICH IS AN NIH-WIDE

1690
01:03:02,667 --> 01:03:05,737
EFFORT TO STUDY PAIN, SO IN THE

1691
01:03:05,737 --> 01:03:08,173
2024 ANNUAL PAIN CONSORTIUM

1692
01:03:08,173 --> 01:03:10,142
MEETING, SEX DIFFERENCES IN

1693
01:03:10,142 --> 01:03:11,309
PAIN, DIFFERENT ACCESS TO PAIN

1694
01:03:11,309 --> 01:03:12,377
AND MANAGEMENT CARE AND PAIN

1695
01:03:12,377 --> 01:03:14,246
ACROSS THE LIFE SPAN WERE TOPICS

1696
01:03:14,246 --> 01:03:18,917
THAT WERE PRESENTED IN THAT MAY

1697
01:03:18,917 --> 01:03:19,851
2024 PRESENTATION CONSORTIUM

1698
01:03:19,851 --> 01:03:22,921
MEETING AND DR. OTA WANG

1699
01:03:22,921 --> 01:03:24,089
PROVIDED OPENING REMARKS AND

1700
01:03:24,089 --> 01:03:25,157
WE'RE THRILLED TO CONTINUE TO

1701
01:03:25,157 --> 01:03:26,091
SUPPORT THIS PAYING CONSORTIUM

1702
01:03:26,091 --> 01:03:27,726
AS IT MOVES FORWARD AND WE ARE

1703
01:03:27,726 --> 01:03:29,594
EXCITED THEY CHOSE TO FOCUS ON

1704
01:03:29,594 --> 01:03:37,135
SEX DIFFERENCES IN PAIN IN 2024.

1705
01:03:37,135 --> 01:03:38,303
AVAILABLE ON VIDEOCAST, YOU

1706
01:03:38,303 --> 01:03:42,641
HEARD FROM DR. KLEINSTREUER, ON

1707
01:03:42,641 --> 01:03:49,981
HER APPROACH TO NIAMS TO ADVANCE

1708
01:03:49,981 --> 01:03:51,183
SIGNIFICANT SCIENCES IN HEALTH.

1709
01:03:51,183 --> 01:03:53,685
THERE ARE MANY.

1710
01:03:53,685 --> 01:03:55,253
THE MOLECULAR TRANSDUCERS OF

1711
01:03:55,253 --> 01:03:56,888
PHYSICAL ACTIVITY SON SORTIUM,

1712
01:03:56,888 --> 01:04:01,159
10 YEAR PROGRAM, LARGEST

1713
01:04:01,159 --> 01:04:03,028
TARGETED NIH INVESTMENT WITH THE

1714
01:04:03,028 --> 01:04:04,462
MECHANISMS WITH HOW PHYSICAL

1715
01:04:04,462 --> 01:04:06,198
ACTIVITY IMPROVES HEALTH AND

1716
01:04:06,198 --> 01:04:07,899
PREVENTS DISEASE, IT'S

1717
01:04:07,899 --> 01:04:08,967
CATALOGING BIOLOGICAL MOLL QUEUE

1718
01:04:08,967 --> 01:04:10,802
KIEWLS THAT ARE AFFECTED BY

1719
01:04:10,802 --> 01:04:12,470
EXERCISE IN PEOPLE, LOOKING AT

1720
01:04:12,470 --> 01:04:15,006
HOW THEY ALTERED BY AGE, SEX,

1721
01:04:15,006 --> 01:04:16,274
BODY COMPOSITION, FITNESS LEVEL

1722
01:04:16,274 --> 01:04:17,576
AND EXPOSURE TO EXERCISE AND

1723
01:04:17,576 --> 01:04:19,945
THIS HAS THE POETIC TEBTIAL TO

1724
01:04:19,945 --> 01:04:25,250
HELP US UNDERSTAND WAT  -- AT A

1725
01:04:25,250 --> 01:04:27,118
MOLECULAR LEVEL, INFLUENZS OF

1726
01:04:27,118 --> 01:04:28,153
PHYSICAL ACTIVITY THESE ARE

1727
01:04:28,153 --> 01:04:30,856
IMPORTANT STUDIES AND THEY'VE

1728
01:04:30,856 --> 01:04:33,058
ALREADY SHOWN EXDIFFERENCES IN

1729
01:04:33,058 --> 01:04:34,159
THE PUBLISHED INFORMATION.

1730
01:04:34,159 --> 01:04:42,567
IN TERMS OF FEMALE SCIENTIFIC

1731
01:04:42,567 --> 01:04:46,204
CONDITIONS, NCATS AND SUPPORTING

1732
01:04:46,204 --> 01:04:47,973
DRUG DEVELOPMENT TOOLS FOR

1733
01:04:47,973 --> 01:04:49,674
PREGNANCY AND WOMEN'S HEALTH.

1734
01:04:49,674 --> 01:04:51,042
WE KNOW PREGINANCE

1735
01:04:51,042 --> 01:04:51,743
SEPARTICULARLY CHALLENGING TO

1736
01:04:51,743 --> 01:04:54,179
STUDY AND THIS IS 1 WAY TO MOVE

1737
01:04:54,179 --> 01:04:56,147
FORWARD WITH NIAMS TO DO STUDIES

1738
01:04:56,147 --> 01:04:58,250
WE COULD BT DO OTHER WISE SO

1739
01:04:58,250 --> 01:04:59,985
WE'RE LOOKING FORWARD TO THEIR

1740
01:04:59,985 --> 01:05:00,685
RESULTS.

1741
01:05:00,685 --> 01:05:02,287
THE NATIONAL INSTITUTE OF MENTAL

1742
01:05:02,287 --> 01:05:04,923
HEALTH HAS LAUNCHED A NOTICE

1743
01:05:04,923 --> 01:05:07,292
LOOKING FOR APPLICATIONS AROUND

1744
01:05:07,292 --> 01:05:07,926
EXPLAINABLE ARTIFICIAL

1745
01:05:07,926 --> 01:05:08,660
INTELLIGENCE RESEARCH INCLUDING

1746
01:05:08,660 --> 01:05:11,630
FOR THE DESIGN AND TESTING OF

1747
01:05:11,630 --> 01:05:13,265
COMPUTATIONAL MODELS TO IMITATE

1748
01:05:13,265 --> 01:05:16,268
SEX DIFFERENCES IN CLINICAL

1749
01:05:16,268 --> 01:05:16,568
PHENOTYPES.

1750
01:05:16,568 --> 01:05:18,403
IT'S A PARTICULARLY IMPORTANT

1751
01:05:18,403 --> 01:05:22,307
APPROACH AS WE MOVE TO MORE

1752
01:05:22,307 --> 01:05:23,141
COMPUTATIONAL APPROACHES, IT'S

1753
01:05:23,141 --> 01:05:25,143
IM  PERRATIVE WE ACCOUNT FOR SEX

1754
01:05:25,143 --> 01:05:27,512
AS A BIOLOGICAL VARIABLE AT THE

1755
01:05:27,512 --> 01:05:29,614
OUT SET AS WE MOVE FORWARD.

1756
01:05:29,614 --> 01:05:31,483
AND THEN NIDCR CLEARED A CONCEPT

1757
01:05:31,483 --> 01:05:35,954
AT THEIR COUNCIL RECENTLY

1758
01:05:35,954 --> 01:05:38,757
LOOKING AT OPTICAL IMAGES

1759
01:05:38,757 --> 01:05:39,991
MIEGZAL DENTAL ORAL,

1760
01:05:39,991 --> 01:05:40,725
CRANIOFACIAL MEDICINE, WE ARE

1761
01:05:40,725 --> 01:05:42,460
THRILLED TO SEE THE WORK AND

1762
01:05:42,460 --> 01:05:44,429
LOOK FORWARD TO COLLABORATING

1763
01:05:44,429 --> 01:05:47,065
WITH OUR COLLEAGUES ON THESE

1764
01:05:47,065 --> 01:05:47,299
EFFORTS.

1765
01:05:47,299 --> 01:05:51,169
THESE ARE JUST A FEW OF THE

1766
01:05:51,169 --> 01:05:52,604
MAMs EFFORTS UNDERWAY TO HELP

1767
01:05:52,604 --> 01:05:53,605
WOMEN'S HEALTH.

1768
01:05:53,605 --> 01:05:55,674
WE CONTINUED TO ADVANCE AND

1769
01:05:55,674 --> 01:05:56,641
HEALTH WOMEN'S HEALTH THROUGH

1770
01:05:56,641 --> 01:05:57,609
STRAY JECTORY TEENLIC

1771
01:05:57,609 --> 01:05:58,410
PARTNERSHIPS.

1772
01:05:58,410 --> 01:06:01,980
I WILL HAWAII  HIGH -- HIGHLIGHW

1773
01:06:01,980 --> 01:06:02,514
MUCH THOSE HERE.

1774
01:06:02,514 --> 01:06:06,184
WE WILL SEE AND HERE FROM

1775
01:06:06,184 --> 01:06:09,254
DR. DINA P A LTOO, LATER IN THE

1776
01:06:09,254 --> 01:06:09,955
PROGRAM, CENTRALIZED FUNDING

1777
01:06:09,955 --> 01:06:10,789
OPPORTUNITIES ARE AVAILABLE AT

1778
01:06:10,789 --> 01:06:12,590
THAT WEBSITE.

1779
01:06:12,590 --> 01:06:13,858
THE NATIONAL HEALTH INTERVIEW

1780
01:06:13,858 --> 01:06:16,661
SURVEY LED BY CDC REACHING OVER

1781
01:06:16,661 --> 01:06:17,595
35,000 HOUSEHOLDS, WE

1782
01:06:17,595 --> 01:06:20,999
COLLABORATED TO ADD QUESTIONS OF

1783
01:06:20,999 --> 01:06:22,133
MENOPAUSE TO THAT EFFORT FOR

1784
01:06:22,133 --> 01:06:22,834
THIS YEAR.

1785
01:06:22,834 --> 01:06:26,805
WE HEARD FROM DR. K ABOUT THE

1786
01:06:26,805 --> 01:06:27,639
MENOPAUSE PREVENTION PROGRAM, A

1787
01:06:27,639 --> 01:06:29,341
CRITICAL EFFORT FOR MULTIPLE

1788
01:06:29,341 --> 01:06:31,576
AGENCIES INVOLVED IN LOOKING AT

1789
01:06:31,576 --> 01:06:34,546
MIDLIFE HEALTH AND MENOPAUSE

1790
01:06:34,546 --> 01:06:36,481
SYMPTOMS AND HOPEFULLY

1791
01:06:36,481 --> 01:06:37,949
PRIORITIZATION OF FUTURE

1792
01:06:37,949 --> 01:06:39,985
RESEARCH BASED ON SCIENTIFIC

1793
01:06:39,985 --> 01:06:41,086
DISCOURSE IN THIS VERY IMPORTANT

1794
01:06:41,086 --> 01:06:41,419
SPACE.

1795
01:06:41,419 --> 01:06:43,254
WE ARE COLLABORATING WITH THE

1796
01:06:43,254 --> 01:06:45,123
OFFICE OF EXTRAMURAL SEED, SEED

1797
01:06:45,123 --> 01:06:46,791
OFFICE AND OUR IC COLLEAGUESAs

1798
01:06:46,791 --> 01:06:50,028
WELL AS CDC AND FDA ON THE SMALL

1799
01:06:50,028 --> 01:06:51,262
BUSINESS INNOVATION TRANSFER,

1800
01:06:51,262 --> 01:06:53,865
FUNDING OPPORTUNITY WHICH IS A

1801
01:06:53,865 --> 01:06:55,600
MULTIAGENCY EFFORT IN WOMEN'S

1802
01:06:55,600 --> 01:06:59,671
HELT RESEARCH HAS NOW BEEN

1803
01:06:59,671 --> 01:07:00,939
 ADDED

1804
01:07:00,939 --> 01:07:05,810
FOR THE FIEVERLT  -- FIRST TIME.

1805
01:07:05,810 --> 01:07:09,180
WE ARE ADDING THAT IN 2025, HELP

1806
01:07:09,180 --> 01:07:11,149
US GET WORD OUT ABOUT THIS

1807
01:07:11,149 --> 01:07:12,083
AMAZING OPPORTUNITY IN THE

1808
01:07:12,083 --> 01:07:13,818
RESEARCH SPACE AND WE CONTINUE

1809
01:07:13,818 --> 01:07:17,922
TO COLLABORATE ACROSS NIH AS NIH

1810
01:07:17,922 --> 01:07:19,691
MOVES FORWARD INICISM ELEMENTING

1811
01:07:19,691 --> 01:07:25,497
THE SIMPLIFIED REVIEW FRAMEWORK

1812
01:07:25,497 --> 01:07:28,233
OR SRF, SABV IS SUPPORTING THAT

1813
01:07:28,233 --> 01:07:33,004
RELATED TO RIGOR AND

1814
01:07:33,004 --> 01:07:34,072
REPRODUCIBILITY AND CONTINUES TO

1815
01:07:34,072 --> 01:07:40,545
SCORE THE APPLICATIONS AND

1816
01:07:40,545 --> 01:07:42,480
INCLUDED PROMINENTLY TO TRAIN

1817
01:07:42,480 --> 01:07:45,350
AND UPDATE THE SABV RUVIEWERS

1818
01:07:45,350 --> 01:07:46,184
AND FRAMEWORK.

1819
01:07:46,184 --> 01:07:47,819
SO EXCITED TO CONTINUE OUR

1820
01:07:47,819 --> 01:07:49,821
COLLABORATION WITH CSR IN THAT

1821
01:07:49,821 --> 01:07:50,822
REGARD AND OER.

1822
01:07:50,822 --> 01:07:52,824
IN ADDITION TO OFFICE

1823
01:07:52,824 --> 01:07:54,859
INFRASTRUCTURE PROGRAMS WE

1824
01:07:54,859 --> 01:07:58,663
INITIATED A COLLABORATION WITH

1825
01:07:58,663 --> 01:08:01,066
THEM TO OTHER SHARED INSTRUMENTS

1826
01:08:01,066 --> 01:08:01,633
PROGRAM.

1827
01:08:01,633 --> 01:08:04,402
THIS PROGRAM IS PIVOTAL IN

1828
01:08:04,402 --> 01:08:05,136
ENABLING CLINICAL TRANSLATIONAL

1829
01:08:05,136 --> 01:08:06,071
RESEARCH INCLUDING IN WOMEN'S

1830
01:08:06,071 --> 01:08:08,440
HELT AND AS WOMEN'S HEALTH AS

1831
01:08:08,440 --> 01:08:10,675
NOW BEEN EXPLICITLY ADDED TO THE

1832
01:08:10,675 --> 01:08:11,342
FUNDING OPPORTUNITY THEY WENT

1833
01:08:11,342 --> 01:08:12,911
BACK AND TOOK A LOOK AT THE

1834
01:08:12,911 --> 01:08:14,646
PUBLICATIONS AND WERE ABLE TO

1835
01:08:14,646 --> 01:08:16,181
DEMONSTRATE OVER A THOUSAND

1836
01:08:16,181 --> 01:08:18,249
PUBLICATIONS REEL KEEPSAKES VABT

1837
01:08:18,249 --> 01:08:23,521
TO WOMEN'S HEALTH FROM

1838
01:08:23,521 --> 01:08:23,788
FY22-FY24.

1839
01:08:23,788 --> 01:08:26,458
A VARIETY OF INSTRUMENTS RANGING

1840
01:08:26,458 --> 01:08:29,661
FROM IMAGING TO SALES ORDERS AND

1841
01:08:29,661 --> 01:08:30,261
OTHERS IMPLEMENTATION ARE

1842
01:08:30,261 --> 01:08:32,363
SUPPORTED THROUGH THIS PROGRAM.

1843
01:08:32,363 --> 01:08:34,532
IT SUPPORTS MULTIPLE INSTITUTE

1844
01:08:34,532 --> 01:08:36,367
AND CENTER GRANTEES ON MULTIPLE

1845
01:08:36,367 --> 01:08:38,870
POPPICS WHO USE INSTRUMENTS SO

1846
01:08:38,870 --> 01:08:41,372
THIS IS 1 OF THE WAYS WE CAN

1847
01:08:41,372 --> 01:08:43,041
LEVERAGE ON AND CAPITALIZE ON

1848
01:08:43,041 --> 01:08:49,147
INVESTMENT FROM OUR

1849
01:08:49,147 --> 01:08:52,750
ICO PARTNERS, TOPICS INCLUDING

1850
01:08:52,750 --> 01:08:56,488
BREAST CANCER, UTERINE CANCER

1851
01:08:56,488 --> 01:08:58,056
AND HETEROZYGOTTIC OUTWOMANS AND

1852
01:08:58,056 --> 01:09:00,358
I CAN'T WAIT TO SEE WHAT THIS

1853
01:09:00,358 --> 01:09:01,292
SUPPORTS NEXT.

1854
01:09:01,292 --> 01:09:08,166
YOU HEARD FROM DR. KLEINSTREUER,

1855
01:09:08,166 --> 01:09:09,501
HOW IMPORTANT IT IS TO ADDRESS

1856
01:09:09,501 --> 01:09:10,902
THE CHRONIC DISEASES WE'RE

1857
01:09:10,902 --> 01:09:12,504
SEEING IN OUR COUNTRY.

1858
01:09:12,504 --> 01:09:14,239
AND SHE HIGHLIGHTED HOW THOSE

1859
01:09:14,239 --> 01:09:15,073
RATES DIFFERENT FROM OTHER

1860
01:09:15,073 --> 01:09:17,275
COUNTRIES AND YOU MAY RECALL

1861
01:09:17,275 --> 01:09:18,877
SEFORT MEMBERS OF THE ADVISORY

1862
01:09:18,877 --> 01:09:23,014
COMMITTEE WERE PART OF

1863
01:09:23,014 --> 01:09:23,982
ACWRSEVERAL YEARS AGO WHEN NIH

1864
01:09:23,982 --> 01:09:25,483
CALLED ON CONGRESS TO ELECTRIC

1865
01:09:25,483 --> 01:09:27,452
AT OUR INVESTMENTS ACROSS

1866
01:09:27,452 --> 01:09:29,454
INVESTMENTS IN CHRONIC

1867
01:09:29,454 --> 01:09:31,556
DEBILITATING CONDITIONS,

1868
01:09:31,556 --> 01:09:32,724
SURVIVAL RATES AND MATERNAL

1869
01:09:32,724 --> 01:09:34,192
MORTALITY AND AS WE LOOK AT

1870
01:09:34,192 --> 01:09:35,393
CHRONIC CONDITIONS WE SUPPORTED

1871
01:09:35,393 --> 01:09:37,362
A NATIONAL ACOOED MES REPORT ON

1872
01:09:37,362 --> 01:09:38,963
ADVANCING RESEARCH AND CHRONIC

1873
01:09:38,963 --> 01:09:40,365
CONDITIONS IN WOMEN, THAT

1874
01:09:40,365 --> 01:09:43,101
DEVELOPED, THAT LED TO A REPORT

1875
01:09:43,101 --> 01:09:45,303
THAT HIGHLIGHTED A FRAMEWORK

1876
01:09:45,303 --> 01:09:46,971
THATY WE COULD USE GOING FORWARD

1877
01:09:46,971 --> 01:09:49,174
TO ADDRESS BIOLOGICAL AND

1878
01:09:49,174 --> 01:09:50,808
SOCIETAL FACTORS THAT INFLUENCE

1879
01:09:50,808 --> 01:09:51,776
DISEASE PREVALENCE, DIAGNOSIS

1880
01:09:51,776 --> 01:09:53,244
AND MANAGEMENT, FOR WOMEN AND

1881
01:09:53,244 --> 01:09:55,613
PROVIDE A PULTY DIMENSIONAL

1882
01:09:55,613 --> 01:09:57,182
RESEARCH DRIVEN STRATEGY TO

1883
01:09:57,182 --> 01:09:58,449
UNDERSTANDING CHRONIC DISEASES

1884
01:09:58,449 --> 01:09:59,083
IN WOMEN.

1885
01:09:59,083 --> 01:10:01,386
WE BUILT UPON THAT AND ISSUED

1886
01:10:01,386 --> 01:10:03,121
FUNDING OPPORTUNITIES FOR AN

1887
01:10:03,121 --> 01:10:07,559
RO-1 AND R21 WITH 7 ICO PARTNERS

1888
01:10:07,559 --> 01:10:09,894
AND FY23, AND 24, AND I'M

1889
01:10:09,894 --> 01:10:11,563
HIGHLIGHTING THE 24 DATA HERE

1890
01:10:11,563 --> 01:10:13,698
WITH OUR 7 ICO PARTNERS, WE'RE

1891
01:10:13,698 --> 01:10:17,035
ABLE TO FUND 21 AWARDS, 9 RO-1S

1892
01:10:17,035 --> 01:10:20,572
AND 12 R21S AND YOU CAN SEE THE

1893
01:10:20,572 --> 01:10:22,674
FUNDING HERE ON THE RIGHT IN THE

1894
01:10:22,674 --> 01:10:25,343
GRAPH IN MILLIONS, SO HERE ARE

1895
01:10:25,343 --> 01:10:28,513
THE TOTAL AMOUNTS TOTAL

1896
01:10:28,513 --> 01:10:30,348
$8.4 MILLION IN FY24, NEARLY

1897
01:10:30,348 --> 01:10:30,515
8.4.

1898
01:10:30,515 --> 01:10:31,983
AND A LITTLE BIT MORE

1899
01:10:31,983 --> 01:10:33,384
INFORMATION HERE, IN TERPS OF

1900
01:10:33,384 --> 01:10:35,887
THE SPECIFIC CONDITIONS THAT ARE

1901
01:10:35,887 --> 01:10:38,289
BEING ADDRESSED IN THIS REALLY

1902
01:10:38,289 --> 01:10:43,394
UNIQUE PROGRAM, FIRST OF ITS

1903
01:10:43,394 --> 01:10:45,530
KIND, LOOKING AT ISSUES THAT

1904
01:10:45,530 --> 01:10:52,303
AFFECT WOMEN AND MEN SUCH AS

1905
01:10:52,303 --> 01:10:56,241
AORTIC STENOSIS, CARDIOVASCULAR

1906
01:10:56,241 --> 01:11:01,713
DISEASE, PREVENTION, HIV

1907
01:11:01,713 --> 01:11:03,982
INFECTION, SYSTEMIC LUPUS

1908
01:11:03,982 --> 01:11:05,250
ARROWTHEMAITOSEIS SO LIGHTING ON

1909
01:11:05,250 --> 01:11:13,157
THE LEFT THE INVESTIGATORS AND

1910
01:11:13,157 --> 01:11:16,861
ON THE ON THE X-KROMSOME, WE

1911
01:11:16,861 --> 01:11:18,263
KNOW OBESITY IS REALLY IMPORTANT

1912
01:11:18,263 --> 01:11:21,599
IN A FACTOR OF THE CHRONIC

1913
01:11:21,599 --> 01:11:24,102
DECEASED DEVELOPMENT, TARGETING

1914
01:11:24,102 --> 01:11:25,937
ESTROGEN SENSITIVE NEURONS

1915
01:11:25,937 --> 01:11:27,672
VERSUS FRAILTY IN FEMALES,

1916
01:11:27,672 --> 01:11:32,443
FRAILTY IS A CRITICAL ISSUE IN

1917
01:11:32,443 --> 01:11:34,612
OLDER AND OBSTRUCTIVE PULMONARY

1918
01:11:34,612 --> 01:11:37,081
FEMALES, ALONG WITH NHLBI, WE

1919
01:11:37,081 --> 01:11:39,417
SEE RISING COPD RATES AND HIGHER

1920
01:11:39,417 --> 01:11:40,785
MORTALITY RATES IN WOMEN AS

1921
01:11:40,785 --> 01:11:42,120
COMPARED TO MEN SO WE WANT TO BE

1922
01:11:42,120 --> 01:11:45,923
ABLE TO UNDERSTAND THOSE

1923
01:11:45,923 --> 01:11:47,225
CONDITION BETTER SO IT'S BEEN AN

1924
01:11:47,225 --> 01:11:50,928
OPPORTUNITY TO ADDRESS GAPS IN

1925
01:11:50,928 --> 01:11:51,963
UNDERSTUDIED CHRONIC DISEASES IN

1926
01:11:51,963 --> 01:11:54,032
WOMEN THROUGH THIS FUNDING

1927
01:11:54,032 --> 01:11:55,199
OPPORTUNITY WITH INTUITYS AND

1928
01:11:55,199 --> 01:11:55,433
CENTERS.

1929
01:11:55,433 --> 01:11:56,534
IN ADDITION I WANT TO SHOW

1930
01:11:56,534 --> 01:12:01,673
NUCLEOTIDES TERMS OF MEMBERS OF

1931
01:12:01,673 --> 01:12:03,441
APPLICATIONS TD BREAK DOWN OF

1932
01:12:03,441 --> 01:12:05,043
NIH EN--STRATEGIESITUTES AND

1933
01:12:05,043 --> 01:12:07,445
CENTERS WITH NICHD LEADING WELL,

1934
01:12:07,445 --> 01:12:09,981
AND THE DARKER GREEN BARS

1935
01:12:09,981 --> 01:12:11,015
INDICATE THOSE APPLICATIONS

1936
01:12:11,015 --> 01:12:12,550
FUNDED THAT ARE IN FEMALE

1937
01:12:12,550 --> 01:12:13,518
SPECIFIC CONDITIONS AND YOU CAN

1938
01:12:13,518 --> 01:12:15,520
SEE THAT RELATED TO THE TOTAL.

1939
01:12:15,520 --> 01:12:17,555
AGAIN, REALLY EXCITED TO BE ABLE

1940
01:12:17,555 --> 01:12:23,695
TO MOVE THIS RESEARCH FORWARD.

1941
01:12:23,695 --> 01:12:25,229
ALSO MY PLEASURE TO SHARE WITH

1942
01:12:25,229 --> 01:12:28,399
YOU A RECENT UPDATE ON THE SCORE

1943
01:12:28,399 --> 01:12:29,701
PROGRAM WAS PRESENTED AT THE

1944
01:12:29,701 --> 01:12:31,736
ORGANIZATION FOR THE STUDY OF

1945
01:12:31,736 --> 01:12:36,207
SEX DIFFERENCES ANNUAL MEETING

1946
01:12:36,207 --> 01:12:38,643
AND DR. CHAIRED AND MODERATED A

1947
01:12:38,643 --> 01:12:40,445
SESSION WITH 3 SCORE

1948
01:12:40,445 --> 01:12:41,713
INVESTIGATORS PRESENTING  ON

1949
01:12:41,713 --> 01:12:45,216
ALCOHOL USE, ON THE BRAIN GUT

1950
01:12:45,216 --> 01:12:52,590
MICROBIOME INTERACTIONS AND

1951
01:12:52,590 --> 01:12:53,091
OTHER TOPICS.

1952
01:12:53,091 --> 01:12:54,492
THE SCORE PROGRAM IS MOVING

1953
01:12:54,492 --> 01:12:57,995
FORWARD AND IT'S OUR PLEASURE TO

1954
01:12:57,995 --> 01:12:59,731
WORK WITH OSSD ON THEIR EFFORTS.

1955
01:12:59,731 --> 01:13:01,933
YOU HEARD FROM DR. HIGGINS

1956
01:13:01,933 --> 01:13:03,501
EARLIER ON RURAL HEGHT AND I

1957
01:13:03,501 --> 01:13:05,169
WANT TO HIGHLIGHT AND TELL OUR

1958
01:13:05,169 --> 01:13:06,571
ADVISORY MEMBERS THAT WE HAVE

1959
01:13:06,571 --> 01:13:08,339
BEEN WORKING OVER 5 YEARS IN A

1960
01:13:08,339 --> 01:13:09,273
COLLABORATION BUILDING WITH THE

1961
01:13:09,273 --> 01:13:09,974
NATIONAL EN--STRATEGIESITUTE OF

1962
01:13:09,974 --> 01:13:12,410
GENERAL UPON SCIENCES THAT LEAD

1963
01:13:12,410 --> 01:13:13,678
CONGRESSALLY MANDATED IDEA

1964
01:13:13,678 --> 01:13:14,712
STATES OR INSTITUTIONAL

1965
01:13:14,712 --> 01:13:15,880
DEVELOPMENT ARK WARD STATES.

1966
01:13:15,880 --> 01:13:16,714
IDEA STATES ARE THOSE STATES IN

1967
01:13:16,714 --> 01:13:19,817
THE U.S. THAT RECEIVE

1968
01:13:19,817 --> 01:13:20,518
HISTORICALLY LOWER NIH GRANT

1969
01:13:20,518 --> 01:13:22,487
FUNDING AND YOU CAN SEE THEM

1970
01:13:22,487 --> 01:13:24,889
INDICATED HERE ON THE RIGHT.

1971
01:13:24,889 --> 01:13:28,459
AND OVER THE YEARS, WE INIT I

1972
01:13:28,459 --> 01:13:29,694
SHALY STARTED LEVERAGING WITH

1973
01:13:29,694 --> 01:13:32,463
THE IDEA STATES PROGRAM WITH

1974
01:13:32,463 --> 01:13:33,164
ADMINISTRATIVE SUPPLEMENTS,

1975
01:13:33,164 --> 01:13:34,298
OPPORTUNITIES FOR INVESTIGATORS

1976
01:13:34,298 --> 01:13:36,801
FUNDED BY IDEA TO ADDRESS

1977
01:13:36,801 --> 01:13:38,636
WOMEN'S HEALTH AND FROM THE LAST

1978
01:13:38,636 --> 01:13:43,141
4 YEARS WE'VE NOW FUNDED 83

1979
01:13:43,141 --> 01:13:44,175
ADMINISTRATIVE SUPPLEMENTS,

1980
01:13:44,175 --> 01:13:44,675
ALMOST $23.4 MILLION OF

1981
01:13:44,675 --> 01:13:47,078
INVESTMENTS OF OOH RWH, NIGMS

1982
01:13:47,078 --> 01:13:51,315
AND OTHER  INSTITUTES AND CENTES

1983
01:13:51,315 --> 01:13:54,085
IN AREA SO THIS IS AN NIH-WIDE

1984
01:13:54,085 --> 01:13:55,153
PROGRAM NOW.

1985
01:13:55,153 --> 01:13:58,189
TO DATE TWEEF FUND THE 21 OF THE

1986
01:13:58,189 --> 01:14:00,558
23, PLUS PUERTO RICO AND LAST WE

1987
01:14:00,558 --> 01:14:02,994
WE EXPANDED THE PROGRAM TO

1988
01:14:02,994 --> 01:14:07,131
INCLUDE CENTERS OF BIOMEDICAL

1989
01:14:07,131 --> 01:14:09,767
RESEARCH OR COBREs IN WOMEN'S

1990
01:14:09,767 --> 01:14:10,168
HEALTH.

1991
01:14:10,168 --> 01:14:12,203
WE ALSO KNOW NEW TRICIAN IS

1992
01:14:12,203 --> 01:14:12,937
PARTICULARLY IMPORTANT ISSUE FOR

1993
01:14:12,937 --> 01:14:14,772
THE HEALTH OF WOMEN AND THERE

1994
01:14:14,772 --> 01:14:15,773
ARE GEOGRAPHIC DIFFERENCES IN

1995
01:14:15,773 --> 01:14:19,110
MUSEUM TRICIAN AND IT'S

1996
01:14:19,110 --> 01:14:19,544
NUTRITION DEFICIENCY

1997
01:14:19,544 --> 01:14:19,877
CONSEQUENCES.

1998
01:14:19,877 --> 01:14:21,412
AT THE UNIVERSITY OF KANSAS

1999
01:14:21,412 --> 01:14:22,713
LEVERAGING BIG DATA TO IMPROVE

2000
01:14:22,713 --> 01:14:23,948
WOMEN'S HEALTH AND I MENTIONED 1

2001
01:14:23,948 --> 01:14:26,150
OF THE PROGRAMS THERE IS ON

2002
01:14:26,150 --> 01:14:27,885
TELEMEDICINE BUT ALSO IN

2003
01:14:27,885 --> 01:14:28,619
REFERAGEING BIG DATA IN A

2004
01:14:28,619 --> 01:14:31,255
VARIETY OF OTHER WAYS, SEX BASED

2005
01:14:31,255 --> 01:14:33,191
PRECISION MEDICINE AT TULANE IN

2006
01:14:33,191 --> 01:14:37,862
LOUISIANA IS OUR THIRD C OBRE

2007
01:14:37,862 --> 01:14:39,330
AND STAY TUNED FOR NEXT TIME WE

2008
01:14:39,330 --> 01:14:40,298
WERE TOGETHER.

2009
01:14:40,298 --> 01:14:45,069
LAST YEAR WE WERE ABLE TO HAVE

2010
01:14:45,069 --> 01:14:46,904
THE FIRST SYMPOSIUM OF THESE

2011
01:14:46,904 --> 01:14:48,306
RESEARCHERS TO TALK ABOUT THEIR

2012
01:14:48,306 --> 01:14:48,539
EFFORTS.

2013
01:14:48,539 --> 01:14:50,541
SO I HOPE YOU CAN SEE THAT

2014
01:14:50,541 --> 01:14:51,609
WORKING COLLABORATIVELY WITH

2015
01:14:51,609 --> 01:14:53,578
NIIMRKS MS AND BUILDING ON

2016
01:14:53,578 --> 01:14:54,512
MULTIIDEA STATES PROGRAMS THAT

2017
01:14:54,512 --> 01:14:56,080
THEY HAVE INVESTED IN AND THE

2018
01:14:56,080 --> 01:14:57,615
ICs INVESTED IN, WE HAVE

2019
01:14:57,615 --> 01:14:59,784
WORKED TO EXPAND WOMEN'S HEALTH

2020
01:14:59,784 --> 01:15:01,986
AND REACH AND EXPANDED THE REACH

2021
01:15:01,986 --> 01:15:03,454
ACROSS COUNTRY INTO THESE STATES

2022
01:15:03,454 --> 01:15:08,493
TO ADDRESS THE NEEDS ACROSS THE

2023
01:15:08,493 --> 01:15:08,826
NATION.

2024
01:15:08,826 --> 01:15:13,998
I MENTIONED THIS COLLABORATION

2025
01:15:13,998 --> 01:15:18,402
WITH THE SBIR/STTR PROGRAM OFTEN

2026
01:15:18,402 --> 01:15:19,570
CALLED AMERICA'S SEED FUND X.

2027
01:15:19,570 --> 01:15:21,005
THIS PROGRAM IS FOR SMALL

2028
01:15:21,005 --> 01:15:21,672
BUSINESS INFOIVATION.

2029
01:15:21,672 --> 01:15:23,407
WOMEN'S HEALTH HAS BEEN ADDED

2030
01:15:23,407 --> 01:15:24,909
AND WE'VE HOSTED SEVERAL

2031
01:15:24,909 --> 01:15:26,644
WEBINARS WHERE AT EACH OF THESE

2032
01:15:26,644 --> 01:15:27,578
WEBINARS THE SEED OFFICE PRESENT

2033
01:15:27,578 --> 01:15:28,746
OFFICE OF DIVERSITY THIS

2034
01:15:28,746 --> 01:15:29,146
OPPORTUNITY.

2035
01:15:29,146 --> 01:15:30,381
WE HIGHLIGHTED A FEW ITEMS BUT

2036
01:15:30,381 --> 01:15:32,717
EACH OF THOSE INSTITUTES AND

2037
01:15:32,717 --> 01:15:33,985
CENTERS HIGHLIGHTED WOMEN'S

2038
01:15:33,985 --> 01:15:35,720
HEALTH RELEVANT ADVANCES THAT

2039
01:15:35,720 --> 01:15:39,056
HAVE BEEN FUNDED THROUGH THE

2040
01:15:39,056 --> 01:15:41,526
SBIR/STTR PROGRAM, MAKING CLEAR

2041
01:15:41,526 --> 01:15:51,469
THE OPPORTUNITY FOR THIS

2042
01:15:51,469 --> 01:15:52,737
NONDILUTIVE MANDATORY ISSUING

2043
01:15:52,737 --> 01:15:53,804
THAT HAS BEEN HANDED.

2044
01:15:53,804 --> 01:15:56,173
THE NEXT 1 IS JUNE 25th.

2045
01:15:56,173 --> 01:16:02,046
SO PLEASE JOIN US TO HEAR ABOUT

2046
01:16:02,046 --> 01:16:03,648
OPPORTUNITIES FOR SBIR/STTR

2047
01:16:03,648 --> 01:16:05,983
FUNDING AND HELP US GET THE WORD

2048
01:16:05,983 --> 01:16:09,053
OUT ABOUT THIS AMAZING PROGRAM.

2049
01:16:09,053 --> 01:16:10,187
I'M ALSO PARTICULARLY DELIGHTED

2050
01:16:10,187 --> 01:16:12,757
TO SHARE WITH YOU THE OFFICE OF

2051
01:16:12,757 --> 01:16:14,725
AUTOIMMUNE DISEASE RESEARCH AND

2052
01:16:14,725 --> 01:16:16,127
WITHIN THE RWHAS REPORTED THEIR

2053
01:16:16,127 --> 01:16:18,563
FIRST REPORT OF ACHIEVEMENT FOR

2054
01:16:18,563 --> 01:16:21,999
FISCAL YEAR 23 AND 24, THAT

2055
01:16:21,999 --> 01:16:23,634
REPORT IS AVAILABLE ONLINE AND

2056
01:16:23,634 --> 01:16:25,937
THAT HIGHLIGHTS THE PROGRESS

2057
01:16:25,937 --> 01:16:28,839
THAT'S' BEEN MADE TOWARD THE

2058
01:16:28,839 --> 01:16:29,540
CONGRESSIONAL DIRECTIVES SET

2059
01:16:29,540 --> 01:16:31,175
FORTH, WITHIN THE ESTABLISHMENT

2060
01:16:31,175 --> 01:16:33,377
AND WE ARE EXCITED TO SHARE THAT

2061
01:16:33,377 --> 01:16:33,911
NEWS WITH YOU.

2062
01:16:33,911 --> 01:16:41,352
PLEAS CHECK THAT OUT.

2063
01:16:41,352 --> 01:16:50,161
WE ALSO SUPPORTED THE NATIONAL

2064
01:16:50,161 --> 01:16:51,128
ACADEMIES OF SYSTEMIC WORK

2065
01:16:51,128 --> 01:16:56,200
ISSUES BECAUSE WE KNOW A HEALTHY

2066
01:16:56,200 --> 01:16:56,901
ECOSYSTEM INCLUDES HEALTHY

2067
01:16:56,901 --> 01:16:58,769
WORKPLACES AND THAT INCLUDES

2068
01:16:58,769 --> 01:16:59,904
PHYSICAL AND MENTAL HEALTH.

2069
01:16:59,904 --> 01:17:00,538
PLEASE CHECK OUT RETINAL

2070
01:17:00,538 --> 01:17:01,105
LOCATION PORT THERE.

2071
01:17:01,105 --> 01:17:02,840
AND I WILL HIGHLIGHT 2 OF OUR

2072
01:17:02,840 --> 01:17:04,475
TRAVEL AWARDS.

2073
01:17:04,475 --> 01:17:06,911
OUR OSSD ANNUAL ME MEETING

2074
01:17:06,911 --> 01:17:09,914
TRAVEL AWARDS DR. AMANDA QUARS

2075
01:17:09,914 --> 01:17:11,916
ON SEX DIFFERENCES IN CLINICAL

2076
01:17:11,916 --> 01:17:14,518
TRIAL ENROLLMENT IN U.S.

2077
01:17:14,518 --> 01:17:16,621
PSYCHIATRIC DISORDERS AND A

2078
01:17:16,621 --> 01:17:20,224
THIRD YEAR MEDICAL STUDENT NEFIA

2079
01:17:20,224 --> 01:17:24,462
CHACKO, IS LOOKING AT VASCULAR

2080
01:17:24,462 --> 01:17:27,898
DYSFUNCTION IN ASSOCIATED WITH

2081
01:17:27,898 --> 01:17:31,068
POST MENOPAUSAL MICE, AND THENAD

2082
01:17:31,068 --> 01:17:34,305
LYNN ALEXANDER LOOKING AT APOE 4

2083
01:17:34,305 --> 01:17:36,240
GENOTYPES AND MEMORY DECLINE IN

2084
01:17:36,240 --> 01:17:38,275
MENOPAUSE AND ALSO LOOKING AT

2085
01:17:38,275 --> 01:17:41,612
MENOPAUSE CARE IN A NOVEL

2086
01:17:41,612 --> 01:17:43,280
FACILITATED GROUP CARE MODEL.

2087
01:17:43,280 --> 01:17:44,915
SO CONGRATULATIONS TO ALL OF OUR

2088
01:17:44,915 --> 01:17:46,751
TRAVEL AWARDEES AND I WILL WRAP

2089
01:17:46,751 --> 01:17:48,719
UP WITH DAT A SHARE WITH YOU

2090
01:17:48,719 --> 01:17:50,287
ONCE A YEAR, HERE IS THE BUDGET

2091
01:17:50,287 --> 01:17:55,159
HISTORY OF OUR FOUNDING IN 1991,

2092
01:17:55,159 --> 01:17:56,794
OUR FOUND NOTHING 1990 AND YOU

2093
01:17:56,794 --> 01:17:58,963
CAN SEE IN 2002 A BIG BUMP UP

2094
01:17:58,963 --> 01:18:03,901
FOR THE FORMATION OF THE BIRCH

2095
01:18:03,901 --> 01:18:07,038
PROGRAM, PLATBUDGET UNTIL ABOUT

2096
01:18:07,038 --> 01:18:08,439
2021, INCREING IN 2023, WITH THE

2097
01:18:08,439 --> 01:18:09,940
FORMATION OF THE OFFICE OF

2098
01:18:09,940 --> 01:18:13,511
AUTOIMMUNE DEC WERE AND OUR 2024

2099
01:18:13,511 --> 01:18:14,712
NUMBERS, 77.76 MILLION.

2100
01:18:14,712 --> 01:18:16,647
IN TERMS OF HOW THAT BREAKS OUT

2101
01:18:16,647 --> 01:18:18,482
IN TERMS OF OUR PARTICULAR

2102
01:18:18,482 --> 01:18:21,619
SIGNATURE PROGRAMS, THAT DATA IS

2103
01:18:21,619 --> 01:18:22,987
PRESENTED HERE, WE CO FUND WITH

2104
01:18:22,987 --> 01:18:26,791
VIRTUALLY ALL THE INSTITUTES AND

2105
01:18:26,791 --> 01:18:27,958
CENTERS ENUMERATED HERE AND A

2106
01:18:27,958 --> 01:18:28,926
VARIETY OF PROGRAMS HERE ON THE

2107
01:18:28,926 --> 01:18:31,429
LEFT HERE, SO WE ARE WORKING

2108
01:18:31,429 --> 01:18:33,631
HARD TO COLLABORATE WITH ALL THE

2109
01:18:33,631 --> 01:18:34,799
INSTITUTES AND CENTERS ACROSS

2110
01:18:34,799 --> 01:18:36,867
ALL OUR PROGRAM IN A WAY THAT IS

2111
01:18:36,867 --> 01:18:38,269
VALUE ADDED TO THE INSTITUTES

2112
01:18:38,269 --> 01:18:41,205
AND CENTERS THAT ADDRESS GAPS IN

2113
01:18:41,205 --> 01:18:42,273
THE NIH PORTFOLIO AND

2114
01:18:42,273 --> 01:18:44,408
OPPORTUNITIES FOR TOPICS THAT

2115
01:18:44,408 --> 01:18:45,576
OVERLAP MULTIPLE INSTITUTES AND

2116
01:18:45,576 --> 01:18:47,411
CENTERS SO THAT WE'RE

2117
01:18:47,411 --> 01:18:49,180
COMPLIMENTARY TO THE IC EFFORTS

2118
01:18:49,180 --> 01:18:51,716
IN ADVANCING WOMEN'S HEALTH.

2119
01:18:51,716 --> 01:18:53,751
WRAPPING THIS UP, WE ARE SMALL

2120
01:18:53,751 --> 01:18:55,052
OFFICE, BUT I CAN ARGUE THAT WE

2121
01:18:55,052 --> 01:18:57,254
HAVE HAD A BIG IMPACT, I

2122
01:18:57,254 --> 01:18:58,756
HIGHLIGHTED FOR YOU AT THE

2123
01:18:58,756 --> 01:18:59,957
BEGINNING OUR IMPACT IN CO

2124
01:18:59,957 --> 01:19:02,860
FUNDING RESEARCH IN TERMS OF

2125
01:19:02,860 --> 01:19:04,495
DRUG LICENSES, WHICH IS ONLY 1

2126
01:19:04,495 --> 01:19:10,835
WAY TO MEASURE I  -- IMPACT.

2127
01:19:10,835 --> 01:19:12,002
THERAPEUTIC INTERVENTIONS,

2128
01:19:12,002 --> 01:19:12,603
COMPARATIVE STUDIES CLINICAL

2129
01:19:12,603 --> 01:19:14,438
TRIALS ARE ALL OTHER WAY WE HAVE

2130
01:19:14,438 --> 01:19:15,339
SUPPORTED AND IMPACTED THE

2131
01:19:15,339 --> 01:19:17,875
HEALTH OF WOMEN, IT'S BEEN OUR

2132
01:19:17,875 --> 01:19:18,909
PLEASURE TO COLLABORATE WITH

2133
01:19:18,909 --> 01:19:20,745
MULTIPLE INSTITUTES AND CENTERS

2134
01:19:20,745 --> 01:19:25,449
THROUGH THE YEARS, AND WE TOOK A

2135
01:19:25,449 --> 01:19:27,017
LOOK AT 2013-2024 AND SAW WE

2136
01:19:27,017 --> 01:19:29,120
SUPPORTED OVER 2000 PROJECTS,

2137
01:19:29,120 --> 01:19:32,022
MOST FREQUENTLY CO INVESTING

2138
01:19:32,022 --> 01:19:38,262
WITH NICHD, NHLBI, NIAMS, NIAD,

2139
01:19:38,262 --> 01:19:40,097
AND NIDDK, AS WE INNERTEND TO

2140
01:19:40,097 --> 01:19:41,632
MAKE EVERY DOLLAR WORK AS HARD

2141
01:19:41,632 --> 01:19:42,533
AS POSSIBLE TO IMPROVE THE

2142
01:19:42,533 --> 01:19:45,736
HEALTH OF WOMEN AND CONTINUE TO

2143
01:19:45,736 --> 01:19:46,470
WORK COLLABORATIVELY WITH OUR

2144
01:19:46,470 --> 01:19:49,006
COLLEAGUES TO BE ABLE TO

2145
01:19:49,006 --> 01:19:51,008
LEVERAGE AND MAKE SURE OUR

2146
01:19:51,008 --> 01:19:54,245
INVESTMENTSA THE NIRE H ARE

2147
01:19:54,245 --> 01:19:55,346
STRATEGIC AND EFFECTIVE.

2148
01:19:55,346 --> 01:19:56,614
IT'S ALSO MY DISTINCT PLEASURE

2149
01:19:56,614 --> 01:19:58,716
TO ASK YOU TO SAVE THE DATE FOR

2150
01:19:58,716 --> 01:20:01,485
THE LAUNCH OF THE NIH-WIDE

2151
01:20:01,485 --> 01:20:02,286
STRATEGIC PLAN FOR AUTOIMMUNE

2152
01:20:02,286 --> 01:20:03,554
DISEASE WERE AND THAT IS GOING

2153
01:20:03,554 --> 01:20:07,525
TO BE ON JULY 21st AT 1 P.M. 

2154
01:20:07,525 --> 01:20:08,659
INFORMATION IS AVAILABLE HERE SO

2155
01:20:08,659 --> 01:20:10,661
MEAS DO JOIN US FOR THAT --

2156
01:20:10,661 --> 01:20:12,963
PLEASE DO JOIN US FOR THAT

2157
01:20:12,963 --> 01:20:13,898
EXCITING EVENT.

2158
01:20:13,898 --> 01:20:15,533
OTHER EVENTS UPCOMING, I

2159
01:20:15,533 --> 01:20:18,369
MENTIONED THE SBIR WEBINAR IN

2160
01:20:18,369 --> 01:20:18,569
JUNE.

2161
01:20:18,569 --> 01:20:20,805
IN JULY WE'RE HAVING A WOMEN'S

2162
01:20:20,805 --> 01:20:24,241
HEALTH RESEARCH ROUND TABLEOT

2163
01:20:24,241 --> 01:20:26,277
VAGINAL MICROBIOME AND

2164
01:20:26,277 --> 01:20:27,878
IMPLICATIONS ARE WOMEN'S HEALTH.

2165
01:20:27,878 --> 01:20:30,214
OUR NEXT MEETING IS ON

2166
01:20:30,214 --> 01:20:32,016
OCTOBER 7th, IN-PERSON MEETING

2167
01:20:32,016 --> 01:20:33,083
WITH A 35th ANNIVERSARY

2168
01:20:33,083 --> 01:20:34,919
SESSION, OUR PROGRAM MEETING OUR

2169
01:20:34,919 --> 01:20:42,293
ANNUAL SCORE AND BIRCWH AND THEN

2170
01:20:42,293 --> 01:20:44,261
OUR P2 P MENOPAUSE WORKSHOP,

2171
01:20:44,261 --> 01:20:46,297
PLEASE MARK YOUR CALENDARS FOR

2172
01:20:46,297 --> 01:20:48,632
THOSE EXCITING OPPORTUNITIES AND

2173
01:20:48,632 --> 01:20:48,899
EVENTS.

2174
01:20:48,899 --> 01:20:51,936
IT IS OUR PRIVILEGE TO BE

2175
01:20:51,936 --> 01:20:53,504
CELEBRATING 35 YEARS OF WOMEN'S

2176
01:20:53,504 --> 01:20:55,206
HEALTH RESEARCH AT NIH ADVANCING

2177
01:20:55,206 --> 01:20:57,308
THE HEALTH OF WOMEN THROUGH

2178
01:20:57,308 --> 01:20:58,242
RESEARCH AND INNOVATION, SO

2179
01:20:58,242 --> 01:21:00,311
THROUGH THIS YEAR, WE WILL BE

2180
01:21:00,311 --> 01:21:01,712
HAVING SEVERAL EVENTS, EPISODES

2181
01:21:01,712 --> 01:21:03,147
AND YOU KNOW NOTIFICATIONS, SO

2182
01:21:03,147 --> 01:21:05,249
STAY TUNED IF ARE THAT ON OUR

2183
01:21:05,249 --> 01:21:08,586
WEBSITE, AND OF COURSE, JOIN US

2184
01:21:08,586 --> 01:21:10,487
ON OCTOBER 7th.

2185
01:21:10,487 --> 01:21:12,289
AND WITH THAT, I WANT TO THANK

2186
01:21:12,289 --> 01:21:13,457
YOU FOR YOUR ATTENTION.

2187
01:21:13,457 --> 01:21:17,061
I WENT A BIT OVER, MY APOLOGIES

2188
01:21:17,061 --> 01:21:18,229
DR. OTA WANG, THERE WAS SO MUCH

2189
01:21:18,229 --> 01:21:19,496
I WANTED TO SHOW WITH OUR

2190
01:21:19,496 --> 01:21:20,931
MEMBERS AND SO WHAT WE CAN DO TO

2191
01:21:20,931 --> 01:21:25,302
GET BACK ON TIME IF YOU LIKE, WE

2192
01:21:25,302 --> 01:21:26,837
CAN DO ANY URGENT QUESTIONS NOW

2193
01:21:26,837 --> 01:21:28,772
BUT WE CAN SAVE THEM FOR OPEN

2194
01:21:28,772 --> 01:21:30,774
DISCUSSION IF THAT WORKS BETTER

2195
01:21:30,774 --> 01:21:31,876
FOR OUR SCHEDULE.

2196
01:21:31,876 --> 01:21:33,711
I THINK WE'RE ACTUALLY OKAY.

2197
01:21:33,711 --> 01:21:35,813
AND YOU COULD PROBABLY TAKE A

2198
01:21:35,813 --> 01:21:36,614
QUESTION OR 2.

2199
01:21:36,614 --> 01:21:36,881
>> OKAY.

2200
01:21:36,881 --> 01:21:41,952
>> BEFORE WE MOVE ON TO
DR. P A

2201
01:21:41,952 --> 01:21:43,287
LTOO'S PRESENTATION.

2202
01:21:43,287 --> 01:21:43,687
>> GREAT, OKAY.

2203
01:21:43,687 --> 01:21:47,324
>> WE ARE OKAY WITH OUR
TIMING.

2204
01:21:47,324 --> 01:21:48,592
SO ADVISORY COMMITTEE MEMBERS

2205
01:21:48,592 --> 01:21:50,661
ANY QUESTIONS OR COMMENTS ABOUT

2206
01:21:50,661 --> 01:21:52,029
ANY OF THE UPDATES OR OTHER

2207
01:21:52,029 --> 01:21:53,230
TOPICS AND WE STILL ALSO HAVE

2208
01:21:53,230 --> 01:22:03,741
TIME LATER IN THE DAY FOR OPEN

2209
01:22:12,149 --> 01:22:12,549
DISCUSSION.

2210
01:22:12,549 --> 01:22:13,918
>> QUIET GROUP TODAY.

2211
01:22:13,918 --> 01:22:15,319
>> I THINK THEY'RE STILL

2212
01:22:15,319 --> 01:22:17,321
DIGESTING ALL THE INFORMATION

2213
01:22:17,321 --> 01:22:17,955
YOU'VE GIVEN THEM.

2214
01:22:17,955 --> 01:22:19,890
IT WAS QUITE SPECTACULAR, I

2215
01:22:19,890 --> 01:22:21,425
THINK WHAT A TESTAMENT TO THE

2216
01:22:21,425 --> 01:22:25,629
OFFICE AND THE STAFF HERE.

2217
01:22:25,629 --> 01:22:28,098
>> YOU KNOW DR. OTA WANG,
I AM

2218
01:22:28,098 --> 01:22:29,633
SO EXCITED EVERY TIME WE HAVE

2219
01:22:29,633 --> 01:22:31,936
THIS MEETING TO SHARE THE AA

2220
01:22:31,936 --> 01:22:34,238
MAZING WORK THAT THE TEAM AT

2221
01:22:34,238 --> 01:22:36,006
ORWH HAVE DONE AND YOU'RE

2222
01:22:36,006 --> 01:22:37,308
ABSOLUTELY RIGHT AND FOLKS WORK

2223
01:22:37,308 --> 01:22:38,609
VERY, VERY HARD AND I WANT TO

2224
01:22:38,609 --> 01:22:40,911
ACKNOWLEDGE ALL THE FORMER ORWH

2225
01:22:40,911 --> 01:22:46,016
STAFF MEMBERS, IT'S BEEN A YEAR

2226
01:22:46,016 --> 01:22:49,019
OF CHANGE AND I WANT TO

2227
01:22:49,019 --> 01:22:52,289
ACKNOWLEDGE EVERYONE'S EFFORTS

2228
01:22:52,289 --> 01:22:54,625
IN ADVANCING ORWH, IT'S BEEN A

2229
01:22:54,625 --> 01:22:55,626
TEAM EFFORT.

2230
01:22:55,626 --> 01:22:57,227
DR. HIGGINS HAS A QUESTION?

2231
01:22:57,227 --> 01:22:58,729
>> NOT A QUESTION, BUT A

2232
01:22:58,729 --> 01:23:00,831
COMMENT, I WANT TO COMMEND YOU

2233
01:23:00,831 --> 01:23:02,199
ON YOUR ENTIRE PRESENTATION BUT

2234
01:23:02,199 --> 01:23:04,535
I REALLY LIKE THE QUANTIFICATION

2235
01:23:04,535 --> 01:23:05,903
OF ACCOMPLISH WANTS ISSUES THE

2236
01:23:05,903 --> 01:23:09,440
PUBLICATIONS LICATIONS, THE PATD

2237
01:23:09,440 --> 01:23:12,376
WHAT NOT, I THINK IT'S AN

2238
01:23:12,376 --> 01:23:13,644
IMPORTANT WAY OF SHOWING THE

2239
01:23:13,644 --> 01:23:15,612
CONTRIBUTIONS THAT YOU'RE MAKING

2240
01:23:15,612 --> 01:23:18,649
AND FOR ME, I LOVE THE

2241
01:23:18,649 --> 01:23:20,150
PUBLICATIONS, SO 73,000

2242
01:23:20,150 --> 01:23:21,285
PUBLICATIONS IS PRETERM BIRTH

2243
01:23:21,285 --> 01:23:22,886
IMPEDIMENTS PRESSIVE, SO, I JUST

2244
01:23:22,886 --> 01:23:25,189
WANT TO COMMEND YOU ON THAT.

2245
01:23:25,189 --> 01:23:26,824
>> THANK YOU DR. HIGGINS,
I

2246
01:23:26,824 --> 01:23:27,691
APPRECIATE THE FEEDBACK, WE'RE

2247
01:23:27,691 --> 01:23:31,161
ALWAYS LOOKING AT WAYS TO CONVEY

2248
01:23:31,161 --> 01:23:32,563
THE IMPORTANCE OF WOMEN'S HEALTH

2249
01:23:32,563 --> 01:23:36,233
RESEARCH AND THE IMPORTANCE OF

2250
01:23:36,233 --> 01:23:37,601
NIH WIDE COMPREHENSIVE

2251
01:23:37,601 --> 01:23:39,870
COORDINATED EFFORTS AS

2252
01:23:39,870 --> 01:23:40,170
VALUE-ADDED.

2253
01:23:40,170 --> 01:23:41,972
I APPRECIATE THE FEEDBACK.

2254
01:23:41,972 --> 01:23:45,843
>> LOOKS LIKE DR. ANDERSON
AND

2255
01:23:45,843 --> 01:23:49,513
THEN DR. NOEL. 

2256
01:23:49,513 --> 01:23:50,981
>> YES, DR. ANDERSON,

2257
01:23:50,981 --> 01:23:52,716
DR. CLAYTON THANK YOU VERY MUCH,

2258
01:23:52,716 --> 01:23:54,284
IMPRESSIVE PRESENTATION OF ALL

2259
01:23:54,284 --> 01:23:55,119
ACCOMPLISHED I WAS ENJOYING

2260
01:23:55,119 --> 01:23:55,319
THAT.

2261
01:23:55,319 --> 01:23:56,453
I WAS WONDERING IF YOU COULD

2262
01:23:56,453 --> 01:23:57,588
DESCRIBE SOME OF THE TRANSITIONS

2263
01:23:57,588 --> 01:24:00,391
THAT HAVE HAPPENED IN YOUR

2264
01:24:00,391 --> 01:24:02,226
OFFICE WHICH I THINK OFTEN

2265
01:24:02,226 --> 01:24:03,627
HAPPEN, I WONDER IF THERE HAVE

2266
01:24:03,627 --> 01:24:06,130
BEEN OTHER IMPACTS IN THE ORWH

2267
01:24:06,130 --> 01:24:07,865
THAT YOU COULD DESCRIBE OR HAVE

2268
01:24:07,865 --> 01:24:09,700
THERE BEEN ANY OTHER CHANGES IN

2269
01:24:09,700 --> 01:24:13,037
TERMS OF THE SIZE OF YOUR

2270
01:24:13,037 --> 01:24:14,138
STAFFING, THINGS LIKE THAT THAT

2271
01:24:14,138 --> 01:24:15,973
WOULD AFFECT OUR ABILITY TO MOVE

2272
01:24:15,973 --> 01:24:17,941
FORWARD ON OTHER THINGS?

2273
01:24:17,941 --> 01:24:18,308
>> SURE.

2274
01:24:18,308 --> 01:24:19,810
SO DR. ANDERSON THAT'S AN

2275
01:24:19,810 --> 01:24:21,412
IMPORTANT QUESTION AND IN YOUR

2276
01:24:21,412 --> 01:24:23,380
ROLE AS AN ADVISORY COMMITTEE

2277
01:24:23,380 --> 01:24:24,348
MEMBER, THOSE ARE QUESTIONS THAT

2278
01:24:24,348 --> 01:24:26,250
ARE IMPORTANT FOR YOU TO

2279
01:24:26,250 --> 01:24:27,184
UNDERSTAND OUR ABILITY TO GET

2280
01:24:27,184 --> 01:24:29,019
OUR JOB DONE IN THE

2281
01:24:29,019 --> 01:24:29,486
INTERMISSION.

2282
01:24:29,486 --> 01:24:31,789
SO THERE HAS -- IT IS A CHANGING

2283
01:24:31,789 --> 01:24:32,890
LANDSCAPE AND WE DO HAVE

2284
01:24:32,890 --> 01:24:35,893
POSITIONS THAT ARE OPEN AT THIS

2285
01:24:35,893 --> 01:24:37,628
TIME AND SO IT'S IMPORTANT FOR

2286
01:24:37,628 --> 01:24:41,031
US TO ALWAYS BE AS EFFICIENT AS

2287
01:24:41,031 --> 01:24:43,567
POSSIBLE AND FOCUS ON OUR

2288
01:24:43,567 --> 01:24:51,942
CRITICAL VALUE ADDED THAT ONLY

2289
01:24:51,942 --> 01:24:54,611
ORWH CAN DO, AND WITH FEWER

2290
01:24:54,611 --> 01:24:56,013
STAFFING AND OUR TEAM SIZE, THAT

2291
01:24:56,013 --> 01:24:57,448
DOES MAKE THAT MORE CHALLENGING

2292
01:24:57,448 --> 01:24:59,516
OF OF COURSE WE ARE FIRMLY

2293
01:24:59,516 --> 01:25:03,287
COMMITTED TO ADVANCING EVERY

2294
01:25:03,287 --> 01:25:04,688
SINGLE ORWH SIGNATURE PROGRAM

2295
01:25:04,688 --> 01:25:09,026
AND WE'VE CHOSEN TO FOCUS ON

2296
01:25:09,026 --> 01:25:10,761
THOSE SIGNATURE PROGRAMS AS OUR

2297
01:25:10,761 --> 01:25:12,496
NUMBER 1 PRIORITY OF OF COURSE

2298
01:25:12,496 --> 01:25:14,131
EACH AND EVERY 1 OF THEM ARE

2299
01:25:14,131 --> 01:25:15,466
DONE IN COLLABORATION WITH AN

2300
01:25:15,466 --> 01:25:15,999
INSTITUTE OR CENTER.

2301
01:25:15,999 --> 01:25:20,604
SO WE HAVE GOOD NEWS AS A NEW

2302
01:25:20,604 --> 01:25:24,074
PARTNERS, WITH NIAMS, WITH THE

2303
01:25:24,074 --> 01:25:25,943
BIRCWH FOR THAT, WE HAVE NEW

2304
01:25:25,943 --> 01:25:28,011
NEWS COMING, I CAN'T SHARE JUST

2305
01:25:28,011 --> 01:25:29,646
YET, PART MERSHIP OUTSIDE OF

2306
01:25:29,646 --> 01:25:32,516
NIH, OUR SCORE PROGRAM CONTINUES

2307
01:25:32,516 --> 01:25:37,454
TO BE STRONG, SABB, AS YOU HEARD

2308
01:25:37,454 --> 01:25:39,623
FROM DR. KLEINSTREUER, CONTINUES

2309
01:25:39,623 --> 01:25:40,924
TO BE SUPPORTED AND WOMEN'S

2310
01:25:40,924 --> 01:25:42,559
HEALTH CONTINUES TO BE A

2311
01:25:42,559 --> 01:25:43,127
PRIORITY.

2312
01:25:43,127 --> 01:25:44,261
AS WE MOVE FORWARD IT WILL BE

2313
01:25:44,261 --> 01:25:45,562
IMPORTANT THAT WE ARE ABLE TO

2314
01:25:45,562 --> 01:25:47,064
BRING BACK UPDATES TO YOU ON OUR

2315
01:25:47,064 --> 01:25:50,567
ABILITY TO MOVE FORWARD WITH OUR

2316
01:25:50,567 --> 01:25:52,369
PROGRAMS AND GIVE YOU THE

2317
01:25:52,369 --> 01:25:54,972
INFORMATION YOU NEED TO BE ABLE

2318
01:25:54,972 --> 01:25:57,841
TO PROVIDE TO US AS OUR ADVISORY

2319
01:25:57,841 --> 01:25:58,108
MEMBERS.

2320
01:25:58,108 --> 01:25:59,610
SO WE APPRECIATE ANY THOUGHTS

2321
01:25:59,610 --> 01:26:01,278
YOU MIGHT HAVE ON WAYS YOU WE

2322
01:26:01,278 --> 01:26:02,980
CAN MOVE FORWARD AND WHAT MIGHT

2323
01:26:02,980 --> 01:26:04,982
BE TOP OF MIND FOR YOU ALLA THIS

2324
01:26:04,982 --> 01:26:13,023
TIME AS MOST CRITICAL TO

2325
01:26:13,023 --> 01:26:18,295
ADDRESS. 

2326
01:26:18,295 --> 01:26:19,163
>> THANK YOU.

2327
01:26:19,163 --> 01:26:21,431
>> WAS THERE ANOTHER HAND?

2328
01:26:21,431 --> 01:26:23,133
I THOUGHT DR. NOEL HAD HEAR HAND

2329
01:26:23,133 --> 01:26:25,302
UP BUT MAYBE THAT WASN'T THE

2330
01:26:25,302 --> 01:26:27,137
LEGACY HAND.

2331
01:26:27,137 --> 01:26:29,940
>> WELL YOU ACTUALLY --
HI,

2332
01:26:29,940 --> 01:26:30,607
ALEXANDRA NOEL, YOUY SPONDY

2333
01:26:30,607 --> 01:26:32,476
LIGHTISSED A BIT TO MY QUESTION.

2334
01:26:32,476 --> 01:26:34,111
I THINK YOU HAD A NICE

2335
01:26:34,111 --> 01:26:37,481
PRESENTATION AND YOU SHOWED THAT

2336
01:26:37,481 --> 01:26:39,550
THERE WAS SEX BASED DIFFERENCE

2337
01:26:39,550 --> 01:26:43,887
EVEN IN UTERO LOOKING AT THE

2338
01:26:43,887 --> 01:26:46,523
PLACENTA FOR MALE FETUSES,

2339
01:26:46,523 --> 01:26:47,457
VERSUS FEMALE FETUSES AND I

2340
01:26:47,457 --> 01:26:49,092
WANTED TO KNOW WHETHER IT WOULD

2341
01:26:49,092 --> 01:26:51,895
BE A RESEARCH PRIORITY TO LOOK

2342
01:26:51,895 --> 01:26:54,298
AT EPIGENETIC EFFECTS IN THE

2343
01:26:54,298 --> 01:26:56,333
PLACENTA AND SEX BASED

2344
01:26:56,333 --> 01:26:57,801
DIFFERENCE IN THE OFFSPRING,

2345
01:26:57,801 --> 01:27:01,238
WOULD THAT BE A PRIORITY MOVING

2346
01:27:01,238 --> 01:27:01,605
FORWARD?

2347
01:27:01,605 --> 01:27:05,309
>> SO EPIGENETIC SEX
DIFFERENCES

2348
01:27:05,309 --> 01:27:07,477
ARE REALLY, I THINK AN AREA OF

2349
01:27:07,477 --> 01:27:07,911
OPPORTUNITY.

2350
01:27:07,911 --> 01:27:09,646
I VBT SEEN A HUGE AMOUNT OF

2351
01:27:09,646 --> 01:27:11,081
ATTENTION TO THAT WHICH IS 1 OF

2352
01:27:11,081 --> 01:27:13,116
THE REASONS I HIGHLIGHTED THAT

2353
01:27:13,116 --> 01:27:14,418
PARTICULAR STUDY, AND YOU SAW

2354
01:27:14,418 --> 01:27:16,553
HOW IMPORTANT IT IS, I DIDN'T

2355
01:27:16,553 --> 01:27:18,555
EMPHASIZE, YOU KNOW WITH TIME

2356
01:27:18,555 --> 01:27:22,359
LIMITATIONS THAT THOSE SEX

2357
01:27:22,359 --> 01:27:24,795
DIFFERENCES ARE AND METHYLATION

2358
01:27:24,795 --> 01:27:26,830
PATTERNS ARE NEAR GENES THAT

2359
01:27:26,830 --> 01:27:28,966
REALLY ARE LINKED TO CHRONIC

2360
01:27:28,966 --> 01:27:30,367
DISEASE DEVELOPMENT OF THOSE

2361
01:27:30,367 --> 01:27:32,369
OFFSPRING SO IF WE CAN BETTER

2362
01:27:32,369 --> 01:27:33,470
UNDERSTAND HOW SEX DIFFERENCES

2363
01:27:33,470 --> 01:27:34,605
AND METHYLATION PAT

2364
01:27:34,605 --> 01:27:37,774
E-PRESCRIBINGS AND MA SENTA OR

2365
01:27:37,774 --> 01:27:39,743
OTHERWISE, SET UP, SET US UP

2366
01:27:39,743 --> 01:27:40,944
MALES AND FEMALES FOR THE

2367
01:27:40,944 --> 01:27:41,645
DEVELOPMENT OF CHRONIC DISEASE,

2368
01:27:41,645 --> 01:27:43,614
THAT WOULD BE A HUGE INSIGHT

2369
01:27:43,614 --> 01:27:45,916
INTO THE ARC OF CHRONIC DISEASE

2370
01:27:45,916 --> 01:27:48,852
DEVELOPMENT AND SO, FROM THE

2371
01:27:48,852 --> 01:27:50,387
LIFE FORCE PERSPECTIVE WE SEE IT

2372
01:27:50,387 --> 01:27:55,292
AS A PRIORITY AND WE SEE THAT

2373
01:27:55,292 --> 01:27:57,928
SABB, -- IT'S REALLY A GREAT

2374
01:27:57,928 --> 01:27:59,096
EXAMPLE OF SABB IN ACTION.

2375
01:27:59,096 --> 01:28:01,865
SO WHETHER THAT'S TAKEN UP FROM

2376
01:28:01,865 --> 01:28:02,499
1 PARTICULAR INSTITUTE'S

2377
01:28:02,499 --> 01:28:05,669
PERSPECTIVE, I THINK THIS IS AN

2378
01:28:05,669 --> 01:28:09,006
ISSUE FOR ALL OF NIH, FOR ANY OF

2379
01:28:09,006 --> 01:28:11,608
THE INSTITUTES THAT HAVE

2380
01:28:11,608 --> 01:28:12,376
DEVELOPMENTAL AND HEALTH

2381
01:28:12,376 --> 01:28:14,044
DISEASEADS PART OF THEIR MISSION

2382
01:28:14,044 --> 01:28:15,145
TO ACCOUNT FOR SABB, THAT NEEDS

2383
01:28:15,145 --> 01:28:16,179
TO BE PART OF IT.

2384
01:28:16,179 --> 01:28:18,148
SO ONCE WE KNOW SEX HAS AN

2385
01:28:18,148 --> 01:28:19,716
AFFECT, YOU NEED TO,A COUNT FOR

2386
01:28:19,716 --> 01:28:21,518
IT IN FUTURE STUDIES BECAUSE NOW

2387
01:28:21,518 --> 01:28:23,253
WE UNDERSTAND THAT HAS AN AFFECT

2388
01:28:23,253 --> 01:28:25,322
WE WANT TO UNDERSTAND HOW YOU'RE

2389
01:28:25,322 --> 01:28:26,623
ACCOUNTING FOR THAT IN THAT NEXT

2390
01:28:26,623 --> 01:28:28,025
STUDY SO WE CAN BUILD ON THAT

2391
01:28:28,025 --> 01:28:29,426
KNOWLEDGE BASE, SO HOPE TO SEE,

2392
01:28:29,426 --> 01:28:33,363
YOU KNOW MORE STUDIES BUILDING

2393
01:28:33,363 --> 01:28:35,399
UPON THAT AMAZING COVERAGE

2394
01:28:35,399 --> 01:28:39,469
FUNDED BY NICHD AND OF COURSE

2395
01:28:39,469 --> 01:28:40,637
OTHERS, GTEX AND OTHERS HAVE

2396
01:28:40,637 --> 01:28:42,105
LOOKED AT SEX DIFFERENCES IN

2397
01:28:42,105 --> 01:28:43,907
GENE EXPRESSION BUT TRYING TO

2398
01:28:43,907 --> 01:28:45,309
UNDERSTAND WHAT THE DIFFERENCE

2399
01:28:45,309 --> 01:28:47,711
IS, THE ETIOLOGY OF THOSE SEX

2400
01:28:47,711 --> 01:28:50,547
DIFFERENCES AND THE UNDERLYING

2401
01:28:50,547 --> 01:28:51,548
PATHOGIZZIOLOGY OF COMPLEX

2402
01:28:51,548 --> 01:28:52,516
DIFFERENCES IN GENE EXPRESSION

2403
01:28:52,516 --> 01:28:54,318
EMPLOY WE REALLY HAVE A LOT TO

2404
01:28:54,318 --> 01:29:04,761
LEARN AND OF COURSE GREAT

2405
01:29:06,730 --> 01:29:07,397
QUESTION, ALEXANDRA.

2406
01:29:07,397 --> 01:29:08,632
>> OKAY, THAIRNG YOU SO
MUCH FOR

2407
01:29:08,632 --> 01:29:10,701
YOUR INTEREST, YOUR QUESTIONS,

2408
01:29:10,701 --> 01:29:15,005
YOUR LONG STANDING ACWRH MEMBERS

2409
01:29:15,005 --> 01:29:17,908
I AM ALWAYS EXCITED TO BRING IT

2410
01:29:17,908 --> 01:29:19,676
TO YOU.

2411
01:29:19,676 --> 01:29:20,711
DR. OTA WANG WOULD YOU LIKE ME

2412
01:29:20,711 --> 01:29:22,913
TO MOVE ON AND INTRODUCE OUR

2413
01:29:22,913 --> 01:29:23,547
NEXT SPEAKER?

2414
01:29:23,547 --> 01:29:24,114
>> PLEASE DO.

2415
01:29:24,114 --> 01:29:28,051
>> I AM VERY EXCITED TO

2416
01:29:28,051 --> 01:29:30,387
INTRODUCE DR. DI NA P A LTO,

2417
01:29:30,387 --> 01:29:32,255
EACH OF THESE MEETINGS WE WANT

2418
01:29:32,255 --> 01:29:33,323
TO PRESENT THEIR PERSPECTIVE SO

2419
01:29:33,323 --> 01:29:34,858
YOU CAN UNDERSTAND HOW ALL THE

2420
01:29:34,858 --> 01:29:36,493
INSTITUTES AND CENTERS ARE

2421
01:29:36,493 --> 01:29:37,561
WORKING TOWARD IMPROVING THE

2422
01:29:37,561 --> 01:29:39,830
HELT OF WOMEN.

2423
01:29:39,830 --> 01:29:45,302
DR. DINA P A LTOO, IS THE ACTING

2424
01:29:45,302 --> 01:29:47,070
DEPUTY DIRECTOR OF POLICY AND

2425
01:29:47,070 --> 01:29:48,805
EXTERNAL AFFAIRS AT NLM, IN THIS

2426
01:29:48,805 --> 01:29:51,708
ROLE, SHE IS THE ROLE TO THE

2427
01:29:51,708 --> 01:29:53,677
SENIOR ADVISORY DIRECTOR OF NLP

2428
01:29:53,677 --> 01:29:55,612
AND ESTABLISHES FRAMEWORK

2429
01:29:55,612 --> 01:29:56,880
THAGOREAN GUIDES NLM'S RESEARCH,

2430
01:29:56,880 --> 01:29:57,514
OPERATION AND PUB LIBRARY

2431
01:29:57,514 --> 01:29:59,216
FOUNDATION SERVICES AND WORKING

2432
01:29:59,216 --> 01:30:01,017
ALONG NLM'S DEPUTY DIRECTOR FOR

2433
01:30:01,017 --> 01:30:03,153
OPERATIONS AND INNOVATION.

2434
01:30:03,153 --> 01:30:05,355
SHE ALSO OVERSEES NLM'S

2435
01:30:05,355 --> 01:30:08,525
RELATIONSHIPS ACROSS THE NIH

2436
01:30:08,525 --> 01:30:09,993
INCLUDING ORWH AND WITH EXTERNAL

2437
01:30:09,993 --> 01:30:10,327
GROUPS.

2438
01:30:10,327 --> 01:30:12,429
SHE WAS RENTLY DIRECTOR FOR

2439
01:30:12,429 --> 01:30:14,064
SCIENTIFIC STRATEGY AND

2440
01:30:14,064 --> 01:30:15,999
INNOVATION AT NHLBI WHERE SHE

2441
01:30:15,999 --> 01:30:18,135
SERVED AS SENIOR ADVISOR TO THE

2442
01:30:18,135 --> 01:30:20,437
NHLBI DIRECTOR AND SHE HAS

2443
01:30:20,437 --> 01:30:28,345
PREVIOUSLY SERVED AS NLM AS THE

2444
01:30:28,345 --> 01:30:29,746
ASSISTANT DIRECTOR FOR PRIORITY

2445
01:30:29,746 --> 01:30:30,714
DEVELOPMENT.

2446
01:30:30,714 --> 01:30:33,650
PRIOR TO JOINING NLM, SHE WAS

2447
01:30:33,650 --> 01:30:34,684
DIRECTOR OF THE SCIENTIFIC

2448
01:30:34,684 --> 01:30:35,952
POLICY AND HEALTH AND SOCIETY

2449
01:30:35,952 --> 01:30:37,621
PROGRAM WESTBOUND THE NIH OFFICE

2450
01:30:37,621 --> 01:30:39,556
OF THE DIRECTOR'S OFFICE OF

2451
01:30:39,556 --> 01:30:41,825
SCIENCE POLICY, RSP AND WAS

2452
01:30:41,825 --> 01:30:42,993
RESPONSIBLE FOR MNIH POLICY

2453
01:30:42,993 --> 01:30:43,894
EFFORTS AND ETHICAL

2454
01:30:43,894 --> 01:30:44,828
CONSIDERATIONS IN SCIENTIFIC

2455
01:30:44,828 --> 01:30:47,230
DATA SHARING AND MANAGEMENT,

2456
01:30:47,230 --> 01:30:50,267
OPEN SCIENCE, AND GENOMICS AND

2457
01:30:50,267 --> 01:30:50,500
HEALTH.

2458
01:30:50,500 --> 01:30:52,636
SHE HAS SERVE AS A PROGRAM

2459
01:30:52,636 --> 01:30:54,438
DIRECTOR AT NHLBI AND MAINTAINS

2460
01:30:54,438 --> 01:30:56,373
SCIENTIFIC PORTFOLIOS IN THE

2461
01:30:56,373 --> 01:30:57,908
PAST RELATED TO GENETICS PHARMA

2462
01:30:57,908 --> 01:30:59,976
CO GENETICS AND PERSONALIZED

2463
01:30:59,976 --> 01:31:01,845
MEDICINE AND YOU CAN SEE WHY WE

2464
01:31:01,845 --> 01:31:04,247
INVITED HERE HERE TODAY, SHE DID

2465
01:31:04,247 --> 01:31:05,949
RECEIVE HER BACHELOR OF

2466
01:31:05,949 --> 01:31:08,351
SUBSTANCE IN MICROBIOLOGY AND

2467
01:31:08,351 --> 01:31:10,854
Ph.D. IN PHYSICS FROM HOWARD

2468
01:31:10,854 --> 01:31:12,956
UNIVERSITY AND MD FROM JOHNS

2469
01:31:12,956 --> 01:31:14,891
HOPKINS SCHOOL OF PUBLIC HEALTH

2470
01:31:14,891 --> 01:31:17,994
AS WELL AS CERTIFICATES AND

2471
01:31:17,994 --> 01:31:19,563
MEDICINE AND NEW JERSEY AND

2472
01:31:19,563 --> 01:31:21,398
ALUMNI OF THE CANCER PREVENTION

2473
01:31:21,398 --> 01:31:23,867
FELLOWSHIP PROGRAM HERE AT THE

2474
01:31:23,867 --> 01:31:25,969
NATIONAL CANCER INSTITUTE.

2475
01:31:25,969 --> 01:31:28,405
PLEASE JOIN ME IN WELCOMING

2476
01:31:28,405 --> 01:31:32,943
DR. DINA P A LTOO.

2477
01:31:32,943 --> 01:31:35,345
>> THANK YOU SO MUCH

2478
01:31:35,345 --> 01:31:35,679
DR. CLAYTON.

2479
01:31:35,679 --> 01:31:37,881
AS DR. CLAYTON MENTIONED MY NAME

2480
01:31:37,881 --> 01:31:40,784
IS DINA P A LTOOI AM THE DEPUTY

2481
01:31:40,784 --> 01:31:42,953
DIRECTOR FOR POLICY AND EXTERNAL

2482
01:31:42,953 --> 01:31:43,954
AFFAIRS AT NLM.

2483
01:31:43,954 --> 01:31:45,689
I AM VERY HAPPY TO BE HERE AND

2484
01:31:45,689 --> 01:31:46,723
EXCITED TO HAVE THE OPPORTUNITY

2485
01:31:46,723 --> 01:31:48,725
TO SHARE WITH YOU A LITTLE

2486
01:31:48,725 --> 01:31:49,559
BACKGROUNDOT NATIONAL LIBRARY OF

2487
01:31:49,559 --> 01:31:49,860
MEDICINE.

2488
01:31:49,860 --> 01:31:52,128
I KNOW A LOT OF YOU MAY NOT BE

2489
01:31:52,128 --> 01:31:53,196
FAMILIAR WITH WHO WE ARE AND

2490
01:31:53,196 --> 01:31:54,831
WHAT WE DO, BUT I WOULD ALSO

2491
01:31:54,831 --> 01:31:57,334
LIKE TO TAKE TO YOU A LITTLE BIT

2492
01:31:57,334 --> 01:31:59,069
ABOUT HOW NLM ADVANCES

2493
01:31:59,069 --> 01:32:00,804
BIOMEDICAL RESEARCH AT THE

2494
01:32:00,804 --> 01:32:05,809
INTERSECTION OF DATA SCIENCE AND

2495
01:32:05,809 --> 01:32:06,510
INFORMATION. 

2496
01:32:06,510 --> 01:32:13,416
NEXT SLIDE, PLEASE.

2497
01:32:13,416 --> 01:32:15,151
I KNOW A LOT OF YOU KNOW THIS

2498
01:32:15,151 --> 01:32:16,887
ALREADY BUT TO PROVIDE A BIT OF

2499
01:32:16,887 --> 01:32:18,221
CONTEXT, UP IN THE WOMEN'S

2500
01:32:18,221 --> 01:32:20,257
RIGHTS MOVEMENT OF THE 1960INGS,

2501
01:32:20,257 --> 01:32:21,892
HEALTHCARE FOR WOMEN AND

2502
01:32:21,892 --> 01:32:23,827
RESEARCH INTO WOMEN'S HEALTH

2503
01:32:23,827 --> 01:32:25,195
ISSUES HAD HISTORICALLY LACKED

2504
01:32:25,195 --> 01:32:26,863
BEHIND THOSE FOR MEN AND AS

2505
01:32:26,863 --> 01:32:28,365
THOSE MOVEMENTS REACHED THE

2506
01:32:28,365 --> 01:32:31,434
NATIONAL STAGE, SO DID THE

2507
01:32:31,434 --> 01:32:33,637
ENTRENCHED DISPARITIES OF WOMEN

2508
01:32:33,637 --> 01:32:35,138
SPECIFIC CARE, ACCESS AND

2509
01:32:35,138 --> 01:32:36,506
RESEARCH, HOWEVER, DISSPITE THE

2510
01:32:36,506 --> 01:32:39,175
VISIBILITY AND HELP OF VOCAL

2511
01:32:39,175 --> 01:32:41,545
ADVOCATES ACROSS COMMUNITIES IN

2512
01:32:41,545 --> 01:32:43,813
RESEARCH MEDICINE AND POLICY

2513
01:32:43,813 --> 01:32:46,316
THESE DISPARITIES REMAIN EVEN

2514
01:32:46,316 --> 01:32:47,150
TODAY.

2515
01:32:47,150 --> 01:32:49,419
FOR EXAMPLE, IN 2019, WOMEN

2516
01:32:49,419 --> 01:32:51,788
ACCOUNTED FOR ABOUT 40% OF

2517
01:32:51,788 --> 01:32:54,324
PARTICIPANTS IN CLINICAL TRIALS

2518
01:32:54,324 --> 01:32:55,792
ON CANCER, KASHEDIO VASCULAR

2519
01:32:55,792 --> 01:32:57,627
DISEASE AWELL AS PSYCHIATRIC

2520
01:32:57,627 --> 01:32:59,663
DISORDERS AND AS YOU HEARD

2521
01:32:59,663 --> 01:33:02,365
PREVIOUSLY TODAY, THESE 3

2522
01:33:02,365 --> 01:33:03,733
DISEASES PRIMARILY OR

2523
01:33:03,733 --> 01:33:05,802
DIFFERENTLY AFFECT WOMEN DESPITE

2524
01:33:05,802 --> 01:33:08,538
WOMEN REPRESENTING OVER HALF THE

2525
01:33:08,538 --> 01:33:09,639
POPULATION.

2526
01:33:09,639 --> 01:33:11,408
BUT WHAT'S MORE, BECAUSE MANY OF

2527
01:33:11,408 --> 01:33:13,410
THESE TRIALS DIDN'T ACCOUNT FOR

2528
01:33:13,410 --> 01:33:15,045
THE INTERSECTION OF SEX AND

2529
01:33:15,045 --> 01:33:17,614
RACE, WOMEN WERE LESS LIKELY TO

2530
01:33:17,614 --> 01:33:19,115
BE REPRESENTED IN CLINICAL

2531
01:33:19,115 --> 01:33:24,588
TRIALS AT ALL. 

2532
01:33:24,588 --> 01:33:25,689
NEXT SLIDE, PLEASE.

2533
01:33:25,689 --> 01:33:27,524
SO THIS SLIDE PROVIDES IMPORTANT

2534
01:33:27,524 --> 01:33:29,359
MILESTONES IN SUPPORT OF

2535
01:33:29,359 --> 01:33:30,594
RESEARCH ON WOMEN'S HEALTH THAT

2536
01:33:30,594 --> 01:33:31,761
YOU'RE ALL FAMILIAR WITH.

2537
01:33:31,761 --> 01:33:33,964
THE SLIDE IS FAR FROM

2538
01:33:33,964 --> 01:33:37,367
COMPREHENSIVE BUT AS YOU KNOW

2539
01:33:37,367 --> 01:33:38,802
NIH ESTABLISHED THE NIH OFFICE

2540
01:33:38,802 --> 01:33:41,938
OF RESEARCH ON WOMEN'S HEALTH IN

2541
01:33:41,938 --> 01:33:45,609
1990 TO SERVE AS A FOCAL POINT

2542
01:33:45,609 --> 01:33:47,477
TO ENHANCE AND EXPAND WOMEN'S

2543
01:33:47,477 --> 01:33:49,045
RESEARCH AND INCLUDE RESEARCH

2544
01:33:49,045 --> 01:33:50,013
POPULATIONS AND ALSO CONSIDER

2545
01:33:50,013 --> 01:33:51,881
SEX AS A FACTOR IN HELT AND

2546
01:33:51,881 --> 01:33:52,782
DISEASE.

2547
01:33:52,782 --> 01:33:55,652
SEVERAL YEARS LATER, THE U.S.

2548
01:33:55,652 --> 01:33:57,487
FOOD AND DRUG ADMINISTRATION

2549
01:33:57,487 --> 01:33:58,288
OFFICIALLY MANDATED THE

2550
01:33:58,288 --> 01:34:02,759
INCLUSION OF WOMEN IN RESEARCH

2551
01:34:02,759 --> 01:34:06,930
AND THEN WITH THE NIH

2552
01:34:06,930 --> 01:34:07,998
REVITALIZATION ACT, THIS MANDATE

2553
01:34:07,998 --> 01:34:09,099
WAS EVENTUALLY SIGNED INTO LAW.

2554
01:34:09,099 --> 01:34:11,568
AND TO COMPLY WITH THIS ACT, NIH

2555
01:34:11,568 --> 01:34:12,636
PUBLISHED GUIDELINES THAT

2556
01:34:12,636 --> 01:34:14,137
RESEARCH REQUIRED RESEARCHERS TO

2557
01:34:14,137 --> 01:34:16,106
INCLUDE WOMEN AND MINORITIES IN

2558
01:34:16,106 --> 01:34:17,741
THEIR SUBPOPULATIONS IN THEIR

2559
01:34:17,741 --> 01:34:19,075
CLIENICAL RESEARCH.

2560
01:34:19,075 --> 01:34:25,215
AND AS DR. KLEINSTEURER, WITH

2561
01:34:25,215 --> 01:34:27,550
THE 21st CENTURY CURES ACT,

2562
01:34:27,550 --> 01:34:29,285
THESE GUIDELINES EXPANDED TO

2563
01:34:29,285 --> 01:34:29,986
INCLUDE RESEARCHERS AND

2564
01:34:29,986 --> 01:34:32,956
INCLUDING INFORMATION ON SEX,

2565
01:34:32,956 --> 01:34:35,725
RACE AND ETHNICITY IN PHASE 3

2566
01:34:35,725 --> 01:34:41,898
CLINICAL TRIALS ON  CLINICAL

2567
01:34:41,898 --> 01:34:43,099
TRIALS .GOV.

2568
01:34:43,099 --> 01:34:48,171
IT IS MAINTAINED BY NLM, AND IT

2569
01:34:48,171 --> 01:34:52,642
A SOURCE FOR INFORMATION ON

2570
01:34:52,642 --> 01:34:52,876
RESULTS.

2571
01:34:52,876 --> 01:34:55,979
IN 2023, CONGRESS DIRECTED NIH

2572
01:34:55,979 --> 01:34:58,348
TO ESTABLISH THE OFFICE OF

2573
01:34:58,348 --> 01:35:04,988
AUTOIMMUNE DISEASE RESEARCH IN

2574
01:35:04,988 --> 01:35:06,056
ORWH AND NLM PARTICIPATES IN

2575
01:35:06,056 --> 01:35:07,157
THEA BEINGIVITYS OF THE THIS

2576
01:35:07,157 --> 01:35:08,992
OFFICE AND THERE'S ALSO THE

2577
01:35:08,992 --> 01:35:10,060
DEVELOPING THE REPORT AND

2578
01:35:10,060 --> 01:35:11,227
STRATEGIC PLAN THAT YOU HEARD

2579
01:35:11,227 --> 01:35:15,598
HEARD ABOUT.

2580
01:35:15,598 --> 01:35:16,266
NEXT SLIDE.

2581
01:35:16,266 --> 01:35:19,469
SO OVER THE YEARS AND AS

2582
01:35:19,469 --> 01:35:22,706
HIGHLIGHTED BY DR. CLAYTON, ORWH

2583
01:35:22,706 --> 01:35:24,107
HAS WORKED IN PARTNERSHIP WITH

2584
01:35:24,107 --> 01:35:25,842
INSTITUTES AND CENTERS ACROSS

2585
01:35:25,842 --> 01:35:27,177
THE NIH INCLUDING THE NATIONAL

2586
01:35:27,177 --> 01:35:29,145
LIBRARY OF MEDICINE WHICH IS 1

2587
01:35:29,145 --> 01:35:32,215
OF NIH'S 27 INSTITUTES AND

2588
01:35:32,215 --> 01:35:35,218
CENTERS, AND NLM SERVEs AS A

2589
01:35:35,218 --> 01:35:35,885
PLATFORM FOR BIOMEDICAL

2590
01:35:35,885 --> 01:35:40,757
DISCOVERY AND DATA POWERED

2591
01:35:40,757 --> 01:35:42,325
HEALTH BY ACCELERATING EXCUSE

2592
01:35:42,325 --> 01:35:44,527
ME, DISCOVERY AND ADVANCE HEALTH

2593
01:35:44,527 --> 01:35:45,462
DATA DRIVEN RESEARCH, AND

2594
01:35:45,462 --> 01:35:47,530
REACHING MORE PEOPLE AND MORE

2595
01:35:47,530 --> 01:35:48,832
WAYS THROUGH ENHANCED

2596
01:35:48,832 --> 01:35:49,666
DISSEMINATION AND ENGAGEMENT AND

2597
01:35:49,666 --> 01:35:52,268
ALSO BY BUILDING A WORK FOR FOR

2598
01:35:52,268 --> 01:35:53,136
DATA DRIVEN EXPRCH HEALTH.

2599
01:35:53,136 --> 01:35:54,537
AND TODAY WE WOULD LIKE TO TALK

2600
01:35:54,537 --> 01:35:57,273
A LITTLE BIT ABOUT HOW NLM'S

2601
01:35:57,273 --> 01:35:59,242
HISTORY AND ITS EVOLVING ROLE IN

2602
01:35:59,242 --> 01:36:00,977
DATA DRIVEN APPROACHES TO

2603
01:36:00,977 --> 01:36:02,245
ADVANCING WOMEN'S HEALTH AS WELL

2604
01:36:02,245 --> 01:36:04,347
AS FROM MAKING THAT RESEARCH

2605
01:36:04,347 --> 01:36:05,482
MORE DISCOVERABLE, AND

2606
01:36:05,482 --> 01:36:07,050
ACCESSIBLE AND ALSO INSURING

2607
01:36:07,050 --> 01:36:08,518
THAT WOMEN ARE REPRESENTED NOT

2608
01:36:08,518 --> 01:36:10,487
JUST IN THE DATA AND

2609
01:36:10,487 --> 01:36:12,288
INFORMATION, BUT ALSO BEHIND THE

2610
01:36:12,288 --> 01:36:15,992
SCIENCE. 

2611
01:36:15,992 --> 01:36:18,261
NEXT SLIDE, PLEASE.

2612
01:36:18,261 --> 01:36:20,897
NLM IS DIVIDED INTO 5 OFFICES,

2613
01:36:20,897 --> 01:36:23,333
AND DIVISIONS THAT EACH MANAGE

2614
01:36:23,333 --> 01:36:25,268
OUR RESOURCES FROM DIVISION OF

2615
01:36:25,268 --> 01:36:27,303
INTRAMURAL RESEARCH IN WHICH WE

2616
01:36:27,303 --> 01:36:28,238
HOUSE PRINCIPLE INVESTIGATORS

2617
01:36:28,238 --> 01:36:30,306
AND THEY SHOWCASE THEIR

2618
01:36:30,306 --> 01:36:33,109
INNOVATIVE SPIRIT AND PASSION

2619
01:36:33,109 --> 01:36:34,744
FOR BIOMEDICAL RESEARCH TO OUR

2620
01:36:34,744 --> 01:36:38,615
LISTER HILL CENTER FOR

2621
01:36:38,615 --> 01:36:42,585
BIOMEDICAL COMMUNICATIONS WHICH

2622
01:36:42,585 --> 01:36:44,354
FOCUSES ON ADVANCEMENT AND

2623
01:36:44,354 --> 01:36:45,188
RESEARCH, AND ACHIEVING

2624
01:36:45,188 --> 01:36:46,823
INCREDIBLE AREY SULTS ACROSS

2625
01:36:46,823 --> 01:36:48,925
INFORMATION AND DATA

2626
01:36:48,925 --> 01:36:49,292
BIO-INFORMATICS.

2627
01:36:49,292 --> 01:36:50,226
NLM IS A LITTLE DIFFERENT THAN

2628
01:36:50,226 --> 01:36:53,696
MOST INSTITUTES AND CENTERS AT

2629
01:36:53,696 --> 01:36:55,799
NIH IN THAT OUR BUDGET FOR OUR

2630
01:36:55,799 --> 01:36:58,034
WORK IS APPROXIMATELY 80% FOR

2631
01:36:58,034 --> 01:37:00,570
IMPOSSIBLE TO BUILD RAMURAL AND

2632
01:37:00,570 --> 01:37:06,409
20% FOR EXTRAMURAL RESEARCH. 

2633
01:37:06,409 --> 01:37:07,076
NEXT SLIDE, PLEASE.

2634
01:37:07,076 --> 01:37:10,313
UNDER THE ACTING DIRECTORSHIP OF

2635
01:37:10,313 --> 01:37:11,681
STEF SHERRY, NLM'S SUCCESS IS

2636
01:37:11,681 --> 01:37:14,150
DRIVEN IN PART BY DEDICATED

2637
01:37:14,150 --> 01:37:14,951
SENIOR LEADERSHIP TEAM WHO

2638
01:37:14,951 --> 01:37:16,386
COORDINATE AND SEE THE EXECUTION

2639
01:37:16,386 --> 01:37:18,488
OF OUR PRODUCT SERVICES AND

2640
01:37:18,488 --> 01:37:19,422
OTHER OFFERINGS.

2641
01:37:19,422 --> 01:37:22,258
WE WORK ACROSS NIH TO

2642
01:37:22,258 --> 01:37:23,526
COLLABORATE ON IMPORTANT

2643
01:37:23,526 --> 01:37:24,794
INITIATIVE ANDS PROVIDE SUBJECT

2644
01:37:24,794 --> 01:37:27,096
MATTER EXPERT EEDZ INIARYS SUCH

2645
01:37:27,096 --> 01:37:30,166
AS HEALTH IT, STANDARDS,

2646
01:37:30,166 --> 01:37:31,434
BIO-INFORMATICS, PUBLIC ACCESS

2647
01:37:31,434 --> 01:37:33,303
TO DATA AND PUBLICATIONS AND AS

2648
01:37:33,303 --> 01:37:41,010
WELL AS DATA SCIENCE. 

2649
01:37:41,010 --> 01:37:42,378
NEXT SLIDE, PLEASE.

2650
01:37:42,378 --> 01:37:44,848
NLM WAS ESTABLISHED IN 1836 AS A

2651
01:37:44,848 --> 01:37:46,149
SMALL COLLECTION OF MEDICAL

2652
01:37:46,149 --> 01:37:47,450
BOOKS IN THE OFFICE OF THE

2653
01:37:47,450 --> 01:37:49,519
SURGEON GENERAL OF ARMY AND HAS

2654
01:37:49,519 --> 01:37:51,754
EVOLVED INTO A NATIONAL RESOURCE

2655
01:37:51,754 --> 01:37:56,860
FOR BIOMEDICAL  INFORMATION AND

2656
01:37:56,860 --> 01:38:02,899
THE WORLD'S LARGEST BIOMEDICAL

2657
01:38:02,899 --> 01:38:07,303
LIBRARY AND DEVELOPER OF

2658
01:38:07,303 --> 01:38:09,138
ADVANCED BIOMEDICAL INFORMATION

2659
01:38:09,138 --> 01:38:10,406
SERVICES THIS INCLUDES

2660
01:38:10,406 --> 01:38:11,908
INFORMATION TO ADVANCE

2661
01:38:11,908 --> 01:38:14,177
TREATMENTS OUTCOMES DIAGNOSIS

2662
01:38:14,177 --> 01:38:15,311
AND MAINTAIN HISTORICAL

2663
01:38:15,311 --> 01:38:16,446
COLLECTIONS INCLUDING RARE BOOK

2664
01:38:16,446 --> 01:38:22,585
ANDS YOWRNALS. 

2665
01:38:22,585 --> 01:38:23,486
NEXT SLIDE, PLEASE.

2666
01:38:23,486 --> 01:38:27,156
SO THE EXPERTISE THAT NLM HOLDS

2667
01:38:27,156 --> 01:38:28,892
SUPPORTS NIH'S EFFORTS TO

2668
01:38:28,892 --> 01:38:29,726
ADVANCE RESEARCH ON WOMEN'S

2669
01:38:29,726 --> 01:38:31,661
HEALTH AND I WOULD LIKE TO SERE

2670
01:38:31,661 --> 01:38:33,630
SPECIFIC EXAMPLES OF THE ROBUST

2671
01:38:33,630 --> 01:38:35,031
COLLECTIONS WE HAVE THAT WE

2672
01:38:35,031 --> 01:38:35,498
MAINTAIN.

2673
01:38:35,498 --> 01:38:36,766
THE GROUND BREAKING RESEARCH

2674
01:38:36,766 --> 01:38:38,601
INITIATED AS WELL AS THE

2675
01:38:38,601 --> 01:38:41,004
RESEARCH PROJECTS WE FUNDED IN

2676
01:38:41,004 --> 01:38:46,142
SUPPORT OF WOMEN'S HEALTH.

2677
01:38:46,142 --> 01:38:47,877
NEXT SLIDE.

2678
01:38:47,877 --> 01:38:50,113
NLM'S GLOBALLY APPRECIATED

2679
01:38:50,113 --> 01:38:53,082
COLLECTIONS SPANS 11 CENTURIES,

2680
01:38:53,082 --> 01:38:55,151
AND ORIGINATES FROM NEARLY EVERY

2681
01:38:55,151 --> 01:38:56,486
PART OF THE FLOAB.

2682
01:38:56,486 --> 01:38:57,587
WITHIN IT ARE A VARIETY OF

2683
01:38:57,587 --> 01:38:59,622
SOURCES ABOUT THE HISTORY OF

2684
01:38:59,622 --> 01:39:01,724
WOMEN'S HEALTH FROM ARCHIVEAT

2685
01:39:01,724 --> 01:39:02,558
COLLECTIONS OF MANUSCRIPTS,

2686
01:39:02,558 --> 01:39:03,960
PHOTOGRAPHS AND FILMS TO RARE

2687
01:39:03,960 --> 01:39:09,999
AND UNIQUE BOOKS, AS WELL AS

2688
01:39:09,999 --> 01:39:14,537
JOURNALS PASMMENTS AND EFEMRA.

2689
01:39:14,537 --> 01:39:15,605
NEXT SLIDE.

2690
01:39:15,605 --> 01:39:17,640
THE NLM DIGITAL COLLECTIONS

2691
01:39:17,640 --> 01:39:19,175
CONTAIN A FRACTION OF VAST

2692
01:39:19,175 --> 01:39:20,310
COLLECTION ON TOPICS SUCH AS

2693
01:39:20,310 --> 01:39:21,411
WOMEN'S HEALTH.

2694
01:39:21,411 --> 01:39:23,079
THIS SITE INCLUDES A SEARCH BAR

2695
01:39:23,079 --> 01:39:24,280
WHERE YOU ENTER KEY WORDS AND

2696
01:39:24,280 --> 01:39:26,516
GET BACK A HEALTH OF INFORMATION

2697
01:39:26,516 --> 01:39:28,718
INCLUDING JOURNALS, PHOTOGRAPHS

2698
01:39:28,718 --> 01:39:32,422
AND HISTORICAL BROCHURES. 

2699
01:39:32,422 --> 01:39:38,294
FOR EXAMPLE, A SEARCH FOR FEMALE

2700
01:39:38,294 --> 01:39:42,966
SCIENTISTS BOOK CALLED WOMEN'S

2701
01:39:42,966 --> 01:39:45,101
PHYSICAL FREEDOM AND AUTHOR

2702
01:39:45,101 --> 01:39:45,868
PROMOTED SCIENTIFICALLY FOUND

2703
01:39:45,868 --> 01:39:47,003
IDEAS AND TREEPTS FOR

2704
01:39:47,003 --> 01:39:47,770
DISABILITIES THAT AFFECTED WOMEN

2705
01:39:47,770 --> 01:39:50,473
AND IN EARLIER THIS YEAR, TO

2706
01:39:50,473 --> 01:39:53,409
MARK WOMEN'S HEALTHRY MONTH NLM

2707
01:39:53,409 --> 01:39:55,278
POPULAR BLOG CALLED CIRCULATING

2708
01:39:55,278 --> 01:39:56,779
NOW, PUBLISHED A POST THAT

2709
01:39:56,779 --> 01:39:58,748
INVITED READERS TO VIRTUALLY

2710
01:39:58,748 --> 01:39:59,749
TOUR ORIGINAL COLLECTIONS

2711
01:39:59,749 --> 01:40:01,617
SPECIFICALLY THOSE ABOUT WOMEN'S

2712
01:40:01,617 --> 01:40:03,386
HEALTH HISTORY, THE TOUR WALKS

2713
01:40:03,386 --> 01:40:05,388
YOU THROUGH THE HISTORY OF HOW

2714
01:40:05,388 --> 01:40:06,956
WOMEN HAVE EXPERIENCED HEALTH

2715
01:40:06,956 --> 01:40:08,424
AND ILLNESS AND, PRACTICED

2716
01:40:08,424 --> 01:40:09,959
MEDICINE AND WELL AS ADVOCATED

2717
01:40:09,959 --> 01:40:11,361
FOR THE HEALTH AND HEALTH OF

2718
01:40:11,361 --> 01:40:12,662
THEIR FAMILIES SO WE INVITE TO

2719
01:40:12,662 --> 01:40:14,397
YOU REALLY CHECK OUT THESE

2720
01:40:14,397 --> 01:40:16,232
RESOURCES AND ALSO SUBSCRIBE TO

2721
01:40:16,232 --> 01:40:17,967
OUR BLOG, TO RECEIVE WEEKLY

2722
01:40:17,967 --> 01:40:20,169
POSTS OF A VARIETY OF DISCIPLINE

2723
01:40:20,169 --> 01:40:23,773
WRITTEN BY RESEARCHERS WHO HAVE

2724
01:40:23,773 --> 01:40:26,242
PERSONALLY STUDIED AND ACCESSED

2725
01:40:26,242 --> 01:40:30,179
THE NLM COLLECTIONS. 

2726
01:40:30,179 --> 01:40:30,947
NEXT SLIDE, PLEASE.

2727
01:40:30,947 --> 01:40:33,249
AND HERE'S A SAMPLE OF WHAT YOU

2728
01:40:33,249 --> 01:40:36,085
WILL FIND IN OUR COLLECTIONS, OF

2729
01:40:36,085 --> 01:40:40,256
THE MATERIALS ARE CURATED, AND

2730
01:40:40,256 --> 01:40:44,293
THE 1S IN THIS POST DOCUMENT

2731
01:40:44,293 --> 01:40:45,695
HAVE EXPERIENCED HOW WOMEN

2732
01:40:45,695 --> 01:40:47,196
EXPERIENCE HEALTH AND MEDICINE,

2733
01:40:47,196 --> 01:40:48,664
PRACTICE MEDICINE, AND ADVOCATE

2734
01:40:48,664 --> 01:40:50,633
FOR THEIR HEALTH AND THEIR

2735
01:40:50,633 --> 01:40:50,967
FAMILIES.

2736
01:40:50,967 --> 01:40:53,336
IN THEIR RESEARCH THEY DOCUMENT

2737
01:40:53,336 --> 01:40:55,304
SCIENCE BY WOMENS AND PUBLIC

2738
01:40:55,304 --> 01:40:57,140
HELT AND DEBATES ON DECISIONS

2739
01:40:57,140 --> 01:40:59,442
AFFECTING WOMEN AND THEY ALSO

2740
01:40:59,442 --> 01:41:01,377
REVEAL STORIES ABOUT THE

2741
01:41:01,377 --> 01:41:02,345
PERSONAL RESPONSIBILITY AND

2742
01:41:02,345 --> 01:41:02,912
INDIVIDUAL PUBLIC HEALTH.

2743
01:41:02,912 --> 01:41:05,281
IF YOU'RE LOOKING FOR A MORE

2744
01:41:05,281 --> 01:41:08,384
GUIDED TOUR THROUGH THE ANNALS

2745
01:41:08,384 --> 01:41:10,453
OF WOMEN'S HISTORY WE HAVE

2746
01:41:10,453 --> 01:41:11,954
SEVERAL ONLINE EXHIBITS THAT

2747
01:41:11,954 --> 01:41:13,222
DISCUSS WOMEN AND WOMEN'S HEALTH

2748
01:41:13,222 --> 01:41:15,191
IN A VARIETY OF HISTORICAL

2749
01:41:15,191 --> 01:41:16,726
CONTEXT, SOME OF OUR EXHIBITS

2750
01:41:16,726 --> 01:41:18,728
INCLUDE THE VOICES OF ACTIVIST

2751
01:41:18,728 --> 01:41:19,662
EXPTION REFORMERS IN THE U.S.

2752
01:41:19,662 --> 01:41:21,731
WHO HAVE LONG RECOGNIZED THE

2753
01:41:21,731 --> 01:41:23,032
HARM OF DOMESTIC VIOLENCE AND

2754
01:41:23,032 --> 01:41:23,966
THOUGHT TO IMPROVE LIVES OF

2755
01:41:23,966 --> 01:41:27,503
WOMEN IN THOSE ENVIRONMENTS AND

2756
01:41:27,503 --> 01:41:29,572
A UNIQUE NURSING POST CARD

2757
01:41:29,572 --> 01:41:32,542
COLLECTION THAT IS LITERALLY

2758
01:41:32,542 --> 01:41:33,910
ILLUSTRATED AND SHOWS HOW

2759
01:41:33,910 --> 01:41:35,878
NURSING WAS SCENE IN THE 20th

2760
01:41:35,878 --> 01:41:44,220
CENTURY SOCIETY IN CULTURE.

2761
01:41:44,220 --> 01:41:47,623
OUR NEWEST EXHIBIT CALLED RISE,

2762
01:41:47,623 --> 01:41:49,559
SERVE AND LEAD, INCLUDES

2763
01:41:49,559 --> 01:41:51,661
MENTORSHIP AND ACTION MADE BY

2764
01:41:51,661 --> 01:41:53,729
SELECTION OF WOMEN'S PHYSICIAN

2765
01:41:53,729 --> 01:41:55,798
ORIGINALLY FEATURED IN THE

2766
01:41:55,798 --> 01:41:56,566
CHANGING SPACE.

2767
01:41:56,566 --> 01:41:58,601
YOU WILL SEE HERE MUCH

2768
01:41:58,601 --> 01:42:00,470
INFORMATION ON DR. VIRGINIA

2769
01:42:00,470 --> 01:42:02,538
APGAR FOR THE SCORE THAT BEARS

2770
01:42:02,538 --> 01:42:04,273
HER NAME, AND OTHER NOTABLE

2771
01:42:04,273 --> 01:42:07,777
WOMEN IN SCIENCE SUCH AS

2772
01:42:07,777 --> 01:42:08,711
DR. HELEN OCTAVIA DICKENS, AND

2773
01:42:08,711 --> 01:42:13,549
YOU CAN FIND MORE INFORMATION ON

2774
01:42:13,549 --> 01:42:15,284
THESE PEOPLE -- ON THESE WOMEN

2775
01:42:15,284 --> 01:42:19,188
IN OUR EXHIBITS. 

2776
01:42:19,188 --> 01:42:19,922
NEXT SLIDE, PLEASE.

2777
01:42:19,922 --> 01:42:23,726
SO MOVING ON TO OUR PRODUCTS AND

2778
01:42:23,726 --> 01:42:25,828
SERVICES, THESE ARE THE -- THESE

2779
01:42:25,828 --> 01:42:27,029
PRODUCTS AND SERVICES CONNECT US

2780
01:42:27,029 --> 01:42:29,031
TO ACCURATE TUSTED AND CURRENT

2781
01:42:29,031 --> 01:42:31,534
HEALTH AND RESEARCH INFORMATION,

2782
01:42:31,534 --> 01:42:35,404
NLM MANAGES AND MAINTAINING

2783
01:42:35,404 --> 01:42:37,140
BIOMEDICAL INFORMATION SERVICES

2784
01:42:37,140 --> 01:42:38,741
THEY MAKE BIOMEDICAL DATA AND

2785
01:42:38,741 --> 01:42:40,343
INFORMATION AVAILABLE IN SUPPORT

2786
01:42:40,343 --> 01:42:42,411
OF HEALTH INCLUDING SUPPORT ON

2787
01:42:42,411 --> 01:42:42,979
RESEARCH WOMEN'S HEALTH.

2788
01:42:42,979 --> 01:42:45,014
WE ARE CURRENT LOAMACYY WORKING

2789
01:42:45,014 --> 01:42:47,150
TO UNIFY OUR PLATFORMS AND

2790
01:42:47,150 --> 01:42:49,185
DATABASES TO IMPROVE

2791
01:42:49,185 --> 01:42:52,622
INTERORPERABILITY AND DISCOVERY

2792
01:42:52,622 --> 01:42:53,689
ACROSS MULTIPLE DATA

2793
01:42:53,689 --> 01:42:56,192
REPOSITORIES INCLUDING THOSE

2794
01:42:56,192 --> 01:42:59,462
THAT HOLE INFORMATION ON

2795
01:42:59,462 --> 01:43:01,564
CLENICAL TRIALS, DATA, GENOMICS

2796
01:43:01,564 --> 01:43:01,931
AND MORE.

2797
01:43:01,931 --> 01:43:03,099
THEY COLLECT FEEDBACK AND

2798
01:43:03,099 --> 01:43:05,635
TRANSLATE IT INTO INTUITIVE

2799
01:43:05,635 --> 01:43:06,302
PERSONALIZED BIOMEDICAL

2800
01:43:06,302 --> 01:43:06,903
INFORMATION DISCOVERY AND THE

2801
01:43:06,903 --> 01:43:08,571
BEST PART ABOUT ALL OF OUR

2802
01:43:08,571 --> 01:43:10,773
PRODUCTS AND SERVICES, THEY'RE

2803
01:43:10,773 --> 01:43:11,240
AVAILABLE FOR FREE.

2804
01:43:11,240 --> 01:43:13,442
I WOULD LIKE TO HIGHLIGHT THAT

2805
01:43:13,442 --> 01:43:15,678
EVERY DAY, MILLIONS OF

2806
01:43:15,678 --> 01:43:16,779
SCIENTISTS HELP PROFESSIONALS

2807
01:43:16,779 --> 01:43:18,481
AND MEMBERS OF THE PUBLIC USE

2808
01:43:18,481 --> 01:43:20,917
OUR ONLINE SERVICES TO SUBMIT

2809
01:43:20,917 --> 01:43:21,751
DAT ATRANSLATE RESEARCH, RESULT

2810
01:43:21,751 --> 01:43:25,087
IN A NEW TREATMENT, ACCESS OUR

2811
01:43:25,087 --> 01:43:27,023
COLLECTIONS, DEVELOP NEW

2812
01:43:27,023 --> 01:43:28,791
PRODUCTS, AND INFORM CLINICAL

2813
01:43:28,791 --> 01:43:30,426
DECISION MAKING AND IMPROVE

2814
01:43:30,426 --> 01:43:31,060
HEALTH.

2815
01:43:31,060 --> 01:43:36,866
IN FACT, NLM RECEIVED 10S OF

2816
01:43:36,866 --> 01:43:38,601
TERRA BYTES DATA DAILY

2817
01:43:38,601 --> 01:43:41,037
PROCESSING ON AN AVERAGE OF 2

2818
01:43:41,037 --> 01:43:43,005
PEDABYTES OF DATA PER DAY.

2819
01:43:43,005 --> 01:43:46,542
WE ALSO HAVE 4-10 MILLION USERS

2820
01:43:46,542 --> 01:43:48,077
THAT ACCESS HUNDREDS OF TERRA

2821
01:43:48,077 --> 01:43:50,780
BYTES OF DAILY FROM NLM MANAGED

2822
01:43:50,780 --> 01:43:55,484
ISHT ACTIVE WEBSITES AND

2823
01:43:55,484 --> 01:43:57,253
1000th OF DERRA BYTES ARE

2824
01:43:57,253 --> 01:43:57,853
DOWNLOADED DATAY SOPHISTICATED

2825
01:43:57,853 --> 01:43:59,755
WE'RE IN THE BUSINESS OF PAIKING

2826
01:43:59,755 --> 01:44:02,024
DATA AND INFORMATION AVAILABLE

2827
01:44:02,024 --> 01:44:03,226
AND WE HAVE A LOT OF PEOPLE

2828
01:44:03,226 --> 01:44:05,928
COMING TO OUR SITE.

2829
01:44:05,928 --> 01:44:07,663
OUR PRODUCTS AND SERVICES ARE

2830
01:44:07,663 --> 01:44:08,931
WITHIN THE TOP 3 DEPARTMENT OF

2831
01:44:08,931 --> 01:44:10,800
HEALTH AND HUMAN SERVICES

2832
01:44:10,800 --> 01:44:12,602
WEBSITES THAT ARE ACCESSED DAILY

2833
01:44:12,602 --> 01:44:17,240
BY THE PUBLIC.

2834
01:44:17,240 --> 01:44:18,140
NEXT SLIDE.

2835
01:44:18,140 --> 01:44:19,342
OUR MOST WIDELY USED RESOURCE

2836
01:44:19,342 --> 01:44:20,610
WHICH MANY OF YOU MAY BE

2837
01:44:20,610 --> 01:44:23,646
FAMILIAR WITH IS PUB MED, IT'S A

2838
01:44:23,646 --> 01:44:24,547
SEARCHABLE BIBLIOGRAPHIC

2839
01:44:24,547 --> 01:44:26,249
DATABASE THAT'S AVAILABLE TO

2840
01:44:26,249 --> 01:44:26,916
ANYONE WHETHER RESEARCH,

2841
01:44:26,916 --> 01:44:29,518
CLINICIAN OR MEMBER OF OUR

2842
01:44:29,518 --> 01:44:30,820
COMMUNITY, IT'S AVAILABLE TO

2843
01:44:30,820 --> 01:44:32,688
PUBLIC -- IT'S BEEN AVAILABLE TO

2844
01:44:32,688 --> 01:44:36,092
THE PUBLIC SINCE 1996, AND IT

2845
01:44:36,092 --> 01:44:37,727
CONTAINS MORE THAN 37 MILLION

2846
01:44:37,727 --> 01:44:39,328
CITATIONS AND ABSTRACTS OF

2847
01:44:39,328 --> 01:44:42,698
BIOMEDICAL AND LIFE SCANSES

2848
01:44:42,698 --> 01:44:44,166
LITERATURE, THAT SUPPORT

2849
01:44:44,166 --> 01:44:45,368
RESEARCH INCLUDING THE LATEST

2850
01:44:45,368 --> 01:44:47,403
BIOMEDICAL RESEARCH AND STUDIES

2851
01:44:47,403 --> 01:44:49,238
FOCUSED ON WOMEN'S HEALTH.

2852
01:44:49,238 --> 01:44:51,307
PUB MED, MAKE ITS SIMPLE TO FIND

2853
01:44:51,307 --> 01:44:54,043
HIGH QUALITY RESEARCH ON TOPICS

2854
01:44:54,043 --> 01:44:56,045
SUCH AS REPRODUCTIVE HEALTH,

2855
01:44:56,045 --> 01:44:57,213
PREGNANCY, MENOPAUSE AND CANCERS

2856
01:44:57,213 --> 01:44:58,614
AND USES FILTERS AND SEARCH

2857
01:44:58,614 --> 01:45:00,683
TOOLS TO 0 IN ON WHAT MATTERS

2858
01:45:00,683 --> 01:45:02,752
MOST TO THE USER.

2859
01:45:02,752 --> 01:45:06,222
AND BY SUPPORTING ACCESS TO A

2860
01:45:06,222 --> 01:45:07,690
DIVERSE AND UPTO DATE

2861
01:45:07,690 --> 01:45:09,859
INFORMATION PUB MED HELPS

2862
01:45:09,859 --> 01:45:11,127
ADVANCE RESEARCH, GUIDE CLINICAL

2863
01:45:11,127 --> 01:45:13,629
CARE AND INFORM POLICY TO HELP

2864
01:45:13,629 --> 01:45:16,899
IMPROVE THE OUTCOMES OF WOMEN.

2865
01:45:16,899 --> 01:45:19,735
MED LINE PLUS IS A PORTAL THAT

2866
01:45:19,735 --> 01:45:21,437
PROVIDES HIGH QUALITY RELEVANT

2867
01:45:21,437 --> 01:45:23,139
CONSUMER HELT AND WELLNESS

2868
01:45:23,139 --> 01:45:24,874
INFORMATION TO THE PUBLIC.

2869
01:45:24,874 --> 01:45:26,609
AND THIS SERVICE OFFERS HEALTH

2870
01:45:26,609 --> 01:45:29,879
INFORMATION THAT'S EASY TO READ,

2871
01:45:29,879 --> 01:45:31,714
AND UNDERSTAND IN BOTH ENGLISH

2872
01:45:31,714 --> 01:45:33,549
AND SPANISH MAKING THE LATEST

2873
01:45:33,549 --> 01:45:35,318
INFO AND HEALTH ON WELLNESS

2874
01:45:35,318 --> 01:45:37,253
SUCCESSFUL TO EVERYTHING, IT

2875
01:45:37,253 --> 01:45:39,755
COVERS SPECIFIC HEALTH TOPICS

2876
01:45:39,755 --> 01:45:41,991
AND WOMEN'S HEALTH, INCLUDING

2877
01:45:41,991 --> 01:45:43,592
PREGNANCY, HEALTH SCREENINGS,

2878
01:45:43,592 --> 01:45:44,994
HUMAN GENETICS AND ANATOMY,

2879
01:45:44,994 --> 01:45:46,495
MEDICAL TESTS AND MEDICATIONS.

2880
01:45:46,495 --> 01:45:47,863
AND WHILE SOME OF THE

2881
01:45:47,863 --> 01:45:49,732
INFORMATION IS PRODUCED BY NLM,

2882
01:45:49,732 --> 01:45:53,369
WE ALSO PROVIDE CURATED LINKS TO

2883
01:45:53,369 --> 01:45:54,437
OTHER AUTHORITATIVE HEALTH

2884
01:45:54,437 --> 01:46:00,643
INFORMATION  INCLUDING OTHER NIH

2885
01:46:00,643 --> 01:46:01,811
INSTITUTES, WEBSITESES ARE,

2886
01:46:01,811 --> 01:46:04,146
GOVERNMENT AGENCIES AS WELL AS

2887
01:46:04,146 --> 01:46:05,181
REVIEWED AND NONEMBEDDED

2888
01:46:05,181 --> 01:46:05,948
RESOURCES.

2889
01:46:05,948 --> 01:46:07,750
BUT THE PROVE OF NLM IS THE

2890
01:46:07,750 --> 01:46:09,685
IMPACT IN NUMBERS MUCH IT'S 1 OF

2891
01:46:09,685 --> 01:46:12,555
THE MOST VISITED U.S. GOVERNMENT

2892
01:46:12,555 --> 01:46:14,256
WEBSITES WITH OVER 400 MILLION

2893
01:46:14,256 --> 01:46:16,092
USERS LANDING  ON THESE WEBPAGES

2894
01:46:16,092 --> 01:46:17,259
EACH YEAR.

2895
01:46:17,259 --> 01:46:19,762
PUB MED CENTRAL ON THE OTHER

2896
01:46:19,762 --> 01:46:22,531
HAND, IS NLM'S FULL TEXT ARCHIVE

2897
01:46:22,531 --> 01:46:24,800
OF BIOMEDICAL JOURNAL LITERATURE

2898
01:46:24,800 --> 01:46:26,635
AND INCLUDES OVER 7 AND HALF

2899
01:46:26,635 --> 01:46:27,937
MILLION FULL TEXT ARTICLES, MOST

2900
01:46:27,937 --> 01:46:29,805
OF THE CONTENT COMES FROM

2901
01:46:29,805 --> 01:46:31,874
JOURNALS OR PUBLISHERS THAT HAVE

2902
01:46:31,874 --> 01:46:34,143
AGREED TO DEPOSIT THE ARTICLES

2903
01:46:34,143 --> 01:46:36,345
THEY PUBLISH IN PMC AND IN FACT

2904
01:46:36,345 --> 01:46:39,815
OVER 25,000 JOURNALS CURRENTLY

2905
01:46:39,815 --> 01:46:43,319
DEPOSIT THEIR ENTIRE CONTENT IN

2906
01:46:43,319 --> 01:46:44,620
PMC, WE'VE ADDED ANOTHER MILLION

2907
01:46:44,620 --> 01:46:47,256
ARTICLES THROUGH OUR

2908
01:46:47,256 --> 01:46:48,657
DIGITIZATION PROJECTS, AND PMC

2909
01:46:48,657 --> 01:46:50,426
ALSO SUPPORTS THE NIH PUBLIC

2910
01:46:50,426 --> 01:46:52,928
ACCESS POLICY AS WELL AS THE

2911
01:46:52,928 --> 01:47:01,036
SHARING OF ARTICLES FROM OTHER

2912
01:47:01,036 --> 01:47:03,205
FEDERAL PARTNERS.

2913
01:47:03,205 --> 01:47:03,506
NEXT SLIDE.

2914
01:47:03,506 --> 01:47:04,373
CLINICALTRIALS.GOV IS THE PLACE

2915
01:47:04,373 --> 01:47:06,475
TO GO TO FIND INFORMATION ABOUT

2916
01:47:06,475 --> 01:47:07,977
ONGOING AND COMPLETED CLIBICAL

2917
01:47:07,977 --> 01:47:10,212
TRIALS INCLUDING MANY ON

2918
01:47:10,212 --> 01:47:10,846
PREGNANCY, CONTRACEPTION, BREAST

2919
01:47:10,846 --> 01:47:12,448
CANCER AND OTHER WOMEN'S HEALTH

2920
01:47:12,448 --> 01:47:13,616
CONDITIONS, IT LETS YOU EASILY

2921
01:47:13,616 --> 01:47:16,685
SEARCH FOR STUDIES TO SEE WHAT'S

2922
01:47:16,685 --> 01:47:20,022
NEW, AS FAR AS TREATMENTS AND

2923
01:47:20,022 --> 01:47:21,490
INTERVENTIONS ARE CONCERNED OR

2924
01:47:21,490 --> 01:47:22,758
EVEN FIND OPPORTUNITIES TO

2925
01:47:22,758 --> 01:47:25,227
PARTICIPATE IN CLINICAL TRIALS.

2926
01:47:25,227 --> 01:47:27,062
BAY MAKING THE INFORMATION

2927
01:47:27,062 --> 01:47:28,697
WIDELY AVAILABLE, WE HAVE HELP

2928
01:47:28,697 --> 01:47:31,200
PROMOTE TRANSPARENCY OF CLINICAL

2929
01:47:31,200 --> 01:47:32,001
RESEARCH, SUPPORT EVIDENCE BASED

2930
01:47:32,001 --> 01:47:33,736
CARE AND ALSO ADVANCE RESEARCH

2931
01:47:33,736 --> 01:47:35,738
THAT CAN LEAD TO BETTER HEALTH,

2932
01:47:35,738 --> 01:47:41,076
HEALTH OUTCOMES FOR ALL.

2933
01:47:41,076 --> 01:47:43,512
NIN 2017 NEW REGULATIONS WERE

2934
01:47:43,512 --> 01:47:44,613
RELEASED THAT REQUIRED MOST

2935
01:47:44,613 --> 01:47:47,616
CLINICAL TRIALS OF FDA REGULATED

2936
01:47:47,616 --> 01:47:49,351
DRUGS BIOLOGICS OR DEVIETIONS IN

2937
01:47:49,351 --> 01:47:50,686
ALL CLINICAL TRIALS FUNDED BY

2938
01:47:50,686 --> 01:47:57,426
NIH TO BE REGISTER INDEED THE

2939
01:47:57,426 --> 01:47:58,093
DATABASE.

2940
01:47:58,093 --> 01:48:02,198
AND THESE REGULATIONS REQUIRE

2941
01:48:02,198 --> 01:48:05,134
DEPOSITORS TO LEAVE THE

2942
01:48:05,134 --> 01:48:07,336
PUBLICATIONS IN THIS, BUT HAVING

2943
01:48:07,336 --> 01:48:08,504
THE REGISTRY PUBLICLY AVAILABLE

2944
01:48:08,504 --> 01:48:10,105
CAN INFORM OTHER FUTURE RESEARCH

2945
01:48:10,105 --> 01:48:12,274
AND FUNDING DECISIONS TO HELP

2946
01:48:12,274 --> 01:48:14,243
IMPROVE THE RESEARCH ECOSYSTEM

2947
01:48:14,243 --> 01:48:17,079
SUCH AS BY REDUCING TRIAL

2948
01:48:17,079 --> 01:48:18,380
DUPLICATION AND UNSAFE OR

2949
01:48:18,380 --> 01:48:22,218
INEFFECT -IVE ISHT VENTIONS,

2950
01:48:22,218 --> 01:48:23,652
MEET ETHICAL OBLIGATIONS TO

2951
01:48:23,652 --> 01:48:29,992
HUMAN TAR  PARTICIPANTS IN RESE.

2952
01:48:29,992 --> 01:48:33,729
AND IN THE PAST SEVERAL YEARS

2953
01:48:33,729 --> 01:48:35,931
WHICH YOU'VE HEARD DR. CLAYTON

2954
01:48:35,931 --> 01:48:37,900
MENTION, WE'VE ALSO ADOPTED

2955
01:48:37,900 --> 01:48:39,401
CLINICAL TRIALS .GOV TO MEET THE

2956
01:48:39,401 --> 01:48:44,373
NEEDS OF OUR COMMUNITY. 

2957
01:48:44,373 --> 01:48:45,608
NEXT SLIDE, PLEASE.

2958
01:48:45,608 --> 01:48:48,677
ANOTHER AREA UNDER NLM'S PURVIEW

2959
01:48:48,677 --> 01:48:55,851
IS MAINTAINING AND STANDARDIZING

2960
01:48:55,851 --> 01:48:56,519
THESE.

2961
01:48:56,519 --> 01:48:58,087
THESE STAND AWRPDS INSURE THAT

2962
01:48:58,087 --> 01:48:58,687
RESEARCH IS ACCURATE, CONSIST

2963
01:48:58,687 --> 01:49:00,556
AND THEN THE CAN BE COMBINED

2964
01:49:00,556 --> 01:49:03,025
ACROSS STUDIES MAKING IT EASIER

2965
01:49:03,025 --> 01:49:06,562
TO IDENTIFY TRENDS AND GAPS.

2966
01:49:06,562 --> 01:49:08,898
NLM ALSO DEVELOPS, MAINTAINS,

2967
01:49:08,898 --> 01:49:10,132
PRODUCES OR DISTRIBUTES OTHER

2968
01:49:10,132 --> 01:49:11,634
MEDICAL TERMINOLOGIES THAT ARE

2969
01:49:11,634 --> 01:49:13,269
USED FOR CLINICAL OR RESEARCH

2970
01:49:13,269 --> 01:49:17,907
PURPOSES AND THESE TERMINOLOGIES

2971
01:49:17,907 --> 01:49:19,775
DISAMBUTIGATE DRUG NAMES,

2972
01:49:19,775 --> 01:49:21,377
IDENTIFIED PROCEDURES FOR EHRs

2973
01:49:21,377 --> 01:49:23,846
AND MUCH MORE, THE STANDARDS

2974
01:49:23,846 --> 01:49:25,214
INSURE THAT INFORMATION ABOUT

2975
01:49:25,214 --> 01:49:27,016
HEALTH, SUCH AS DIAGNOSIS,

2976
01:49:27,016 --> 01:49:29,985
TREATMENTS AND OUTCOMES, CAN BE

2977
01:49:29,985 --> 01:49:32,154
ACCURATELY RECORDED, SHARED AND

2978
01:49:32,154 --> 01:49:34,189
ANALYZED ACROSS DIFFERENT

2979
01:49:34,189 --> 01:49:35,324
STUDIES AND SETTINGS.

2980
01:49:35,324 --> 01:49:37,259
SO BY ENABLING RELIABLE AND

2981
01:49:37,259 --> 01:49:38,561
COMPARABLE DATA WE HELP

2982
01:49:38,561 --> 01:49:39,995
RESEARCHERS AND CLINICIANS WORK

2983
01:49:39,995 --> 01:49:42,064
TOGETHER, MORE EFFECTIVELY, TO

2984
01:49:42,064 --> 01:49:43,666
IMPROVE HEALTH OUTCOMES,

2985
01:49:43,666 --> 01:49:49,471
INCLUDING THOSE FOR WOMEN.

2986
01:49:49,471 --> 01:49:51,707
NEXT SLIDE.

2987
01:49:51,707 --> 01:49:54,176
NLM OFTEN MANAGES SEVERAL

2988
01:49:54,176 --> 01:49:55,911
MOLECULAR BIOREPOSITORY FOR

2989
01:49:55,911 --> 01:49:57,313
ASSOCIATED METADATA GENERATED BY

2990
01:49:57,313 --> 01:49:58,981
RESEARCHERS PUBLIC HEALTH LABS,

2991
01:49:58,981 --> 01:49:59,915
SEQUENCING CENTERS AND OTHERS.

2992
01:49:59,915 --> 01:50:03,852
MANY OF THESE YOU PROBABLY HAVE

2993
01:50:03,852 --> 01:50:04,887
HEARD ABOUT, AND THESE

2994
01:50:04,887 --> 01:50:06,755
REPOSITORY STORE, PRESERVE AND

2995
01:50:06,755 --> 01:50:08,257
ORGANIZE DATA FOR SUBMITTERS,

2996
01:50:08,257 --> 01:50:11,560
AND THOSE WHO REUSE THE DATA FOR

2997
01:50:11,560 --> 01:50:12,962
ADDITIONAL ANALYSIS AND

2998
01:50:12,962 --> 01:50:14,530
RESEARCH, AS WELL AS CARRY OUT

2999
01:50:14,530 --> 01:50:16,632
ADDITIONAL TYPES OF ANALYSIS TO

3000
01:50:16,632 --> 01:50:18,834
ADD VALUE TO DAT THAT HAVE

3001
01:50:18,834 --> 01:50:22,471
ALREADY BEEN SUBMITTED.

3002
01:50:22,471 --> 01:50:23,372
THESE REPOSITORY PROVIDE

3003
01:50:23,372 --> 01:50:25,040
SERVICES THAT ENABLE RESEARCHERS

3004
01:50:25,040 --> 01:50:27,209
AND OTHERS TO ANALYZE, ACCESS,

3005
01:50:27,209 --> 01:50:29,411
SEARCH, VIEW AND DOWNLOAD THE

3006
01:50:29,411 --> 01:50:29,745
DATA.

3007
01:50:29,745 --> 01:50:31,580
FOR EXAMPLE, SEQUENCE DATA IS

3008
01:50:31,580 --> 01:50:33,849
MORE REUSABLE WHEN RESEARCHER

3009
01:50:33,849 --> 01:50:36,218
HAS ADDITIONAL METADATA SUCH AS

3010
01:50:36,218 --> 01:50:38,253
INFORMATION ABOUT TD SOURCE, THE

3011
01:50:38,253 --> 01:50:39,321
NAME OF THE ORGANISM AND THE

3012
01:50:39,321 --> 01:50:43,626
NAME OF THE LOCATION WHERE THE

3013
01:50:43,626 --> 01:50:44,727
ORGANISM WAS COLLECTED.

3014
01:50:44,727 --> 01:50:45,160
NEXT SLIDE, PLEASE.

3015
01:50:45,160 --> 01:50:47,696
AND SOME OF THESE REPOSITORIES

3016
01:50:47,696 --> 01:50:49,832
ARE COLLECTING AND MAINTAINING

3017
01:50:49,832 --> 01:50:50,399
GENETIC SEQUENCE INFORMATION

3018
01:50:50,399 --> 01:50:52,601
THAT CAN BE USED TO

3019
01:50:52,601 --> 01:50:53,636
SIGNIFICANTLY IMPACT BY O

3020
01:50:53,636 --> 01:50:54,937
MEDICAL RESEARCH AND ARE BROADER

3021
01:50:54,937 --> 01:50:59,642
UNDERSTANDING OF THE WORLD

3022
01:50:59,642 --> 01:51:00,809
AROUND US, SEQUENCE DATA SUCH AS

3023
01:51:00,809 --> 01:51:02,778
THIS ARE BEING USED TO

3024
01:51:02,778 --> 01:51:05,347
ILLUMINATE THE STUDY OF

3025
01:51:05,347 --> 01:51:06,849
ECOSYSTEMS, POPULATIONS,

3026
01:51:06,849 --> 01:51:08,017
BIODIVERSITY AND PUBLIC HEALTH

3027
01:51:08,017 --> 01:51:09,852
THROUGH UNDERSTANDING TENOAMS,

3028
01:51:09,852 --> 01:51:11,487
GENES, TRANSCRIPTS AND PROTEINS.

3029
01:51:11,487 --> 01:51:13,789
AND AS SUCH THE TYPE OF DATA

3030
01:51:13,789 --> 01:51:16,959
HOUSED IN THESE REPOSITORIES

3031
01:51:16,959 --> 01:51:21,163
INCLUDE DNA, RNA AND PROTEINS.

3032
01:51:21,163 --> 01:51:21,830
NEXT SLIDE.

3033
01:51:21,830 --> 01:51:24,066
MANY OF YOU HAVE PROBABLY HEARD

3034
01:51:24,066 --> 01:51:26,035
ABOUT GEN BANK AND THE SEQUENCE

3035
01:51:26,035 --> 01:51:27,536
READ ARCHIVE.

3036
01:51:27,536 --> 01:51:31,974
GENBANK IS THE NIH SEQUENCE

3037
01:51:31,974 --> 01:51:35,010
REPOSITORY THAT PROVIDES,

3038
01:51:35,010 --> 01:51:37,279
COLLECT FOR ALL DOMAINS OF LIFE.

3039
01:51:37,279 --> 01:51:38,881
IT PROVIDES ACCESS TO THE MOST

3040
01:51:38,881 --> 01:51:40,616
UPTO DATE AND COMPREHENSIVE

3041
01:51:40,616 --> 01:51:42,017
SEQUENCE INFORMATION THAT'S

3042
01:51:42,017 --> 01:51:44,520
ANALYZED CURATED AND ASSEMBLED

3043
01:51:44,520 --> 01:51:46,889
INTO LONGER MOLECULES, FOR MORE

3044
01:51:46,889 --> 01:51:50,726
THAN 4.75 BILLION SEQUENCE

3045
01:51:50,726 --> 01:51:52,461
RECORDS AND OVER 228 TERRA BYTES

3046
01:51:52,461 --> 01:51:55,431
OF DATA.

3047
01:51:55,431 --> 01:51:56,865
BY CONTRAST, SRACONTAINS THE RAW

3048
01:51:56,865 --> 01:52:00,736
DATA, DATA THAT HAS NOT BEEN

3049
01:52:00,736 --> 01:52:02,471
ANALYZED, CURATED OR ASSEMBLED

3050
01:52:02,471 --> 01:52:03,539
INTO LONGER MOLECULES AND ACCESS

3051
01:52:03,539 --> 01:52:08,410
TO THE DAILY BASIS THEA IN THESE

3052
01:52:08,410 --> 01:52:09,912
REPOSITORIES FOR EXAMPLE CAN

3053
01:52:09,912 --> 01:52:10,879
HELP TO FACILITATE THE

3054
01:52:10,879 --> 01:52:12,748
DEVELOPMENT OF NOVEL AND DATA

3055
01:52:12,748 --> 01:52:14,049
SCIENCE METHODS INCLUDING AI TO

3056
01:52:14,049 --> 01:52:16,218
SUPPORT DATA SHARING AND

3057
01:52:16,218 --> 01:52:16,919
REPRODUCE ABILITY RESEARCH AND

3058
01:52:16,919 --> 01:52:18,087
ALSO HELP TO URGT IFER

3059
01:52:18,087 --> 01:52:27,696
UNDERSTAND THE HEALTH OF WOMEN.

3060
01:52:27,696 --> 01:52:28,363
NEXT SLIDE, PLEASE.

3061
01:52:28,363 --> 01:52:31,934
SO THROUGH THESE PROGRAMS, NLM

3062
01:52:31,934 --> 01:52:34,002
LAYS A CRITICAL ROLE IN

3063
01:52:34,002 --> 01:52:36,171
ADVANCING DATA SCIENCE AND

3064
01:52:36,171 --> 01:52:37,940
BIO-INFORMATICS RESEARCH FOR THE

3065
01:52:37,940 --> 01:52:38,707
BENEFITS OF UNDERSTANDING

3066
01:52:38,707 --> 01:52:41,510
RESEARCH AND HEALTH. 

3067
01:52:41,510 --> 01:52:43,312
IN ACCIDENT SLIDE.

3068
01:52:43,312 --> 01:52:44,513
NLM'S INVESTIGATORS ARE

3069
01:52:44,513 --> 01:52:46,548
CONDUCTING NOVEL RESEARCH IN OUR

3070
01:52:46,548 --> 01:52:48,283
DIVISION OF INTRAMURAL RESEARCH.

3071
01:52:48,283 --> 01:52:49,618
OUR DIVISION OF INTRAMURAL

3072
01:52:49,618 --> 01:52:52,688
RESEARCH IS MADE UP OF TALENTED

3073
01:52:52,688 --> 01:52:54,723
RESEARCHERS WHO DEVELOP AND

3074
01:52:54,723 --> 01:52:55,591
APPLY COMPUTATIONAL APPROACHES

3075
01:52:55,591 --> 01:52:59,428
TO A BROAD RANGE OF INFORMATION

3076
01:52:59,428 --> 01:53:00,462
PROBLEMS AND BIOLOGY,

3077
01:53:00,462 --> 01:53:01,764
BIOMEDICINE AND HUMAN HEALTH

3078
01:53:01,764 --> 01:53:04,967
INCLUDING THOSE THAT DIRECTLY

3079
01:53:04,967 --> 01:53:05,434
IMPACT WOMEN'S HEALTH.

3080
01:53:05,434 --> 01:53:07,169
OUR INTRA MIEWR WILLA RESEARCH

3081
01:53:07,169 --> 01:53:10,472
HAS A COMPARATIVE ADVANCAGE IN

3082
01:53:10,472 --> 01:53:12,474
IMPLIED WORK AND AIMED AT

3083
01:53:12,474 --> 01:53:13,242
IMPROVING HUMAN HEALTH AROUND

3084
01:53:13,242 --> 01:53:14,810
THE WORLD.

3085
01:53:14,810 --> 01:53:15,811
IT ALSO PROVIDES CRUCIAL

3086
01:53:15,811 --> 01:53:17,079
TRAINING AND RESEARCH

3087
01:53:17,079 --> 01:53:18,046
OPPORTUNITIES FOR OPPORTUNITIES

3088
01:53:18,046 --> 01:53:20,215
AND TRAINEES SETTING THE STAGE

3089
01:53:20,215 --> 01:53:22,084
FOR THE SUCCESS OF THE NEXT

3090
01:53:22,084 --> 01:53:22,851
GENERATION OF RESEARCHERS.

3091
01:53:22,851 --> 01:53:24,620
AND IN THE NEXT 2 SLIDES I JUST

3092
01:53:24,620 --> 01:53:28,056
WANT TO GIVE A FEW EXAMPLES OF

3093
01:53:28,056 --> 01:53:33,796
WHAT NLM'S RESEARCHERS DO.

3094
01:53:33,796 --> 01:53:34,797
NEXT SLIDE.

3095
01:53:34,797 --> 01:53:38,433
SO THE FIRST EXAMPLE IS A YEAR'S

3096
01:53:38,433 --> 01:53:39,568
LONG COLLABORATION WITH

3097
01:53:39,568 --> 01:53:41,870
COUNTERPARTS AT THE NATIONAL

3098
01:53:41,870 --> 01:53:43,739
CANCER INSTITUTE TO RELIABLY

3099
01:53:43,739 --> 01:53:45,874
DETECT CERVICAL CANCER IN WOMEN

3100
01:53:45,874 --> 01:53:47,743
LIVING WITH AND WITHOUT HIV

3101
01:53:47,743 --> 01:53:51,480
USING AI AND MEDICAL IMAGING.

3102
01:53:51,480 --> 01:53:53,849
THE RESEARCH INCLUDES

3103
01:53:53,849 --> 01:53:55,284
PARTICIPATION OF SEVERALUS

3104
01:53:55,284 --> 01:53:56,251
ACADEMIC INSTIEWGS,

3105
01:53:56,251 --> 01:53:56,952
INTERNATIONAL ORGANIZATIONS,

3106
01:53:56,952 --> 01:54:01,590
CLINICAL CENTERS IN VARIOUS

3107
01:54:01,590 --> 01:54:02,491
COUNTRY AND INDUSTRY.

3108
01:54:02,491 --> 01:54:03,759
AND AN OBSERVATIONAL STUDY OF

3109
01:54:03,759 --> 01:54:05,627
DEEP LEARNING AND AUTOMATED

3110
01:54:05,627 --> 01:54:08,463
EVALUATION OF CERVICAL IMAGES

3111
01:54:08,463 --> 01:54:09,965
FOR CANCER SCREENING, THE

3112
01:54:09,965 --> 01:54:11,600
RESULTS SUGGEST THAT THE METHOD

3113
01:54:11,600 --> 01:54:14,002
OF USING THE IMAGES FROM

3114
01:54:14,002 --> 01:54:15,370
CERVICAL CANCER SCREENINGS TO

3115
01:54:15,370 --> 01:54:19,107
TRAIN LARGE LANGUAGE MODELINGS

3116
01:54:19,107 --> 01:54:20,309
COULD POTENTIALLY HELP CATCH

3117
01:54:20,309 --> 01:54:23,478
CERVICAL CANCER EARLIER AND MORE

3118
01:54:23,478 --> 01:54:27,916
EASILY.

3119
01:54:27,916 --> 01:54:28,483
NEXT SLIDE.

3120
01:54:28,483 --> 01:54:30,319
ANOTHER STUDY FROM A DIFFERENT

3121
01:54:30,319 --> 01:54:32,888
LAB AT NLM, IS WHERE NLM

3122
01:54:32,888 --> 01:54:35,224
RESEARCHERS WERE STUDYING THE

3123
01:54:35,224 --> 01:54:36,625
REGULATORY GENOMICS OF

3124
01:54:36,625 --> 01:54:38,594
POLYCYSTIC OVARIAN SYNDROME

3125
01:54:38,594 --> 01:54:42,164
USING A RESEARCH FRAMEWORK THAT

3126
01:54:42,164 --> 01:54:42,965
INTEGRATES GENOMICS STATISTICAL

3127
01:54:42,965 --> 01:54:44,600
ANALYSIS OF PATIENT DATA AND

3128
01:54:44,600 --> 01:54:46,668
ALSO AI TO UNRAVEL THE MECH

3129
01:54:46,668 --> 01:54:49,471
NICHES AND GENOMIC COMPONENTS

3130
01:54:49,471 --> 01:54:51,773
UNDERLYING PC OS, BY TAILORING

3131
01:54:51,773 --> 01:54:53,375
THEIR WORK TO THIS SPECIFIC

3132
01:54:53,375 --> 01:54:55,611
DISORDER, THE LAB IS LOOKING TO

3133
01:54:55,611 --> 01:54:57,145
IDENTIFY KEY GENETIC VARIANTS

3134
01:54:57,145 --> 01:54:58,647
ASSOCIATE WIDE PC OS, AND THE

3135
01:54:58,647 --> 01:54:59,848
WORK DOES HAVE THE POTENTIA WILL

3136
01:54:59,848 --> 01:55:05,754
TO LAY THE GROUND WORK FOR NOVEL

3137
01:55:05,754 --> 01:55:06,455
DIAGNOSTICS EXPERIMENTAL

3138
01:55:06,455 --> 01:55:09,191
VALIDATION AND DRUG DORPHY TO

3139
01:55:09,191 --> 01:55:13,795
BEST TREAT PC OS.

3140
01:55:13,795 --> 01:55:15,163
NEXT SLIDE.

3141
01:55:15,163 --> 01:55:17,466
NLM RESEARCH FUNDING THROUGH OUR

3142
01:55:17,466 --> 01:55:19,101
DIVISION OF EXTRAMURAL PROGRAMS,

3143
01:55:19,101 --> 01:55:20,502
SUPPORTS HEALTH WERE THAT

3144
01:55:20,502 --> 01:55:22,537
CENTERS ON WOMEN'S UNIQUE HEALTH

3145
01:55:22,537 --> 01:55:25,040
NEEDS PARTICULARLY ON DEVELOPING

3146
01:55:25,040 --> 01:55:26,675
TOOLS AND QUANTITATIVE METHODS

3147
01:55:26,675 --> 01:55:30,946
TO ADDRESS WOMEN'S HEALTH

3148
01:55:30,946 --> 01:55:31,847
ISSUES.

3149
01:55:31,847 --> 01:55:33,448
BY FUNDING INSTRUMENTAL RESEARCH

3150
01:55:33,448 --> 01:55:35,083
NLM CONTRIBUTES TO THE

3151
01:55:35,083 --> 01:55:36,952
ADVANCEMENTS IN BIOMEDICAL AND

3152
01:55:36,952 --> 01:55:38,120
DATA SCIENCE WITH IMPLICATIONS

3153
01:55:38,120 --> 01:55:38,854
THAT IMPROVE HEALTH AND WELL

3154
01:55:38,854 --> 01:55:40,856
BEING AND I WILL LIKE TO SHARE A

3155
01:55:40,856 --> 01:55:43,926
FEW EXAMPLES OF THE TYPE OF

3156
01:55:43,926 --> 01:55:45,260
RESEARCH THAT NLMSUPPORTS

3157
01:55:45,260 --> 01:55:48,096
THROUGH ITS EXTRAMURAL RESEARCH

3158
01:55:48,096 --> 01:55:52,301
PROGRAM.

3159
01:55:52,301 --> 01:55:52,768
NEXT SLIDE.

3160
01:55:52,768 --> 01:55:58,140
SO IN THIS STUDY, PREDICTION OF

3161
01:55:58,140 --> 01:56:01,576
PRETERM BIRTH AND WOMEN, THE

3162
01:56:01,576 --> 01:56:02,978
PROJECT IS FOCUSING ON -- IT'S

3163
01:56:02,978 --> 01:56:06,048
FROM A JOINT PROGRAM WITH THE

3164
01:56:06,048 --> 01:56:07,516
NATIONAL SCIENCE FOUNDATION,

3165
01:56:07,516 --> 01:56:09,918
SMART HEALTH AND BIOMEDICAL

3166
01:56:09,918 --> 01:56:17,526
RESEARCH IN THE ERA OF AI.

3167
01:56:17,526 --> 01:56:18,460
INVESTIGATORS ARE ANALYZING

3168
01:56:18,460 --> 01:56:20,095
MULTIPLE DATA SOURCES TO

3169
01:56:20,095 --> 01:56:21,330
IDENTIFY THE LIKELIHOOD OF

3170
01:56:21,330 --> 01:56:23,332
WHETHER FIRST TIME PREGNANT

3171
01:56:23,332 --> 01:56:24,733
WOMEN WILL EXPERIENCE PRETERM

3172
01:56:24,733 --> 01:56:24,967
BIRTH.

3173
01:56:24,967 --> 01:56:27,069
THE INVESTIGATOR VS ALREADY OOH

3174
01:56:27,069 --> 01:56:28,437
DENTIFIED SEVERAL GENETIC AT

3175
01:56:28,437 --> 01:56:30,973
THAT TIMA ELEMENTS THAT HELP

3176
01:56:30,973 --> 01:56:32,341
PREDICT THESE INDICATIONS AND

3177
01:56:32,341 --> 01:56:33,508
ARE CONTINUING TO EXPLORE THE

3178
01:56:33,508 --> 01:56:35,644
DATA TO FIND ANSWERS TO

3179
01:56:35,644 --> 01:56:39,448
SPONTANEOUS PRETERM BIRTH. 

3180
01:56:39,448 --> 01:56:43,318
NEXT SLIDE, PLEASE. 

3181
01:56:43,318 --> 01:56:44,619
AND ANOTHER STUDY, INVESTIGATORS

3182
01:56:44,619 --> 01:56:47,255
ACKNOWLEDGE THAT WOMEN WITH

3183
01:56:47,255 --> 01:56:49,658
DISABILITIES ARE SIGNIFICANTLY

3184
01:56:49,658 --> 01:56:50,325
UNDERSTUDIED AND UNDERRESOURCED

3185
01:56:50,325 --> 01:56:52,461
GROUP AND SEEKS TO REDUCE HEALTH

3186
01:56:52,461 --> 01:56:52,761
DISPARITIES.

3187
01:56:52,761 --> 01:56:54,696
IN THIS STUDY ON PARTNERING WITH

3188
01:56:54,696 --> 01:56:55,831
WOMEN, WITH DISABILITIES TO

3189
01:56:55,831 --> 01:56:59,267
DEVELOP A HEALTH INFORMATION

3190
01:56:59,267 --> 01:56:59,835
WEBSITE, INVESTIGATORS ARE

3191
01:56:59,835 --> 01:57:01,670
FOCUSED ON CURATING AND

3192
01:57:01,670 --> 01:57:03,171
PROVIDING HEALTH INFORMATION

3193
01:57:03,171 --> 01:57:04,740
THAT'S SPECIFICALLY RELEVANT TO

3194
01:57:04,740 --> 01:57:06,274
WOMEN WITH DISABILITIES WITH THE

3195
01:57:06,274 --> 01:57:07,976
ULTIMATE GOAL OF MEETING THEIR

3196
01:57:07,976 --> 01:57:09,244
HEALTH INFORMATION NEEDS AND

3197
01:57:09,244 --> 01:57:12,214
EMPOWERING THEM AS THEY MANAGE

3198
01:57:12,214 --> 01:57:15,350
THEIR HEALTHCARE.

3199
01:57:15,350 --> 01:57:16,151
NEXT SLIDE.

3200
01:57:16,151 --> 01:57:18,120
AND IN A DIFFERENT STUDY,

3201
01:57:18,120 --> 01:57:20,288
RESEARCHERS ARE EXPLORING THE

3202
01:57:20,288 --> 01:57:22,424
BEST INTERVENTIONS TO ADDRESS

3203
01:57:22,424 --> 01:57:25,494
INTIMATE PARTNER VIOLENCE OR IPV

3204
01:57:25,494 --> 01:57:27,562
AGAINST WOMEN, WHILE GROUP

3205
01:57:27,562 --> 01:57:28,730
THERAPY HAS TRADITIONAL BEEN THE

3206
01:57:28,730 --> 01:57:32,701
STANDARD OF CARE FOR IPVs,

3207
01:57:32,701 --> 01:57:34,269
SOME HAVE EXPERIENCED A

3208
01:57:34,269 --> 01:57:35,570
SIGNATURES 95 KAVENT CHANGE IN

3209
01:57:35,570 --> 01:57:36,838
RESPONSE AND FOR THIS STUDY

3210
01:57:36,838 --> 01:57:38,507
INVESTIGATORS ARE USING A DATA

3211
01:57:38,507 --> 01:57:41,143
DRIVEN APPROACH TO IDENTIFY AND

3212
01:57:41,143 --> 01:57:42,744
TEST AND CUSTOMIZED

3213
01:57:42,744 --> 01:57:44,146
INTERVENTIONS FOR IPVR WITH THE

3214
01:57:44,146 --> 01:57:46,415
GOAL OF DEVELOPING A

3215
01:57:46,415 --> 01:57:47,115
DISCIPLINARY CISION MAKING TIEWL

3216
01:57:47,115 --> 01:57:49,217
WITH THE GOAL OF CLINICIANS THAT

3217
01:57:49,217 --> 01:57:52,354
HELP THE DISPARITIES FACED BY

3218
01:57:52,354 --> 01:57:55,424
THESE PARTICIPANTS.

3219
01:57:55,424 --> 01:57:56,358
NEXT SLIDE.

3220
01:57:56,358 --> 01:57:58,293
TO ASSIST THE NLM EXTRAMURAL

3221
01:57:58,293 --> 01:58:00,796
RESEARCH PROGRAM WITH ITS FUTURE

3222
01:58:00,796 --> 01:58:02,998
VISION FOR RESEARCH, NLM

3223
01:58:02,998 --> 01:58:04,466
RECENTLY RELEASEDDA A REQUEST

3224
01:58:04,466 --> 01:58:06,101
FOR INFORMATION, LOOKING FOR

3225
01:58:06,101 --> 01:58:08,503
FEEDBACK ON RESEARCH GAPS,

3226
01:58:08,503 --> 01:58:09,704
TRANSFORMATIVE OPPORTUNITIES,

3227
01:58:09,704 --> 01:58:11,740
AND UNEXPLORED AREAS THAT NLM

3228
01:58:11,740 --> 01:58:13,341
CAN ADDRESS THROUGH OUR

3229
01:58:13,341 --> 01:58:13,842
EXTRAMURAL PROGRAMS.

3230
01:58:13,842 --> 01:58:15,610
SO WE'RE LOOKING FOR THOUGHTS ON

3231
01:58:15,610 --> 01:58:19,081
BOLD STRATEGIES FOR AREAS SUCH

3232
01:58:19,081 --> 01:58:20,615
AS BIOMEDICAL INFORMATICS

3233
01:58:20,615 --> 01:58:21,783
EMERGING AI METHODOLOGIES AS

3234
01:58:21,783 --> 01:58:24,052
WELL AS FRAMEWORKS FOR SCALABLE

3235
01:58:24,052 --> 01:58:27,122
AND INNOVATIVE DATA SHARING AND

3236
01:58:27,122 --> 01:58:28,423
INTERDISCIPLINARY COLLABORATION.

3237
01:58:28,423 --> 01:58:29,891
SO THE INPUT WE RECEIVE WILL

3238
01:58:29,891 --> 01:58:32,727
HELP SHAPE THE FOUNDATION OF OUR

3239
01:58:32,727 --> 01:58:34,963
SCIENCE VISION, BY LINING FUTURE

3240
01:58:34,963 --> 01:58:37,065
INVESTMENTS WITH UNMET NEEDS AND

3241
01:58:37,065 --> 01:58:37,732
EMERGING OPPORTUNITIES INCLUDING

3242
01:58:37,732 --> 01:58:40,202
HOW THEY MAY ALIGN WITH RESEARCH

3243
01:58:40,202 --> 01:58:40,969
ON WOMEN'S HEALTH.

3244
01:58:40,969 --> 01:58:43,138
SO WE INVITE YOU TO SUBMIT

3245
01:58:43,138 --> 01:58:45,574
COMMENTS FOR THIS RFI BY

3246
01:58:45,574 --> 01:58:52,881
JULY 14th.

3247
01:58:52,881 --> 01:58:53,582
NEXT SLIDE.

3248
01:58:53,582 --> 01:58:56,284
AND THE FIRST VOICES AREN'T JUST

3249
01:58:56,284 --> 01:58:58,687
VALUABLE, THEY'RE ALSO VITAL IN

3250
01:58:58,687 --> 01:58:59,721
REPRESENTING WOMEN IN RESEARCH

3251
01:58:59,721 --> 01:59:01,823
AND IS JUST AS CRITICAL AS

3252
01:59:01,823 --> 01:59:04,392
REPRESENTING WOMEN THROUGH

3253
01:59:04,392 --> 01:59:05,560
RESEARCH AND DIVERSE POPULATION

3254
01:59:05,560 --> 01:59:06,928
CAN IMPACT BY O MEDICAL

3255
01:59:06,928 --> 01:59:09,498
DISCOVERY AS IT NATURALLY BRINGS

3256
01:59:09,498 --> 01:59:10,599
DIFFERENT INFORMATION, OPINIONS,

3257
01:59:10,599 --> 01:59:11,333
  PERSPEBILITYIVES AND

3258
01:59:11,333 --> 01:59:13,969
EXPERIENCES TO THE TABLE,

3259
01:59:13,969 --> 01:59:15,270
LEADING TO INCREASED CREATIVITY

3260
01:59:15,270 --> 01:59:19,875
INNOVATION AND MORE EFFECTIVE

3261
01:59:19,875 --> 01:59:20,609
DECISION MAKING.

3262
01:59:20,609 --> 01:59:21,877
MORE OPPORTUNITIES EXIST TO

3263
01:59:21,877 --> 01:59:23,311
DEVELOP AND ADVANCE THE CAREERS

3264
01:59:23,311 --> 01:59:25,280
OF WOMEN IN BIOMEDICAL RESEARCH,

3265
01:59:25,280 --> 01:59:28,483
TAKE OUR NLM RESEARCH GRANTS AND

3266
01:59:28,483 --> 01:59:30,785
BIOMEDICAL INFORMATICS AND DATA

3267
01:59:30,785 --> 01:59:34,956
SCIENCE WHICH SUPPORT INNOVATIVE

3268
01:59:34,956 --> 01:59:35,891
RESEARCH DECISION MAKING TO,A

3269
01:59:35,891 --> 01:59:38,226
PLIE THERAPY ANDEES AND

3270
01:59:38,226 --> 01:59:39,427
ANALYTERAL PROCESSES OR METHODS

3271
01:59:39,427 --> 01:59:39,861
TO DATA.

3272
01:59:39,861 --> 01:59:43,498
NOT ONLY DO THEY LOOK FOR

3273
01:59:43,498 --> 01:59:45,400
INNOVATIVE ANALYTIC METHODS THAT

3274
01:59:45,400 --> 01:59:47,636
ARE GENERALIZABLE WITHIN AND

3275
01:59:47,636 --> 01:59:48,537
ACROSS UNDERSERVED POPULATIONS

3276
01:59:48,537 --> 01:59:49,738
BUT THEY ALSO RECOGNIZE THE

3277
01:59:49,738 --> 01:59:51,673
IMPORTANCE OF DIVERSE

3278
01:59:51,673 --> 01:59:53,441
POPULATIONS INCLUDING THOSE FROM

3279
01:59:53,441 --> 01:59:53,775
WOMEN'S.

3280
01:59:53,775 --> 01:59:58,380
WE ALSO HAVE NLM CODE-A-THONs

3281
01:59:58,380 --> 02:00:00,015
WHERE RESEARCHERS AND COMPUTER

3282
02:00:00,015 --> 02:00:02,184
PROGRAMS FROM DIVERSE TECHNICAL

3283
02:00:02,184 --> 02:00:04,786
GABBING BROWNEDS COLLABORATE TO

3284
02:00:04,786 --> 02:00:06,521
CREATE SOFTWARE TOOLS FOR TO

3285
02:00:06,521 --> 02:00:08,390
SOLVE PROBLEMS IF ARE THE

3286
02:00:08,390 --> 02:00:09,057
BIOMEDICAL COMMUNITY.

3287
02:00:09,057 --> 02:00:10,859
IN 20 ARE 19 AFTER 5 YEARS OF

3288
02:00:10,859 --> 02:00:14,963
MORE THAN 40 CODE-A-THONs IN

3289
02:00:14,963 --> 02:00:19,434
NLM, THEY HOSTED THE FIRST ALL

3290
02:00:19,434 --> 02:00:20,969
WOMEN LED CODE-A-THON, ACROSS

3291
02:00:20,969 --> 02:00:21,970
INSTITUTES AND ACADEMIA AND

3292
02:00:21,970 --> 02:00:22,938
PRIVATE INDUSTRY.

3293
02:00:22,938 --> 02:00:24,639
SO HAVING THIS EVENT EXCLUSIVE

3294
02:00:24,639 --> 02:00:26,608
TO WOMEN EMPOWERED THEM TO

3295
02:00:26,608 --> 02:00:28,243
CREATE AN EXPERIENCE AND

3296
02:00:28,243 --> 02:00:31,746
CELEBRATED THEIR UNIQUE

3297
02:00:31,746 --> 02:00:33,215
PERSPECTIVES AND PROBLEM SOLVING

3298
02:00:33,215 --> 02:00:33,882
SKILLS.

3299
02:00:33,882 --> 02:00:35,850
THE PROJECTS THAT CAME FROM

3300
02:00:35,850 --> 02:00:40,889
THESE TEAMS RANGED FROM OVARIE,

3301
02:00:40,889 --> 02:00:44,659
WHICH IS AN OVERSOURCED GENE

3302
02:00:44,659 --> 02:00:48,263
PACKAGE TO FAN-RIERKS PACK, A

3303
02:00:48,263 --> 02:00:50,665
CODE CONVERTER FOR SCANNING USS

3304
02:00:50,665 --> 02:00:54,569
AND DIAGNOSES AND VIRAL-VDAPP,

3305
02:00:54,569 --> 02:00:58,273
ANN OITATION PIPELINE FOR VIRUS

3306
02:00:58,273 --> 02:01:00,442
VARIANTS.

3307
02:01:00,442 --> 02:01:01,109
NEXT SLIDE.

3308
02:01:01,109 --> 02:01:04,312
SO AS MENTIONED EARLIER SINCE

3309
02:01:04,312 --> 02:01:06,114
ITS INCEPTION, ORWH HAS WORKED

3310
02:01:06,114 --> 02:01:07,415
IN PARTNERSHIP WITH INSTITUTES

3311
02:01:07,415 --> 02:01:09,484
AND CENTERS ACROSS NIH TO

3312
02:01:09,484 --> 02:01:11,086
PRIORITIZE WOMEN'S HEALTH AND

3313
02:01:11,086 --> 02:01:12,020
THE RESEARCH PORTFOLIOS, AND

3314
02:01:12,020 --> 02:01:15,190
WHEN IT COMES TO WOMEN'S HEALTH,

3315
02:01:15,190 --> 02:01:17,292
THE MISSIONS OF ORWH AND NLM

3316
02:01:17,292 --> 02:01:21,162
COULD NOT BE MORE INTERTWINED OR

3317
02:01:21,162 --> 02:01:24,499
THE PARTNERSHIP OR SEAMLESS,

3318
02:01:24,499 --> 02:01:25,767
THIS COOPERATIVE RELATIONSHIP

3319
02:01:25,767 --> 02:01:31,973
BETWEEN NLM AND ORWH HAS ABOUT

3320
02:01:31,973 --> 02:01:33,608
KNOW INTEGRAL TO ADVANCING INIT

3321
02:01:33,608 --> 02:01:34,409
YAIF ITS.

3322
02:01:34,409 --> 02:01:36,077
THE CONTINUE CONTINUE TO PARTNER

3323
02:01:36,077 --> 02:01:37,712
ON INITIATIVES AND COLLABORATED

3324
02:01:37,712 --> 02:01:40,015
MORE CLEARS LOW ON COMMON DATA

3325
02:01:40,015 --> 02:01:44,586
DATA ELEMENTS THE VIFIANCE PENS

3326
02:01:44,586 --> 02:01:45,920
PROGRAM THAT DR. CLAYTON

3327
02:01:45,920 --> 02:01:49,457
MENTIONED AND AS WELL AS

3328
02:01:49,457 --> 02:01:50,125
DISCOVER WHR.

3329
02:01:50,125 --> 02:01:51,059
NEXT SLIDE.

3330
02:01:51,059 --> 02:01:53,161
SO 1 SUCH INITIATIVE WAS A JOINT

3331
02:01:53,161 --> 02:01:54,796
EFFORT TO IDENTIFY AND DEVELOP

3332
02:01:54,796 --> 02:01:55,363
COMMON DATA ELMETROPOLITANS

3333
02:01:55,363 --> 02:01:58,300
WHICH ARE THE STANDARD

3334
02:01:58,300 --> 02:01:59,234
STRUCTURE, MACHINE READABLE

3335
02:01:59,234 --> 02:02:00,902
DEFINITIONS OF DATA ELEMENTS,

3336
02:02:00,902 --> 02:02:02,637
VARIABLES AND MEASURES USED IN

3337
02:02:02,637 --> 02:02:06,274
RESEARCH, RELATED TO WOMEN'S

3338
02:02:06,274 --> 02:02:06,508
HEALTH.

3339
02:02:06,508 --> 02:02:09,210
THE CDEs HELP RESEARCHERS

3340
02:02:09,210 --> 02:02:18,520
SHARE AND COMBINE DATA SETS,

3341
02:02:18,520 --> 02:02:20,722
IMPROVE ACUREACY, AND THIS IS A

3342
02:02:20,722 --> 02:02:21,556
COLLABORATIVE FLAT FORM THAT

3343
02:02:21,556 --> 02:02:23,058
PROVIDES ACCESS TO STRUCTURED

3344
02:02:23,058 --> 02:02:25,160
HUMAN AND MACHINE READABLE

3345
02:02:25,160 --> 02:02:28,229
DEFINITIONS OF CDEs AND FORM

3346
02:02:28,229 --> 02:02:29,898
IN RESEARCH.

3347
02:02:29,898 --> 02:02:30,799
NLM MAKES THIS REPOSITORY

3348
02:02:30,799 --> 02:02:32,200
AVAILABLE FOR FREE TO ANYONE WHO

3349
02:02:32,200 --> 02:02:35,503
WANTS TO SHARE STANDARDIZED

3350
02:02:35,503 --> 02:02:38,506
DATA, ACROSS VARIOUS NIH FUNDED

3351
02:02:38,506 --> 02:02:39,407
RESEARCH PROJECTS, INCLUDING

3352
02:02:39,407 --> 02:02:42,243
THOSE ON WOMEN'S HEALTH.

3353
02:02:42,243 --> 02:02:43,545
CURRENTLY NLM DEVELOPED AND

3354
02:02:43,545 --> 02:02:45,280
MAINTAINS THIS RESOURCE AND

3355
02:02:45,280 --> 02:02:47,582
COLLABORATES WITH THE OFFICE OF

3356
02:02:47,582 --> 02:02:52,287
DATA SCIENCE STRATEGY IN ORPW

3357
02:02:52,287 --> 02:02:55,890
THE AUTOIMMUNE DISEASE RESEARCH

3358
02:02:55,890 --> 02:02:56,825
ON STANDARD INTEROPERABLE DATA

3359
02:02:56,825 --> 02:02:59,094
COLLECTION FOR PLIE OICITIS

3360
02:02:59,094 --> 02:02:59,828
RESEARCH INITIATIVE.

3361
02:02:59,828 --> 02:03:03,631
MYOCYTEIS IS A GROUP OF RARE

3362
02:03:03,631 --> 02:03:04,766
AUTOIMMUNE DECEASES THAT CAUSE

3363
02:03:04,766 --> 02:03:05,500
CHRONIC INFLAMMATION OF THE

3364
02:03:05,500 --> 02:03:09,037
MUSCLES AND LAST YEAR, LAST

3365
02:03:09,037 --> 02:03:11,339
FALL, NLM HOSTED AN

3366
02:03:11,339 --> 02:03:13,708
INTERNATIONAL EXPERT PANEL AT

3367
02:03:13,708 --> 02:03:16,244
THE FIRST MYOCYTEIS COMMON DATA

3368
02:03:16,244 --> 02:03:17,078
ELEMENTS WORKSHOP CONFERENCE TO

3369
02:03:17,078 --> 02:03:18,580
SET A COURSE OF INSTRUMENTS USED

3370
02:03:18,580 --> 02:03:21,116
TO DEVELOP A DATABASE OF

3371
02:03:21,116 --> 02:03:23,685
MYOCYTEIS CORE SET MEASURES.

3372
02:03:23,685 --> 02:03:24,719
PATIENT RECORDED OUTCOME

3373
02:03:24,719 --> 02:03:26,121
MEASURES, KEY MIGHT OICITIS

3374
02:03:26,121 --> 02:03:28,189
ASSESSMENT TOOLS AND A NATURAL

3375
02:03:28,189 --> 02:03:31,593
HISTORY OF CLINICAL TRIAL STUDY

3376
02:03:31,593 --> 02:03:31,860
FORMS.

3377
02:03:31,860 --> 02:03:34,396
CONSENSUS IN CODING IS EXPECTED

3378
02:03:34,396 --> 02:03:36,598
AND THE CDEs TO SERVE AS

3379
02:03:36,598 --> 02:03:38,967
PARADIGM FOR AUTOIMMUNE DISEASES

3380
02:03:38,967 --> 02:03:44,372
THAT DISPROPORTIONATELY AFFECT

3381
02:03:44,372 --> 02:03:45,006
WOMEN.

3382
02:03:45,006 --> 02:03:46,040
NEXT SLIDE.

3383
02:03:46,040 --> 02:03:47,108
NLM WAS ALSO PROUD TO

3384
02:03:47,108 --> 02:03:48,843
PARTICIPATE IN THE PLANNING AND

3385
02:03:48,843 --> 02:03:53,681
PRESENTING AT THE NINTH ANNUAL

3386
02:03:53,681 --> 02:03:55,617
VIVIAN PEN SYMPOSIUM LAST MONTH,

3387
02:03:55,617 --> 02:03:57,285
THIS YEAR'S FOCUS ON ADVANCING

3388
02:03:57,285 --> 02:03:58,286
DATA DRIVEN INFORMATION ON THE

3389
02:03:58,286 --> 02:04:00,622
HEALTH OF WOMEN WAS ON HOW DATA

3390
02:04:00,622 --> 02:04:02,257
SCIENCE SKILLS RESOURCES AND

3391
02:04:02,257 --> 02:04:05,059
TRAINING CAN BUILD CAPACITY FOR

3392
02:04:05,059 --> 02:04:05,860
INTERDISCIPLINARY DATA,AINAL SIS

3393
02:04:05,860 --> 02:04:07,896
FOR RESEARCH ON WOMEN'S HEALTH.

3394
02:04:07,896 --> 02:04:09,931
A PART OF THE MEETING INCLUDED

3395
02:04:09,931 --> 02:04:11,699
FLASH TALKS ON VARIOUS DATA

3396
02:04:11,699 --> 02:04:14,803
RESOURCES FROM ACROSS NIH THAT

3397
02:04:14,803 --> 02:04:16,504
ARE AVAILABLE TO THE PUBLIC FOR

3398
02:04:16,504 --> 02:04:19,040
RESEARCH AND 1 OF THESE

3399
02:04:19,040 --> 02:04:21,743
RESOURCES THAT WAS DESCRIBED WAS

3400
02:04:21,743 --> 02:04:24,045
DISCOVER WOMEN'S HEALTH RESEARCH

3401
02:04:24,045 --> 02:04:24,846
OR DISCOVER WHR.

3402
02:04:24,846 --> 02:04:26,481
AND IT'S AN INNOVATIVE RESOURCE

3403
02:04:26,481 --> 02:04:30,351
THAT WAS LAUNCHED BY AN NLM IN

3404
02:04:30,351 --> 02:04:38,560
ORWH COLLABORATION. 

3405
02:04:38,560 --> 02:04:39,227
NEXT SLIDE.

3406
02:04:39,227 --> 02:04:42,197
MANY OF YOU HAVE PROBABLY HEARD

3407
02:04:42,197 --> 02:04:43,965
DR. CLAYTON DISCOVER WHR, IT IS

3408
02:04:43,965 --> 02:04:45,133
A CENTRALIZED RESOURCE FOR

3409
02:04:45,133 --> 02:04:46,201
WOMEN'S HEALTH RESEARCH AND

3410
02:04:46,201 --> 02:04:48,770
INFORMATION THAT SUPPORTS NIH

3411
02:04:48,770 --> 02:04:50,271
WIDE EFFORTS TO CLOSE THE GAPS

3412
02:04:50,271 --> 02:04:51,639
IN WOMEN'S HEALTH ACROSS THE

3413
02:04:51,639 --> 02:04:53,842
LIFE COURSE.

3414
02:04:53,842 --> 02:04:54,776
THIS MAJOR INITIATIVE

3415
02:04:54,776 --> 02:04:56,177
DISTINGUISHED ITSELF FROM OTHER

3416
02:04:56,177 --> 02:04:58,813
RESOURCES BY OFFERING AN

3417
02:04:58,813 --> 02:05:00,548
EXTENSIVE OVERVIEW OF NIH

3418
02:05:00,548 --> 02:05:01,516
SUPPORTED WOMEN'S HEALTH

3419
02:05:01,516 --> 02:05:03,718
RESEARCH ENCLOUDING THE LATEST

3420
02:05:03,718 --> 02:05:04,986
DATA AND LITERATURE ON COMMON

3421
02:05:04,986 --> 02:05:07,155
HEALTH ISSUES THAT PRIMEAR LE

3422
02:05:07,155 --> 02:05:08,623
AFFECT OR OFTEN PRESENT

3423
02:05:08,623 --> 02:05:10,825
DIFFERENTLY IN WOMEN TO DRIVE

3424
02:05:10,825 --> 02:05:12,293
IMPACTFUL EVIDENCE BASED

3425
02:05:12,293 --> 02:05:15,763
SOLUTIONS THAT IMPROVE THEIR

3426
02:05:15,763 --> 02:05:16,030
HEALTH.

3427
02:05:16,030 --> 02:05:17,966
DISCOVER WHR ALSO SERVEs AS A

3428
02:05:17,966 --> 02:05:20,068
DISCOVERY PORTAL FOR

3429
02:05:20,068 --> 02:05:21,369
RESEARCHERS, HEALTHCARE

3430
02:05:21,369 --> 02:05:21,970
PROFESSIONALS, PATIENTS,

3431
02:05:21,970 --> 02:05:25,340
CAREGIVERS, AND THE PUBLIC, TO

3432
02:05:25,340 --> 02:05:27,275
EASILY DISCOVER THE LATEST

3433
02:05:27,275 --> 02:05:29,310
FINDINGS AND ONGOING WOMEN'S

3434
02:05:29,310 --> 02:05:31,045
HEALTH RESEARCH ACTIVITIES

3435
02:05:31,045 --> 02:05:33,548
INCLUDING NIH SUPPORTED

3436
02:05:33,548 --> 02:05:34,916
RESEARCH, CLINICAL TRIALS,

3437
02:05:34,916 --> 02:05:36,551
LITERATURE AND INFORMATION ON

3438
02:05:36,551 --> 02:05:38,920
ISSUES THAT UNIQUELY OR

3439
02:05:38,920 --> 02:05:40,188
DISPROPORTIONATELY AFFECT WOMEN

3440
02:05:40,188 --> 02:05:46,060
ACROSS THEIR LIFE SPAN, NEXT

3441
02:05:46,060 --> 02:05:46,594
SLIDE.

3442
02:05:46,594 --> 02:05:48,496
IN ITS INITIAL PHASE WE HAVE

3443
02:05:48,496 --> 02:05:50,265
PRIORITIZED 5 RESEARCH AREAS

3444
02:05:50,265 --> 02:05:51,666
BASED ON THEIR SIGNIFICANT

3445
02:05:51,666 --> 02:05:54,669
IMPACT ON WOMEN'S HEALTH

3446
02:05:54,669 --> 02:05:56,838
INCLUDING MENOPAUSE, POLICY

3447
02:05:56,838 --> 02:05:58,673
CYSTIC OVARIAN SYNDROME AND

3448
02:05:58,673 --> 02:06:02,877
OTHER SELECT AUTOIMMUNE DISEASES

3449
02:06:02,877 --> 02:06:04,812
INCLUDING LUPUS, AND AS OF

3450
02:06:04,812 --> 02:06:07,181
YESTERDAY, INFORMATION CAN NOW

3451
02:06:07,181 --> 02:06:10,618
BE FOUND ON ENDOMEET REOSEIS,

3452
02:06:10,618 --> 02:06:13,221
OVER TIME, USERS WILL BE ABLE TO

3453
02:06:13,221 --> 02:06:15,056
QUICKLY NAVIGATE TO AND SURVEY

3454
02:06:15,056 --> 02:06:17,225
THE LANDSCAPE OF NIH FUNDED

3455
02:06:17,225 --> 02:06:19,193
RESEARCH AND INFORMATION FOR

3456
02:06:19,193 --> 02:06:23,731
SPECIFIC WOMEN'S HEALTH RELATED

3457
02:06:23,731 --> 02:06:23,965
TOPICS.

3458
02:06:23,965 --> 02:06:25,433
NLM'S SPECIFIC SUPPORT COMES

3459
02:06:25,433 --> 02:06:28,036
FROM OUR RESEARCH PRODUCTS AND

3460
02:06:28,036 --> 02:06:29,804
SERVICES, FOR EXAMPLE, VISITORS

3461
02:06:29,804 --> 02:06:30,972
CAN STAY INFORMED WITH THE

3462
02:06:30,972 --> 02:06:32,707
REGULAR UPDATES FROM THE NIH

3463
02:06:32,707 --> 02:06:34,909
GUIDE FOR GRANTS AND CONTRACTS

3464
02:06:34,909 --> 02:06:35,577
ABOUT FUNDING OPPORTUNITIES REEL

3465
02:06:35,577 --> 02:06:38,513
KEEPSAKES VABT TO WOMEN'S HEALTH

3466
02:06:38,513 --> 02:06:41,049
EEXPLORE CURRENT AND PAST NIH

3467
02:06:41,049 --> 02:06:42,784
FUNDED PROJECTS, SOURCED FROM

3468
02:06:42,784 --> 02:06:46,220
THE NIH REPORTER SYSTEM,

3469
02:06:46,220 --> 02:06:49,023
COMPLETE WITH RELATED

3470
02:06:49,023 --> 02:06:50,491
PUBLICATIONS AND PATENTS,AX

3471
02:06:50,491 --> 02:06:52,794
ASSESSES DETAILED INFORMATION

3472
02:06:52,794 --> 02:06:55,229
FROM CLINICALTRIALS.GOV ON BOTH

3473
02:06:55,229 --> 02:06:56,030
ONGOING AND COMPLETED CLINICAL

3474
02:06:56,030 --> 02:06:57,432
TRIALS THAT ADDRESS WOMEN'S

3475
02:06:57,432 --> 02:06:59,567
HEALTH CONDITIONS AND ALSO

3476
02:06:59,567 --> 02:07:00,535
DISCUSS RELEVANT RESEARCH PAPERS

3477
02:07:00,535 --> 02:07:02,937
AND STUDIES ON WOMEN'S HEALTH

3478
02:07:02,937 --> 02:07:06,908
VIA PUB MED, PROVIDING EASY

3479
02:07:06,908 --> 02:07:08,643
ACCESS TO CREDIBLE INFORMATION

3480
02:07:08,643 --> 02:07:10,945
AND GUIDED BY NIH-WIDE STRATEGIC

3481
02:07:10,945 --> 02:07:12,580
PLAN FOR RESEARCH ON HEALTH OF

3482
02:07:12,580 --> 02:07:15,083
WOMEN AND USER FEEDBACK,

3483
02:07:15,083 --> 02:07:16,851
DISCOVER WHR WILL BE ENHANCED

3484
02:07:16,851 --> 02:07:18,586
WITH ADDITIONAL NIH FUNDED

3485
02:07:18,586 --> 02:07:20,655
RESEARCH TOPICS AND RESOURCES

3486
02:07:20,655 --> 02:07:23,524
COMMON DAT DATA ELEMENTS, DATA

3487
02:07:23,524 --> 02:07:23,992
SOURCES, STANDARDIZED

3488
02:07:23,992 --> 02:07:26,461
TERMINOLOGIES AS WELL AS

3489
02:07:26,461 --> 02:07:27,762
INCORPORATE DATA SCIENCE TOOLS

3490
02:07:27,762 --> 02:07:31,766
IN THE  FUTURE.

3491
02:07:31,766 --> 02:07:35,570
SO PLEASE KEEP YOUR EYE OUT ON

3492
02:07:35,570 --> 02:07:37,805
THE LATEST DISCOVERY WHR

3493
02:07:37,805 --> 02:07:38,039
WEBSITE.

3494
02:07:38,039 --> 02:07:38,373
NEXT SLIDE.

3495
02:07:38,373 --> 02:07:40,041
IN THE LAST FEW MINUTES I WOULD

3496
02:07:40,041 --> 02:07:42,210
JUST LIKE TO SHARE WITH YOU A

3497
02:07:42,210 --> 02:07:45,613
FEW METRICS ON DISCOVERY WHR.

3498
02:07:45,613 --> 02:07:48,483
SINCE ITS LAUNCH 9 MONTHS AGO,

3499
02:07:48,483 --> 02:07:50,351
IT'S BEEN ACCESSED BY OVER

3500
02:07:50,351 --> 02:07:52,286
25,000 UNIQUE USERS AND GARNERED

3501
02:07:52,286 --> 02:07:55,189
OVER 56,000 OVERALL VIEWS FROM

3502
02:07:55,189 --> 02:07:56,124
OVER 120 COUNTRIES, MOST OF THE

3503
02:07:56,124 --> 02:07:59,093
TRAFFIC TO THE WEBSITE HAS BEEN

3504
02:07:59,093 --> 02:08:01,062
THROUGH DIRECT LINKS MEANING

3505
02:08:01,062 --> 02:08:02,030
THAT DISCOVER WHR HAS BEEN

3506
02:08:02,030 --> 02:08:04,165
CREATING A LITTLE BIT OF A BUZZ

3507
02:08:04,165 --> 02:08:05,633
AND THE RESEARCH COMMUNITY AND

3508
02:08:05,633 --> 02:08:10,438
EVEN IN THE NEWS CYCLES.

3509
02:08:10,438 --> 02:08:11,072
NEXT SLIDE.

3510
02:08:11,072 --> 02:08:13,107
WE'RE PROUD TO SHOWCASE SOME OF

3511
02:08:13,107 --> 02:08:14,642
THE VARIOUS SOURCES WHERE OUR

3512
02:08:14,642 --> 02:08:17,412
VISITORS ARE COMING FROM AND THE

3513
02:08:17,412 --> 02:08:19,414
IMPACT ITS HAD ON DRIVING

3514
02:08:19,414 --> 02:08:20,114
READERS TO OUR SITE.

3515
02:08:20,114 --> 02:08:23,951
IN THIS CHART YOU WILL SEE THAT

3516
02:08:23,951 --> 02:08:25,386
THE NUMBERS, THE TRACKS IN THE

3517
02:08:25,386 --> 02:08:26,888
NUMBERS OF UNIQUE HITS PER WEEK,

3518
02:08:26,888 --> 02:08:29,090
YOU WILL NOTICE THAT THERE HAVE

3519
02:08:29,090 --> 02:08:31,159
BEEN SUG'RE SIGNIFICANT SPIKES

3520
02:08:31,159 --> 02:08:31,993
SINCE MIDDECEMBER, NOTABLY

3521
02:08:31,993 --> 02:08:32,860
FOLLOWING THE RELEASE OF

3522
02:08:32,860 --> 02:08:35,930
ARTICLES OR PAPERS THAT HAVE

3523
02:08:35,930 --> 02:08:37,765
MENTIONED DISCOVER WHR, SUCH AS

3524
02:08:37,765 --> 02:08:39,600
THE WASHINGTON POST ARTICLE, AN

3525
02:08:39,600 --> 02:08:44,572
ARTICLE IN  JAMA, AS WELL AS THE

3526
02:08:44,572 --> 02:08:51,512
OFFICE OF WOMEN'S HEALTH AT

3527
02:08:51,512 --> 02:08:52,013
WOMENSHEALTH .GOV.

3528
02:08:52,013 --> 02:08:54,315
SO WE HOPE THAT OOZE WE ADD NEW

3529
02:08:54,315 --> 02:08:55,383
TOPICS AND FEATURES MORE AND

3530
02:08:55,383 --> 02:08:57,318
MORE PEOPLE WILL CONTINUE TO USE

3531
02:08:57,318 --> 02:09:00,421
THIS INNOVATIVE RESOURCE.

3532
02:09:00,421 --> 02:09:01,422
NEXT SLIDE.

3533
02:09:01,422 --> 02:09:04,759
SO THE OFFICE OF THE ASSISTANT

3534
02:09:04,759 --> 02:09:10,765
SECRETARY FOR HEALTH OASH OFFERS

3535
02:09:10,765 --> 02:09:12,700
GUIDENESS ON THE PUBLIC CORPS

3536
02:09:12,700 --> 02:09:13,534
AND PUBLIC HEALTH SERVICE

3537
02:09:13,534 --> 02:09:14,368
AGENCIES AND EARLY THERAPY AND

3538
02:09:14,368 --> 02:09:17,672
YEAR THROUGH THE OFFICE OF

3539
02:09:17,672 --> 02:09:19,440
WOMEN'S HEALTH, OASH RELEASED A

3540
02:09:19,440 --> 02:09:20,475
WEBPAGE FOCUSED ON PROTECTING

3541
02:09:20,475 --> 02:09:22,710
WOMEN AND CHILDREN AND TO

3542
02:09:22,710 --> 02:09:23,978
SUPPORT INITIATIVES AIMED AT

3543
02:09:23,978 --> 02:09:25,513
IMPROVING THE HEALTH OF WOMEN IN

3544
02:09:25,513 --> 02:09:26,781
CHILDREN, THIS PAGE PROVIDES

3545
02:09:26,781 --> 02:09:29,350
LINKS TO VARIOUS RESOURCES AND

3546
02:09:29,350 --> 02:09:31,853
INFORMATION ENCLUEDING NIH

3547
02:09:31,853 --> 02:09:32,854
RESOURCES.

3548
02:09:32,854 --> 02:09:37,458
WHILE WE'RE EXCITED THAT BOTH

3549
02:09:37,458 --> 02:09:38,960
CLINICALTRIALS.GOV AND GOEVER

3550
02:09:38,960 --> 02:09:41,395
WHR ARE FEATURED PROMINENTLYOT

3551
02:09:41,395 --> 02:09:42,463
WEBSITE AND PROVIDES DIRECT

3552
02:09:42,463 --> 02:09:43,731
ACCESS TO RESEARCH INFORMATION

3553
02:09:43,731 --> 02:09:48,169
AND CLINICAL STUDIES ON WOMEN'S

3554
02:09:48,169 --> 02:09:50,872
HEALTH FROM NIH.

3555
02:09:50,872 --> 02:09:51,472
NEXT SLIDE.

3556
02:09:51,472 --> 02:09:54,909
SO RESEARCH ON WOMEN'S HEALTH

3557
02:09:54,909 --> 02:09:56,210
ISN'T A SIDE BAR, IT'S CENTRAL

3558
02:09:56,210 --> 02:09:57,879
TO THE MISSION OF NIH.

3559
02:09:57,879 --> 02:10:00,148
NLM HAS BEEN A HUB OF

3560
02:10:00,148 --> 02:10:01,849
INFORMATION AND PROMOTING AND

3561
02:10:01,849 --> 02:10:02,750
CHAMPIONING INITTIAIVE ITS THAT

3562
02:10:02,750 --> 02:10:04,852
BEST SERVICE WOMEN AND THEIR

3563
02:10:04,852 --> 02:10:06,687
HEALTHCARE NEEDS, AND THAT THEY

3564
02:10:06,687 --> 02:10:07,488
REQUIRE DATA HISTORY,

3565
02:10:07,488 --> 02:10:08,956
INFORMATION, AND THE NEXT

3566
02:10:08,956 --> 02:10:10,358
GENERATION OF RESEARCH IN ORDER

3567
02:10:10,358 --> 02:10:12,460
TO MOVE ALL OF THIS FORWARD.

3568
02:10:12,460 --> 02:10:15,096
SO FROM PIE O NEARING DATA

3569
02:10:15,096 --> 02:10:16,964
ACCESS TO ELEVATING INFORMATION,

3570
02:10:16,964 --> 02:10:18,332
NLM IS COMMITTED TO CONTRIBUTING

3571
02:10:18,332 --> 02:10:20,535
TO BUILDING A FUTURE OF RESEARCH

3572
02:10:20,535 --> 02:10:23,504
ON WOMEN'S HEALTH IN ORDER TO

3573
02:10:23,504 --> 02:10:25,673
IMPROVE HEALTH OVERALL.

3574
02:10:25,673 --> 02:10:27,308
OUR PRIORITIES MOVING FORWARD

3575
02:10:27,308 --> 02:10:29,544
ARE TO ADVANCE BIOMEDICAL

3576
02:10:29,544 --> 02:10:30,878
INFORMATICS AND COMPUTATIONAL

3577
02:10:30,878 --> 02:10:32,380
DATA HEALTH SCIENCE TO SUPPORT

3578
02:10:32,380 --> 02:10:35,249
QUALITY AND SUSTAINABILITY OF

3579
02:10:35,249 --> 02:10:37,318
BIOMEDICAL INFORMATION SERVICES

3580
02:10:37,318 --> 02:10:39,453
TO MODERNIZE NLM INFRASTRUCTURE

3581
02:10:39,453 --> 02:10:40,354
AND ORGANIZATION, AND CONTINUE

3582
02:10:40,354 --> 02:10:42,623
TO SHARE OUR EXPERT EEDZ AND

3583
02:10:42,623 --> 02:10:45,760
CONTRIBUTE TO NIH AND GOVERNMENT

3584
02:10:45,760 --> 02:10:47,595
WIDE PRIORITIES MANY OF WHICH

3585
02:10:47,595 --> 02:10:51,065
WERE MENTIONED BY

3586
02:10:51,065 --> 02:10:51,699
DR. KLEINSTEUER, SO THANK YOU

3587
02:10:51,699 --> 02:10:53,501
FOR THE OPPORTUNITY TO SHARE

3588
02:10:53,501 --> 02:10:54,936
THIS OVERVIEW OF NLM AND WHAT WE

3589
02:10:54,936 --> 02:10:56,904
DO AND FOR YOUR ONGOING SUPPORT

3590
02:10:56,904 --> 02:10:58,306
OF THE TEAMS, RESEARCHERS AND

3591
02:10:58,306 --> 02:10:59,941
PARTNERS WHO MAKE ADVANCING

3592
02:10:59,941 --> 02:11:02,276
WOMEN'S HEALTH POSSIBLE, AND TO

3593
02:11:02,276 --> 02:11:03,177
BENEFIT EVERYONE.

3594
02:11:03,177 --> 02:11:05,112
YOU WILL HEAR MORE THIS

3595
02:11:05,112 --> 02:11:06,614
AFTERNOON, IN DATA SCIENCE AND

3596
02:11:06,614 --> 02:11:11,018
WOMEN'S HEALTH PANEL ABOUT

3597
02:11:11,018 --> 02:11:12,286
SPECIFIC DATA AND DATA SCIENCE

3598
02:11:12,286 --> 02:11:13,821
PROJECTS THAT ARE FOSTERING AND

3599
02:11:13,821 --> 02:11:16,123
ADVANCING THE HEALTH OF WOMEN.

3600
02:11:16,123 --> 02:11:18,826
NLM IS HAPPY TO BE AMONGST THE

3601
02:11:18,826 --> 02:11:19,894
SUPPORTERS OF FACILITATORS OF

3602
02:11:19,894 --> 02:11:21,662
DATA DRIVEN APPROACHES TO FOSTER

3603
02:11:21,662 --> 02:11:26,133
DATA POWERED HEALTH.

3604
02:11:26,133 --> 02:11:26,467
NEXT SLIDE.

3605
02:11:26,467 --> 02:11:29,003
SO I WOULD LIKE TO THANK ORWH

3606
02:11:29,003 --> 02:11:30,605
FOR THE INVITATION TO PRESENT

3607
02:11:30,605 --> 02:11:34,308
TODAY AND FOR ITS ONGOING

3608
02:11:34,308 --> 02:11:34,976
MUTUALLY BENEFICIAL PARTNERSHIP

3609
02:11:34,976 --> 02:11:36,277
AND I WOULD LIKE TO THANK KEY

3610
02:11:36,277 --> 02:11:39,881
MEMBERS FROM MY TEAM, LIZ AMOS,

3611
02:11:39,881 --> 02:11:41,148
LIZ FOX, MLM POLICY TEAM AND

3612
02:11:41,148 --> 02:11:43,351
OTHERS FOR THEIR CONTRIBUTIONS

3613
02:11:43,351 --> 02:11:46,454
TO THIS PRESENTATION.

3614
02:11:46,454 --> 02:11:47,355
NEXT SLIDE.

3615
02:11:47,355 --> 02:11:49,257
AND WITH THAT I WOULD LIKE TO

3616
02:11:49,257 --> 02:11:51,058
CONCLUDE MY PRESENTATIONS AND

3617
02:11:51,058 --> 02:11:52,793
I'M HAPPY TO ANSWER ANY

3618
02:11:52,793 --> 02:11:54,262
QUESTIONS YOU MAY HAVE, EITHER

3619
02:11:54,262 --> 02:11:58,399
NOW OR IN THE DISCUSSION PORTION

3620
02:11:58,399 --> 02:11:59,901
OF THE MEETING. 

3621
02:11:59,901 --> 02:12:00,768
THANK YOU.

3622
02:12:00,768 --> 02:12:04,405
>> THANK YOU SO MUCH DR. P
A

3623
02:12:04,405 --> 02:12:07,875
LTOO, WHAT A WHIRL WIND TOUR.

3624
02:12:07,875 --> 02:12:09,176
YOU REALLY WOWED ME HERE, AND

3625
02:12:09,176 --> 02:12:10,444
THAT'S NOT EASY TO DO.

3626
02:12:10,444 --> 02:12:12,613
SO THANK YOU SO MUCH FOR SHARING

3627
02:12:12,613 --> 02:12:15,917
WITH OUR COLLEAGUES AND WITH THE

3628
02:12:15,917 --> 02:12:17,451
PUBLIC ALL THE INCREDIBLE WORK

3629
02:12:17,451 --> 02:12:19,220
THAT'S HAPPENING AT NLM, WHAT'S

3630
02:12:19,220 --> 02:12:20,955
BEHIND ALL THOSE TOOLS THAT WE

3631
02:12:20,955 --> 02:12:23,925
USE SO EASILY AND WHAT IT TAKES

3632
02:12:23,925 --> 02:12:26,193
TO ADVANCE DATA SCIENCE AND WHAT

3633
02:12:26,193 --> 02:12:28,429
IT TAKES TO LEVERAGE ALL THE NIH

3634
02:12:28,429 --> 02:12:29,497
RESOURCES TO MOVE INTO THE

3635
02:12:29,497 --> 02:12:32,033
FUTURE AND OUR LONG-TERM

3636
02:12:32,033 --> 02:12:32,867
NATTERRENERSHIP, WE GREATLY

3637
02:12:32,867 --> 02:12:33,434
APPRECIATE THAT.

3638
02:12:33,434 --> 02:12:38,105
IT LOOKS LOAMACYIC DR. GARY HAS

3639
02:12:38,105 --> 02:12:38,873
HIS HAND UP?

3640
02:12:38,873 --> 02:12:41,742
>> THANK YOU SO MUCH, IN

3641
02:12:41,742 --> 02:12:43,644
DR. CLAYTON'S WORDS IT WAS AN

3642
02:12:43,644 --> 02:12:46,013
ENORMOUS,AMOUNT OF INFORMATION.

3643
02:12:46,013 --> 02:12:48,482
IT'S REALLY IMPORTANT TO, YOU

3644
02:12:48,482 --> 02:12:54,255
KNOW WE USE PUB MED AND DBGAP, I

3645
02:12:54,255 --> 02:12:57,525
USE A VARIETY OF RESOURCES AND I

3646
02:12:57,525 --> 02:12:59,260
JUST WANTED TO GIVE A BIG SHOUT

3647
02:12:59,260 --> 02:13:01,662
OUT TO YOU GUYS, WE SOMETIMES

3648
02:13:01,662 --> 02:13:04,999
TAKE THAT AMOUNT OF GRANTED AND

3649
02:13:04,999 --> 02:13:06,033
IT'S AN ENORMOUS AMOUNT OF

3650
02:13:06,033 --> 02:13:07,201
STRUCTURALLY TOWER MAINTAIN ON A

3651
02:13:07,201 --> 02:13:09,003
REGULAR BASIS SO THANK YOU FOR

3652
02:13:09,003 --> 02:13:10,037
MAKING OUR LIVES EASY AND

3653
02:13:10,037 --> 02:13:11,806
RESEARCH BETTER AS WELL.

3654
02:13:11,806 --> 02:13:14,375
I THINK 1 QUESTION THAT I DID

3655
02:13:14,375 --> 02:13:17,912
HAVE FOR YOU WAS, AND I REALLY

3656
02:13:17,912 --> 02:13:20,915
LOVE THE DISCOVER WHR PAGE IN

3657
02:13:20,915 --> 02:13:22,883
COLLABORATION WITH ORWH, I THINK

3658
02:13:22,883 --> 02:13:24,485
THAT'S A REALLY GREAT PLATFORM

3659
02:13:24,485 --> 02:13:26,954
TO INFORM THE PUBLIC AS WELL AND

3660
02:13:26,954 --> 02:13:28,522
USED FOR RESEARCH AS WELL, I WAS

3661
02:13:28,522 --> 02:13:29,690
PLAYING AROUND WITH IT, JUST

3662
02:13:29,690 --> 02:13:31,125
RIGHT NOW AS YOU WERE TALKING

3663
02:13:31,125 --> 02:13:34,495
AND JUST SO MUCH MORE EASIER TO

3664
02:13:34,495 --> 02:13:35,596
FIND GRANTS BASED ON SPECIFIC

3665
02:13:35,596 --> 02:13:36,864
TOPICS AND REALLY LOOKING

3666
02:13:36,864 --> 02:13:38,132
FORWARD TO SORT OF THAT

3667
02:13:38,132 --> 02:13:40,868
EXPANSION OF MUCH MORE, I WAS

3668
02:13:40,868 --> 02:13:43,471
WONDERING, I GUESS 1   PERINENT

3669
02:13:43,471 --> 02:13:46,374
QUESTION IS, WILL THIS ALSO

3670
02:13:46,374 --> 02:13:48,676
INCLUDE PREGNANCY SPECIFIC SORT

3671
02:13:48,676 --> 02:13:49,744
OF PHENOTYPES AS WELL OR IS THAT

3672
02:13:49,744 --> 02:13:52,480
GOING TO BE CONSIDERED   PERVIEW

3673
02:13:52,480 --> 02:13:56,450
OF LIKE A DIFFERENT IC?

3674
02:13:56,450 --> 02:13:57,718
>> YEAH, WE -- YOU KNOW AS
YOU

3675
02:13:57,718 --> 02:13:58,719
MENTIONED AND AS I MENTIONED

3676
02:13:58,719 --> 02:14:01,122
THIS, THIS IS A PARTNERSHIP WITH

3677
02:14:01,122 --> 02:14:02,823
ORWH AND WE'RE ALSO PARTNERING

3678
02:14:02,823 --> 02:14:06,827
WITH OTHER STAFF ACROSS THE NIH,

3679
02:14:06,827 --> 02:14:08,929
TO KIND OF PRIORITIZE THE

3680
02:14:08,929 --> 02:14:10,331
DIFFERENT TOPIC TO ENCLOUD, SO I

3681
02:14:10,331 --> 02:14:12,466
WOULD SAY NOTHING IS OFF THE

3682
02:14:12,466 --> 02:14:13,934
TABLE.

3683
02:14:13,934 --> 02:14:15,302
WE ARE CONSIDERING DIFFERENT

3684
02:14:15,302 --> 02:14:17,104
TOPICS BUT WE ALSO, THERE'S ALSO

3685
02:14:17,104 --> 02:14:19,173
A BUTTON ON THE WEBSITE WHERE

3686
02:14:19,173 --> 02:14:21,042
YOU CAN PROSLIDE FEEDBACK AND IF

3687
02:14:21,042 --> 02:14:23,277
THERE'S A PARTICULAR TOPIC

3688
02:14:23,277 --> 02:14:24,245
THAT'S OF INTEREST, OR THAT YOU

3689
02:14:24,245 --> 02:14:27,715
FEEL THAT WE SHOULD PRIORITIZE,

3690
02:14:27,715 --> 02:14:29,250
PLEASE SHARE THAT.

3691
02:14:29,250 --> 02:14:31,919
WE REALLY APPRECIATE EVERYONE'S

3692
02:14:31,919 --> 02:14:33,888
FEEDBACK AND WE KIND OF DEFER TO

3693
02:14:33,888 --> 02:14:35,823
OUR SUBJECT MATTER EXPERTS WITH

3694
02:14:35,823 --> 02:14:38,159
REGARDS TO THE WOMEN'S HEALTH

3695
02:14:38,159 --> 02:14:46,700
RESEARCH TOPICS TO INCLUDE.

3696
02:14:46,700 --> 02:14:49,737
NTHANK YOU.

3697
02:14:49,737 --> 02:14:52,640
>> THANK YOU.

3698
02:14:52,640 --> 02:14:53,974
>> DR. WELAND, THANK YOU
FOR THE

3699
02:14:53,974 --> 02:14:55,776
AMAZING OVERVIEW FOR US, REALLY

3700
02:14:55,776 --> 02:14:56,544
ENJOYED THAT.

3701
02:14:56,544 --> 02:14:59,180
AGAIN, THIS IS A BROAD QUESTION,

3702
02:14:59,180 --> 02:15:01,916
I WAS WONDERING, YOU KNOW AS YOU

3703
02:15:01,916 --> 02:15:06,153
TOUCH OFFICE OF DIVERSITY THIS

3704
02:15:06,153 --> 02:15:07,555
IN VARIOUS PLACES HOW YOU KNOW

3705
02:15:07,555 --> 02:15:12,493
DATA SCIENCE AND USING OUR AI

3706
02:15:12,493 --> 02:15:14,995
METHODOLOGIES ARE GOING TO BE

3707
02:15:14,995 --> 02:15:16,263
APPLIED AND UPDATED.

3708
02:15:16,263 --> 02:15:18,966
I WONDERED IF THERE WERE ANY

3709
02:15:18,966 --> 02:15:20,935
SPECIFIC INITIATIVES YOU KNOW

3710
02:15:20,935 --> 02:15:24,405
FOCUSED ON YOUR PRODUCTS OR

3711
02:15:24,405 --> 02:15:26,607
SERVICES YOU KNOW WITH LIKE PUB

3712
02:15:26,607 --> 02:15:28,075
MED IS SOMEONE WORKING ON USING

3713
02:15:28,075 --> 02:15:30,277
AI OR IS IT ALREADY USING --

3714
02:15:30,277 --> 02:15:31,946
JUST WONDERED HOW ALL THAT WAS

3715
02:15:31,946 --> 02:15:37,017
-- IF THOSE PRODUCTS ARE BEING

3716
02:15:37,017 --> 02:15:39,420
UPDATED OR WILL THEY BE REPLACED

3717
02:15:39,420 --> 02:15:40,888
WITH DIFFERENT PRODUCTS.

3718
02:15:40,888 --> 02:15:41,255
THANKS.

3719
02:15:41,255 --> 02:15:43,190
>> I WOULD SAY WE'RE
AUGMENTS

3720
02:15:43,190 --> 02:15:46,827
AND UPDATING NOT NECESSARILY

3721
02:15:46,827 --> 02:15:47,528
REPLACING.

3722
02:15:47,528 --> 02:15:49,063
NLM ALSO LEADS A COMMUNITY OF

3723
02:15:49,063 --> 02:15:51,732
PRACTICE OF AI, AT THE NIH AND

3724
02:15:51,732 --> 02:15:54,101
ARE INTRAMURAL RESEARCH PROGRAM

3725
02:15:54,101 --> 02:15:56,971
LEADS MANY OF THE AI ACTIVITIES

3726
02:15:56,971 --> 02:15:59,773
AT NIH, BUT WE ARE ALREADY

3727
02:15:59,773 --> 02:16:01,475
INCORPORATING SOME OF THAT

3728
02:16:01,475 --> 02:16:02,643
BEHIND THE SCENES FOR SOME OF

3729
02:16:02,643 --> 02:16:05,613
OUR PRODUCTS AND SERVICES, BUT

3730
02:16:05,613 --> 02:16:07,815
AS WE CONTINUE TO MODERNIZE OUR

3731
02:16:07,815 --> 02:16:09,250
PRODUCTS AND SERVICES, WE WILL

3732
02:16:09,250 --> 02:16:13,320
BE INCORPORATING MORE OF THAT

3733
02:16:13,320 --> 02:16:14,255
MOVING FORWARD.

3734
02:16:14,255 --> 02:16:16,190
>> GREAT. 

3735
02:16:16,190 --> 02:16:19,627
THANK YOU.

3736
02:16:19,627 --> 02:16:20,261
>> DR. JONES?

3737
02:16:20,261 --> 02:16:23,430
>> YES, THANK YOU DR. P A
LTOO,

3738
02:16:23,430 --> 02:16:26,901
OH MY GOODNESS I AM IN AWE AND

3739
02:16:26,901 --> 02:16:28,435
INCREDIBLE LOAMACYY JUST

3740
02:16:28,435 --> 02:16:29,970
OVERWHELMED WITH THE BREDTH AND

3741
02:16:29,970 --> 02:16:35,042
DEPRIVATIONTH OF  -- DEPTH OF

3742
02:16:35,042 --> 02:16:37,811
WHAT YOU ALL DO AND WHAT AN

3743
02:16:37,811 --> 02:16:38,979
INCREDIBLE NATIONAL TREASURE

3744
02:16:38,979 --> 02:16:40,648
THIS SERVICE IS FOR THE PUBLIC.

3745
02:16:40,648 --> 02:16:43,784
I WAS WONDERING, THIS IS A VERY

3746
02:16:43,784 --> 02:16:44,385
SMALL SUGGESTION BUT

3747
02:16:44,385 --> 02:16:45,085
COMMUNICATING THE NUMBERS THAT

3748
02:16:45,085 --> 02:16:47,821
YOU SHARED WITH US, ABOUT THE

3749
02:16:47,821 --> 02:16:49,023
NUMBER OF USERS ACCIDENT THE

3750
02:16:49,023 --> 02:16:52,760
AMOUNT OF DATA THAT IS PROVIDED

3751
02:16:52,760 --> 02:16:54,962
TO THE PUBLIC FOR THE U.S. AND

3752
02:16:54,962 --> 02:16:56,363
AROUND THE WORLD, HAVE YOU EVER

3753
02:16:56,363 --> 02:16:57,898
THOUGHT OF PUTTING ON YOUR

3754
02:16:57,898 --> 02:16:59,867
WEBSITE THOSE NUMBERS, LIKE A

3755
02:16:59,867 --> 02:17:01,202
COUNTER, LIKE A DASHBOARD

3756
02:17:01,202 --> 02:17:05,606
BECAUSE I FEEL LIKE THAT NEEDS

3757
02:17:05,606 --> 02:17:07,641
TO BE A HIGHLIGHTED, CELEBRATED

3758
02:17:07,641 --> 02:17:09,376
AND PEOPLE NEED TO KNOW ABOUT

3759
02:17:09,376 --> 02:17:10,911
THIS, AND I DIDN'T KNOW ABOUT IT

3760
02:17:10,911 --> 02:17:12,546
UNTIL YOU SHARED IT SO THANK

3761
02:17:12,546 --> 02:17:12,780
YOU.

3762
02:17:12,780 --> 02:17:15,950
>> YEAH, WE PROBABLY COULD
DO A

3763
02:17:15,950 --> 02:17:23,991
LITTLE BIT OF A BETTER JOB

3764
02:17:23,991 --> 02:17:24,592
HIGHLIGHTING SOME OF THAT BUT

3765
02:17:24,592 --> 02:17:25,192
THIS IS ALSO 1 OF THE REASONS

3766
02:17:25,192 --> 02:17:27,127
WHY I WANTED TO SHARE WITH ALL

3767
02:17:27,127 --> 02:17:29,363
OF YOU WHAT NLM DOES AND WHO WE

3768
02:17:29,363 --> 02:17:31,832
ARE, KIND OF ALL THE THINGS THAT

3769
02:17:31,832 --> 02:17:33,534
WE MAINTAIN BECAUSE MOST PEOPLE

3770
02:17:33,534 --> 02:17:34,635
DO NOT KNOW.

3771
02:17:34,635 --> 02:17:37,972
AND WE'VE HAD JUST A GRIT

3772
02:17:37,972 --> 02:17:39,006
PARTNERSHIP WITH ORWH, AND YOU

3773
02:17:39,006 --> 02:17:41,141
KNOW OUR SERVICE TO THE

3774
02:17:41,141 --> 02:17:42,643
COMMUNITY IS WHAT WE'RE HERE

3775
02:17:42,643 --> 02:17:44,845
FOR, BUT THANK YOU FOR THAT

3776
02:17:44,845 --> 02:17:45,846
SUGGESTION.

3777
02:17:45,846 --> 02:17:47,381
WE WILL CONTINUE TO STRIVE ON

3778
02:17:47,381 --> 02:17:54,421
HOW WE CAN HIGHLIGHT OUR WORK.

3779
02:17:54,421 --> 02:17:57,224
OTHER QUESTIONS OR COMMENTS FOR

3780
02:17:57,224 --> 02:18:03,097
DR. P A LTOO?

3781
02:18:03,097 --> 02:18:04,164
I THINK WE ALREADY LOOKED AT

3782
02:18:04,164 --> 02:18:10,104
THAT COMMENT IN THE CHAT, OKAY,

3783
02:18:10,104 --> 02:18:14,308
WE'VE GOT SOME SECONDS DEHIND

3784
02:18:14,308 --> 02:18:15,342
DR. JONES COMMENTS.

3785
02:18:15,342 --> 02:18:17,811
DINA I WANT TO ALSO THANK YOU

3786
02:18:17,811 --> 02:18:19,480
FOR ANNOUNCING TODAY THAT

3787
02:18:19,480 --> 02:18:23,550
ENDOMEET REOSEIS HAS BEEN ADDED

3788
02:18:23,550 --> 02:18:25,819
TO DISCOVER WHR SIGNIFICANT

3789
02:18:25,819 --> 02:18:27,121
WOMEN'S HEALTH ISSUE, CHALLENGES

3790
02:18:27,121 --> 02:18:31,292
IN GETTING TIMELY DIAGNOSIS,

3791
02:18:31,292 --> 02:18:32,159
HIGHLY PREVALENT AND IMPORTANT

3792
02:18:32,159 --> 02:18:33,427
TOPIC FOR THE HEALTH OF WOMEN,

3793
02:18:33,427 --> 02:18:36,397
SO THANK YOU SO MUCH FOR MOVING

3794
02:18:36,397 --> 02:18:42,002
FORWARD AND GETTING ENDOMEET

3795
02:18:42,002 --> 02:18:43,904
RIOOSEIS UP AND ON WHR, WE

3796
02:18:43,904 --> 02:18:44,705
CONTINUE TO LOOKING FORWARD TO

3797
02:18:44,705 --> 02:18:46,006
WORK WITH YOU AND YOUR TEAM ON

3798
02:18:46,006 --> 02:18:48,075
THE OTHER TOPIC ANDS ON DORPH

3799
02:18:48,075 --> 02:18:50,978
WHR AND ALL THE OTHER AMAZING

3800
02:18:50,978 --> 02:18:54,415
PRODUCTS AND EFFORTS UNDERWAY.

3801
02:18:54,415 --> 02:18:57,051
I THINK THAT THE LIBRARY OF THE

3802
02:18:57,051 --> 02:18:58,786
FUTURE IS SO EXCITING, LIBRARIES

3803
02:18:58,786 --> 02:19:00,854
ARE LIKE MY NUMBER 1 FAVORITE

3804
02:19:00,854 --> 02:19:02,256
PLACE IN THE WORLD IN REAL LIFE

3805
02:19:02,256 --> 02:19:04,224
BUT I THINK WILL I HAVE TO

3806
02:19:04,224 --> 02:19:06,226
EXPAND THAT TO THE VIRTUAL

3807
02:19:06,226 --> 02:19:09,263
LIBRARY AS WELL AND I JUST AM

3808
02:19:09,263 --> 02:19:10,431
PLEASED THAT YOU WERE ABLE TO

3809
02:19:10,431 --> 02:19:11,932
SHARE WITH THE PUBLIC THE

3810
02:19:11,932 --> 02:19:15,703
AMAZING WORK AND EFFORTS AND

3811
02:19:15,703 --> 02:19:17,771
PERSISTENCE AND RIGOR THAT YOU

3812
02:19:17,771 --> 02:19:21,208
ALL ARE APPROACHING THESE DATA

3813
02:19:21,208 --> 02:19:22,476
RELATED RESOURCES AND I LOVE

3814
02:19:22,476 --> 02:19:24,011
YOUR PHRASE, DATA POWERED

3815
02:19:24,011 --> 02:19:24,244
HEALTH.

3816
02:19:24,244 --> 02:19:27,381
I WROTE THAT DOWN, YOU KNOW,

3817
02:19:27,381 --> 02:19:29,083
THAT IS EXACTLY WHEN WE TALK

3818
02:19:29,083 --> 02:19:32,720
ABOUT EVIDENCE BASED MEDICINE,

3819
02:19:32,720 --> 02:19:35,622
YOU KNOW I THINK WE MOVE TO THE

3820
02:19:35,622 --> 02:19:37,024
NEXT LEVEL WITH DATA POWER

3821
02:19:37,024 --> 02:19:38,625
HEALTH AND YOU AND YOUR

3822
02:19:38,625 --> 02:19:40,060
LEADERSHIP AND DR. SHERRY AND

3823
02:19:40,060 --> 02:19:41,095
OTHERS HAVE BEEN IMPORTANT IN

3824
02:19:41,095 --> 02:19:42,963
THAT SO THANK YOU SO MUCH FOR

3825
02:19:42,963 --> 02:19:44,331
YOUR PARTNERSHIP AND YOU ARE

3826
02:19:44,331 --> 02:19:46,266
WELCOME TO STAY BUT WE KNOW

3827
02:19:46,266 --> 02:19:48,035
EVERYONE HAS A BUSY SCHEDULE, SO

3828
02:19:48,035 --> 02:19:49,870
WE WILL NOT AT ALL BE OFFEND

3829
02:19:49,870 --> 02:19:51,305
FEDERAL YOU HAVE TO STEP OFF.

3830
02:19:51,305 --> 02:19:53,207
SO THANK YOU GAIN, DINA,

3831
02:19:53,207 --> 02:19:54,808
PREECIAL REALLY APPRECIATE IT.

3832
02:19:54,808 --> 02:19:56,443
>> THANK YOU F YOUR
LEADERSHIP

3833
02:19:56,443 --> 02:19:57,778
DR. CLAYTON AND FOR YOUR

3834
02:19:57,778 --> 02:19:58,946
CONTINUED PARTNERSHIP,

3835
02:19:58,946 --> 02:20:00,881
APPRECIATE IT.

3836
02:20:00,881 --> 02:20:01,482
>> MY PLEASURE.

3837
02:20:01,482 --> 02:20:01,782
MY PLEASURE.

3838
02:20:01,782 --> 02:20:03,817
WITH THAT I THINK WE ARE GOING

3839
02:20:03,817 --> 02:20:06,687
TO MOVE TO OUR OPEN SESSION FOR

3840
02:20:06,687 --> 02:20:10,190
OUR ADVISORY COMMITTEE MEMBERS.

3841
02:20:10,190 --> 02:20:12,226
OF AND SO, THIS IS AN

3842
02:20:12,226 --> 02:20:19,366
OPPORTUNITY FOR YOU TO SHARE

3843
02:20:19,366 --> 02:20:21,435
YOUR THOUGHTS AND WE REALLY

3844
02:20:21,435 --> 02:20:23,537
WELCOME OUR INPUT ON FUTURE

3845
02:20:23,537 --> 02:20:24,138
PROGRAMMING, CURRENT

3846
02:20:24,138 --> 02:20:25,406
PROGRAMMING, YOUR FEEDBACK ON

3847
02:20:25,406 --> 02:20:26,273
ITEMS YOU SEE, THAT YOU WOULD

3848
02:20:26,273 --> 02:20:29,176
LIKE TO SEE MORE OF, THINGS THAT

3849
02:20:29,176 --> 02:20:33,313
YOU THINKER MISSING, GAPS  GAPSD

3850
02:20:33,313 --> 02:20:34,581
OPPORTUNITIES WE WELCOME IT ALL.

3851
02:20:34,581 --> 02:20:36,683
SO FEEL FREE TO RAISE YOUR HAND

3852
02:20:36,683 --> 02:20:37,918
OR COME ON CAMERA IF YOU WOULD

3853
02:20:37,918 --> 02:20:48,328
LIKE TO MAKE A COMMENT.

3854
02:20:55,736 --> 02:20:57,504
YOU ALL ARE VERY QUIET TODAY, IF

3855
02:20:57,504 --> 02:20:59,273
YOU WERE IN PERSON, I WOULD CALL

3856
02:20:59,273 --> 02:20:59,740
ON YOU.

3857
02:20:59,740 --> 02:21:01,809
I WILL NOT DO THAT.

3858
02:21:01,809 --> 02:21:03,877
I CAN STILL CALL BUT YOU KNOW, I

3859
02:21:03,877 --> 02:21:10,384
CAN'T GIVE THEM THE EYE. 

3860
02:21:10,384 --> 02:21:13,320
THERE, ANDERSON AND DR., LET'S

3861
02:21:13,320 --> 02:21:14,288
GO.

3862
02:21:14,288 --> 02:21:18,292
>> OKAY, THANK YOU.

3863
02:21:18,292 --> 02:21:19,693
DR. ANDERSON, BREAK THE ICE I

3864
02:21:19,693 --> 02:21:22,196
LITTLE BIT BUT I DIDN'T HEAR --

3865
02:21:22,196 --> 02:21:25,632
I CERTAINLY DIDN'T HEAR MUCH

3866
02:21:25,632 --> 02:21:27,234
ABOUT MATERNAL MORTALITY AND THE

3867
02:21:27,234 --> 02:21:28,268
VERY, VERY IMPORTANT WORK THAT

3868
02:21:28,268 --> 02:21:29,803
WE NEED TO DO THERE, CAN YOU

3869
02:21:29,803 --> 02:21:32,406
GIVE US AN UPDATE ON WHAT'S

3870
02:21:32,406 --> 02:21:37,377
HAPPENING IN THAT REALM?

3871
02:21:37,377 --> 02:21:39,446
>> MATERNAL MORTALITY.

3872
02:21:39,446 --> 02:21:40,647
>> MATERNAL MORTALITY
CONTINUES

3873
02:21:40,647 --> 02:21:42,449
TO BE A REALLY IMPORTANT AREA

3874
02:21:42,449 --> 02:21:44,284
FOR WOMEN'S HELT.

3875
02:21:44,284 --> 02:21:46,086
DATA, THE DATA ARE THE BOTTOM

3876
02:21:46,086 --> 02:21:49,623
LINE, WE CONTINUE TO SEE VERY

3877
02:21:49,623 --> 02:21:50,624
DISTURBING RATES OF MATERNAL

3878
02:21:50,624 --> 02:21:51,758
MORTALITY IN THE UNITED STATES,

3879
02:21:51,758 --> 02:21:54,428
SO I WOULD POINT YOU TO OUR -- 1

3880
02:21:54,428 --> 02:21:56,964
OF OUR CENTER FEASS AT NIH, NOT

3881
02:21:56,964 --> 02:21:58,999
THE ONLY BUT 1 OF THE

3882
02:21:58,999 --> 02:22:00,400
CENTERPIECE SYSTEM THE IMPROVE

3883
02:22:00,400 --> 02:22:03,136
INITIATIVE WHICH IS NOW

3884
02:22:03,136 --> 02:22:04,271
CONGRESSALLY FUNDED FOR THE PAST

3885
02:22:04,271 --> 02:22:06,173
FEW YEARS AND WE HAVE MULTIPLE

3886
02:22:06,173 --> 02:22:08,575
CENTERS OF EXCELLENCE ACROSS THE

3887
02:22:08,575 --> 02:22:13,814
COUNTRY AND ADDITIONAL

3888
02:22:13,814 --> 02:22:15,182
COMMUNITY-BASED PROGRAMMING AS

3889
02:22:15,182 --> 02:22:20,587
WELL WE PARTNER WIDE NHLBI WITH

3890
02:22:20,587 --> 02:22:24,825
OUR CYST COMMUNITY

3891
02:22:24,825 --> 02:22:27,861
IMPLEMENTATION PROGRAMS IN

3892
02:22:27,861 --> 02:22:30,697
ADDITION WITH THE IMPROVE MOVE

3893
02:22:30,697 --> 02:22:34,568
AM, AND THE DIRECTORS, THERE ARE

3894
02:22:34,568 --> 02:22:36,436
A VARIETY OF EFFORTS LED BY

3895
02:22:36,436 --> 02:22:38,005
INSURE MARKET TOO UTR ALONG

3896
02:22:38,005 --> 02:22:40,741
THEIR SPECIFIC MISSION AREAS AS

3897
02:22:40,741 --> 02:22:44,611
YOU'VE HEARD FROM THE PREVIOUS

3898
02:22:44,611 --> 02:22:49,316
PRESENTATIONS, THERE IS ADDED

3899
02:22:49,316 --> 02:22:51,985
VALUE AND POWER IN COMPOUNDING

3900
02:22:51,985 --> 02:22:54,788
OUR ACTIVITIES TOGETHER, LIKE

3901
02:22:54,788 --> 02:22:57,758
COMPOUNDED INTEREST, SO MATERNAL

3902
02:22:57,758 --> 02:23:00,160
MORBIDITY AND MORTALITY IS 1 OF

3903
02:23:00,160 --> 02:23:01,328
THOSE TOPICS TO IMPROVE AND WE

3904
02:23:01,328 --> 02:23:02,496
ARE HOPING TO GENERATE MORE THAT

3905
02:23:02,496 --> 02:23:05,532
EVIDENCE COULD LEAD TO

3906
02:23:05,532 --> 02:23:07,467
IMPLEMENTATION AT THE LEVEL OF

3907
02:23:07,467 --> 02:23:09,069
COMMUNITIES WHICH IS WHERE WE

3908
02:23:09,069 --> 02:23:14,575
NEED TO SEE THE IMPACT.

3909
02:23:14,575 --> 02:23:15,542
SO THAT'S JUST 1 PIECE OF WHAT

3910
02:23:15,542 --> 02:23:18,045
WE'RE DOING AND I DO WANT TO

3911
02:23:18,045 --> 02:23:20,013
MENTION THAT EEUNICE KENNEDY

3912
02:23:20,013 --> 02:23:21,548
SHRIVER NATIONAL INTUITY OF

3913
02:23:21,548 --> 02:23:23,150
CHILD AND HUMAN DEVELOPMENT IS

3914
02:23:23,150 --> 02:23:27,054
THE NIH LEAD FOR MATERNAL AND

3915
02:23:27,054 --> 02:23:27,854
MORBIDITY MORTALITY RESEARCH AND

3916
02:23:27,854 --> 02:23:29,089
THEY HAVE A VARIETY OF

3917
02:23:29,089 --> 02:23:30,924
COMMITTEES AND EFFORTS OF THEIR

3918
02:23:30,924 --> 02:23:32,793
OWN, THAT THEY LEAD AS THEY MOVE

3919
02:23:32,793 --> 02:23:34,161
FORWARD IN TRYING TO MAP OUT

3920
02:23:34,161 --> 02:23:43,704
THEIR STRAY  -- STRATEGIC AGEND.

3921
02:23:43,704 --> 02:23:44,871
>> THANK TUMOR SPECTRUM
DOES

3922
02:23:44,871 --> 02:23:46,239
SEEM IT WOULD CROSS

3923
02:23:46,239 --> 02:23:47,040
MULTIPETRESSABLE INSTITUTES AND

3924
02:23:47,040 --> 02:23:49,643
YOUR GROUP MIGHT BE THE MOST

3925
02:23:49,643 --> 02:23:52,079
IMPORTANT 1 IN FACILITATING

3926
02:23:52,079 --> 02:23:52,813
THAT.

3927
02:23:52,813 --> 02:23:54,448
>> YOU KNOW THEY'RE ALL

3928
02:23:54,448 --> 02:23:57,184
IMPORTANT, BUT WE HAVE HEARD

3929
02:23:57,184 --> 02:23:59,386
ACTUALLY ABOUT MATERNAL

3930
02:23:59,386 --> 02:24:00,053
MORBIDITY AND MORTALITY.

3931
02:24:00,053 --> 02:24:01,455
ONE THING IS TO LINK IT TO THE

3932
02:24:01,455 --> 02:24:04,691
FULL LIFE COURSE AND WITH YOUR

3933
02:24:04,691 --> 02:24:05,292
BACKGROUND GARNET, YOU CAN'T

3934
02:24:05,292 --> 02:24:09,162
THINK OF IT JUST AS THIS 1 SLICE

3935
02:24:09,162 --> 02:24:11,431
IN TIME THAT MIGHT BE A

3936
02:24:11,431 --> 02:24:13,634
ASSOCIATE WIDE REPRODUCTION,

3937
02:24:13,634 --> 02:24:14,334
THERE'S AN ENTIRE LIFE FOCUSED

3938
02:24:14,334 --> 02:24:16,203
ONS ARE AND WHAT HAPPENS BEFORE,

3939
02:24:16,203 --> 02:24:18,338
THE HELT OF WOMEN BEFORE THEY

3940
02:24:18,338 --> 02:24:21,508
BECOME PREGNANT IS AN AREA THEY

3941
02:24:21,508 --> 02:24:23,777
THINK IS AN OPPORTUNITY AND THE

3942
02:24:23,777 --> 02:24:27,214
HEALTH OF WOMEN IN MIDLIFE, SO

3943
02:24:27,214 --> 02:24:29,182
CONNECTING THOSE DOTS ACROSS

3944
02:24:29,182 --> 02:24:31,818
THAT LIFE COURSE AND PROVIDING A

3945
02:24:31,818 --> 02:24:33,086
SCIENTIFIC FRAMEWORK, FOR HOW

3946
02:24:33,086 --> 02:24:36,123
THOSE PIECES FIT TOGETHER, IS

3947
02:24:36,123 --> 02:24:38,692
YOU KNOW AN OVERALL ORWH

3948
02:24:38,692 --> 02:24:40,427
APPROACH TO HOW WE INTERACT WITH

3949
02:24:40,427 --> 02:24:41,061
THE ICs.

3950
02:24:41,061 --> 02:24:42,996
IT SOUNDS LIKE IT MIGHT BE OF

3951
02:24:42,996 --> 02:24:44,297
INTEREST TO YOU TO HEAR AN

3952
02:24:44,297 --> 02:24:45,932
UPDATE IN THE FUTURE MEETING

3953
02:24:45,932 --> 02:24:48,769
ABOUT SOME OF THOSE ACTIVITIES.

3954
02:24:48,769 --> 02:24:49,136
>> ABSOLUTELY.

3955
02:24:49,136 --> 02:24:49,770
THANK YOU.

3956
02:24:49,770 --> 02:24:50,037
>> OKAY.

3957
02:24:50,037 --> 02:24:57,310
WE'RE HAPPY TO DO THAT.

3958
02:24:57,310 --> 02:24:58,745
>> DR. INIIE, DID YOU HAVE
A

3959
02:24:58,745 --> 02:24:59,780
COMEBT OR QUESTION?

3960
02:24:59,780 --> 02:25:00,180
>> I DID.

3961
02:25:00,180 --> 02:25:04,251
THESE ARE GREAT  GREAT TO HEAR L

3962
02:25:04,251 --> 02:25:05,552
THE PROGRESS, WE SEE IT IN

3963
02:25:05,552 --> 02:25:06,987
PIECES THROUGHOUT THE YEAR BUT

3964
02:25:06,987 --> 02:25:10,390
REALLY GOOD TO HEAR AND ALSO THE

3965
02:25:10,390 --> 02:25:18,198
NATIONAL LIBRARY OF INSIDE THERE

3966
02:25:18,198 --> 02:25:19,599
WERE WITHIN ORWH, THERE WERE

3967
02:25:19,599 --> 02:25:20,267
FUNDING OPPORTUNITIES AND

3968
02:25:20,267 --> 02:25:21,401
RESOURCES BUT I WANTED TO KNOW

3969
02:25:21,401 --> 02:25:23,303
IF THERE WAS ANY POTENTIAL FOR

3970
02:25:23,303 --> 02:25:25,505
COLLABORATING FURTHER ON SOME OF

3971
02:25:25,505 --> 02:25:28,842
THE ELEARNING MODULES THAT WOULD

3972
02:25:28,842 --> 02:25:31,111
HELP RESEARCHERS CONTINUE

3973
02:25:31,111 --> 02:25:31,812
LEARNING SEX DIFFERENCES WOULD

3974
02:25:31,812 --> 02:25:35,949
WORK AND THEN WORK IN WOMEN'S

3975
02:25:35,949 --> 02:25:36,183
HEALTH?

3976
02:25:36,183 --> 02:25:37,918
>> THANK YOU SO MUCH FOR
THAT

3977
02:25:37,918 --> 02:25:40,120
QUESTION IRENE, OUR ELEARNING

3978
02:25:40,120 --> 02:25:41,955
MODULES ARE AN IMPORTANT TOOL IN

3979
02:25:41,955 --> 02:25:43,657
RESOURCE FOR THE COMMUNITY AS

3980
02:25:43,657 --> 02:25:46,359
YOU SAID TO ADVANCE SEX

3981
02:25:46,359 --> 02:25:47,761
DIFFERENCES RESEARCH AND WE ARE

3982
02:25:47,761 --> 02:25:51,498
IN THE PROCESS OF UPDATING

3983
02:25:51,498 --> 02:25:52,966
SEVERAL OF THEM, ARE THERE

3984
02:25:52,966 --> 02:25:54,534
COMMUNITIES FOR ADDITIONAL

3985
02:25:54,534 --> 02:25:54,868
PARTNERSHIP.

3986
02:25:54,868 --> 02:25:56,470
WE'RE ALWAYS INTERESTED IN

3987
02:25:56,470 --> 02:25:58,538
EXPANDING OUR REACH AND OUR

3988
02:25:58,538 --> 02:25:59,606
IMPACT AND I THINK 1 OF THE

3989
02:25:59,606 --> 02:26:01,274
THINGS WE WANT TO MAKE SURE IS

3990
02:26:01,274 --> 02:26:02,876
THAT WE'RE NOT DUPLICATING

3991
02:26:02,876 --> 02:26:05,412
EFFORTS ACROSS THE RESEARCH

3992
02:26:05,412 --> 02:26:07,814
ECOSYSTEM, SO, WITH PARTNERS

3993
02:26:07,814 --> 02:26:11,384
SUCH AS SWHR AND OTHERS, AND

3994
02:26:11,384 --> 02:26:12,452
REALLY SWHR'S MOVED INTO THAT

3995
02:26:12,452 --> 02:26:14,654
SPACE WITH A LOT OF THE

3996
02:26:14,654 --> 02:26:17,491
CONTINUING EDUCATION AND OTHER

3997
02:26:17,491 --> 02:26:21,161
ORGANIZATIONS AS WELL, AS THEY

3998
02:26:21,161 --> 02:26:23,396
REALIZE SEX DIFFERENCES ARE SO

3999
02:26:23,396 --> 02:26:25,565
SALIENT TO SO MANY DISEASE

4000
02:26:25,565 --> 02:26:26,867
AREAS, THEY'RE EMBEDDING IT,

4001
02:26:26,867 --> 02:26:28,034
THEY'RE EMBEDDING IT MORE AND

4002
02:26:28,034 --> 02:26:31,538
MORE IN OTHER ACTIVITIES, BUT WE

4003
02:26:31,538 --> 02:26:39,913
ARE WELCOME THE OPPORTUNITY TO

4004
02:26:39,913 --> 02:26:46,019
COLLABORATE WITH OTHER KEY

4005
02:26:46,019 --> 02:26:48,088
INTERESTED AREAS IN THE SPACE

4006
02:26:48,088 --> 02:26:49,256
SOPHISTICATED WORK NOR

4007
02:26:49,256 --> 02:26:50,423
COLLECTIVELY SO WE DON'T

4008
02:26:50,423 --> 02:26:54,261
DUPLICATE OUR EFFORTS AND OUR

4009
02:26:54,261 --> 02:26:55,028
EFFORTS SEAMLESSLY BENEFIT

4010
02:26:55,028 --> 02:26:55,362
EVERYONE.

4011
02:26:55,362 --> 02:26:58,465
SO HAPPY TO FOLLOW UP ON THAT.

4012
02:26:58,465 --> 02:26:58,765
>> THANKS.

4013
02:26:58,765 --> 02:27:00,901
>> AND KUDOS TO YOU FOR
CITING

4014
02:27:00,901 --> 02:27:02,536
SOME NEW PROGRAMS I'VE BEEN

4015
02:27:02,536 --> 02:27:04,805
SEEING ON WOMEN'S HEALTH I'VE

4016
02:27:04,805 --> 02:27:07,240
BEEN SEEING, NEW PROGRAMMING.

4017
02:27:07,240 --> 02:27:09,409
OKAY, AND JUST SO FOLKS DIDN'T

4018
02:27:09,409 --> 02:27:13,146
KNOW OUR ELEARNING COURSES HAVE

4019
02:27:13,146 --> 02:27:15,515
CONTINUING EDUCATION CREDITS ARE

4020
02:27:15,515 --> 02:27:21,822
AND FREELYY VAIL  -- AVAILABLE,E

4021
02:27:21,822 --> 02:27:24,024
WILL LET YOU KNOW WHEN THE NEXT

4022
02:27:24,024 --> 02:27:24,691
SET IS AVAILABLE.

4023
02:27:24,691 --> 02:27:26,393
AND IT LOOKS LIKE DR. MELAND

4024
02:27:26,393 --> 02:27:28,028
WOULD LIKE TO ADD?

4025
02:27:28,028 --> 02:27:29,296
>> YES, JUST WONDERING IF
THERE

4026
02:27:29,296 --> 02:27:32,032
WERE ANY UPDATES ON LONG COVID?

4027
02:27:32,032 --> 02:27:35,368
I KNOW THERE WAS AN IMPORTANT

4028
02:27:35,368 --> 02:27:38,038
JAMA METE YORK PAPER LOOKING AT

4029
02:27:38,038 --> 02:27:43,677
SEX DIFFERENCES IN LONG COVID

4030
02:27:43,677 --> 02:27:44,978
PUBLISHED JANUARY 2025, THAT

4031
02:27:44,978 --> 02:27:47,447
FOUND FEMALES HAD SIGNIFICANTLY

4032
02:27:47,447 --> 02:27:49,983
HIGH RISK OF LONG COVID COMPARED

4033
02:27:49,983 --> 02:27:51,284
TO MALES, SO WONDER IF THERE

4034
02:27:51,284 --> 02:27:52,686
WERE ANY UPDATES THERE?

4035
02:27:52,686 --> 02:28:01,294
>> THANK YOU DR. MELENZ
FOR YOUR

4036
02:28:01,294 --> 02:28:03,930
QUESTION. 

4037
02:28:03,930 --> 02:28:04,998
SEX DISAGGREGATION IS SO

4038
02:28:04,998 --> 02:28:05,599
IMPORTANT AND FINDING

4039
02:28:05,599 --> 02:28:06,867
INFORMATION ON THAT. I DO NOT

4040
02:28:06,867 --> 02:28:07,767
HAVE NOW INFORMATION ON LONG

4041
02:28:07,767 --> 02:28:09,736
COVID AND I WOULD REFER YOU

4042
02:28:09,736 --> 02:28:11,137
PERHAPS TO SOME OF THE WEBSITES

4043
02:28:11,137 --> 02:28:16,443
THAT ARE AVAILABLE ONLINE FOR

4044
02:28:16,443 --> 02:28:17,510
NIH   PERWHAPS THE RECOVER

4045
02:28:17,510 --> 02:28:19,579
WEBSITE MIGHT BE 1 YOU COULD GET

4046
02:28:19,579 --> 02:28:21,648
MORE UPTO GATE INFORMATION. 

4047
02:28:21,648 --> 02:28:29,522
>> GREAT, YEAH, THANKS.

4048
02:28:29,522 --> 02:28:31,291
>> ARE THERE TOPICS THAT
THE

4049
02:28:31,291 --> 02:28:32,626
ADVISORY MEMBERS WOULD LIKE TO

4050
02:28:32,626 --> 02:28:34,861
SEE AT A FUTURE MEETING?

4051
02:28:34,861 --> 02:28:36,529
WE'VE GOTTEN VALUABLE INPUT,

4052
02:28:36,529 --> 02:28:37,297
DR. NOEL?

4053
02:28:37,297 --> 02:28:38,398
>> I JUST HAD A QUICK
QUESTION

4054
02:28:38,398 --> 02:28:42,502
AND I GUESS IT COULD GO WITH

4055
02:28:42,502 --> 02:28:45,639
ALSO MAYBE SOMETHING WE CAN

4056
02:28:45,639 --> 02:28:47,741
MENTION IN THE FUTURE MEETINGS

4057
02:28:47,741 --> 02:28:52,212
WOULD BE REGARDING BREAST CANCER

4058
02:28:52,212 --> 02:28:55,515
AND THE PRESENCE OF DENSE BREAST

4059
02:28:55,515 --> 02:29:00,053
OR AT MAMMOGRAPHY HAVING THE

4060
02:29:00,053 --> 02:29:00,854
DENSE BREAST DESIGNATION AND

4061
02:29:00,854 --> 02:29:04,858
THAT BEING I THINK A BIT MORE

4062
02:29:04,858 --> 02:29:06,559
PRESENT IN UNDERREPRESENTED

4063
02:29:06,559 --> 02:29:08,895
MINORITY OR BLACK WOMEN AND HOW

4064
02:29:08,895 --> 02:29:10,864
THAT CAN BE ADDRESSED IN TERMS

4065
02:29:10,864 --> 02:29:12,832
OF BREAST CANCER RISK AND HOW

4066
02:29:12,832 --> 02:29:15,902
MAMMOGRAPHY CAN BE USEFUL FOR

4067
02:29:15,902 --> 02:29:18,438
BREAST CANCER DETECTION WITHIN

4068
02:29:18,438 --> 02:29:18,939
THAT POPULATION.

4069
02:29:18,939 --> 02:29:21,641
IS THERE ANYTHING THAT IS DONE

4070
02:29:21,641 --> 02:29:23,543
IN TERMS OF RESEARCH OR IS THAT

4071
02:29:23,543 --> 02:29:25,178
SOMETHING THAT COULD BE LOOKED

4072
02:29:25,178 --> 02:29:27,914
AT IN FUTURE RESEARCH.

4073
02:29:27,914 --> 02:29:32,752
>> THANK YOU SO MUCH DR.
NOEL,

4074
02:29:32,752 --> 02:29:34,487
THIS ISSUE OF DENSE BREAST

4075
02:29:34,487 --> 02:29:38,425
TISSUE AND IT'S AFFECT ON THE

4076
02:29:38,425 --> 02:29:40,727
DETECTION OF BREAST CANCER IS A

4077
02:29:40,727 --> 02:29:44,030
VERY IMPORTANT 1, EMERGING

4078
02:29:44,030 --> 02:29:44,698
EVOLVING 1.

4079
02:29:44,698 --> 02:29:46,533
IT DOES IMMEDIATELY ALSO

4080
02:29:46,533 --> 02:29:49,069
INTERSECT WITH OUR INTEREST IN

4081
02:29:49,069 --> 02:29:50,971
IMPROVING METHODOLOGIES IN

4082
02:29:50,971 --> 02:29:52,706
IMAGING AND TECHNOLOGIES.

4083
02:29:52,706 --> 02:29:55,575
AND WE HAVE PARTNERS WITH NIBIB

4084
02:29:55,575 --> 02:29:57,544
ON THAT AND HAVE SOME WORK IN

4085
02:29:57,544 --> 02:29:59,346
THAT SPACE THAT WE'VE SUPPORTED

4086
02:29:59,346 --> 02:30:01,448
BUT YOU'RE RIGHT ASTERISKS AN

4087
02:30:01,448 --> 02:30:02,582
EEMERGENCYING ISSUE OF

4088
02:30:02,582 --> 02:30:04,417
IMPORTANCE AND AFFECTS

4089
02:30:04,417 --> 02:30:05,819
POPULATIONS DIFFERENTLY WE WILL

4090
02:30:05,819 --> 02:30:09,622
BE HAPPY TO TAKE THAT ON AND HOW

4091
02:30:09,622 --> 02:30:11,691
WE CAN INTEGRATE THAT INTO

4092
02:30:11,691 --> 02:30:12,592
FUTURE MEETINGS.

4093
02:30:12,592 --> 02:30:19,666
IMPORTANT TOPIC AND THANK YOU.

4094
02:30:19,666 --> 02:30:21,067
OTHER QUESTIONS OR COMMENTS.

4095
02:30:21,067 --> 02:30:27,374
TOPICS YOU WANT TO HEAR ABOUT IN

4096
02:30:27,374 --> 02:30:36,082
THE FUTURE?

4097
02:30:36,082 --> 02:30:40,487
WE ARE A LITTLE EARLY FOR OUR

4098
02:30:40,487 --> 02:30:42,389
BREAK, BUT WE APPRECIATE THE

4099
02:30:42,389 --> 02:30:45,258
GIFT OF TIME AND IT'S BUSY, BUSY

4100
02:30:45,258 --> 02:30:46,693
TIME AND A BUSY DAY.

4101
02:30:46,693 --> 02:30:48,895
WOULD YOU LIKE TO GO AHEAD AND

4102
02:30:48,895 --> 02:30:50,764
DO OUR PHOTO AND BREAK EARLY?

4103
02:30:50,764 --> 02:30:52,999
>> YEAH, I THINK WHAT WE
SHOULD

4104
02:30:52,999 --> 02:30:56,002
DO IS MAYBE GIFT OURSELVES A BIT

4105
02:30:56,002 --> 02:30:57,003
LONGER LUNCH BREAK.

4106
02:30:57,003 --> 02:30:59,706
SO FIRST OF OF ALL I JUST WANT

4107
02:30:59,706 --> 02:31:00,840
TO SAY --

4108
02:31:00,840 --> 02:31:02,142
>> DR. THERE ARE A COUPLE

4109
02:31:02,142 --> 02:31:03,777
QUESTIONS I SAW --

4110
02:31:03,777 --> 02:31:05,512
>> I'M SORRY, WE'RE NOT
SEEING,

4111
02:31:05,512 --> 02:31:06,813
WE'RE ONLY SEEING 1 SCREEN SO WE

4112
02:31:06,813 --> 02:31:11,017
DON'T SEE THE FULL GALLERY, GO

4113
02:31:11,017 --> 02:31:11,418
AHEAD DR. JONES?

4114
02:31:11,418 --> 02:31:12,685
>> OH THANK YOU YEAH, I
WAS

4115
02:31:12,685 --> 02:31:16,990
GOING TO RAISE THE ISSUE OF

4116
02:31:16,990 --> 02:31:20,126
DEMENTIA AND ALZHEIMERS AND JUST

4117
02:31:20,126 --> 02:31:22,796
THINKING ABOUT AS THE LIFE

4118
02:31:22,796 --> 02:31:23,630
SPANNED, WE'RE LIVING LONGER IT

4119
02:31:23,630 --> 02:31:26,166
SEEMS LIKE THAT IS A TOPIC ON

4120
02:31:26,166 --> 02:31:27,801
MANY PEOPLE'S MINDS AND THINKING

4121
02:31:27,801 --> 02:31:32,772
ABOUT THE UNIQUE RISKS THAT

4122
02:31:32,772 --> 02:31:34,541
WOMEN HAVE WITH DEMENTIA AND

4123
02:31:34,541 --> 02:31:35,475
ALZHEIMERS SO ANYTHING THAT'S

4124
02:31:35,475 --> 02:31:37,710
JUST A TOPIC I THINK WOULD BE OF

4125
02:31:37,710 --> 02:31:38,178
INTEREST, THANK YOU?

4126
02:31:38,178 --> 02:31:43,083
>> THANK YOU SO MUCH, YES,

4127
02:31:43,083 --> 02:31:48,021
ABSOLUTELY.

4128
02:31:48,021 --> 02:31:48,488
DR. SHARPS?

4129
02:31:48,488 --> 02:31:50,090
WE'RE NOT HEARING YOU

4130
02:31:50,090 --> 02:31:51,291
DR. SHARPS, LOOKS LIKE YOU'RE

4131
02:31:51,291 --> 02:31:51,724
MUTED?

4132
02:31:51,724 --> 02:31:54,294
>> YEAH, I WANTED TO
COMMEND YOU

4133
02:31:54,294 --> 02:31:58,932
AND THE OFFICE ON THE IMPRESSIVE

4134
02:31:58,932 --> 02:32:01,868
WERE PORT FOAL DWROA THAT YOU

4135
02:32:01,868 --> 02:32:03,570
AREY PORTED ON -- PORTFOLIO THAT

4136
02:32:03,570 --> 02:32:04,804
YOU REPORT OFFICE OF DIVERSITY

4137
02:32:04,804 --> 02:32:06,539
IN THESE CHALLENGING TIMES AND I

4138
02:32:06,539 --> 02:32:09,175
AM CERTAINLY GRAD TO SEE THE

4139
02:32:09,175 --> 02:32:10,343
EMPHASIS ON POPULATION HEALTH

4140
02:32:10,343 --> 02:32:11,511
BUT WHAT I'M NOT HEARING AND I

4141
02:32:11,511 --> 02:32:13,379
KNOW IT'S PROBABLY A PART OF THE

4142
02:32:13,379 --> 02:32:17,584
TIMES BUT WE KNOW WOMEN ARE NOT

4143
02:32:17,584 --> 02:32:19,052
HETEROGENIUS GROUP AND DIFFERENT

4144
02:32:19,052 --> 02:32:21,921
POPULATIONS WITHIN THE

4145
02:32:21,921 --> 02:32:22,822
POPULATION HAVE DIFFERENT

4146
02:32:22,822 --> 02:32:25,358
DISEASE BURDEN SO I HOPE WE

4147
02:32:25,358 --> 02:32:26,593
CONTINUE -- ARE ABLE TO CONTINUE

4148
02:32:26,593 --> 02:32:29,429
TO FOCUS ON THAT AND I THINK IN

4149
02:32:29,429 --> 02:32:31,631
THE FUTURE, WE DIPPED A LITTLE

4150
02:32:31,631 --> 02:32:35,135
BIT INTO AI, BUT I THINK

4151
02:32:35,135 --> 02:32:36,302
CONTINUING LOOKING AT TECHNOLOGY

4152
02:32:36,302 --> 02:32:38,671
AND HOW IT'S INFORMING OR BEING

4153
02:32:38,671 --> 02:32:39,372
INTERNATIONAL CLASSIFICATION

4154
02:32:39,372 --> 02:32:41,808
GRAYED IN WOMEN'S HEALTH

4155
02:32:41,808 --> 02:32:44,210
RESEARCH AS WELL AS HOW IT WORKS

4156
02:32:44,210 --> 02:32:45,378
IN DIFFERENT COMMUNITIES AND

4157
02:32:45,378 --> 02:32:47,514
DIFFERENT POPULATIONS AND I

4158
02:32:47,514 --> 02:32:50,316
THINK WOULD BE CONTINUED FOCUS

4159
02:32:50,316 --> 02:32:52,018
FOR FUTURE MEETINGS.

4160
02:32:52,018 --> 02:32:56,222
>> THANK YOU SO MUCH DR.
SHARP,

4161
02:32:56,222 --> 02:32:57,290
I APPRECIATE THAT.

4162
02:32:57,290 --> 02:32:58,825
CERTAINLY CONTINUE TO BE

4163
02:32:58,825 --> 02:33:00,326
PROMOTING AND ADVANCING AND

4164
02:33:00,326 --> 02:33:02,028
INCLUSION OF WOMEN AND

4165
02:33:02,028 --> 02:33:05,899
INDIVIDUALS FROM RACIAL AND

4166
02:33:05,899 --> 02:33:09,369
ETHNIC UNDERREPRESENTED GROUPS

4167
02:33:09,369 --> 02:33:10,103
PER LEGISLATION AND IMPORTANT

4168
02:33:10,103 --> 02:33:12,038
FOR OUR RESEARCH TO BE ABLE TO

4169
02:33:12,038 --> 02:33:15,942
ADDRESS AND INCLUDE ALL

4170
02:33:15,942 --> 02:33:17,510
INDIVIDUALS WHO ARE AFFECTED BY

4171
02:33:17,510 --> 02:33:18,444
DECS AND CONDITIONS, WE STUDY

4172
02:33:18,444 --> 02:33:19,879
AND MAKE SURE WE UNDERSTAND WHO

4173
02:33:19,879 --> 02:33:22,682
WHOM OUR RESULTSA, PLIE.

4174
02:33:22,682 --> 02:33:25,185
SO HAPPY TO CONTINUE OUR SUPPORT

4175
02:33:25,185 --> 02:33:26,953
OF THAT EFFORT, THOSE EFFORTS

4176
02:33:26,953 --> 02:33:29,522
AND I APPRECIATE THE SUGGESTIONS

4177
02:33:29,522 --> 02:33:30,657
FOR TOPICS.

4178
02:33:30,657 --> 02:33:33,726
ARE THERE OTHER SUGGESTIONS FOR

4179
02:33:33,726 --> 02:33:36,129
TOPICS FOR OTHER COMMENTS THAT

4180
02:33:36,129 --> 02:33:37,297
OUR ADVISORY MEMBERS WOULD LIKE

4181
02:33:37,297 --> 02:33:37,797
TO ADD?

4182
02:33:37,797 --> 02:33:38,731
AND YOU CAN CERTAINLY DO THAT

4183
02:33:38,731 --> 02:33:40,300
LATER IN THE DAY, WE HAVE A

4184
02:33:40,300 --> 02:33:41,467
LITTLE BIT MORE TIME RATER IN

4185
02:33:41,467 --> 02:33:42,902
THE DAY, SO IF YOU THINK ABOUT

4186
02:33:42,902 --> 02:33:44,237
SOMETHING YOU WOULD LIKE TO

4187
02:33:44,237 --> 02:33:46,005
COMMENT ON OR ADD, JUST JOT IT

4188
02:33:46,005 --> 02:33:48,007
DOWN AND WE WILL BE HAPPY TO

4189
02:33:48,007 --> 02:33:49,342
RECEIVE IT LATER IN THE DAY, BUT

4190
02:33:49,342 --> 02:33:52,045
I'M GOING TO TURN IT BACK OVER

4191
02:33:52,045 --> 02:33:56,149
TO THE EXEC SEC OF ACWHR,

4192
02:33:56,149 --> 02:33:57,650
DR. VIF RAN OTA WANG FOR OUR

4193
02:33:57,650 --> 02:33:58,017
NEXT STEPS.

4194
02:33:58,017 --> 02:33:59,986
>> SO FIRST OF ALL I JUST
HAVE

4195
02:33:59,986 --> 02:34:02,388
TO SAY, I AM REALLY APPRECIATIVE

4196
02:34:02,388 --> 02:34:03,890
OF THE TREMENDOUS

4197
02:34:03,890 --> 02:34:05,491
PRESENTEDDATIONS THAT WE'VE HAD

4198
02:34:05,491 --> 02:34:06,492
THIS MORNING.

4199
02:34:06,492 --> 02:34:08,695
AND REALLY THE GREAT

4200
02:34:08,695 --> 02:34:08,995
DISCUSSIONS.

4201
02:34:08,995 --> 02:34:10,997
SO AT THIS TIME, WHAT I WOULD

4202
02:34:10,997 --> 02:34:15,168
LIKE IS IF ALL OF THE MEMBERS

4203
02:34:15,168 --> 02:34:16,669
COULD JOIN US ON CAMERA SO WE

4204
02:34:16,669 --> 02:34:18,538
COULD AT LEAST TAKE A VIRTUAL

4205
02:34:18,538 --> 02:34:19,973
PHOTO OF US ALL, AND THEN AFTER

4206
02:34:19,973 --> 02:34:24,577
THAT WE WILL TAKE A BREAK IF YOU

4207
02:34:24,577 --> 02:34:27,146
COULD BE BACK BY 12:30, WE WILL

4208
02:34:27,146 --> 02:34:28,881
START WITH OUR AFTERNOON

4209
02:34:28,881 --> 02:34:29,211
PRESENTATIONS AND DISCUSSION.

4210
02:34:29,211 --> 02:34:30,912
WELCOME BACK EVERYBODY, I

4211
02:34:30,912 --> 02:34:33,315
WOULD NOW LIKE TO CALL THE

4212
02:34:33,315 --> 02:34:38,787
MEETING TO ORDER AND INTRODUCE

4213
02:34:38,787 --> 02:34:40,522
DR. BELINDA SETO WHO WILL BE

4214
02:34:40,522 --> 02:34:42,124
MODERATING OUR PANEL ON DATA

4215
02:34:42,124 --> 02:34:46,228
SCIENCE AND WOMEN'S HEALTH.

4216
02:34:46,228 --> 02:34:49,631
THE INTRODUCTION I HAVE WILL NOT

4217
02:34:49,631 --> 02:34:52,134
DO JUSTICE TO THE DR. SET, BUT I

4218
02:34:52,134 --> 02:34:55,303
WILL DO MY BEST.

4219
02:34:55,303 --> 02:34:58,173
DR. SETO WAS APPOINTED TO THE

4220
02:34:58,173 --> 02:35:00,675
OFFICE OF DATA STRATEGY IN 2019.

4221
02:35:00,675 --> 02:35:03,311
HER AREAS OF OF AVAILABLE ARE IN

4222
02:35:03,311 --> 02:35:04,112
COMMON STANDARDS, COMMON

4223
02:35:04,112 --> 02:35:05,313
ELMETROPOLITANS AND REAL WORLD

4224
02:35:05,313 --> 02:35:05,547
DATA.

4225
02:35:05,547 --> 02:35:06,948
THE FORMER DEPUTY DIRECTOR OF

4226
02:35:06,948 --> 02:35:08,950
THE NATIONAL EYE INSTITUTE AND A

4227
02:35:08,950 --> 02:35:11,620
NATIONAL INSTITUTE OF BIOMEDICAL

4228
02:35:11,620 --> 02:35:14,189
IMAGING AND BIOENGINEERING, SHE

4229
02:35:14,189 --> 02:35:15,023
BRINGS ORGANIZATIONAL LEADERSHIP

4230
02:35:15,023 --> 02:35:16,658
EXPERIENCE AND SCIENTIFIC

4231
02:35:16,658 --> 02:35:18,026
KNOWLEDGE TO THE POSITION.

4232
02:35:18,026 --> 02:35:21,730
AFTER EARNING HER Ph.D. IN

4233
02:35:21,730 --> 02:35:24,032
BIOCHEMISTRY FROM FROM PURDUE

4234
02:35:24,032 --> 02:35:25,400
UNIVERSITY, DR. SETO COMPLETED

4235
02:35:25,400 --> 02:35:27,369
OR POST DOCTORAL FELLOWSHIP AT

4236
02:35:27,369 --> 02:35:28,537
THE NATIONAL HEART LUNG AND

4237
02:35:28,537 --> 02:35:29,437
BLOOD INSTITUTE.

4238
02:35:29,437 --> 02:35:31,206
SHE CONDUCKED RESEARCH ON

4239
02:35:31,206 --> 02:35:32,574
HEPATITIS B AND VACCINE

4240
02:35:32,574 --> 02:35:34,009
DEVELOPMENT AT THE FDA AS WELL.

4241
02:35:34,009 --> 02:35:35,844
SHE WAS A PROGRAM DIRECTOR IN

4242
02:35:35,844 --> 02:35:38,013
THE OFFICE OF RESEARCH AND

4243
02:35:38,013 --> 02:35:39,748
MINORITY HEALTH, WHERE SHE LED

4244
02:35:39,748 --> 02:35:42,384
SEMINOLE STUDIES ON INFANT

4245
02:35:42,384 --> 02:35:43,418
MORTALITY AND MENOPAUSORRITY

4246
02:35:43,418 --> 02:35:44,819
YOUTH BEHAVIOR HEALTH STUDIES.

4247
02:35:44,819 --> 02:35:46,988
AS DEPUTY DIRECTOR OF THE OFFICE

4248
02:35:46,988 --> 02:35:49,224
OF EXTRAMURAL RESEARCH, SHE ALSO

4249
02:35:49,224 --> 02:35:50,959
LED INITIATIVES OF DATABASE

4250
02:35:50,959 --> 02:35:52,727
MANAGEMENT, OPEN ACCESS TO NIH

4251
02:35:52,727 --> 02:35:55,330
FUNDING TRENDS AND DATA SHARING

4252
02:35:55,330 --> 02:35:55,697
POLICY.

4253
02:35:55,697 --> 02:35:58,433
HER VAST EXPERIENCE AND

4254
02:35:58,433 --> 02:36:00,602
DATABASED MANAGEMENT ANALYSIS

4255
02:36:00,602 --> 02:36:01,770
AND INTRAMURAL GRANT POLICIES

4256
02:36:01,770 --> 02:36:05,340
HAS LED TO APPOINT AMS BY THE

4257
02:36:05,340 --> 02:36:06,408
DIRECTOR AND THE NATIONAL --

4258
02:36:06,408 --> 02:36:09,010
EXCUSE ME TO THE SCIENTIFIC DATA

4259
02:36:09,010 --> 02:36:10,712
COUNCIL AT NIH IN THE DEPARTMENT

4260
02:36:10,712 --> 02:36:12,547
OF HEALTH AND HUMAN SERVICES

4261
02:36:12,547 --> 02:36:14,816
DATA COUNCIL.

4262
02:36:14,816 --> 02:36:15,483
WELCOME DR. SETO.

4263
02:36:15,483 --> 02:36:19,788
THANK YOU VERY MUCH FOR JOINING

4264
02:36:19,788 --> 02:36:20,855
TODAY'S PANEL.

4265
02:36:20,855 --> 02:36:22,624
>> THANK YOU VIVIAN FOR
THOSE

4266
02:36:22,624 --> 02:36:23,491
KIND INTRODUCTION.

4267
02:36:23,491 --> 02:36:27,896
IT IS MY DISTINCT PLEASURE TO

4268
02:36:27,896 --> 02:36:30,665
MODERATE THIS PANEL WITH REALLY

4269
02:36:30,665 --> 02:36:31,600
DISTINGUISHED SPEAKERS, I'M SO

4270
02:36:31,600 --> 02:36:33,001
LOOKING FORWARD TO IT I GO OVER

4271
02:36:33,001 --> 02:36:34,869
THE SLIDES AND I SAY I CAN'T

4272
02:36:34,869 --> 02:36:37,138
WAIT TO HEAR THE PRESENTATION.

4273
02:36:37,138 --> 02:36:41,509
I WE WILL DO EACH PANELIST WILL

4274
02:36:41,509 --> 02:36:45,046
DO A 15 MINUTE PRESENTATION AND

4275
02:36:45,046 --> 02:36:49,150
IF THE AUDIENCE WILL HOLD THE

4276
02:36:49,150 --> 02:36:49,751
QUESTIONS UNTIL ALL 3

4277
02:36:49,751 --> 02:36:51,253
PRESENTATIONS ARE DONE, AND WE

4278
02:36:51,253 --> 02:36:52,921
WILL -- I WILL ASK A COUPLE OF

4279
02:36:52,921 --> 02:36:54,889
QUESTIONS AND THEN WE WILL OPEN

4280
02:36:54,889 --> 02:36:58,793
TO THE AUDIENCE FOR DISCUSSION

4281
02:36:58,793 --> 02:37:00,762
AND IF THAT IS OKAY VIVIAN, I

4282
02:37:00,762 --> 02:37:02,697
WILL GO AHEAD AND INTRODUCE THE

4283
02:37:02,697 --> 02:37:05,767
FIRST SPEAKER DR. MOORE.

4284
02:37:05,767 --> 02:37:06,434
GREAT.

4285
02:37:06,434 --> 02:37:07,135
THANK YOU.

4286
02:37:07,135 --> 02:37:08,403
DR. MOORE JASON MOORE IS THE

4287
02:37:08,403 --> 02:37:12,040
CHAIR OF THE DEPARTMENT OF

4288
02:37:12,040 --> 02:37:18,046
COMPUTATIONAL MEDICINE AT CEDAR

4289
02:37:18,046 --> 02:37:19,581
SINAI MEDICAL CENTER WHERE HE

4290
02:37:19,581 --> 02:37:22,384
SERVES AS DIRECTOR FOR

4291
02:37:22,384 --> 02:37:23,385
ARTIFICIAL INTELLIGENCE RESEARCH

4292
02:37:23,385 --> 02:37:25,520
AND EDUCATION, HE LEADS AN

4293
02:37:25,520 --> 02:37:26,588
ACTIVE RESEARCH PROGRAM FOCUSED

4294
02:37:26,588 --> 02:37:28,189
ON THE DEVELOPMENT AND

4295
02:37:28,189 --> 02:37:29,724
APPLICATION OF ARTIFICIAL

4296
02:37:29,724 --> 02:37:31,826
INTELLIGENCE ALGORITHMS FOR THE

4297
02:37:31,826 --> 02:37:34,863
ANALYSIS OF BIOMEDICAL DATA.

4298
02:37:34,863 --> 02:37:38,466
RECENT WORK FOCUSES ON METHODS

4299
02:37:38,466 --> 02:37:39,768
FOR AUTOMATED MACHINE LEARNING

4300
02:37:39,768 --> 02:37:43,772
WITH A GOAL OF DEMOCRATIZING AI

4301
02:37:43,772 --> 02:37:44,472
IN HEALTHCARE.

4302
02:37:44,472 --> 02:37:47,342
HE IS AN ELECTIVE FELLOW OF THE

4303
02:37:47,342 --> 02:37:51,112
AMERICAN COLLEGE OF MEDICAL

4304
02:37:51,112 --> 02:37:52,147
INFORMATICS, THE INTERNATIONAL

4305
02:37:52,147 --> 02:37:54,249
ACADEMY OF HEALTH SCIENCES

4306
02:37:54,249 --> 02:37:58,253
INFORMATICS, AND THE AMERICAN

4307
02:37:58,253 --> 02:37:59,554
STATISTICAL ASSOCIATION.

4308
02:37:59,554 --> 02:38:03,992
SHE'S EDITOR IN CHIEF OF THE

4309
02:38:03,992 --> 02:38:04,492
JOURNAL BIODATA MINING.

4310
02:38:04,492 --> 02:38:08,496
THE FLOOR AND THE MIC IS YOURS,

4311
02:38:08,496 --> 02:38:08,763
DR. MOORE.

4312
02:38:08,763 --> 02:38:09,064
>> GREAT.

4313
02:38:09,064 --> 02:38:12,701
THANK YOU SO MUCH AND IT'S

4314
02:38:12,701 --> 02:38:14,402
REALLY WONDERFUL TO BE WITH ALL

4315
02:38:14,402 --> 02:38:16,738
OF YOU TODAY FOR THIS PANEL.

4316
02:38:16,738 --> 02:38:18,139
I'M REALLY LOOKING FORWARD TO

4317
02:38:18,139 --> 02:38:20,809
IT, AS YOU HEARD I'M AN AI

4318
02:38:20,809 --> 02:38:21,843
METHODOLOGIST, I DEVELOPED AI

4319
02:38:21,843 --> 02:38:23,111
METHODS AND HAVE MY ENTIRE

4320
02:38:23,111 --> 02:38:25,480
CAREER AND I WILL TOUCH A LITTLE

4321
02:38:25,480 --> 02:38:28,717
BIT OF THAT ON THE END HAPPENED

4322
02:38:28,717 --> 02:38:29,818
OF MY PRESENTATION, WHAT I WANT

4323
02:38:29,818 --> 02:38:32,320
TO DO IS COMMUNICATE THE

4324
02:38:32,320 --> 02:38:34,155
CHALLENGES WE FACE WORKING WITH

4325
02:38:34,155 --> 02:38:35,357
DID THEA ESPECIALLY AROUND THIS

4326
02:38:35,357 --> 02:38:36,958
NEW ERA OF AI.

4327
02:38:36,958 --> 02:38:40,362
AND LET ME JUST SAY THAT IF YOU

4328
02:38:40,362 --> 02:38:42,297
SEE AN OPPORTUNITY TO DLABERATE

4329
02:38:42,297 --> 02:38:44,366
OR IF THERE'S SOME WAY I CAN

4330
02:38:44,366 --> 02:38:45,433
HELP YOU PLEASE FEEL FREE TO

4331
02:38:45,433 --> 02:38:46,134
REACH OUT.

4332
02:38:46,134 --> 02:38:50,205
MY E-MAIL ADDRESS IS HERE ON THE

4333
02:38:50,205 --> 02:38:50,405
SLIDE.

4334
02:38:50,405 --> 02:38:52,640
SO LET ME START WITH THIS

4335
02:38:52,640 --> 02:38:54,342
CONCEPT OF LEARNING HEALTH

4336
02:38:54,342 --> 02:38:56,411
SYSTEM, I WORK AT A BIG HOSPITAL

4337
02:38:56,411 --> 02:38:59,147
HERE IN LA, AND YOU KNOW WE DO

4338
02:38:59,147 --> 02:39:01,149
RESEARCH AND WE HOPE THAT THAT

4339
02:39:01,149 --> 02:39:02,417
RESEARCH WILL TURN INTO EVIDENCE

4340
02:39:02,417 --> 02:39:05,153
AND THAT EVIDENCE WILL LEAD TO

4341
02:39:05,153 --> 02:39:07,956
CARE AND GOOD CARE WILL LEAD TO

4342
02:39:07,956 --> 02:39:10,959
AN IMPROVED PATIENT EXPERIENCE,

4343
02:39:10,959 --> 02:39:12,160
BUT UNFORTUNATELY ALONG THERE

4344
02:39:12,160 --> 02:39:13,862
PATH, THERE'S A LOT OF SCIENCE

4345
02:39:13,862 --> 02:39:16,297
AND RESEARCH THAT IS PUBLISHED

4346
02:39:16,297 --> 02:39:17,699
BUT NEVER FINDS ITS WAY INTO

4347
02:39:17,699 --> 02:39:18,833
EVIDENT, THERE'S A LOT OF

4348
02:39:18,833 --> 02:39:20,101
EVIDENCE THAT NEVER FINDS ITS

4349
02:39:20,101 --> 02:39:22,670
WAY INTO CARE AND THERE'S A LOT

4350
02:39:22,670 --> 02:39:23,972
OF CARE STRATEGIES THAT DON'T

4351
02:39:23,972 --> 02:39:27,575
NECESSARILY IMPROVE THE IDEA OF

4352
02:39:27,575 --> 02:39:28,743
PATIENT EXPERIENCE, SO THE IDEA

4353
02:39:28,743 --> 02:39:31,946
IS TO TIGHTEN THIS UP SO THAT WE

4354
02:39:31,946 --> 02:39:33,415
HAVE AN EFFICIENT PIPELINE THAT

4355
02:39:33,415 --> 02:39:34,749
LEAD TO IMPROVE PATIENT

4356
02:39:34,749 --> 02:39:35,316
STRATEGIES AND EXPERIENCES.

4357
02:39:35,316 --> 02:39:37,152
THIS IS A DEFINITION OF AN

4358
02:39:37,152 --> 02:39:38,820
LEARNING HEALTH SYSTEM FROM THE

4359
02:39:38,820 --> 02:39:39,754
INSTITUTE OF MEDICINE 10 YEARS

4360
02:39:39,754 --> 02:39:42,056
AGO, A SYSTEM IN WHICH SCIENCE,

4361
02:39:42,056 --> 02:39:43,925
INFORMATICS AND CULTURE ALIGN

4362
02:39:43,925 --> 02:39:45,994
FOR CONTINUOUS IMPROVEMENT OF

4363
02:39:45,994 --> 02:39:46,528
THE HEALTHCARE DELIVERY

4364
02:39:46,528 --> 02:39:49,464
EXPERIENCE AND THIS IS THE IDEA

4365
02:39:49,464 --> 02:39:52,600
AND I HIGHLIGHTED INFORMATICS

4366
02:39:52,600 --> 02:39:53,535
BECAUSE COMPUTATION,

4367
02:39:53,535 --> 02:39:54,903
INFORMATICS, DATA SCIENCE,

4368
02:39:54,903 --> 02:39:57,772
STATISTICS ALL PLAY AN IMPORTANT

4369
02:39:57,772 --> 02:40:00,408
ROLE IN GLEANING DATA SETS OF SO

4370
02:40:00,408 --> 02:40:01,743
WE CAN TIGHTEN UP THIS PIPELINE.

4371
02:40:01,743 --> 02:40:02,944
THIS IS A PIPELINE OF WHAT WE

4372
02:40:02,944 --> 02:40:05,447
WANT TO TALK ABOUT, AROUND THE

4373
02:40:05,447 --> 02:40:06,047
CHALLENGES OF LEARN FREE

4374
02:40:06,047 --> 02:40:07,415
RADICALS GENERATED DATA IN A

4375
02:40:07,415 --> 02:40:09,884
LEARNING HEALTH SYSTEM

4376
02:40:09,884 --> 02:40:10,785
ENVIRONMENT.

4377
02:40:10,785 --> 02:40:13,521
DATA ARE EXPENSIVE AND THEY ARE

4378
02:40:13,521 --> 02:40:14,923
OFTEN STATIC, MESSY, DIFFICULT

4379
02:40:14,923 --> 02:40:16,291
TO INTEGRATE, THEY'RE PRIVATE,

4380
02:40:16,291 --> 02:40:17,158
DIFFICULT TO ANALYZE AND

4381
02:40:17,158 --> 02:40:19,594
DIFFICULT TO PUT INTO PRACTICE

4382
02:40:19,594 --> 02:40:19,994
OR OPERATIONALIZE.

4383
02:40:19,994 --> 02:40:22,931
SO I WILL TOUCH ON EACH OF

4384
02:40:22,931 --> 02:40:23,498
THESE.

4385
02:40:23,498 --> 02:40:25,133
IT'S AN EXCITING TIME OF COURSE

4386
02:40:25,133 --> 02:40:26,868
BECAUSE WE CAN MEASURE LOTS OF

4387
02:40:26,868 --> 02:40:28,870
DIFFERENT KINDS OF DATA ABOUT

4388
02:40:28,870 --> 02:40:31,906
HUMAN SUBJECTS RANGING FROM

4389
02:40:31,906 --> 02:40:34,108
OMICS DATA TO ELECTRONIC HEALTH

4390
02:40:34,108 --> 02:40:35,810
RECORD CLINICAL DATA, IMAGING

4391
02:40:35,810 --> 02:40:39,113
DATA AND MOBILE HEALTH DATA FOR

4392
02:40:39,113 --> 02:40:41,516
EXAMPLE, BUT AS YOU KNOW,

4393
02:40:41,516 --> 02:40:42,383
COLLECTING ALL THESE DIFFERENT

4394
02:40:42,383 --> 02:40:46,454
KINDS OF DATA ARE EXPENSIVE AND

4395
02:40:46,454 --> 02:40:47,255
TIME CONSUMING AND IT'S

4396
02:40:47,255 --> 02:40:48,656
IMPORTANT ONCE IN A WHILE TO

4397
02:40:48,656 --> 02:40:50,492
STEP BACK AND APPRECIATE AND

4398
02:40:50,492 --> 02:40:53,695
VALUE JUST HOW EXPENSIVE AND

4399
02:40:53,695 --> 02:40:55,363
TIME CONSUMING DATA ARE TO

4400
02:40:55,363 --> 02:40:55,697
COLLECT.

4401
02:40:55,697 --> 02:40:57,065
ONE OF THE BIG ISSUES WE DON'T

4402
02:40:57,065 --> 02:40:58,233
THINK ABOUT A LOT BUT SHOULD

4403
02:40:58,233 --> 02:41:00,835
THINK ABOUT MORE IS THAT DATA

4404
02:41:00,835 --> 02:41:03,471
ARE OFTEN STATIC, THE KINDS OF

4405
02:41:03,471 --> 02:41:05,006
THINGS WE CARE ABOUT LIKE THE

4406
02:41:05,006 --> 02:41:07,408
KINDS OF THINGS WE CAN MONITOR

4407
02:41:07,408 --> 02:41:09,477
WITH MOBILE HEALTH APPLICATIONS,

4408
02:41:09,477 --> 02:41:11,679
SMART PHONE ANDS SMART WATCHES

4409
02:41:11,679 --> 02:41:13,481
THESE ARE CONTINUOUS

4410
02:41:13,481 --> 02:41:15,517
MEASUREMENTS HEART RATE

4411
02:41:15,517 --> 02:41:17,185
VARIABILITY, BLOOD PRESSURE

4412
02:41:17,185 --> 02:41:17,719
AVAILABILITY, CHOLESTEROL

4413
02:41:17,719 --> 02:41:19,254
MEASURES, ALL OF THESE ARE

4414
02:41:19,254 --> 02:41:21,523
DYNAMIC AND TIME IN SPACE AND

4415
02:41:21,523 --> 02:41:24,025
CHANGE OVER OUR LIFETIME, SECOND

4416
02:41:24,025 --> 02:41:25,894
TO SECOND, MINUTE TO MINUTE,

4417
02:41:25,894 --> 02:41:27,228
YEAR TO YEAR, ET CETERA AND WHAT

4418
02:41:27,228 --> 02:41:30,565
DO WE DO, WE VERY OFTEN TAKE A

4419
02:41:30,565 --> 02:41:31,499
SINGLE MEMBER MEASUREMENT FROM

4420
02:41:31,499 --> 02:41:33,201
THIS COMPLEK DYNAMIC TRAJECTORY

4421
02:41:33,201 --> 02:41:36,237
AND WE CALL THAT A PATIENT'S

4422
02:41:36,237 --> 02:41:38,873
MEASUREMENT, SO THIS I WOULD SAY

4423
02:41:38,873 --> 02:41:39,474
INACCURATELY CAPTURES WHAT'S

4424
02:41:39,474 --> 02:41:40,408
GOING ON IN A PATIENT AND

4425
02:41:40,408 --> 02:41:42,343
SOMETHING THAT WE SHOULD THINK

4426
02:41:42,343 --> 02:41:42,944
ABOUT MORE.

4427
02:41:42,944 --> 02:41:44,345
OF COURSE BACK TO THE FIRST

4428
02:41:44,345 --> 02:41:47,115
SLIDE DATA IS EXPENSIVE AND

4429
02:41:47,115 --> 02:41:49,651
COLLECTING TIME SERIES DATA IS

4430
02:41:49,651 --> 02:41:51,219
EXPENSIVE AND PRESENTS A WHOLE

4431
02:41:51,219 --> 02:41:56,891
BUNCH OF OTHER CHALLENGES. 

4432
02:41:56,891 --> 02:41:58,893
DATA ARE MESSY, OMICS DATA CAN

4433
02:41:58,893 --> 02:42:00,295
BE MESSY, CLINICAL DATA FROM THE

4434
02:42:00,295 --> 02:42:02,030
ELECTRONIC HEALTH RECORD IS

4435
02:42:02,030 --> 02:42:03,631
ESPECIALLY MESSY, THIS IS A

4436
02:42:03,631 --> 02:42:06,734
SLIDE I LOVE AS A FIGURE FROM A

4437
02:42:06,734 --> 02:42:08,469
PAPER, NATURE PAPER FROM 2018,

4438
02:42:08,469 --> 02:42:13,141
ON LOOKING AT EHR DATEDDA FROM

4439
02:42:13,141 --> 02:42:13,741
AML PATIENTS.

4440
02:42:13,741 --> 02:42:15,543
AND THE COLUMNS IN THE HEAT MAP

4441
02:42:15,543 --> 02:42:18,079
ARE PATIENTS AND EACH ROW IS A

4442
02:42:18,079 --> 02:42:19,881
DIFFERENT CLINICAL VARIABLE FROM

4443
02:42:19,881 --> 02:42:20,815
THE ELECTRONIC HEALTH RECORD

4444
02:42:20,815 --> 02:42:25,286
THAT THEY LOOKED AT.

4445
02:42:25,286 --> 02:42:26,588
AND THE LIGHT GRAY SQUARES IN

4446
02:42:26,588 --> 02:42:28,690
THE HEAT MAP ARE MISSING DATA SO

4447
02:42:28,690 --> 02:42:31,392
YOU CAN SEE EVERY PATIENT HAS

4448
02:42:31,392 --> 02:42:33,094
QUITE A BIT OF MISSING DATA

4449
02:42:33,094 --> 02:42:34,762
ACROSS ALL THESE VARIABLES AND

4450
02:42:34,762 --> 02:42:36,331
EACH VARIABLE IN AND OF ITSELF

4451
02:42:36,331 --> 02:42:38,299
HAS QUIT A BIT OF MISSING DATA

4452
02:42:38,299 --> 02:42:39,734
SO BIG QUESTION IS WHAT DO YOU

4453
02:42:39,734 --> 02:42:42,470
DO WITH THAT, WHAT DO YOU WITH

4454
02:42:42,470 --> 02:42:44,238
THE OUTLIERS OF THE DATA THAT'S

4455
02:42:44,238 --> 02:42:47,108
PRESENT AND WHAT DO YOU DO WITH

4456
02:42:47,108 --> 02:42:48,276
ALL THE MISSING DATA?

4457
02:42:48,276 --> 02:42:50,445
DO YOU THROW IT AWAY?

4458
02:42:50,445 --> 02:42:51,479
DO YOU IMPUTE IT?

4459
02:42:51,479 --> 02:42:53,214
THESE ARE THE QUESTIONS WE

4460
02:42:53,214 --> 02:42:54,782
STRUGGLE WITH IN THE DAILY BASIS

4461
02:42:54,782 --> 02:42:55,817
THEA CLEANING AND QUALITY

4462
02:42:55,817 --> 02:42:59,087
CONTROL PHASE OF ANY DATA

4463
02:42:59,087 --> 02:42:59,420
SCIENCE STUDY.

4464
02:42:59,420 --> 02:43:00,822
DATA ARE DIFFICULT TO INTEGRATE

4465
02:43:00,822 --> 02:43:02,357
AND 1 OF THE FIRST THINGS WE

4466
02:43:02,357 --> 02:43:03,324
THINK ABOUT ESPECIALLY

4467
02:43:03,324 --> 02:43:04,926
WELCOMERRING WITH CLINICAL DATA

4468
02:43:04,926 --> 02:43:05,927
IS DEFINING THE PHENOTYPE THAT

4469
02:43:05,927 --> 02:43:07,829
WE'RE INTERESTED IN, THAT COULD

4470
02:43:07,829 --> 02:43:12,166
BE A WOMEN'S HEALTH ISSUE, AND

4471
02:43:12,166 --> 02:43:13,601
DISEASE, A CONDITION, AND

4472
02:43:13,601 --> 02:43:15,770
ESPECIALLY IN CLINICAL DATA

4473
02:43:15,770 --> 02:43:17,639
PHENOTYPES OFTEN COME FROM ICD

4474
02:43:17,639 --> 02:43:20,174
BILLING CODES AND BILLING CODES

4475
02:43:20,174 --> 02:43:21,843
ARE THERE FOR BILLS PURPOSES AND

4476
02:43:21,843 --> 02:43:23,378
NOT NECESSARILY TO ACCURATELY

4477
02:43:23,378 --> 02:43:24,746
DEFINE A FEIGNIE TYPE FOR A

4478
02:43:24,746 --> 02:43:27,315
PATIENT, AND SO WE NEED LOTS OF

4479
02:43:27,315 --> 02:43:30,551
DIFFERENT KINDS OF DATA DISP WE

4480
02:43:30,551 --> 02:43:31,719
NEED LABORATORY TESTS,

4481
02:43:31,719 --> 02:43:32,787
MEDICATIONS, WE NEED OTHER

4482
02:43:32,787 --> 02:43:34,455
CLINICAL MEASURES, WE COULD HAVE

4483
02:43:34,455 --> 02:43:38,126
GENETIC MEASURES HERE, WE COULD

4484
02:43:38,126 --> 02:43:39,527
HAVE ENVIRONMENTAL MEASURES THAT

4485
02:43:39,527 --> 02:43:40,628
TOGETHER ACCURATELY DEFINE A

4486
02:43:40,628 --> 02:43:42,230
PHENOTYPE FOR A PATIENT AND SO

4487
02:43:42,230 --> 02:43:45,366
THAT REQUIRES DATA INTEGRATION

4488
02:43:45,366 --> 02:43:47,802
AND OF COURSE EACH HELT SYSTEM

4489
02:43:47,802 --> 02:43:49,303
COLLECTS DATA IN A DIFFERENT

4490
02:43:49,303 --> 02:43:51,205
WAY, WE USE DIFFERENT

4491
02:43:51,205 --> 02:43:53,174
INSTRUMENTS, WE USE DIFFERENT

4492
02:43:53,174 --> 02:43:54,308
LABORATORY TESTS, DIFFERENT

4493
02:43:54,308 --> 02:43:55,410
ASSAYS FROM DIFFERENT VENDORS

4494
02:43:55,410 --> 02:43:57,979
AND THAT CREATE AS I LOT OF

4495
02:43:57,979 --> 02:43:58,913
HETEROGENEITY FROM SITE TO SITE

4496
02:43:58,913 --> 02:44:00,648
IF WE'RE TRYING TO INTEGRATE

4497
02:44:00,648 --> 02:44:01,482
DATA FROM DIFFERENT SOURCES AND

4498
02:44:01,482 --> 02:44:05,920
SO WE NEED TO THINK ABOUT COMMON

4499
02:44:05,920 --> 02:44:08,456
DATA MODELS, THAT ARE DATA

4500
02:44:08,456 --> 02:44:10,858
STANDARDS CAN MAP OUR DATA TO SO

4501
02:44:10,858 --> 02:44:15,229
THAT WE AT CEDAR SINAI, THIS IS

4502
02:44:15,229 --> 02:44:16,964
A PATIENT'S GLUCOSE LEVEL OR A1C

4503
02:44:16,964 --> 02:44:19,033
LEVEL OR THIS IS THE MEDICATION

4504
02:44:19,033 --> 02:44:22,103
THEY'RE TAKING THAT IT'S EXACTLY

4505
02:44:22,103 --> 02:44:24,372
THE SAME AS THOSE THINGS AT YOUR

4506
02:44:24,372 --> 02:44:26,774
INSTITUTION AND ONCE WE MAP IT

4507
02:44:26,774 --> 02:44:28,710
TO ACCOMMODATE A MODEL, THEN WE

4508
02:44:28,710 --> 02:44:30,845
CAN START TO EITHER INTEGRATE

4509
02:44:30,845 --> 02:44:32,914
DATA DIRECTLY OR DO A FEDERATED

4510
02:44:32,914 --> 02:44:34,882
ANALYSIS OF THE DATA AND

4511
02:44:34,882 --> 02:44:35,817
DIFFERENT SITES AND INTEGRATE

4512
02:44:35,817 --> 02:44:36,984
THE RESULTS AND AS YOU CAN

4513
02:44:36,984 --> 02:44:39,320
IMAGINE, THIS IS A TIME

4514
02:44:39,320 --> 02:44:40,922
CONSUMING DIFFICULT PROCESS BUT

4515
02:44:40,922 --> 02:44:43,424
NONETHELESS A VERY IMPORTANT

4516
02:44:43,424 --> 02:44:44,726
PROCESS, FOR PULLING DATA

4517
02:44:44,726 --> 02:44:48,029
TOGETHER TO DO A BETTER

4518
02:44:48,029 --> 02:44:49,397
ANALYSIS; NOW OF COURSE 1 OF THE

4519
02:44:49,397 --> 02:44:51,265
THINGS WE THINK A LOT ABOUT IS

4520
02:44:51,265 --> 02:44:54,602
THE PRIVACY OF OUR PATIENTS, OUR

4521
02:44:54,602 --> 02:44:55,803
HUMAN SUBJECTS FOR THE RESEARCH

4522
02:44:55,803 --> 02:44:57,305
DATA THAT WE COLLECT, THE

4523
02:44:57,305 --> 02:45:00,575
CLINICAL DATA WE COLLECT, AND

4524
02:45:00,575 --> 02:45:02,210
THERE ARE DIFFERENT WAYS TO DEAL

4525
02:45:02,210 --> 02:45:06,981
WITH THAT, OF COURSE, 1 APPROACH

4526
02:45:06,981 --> 02:45:08,816
IS DEIDENTIFY THE DATA, SHARE

4527
02:45:08,816 --> 02:45:10,885
THE DATA FROM MULTIPLE SITES,

4528
02:45:10,885 --> 02:45:14,188
AND DO A CENTRALIZED ANALYSIS OF

4529
02:45:14,188 --> 02:45:14,922
THAT DATA.

4530
02:45:14,922 --> 02:45:15,757
SO YOU COULD CLEAN THE DAILY

4531
02:45:15,757 --> 02:45:18,459
BASIS THEA, MAP IT TO A COMMON

4532
02:45:18,459 --> 02:45:20,027
DATA MODEL, DEIDENTIFY IT AND

4533
02:45:20,027 --> 02:45:22,130
SHARE IT IN A CENTRALIZED MANNER

4534
02:45:22,130 --> 02:45:23,664
AND THERE ARE PLENTY OF NATIONAL

4535
02:45:23,664 --> 02:45:26,100
STUDIES THAT DO THIS, THE

4536
02:45:26,100 --> 02:45:27,268
ADVANTAGES, THE DATA'S ALL IN 1

4537
02:45:27,268 --> 02:45:29,704
PLACE AND YOU CAN DO 1

4538
02:45:29,704 --> 02:45:30,438
INDGREATED ANALYSIS, THE DOWN

4539
02:45:30,438 --> 02:45:32,740
SIDE OF COURSE IS THAT A

4540
02:45:32,740 --> 02:45:34,342
HOSPITAL SENDING CLINICAL DATA

4541
02:45:34,342 --> 02:45:35,743
TO A CENTRALIZED SITE LOOSES

4542
02:45:35,743 --> 02:45:38,813
CONTROL IN THOSE DATA COULD BE

4543
02:45:38,813 --> 02:45:40,615
COMPROMISED AND EVEN THOUGH THE

4544
02:45:40,615 --> 02:45:42,550
DATA IS DEIDENTIFIED, THERE IS

4545
02:45:42,550 --> 02:45:44,986
STILL WAYS TO IDENTIFY DATA FOR

4546
02:45:44,986 --> 02:45:47,054
A BAD ACTOR WHO'S MOTIVATED TO

4547
02:45:47,054 --> 02:45:47,755
DO SO.

4548
02:45:47,755 --> 02:45:50,324
SO THERE ARE SOME RISKS WITH

4549
02:45:50,324 --> 02:45:51,492
CENTRALIZED ANALYSIS.

4550
02:45:51,492 --> 02:45:52,593
THE OTHER APPROACH IS, THIS IS

4551
02:45:52,593 --> 02:45:54,595
THE APPROACH THAT I PERSONALLY

4552
02:45:54,595 --> 02:45:58,299
FAVOR IS THE FEDERATED APPROACH

4553
02:45:58,299 --> 02:46:00,468
WHERE AT SEKDAR SINAI, OUR DATA

4554
02:46:00,468 --> 02:46:02,170
STAYS AT OUR OWN INSTITUTION, WE

4555
02:46:02,170 --> 02:46:04,005
ANALYZE THE DATA HERE, YOU

4556
02:46:04,005 --> 02:46:06,073
ANALYZE YOUR DATA AT YOUR

4557
02:46:06,073 --> 02:46:06,941
INSTITUTION BEHIND YOUR SECURE

4558
02:46:06,941 --> 02:46:08,843
FIRE WALL AND THEN WE SHARE

4559
02:46:08,843 --> 02:46:10,144
MODELS AND GLEAN INSIGHTS FROM

4560
02:46:10,144 --> 02:46:10,978
THE MODELS THEMSELVES AND THERE

4561
02:46:10,978 --> 02:46:14,415
ARE WAYS FOR EXAMPLE WITH

4562
02:46:14,415 --> 02:46:17,118
PARAMETRIC STAT IFORTICICAL

4563
02:46:17,118 --> 02:46:19,687
ANALYSIS, LIKE LENOIRIAR OR

4564
02:46:19,687 --> 02:46:21,756
STATISTICAL AGGRESSION, CAN YOU

4565
02:46:21,756 --> 02:46:22,723
COMBINE THE STATISTICS THAT COME

4566
02:46:22,723 --> 02:46:24,559
OUT OF THESE APPROACHES WITHOUT

4567
02:46:24,559 --> 02:46:25,893
LOSING INFORMATION AND DO

4568
02:46:25,893 --> 02:46:29,697
INFERENCE AND GAIN MORE POWER BY

4569
02:46:29,697 --> 02:46:31,232
DOING A FEDERATED ANALYSIS.

4570
02:46:31,232 --> 02:46:33,968
SO THINGS ARE -- THERE ARE OTHER

4571
02:46:33,968 --> 02:46:35,469
STRATEGIES AS WELL, LIKE

4572
02:46:35,469 --> 02:46:36,771
SYNTHETIC DATA THAT CAN BE

4573
02:46:36,771 --> 02:46:37,839
GENERATED BUT THIS IS ALSO

4574
02:46:37,839 --> 02:46:41,209
SOMETHING WE NEED TO THINK ABOUT

4575
02:46:41,209 --> 02:46:45,112
AS WE WANT TO DO STUDIES ACROSS

4576
02:46:45,112 --> 02:46:45,713
MULTIPLE SITES.

4577
02:46:45,713 --> 02:46:48,149
DATA ARE DIFFICULT TO ANALYZE,

4578
02:46:48,149 --> 02:46:53,087
I'M -- I APPROACH HUMAN HEALTH

4579
02:46:53,087 --> 02:46:55,089
AS IF IT'S A COMPLEX ADAPTIVE

4580
02:46:55,089 --> 02:46:56,357
SYSTEM AND THAT'S WHAT THIS

4581
02:46:56,357 --> 02:46:57,792
SLIDE IS SHOWINGA THE BOTTOM, WE

4582
02:46:57,792 --> 02:47:00,428
HAVE ALL OF OUR BIOMARKERS, MANY

4583
02:47:00,428 --> 02:47:01,596
DIFFERENT INDIVIDUAL FACTORS

4584
02:47:01,596 --> 02:47:04,899
THAT WE CAN ANALYZE, THIS COULD

4585
02:47:04,899 --> 02:47:08,469
BE GENETIC MEASURES, PROTEIN

4586
02:47:08,469 --> 02:47:09,203
MEASURES, METABOLOMIC,

4587
02:47:09,203 --> 02:47:09,837
ENVIRONMENT, CLINICAL MEASURES,

4588
02:47:09,837 --> 02:47:12,273
SO THESE ARE ALL THE INDIVIDUAL

4589
02:47:12,273 --> 02:47:14,342
PIECES AND PARTS OF A COMPLEX

4590
02:47:14,342 --> 02:47:17,378
SYSTEM LIKE A PARTICULAR MEASURE

4591
02:47:17,378 --> 02:47:19,580
OF WOMEN'S HEALTH, THOSE

4592
02:47:19,580 --> 02:47:20,448
INDIVIDUAL COMPONENTS ORGANIZED

4593
02:47:20,448 --> 02:47:22,016
THEMSELVES PERHAPS IN THE

4594
02:47:22,016 --> 02:47:23,985
PATHWAYS, AND AT A HIGHER LEVEL

4595
02:47:23,985 --> 02:47:25,720
INTO CONTROL STRUCTURES AND

4596
02:47:25,720 --> 02:47:26,754
THOSE CONTROL STRUCTURES

4597
02:47:26,754 --> 02:47:28,022
INTERACT TO ULTIMATELY DETERMINE

4598
02:47:28,022 --> 02:47:28,856
A HEALTH OUTCOME AND THE POINT

4599
02:47:28,856 --> 02:47:32,560
OF THIS SLIDE IS TO SAY THAT

4600
02:47:32,560 --> 02:47:35,363
OFTEN WHAT WE DO IS WE TAKE A

4601
02:47:35,363 --> 02:47:36,998
SINGLE BIOMARKER OUT OF THIS

4602
02:47:36,998 --> 02:47:38,466
COMPLEX PICTURE, LIKE WHEN YOU

4603
02:47:38,466 --> 02:47:39,967
DO A GENOME WIDE ASSOCIATION

4604
02:47:39,967 --> 02:47:42,270
STUDY FOR GENETIC ASSOCIATIONS,

4605
02:47:42,270 --> 02:47:44,805
YOU TAKE A SINGLE NUCLEOTIDE

4606
02:47:44,805 --> 02:47:47,441
POLYMORPHISM OUT OF THIS COMPLEX

4607
02:47:47,441 --> 02:47:48,676
PICTURE AND WHETHER IT'S

4608
02:47:48,676 --> 02:47:50,144
ASSOCIATE WIDE A CLINICAL END

4609
02:47:50,144 --> 02:47:51,679
POINT AROUND SAY WOMEN'S HEALTH.

4610
02:47:51,679 --> 02:47:53,114
THAT IGNORES ALL OF THESE

4611
02:47:53,114 --> 02:47:55,516
INTERACTIONS, ALL OF THIS

4612
02:47:55,516 --> 02:47:57,151
COMPLEXITY, AND SO THIS IS 1 OF

4613
02:47:57,151 --> 02:47:58,686
THE REASONS DATA ARE DIFFICULT

4614
02:47:58,686 --> 02:48:00,187
TO ANALYZE IS THAT THE PATTERNS

4615
02:48:00,187 --> 02:48:02,556
THAT WE'RE LOOKING FOR ARE

4616
02:48:02,556 --> 02:48:04,926
COMPLEX AND YOU HAVE TO

4617
02:48:04,926 --> 02:48:05,993
UNDERSTAND AND EMBRACE THIS

4618
02:48:05,993 --> 02:48:07,895
COMPLEXITY TO DO A GOOD JOB WITH

4619
02:48:07,895 --> 02:48:09,397
ANALYSIS AND THIS IS 1 OF THE

4620
02:48:09,397 --> 02:48:10,998
AREAS WHERE AI I THINK HAS AN

4621
02:48:10,998 --> 02:48:13,200
IMPORTANT ROLE TO PLAY BECAUSE

4622
02:48:13,200 --> 02:48:15,036
AI AND MACHINE LEARNING ARE

4623
02:48:15,036 --> 02:48:17,571
SPECIFICALLY DESIGNED TO LOOK AT

4624
02:48:17,571 --> 02:48:20,107
MANY FACTORS, BIOMARKERS

4625
02:48:20,107 --> 02:48:22,710
SIMULTANEOUSLY AND CONSIDER THE

4626
02:48:22,710 --> 02:48:23,477
COMPLEX NONINTERACTIONS BETWEEN

4627
02:48:23,477 --> 02:48:24,645
THOSE FACTORS AND YOU THROW IN

4628
02:48:24,645 --> 02:48:26,781
THE DYNAMIC AND IT IS THE TIME

4629
02:48:26,781 --> 02:48:28,282
DIMENSION AND YOU GET A WHOLE

4630
02:48:28,282 --> 02:48:29,216
OTHER LEVEL OF COMPLEXITY BUT

4631
02:48:29,216 --> 02:48:32,286
THIS IS WHAT WE NEED ON DO TO

4632
02:48:32,286 --> 02:48:33,888
FULLY UNDERSTAND THE

4633
02:48:33,888 --> 02:48:38,392
UNDERPINNINGS OF COMMON COMPLEX

4634
02:48:38,392 --> 02:48:38,659
DISEASES.

4635
02:48:38,659 --> 02:48:41,462
NOW ONCE WE CLEAN THE DATA AND

4636
02:48:41,462 --> 02:48:43,898
WE'VE MAP TODAY TO ACOMMON DATA

4637
02:48:43,898 --> 02:48:47,001
MODEL, WE INTEGRATED IT, WE'VE

4638
02:48:47,001 --> 02:48:49,203
DONE A CONFIDENT ANALYSIS, WE

4639
02:48:49,203 --> 02:48:50,972
KEPT THE DATA SECURE AND

4640
02:48:50,972 --> 02:48:52,306
PRIVATE, THE REAL CHALLENGE

4641
02:48:52,306 --> 02:48:54,308
BEGIN ANDS THAT'S HOW TO

4642
02:48:54,308 --> 02:48:56,277
OPERATIONALIZE IT, SO YOU HAVE A

4643
02:48:56,277 --> 02:48:58,079
MODEL THAT YOU TRUST AND YOU'VE

4644
02:48:58,079 --> 02:48:59,947
DONE ALL THE HARD WORK TO BUILD

4645
02:48:59,947 --> 02:49:05,519
A GOOD MODEL, THEN YOU HAVE TO

4646
02:49:05,519 --> 02:49:08,689
COMMUNICATE THAT THROUGH PEER

4647
02:49:08,689 --> 02:49:09,623
REVIEWED LITERATURE, THAT MODEL

4648
02:49:09,623 --> 02:49:11,959
NEEDS TO BE REPLICATED AND

4649
02:49:11,959 --> 02:49:12,693
VALIDATED AND INDEPENDENT DATA

4650
02:49:12,693 --> 02:49:16,197
SETS FOR IT TO BE BELIEVABLE,

4651
02:49:16,197 --> 02:49:17,932
AND SO THEN, THAT'S THE TOP

4652
02:49:17,932 --> 02:49:19,100
PART, THE PROCESS WE GO THROUGH

4653
02:49:19,100 --> 02:49:21,202
TO GO THROUGH THE PEER REVIEW

4654
02:49:21,202 --> 02:49:22,003
PROCESS TO CONVINCE OTHERS THAT

4655
02:49:22,003 --> 02:49:24,105
THIS IS A GOOD MODEL AND THAT

4656
02:49:24,105 --> 02:49:25,840
THEY SHOULD BE INTERESTED IN

4657
02:49:25,840 --> 02:49:27,708
DOING MORE WITH IT, BUT LET'S

4658
02:49:27,708 --> 02:49:29,844
SAY WE WANT TO DEPLOY IT IN THE

4659
02:49:29,844 --> 02:49:32,146
CLINIC, THIS OPENS THE DOOR TO

4660
02:49:32,146 --> 02:49:36,817
AN ENTIRE LENGTHY PROCESS, IS

4661
02:49:36,817 --> 02:49:37,685
THE MODEL GENERAL?

4662
02:49:37,685 --> 02:49:40,788
DOES IT TREAT ALL PEOPLE

4663
02:49:40,788 --> 02:49:41,222
EQUALLY?

4664
02:49:41,222 --> 02:49:41,756
IS IT SAFE?

4665
02:49:41,756 --> 02:49:43,657
DOES IT HAVE THE POTENTIA WILL

4666
02:49:43,657 --> 02:49:45,226
TO HARM PEOPLE?

4667
02:49:45,226 --> 02:49:47,995
IS IT EFFICIENT, IS IT ENERGY

4668
02:49:47,995 --> 02:49:49,730
EFFICIENT FOR EXAMPLE, DO WE

4669
02:49:49,730 --> 02:49:52,466
TRUST THE ALGORITHM, CAN WE LOOK

4670
02:49:52,466 --> 02:49:54,201
AT THE ALGORITHM AND THE MODEL

4671
02:49:54,201 --> 02:49:56,037
AND UNDERSTAND WHAT IT DOES AND

4672
02:49:56,037 --> 02:49:57,972
TRUST IT JUST AS WE TRUST A

4673
02:49:57,972 --> 02:49:59,807
COLLEAGUE WHEN WE GO AND ASK FOR

4674
02:49:59,807 --> 02:50:03,611
AN OPINION ABOUT A PATIENT.

4675
02:50:03,611 --> 02:50:07,148
WE INCREASE -- HEALTH SYSTEMS

4676
02:50:07,148 --> 02:50:07,982
ARE INCREASINGLY UNDER FINANCIAL

4677
02:50:07,982 --> 02:50:11,819
STRAIN AS THE POPULATION AGES

4678
02:50:11,819 --> 02:50:13,154
AND HEALTHCARE REIMBURSEMENT

4679
02:50:13,154 --> 02:50:15,289
MODELS CHANGE SO WA ALSO THINK

4680
02:50:15,289 --> 02:50:17,358
ABOUT RETURN ON INVESTMENT, DOES

4681
02:50:17,358 --> 02:50:18,959
THIS SAFE HOSPITAL RESOURCES,

4682
02:50:18,959 --> 02:50:20,594
DOES IT SAVE TIME AND MONEY,

4683
02:50:20,594 --> 02:50:22,463
DOES IT FREE UP CLINICIANS TO DO

4684
02:50:22,463 --> 02:50:23,431
OTHER THINGS, SO THIS IS

4685
02:50:23,431 --> 02:50:25,132
SOMETHING THAT WE THINK ABOUT.

4686
02:50:25,132 --> 02:50:27,234
AND THEN WE HAVE TO THINK ABOUT,

4687
02:50:27,234 --> 02:50:28,869
DECISION SUPPORT, SO YOU WANT TO

4688
02:50:28,869 --> 02:50:30,504
PUT A MODEL INTO THE CLINIC, HOW

4689
02:50:30,504 --> 02:50:32,406
IS THAT MODEL GOING TO FIT INTO

4690
02:50:32,406 --> 02:50:33,774
A CLINICIANS WORK FLOW, DO THEY

4691
02:50:33,774 --> 02:50:36,844
HAVE TIME TO EVEN THINK ABOUT

4692
02:50:36,844 --> 02:50:39,914
WHAT THE MODEL IS TELLING THEM

4693
02:50:39,914 --> 02:50:41,916
ABOUT A PATIENT AND ONCE YOU

4694
02:50:41,916 --> 02:50:43,217
DEPLOY A MODEL IN THE CLINIC,

4695
02:50:43,217 --> 02:50:46,087
YOU HAVE TO AUDIT IT REGULARLIER

4696
02:50:46,087 --> 02:50:47,388
FEW MONTHS OR 6 MONTHS YOU HAVE

4697
02:50:47,388 --> 02:50:49,957
TO DO AN ANALYSIS OF THE MODEL,

4698
02:50:49,957 --> 02:50:52,726
IS IT STILL A SAFE, EFFICIENT,

4699
02:50:52,726 --> 02:50:53,561
EFFECTIVE TRUSTWORTHY MODEL

4700
02:50:53,561 --> 02:50:55,696
BECAUSE THE DATA CAN DRIFT AND

4701
02:50:55,696 --> 02:50:58,299
CHANGE OVER TIME AND

4702
02:50:58,299 --> 02:50:59,233
INSTRUMENTATION CHANGES AND WHAT

4703
02:50:59,233 --> 02:51:01,602
MIGHT BE AN EFFECTIVE MODEL

4704
02:51:01,602 --> 02:51:05,005
TODAY  MIGHT BE LESS EFFECTIVE N

4705
02:51:05,005 --> 02:51:08,609
6 MONTHS AS DATA SHIFT AND

4706
02:51:08,609 --> 02:51:08,843
CHANGES.

4707
02:51:08,843 --> 02:51:10,010
AND THEN OF COURSE THERE'S

4708
02:51:10,010 --> 02:51:11,679
CHANGES IN THE LAWS AND RULES

4709
02:51:11,679 --> 02:51:12,646
AND REGULATIONS, I'M IN THE

4710
02:51:12,646 --> 02:51:14,448
STATE OF CALIFORNIA WHERE WE

4711
02:51:14,448 --> 02:51:17,451
HAVE A STATE LEGISLATURES WHO

4712
02:51:17,451 --> 02:51:18,719
ARE INTRODUCING LOTS OF NEW

4713
02:51:18,719 --> 02:51:20,287
BILLS AROUND THE REGULATION OF

4714
02:51:20,287 --> 02:51:22,756
AI, AND MAKING SURE THAT IT IS

4715
02:51:22,756 --> 02:51:26,393
SAFE AND EFFECTIVE FOR PATIENTS.

4716
02:51:26,393 --> 02:51:29,630
SO SO THIS IS A VERY LENGTHY AND

4717
02:51:29,630 --> 02:51:30,998
COMPLICATED PROCESS THAT WE HAVE

4718
02:51:30,998 --> 02:51:32,533
TO GO THROUGH TO CREATE A

4719
02:51:32,533 --> 02:51:36,237
CLINICALLY EFFECTIVE AND USEABLE

4720
02:51:36,237 --> 02:51:36,470
MODEL.

4721
02:51:36,470 --> 02:51:38,239
RIGHT, I WILL TAKE MY LAST FEW

4722
02:51:38,239 --> 02:51:39,940
MINUTES TO TELL YOU A FEW WORDS

4723
02:51:39,940 --> 02:51:43,577
ABOUT WHAT I'M INTERESTED IN

4724
02:51:43,577 --> 02:51:46,347
THIS DEVELOPING AI TOOLS TO USE

4725
02:51:46,347 --> 02:51:49,683
DATA EFFECTIVELY IN A LEARNING

4726
02:51:49,683 --> 02:51:50,951
HEALTH SYSTEM ENVIRONMENT AND

4727
02:51:50,951 --> 02:51:54,255
I'M INTEREST INDEED

4728
02:51:54,255 --> 02:51:55,089
ACCESSIBILITY AND DEMOCRATIZING

4729
02:51:55,089 --> 02:51:57,057
AI, MAKING IT EASY FOR

4730
02:51:57,057 --> 02:51:58,025
CLINICIANS AND BIOLOGISTS AND

4731
02:51:58,025 --> 02:51:59,193
EVERYBODY TO BENEFIT FROM IT, SO

4732
02:51:59,193 --> 02:52:03,164
YOU DON'T HAVE TO BE A DATA

4733
02:52:03,164 --> 02:52:04,431
SCIENTIST OR A COMPUTER

4734
02:52:04,431 --> 02:52:05,266
SCIENTIST, AND WE'VE DEVELOPED

4735
02:52:05,266 --> 02:52:08,569
WHAT WE CALL AN ECOSYSTEM FOR

4736
02:52:08,569 --> 02:52:09,904
EXPLAINABLE AI AND THIS COMBINES

4737
02:52:09,904 --> 02:52:11,639
A LOT OF DIFFERENT PIECES AND

4738
02:52:11,639 --> 02:52:13,908
PARTS BUT BASICALLY WHAT WE'RE

4739
02:52:13,908 --> 02:52:17,878
DOING HERE IS PUTTING CURATED

4740
02:52:17,878 --> 02:52:19,947
DATA, PUBLIC KNOWLEDGE ABOUT

4741
02:52:19,947 --> 02:52:22,316
YEENS AND DISEASE, AND DRUGS AS

4742
02:52:22,316 --> 02:52:24,084
WELL AS CODE AND RESEARCH

4743
02:52:24,084 --> 02:52:25,819
RESULTS INTO WHAT'S CALLED A

4744
02:52:25,819 --> 02:52:26,420
GRAPH DATABASE.

4745
02:52:26,420 --> 02:52:30,791
SO WE TAKE CODE AND RESULTS AND

4746
02:52:30,791 --> 02:52:33,294
KNOWLEDGE, AND DATA AND WE LINK

4747
02:52:33,294 --> 02:52:34,828
IT ALL IN A GRAPH SO WE

4748
02:52:34,828 --> 02:52:35,863
UNDERSTAND THE RELATIONSHIPS

4749
02:52:35,863 --> 02:52:37,932
BETWEEN ALL OF THOSE ENTITIES,

4750
02:52:37,932 --> 02:52:39,200
AND WE'VE BUILT LARGE LANGUAGE

4751
02:52:39,200 --> 02:52:41,735
MODEL TOOLS WHERE WE CAN TART TO

4752
02:52:41,735 --> 02:52:43,938
ASK QUESTIONS ABOUT THE DATA, WE

4753
02:52:43,938 --> 02:52:45,806
CAN LAUNCH WITH JUST A FEW WORDS

4754
02:52:45,806 --> 02:52:47,141
A MACHINE LEARNING ANALYSIS.

4755
02:52:47,141 --> 02:52:48,742
WE CAN INTERROGATE THE RESULTS

4756
02:52:48,742 --> 02:52:50,844
JUST AS WE WOULD A DATA SCIENCE

4757
02:52:50,844 --> 02:52:51,979
COLLEAGUE, AND SO THE IDEA IS

4758
02:52:51,979 --> 02:52:53,847
THAT THIS WILL MAKE IT EASY FOR

4759
02:52:53,847 --> 02:52:55,816
PENAL TO DO COMPLICATED MACHINE

4760
02:52:55,816 --> 02:52:57,017
LEARNING ANALYSIS, ASK QUESTIONS

4761
02:52:57,017 --> 02:52:59,019
ABOUT THE RESULTS, GAIN AN

4762
02:52:59,019 --> 02:52:59,787
UNDERSTANDING OF THE RESULTS AND

4763
02:52:59,787 --> 02:53:01,789
ALL OF THIS IS BASED ON AN

4764
02:53:01,789 --> 02:53:03,924
ONTOLOGY THAT WE BUILT WHERE WE

4765
02:53:03,924 --> 02:53:07,328
CAN MODEL THE RELATIONSHIPS AND

4766
02:53:07,328 --> 02:53:08,329
UNDERSTAND THE SEMANTIC

4767
02:53:08,329 --> 02:53:09,063
RELATIONSHIPS BETWEEN CODE AND

4768
02:53:09,063 --> 02:53:11,599
DATA AND KNOWLEDGE AND RESULTS

4769
02:53:11,599 --> 02:53:13,133
AND ANNOTATIONS AND SO THIS IS

4770
02:53:13,133 --> 02:53:15,669
WHAT ALLOWS US TO PUT ALL OF

4771
02:53:15,669 --> 02:53:17,104
THESE ENTITIES INTO A GRAPH AND

4772
02:53:17,104 --> 02:53:20,207
BE ABLE TO BETTER UNDERSTAND HOW

4773
02:53:20,207 --> 02:53:22,576
THEY ARE WORK TOGETHER AND ALLOW

4774
02:53:22,576 --> 02:53:25,346
A LARGE LANGUAGE MODEL LIKE CHAT

4775
02:53:25,346 --> 02:53:27,915
GPT TO ASK INTELLIGENT QUESTIONS

4776
02:53:27,915 --> 02:53:28,215
ABOUT IT.

4777
02:53:28,215 --> 02:53:30,551
AND THIS IS A PAPER WE PUBLISHED

4778
02:53:30,551 --> 02:53:33,721
RECENTLY A METHOD CALLED

4779
02:53:33,721 --> 02:53:35,923
ESCARGO, WHICH IS AN EXCELLENT

4780
02:53:35,923 --> 02:53:37,524
LANGUAGE BASED MODEL DESIGNED TO

4781
02:53:37,524 --> 02:53:39,660
ASK QUESTIONS ABOUT A DATABASE

4782
02:53:39,660 --> 02:53:40,294
LIKE THIS.

4783
02:53:40,294 --> 02:53:42,263
AND WE SHOWED WITH HUNDREDS OF

4784
02:53:42,263 --> 02:53:44,331
DIFFERENT TYPES OF QUESTIONS

4785
02:53:44,331 --> 02:53:47,134
ABOUT THE GRAPH, WE SHOWED THAT

4786
02:53:47,134 --> 02:53:51,338
OUR ESCARGO METHOD ACHIEVES 80

4787
02:53:51,338 --> 02:53:54,074
HEVER 90% ACCURACY AND ANSWERING

4788
02:53:54,074 --> 02:53:55,809
THOSE QUESTIONS WHICH IS MUCH

4789
02:53:55,809 --> 02:53:58,078
BETTER THAN CHAT GPT WHICH

4790
02:53:58,078 --> 02:53:58,712
UNDERSTANDS VERY LITTLE ABOUT

4791
02:53:58,712 --> 02:53:59,747
THE KNOWLEDGE WE HAVE IN OUR

4792
02:53:59,747 --> 02:54:02,449
GRAPH AND THIS IS ALL PUBLISHED

4793
02:54:02,449 --> 02:54:03,951
AND OPEN SOURCE SOFTWARE.

4794
02:54:03,951 --> 02:54:05,185
SO I WILL STOP THERE AND LOOKING

4795
02:54:05,185 --> 02:54:06,387
FORWARD TO THE REST OF THE PANEL

4796
02:54:06,387 --> 02:54:09,590
AND AGAIN, YOU KNOW MY GOAL IS

4797
02:54:09,590 --> 02:54:10,924
TO MAKE -- ACCELERATE RESEARCH

4798
02:54:10,924 --> 02:54:12,793
BY MAKING IT EASY AND ACCESSIBLE

4799
02:54:12,793 --> 02:54:17,264
AND I WILL JUST THANK MY TEAM,

4800
02:54:17,264 --> 02:54:18,799
ECOXAI TEAM, MY NIH FUNDING AND

4801
02:54:18,799 --> 02:54:19,967
AGAIN THERE'S MY E-MAIL ADDRESS

4802
02:54:19,967 --> 02:54:21,835
AND THIS IS WHERE WE'RE LOCATED

4803
02:54:21,835 --> 02:54:23,337
IN WEST HOLLYWOOD, THIS IS THE

4804
02:54:23,337 --> 02:54:24,505
PACIFIC DESIGN CENTER THAT WE

4805
02:54:24,505 --> 02:54:25,739
CALL THE NORTH CAMPUS WHICH IS

4806
02:54:25,739 --> 02:54:28,742
ABOUT A 10 MINUTE WALK FROM THE

4807
02:54:28,742 --> 02:54:30,010
MAIN CEDAR SINAI HOSPITAL WHERE

4808
02:54:30,010 --> 02:54:31,912
WE LEASE RESEARCH SPACE AND ON -

4809
02:54:31,912 --> 02:54:42,356
IMON THE FIFTH FLOOR OF THE

4810
02:54:42,356 --> 02:54:42,723
GREEN BUILDING.

4811
02:54:42,723 --> 02:54:44,858
>> THANK YOU DR. MOORE FOR
THE

4812
02:54:44,858 --> 02:54:47,261
QUICK WHIRL WIND TOUR OF DATA

4813
02:54:47,261 --> 02:54:49,096
SCIENCE AND NONE OF US CAN LIVE

4814
02:54:49,096 --> 02:54:50,164
WITHOUT DATA SCIENCE AND I WOULD

4815
02:54:50,164 --> 02:54:52,199
LOVE TO GET TO THE DISCUSSION

4816
02:54:52,199 --> 02:54:54,301
PORTION OF THIS PROGRAM TO TALK

4817
02:54:54,301 --> 02:54:57,037
MORE ABOUT THE EXPLAINABLE AI IN

4818
02:54:57,037 --> 02:54:57,938
THE ECOSYSTEM.

4819
02:54:57,938 --> 02:54:58,906
SO THANK YOU.

4820
02:54:58,906 --> 02:55:02,142
OUR SECOND SPEAKER FOR THIS

4821
02:55:02,142 --> 02:55:04,311
AFTERNOON IS DR.A ELHADA D, AND

4822
02:55:04,311 --> 02:55:06,914
SHE IS THE CHAIR AND ASSOCIATE

4823
02:55:06,914 --> 02:55:12,152
PROFESSOR OF THE DEPARTMENT OF

4824
02:55:12,152 --> 02:55:13,821
BIOMEDICAL INFORMATICSAL

4825
02:55:13,821 --> 02:55:14,488
COLUMBIA UNIVERSITY VAGELOS

4826
02:55:14,488 --> 02:55:16,590
COLLEGE OF PHYSICIANS AND

4827
02:55:16,590 --> 02:55:16,857
SURGEONS.

4828
02:55:16,857 --> 02:55:21,028
AND DIRECTOR OF THE MEDICAL

4829
02:55:21,028 --> 02:55:22,229
INFORMATION SERVICES AT NEW YORK

4830
02:55:22,229 --> 02:55:24,598
PRESCRIBING BI TERRION HOSPITAL.

4831
02:55:24,598 --> 02:55:31,572
SHE LEADS THE AI AND BPS

4832
02:55:31,572 --> 02:55:33,640
INITIATIVE AND IN COLUMBIA'S

4833
02:55:33,640 --> 02:55:35,476
UNIVERSITY RESEARCH INIAATIVE ON

4834
02:55:35,476 --> 02:55:37,077
DATA POWERED WOMEN'S HEALTH.

4835
02:55:37,077 --> 02:55:39,213
HER RESEARCH SITS AT THE

4836
02:55:39,213 --> 02:55:41,315
INTERSECTION OF ARTIFICIAL

4837
02:55:41,315 --> 02:55:44,318
INTELLIGENCE, HUMAN CENTERED

4838
02:55:44,318 --> 02:55:47,755
COMPUTING AND MEDICINE WITH A

4839
02:55:47,755 --> 02:55:48,989
FOCUS ON DEVELOPING NOVEL

4840
02:55:48,989 --> 02:55:50,457
MACHINE LEARNING METHODS.

4841
02:55:50,457 --> 02:55:53,394
SHE DESIGNED AI DRIVEN TOOLS TO

4842
02:55:53,394 --> 02:55:55,729
SUPPORT PATIENTS AND CLINICIANS

4843
02:55:55,729 --> 02:55:59,666
INSURING THAT THE AI SYSTEM OF

4844
02:55:59,666 --> 02:56:02,870
THE FUTURE IS SAFE AND EFFECTIVE

4845
02:56:02,870 --> 02:56:05,172
AND ADVANCE MEDICINE,

4846
02:56:05,172 --> 02:56:06,473
DR. ELHADAD, I AM REALLY LOOKING

4847
02:56:06,473 --> 02:56:07,975
FORWARD TO YOUR PRESENTATION,

4848
02:56:07,975 --> 02:56:18,285
THE MIC IS YOURS.

4849
02:56:26,960 --> 02:56:28,862
WOULD YOU PLEASE UNMUTE, THANK

4850
02:56:28,862 --> 02:56:29,530
YOU?

4851
02:56:29,530 --> 02:56:30,497
>> I CAN UNMUTE.

4852
02:56:30,497 --> 02:56:31,465
THANK YOU.

4853
02:56:31,465 --> 02:56:31,799
HI, EVERYONE.

4854
02:56:31,799 --> 02:56:33,434
I WILL TALK TO YOU ABOUT A

4855
02:56:33,434 --> 02:56:35,936
ROADMAP THAT WE'VE BEEN THINKING

4856
02:56:35,936 --> 02:56:38,238
HERE AT COLUMBIA AND IN MY LAB

4857
02:56:38,238 --> 02:56:40,007
IN PARTICULAR ON AI POWERED

4858
02:56:40,007 --> 02:56:41,442
WOMEN'S HEALTH.

4859
02:56:41,442 --> 02:56:43,444
SO AS DR. SETO SAID I AM REALLY

4860
02:56:43,444 --> 02:56:47,514
MUCH AT THE INTERSECTION OF AI

4861
02:56:47,514 --> 02:56:49,383
AND WOMEN'S HEALTH.

4862
02:56:49,383 --> 02:56:50,918
THESE ARE THE ENTITIES THAT ARE

4863
02:56:50,918 --> 02:56:54,922
FUNDING MY WORK AND I'M VERY

4864
02:56:54,922 --> 02:56:58,258
GRATEFUL TO THEM AND CLUE THE

4865
02:56:58,258 --> 02:57:01,061
MENSTRUAL TRAWK AND ODESSY AND

4866
02:57:01,061 --> 02:57:02,129
THE OBSERVATIONAL HEALTH DATA

4867
02:57:02,129 --> 02:57:03,197
ARE MY DATA PARTNERS.

4868
02:57:03,197 --> 02:57:05,966
SO I WANT TO START BY SAYING

4869
02:57:05,966 --> 02:57:07,701
THAT THERE'S THIS PROMISE OF

4870
02:57:07,701 --> 02:57:12,206
DATA AI AND TECHNOLOGY, WHICH IS

4871
02:57:12,206 --> 02:57:13,941
I THINK ALONG 3 AXIS TO ELUC

4872
02:57:13,941 --> 02:57:15,843
DATE THE ROLES OF SEX AND GENDER

4873
02:57:15,843 --> 02:57:17,778
IN HEALTH TO IDENTIFY NEW

4874
02:57:17,778 --> 02:57:20,080
KNOWLEDGE, ABOUT WOMEN'S HEALTH,

4875
02:57:20,080 --> 02:57:21,114
NEW PHYSIOLOGICAL KNOWLEDGE AND

4876
02:57:21,114 --> 02:57:24,518
ALSO TO CREATE NEW SOLUTIONS

4877
02:57:24,518 --> 02:57:26,653
TECHNOLOGICAL SOLUTIONS TO

4878
02:57:26,653 --> 02:57:28,355
SUPPORT WOMEN, BUT IF WOMENS

4879
02:57:28,355 --> 02:57:33,126
HEALTH ON ITS OWN WAS A COMPLEX

4880
02:57:33,126 --> 02:57:34,995
TOPIC ADDING DATA AND AI

4881
02:57:34,995 --> 02:57:38,532
TECHNOLOGY ADDS AN ADDITIONAL

4882
02:57:38,532 --> 02:57:41,401
LAYER OF COMPLEXITY.

4883
02:57:41,401 --> 02:57:43,070
AND SO, THE BULK OF MY TALK

4884
02:57:43,070 --> 02:57:46,406
REALLY IS HOW DO WE GO ABOUT

4885
02:57:46,406 --> 02:57:49,009
THINKING ABOUT HOW AI CAN HELP

4886
02:57:49,009 --> 02:57:51,545
WITHOUT HARMING AND THE TRDR OF

4887
02:57:51,545 --> 02:57:54,615
THE BIG OUTLINE OF THIS TALK IS

4888
02:57:54,615 --> 02:57:56,783
AI TECHNIQUES THAT ACCOUNT FOR

4889
02:57:56,783 --> 02:57:59,019
THE BIASES OF THE DATA AND ABOUT

4890
02:57:59,019 --> 02:58:00,420
WOMEN'S HEALTH IN PARTICULAR

4891
02:58:00,420 --> 02:58:02,089
THAT ARE ENCODED IN THE

4892
02:58:02,089 --> 02:58:03,490
DALLASCOWBOYS.COM DATA HUMAN

4893
02:58:03,490 --> 02:58:04,992
CENTERED AI APPROACHES THAT

4894
02:58:04,992 --> 02:58:06,860
INSURES A SOLUTIONS CREATED ARE

4895
02:58:06,860 --> 02:58:09,396
ALIGNED WITH THE NEEDS VALUES OF

4896
02:58:09,396 --> 02:58:10,531
INDIVIDUALS IN POPULATION AND

4897
02:58:10,531 --> 02:58:12,266
TEAM SCIENCE ARE GOING TO BE

4898
02:58:12,266 --> 02:58:21,842
CRITICAL TO DELIVERING ON THIS

4899
02:58:21,842 --> 02:58:22,209
PROMISE.

4900
02:58:22,209 --> 02:58:27,948
AND WE DO OVER ALL MENSTRUAL

4901
02:58:27,948 --> 02:58:29,950
HEALTH, ORAL CONTRACEPTION, PC

4902
02:58:29,950 --> 02:58:33,153
OS MENOPAUSE BUT I WILL USE

4903
02:58:33,153 --> 02:58:33,987
ENDOMETRIOSIS TO TALK ABOUT THE

4904
02:58:33,987 --> 02:58:37,157
WORK THAT WE DO.

4905
02:58:37,157 --> 02:58:39,860
AND I HOPE I CAN MOTIVATE THE

4906
02:58:39,860 --> 02:58:41,828
REASON TO WHERE I'M LOOKING AT

4907
02:58:41,828 --> 02:58:44,498
THIS PARTICULAR ASPECTS OF

4908
02:58:44,498 --> 02:58:46,967
ENDOMEDE RIRIOSEIS, 1 IS THAT IT

4909
02:58:46,967 --> 02:58:48,235
IS AN UNDERSTOOD CONDITION AND

4910
02:58:48,235 --> 02:58:49,503
UNDERSTAND STUDIED SO WE WILL

4911
02:58:49,503 --> 02:58:55,609
TRY TO DESCRIBE THE DISEASELET

4912
02:58:55,609 --> 02:58:57,678
SECONDON IS THAT I DON'T HAVE TO

4913
02:58:57,678 --> 02:59:01,481
TELL THIS AUDIENCE BUT THERE'S A

4914
02:59:01,481 --> 02:59:03,317
LONG DIAGNOSIS FOR ENDOMEET

4915
02:59:03,317 --> 02:59:07,921
RIOSEOSEIS AND COULD WE USE AI

4916
02:59:07,921 --> 02:59:09,790
FOR DETECTION, THERE'S A LOT OF

4917
02:59:09,790 --> 02:59:12,092
WORK IN BIOMARKERS AND

4918
02:59:12,092 --> 02:59:14,494
NONEVASIVE TESTS AND HERE'S THE

4919
02:59:14,494 --> 02:59:15,796
IDEA, IS CAN WE USE EXISTING

4920
02:59:15,796 --> 02:59:20,367
DATA AND SYSTEMS IN PLACE BUT

4921
02:59:20,367 --> 02:59:21,635
NEVERTHELESS EPIABLE PATIENTS TO

4922
02:59:21,635 --> 02:59:24,471
ACCESS AN EARLIER DIAGNOSE.

4923
02:59:24,471 --> 02:59:29,676
AND THEN THE FACTS THERE'S THIS

4924
02:59:29,676 --> 02:59:40,120
COMPLEX SELF-MANAGEMENT TO

4925
02:59:41,922 --> 02:59:42,990
ENDOMEET RIAIAL DISEASE I WANT

4926
02:59:42,990 --> 02:59:44,858
TO SAY SOMETHING ABOUT TEAM

4927
02:59:44,858 --> 02:59:47,027
SCIENCE, IT'S VERY ORGANIZED, I

4928
02:59:47,027 --> 02:59:50,197
WAS HONORED TO GELT A WORKSHOP

4929
02:59:50,197 --> 02:59:53,800
AND NSF, AND MANY PEOPLE FROM

4930
02:59:53,800 --> 02:59:58,538
ORWH IN THE AUDIENCE AS WELL,

4931
02:59:58,538 --> 03:00:04,945
AND THAT WAS ABOUT USING AI TO

4932
03:00:04,945 --> 03:00:06,113
BETTER UNDERSTAND MENEE PAUSE

4933
03:00:06,113 --> 03:00:07,547
AND THE OTHER HALF WHERE THE AI

4934
03:00:07,547 --> 03:00:10,951
SCIENTISTS AND IT WAS A

4935
03:00:10,951 --> 03:00:14,454
FANTASTIC 2 DAYS AT COLUMBIA

4936
03:00:14,454 --> 03:00:15,522
UNIVERSITY THESE ARE 2 THYSELF

4937
03:00:15,522 --> 03:00:17,224
ARE 2 INITIATIVE THAT I WILL

4938
03:00:17,224 --> 03:00:19,826
MENTION THAT ARE SPECIFICALLY AT

4939
03:00:19,826 --> 03:00:21,528
THE INTERSECTION OF TECHNOLOGY

4940
03:00:21,528 --> 03:00:23,497
AND EM'S HEALTH WHICH IS WHAT I

4941
03:00:23,497 --> 03:00:25,499
LEAD AND EMERGE WHICH SIGNIFY

4942
03:00:25,499 --> 03:00:27,434
PARTICIPATE AND IS PART OF

4943
03:00:27,434 --> 03:00:31,038
ENGINEERING FOR WOMEN'S HEALTH.

4944
03:00:31,038 --> 03:00:40,280
SO THIS ROADMAP I WILL STOP

4945
03:00:40,280 --> 03:00:41,348
ENDOMEDE RIOSEIS AND AND HERE I

4946
03:00:41,348 --> 03:00:44,117
WILL TELL YOU QUICKLY ABOUT NEW

4947
03:00:44,117 --> 03:00:45,686
DATA AND TOOLS AND HOW THAT CAN

4948
03:00:45,686 --> 03:00:49,556
HELP US LEAD TO NEW INSIGHTS

4949
03:00:49,556 --> 03:00:51,958
IT'S ABOUTEND SO AGAIN I LIKE TO

4950
03:00:51,958 --> 03:00:57,698
TELL THE OUTLINE BEFORE I SHOW

4951
03:00:57,698 --> 03:00:58,965
YOU EVERYTHING THERE'S 3 TYPES

4952
03:00:58,965 --> 03:01:00,634
OF INSIGHT, 1 ABOUT HUMAN

4953
03:01:00,634 --> 03:01:04,638
CENTERED APPROACHES, 1 ABOUT AI

4954
03:01:04,638 --> 03:01:05,939
TECH INSIGHTS AND 1 ABOUT WHAT

4955
03:01:05,939 --> 03:01:07,774
HAVE WE LEARNED ABOUT THE

4956
03:01:07,774 --> 03:01:10,277
DISEASE, IN THIS CASE

4957
03:01:10,277 --> 03:01:13,680
ENDOMETRIOSIS AND THE HUMAN WITH

4958
03:01:13,680 --> 03:01:14,948
INSEAT DISMESS THE AND WANT TO

4959
03:01:14,948 --> 03:01:16,216
CONTRIBUTE TO SCIENCE BUT THEY

4960
03:01:16,216 --> 03:01:22,155
WANT TO DO SO UNDER SPECIFIC

4961
03:01:22,155 --> 03:01:23,256
CONDITIONS AND IN PARTICULAR

4962
03:01:23,256 --> 03:01:25,459
PRIVACY IS A REALLY, REALLY BIG

4963
03:01:25,459 --> 03:01:28,995
DEAL WORRY PATIENTS WITH ENDOME

4964
03:01:28,995 --> 03:01:31,431
RIOSEIS, AND AI IN HIGH-TECH, WE

4965
03:01:31,431 --> 03:01:34,401
USE MOBILE HEALTH TO ENGAGE

4966
03:01:34,401 --> 03:01:36,636
DAY-TO-DAY PATIENTS TO TELL US

4967
03:01:36,636 --> 03:01:38,839
ABOUT THEIR DISEASE AND THAT

4968
03:01:38,839 --> 03:01:42,275
ISN'T ACTUALLY USEFUL TYPE OF

4969
03:01:42,275 --> 03:01:43,210
TECHNOLOGY ESPECIALLY WHEN THERE

4970
03:01:43,210 --> 03:01:45,278
ARE DISEASES THAT HAVE

4971
03:01:45,278 --> 03:01:49,382
DAY-TO-DAY VARIATIONSIATIONS IN

4972
03:01:49,382 --> 03:01:51,752
SYMPTOMS, AI METHODS THAT ARE

4973
03:01:51,752 --> 03:01:54,921
LOOKING TO MIDIGATE DATA ARE

4974
03:01:54,921 --> 03:01:57,390
CRITICAL IN THE CASE OF MOBILE

4975
03:01:57,390 --> 03:01:59,259
HEALTH, WE NEED TO TAKE INTO

4976
03:01:59,259 --> 03:02:02,462
ACCOUNT NOT EVERYONE WILL

4977
03:02:02,462 --> 03:02:03,597
RESPOND TO QUESTIONS DAY-TO-DAY,

4978
03:02:03,597 --> 03:02:06,600
SOME MIGHT DO IT ONCE IN A WHILE

4979
03:02:06,600 --> 03:02:08,702
AND SEVERAL TIMES A DAY AND

4980
03:02:08,702 --> 03:02:10,537
MITIGATE FOR THIS POTENTIAL

4981
03:02:10,537 --> 03:02:13,507
CHANGES IN HEALTH DATA IS

4982
03:02:13,507 --> 03:02:17,677
COLLECTED AND FINALLY AI METHODS

4983
03:02:17,677 --> 03:02:20,947
ARE NEEDED BECAUSE WE HAVE THE

4984
03:02:20,947 --> 03:02:23,784
PATTERNS OF DISEASE AND SO AND

4985
03:02:23,784 --> 03:02:25,652
SO NEWER MOTHERS ARE ACTUALLY

4986
03:02:25,652 --> 03:02:29,589
VERY HELPFUL AND FIEBALLY ON

4987
03:02:29,589 --> 03:02:30,290
ENDOMITTRYOSE ESTIMATE THAD THAT

4988
03:02:30,290 --> 03:02:33,727
WE'VE DONE WITH THE MOBILE HOUSE

4989
03:02:33,727 --> 03:02:35,028
TECHNOLOGIES TO CONFIRM THE

4990
03:02:35,028 --> 03:02:37,898
ASPECT, BUT ALSO THE FACT THAT

4991
03:02:37,898 --> 03:02:39,966
IT'S HIGH -LY HETEROGENEOUS AND

4992
03:02:39,966 --> 03:02:43,870
WE CAN PROPOSE NEW SET PROPOSAL

4993
03:02:43,870 --> 03:02:45,038
FOR SUBTYPING OF ENDOMETRIOSIS

4994
03:02:45,038 --> 03:02:46,640
AND FINALLY THERE'S VALUE IN

4995
03:02:46,640 --> 03:02:48,842
LOOKING AT THIS VERY GRANULAR

4996
03:02:48,842 --> 03:02:50,177
TEMPORAL VARIATIONS BECAUSE IT

4997
03:02:50,177 --> 03:02:52,379
ALSO INFORMS WHAT'S HAPPENING

4998
03:02:52,379 --> 03:02:54,114
WITH ENDOMEET RIOSEIS SO WE

4999
03:02:54,114 --> 03:03:02,455
CREATED A PROJECT CALLED

5000
03:03:02,455 --> 03:03:03,490
CITIZEN-ENDO, THAT ARE PATIENTS

5001
03:03:03,490 --> 03:03:05,058
WITH LIVED EXPERIENCES IN

5002
03:03:05,058 --> 03:03:06,526
ENDOMETRIOSIS AND AT THE SAME

5003
03:03:06,526 --> 03:03:08,128
TIME KNOWLEDGE OF THE CONDITION

5004
03:03:08,128 --> 03:03:09,496
AND SECOND BUILT TO SUPPORT THEM

5005
03:03:09,496 --> 03:03:12,699
SO WE HAVE A COMMUNITY OF ABOUT

5006
03:03:12,699 --> 03:03:14,100
19,000 PATIENTS, 9000 IN THE

5007
03:03:14,100 --> 03:03:15,936
U.S., WE WORK ACROSS MULTIPLE

5008
03:03:15,936 --> 03:03:18,138
LANGUAGES AND IT'S AN EXTREMELY

5009
03:03:18,138 --> 03:03:21,474
REWARDING TYPE OF ACTIVITY AND 1

5010
03:03:21,474 --> 03:03:26,680
OF THEM IS TO PARTNER WITH

5011
03:03:26,680 --> 03:03:27,948
PATIENTS IN DETERMINING WHICH

5012
03:03:27,948 --> 03:03:30,750
QUESTIONS WE'RE ASKING ABOUT

5013
03:03:30,750 --> 03:03:32,652
ENDOMIGHT REOSEIS, DECIDING HOW

5014
03:03:32,652 --> 03:03:33,854
IT GETS COLLECTED AND

5015
03:03:33,854 --> 03:03:34,654
INTERESTED, AND IN ORDINANCE

5016
03:03:34,654 --> 03:03:36,022
NUMBER TORE ENGAGE WITH OUR

5017
03:03:36,022 --> 03:03:46,700
COMMUNITY WE DO A LOT ADVOCACY

5018
03:03:46,700 --> 03:03:47,234
AND DATA MANAGEMENT.

5019
03:03:47,234 --> 03:03:50,470
WE DID A LOT OF INTEREST IN HOW

5020
03:03:50,470 --> 03:03:52,906
DO YOU DESIGN THAT ASKS PATIENTS

5021
03:03:52,906 --> 03:03:55,075
WHAT IS HAPPENING WITH THEIR

5022
03:03:55,075 --> 03:03:56,409
DISEASE WHEN IN THE LITERATURE

5023
03:03:56,409 --> 03:04:02,249
THERE'S NOT A LOT ABOUT

5024
03:04:02,249 --> 03:04:02,949
DAY-TO-DAY DESCRIPTIONS ABOUT

5025
03:04:02,949 --> 03:04:09,856
EBD  -- EPPED O MEET RIOSEIS, AD

5026
03:04:09,856 --> 03:04:12,592
THIS IS AN EXAMPLE WHEN WE HAD

5027
03:04:12,592 --> 03:04:14,094
10,000 PARTICIPANTS WE STARTED

5028
03:04:14,094 --> 03:04:16,596
CREATING A MAN OF PAIN AND I

5029
03:04:16,596 --> 03:04:18,999
HOPE THAT SHES YOU IF ANYTHING

5030
03:04:18,999 --> 03:04:20,600
THE SYSTEM ASPECT FROM THE PAIN

5031
03:04:20,600 --> 03:04:24,304
LEVEL OF THIS DISEASE.

5032
03:04:24,304 --> 03:04:26,573
THERE'S ALSO AND ALSO TEMPORAL

5033
03:04:26,573 --> 03:04:27,440
VALID AND RELIABLEINATION, THIS

5034
03:04:27,440 --> 03:04:30,343
IS WEEK BY WEEK, THIS IS THIS

5035
03:04:30,343 --> 03:04:32,512
CHANGE IN HOW BAD THEY'RE GOING

5036
03:04:32,512 --> 03:04:38,451
AND WHEN WE USE AI TO GO AND

5037
03:04:38,451 --> 03:04:42,422
RATHER THAN JUST A THING, WE

5038
03:04:42,422 --> 03:04:44,658
ALSO SEE THAT PATIENTS HAVE

5039
03:04:44,658 --> 03:04:47,994
DRASTIC WEEK BY WEEK CHANGES IN

5040
03:04:47,994 --> 03:04:53,900
HEALTH TRAJECTORIES SO THIS IS

5041
03:04:53,900 --> 03:04:55,969
ACROSS 50 WEEKS IN SO IT'S A LOT

5042
03:04:55,969 --> 03:04:59,539
OF TIME NEARLY A YEAR BUT THESE

5043
03:04:59,539 --> 03:05:02,008
ARE INDIVIDUAL PATIENT

5044
03:05:02,008 --> 03:05:02,842
TRAJECTORIES AND THE PATIENT

5045
03:05:02,842 --> 03:05:04,477
CODE SUGGEST HOW ABOUT BAD OR

5046
03:05:04,477 --> 03:05:06,446
WELL THEY'RE DOING THAT WORK

5047
03:05:06,446 --> 03:05:08,515
ACCORDING TO AI SUMMARY METRIC

5048
03:05:08,515 --> 03:05:13,653
AND AT 1 POINT ABOUT

5049
03:05:13,653 --> 03:05:14,688
ENDOMETRIOSIS, IS THAT THINGS

5050
03:05:14,688 --> 03:05:16,423
ARE OKAY OUT OF PERIOD AND

5051
03:05:16,423 --> 03:05:17,958
THINGS ARE REALLY BAD DURING

5052
03:05:17,958 --> 03:05:23,430
PERIOD BUT THAT'S NOT WHAT THE

5053
03:05:23,430 --> 03:05:27,634
DATA IS TELLING US AND HOW BAD

5054
03:05:27,634 --> 03:05:33,206
OR GOOD OR  A WEEK IS FOR A PAT.

5055
03:05:33,206 --> 03:05:36,543
SO I SHOWED YOU NEW DATA TYPE

5056
03:05:36,543 --> 03:05:39,879
AND GIVING US NEW INSIGHTS, BUT

5057
03:05:39,879 --> 03:05:41,348
WE ALSO AND I THINK THAT'S

5058
03:05:41,348 --> 03:05:45,852
IMPORTANT FUND FOR WOMEN'S

5059
03:05:45,852 --> 03:05:48,254
HEALTH IS THAT YES IS SOMETHING

5060
03:05:48,254 --> 03:05:50,590
WE CAN USE IN PARTICULAR

5061
03:05:50,590 --> 03:05:57,097
OBSERVATIONAL HELT DATA SO I

5062
03:05:57,097 --> 03:05:58,932
WANT TO GIVE A FANTASTIC

5063
03:05:58,932 --> 03:06:00,467
OVERVIEW OF ALL THE THINGS WE

5064
03:06:00,467 --> 03:06:02,435
HAVE IN OUR RESEARCH BUT THE 1

5065
03:06:02,435 --> 03:06:05,772
OF DEFINITION IS PROBLEMATIC AND

5066
03:06:05,772 --> 03:06:06,706
PARTICULARLY PROBLEMATIC IN

5067
03:06:06,706 --> 03:06:11,077
WOMEN'S HEALTH, SO WHO HAS

5068
03:06:11,077 --> 03:06:11,578
ENDOMETRIOSIS, PHENOTYPE

5069
03:06:11,578 --> 03:06:12,779
DEFINITION, DEPENDING ON HOW WE

5070
03:06:12,779 --> 03:06:14,147
DO SO BASED ON WHICH

5071
03:06:14,147 --> 03:06:15,048
GUIDELININGS WE PAY ATTENTION

5072
03:06:15,048 --> 03:06:16,449
TO, WE WILL FIND VERY DIFFERENT

5073
03:06:16,449 --> 03:06:19,853
TYPES OF PATIENTS AND SO THIS

5074
03:06:19,853 --> 03:06:24,924
PAPER, DESCRIBES WHEN WE USE

5075
03:06:24,924 --> 03:06:25,625
LAPROSCOPIC SURGERY, PATHOLOGY

5076
03:06:25,625 --> 03:06:27,227
AS THE GOLD STANDARD OR WHETHER

5077
03:06:27,227 --> 03:06:28,628
WE USE THE MORE RECENT

5078
03:06:28,628 --> 03:06:30,764
GUIDELINES THAT ARE SYMPTOMS

5079
03:06:30,764 --> 03:06:34,701
BASED TO IDENTIFY WHO ARE

5080
03:06:34,701 --> 03:06:35,969
PATIENTS WITH ENDOMETRIOSIS AND

5081
03:06:35,969 --> 03:06:38,238
YOU WILL SEE HERE IN THIS

5082
03:06:38,238 --> 03:06:41,541
DIAGRAM, IT'S NOT A SUBSET, IT'S

5083
03:06:41,541 --> 03:06:45,545
REALLY DIFFERENT COHORTS OF

5084
03:06:45,545 --> 03:06:47,747
PEOPLE WE ARE CAPTURE WILL.

5085
03:06:47,747 --> 03:06:49,249
NEVERTHELESS, AND THANKS TO A

5086
03:06:49,249 --> 03:06:52,352
LOT OF COMMON DATA MODELS AND

5087
03:06:52,352 --> 03:06:53,653
AND MANY DIFFERENT PARTNERS IN

5088
03:06:53,653 --> 03:06:56,823
THIS LARGE DATA NETWORKS WE'RE

5089
03:06:56,823 --> 03:07:01,494
ABLE TO GATHER NEW INSIGHTS

5090
03:07:01,494 --> 03:07:02,762
ABOUT ENDOMETRIOSIS AND MORE

5091
03:07:02,762 --> 03:07:04,497
IMPORTANTLY REAL WORLD INSIGHT

5092
03:07:04,497 --> 03:07:08,968
SO HERE'S THERE'S' COMPARISON OF

5093
03:07:08,968 --> 03:07:09,702
2 BHILLION ENDOMETRIOSIS

5094
03:07:09,702 --> 03:07:10,970
PATIENTS AND IDENTIFY THE

5095
03:07:10,970 --> 03:07:11,905
DEFINITION AND COMPARE THEM TO

5096
03:07:11,905 --> 03:07:13,973
EVERY WOMEN WE CAN HAVE OUR

5097
03:07:13,973 --> 03:07:17,844
HANDS ON IN REPRODUCTIVE AGE.

5098
03:07:17,844 --> 03:07:18,912
SO ABOUT 188 MILLION WOMEN.

5099
03:07:18,912 --> 03:07:21,548
AND WE SEE VERY CLEAR PATTERNS,

5100
03:07:21,548 --> 03:07:23,016
MAYBE NOT THE 1S THAT WE THINK

5101
03:07:23,016 --> 03:07:24,484
OF WHEN WE LOOK AT GUIDELINES

5102
03:07:24,484 --> 03:07:27,120
BUT THESE ARE THE REAL PATTERNS

5103
03:07:27,120 --> 03:07:30,056
OF DOCUMENTATION OF CARE OF

5104
03:07:30,056 --> 03:07:37,597
ENDOMEET REOSEIS PATIENTS AND

5105
03:07:37,597 --> 03:07:38,198
NONENDOMEET REOSEIS PATIENTS,

5106
03:07:38,198 --> 03:07:39,799
AND I WANT TO TALK ABOUT THE

5107
03:07:39,799 --> 03:07:44,571
QUESTION OF EARLY DETECTION IS

5108
03:07:44,571 --> 03:07:45,939
SIGNIFICANT IN ENDOMETRIOSIS,

5109
03:07:45,939 --> 03:07:49,909
AND THERE'S SIGNIFY 6 YEAR

5110
03:07:49,909 --> 03:07:51,411
LAGGING DIAGNOSIS SO HERE WE

5111
03:07:51,411 --> 03:07:57,684
ASKING THE QUESTION OF USING

5112
03:07:57,684 --> 03:07:59,219
HEALTH RECORD DATA OR CLAIMS

5113
03:07:59,219 --> 03:08:01,521
DATA CAN WE GO BACK IN TIME AND

5114
03:08:01,521 --> 03:08:05,391
SEE COULD WE HAVE IDENTIFIED THE

5115
03:08:05,391 --> 03:08:07,827
PEOPLE WITH ENDOMETRIOSIS AND

5116
03:08:07,827 --> 03:08:10,597
I'M SHOWING YOU HERE THE

5117
03:08:10,597 --> 03:08:14,134
PERFORMANCE IS AURP, SO IT'S A

5118
03:08:14,134 --> 03:08:16,002
PRECISION RECALL CURVE FOR

5119
03:08:16,002 --> 03:08:17,003
DIFFERENT CLASSIFIERS OF THE

5120
03:08:17,003 --> 03:08:20,807
SAME PATIENTS BUT GOING BACK IN

5121
03:08:20,807 --> 03:08:24,944
TIME AND ASKING COULD WE HAVE

5122
03:08:24,944 --> 03:08:26,012
GUESSED WHO HAD ENDOMITTRYOSE IN

5123
03:08:26,012 --> 03:08:30,216
HERE AND THE RESULTS ARE VERY

5124
03:08:30,216 --> 03:08:31,284
PROMISING WHERE EVEN 2.5 YEARS

5125
03:08:31,284 --> 03:08:36,322
IN ADVANCE WE COULD HAVE GUESSED

5126
03:08:36,322 --> 03:08:42,162
THE 71.9 AUPRC WHO HAD

5127
03:08:42,162 --> 03:08:43,463
ENDOMETRIOSIS SO WITH THE HELP

5128
03:08:43,463 --> 03:08:45,598
WITH THE WOMEN'S HELT AND

5129
03:08:45,598 --> 03:08:47,467
PARTNERSHIP WITH THE NEW YORK

5130
03:08:47,467 --> 03:08:49,169
PRESCRIBING BI TERRION HOSPITAL,

5131
03:08:49,169 --> 03:08:51,604
WE ARE TESTING THIS -- THE NEXT

5132
03:08:51,604 --> 03:08:54,574
PHASE WHICH IS ONCE YOU HAVE AN

5133
03:08:54,574 --> 03:08:55,441
ALGORITHM LIKE DR. MOORE

5134
03:08:55,441 --> 03:08:57,443
MENTIONED MOW DO WE GO BACK

5135
03:08:57,443 --> 03:08:58,945
MAKING IT HAPPEN IN PRACTICE.

5136
03:08:58,945 --> 03:09:04,551
SO WE ARE SETTING UP AN

5137
03:09:04,551 --> 03:09:05,618
INTERVENTION WHERE WHEN A WOMAN

5138
03:09:05,618 --> 03:09:09,722
WHO DID NOT HAVE A DIAGNOSIS OF

5139
03:09:09,722 --> 03:09:11,658
ENDOMETRIOSIS COME TO THE

5140
03:09:11,658 --> 03:09:13,426
EMERGENCY DEPARTMENT.

5141
03:09:13,426 --> 03:09:15,495
IN OUR DATA ANALYSIS WOMEN WITH

5142
03:09:15,495 --> 03:09:19,966
ENDOHAVE 3 TIMES OFERATE OF ED

5143
03:09:19,966 --> 03:09:21,901
VISIT THAN NONENDO PATIENTS AND

5144
03:09:21,901 --> 03:09:24,404
THEY COMPLAIN OF ABDOMINAL PAIN

5145
03:09:24,404 --> 03:09:27,740
OR PELVIC PAIN, THERE'S AN AI

5146
03:09:27,740 --> 03:09:29,142
MODTHEY'LL DOES AN OPPORTUNISTIC

5147
03:09:29,142 --> 03:09:31,678
MODELS THAT LOOKS BACK AT LONG

5148
03:09:31,678 --> 03:09:34,581
NUDEINAL EHR DATA AND STAYS, YOU

5149
03:09:34,581 --> 03:09:35,515
KNOW MAYBE THERE'S SOMETHING

5150
03:09:35,515 --> 03:09:37,050
THAT NEEDS TO BE LOOKED AT HERE,

5151
03:09:37,050 --> 03:09:39,419
IT'S NOT A DIAGNOSIS MODEL, IT'S

5152
03:09:39,419 --> 03:09:40,453
REALLY A REFERRAL MODEL AND THE

5153
03:09:40,453 --> 03:09:43,523
GOAL HERE IS TO BRING THE

5154
03:09:43,523 --> 03:09:46,259
PATIENT TO THE RIGHT CLINICIANS

5155
03:09:46,259 --> 03:09:48,895
SO THEY CAN INVESTIGATE FURTHER

5156
03:09:48,895 --> 03:09:50,063
WHETHER THEY HAVE ENDOMETRIOSIS

5157
03:09:50,063 --> 03:09:50,296
OR NOT.

5158
03:09:50,296 --> 03:09:52,465
BECAUSE WE KNOW OF OUR WORK ON

5159
03:09:52,465 --> 03:09:54,834
THE MORE BETTER HEALTH THAT

5160
03:09:54,834 --> 03:09:56,236
PATIENTS LIKE KNOWING AND BEING

5161
03:09:56,236 --> 03:09:58,871
PREPARED WHEN THEY GO SEE THEIR

5162
03:09:58,871 --> 03:10:00,139
DOCTORS WHAT THEIR PATTERNS OF

5163
03:10:00,139 --> 03:10:02,342
DISEASE ARE, WE SEND THEM A

5164
03:10:02,342 --> 03:10:04,844
REFERRAL FOR THE FENDO APP.

5165
03:10:04,844 --> 03:10:09,649
WHEN IT COMES TO COMPLEX

5166
03:10:09,649 --> 03:10:10,950
SELF-MANAGE NLT, I WANT TO

5167
03:10:10,950 --> 03:10:11,684
MENTION WORK THAT'S REALLY ABOUT

5168
03:10:11,684 --> 03:10:13,786
THE FACT THAT WE NEED TO CO

5169
03:10:13,786 --> 03:10:14,721
DESIGN AI SOLUTIONS WITH

5170
03:10:14,721 --> 03:10:15,688
PATIENTS AND PROVIDERS AND

5171
03:10:15,688 --> 03:10:17,991
THAT'S REALLY THE PART ABOUT

5172
03:10:17,991 --> 03:10:19,592
HUMAN CENTERED AI, SO I'M GIVING

5173
03:10:19,592 --> 03:10:21,961
HERE SOME OF THE COMPONENTS OF

5174
03:10:21,961 --> 03:10:25,865
HUMAN CENTERED AI, THE FIRST 1

5175
03:10:25,865 --> 03:10:28,735
IS DO PATIENTS EVEN WANT TO HAVE

5176
03:10:28,735 --> 03:10:30,336
INDIVIDUALS SUPPORT FROM AN AI

5177
03:10:30,336 --> 03:10:31,504
TECHNOLOGY, WE KNOW THAT MANY

5178
03:10:31,504 --> 03:10:34,274
PEOPLE ARE WORRIED ABOUT AI, AND

5179
03:10:34,274 --> 03:10:38,978
I THINK IN THE CASE AGAIN OF

5180
03:10:38,978 --> 03:10:39,879
STIGMATIZED CONDITION, ACTUALLY

5181
03:10:39,879 --> 03:10:41,547
THE OUTLOOK IS POSITIVE AND WE

5182
03:10:41,547 --> 03:10:43,616
HEAR THINGS LIKE AI CAN HEAR ME

5183
03:10:43,616 --> 03:10:45,351
BETTER THAN MY DOCTOR OR SHOWING

5184
03:10:45,351 --> 03:10:47,086
MY DATA GIVES ME A VOICE.

5185
03:10:47,086 --> 03:10:48,521
BUT THERE ARE PRINCIPLES WE NEED

5186
03:10:48,521 --> 03:10:52,058
TO BE CAREFUL ABOUT, SO, WE IN

5187
03:10:52,058 --> 03:10:54,160
THESE PAPERS WE LOOK INTO HUMAN

5188
03:10:54,160 --> 03:10:56,262
CONTROLS, WHEN WE WANT TO BUILD

5189
03:10:56,262 --> 03:10:58,898
TOOLS THAT GO AWAY FROM

5190
03:10:58,898 --> 03:11:00,733
ALGORITHM SUGGESTIONS BUT RATHER

5191
03:11:00,733 --> 03:11:01,901
HAVE INTERACTIONS WITH PATIENTS

5192
03:11:01,901 --> 03:11:04,771
TO LET THEM DECIDE AND EXPLORE

5193
03:11:04,771 --> 03:11:05,571
WHICH RECOMMENDATIONS MAKE THE

5194
03:11:05,571 --> 03:11:09,375
BEST SENSE FOR THEM, PRIVACY I

5195
03:11:09,375 --> 03:11:11,778
MENTIONED ALREADY, TRUST IN THE

5196
03:11:11,778 --> 03:11:14,180
ALGORITHMS BUT ALSO TRUST IN WHO

5197
03:11:14,180 --> 03:11:15,481
DESIGNS THE ALGORITHMS ARE

5198
03:11:15,481 --> 03:11:19,519
EXTREMELY HIGH CONCERNS FOR

5199
03:11:19,519 --> 03:11:19,886
PATIENTS.

5200
03:11:19,886 --> 03:11:20,953
AND FINALLY, INTEREST IN SAFETY,

5201
03:11:20,953 --> 03:11:23,589
I THINK HERE IS THERE'S AN

5202
03:11:23,589 --> 03:11:27,160
OPPORTUNITY FOR AI LITERACY

5203
03:11:27,160 --> 03:11:29,595
WHERE PATIENTS JUST ASSUME AI IS

5204
03:11:29,595 --> 03:11:32,198
SMARTER THAN IT CURRENTLY IS AND

5205
03:11:32,198 --> 03:11:34,200
IT THEY JUST ASSUME IF THERE'S A

5206
03:11:34,200 --> 03:11:34,934
RECOMMENDATION, IT WILL BE SAFE

5207
03:11:34,934 --> 03:11:37,804
AND I DON'T THINK THAT'S A GIVEN

5208
03:11:37,804 --> 03:11:39,305
RIGHT NOW OUR AI TECHNOLOGY AND

5209
03:11:39,305 --> 03:11:41,741
THAT'S SOMETHING ARE US AI

5210
03:11:41,741 --> 03:11:43,209
RESEARCHERS TO PAY ATTENTION TO.

5211
03:11:43,209 --> 03:11:46,145
SO AGAIN, THAT'S REALLY THE

5212
03:11:46,145 --> 03:11:47,814
ROADMAP IN VERY GENERAL FASHION,

5213
03:11:47,814 --> 03:11:53,720
BUT AI TECHNIQUES THAT ACCOUNT

5214
03:11:53,720 --> 03:11:55,221
FOR DIAGNOSIS AND HUMAN CENTERED

5215
03:11:55,221 --> 03:11:56,622
APPROACHES AND MOST IMPORTANTLY

5216
03:11:56,622 --> 03:11:56,956
TEAM SCIENCE.

5217
03:11:56,956 --> 03:11:58,925
I WANT TO THANK THE PEOPLE WHO

5218
03:11:58,925 --> 03:12:00,393
ARE WORKING ON THIS

5219
03:12:00,393 --> 03:12:03,262
ENDOMETRIOSIS WITH ME, AND ALSO

5220
03:12:03,262 --> 03:12:04,263
THE PATIENTS PARTICIPATING IN

5221
03:12:04,263 --> 03:12:12,805
OUR RESEARCH. 

5222
03:12:12,805 --> 03:12:14,307
THANK YOU.

5223
03:12:14,307 --> 03:12:19,212
>> THANK YOU DR. ELHADAD,
FOR A

5224
03:12:19,212 --> 03:12:20,046
PRESENTATION THAT'S UNDERSTUDIED

5225
03:12:20,046 --> 03:12:22,482
AND THE ROLE OF AI IN ENGAGEMENT

5226
03:12:22,482 --> 03:12:23,983
OF MULTIPLE NATIONS SO I LOOK

5227
03:12:23,983 --> 03:12:25,284
FORWARD TO THE DISCUSSION.

5228
03:12:25,284 --> 03:12:27,653
THE THIRD PRESENTATION WILL BE

5229
03:12:27,653 --> 03:12:31,858
PRESENTED BY D

5230
03:12:31,858 --> 03:12:33,292
R. KJIERSTEN FAGNAN, I HOPE

5231
03:12:33,292 --> 03:12:37,397
THAT I PRONOUNCE THAD CORRECTLY.

5232
03:12:37,397 --> 03:12:39,165
DR. FAGNAN JOINED THE DEPARTMENT

5233
03:12:39,165 --> 03:12:42,235
OF ENERGY JOINT GENOME INSTITUTE

5234
03:12:42,235 --> 03:12:47,306
IN 2012 AS A NATIONAL ENERGY

5235
03:12:47,306 --> 03:12:49,876
RESEARCH SCIENTIFIC BIOCOMPUTING

5236
03:12:49,876 --> 03:12:52,145
INFORMATICS COMPUTING

5237
03:12:52,145 --> 03:12:56,282
CONSULTANT.

5238
03:12:56,282 --> 03:13:01,587
AFTER COMPLETING A PEDASCALE AT

5239
03:13:01,587 --> 03:13:04,090
USC, AND THE NATIONAL LAB

5240
03:13:04,090 --> 03:13:04,824
CONVERTING DIVISION.

5241
03:13:04,824 --> 03:13:06,959
AS A POST DOC HER RESEARCH

5242
03:13:06,959 --> 03:13:09,095
FOCUSES ON STABLE AND ACCURATE

5243
03:13:09,095 --> 03:13:12,265
COMPUTATIONAL METHODS FOR

5244
03:13:12,265 --> 03:13:14,867
REACTING SUBSURFACE FLOWS AND

5245
03:13:14,867 --> 03:13:18,404
EVOLVE INTO SCALABLE METHODS FOR

5246
03:13:18,404 --> 03:13:20,440
SCIENTIFIC DATA ANALYSIS.

5247
03:13:20,440 --> 03:13:24,277
IN 2014, DR. FAGNAN BECAME THE

5248
03:13:24,277 --> 03:13:28,614
ENGAGEMENT LEAD FOR JGI, THE

5249
03:13:28,614 --> 03:13:31,150
JOINT GENOME INSTITUTE, WITH A

5250
03:13:31,150 --> 03:13:34,220
FOCUS ON ADAPTING JGI WORK LOADS

5251
03:13:34,220 --> 03:13:36,522
TO RUN ON SUPER COMPUTING

5252
03:13:36,522 --> 03:13:37,990
HARDWARE AND WORK CLOSELY WITH

5253
03:13:37,990 --> 03:13:41,093
STAFF TO UNDERSTAND THE DATA

5254
03:13:41,093 --> 03:13:44,764
INTENSIVE NATURE OF JGI WORK

5255
03:13:44,764 --> 03:13:45,465
FLOWS.

5256
03:13:45,465 --> 03:13:47,166
DR. FAGNAN WAS ASHES POINTED

5257
03:13:47,166 --> 03:13:51,170
CHIEF INFORMATICS OFFICER OF JGI

5258
03:13:51,170 --> 03:13:54,140
IN 2016 AND THEN HEAD OF DATA

5259
03:13:54,140 --> 03:13:57,243
SCIENCE AND INFORMATICS

5260
03:13:57,243 --> 03:13:58,911
DEPARTMENT IN 2018.

5261
03:13:58,911 --> 03:14:05,451
ALSO IN 2018, DR. FAGNAN WAS

5262
03:14:05,451 --> 03:14:09,822
PART OF THE NOBEL PRIZE WINNING

5263
03:14:09,822 --> 03:14:11,791
TEAM, WOW COMGRATTULATIONSA THE

5264
03:14:11,791 --> 03:14:12,758
SUPER COMPUTING CONFERENCE.

5265
03:14:12,758 --> 03:14:16,596
SC18 MET BY RESEARCHERS AT OAK

5266
03:14:16,596 --> 03:14:18,331
RIDGE NATIONAL LABORATORY,

5267
03:14:18,331 --> 03:14:21,234
DR. FAGNAN HAS BEEN THE

5268
03:14:21,234 --> 03:14:25,271
DISTINGUISHED SPEAKER AT IBM

5269
03:14:25,271 --> 03:14:27,673
RESEARCH IN ABUDAN WHERE SHE

5270
03:14:27,673 --> 03:14:29,175
PRESENTED WORK FOR DISTRIBUTED

5271
03:14:29,175 --> 03:14:30,910
DATA IS AND WORK FLOW

5272
03:14:30,910 --> 03:14:31,577
MANAGEMENT.

5273
03:14:31,577 --> 03:14:34,380
SHE IS CURRENTLY LEADING A

5274
03:14:34,380 --> 03:14:37,683
BIOECHO DATA INTEGRATION EFFORT

5275
03:14:37,683 --> 03:14:41,320
TO DEVELOP A GLOBAL SEARCH FOR 5

5276
03:14:41,320 --> 03:14:41,821
DOE FUNDED RESOURCES.

5277
03:14:41,821 --> 03:14:43,389
THANK YOU I AM SO LOOKING

5278
03:14:43,389 --> 03:14:44,557
FORWARD TO YOUR PRESENTATION

5279
03:14:44,557 --> 03:14:54,934
MUCH THE MIC IS YOURS.

5280
03:14:58,337 --> 03:15:00,540
>> THANK YOU, AND IT'S A
LITTLE

5281
03:15:00,540 --> 03:15:03,376
TRICKY TO LISTEN TO YOUR OWN

5282
03:15:03,376 --> 03:15:05,912
BIO, AND THANK YOU FOR THE

5283
03:15:05,912 --> 03:15:06,212
INVITATION.

5284
03:15:06,212 --> 03:15:07,380
I WILL PRESENT SOMETHING THAT'S

5285
03:15:07,380 --> 03:15:10,516
A LITTLE BIT DIFFERENT BUT I WAS

5286
03:15:10,516 --> 03:15:11,784
REALLY BLOWN AWAY BY THE LAST

5287
03:15:11,784 --> 03:15:13,185
TALK AND THINKING ABOUT WOMEN'S

5288
03:15:13,185 --> 03:15:14,987
HEALTH AND DATA IS NOT ALWAYS

5289
03:15:14,987 --> 03:15:16,789
SOMETHING WE GET TO FOCUS ON IN

5290
03:15:16,789 --> 03:15:17,723
THE DEPARTMENT OF ENERGY SO I

5291
03:15:17,723 --> 03:15:20,693
THINK YOU CAN SEE MY ENTIRE

5292
03:15:20,693 --> 03:15:21,260
SCREEN?

5293
03:15:21,260 --> 03:15:24,163
AND HOPEFULLY THIS SLIDES AND I

5294
03:15:24,163 --> 03:15:28,768
WILL GO UNTIL SOMEONE SAYS THEY

5295
03:15:28,768 --> 03:15:28,968
CAN'T.

5296
03:15:28,968 --> 03:15:32,071
SO I LINGS BIT OF BACKGROUNDOT

5297
03:15:32,071 --> 03:15:33,139
JOINT GENOME INSTITUTE AND HOW I

5298
03:15:33,139 --> 03:15:35,775
WANT TO GET INTO THIS TALK, WE

5299
03:15:35,775 --> 03:15:39,178
ARE AT LAWRENCE BURKELY NATIONAL

5300
03:15:39,178 --> 03:15:41,514
LABORATORY AND WE'RE A FACILITY

5301
03:15:41,514 --> 03:15:44,083
FUNDED BY THE DEPARTMENT OF

5302
03:15:44,083 --> 03:15:45,284
ENERGY AND OFFICE OF

5303
03:15:45,284 --> 03:15:46,519
ENVIRONMENTAL RESEARCH, WE

5304
03:15:46,519 --> 03:15:48,955
STARTED AS PART OF HUMAN GENOME

5305
03:15:48,955 --> 03:15:50,856
PROJECT AND GOT TO PIVOT TO

5306
03:15:50,856 --> 03:15:54,226
SEQUENCING ALL SORTS OF

5307
03:15:54,226 --> 03:15:54,827
ORGANISMS WITH BIOENERGY

5308
03:15:54,827 --> 03:15:56,896
RELEVANCE AND NONE OF THOSE

5309
03:15:56,896 --> 03:15:58,731
ORGANISM VS ANY EXPECTATION OF

5310
03:15:58,731 --> 03:16:01,867
PRIVACY SO OUR COMPUTING AND

5311
03:16:01,867 --> 03:16:03,736
DATA MANAGEMENT NEEDS HAVE BEEN

5312
03:16:03,736 --> 03:16:04,403
HISTORICALLY DIFFERENT, ABOUT

5313
03:16:04,403 --> 03:16:06,639
YOU WE HAVE ALMOST 300 STAFF AND

5314
03:16:06,639 --> 03:16:07,773
WE GET BETWEEN 80 AND 90 PIL

5315
03:16:07,773 --> 03:16:09,208
QULN DOLLARS IN FUNDING PER YEAR

5316
03:16:09,208 --> 03:16:12,712
TO PRODUS A TON OF DATA FOR THE

5317
03:16:12,712 --> 03:16:14,347
FOLK WHO IS PROVIDE SAMPLES TO

5318
03:16:14,347 --> 03:16:16,749
US AS WELL AS MAKING DATA

5319
03:16:16,749 --> 03:16:22,989
AVAILABLE TO OUR PRETTY LARGE

5320
03:16:22,989 --> 03:16:23,522
DATA USER COMMUNITY.

5321
03:16:23,522 --> 03:16:25,625
WE KNOW OUR DATA HAS BEEN

5322
03:16:25,625 --> 03:16:26,325
INCREDIBLY USEFUL, SOMETHING I

5323
03:16:26,325 --> 03:16:28,394
LOVE TO UNDERSTAND AND EXPLORE

5324
03:16:28,394 --> 03:16:32,131
IS HOW SOMETHING THAT WAS

5325
03:16:32,131 --> 03:16:35,101
SEQUENCED 10 OR 15 YEARS AGO

5326
03:16:35,101 --> 03:16:36,802
MIGHT HAVE APPLICATIONS IN

5327
03:16:36,802 --> 03:16:37,637
COMPLETELY DEFINITE FIELDS, SO

5328
03:16:37,637 --> 03:16:41,607
WE HAVE A REALLY GREAT IMPACT

5329
03:16:41,607 --> 03:16:42,808
ANALYST WHO'S TAKEN A BUNCH OF

5330
03:16:42,808 --> 03:16:44,977
OUR DATA AND LIVED ACROSS

5331
03:16:44,977 --> 03:16:46,812
PUBLICATIONS FOR REUSE AND WE

5332
03:16:46,812 --> 03:16:49,115
HAVE'VE GOT MORE THAN 29,000

5333
03:16:49,115 --> 03:16:51,550
STUDIES THAT HAVE LEVERAGED AI

5334
03:16:51,550 --> 03:16:54,620
DATA SO EVEN THOUGH WE'RE DOING

5335
03:16:54,620 --> 03:16:57,990
SEQUENCING OF ORGANISMS RELEVANT

5336
03:16:57,990 --> 03:16:59,058
FOR BIOENERGY AND BIOPRODUCT

5337
03:16:59,058 --> 03:17:00,192
DEVELOPMENT, THERE ARE

5338
03:17:00,192 --> 03:17:01,961
APPLICATIONS THAT GO ACROSS THE

5339
03:17:01,961 --> 03:17:04,730
SCIENCES AND 1 OF MY FIRST

5340
03:17:04,730 --> 03:17:06,232
EXAMPLES WAS THERE WAS ACTUALLY

5341
03:17:06,232 --> 03:17:10,002
A SET OF JGI MICROBES THAT GOT

5342
03:17:10,002 --> 03:17:12,972
USED IN AN ANALYSIS OF 6000

5343
03:17:12,972 --> 03:17:14,674
YEAR-OLD CHEWING GUM WHICH IS

5344
03:17:14,674 --> 03:17:17,843
KIND OF WILD AND CRAZY AND 1 OF

5345
03:17:17,843 --> 03:17:19,979
THE MICROBES THAT'S ABLE TO

5346
03:17:19,979 --> 03:17:25,084
SECRETE MANAGE NETS WAS ALSO

5347
03:17:25,084 --> 03:17:27,253
USED IN THERAPY TO TARGET CANCER

5348
03:17:27,253 --> 03:17:27,687
CELLS.

5349
03:17:27,687 --> 03:17:30,022
AND THIS JUST SHOWS THE POWER OF

5350
03:17:30,022 --> 03:17:31,424
NOD ONLY GENERATING HIGH QUALITY

5351
03:17:31,424 --> 03:17:32,825
DATA AND HIGH QUALITY REFERENCE

5352
03:17:32,825 --> 03:17:34,326
INFORMATION ABOUT A VARIETY OF

5353
03:17:34,326 --> 03:17:35,594
DIFFERENT ORGANISMS BUT ALSO

5354
03:17:35,594 --> 03:17:38,731
MAKING THAT DATA AVAILABLE FOR

5355
03:17:38,731 --> 03:17:40,099
FOLKS TO REUSE.

5356
03:17:40,099 --> 03:17:42,034
SO THERE'S BEEN, I'M SURE

5357
03:17:42,034 --> 03:17:44,503
EVERYONE HERE IS FAMILIAR WITH

5358
03:17:44,503 --> 03:17:45,838
THE DATA HUNGRY ALGORITHMS THAT

5359
03:17:45,838 --> 03:17:47,740
ARE CALLING ATTENTION TO AI

5360
03:17:47,740 --> 03:17:49,308
RESEARCH AND DIFFERENT POSSIBLE

5361
03:17:49,308 --> 03:17:49,842
SCIENTIFIC BREAKTHROUGHS.

5362
03:17:49,842 --> 03:17:53,112
SO YOU HAVE ALPHA FOLDS WHICH

5363
03:17:53,112 --> 03:17:54,046
WAS REALLY ONLY MADE POSSIBLE

5364
03:17:54,046 --> 03:17:55,781
BECAUSE HAVE YOU THE PROTEIN

5365
03:17:55,781 --> 03:17:59,518
DATA BANK AND THEN HAVE YOU THE

5366
03:17:59,518 --> 03:18:00,786
EVO AND EVO 2 WHICH HAVE

5367
03:18:00,786 --> 03:18:02,822
ACCEPTED UP ALL OF THEYQUENCE

5368
03:18:02,822 --> 03:18:04,824
DATA THEY CAN FIND TO BUILD A

5369
03:18:04,824 --> 03:18:06,425
FOUNDATION MODEL BUILT ON DNA

5370
03:18:06,425 --> 03:18:10,830
AND THEN WE HAVE OF COURSE THE

5371
03:18:10,830 --> 03:18:12,264
NLMs OR GENERATIVE AI MODELS

5372
03:18:12,264 --> 03:18:14,300
THAT ARE HELPING FOAMS DO

5373
03:18:14,300 --> 03:18:17,470
EVERYTHING FROM WRITE CODE TO

5374
03:18:17,470 --> 03:18:19,271
E-MAIL TO CREATING CRAZY IMAGES

5375
03:18:19,271 --> 03:18:20,773
THAT STILL DON'T LOOK QUITE

5376
03:18:20,773 --> 03:18:23,676
RIGHT TO ME, ANYWAY, BUT THESE

5377
03:18:23,676 --> 03:18:24,877
ALGORITHMS REQUIRE A LOT OF

5378
03:18:24,877 --> 03:18:26,645
DATA, A LOT OF CURATED DATA AND

5379
03:18:26,645 --> 03:18:28,948
A LOT OF STRUCTURE IF WE'RE

5380
03:18:28,948 --> 03:18:30,950
GOING TO ACTUALLY GET TO A POINT

5381
03:18:30,950 --> 03:18:31,917
WHERE WE TRUST THE INFORMATION

5382
03:18:31,917 --> 03:18:33,452
THAT COMES OUT OF THAT, WHICH

5383
03:18:33,452 --> 03:18:38,591
WAS MENTIONED IN THE PREVIOUS

5384
03:18:38,591 --> 03:18:38,791
TALK.

5385
03:18:38,791 --> 03:18:40,459
I HAPPEN TO SEE THIS QUOTE WHICH

5386
03:18:40,459 --> 03:18:41,961
I WAS WALKING THROUGH THIS

5387
03:18:41,961 --> 03:18:46,499
BUILDING AND IT REALLY RESONATED

5388
03:18:46,499 --> 03:18:48,334
WITH ME KIND OF WHAT WE'RE

5389
03:18:48,334 --> 03:18:48,868
DEALING WITH.

5390
03:18:48,868 --> 03:18:50,603
SO IN THE STATE OF OUR DATA

5391
03:18:50,603 --> 03:18:54,340
SYSTEMS, WE ARE DROWNING

5392
03:18:54,340 --> 03:18:55,007
INFORMATIONALLY, STARVING PER

5393
03:18:55,007 --> 03:18:56,909
WISDOM, WE HAVE SO MUCH DATA

5394
03:18:56,909 --> 03:18:57,743
FLOATING AROUND IN DIFFERENT

5395
03:18:57,743 --> 03:19:00,780
SOURCES, THERE ARE MORE THAN

5396
03:19:00,780 --> 03:19:02,348
3000 DIFFERENT DISTINCT

5397
03:19:02,348 --> 03:19:07,086
BIOLOGICAL DATA RESOURCES THAT

5398
03:19:07,086 --> 03:19:07,520
EXIST.

5399
03:19:07,520 --> 03:19:10,923
AND THAT NUMBER IS PROBABLY

5400
03:19:10,923 --> 03:19:11,757
GROWING OR FLUCTUATING, AND

5401
03:19:11,757 --> 03:19:14,794
THERE ARE SOME THAT ARE BUILT BY

5402
03:19:14,794 --> 03:19:16,862
STUDENTS THAT LEAVE THE LAB BUT

5403
03:19:16,862 --> 03:19:18,130
IT DOESN'T CHANGE THE FACT THAT

5404
03:19:18,130 --> 03:19:20,199
IT'S EASY TO CREATE A DATA

5405
03:19:20,199 --> 03:19:22,301
PORTAL, AND EASY TO POST DATA UP

5406
03:19:22,301 --> 03:19:24,270
ON THE INTERNET, WHAT'S

5407
03:19:24,270 --> 03:19:25,471
CHALLENGING IS MAKING IT

5408
03:19:25,471 --> 03:19:25,805
ACCESSIBLE.

5409
03:19:25,805 --> 03:19:26,972
AND THE CONCEPT OF PEOPLE BEING

5410
03:19:26,972 --> 03:19:28,808
ABLE TO PUT TOGETHER THE RIGHT

5411
03:19:28,808 --> 03:19:29,775
INFORMATION AT THE RIGHT TIME

5412
03:19:29,775 --> 03:19:31,844
AND TO THINK CRITICALLY ABOUT

5413
03:19:31,844 --> 03:19:34,013
IT, I THINK, THAT'S WHAT WE WANT

5414
03:19:34,013 --> 03:19:36,081
TO ENABLE FOR OUR SCIENTIFIC

5415
03:19:36,081 --> 03:19:37,483
COMMUNITIES, AT A USER FACILITY,

5416
03:19:37,483 --> 03:19:39,785
THIS IS PART OF OUR MISSION,

5417
03:19:39,785 --> 03:19:41,153
LIKE, HOW DO WE CREATE THE

5418
03:19:41,153 --> 03:19:42,555
SYSTEMS AND LET FOLKS DISCOVER

5419
03:19:42,555 --> 03:19:43,823
AND WORK WITH AND UNDERSTAND

5420
03:19:43,823 --> 03:19:46,225
DATA SO THAT THEY CAN THINK

5421
03:19:46,225 --> 03:19:50,196
CRITICALLY ABOUT IT AND ADVANCE

5422
03:19:50,196 --> 03:19:50,529
SCIENCE.

5423
03:19:50,529 --> 03:19:51,997
I JUST WAS SO SURPRISED THAT

5424
03:19:51,997 --> 03:19:54,767
I'VE BEEN IN THIS BUILDING FOR A

5425
03:19:54,767 --> 03:19:55,968
FEW YEARS AND THIS IS THE FIRST

5426
03:19:55,968 --> 03:19:58,871
TIME I STOPPED AND NOTICED AND

5427
03:19:58,871 --> 03:19:59,638
READ THE QUOTE.

5428
03:19:59,638 --> 03:20:10,049
IT FELT REALLY RELEVANT.

5429
03:20:10,983 --> 03:20:13,219
-- RESEARCH AND SO THERE ARE A

5430
03:20:13,219 --> 03:20:14,920
LOT OF ACRONYMS ON THE SLIDE

5431
03:20:14,920 --> 03:20:17,923
THAT I WILL JUST HIGHLIGHT, THE

5432
03:20:17,923 --> 03:20:19,425
JOINT GENOME INSTITUTE, THE

5433
03:20:19,425 --> 03:20:21,327
ADVANCES OF MOLECULAR SCIENCES

5434
03:20:21,327 --> 03:20:24,396
LABORATORY, THESE ARE 2 USER

5435
03:20:24,396 --> 03:20:25,598
FACILITIES THAT GENERATE

5436
03:20:25,598 --> 03:20:26,665
MULTIOMICS DATA TYPES AND ALSO

5437
03:20:26,665 --> 03:20:28,767
PRODUCES A LOT OF IMAGING DATA

5438
03:20:28,767 --> 03:20:30,302
AND THEN WE HAVE THE DAILY

5439
03:20:30,302 --> 03:20:32,137
SYSTEMS KNOWLEDGE BASE AND NMDC

5440
03:20:32,137 --> 03:20:35,908
AND AN EFFORT TO STANDARDIZE

5441
03:20:35,908 --> 03:20:37,076
MICROBIOME DATA, WHICH THEY'VE

5442
03:20:37,076 --> 03:20:39,278
DONE A REALLY AMAZING JOB

5443
03:20:39,278 --> 03:20:41,580
CREATING A NEW COMP REHAPPENSIVE

5444
03:20:41,580 --> 03:20:43,415
DATA MODEL THAT LINKS

5445
03:20:43,415 --> 03:20:44,350
ENVIRONMENT INFORMATION THAT

5446
03:20:44,350 --> 03:20:46,952
LINKS TO GENOMIC AND MULTIOMIC

5447
03:20:46,952 --> 03:20:48,954
WHICH IS REALLY USEFUL DEPENDING

5448
03:20:48,954 --> 03:20:50,022
ON THE HYPOTHESIS SOMEBODY MIGHT

5449
03:20:50,022 --> 03:20:55,294
WANT TO EXPLORE AND THEN ESI IS

5450
03:20:55,294 --> 03:20:57,229
A DIFFERENT FOR COMPLEX

5451
03:20:57,229 --> 03:20:58,464
MEASUREMENTS SO WHAT WE'RE

5452
03:20:58,464 --> 03:21:01,867
TRYING TO DO IS ADDRESS A

5453
03:21:01,867 --> 03:21:03,702
PINPOINT FOR A COMMUNITY WHERE

5454
03:21:03,702 --> 03:21:07,106
YOU CAN'T NECESSARILY FIND THE

5455
03:21:07,106 --> 03:21:08,974
DATA ACROSS THESE SYSTEMS FROM 1

5456
03:21:08,974 --> 03:21:09,241
PLACE.

5457
03:21:09,241 --> 03:21:11,210
IT'S SIMILAR IN SPIRIT TO THE

5458
03:21:11,210 --> 03:21:13,245
3000 DIFFERENT DATA RESOURCES,

5459
03:21:13,245 --> 03:21:15,414
EXCEPT THESE 5 RESOURCES ARE ALL

5460
03:21:15,414 --> 03:21:17,583
FUNDED BY THE SAME ENTITY AND IN

5461
03:21:17,583 --> 03:21:21,253
PRINCIPLE WE SHOULD BE ABLE TO

5462
03:21:21,253 --> 03:21:24,123
TACKLE THIS PROBLEM.

5463
03:21:24,123 --> 03:21:26,892
IT'S NOT, YOU KNOW, IT'S A VERY

5464
03:21:26,892 --> 03:21:28,327
NATURAL DEVELOPMENT, THERE ARE A

5465
03:21:28,327 --> 03:21:31,797
LOT OF SOCIOLOGICAL LOGICAL LAWS

5466
03:21:31,797 --> 03:21:32,831
THAT DESCRIBE HOW INFRANCIS

5467
03:21:32,831 --> 03:21:34,800
COLLINS SPHRUCTURE GETS

5468
03:21:34,800 --> 03:21:38,804
DEVELOPED ACROSS OR WITHIN AN

5469
03:21:38,804 --> 03:21:42,441
ORGANIZATION AND ALIGNS TO THE

5470
03:21:42,441 --> 03:21:49,315
ORG CHART, AND SO IF I WANT TO

5471
03:21:49,315 --> 03:21:51,050
USE DATA I HAVE TO SEND A

5472
03:21:51,050 --> 03:21:52,251
DIFFERENT QUERY TO EACH OF THESE

5473
03:21:52,251 --> 03:21:53,719
RESOURCES AND THEN I WILL GET

5474
03:21:53,719 --> 03:21:55,854
BACK SOMETHING IN A COMPLETELY

5475
03:21:55,854 --> 03:21:57,222
DIFFERENT STRUCTURE, SO, IT'S

5476
03:21:57,222 --> 03:21:59,191
ALL GOING TO BE DIFFERENT, THE

5477
03:21:59,191 --> 03:22:01,393
MODEL LIKE THE UNDERLYING SCHEME

5478
03:22:01,393 --> 03:22:02,895
AUSHED LYING DATA

5479
03:22:02,895 --> 03:22:04,363
REPRESENTATION, WHICH I'M

5480
03:22:04,363 --> 03:22:04,997
REPRESENTING WITH THESE AT THE

5481
03:22:04,997 --> 03:22:06,098
TIME RISK ASSESSMENTS PLOOKS

5482
03:22:06,098 --> 03:22:07,833
WILL BE DIFFERENT EVEN IF I'M

5483
03:22:07,833 --> 03:22:10,035
CLEARING, FOR THE SAME TYPES OF

5484
03:22:10,035 --> 03:22:12,571
INFORMATION. 

5485
03:22:12,571 --> 03:22:15,207
SO IT COULD BE CLEARING ACROSS

5486
03:22:15,207 --> 03:22:16,475
THESE DIFFERENT RESOURCES BUT I

5487
03:22:16,475 --> 03:22:18,210
WILL STILL GET BACK A DIFFERENT

5488
03:22:18,210 --> 03:22:18,711
DATA STRUCTURE.

5489
03:22:18,711 --> 03:22:20,913
AND THEN, YOU KNOW THE WORK, THE

5490
03:22:20,913 --> 03:22:22,414
INTEGRATION WORK THAT IS A

5491
03:22:22,414 --> 03:22:24,950
SCIENTIST NEEDS TO DO IS VERY

5492
03:22:24,950 --> 03:22:26,218
TIME CONSUMING, HOW DO I PUT

5493
03:22:26,218 --> 03:22:30,189
THESE BLOCKS TOGETHER, IN A WAY

5494
03:22:30,189 --> 03:22:31,156
THAT LEADS TO SOMETHING USEFUL

5495
03:22:31,156 --> 03:22:32,324
FOR THE QUESTION I HAVE, HOW

5496
03:22:32,324 --> 03:22:34,159
DOES IT HELP ME UNDERSTAND THE

5497
03:22:34,159 --> 03:22:36,962
GAPS IN THE DATA OR WHERE THINGS

5498
03:22:36,962 --> 03:22:39,732
ARE MISALIGNED AND THAT'S

5499
03:22:39,732 --> 03:22:40,799
REALLY, HOPEFULLY, THIS IS

5500
03:22:40,799 --> 03:22:42,034
REALLY THE WORK, THE SCIENTIFIC

5501
03:22:42,034 --> 03:22:43,702
WORK THAT'S BEEN DONE.

5502
03:22:43,702 --> 03:22:46,638
SO THEY'RE COMBINING THAT DATA,

5503
03:22:46,638 --> 03:22:48,507
TO GET THERE TO ADDRESS THEIR

5504
03:22:48,507 --> 03:22:49,775
HYPOTHESIS AND SO OUR INITIAL

5505
03:22:49,775 --> 03:22:52,411
GOAL WAS TO START WITH A COMMON

5506
03:22:52,411 --> 03:22:53,479
SEARCH ENTRY POINT THROUGH

5507
03:22:53,479 --> 03:22:54,847
ACCESSING DATA ACROSS ALL OF

5508
03:22:54,847 --> 03:22:55,481
THESE RESOURCES.

5509
03:22:55,481 --> 03:23:00,619
SO THEY CAN SUBMIT THE SAME

5510
03:23:00,619 --> 03:23:01,987
QUERY, AND GET INFORMATION BACK,

5511
03:23:01,987 --> 03:23:03,389
THE INFORMATION IS STILL GOING

5512
03:23:03,389 --> 03:23:04,823
TO BE IN THOSE DIFFERENT SHAPED

5513
03:23:04,823 --> 03:23:06,158
CONTROLLER OF BANKS BUT THIS IS

5514
03:23:06,158 --> 03:23:07,993
STILL HELPFUL FOR AT LEAST

5515
03:23:07,993 --> 03:23:10,863
KNOWING AND DISCOVERING WHAT

5516
03:23:10,863 --> 03:23:11,764
DATA IS AVAILABLE.

5517
03:23:11,764 --> 03:23:12,731
WE'VE DONE USER RESEARCH AND

5518
03:23:12,731 --> 03:23:14,166
THIS WAS AS A MENTIONED IN THE

5519
03:23:14,166 --> 03:23:16,135
PREVIOUS TALK, I THINK THIS IS

5520
03:23:16,135 --> 03:23:18,537
ABSOLUTELY CRITICAL WHEN YOU ARE

5521
03:23:18,537 --> 03:23:19,705
BUILDING INFRASTRUCTURE OR

5522
03:23:19,705 --> 03:23:20,839
BUILDING AERER SOURCE FOR THE

5523
03:23:20,839 --> 03:23:21,573
SCIENTIFIC COMMUNITY IS THAT YOU

5524
03:23:21,573 --> 03:23:22,775
PUT THE FOLK WHAT'S ARE GOING TO

5525
03:23:22,775 --> 03:23:24,410
USE IT AT THE HEART OF YOUR

5526
03:23:24,410 --> 03:23:24,643
PLAN.

5527
03:23:24,643 --> 03:23:28,714
SO THIS IS A REPRESENTATION ON

5528
03:23:28,714 --> 03:23:30,115
THE RIGHT HERE OF THE DATA LIFE

5529
03:23:30,115 --> 03:23:31,617
PSYCHE AND HE WILL DIFFERENT

5530
03:23:31,617 --> 03:23:33,118
ASSPECS THAT WEB CONNECTED AS A

5531
03:23:33,118 --> 03:23:35,087
USER FACILITY NEED TO KEEP IN

5532
03:23:35,087 --> 03:23:37,656
MIND TR MAKING SURE THE DATA IS

5533
03:23:37,656 --> 03:23:38,624
HIGHLY USE BELIEVABLE, NOT JUST

5534
03:23:38,624 --> 03:23:40,559
TO THE PERSON PROVIDING THE

5535
03:23:40,559 --> 03:23:42,394
SAMPLE BUT TO OTHER MEMBERS OF

5536
03:23:42,394 --> 03:23:46,265
THE SCIENTIFIC COMMUNITY AND WE

5537
03:23:46,265 --> 03:23:47,666
NOTICED A FEW DIFFERENT TRENDS,

5538
03:23:47,666 --> 03:23:49,268
WHEN WE SPOKE WITH THE USER

5539
03:23:49,268 --> 03:23:50,569
COMMUNITY ABOUT WHAT THEY WERE

5540
03:23:50,569 --> 03:23:52,504
DOING WITH THEIR DATA AND 1 IS

5541
03:23:52,504 --> 03:23:54,173
THAT THEY ARE GENERATING MORE

5542
03:23:54,173 --> 03:23:55,541
DATA, AND SPENDING INCREASING

5543
03:23:55,541 --> 03:23:58,577
RESOURCES ON DATA MANAGEMENT AND

5544
03:23:58,577 --> 03:23:59,311
BUILDING THEIR OWN

5545
03:23:59,311 --> 03:24:00,679
INFRASTRUCTURE, SO IN THE FUTURE

5546
03:24:00,679 --> 03:24:02,915
THAT 300 MIGHT GO TO 4000, 5000

5547
03:24:02,915 --> 03:24:04,650
IF WE'RE NOT -- YOU ACTUALLY

5548
03:24:04,650 --> 03:24:06,151
DON'T KNOW WHAT THE MAXIMUM

5549
03:24:06,151 --> 03:24:08,153
NUMBER MIGHT BE BUT THIS NUMBER

5550
03:24:08,153 --> 03:24:09,421
OF DISCONNECTED DATA RESOURCES

5551
03:24:09,421 --> 03:24:13,192
IS NOT SLOWING DOWN.

5552
03:24:13,192 --> 03:24:16,462
IT'S NOT, THERE'S NO COALESCE

5553
03:24:16,462 --> 03:24:17,529
ENSEL, IT'S VERY EASY THAT YOU

5554
03:24:17,529 --> 03:24:19,264
HAVE A NEW DATA RESOURCE

5555
03:24:19,264 --> 03:24:21,100
AVAILABLE, OR HAVE A RESULT

5556
03:24:21,100 --> 03:24:25,304
THAT'S NEW DATA PORTAL, AND IT

5557
03:24:25,304 --> 03:24:26,839
TAKES RESOURCES TO BUILD IT BUT

5558
03:24:26,839 --> 03:24:28,440
THEN IT TAIBS EVEN MORE

5559
03:24:28,440 --> 03:24:31,076
RESOURCES TO MAINTAIN IT, SO

5560
03:24:31,076 --> 03:24:32,010
THEY'RE RESOURCING IT BUT THEN

5561
03:24:32,010 --> 03:24:34,079
OVER TIME THIS IS GOING TO GROW.

5562
03:24:34,079 --> 03:24:36,415
SO THEY'RE PAYING FOR SOFTWARE,

5563
03:24:36,415 --> 03:24:37,783
SOFTWARE DEVELOP AM, ALLOCATING

5564
03:24:37,783 --> 03:24:39,318
UP TO 10% OF GRANTS TO COVER

5565
03:24:39,318 --> 03:24:41,453
STAFF THAT ARE JUST ENGAGED IN

5566
03:24:41,453 --> 03:24:43,589
THESE DATA MANAGEMENT

5567
03:24:43,589 --> 03:24:43,922
ACTIVITIES.

5568
03:24:43,922 --> 03:24:45,557
AND THEY ARE A COUPLE DIFFERENT

5569
03:24:45,557 --> 03:24:46,725
REASONS FOR THIS, SOMETIMES THE

5570
03:24:46,725 --> 03:24:49,461
DAILY BASIS THEA ITSELF DOESN'T

5571
03:24:49,461 --> 03:24:51,530
HAVE ANOTHER HOME, SO FOR

5572
03:24:51,530 --> 03:24:53,632
PROTEIN STRUCTURES, YOU HAVE

5573
03:24:53,632 --> 03:24:56,502
PBB, FOR MASS SPEC., YOU MIGHT

5574
03:24:56,502 --> 03:24:58,237
USE MASSIVE, FOR PROTEOMICS,

5575
03:24:58,237 --> 03:25:01,240
HAVE YOU PRIDE, ASSUMING PEOPLE

5576
03:25:01,240 --> 03:25:02,274
KNOW THAT'S REPOSITORIES EXIST,

5577
03:25:02,274 --> 03:25:04,743
AND 1 FORT BEST RESOURCES FOR US

5578
03:25:04,743 --> 03:25:06,678
AS BEEN THE SEQUENCE READ

5579
03:25:06,678 --> 03:25:10,048
ARCHIVE RUN BY NIH, THE NATIONAL

5580
03:25:10,048 --> 03:25:12,451
LIBRARY OF MEDICINE, FECS HERE

5581
03:25:12,451 --> 03:25:14,753
ARE PROBABLY FAMILIAR WITH IT

5582
03:25:14,753 --> 03:25:16,355
AND A LONG TIME AGO EVERYBODY

5583
03:25:16,355 --> 03:25:17,990
GOT TOGETHER AND DECIDED THAT

5584
03:25:17,990 --> 03:25:19,958
WAS THE POLICE FOR SEQUENCE DATA

5585
03:25:19,958 --> 03:25:22,094
TO LAND AND IT WOULD HAVE THE

5586
03:25:22,094 --> 03:25:22,828
IDENTIFIERS PEOPLED NEEDED TO

5587
03:25:22,828 --> 03:25:25,264
FIND THAT DATA AGAIN AND IT

5588
03:25:25,264 --> 03:25:27,032
SEARCHES THIS AMAZING RESOURCE

5589
03:25:27,032 --> 03:25:27,499
FOR THE COMMUNITY.

5590
03:25:27,499 --> 03:25:29,001
ABOUT YOU WHEN YOU HAVE

5591
03:25:29,001 --> 03:25:29,801
SOMETHING THAT LEVERAGES

5592
03:25:29,801 --> 03:25:31,003
SEQUENCE DATA BUT THEN BUILDS ON

5593
03:25:31,003 --> 03:25:34,306
TOP OF IT, IF YOU HAVE YOU KNOW

5594
03:25:34,306 --> 03:25:36,375
YOUR OWN ANNOTATIONS OR YOUR OWN

5595
03:25:36,375 --> 03:25:38,810
ASSEMBLIES OR YOUR OWN

5596
03:25:38,810 --> 03:25:40,812
METAGENOMIC BINS, THERE ISN'T A

5597
03:25:40,812 --> 03:25:42,447
NATIONAL REPOSITORY FOR THOSE

5598
03:25:42,447 --> 03:25:43,749
DATA ENTITIES, SO FOLKS ARE

5599
03:25:43,749 --> 03:25:44,816
RESPONDING BECAUSE THEY WANT TO

5600
03:25:44,816 --> 03:25:45,984
MAKE THAT DATA AVAILABLE BUT

5601
03:25:45,984 --> 03:25:50,689
THEY'RE BUILDING THEIR OWN, AND

5602
03:25:50,689 --> 03:25:58,564
WELL IS A HUGE WAY FOR FOLKS TO

5603
03:25:58,564 --> 03:25:59,731
AUTOMATE.

5604
03:25:59,731 --> 03:26:02,901
NO 1 LIKES TO DO THE BOOK

5605
03:26:02,901 --> 03:26:04,036
KEEPING, IT'S COMPLEX,

5606
03:26:04,036 --> 03:26:05,771
LEVERAGING A MET DATA STANDARD,

5607
03:26:05,771 --> 03:26:07,306
IT'S VERY TIME CONSUMING AND NOT

5608
03:26:07,306 --> 03:26:09,541
SOMETHING THAT NECESSARILY HELPS

5609
03:26:09,541 --> 03:26:10,375
WITH YOUR SCIENTIFIC

5610
03:26:10,375 --> 03:26:12,211
EXPLORATION, BUT IT HELPS

5611
03:26:12,211 --> 03:26:13,946
SOMEBODY ELSE USE YOUR DATA AND

5612
03:26:13,946 --> 03:26:16,415
SO THERE'S A BIT OF AN INCENTIVE

5613
03:26:16,415 --> 03:26:18,784
TO MISS MATCH THERE AND IT'S A

5614
03:26:18,784 --> 03:26:20,652
PRETTY TEDIOUS PROCESS AND I

5615
03:26:20,652 --> 03:26:23,889
ALREADY TO THIS, THERE ARE GAPS

5616
03:26:23,889 --> 03:26:25,190
IN THE PREPOSITORY

5617
03:26:25,190 --> 03:26:25,991
INFRASTRUCTURE, SO WHAT WE'RE

5618
03:26:25,991 --> 03:26:27,059
BUILDING RIGHT NOW IS SOMETHING

5619
03:26:27,059 --> 03:26:29,394
TO HELP US SEARCH, IT'S MORE OF

5620
03:26:29,394 --> 03:26:39,905
A HARMONIZATION EFFORT THAN A

5621
03:26:40,239 --> 03:26:43,175
DATA INTEGRATION EFFORT.

5622
03:26:43,175 --> 03:26:46,378
BUILDING THIS SEARCH TOOLING,

5623
03:26:46,378 --> 03:26:47,479
HELPS US ACROSS OUR MODEL.

5624
03:26:47,479 --> 03:26:49,448
AND THE CORE ISSUE THAT FOLKS

5625
03:26:49,448 --> 03:26:51,717
ARE RUNNING INTO WITH METADATA

5626
03:26:51,717 --> 03:26:53,452
RESUES ARE METADAILY BASIS THEA,

5627
03:26:53,452 --> 03:26:54,519
THEY'RE NOT HARMONIZED AND

5628
03:26:54,519 --> 03:26:55,420
THINGS ARE DIFFERENT CROSS

5629
03:26:55,420 --> 03:27:02,160
SYSTEMS AND WITHOUT THIS DATA

5630
03:27:02,160 --> 03:27:02,961
HARMONIZATION EFFORT, THINGS

5631
03:27:02,961 --> 03:27:06,198
WILL CONTINUE TO BE ISOLATED AND

5632
03:27:06,198 --> 03:27:07,699
NOT INGRATABLE AND THAT LIMITS

5633
03:27:07,699 --> 03:27:10,369
OUR ABILITY TO USE THOSE DATA

5634
03:27:10,369 --> 03:27:11,670
HUNGRY ALGORITHMS OR TO BUILD

5635
03:27:11,670 --> 03:27:14,306
NIEW MODELS THAT ACTUALLY

5636
03:27:14,306 --> 03:27:15,507
LEVERAGE OUR SCIENTIFIC DATA.

5637
03:27:15,507 --> 03:27:17,843
SO AS PART OF OUR EFFORT WE

5638
03:27:17,843 --> 03:27:20,812
CREATED THIS FOUNDATIONAL SHARED

5639
03:27:20,812 --> 03:27:22,447
DATA MODEL, WE LOOKED ACROSS ALL

5640
03:27:22,447 --> 03:27:24,950
5 OF OUR RESOURCES AND WE FOUND

5641
03:27:24,950 --> 03:27:29,388
VERY FEW TERMS IN COMMON, THINGS

5642
03:27:29,388 --> 03:27:31,290
WERE COMMON THOUGH, SO WE USED

5643
03:27:31,290 --> 03:27:33,825
THOSE TO BUILD A MAP TO SHOW TO

5644
03:27:33,825 --> 03:27:37,329
OUR COMMUNITY ACTUALLY IF

5645
03:27:37,329 --> 03:27:39,865
THEY'RE INTERESTED IN NOT JUST

5646
03:27:39,865 --> 03:27:41,967
GENOMICS DATA FROM THE JGI, BUT

5647
03:27:41,967 --> 03:27:43,702
THEY'RE INTERESTED IN SAMPLES

5648
03:27:43,702 --> 03:27:45,003
THAT HAVE MULTIOMICS

5649
03:27:45,003 --> 03:27:45,737
MEASUREMENTS, OUR PARTNER VS

5650
03:27:45,737 --> 03:27:47,005
TAKEN A LOT OF THOSE

5651
03:27:47,005 --> 03:27:48,273
MEASUREMENTS AND IF THEY'RE

5652
03:27:48,273 --> 03:27:50,042
INTERESTED IN NOT ONLY

5653
03:27:50,042 --> 03:27:53,679
MULTIOMICS DATA BUT ALSO,

5654
03:27:53,679 --> 03:27:54,613
GEOCHEMICAL SENSORS OR OTHER

5655
03:27:54,613 --> 03:27:55,547
MEASUREMENTS THAT WE HAVE THAT

5656
03:27:55,547 --> 03:27:58,950
DATA AS WELL AND SO THIS WAS AN

5657
03:27:58,950 --> 03:28:00,485
XERICIZE TO REALLY SHOW THAT WE

5658
03:28:00,485 --> 03:28:02,187
COULD BUILD THESE CONNECTIONS,

5659
03:28:02,187 --> 03:28:03,588
WE COULD BUILD THE SHARED

5660
03:28:03,588 --> 03:28:07,626
UNDERSTANDING OF WHAT EXISTS AND

5661
03:28:07,626 --> 03:28:09,494
THERE'S PROGRESS ON OUR INITIAL

5662
03:28:09,494 --> 03:28:10,929
SEARCH PROJECT CREATED THIS

5663
03:28:10,929 --> 03:28:12,230
GRAPHICAL ENTRY POINT TO THE

5664
03:28:12,230 --> 03:28:13,865
DATA AND THEN WE DO HAVE A

5665
03:28:13,865 --> 03:28:15,734
VERSION 0 OF THE API THAT WE

5666
03:28:15,734 --> 03:28:16,535
BUILD TOGETHER.

5667
03:28:16,535 --> 03:28:18,704
AND SO THESE COMPLEX RESPONSES

5668
03:28:18,704 --> 03:28:20,472
WE GET BACK ARE STILL MEANS THAT

5669
03:28:20,472 --> 03:28:23,108
A USER HAS TO SPEND TIME

5670
03:28:23,108 --> 03:28:25,177
HARMONIZING THAT INFORMATION AND

5671
03:28:25,177 --> 03:28:27,079
INTEGRATING IT THEMSELVES, BUT

5672
03:28:27,079 --> 03:28:28,480
WE'RE KREASESSING THAT FIRST

5673
03:28:28,480 --> 03:28:30,649
STEP IN FIGURING OUT HOW DO THAT

5674
03:28:30,649 --> 03:28:30,949
TOGETHER.

5675
03:28:30,949 --> 03:28:31,917
AND THIS IS IMPORTANT, WE'RE

5676
03:28:31,917 --> 03:28:33,452
THINKING ABOUT THE FUTURE OF

5677
03:28:33,452 --> 03:28:35,654
BEING ABLE TO USE LARGE LANGUAGE

5678
03:28:35,654 --> 03:28:36,922
MODELS AND AI AGENTS.

5679
03:28:36,922 --> 03:28:40,192
I THINK THOSE ARE EVERYWHERE.

5680
03:28:40,192 --> 03:28:43,161
RIGHT NOW YOU CAN COMBINE DATA

5681
03:28:43,161 --> 03:28:46,331
FROM DIFFERENT SOURCES THROUGH

5682
03:28:46,331 --> 03:28:47,432
THE APIs THAT ARE MADE

5683
03:28:47,432 --> 03:28:48,867
AVAILABLE BUT YOU HAVE TO BUILD

5684
03:28:48,867 --> 03:28:49,935
THE KIND OF STRUCTURE THAT SO

5685
03:28:49,935 --> 03:28:53,438
THAT YOU KEEP A HUMAN IN THE

5686
03:28:53,438 --> 03:28:57,309
LOOP TO ERROR-CORRECT.

5687
03:28:57,309 --> 03:28:59,010
AND SO, YOU KNOW, THIS IS JUST A

5688
03:28:59,010 --> 03:29:00,645
HIGH LEVEL, SORT OF AN AGENT

5689
03:29:00,645 --> 03:29:03,815
MIGHT DECIDE THIS IS THE

5690
03:29:03,815 --> 03:29:08,754
IDEALIZED WAY TO PUT THE  TETRIS

5691
03:29:08,754 --> 03:29:10,555
PLOKS TOGETHER, BUT MAYBE THE

5692
03:29:10,555 --> 03:29:12,124
OWNER WANTED SOMETHING DIFFERENT

5693
03:29:12,124 --> 03:29:13,492
BECAUSE MAYBE IT MAKES SENSE FOR

5694
03:29:13,492 --> 03:29:15,127
THE PURPLE TO ALIEB TO THE BLUE

5695
03:29:15,127 --> 03:29:16,795
OR WHATEVER, IT'S A MENTAL MODEL

5696
03:29:16,795 --> 03:29:18,397
BUT WITH A HUMAN WORKING WITH

5697
03:29:18,397 --> 03:29:20,399
THE AGENT WHO CAN CONSTRUCK

5698
03:29:20,399 --> 03:29:22,367
THESE MODELS TOGETHER AND CAN --

5699
03:29:22,367 --> 03:29:26,738
THE QUESTION BECOMES CAN WE

5700
03:29:26,738 --> 03:29:28,340
ACTUALLY REDUCE THAT TIME TO A

5701
03:29:28,340 --> 03:29:29,641
USER TO UNDERSTAND AND STRUCTURE

5702
03:29:29,641 --> 03:29:30,942
THE RIGHT DATA MODELS TO ADDRESS

5703
03:29:30,942 --> 03:29:34,379
THE QUESTION OF INTEREST?

5704
03:29:34,379 --> 03:29:36,314
AND THIS IS THE INFRASTRUCTURE

5705
03:29:36,314 --> 03:29:37,783
THAT WE'RE PUTTING IN PLACE

5706
03:29:37,783 --> 03:29:40,786
ACROSS OUR 5 RESOURCES TO ENABLE

5707
03:29:40,786 --> 03:29:41,319
THIS.

5708
03:29:41,319 --> 03:29:42,988
SO THIS A COMPLEX DEC, IF THERE

5709
03:29:42,988 --> 03:29:45,190
ARE QUESTIONS I AM HAPPY TO TALK

5710
03:29:45,190 --> 03:29:50,395
ABOUT IT, BUT KEY IDEA IS THAT

5711
03:29:50,395 --> 03:29:51,830
WE'RE TAKING THIS FAIR SEARCH

5712
03:29:51,830 --> 03:29:53,064
WE'RE BUILDING AND WE'RE

5713
03:29:53,064 --> 03:29:55,167
BUILDING TO CROSS RESOURCE DATA

5714
03:29:55,167 --> 03:29:57,335
MODEL CATALOG, SO THROUGH THAT

5715
03:29:57,335 --> 03:29:58,703
ENTRY POINT HAVE YOU AWARENESS

5716
03:29:58,703 --> 03:30:00,539
OF WHAT EXISTS ACROSS THESE

5717
03:30:00,539 --> 03:30:04,276
DIFFERENT B. E. R. RESOURCES,

5718
03:30:04,276 --> 03:30:07,279
BUT THESE DIFFERENT BRE

5719
03:30:07,279 --> 03:30:09,681
RESOURCES DON'T HAVE TO ONLY

5720
03:30:09,681 --> 03:30:11,750
SUPPORT THIS CATALOG, SO YOU CAN

5721
03:30:11,750 --> 03:30:13,385
MAKE TAIN THESE SPECIFIC PROJECT

5722
03:30:13,385 --> 03:30:14,686
SCHEMAS, YOU CAN MAINTAIN THE

5723
03:30:14,686 --> 03:30:15,987
HISTORY, CAN YOU MAINTAIN THE

5724
03:30:15,987 --> 03:30:17,522
SILOS IF YOU WOULD LIKE TO, AND

5725
03:30:17,522 --> 03:30:20,125
THE WAY YOU DO THE HARMONIZATION

5726
03:30:20,125 --> 03:30:23,361
IS THROUGH THE CROSS RESOURCE

5727
03:30:23,361 --> 03:30:24,729
DATA MODEL CATALOG, SO WE BUILD

5728
03:30:24,729 --> 03:30:26,364
THE SHARED MODEL TOGETHER, IT

5729
03:30:26,364 --> 03:30:28,333
HAS AN UNDERSTANDING OF NOT ONLY

5730
03:30:28,333 --> 03:30:29,835
WHAT EXISTS IN THESE DIFFERENT

5731
03:30:29,835 --> 03:30:31,069
RESOURCES BUT ALSO THESE ORANGE

5732
03:30:31,069 --> 03:30:32,838
DASH LINES THAT SHOW THE

5733
03:30:32,838 --> 03:30:37,809
CONNECTIONS ACROSS THEM, SO THE

5734
03:30:37,809 --> 03:30:41,213
CANONICLE MODEL THOSE SHOWING

5735
03:30:41,213 --> 03:30:43,415
LONG, AND WOULD BE CAPTURED IN

5736
03:30:43,415 --> 03:30:45,317
THIS CATALOG AND THE REASON IT

5737
03:30:45,317 --> 03:30:50,689
IS BENEFICIAL IS BECAUSE WE CAN

5738
03:30:50,689 --> 03:30:52,257
TAKE OUR HANDFUL OF PORTALS, WE

5739
03:30:52,257 --> 03:30:55,026
ARE PART OF THE PROBLEM, WE HAVE

5740
03:30:55,026 --> 03:30:57,696
3000 BUT THEY PROVIDED VALUE TO

5741
03:30:57,696 --> 03:30:58,296
THE COMMUNITY OVER DECADE

5742
03:30:58,296 --> 03:30:58,864
SPECIALIZATION OF SPECIFIC

5743
03:30:58,864 --> 03:30:59,898
ENDOTHELIAL WE DON'T WANT THOSE

5744
03:30:59,898 --> 03:31:02,634
TO GO AWAY WHILE WE TRY TO MAKE

5745
03:31:02,634 --> 03:31:04,603
OUR DATA MORE AVAILABLE TO AI

5746
03:31:04,603 --> 03:31:04,836
AGENTS.

5747
03:31:04,836 --> 03:31:15,313
SO WHAT WE'VE DONE AND WHAT

5748
03:31:17,415 --> 03:31:24,256
WE'RE WORKING ON OUR FIRST 1

5749
03:31:24,256 --> 03:31:26,591
THAT RUNS, OUR PORTALS THAT RUN

5750
03:31:26,591 --> 03:31:28,894
AGAINST DATABASES NOW CAN SUBMIT

5751
03:31:28,894 --> 03:31:30,962
THE SAME INQUIRIES TO THE SAME

5752
03:31:30,962 --> 03:31:32,163
STRUCTURE AS AN AI AGENT WOULD

5753
03:31:32,163 --> 03:31:33,899
OR AS A USER WORKING THROUGH THE

5754
03:31:33,899 --> 03:31:37,202
DAILY BASIS THEA THROUGH JUPITER

5755
03:31:37,202 --> 03:31:38,236
NOTEBOOK, SO EVERYTHING IS

5756
03:31:38,236 --> 03:31:39,671
COMING THROUGH THE SAME CHANNELS

5757
03:31:39,671 --> 03:31:46,978
WHICH MEANS THAT WE HAVE

5758
03:31:46,978 --> 03:31:48,413
COLLABBATED AND CONSOLIDATED TO

5759
03:31:48,413 --> 03:31:49,080
THE ENTRY DATA.

5760
03:31:49,080 --> 03:31:49,981
SO EVERYONE CAN HAVE ACCESS TO

5761
03:31:49,981 --> 03:31:55,420
THE DAILY BASIS THEA  -- DATA IN

5762
03:31:55,420 --> 03:31:57,155
THE SAME PLACE EVEN IF IT'S NOT

5763
03:31:57,155 --> 03:31:58,256
CO LOCATED OVER TIME.

5764
03:31:58,256 --> 03:32:00,559
SOPHISTICATEDY WE'RE HOPING OVER

5765
03:32:00,559 --> 03:32:02,494
TIME, EVERYBODY GENERATING DATA

5766
03:32:02,494 --> 03:32:04,563
AND PROVIDING NEW MODELS IS

5767
03:32:04,563 --> 03:32:05,297
INTEGRATING INTO THE SAME

5768
03:32:05,297 --> 03:32:08,567
STRUCTURE AND THAT MEANS WE CAN

5769
03:32:08,567 --> 03:32:09,501
FOCUS OUR EFFORTS COLLECTIVE

5770
03:32:09,501 --> 03:32:11,636
LOAMACYY TO MAKE SURE THE

5771
03:32:11,636 --> 03:32:13,338
INFRASTRUCTURE IS ROLELY ROBUST

5772
03:32:13,338 --> 03:32:21,379
BUT IT MEETS DIVERSE USE CASES

5773
03:32:21,379 --> 03:32:23,114
AND APIs FOR USE WITH HUMANS

5774
03:32:23,114 --> 03:32:27,886
BUT THEN WE HAVE ALSO HAVE

5775
03:32:27,886 --> 03:32:31,590
TRAINING EXERCISES BECAUSE THE

5776
03:32:31,590 --> 03:32:32,891
DEPARTMENT OF ENERGY CAN SHUNT

5777
03:32:32,891 --> 03:32:34,526
THAT DATA, AND WE CAN THEN BRING

5778
03:32:34,526 --> 03:32:36,595
THE MODEL BACK INTO THE

5779
03:32:36,595 --> 03:32:37,562
INFRASTRUCTURE FOR OTHERS TO

5780
03:32:37,562 --> 03:32:37,796
USE.

5781
03:32:37,796 --> 03:32:39,230
SO THERE'S A LOT GOING ON IN THE

5782
03:32:39,230 --> 03:32:42,601
BOXES BUT THE GOAL IS TO SHOW

5783
03:32:42,601 --> 03:32:45,837
HOW THE DATA SITS ON THE BOTTOM,

5784
03:32:45,837 --> 03:32:47,772
THE WAYS THAT DATA IS

5785
03:32:47,772 --> 03:32:50,642
REPRESENTED AND THOUGHT ABOUT AN

5786
03:32:50,642 --> 03:32:52,177
ACCESS, SITS ABOVE IT WITH A

5787
03:32:52,177 --> 03:32:53,812
VARIETY OF DIFFERENT SCHEMAS,

5788
03:32:53,812 --> 03:32:55,981
YOU MAINTAIN A CROSS RESOURCE

5789
03:32:55,981 --> 03:32:58,183
DATA MODEL CATALOG AND YOU HAVE

5790
03:32:58,183 --> 03:32:59,351
THIS QUERY INFRASTRUCTURE THAT

5791
03:32:59,351 --> 03:33:01,186
ACTUALLY SUPPORTS ALL OF THE

5792
03:33:01,186 --> 03:33:01,553
USER INTERFACES.

5793
03:33:01,553 --> 03:33:02,754
AND THE WAY I LIKE TO THINK

5794
03:33:02,754 --> 03:33:04,055
ABOUT THIS RIGHT NOW, MAYBE THIS

5795
03:33:04,055 --> 03:33:06,491
IS A GOOD MENTAL MODEL FOR

5796
03:33:06,491 --> 03:33:07,292
EVERYONE HERE, BUT WHAT WE'RE

5797
03:33:07,292 --> 03:33:09,427
TRYING TO DO IS BUILD A LIBRARY,

5798
03:33:09,427 --> 03:33:11,696
SO RIGHT NOW, ALL OF OUR BOOKS

5799
03:33:11,696 --> 03:33:14,833
ARE BASICALLY IN PILES ON A

5800
03:33:14,833 --> 03:33:18,503
FLOOR OR MAYBE LOCKED IN

5801
03:33:18,503 --> 03:33:19,904
SOMEONE'S CLOSET OR DESK DRAWER

5802
03:33:19,904 --> 03:33:21,539
AND WHEN YOU LOOK AT IT SOME OF

5803
03:33:21,539 --> 03:33:23,808
THE PAGES ARE BLANK OR THEY'RE

5804
03:33:23,808 --> 03:33:25,210
MISSING TITLES OR A BUNCH OF

5805
03:33:25,210 --> 03:33:27,178
INFORMATION IS GONE, BUT WHAT A

5806
03:33:27,178 --> 03:33:28,680
PERSON WOULD HAVE TO DO IN ORDER

5807
03:33:28,680 --> 03:33:30,115
TO USE THOSE BOOKS WILL BE TO

5808
03:33:30,115 --> 03:33:32,550
SIT DOWN AND BASICALLY READ THEM

5809
03:33:32,550 --> 03:33:33,852
ALL, TO FIGURE OUT WHAT'S IN

5810
03:33:33,852 --> 03:33:35,687
THEM AND FIGURE OUT IF IT'S

5811
03:33:35,687 --> 03:33:37,055
SOMETHING USEFUL.

5812
03:33:37,055 --> 03:33:39,024
SO THIS CROSS RESOURCE DATA

5813
03:33:39,024 --> 03:33:40,225
CATALOG, YOU CAN THINK OF IT

5814
03:33:40,225 --> 03:33:43,094
LIKE WE'RE BUILDING THE DEWY

5815
03:33:43,094 --> 03:33:46,097
DECIMAL SYSTEM THAT CAN

5816
03:33:46,097 --> 03:33:46,731
REPRESENT DIVERSE ENVIRONMENTS.

5817
03:33:46,731 --> 03:33:47,966
AND ONCE WE HAVE THAT IN PLACE,

5818
03:33:47,966 --> 03:33:49,601
THEN WE CAN ESTABLISH THE

5819
03:33:49,601 --> 03:33:52,070
SHELVING, WE CAN ESTABLISH ORDER

5820
03:33:52,070 --> 03:33:54,839
TO THE LIBRARY AND WE CAN TAKE

5821
03:33:54,839 --> 03:33:58,743
THE BOOKS AND WE CAN ASSIGN THEM

5822
03:33:58,743 --> 03:34:00,011
THE RIGHT CHARACTERISTICS IN THE

5823
03:34:00,011 --> 03:34:01,279
RIGHT MODEL AND SHELVE THEM IN

5824
03:34:01,279 --> 03:34:02,347
THE RIGHT PLACE SO PEOPLE CAN

5825
03:34:02,347 --> 03:34:03,682
ACTUALLY COME TO THE LIBRARY AND

5826
03:34:03,682 --> 03:34:04,849
FIND WHAT THEY'RE LOOKING FOR.

5827
03:34:04,849 --> 03:34:07,285
SO IF THEY'RE INTERESTED IN

5828
03:34:07,285 --> 03:34:10,855
SOMETHING RELATED TO

5829
03:34:10,855 --> 03:34:12,190
METAGENOMICS THEY MIGHT WIND UP

5830
03:34:12,190 --> 03:34:14,659
ON THE JGI SHELVES BUT THEY WILL

5831
03:34:14,659 --> 03:34:17,562
GET THERE 32 THE SHARED CATALOG.

5832
03:34:17,562 --> 03:34:19,130
IT WORKS WELL IN MY BRAIN

5833
03:34:19,130 --> 03:34:21,199
BECAUSE IT ALSO EMPHASIZES THE

5834
03:34:21,199 --> 03:34:22,901
FACT THAT SOME OF THE DATA AND

5835
03:34:22,901 --> 03:34:24,302
INFORMATION MIGHT BE MISSING AND

5836
03:34:24,302 --> 03:34:26,037
SO RIGHT NOW, PEOPLE NEED TO SIT

5837
03:34:26,037 --> 03:34:29,974
DOWN AND FIGURE OUT THE RYE WAYS

5838
03:34:29,974 --> 03:34:32,711
TO PUT THINGS TOGETHER AND OVER

5839
03:34:32,711 --> 03:34:36,781
TIME IF WE ACTUALLY DO ALIGN ON

5840
03:34:36,781 --> 03:34:39,517
THIS SHARED CATALOG, IF WE DO

5841
03:34:39,517 --> 03:34:42,821
ALIGN ON A CANONICLE MODEL, AND

5842
03:34:42,821 --> 03:34:45,790
WE HAVE ENOUGH PEOPLE DOING THE

5843
03:34:45,790 --> 03:34:47,692
SASMYING AND INFORMATION THEN

5844
03:34:47,692 --> 03:34:48,626
THAT'S SOMETHING THAT AI COULD

5845
03:34:48,626 --> 03:34:54,899
HELP US WITH OVER TIME, WHICH IS

5846
03:34:54,899 --> 03:34:55,500
EXCITING.

5847
03:34:55,500 --> 03:34:58,436
SO IN SUMMARY TO WHAT WAS SAID

5848
03:34:58,436 --> 03:35:00,405
BEFORE, THE TEAM SCIENCE IS

5849
03:35:00,405 --> 03:35:00,672
IMPORTANT.

5850
03:35:00,672 --> 03:35:02,140
WE CAN'T OVERLOOK THAT.

5851
03:35:02,140 --> 03:35:04,109
NO 1 CAN CONQUER MOST OF THESE

5852
03:35:04,109 --> 03:35:06,878
SCIENTIFIC CHALLENGES WE HAVE

5853
03:35:06,878 --> 03:35:07,112
ALONE.

5854
03:35:07,112 --> 03:35:09,114
AND YOU CAN GET TO AN 80 MRS

5855
03:35:09,114 --> 03:35:10,815
SOLUTION WITH AI OR WITH YOUR

5856
03:35:10,815 --> 03:35:12,817
CURRENT WORK, AND IT'S FINE BUT

5857
03:35:12,817 --> 03:35:18,022
THAT FINAL 20%, THE HARDEST 20%

5858
03:35:18,022 --> 03:35:19,023
PUTTING THINGS INTO CONTEXT,

5859
03:35:19,023 --> 03:35:21,493
DOING THAT,A LONE IS FEELING

5860
03:35:21,493 --> 03:35:22,560
REALLY IMPOSSIBLE, BECAUSE IT'S

5861
03:35:22,560 --> 03:35:23,828
TOO MUCH WORK, TOO MUCH

5862
03:35:23,828 --> 03:35:25,697
FIDUCIARY FOR ANY SINGLE HUMAN

5863
03:35:25,697 --> 03:35:27,298
OR ANY SINGLE TEAM.

5864
03:35:27,298 --> 03:35:29,033
SO IF WE WORK TOGETHER, THEN WE

5865
03:35:29,033 --> 03:35:30,769
WILL BE ABLE TO CREATE THE KIND

5866
03:35:30,769 --> 03:35:33,004
OF CRITICAL MASS IN OUR DATA,

5867
03:35:33,004 --> 03:35:34,139
CHARACTER EYATION THAT'S NEEDED

5868
03:35:34,139 --> 03:35:36,808
SO THAT EAMENTS AND NLMs AND

5869
03:35:36,808 --> 03:35:38,209
OTHER LARGE SCALE DATA SCIENCE

5870
03:35:38,209 --> 03:35:44,115
TOOLS BECOME REALLY USEFUL FOR

5871
03:35:44,115 --> 03:35:46,184
SCIENCE AND I THINK WE REQUIRE

5872
03:35:46,184 --> 03:35:48,052
COLLECTIVE INPUT FOR THAT AND

5873
03:35:48,052 --> 03:35:48,953
COLLECTIVE INFRASTRUCTURE AND IT

5874
03:35:48,953 --> 03:35:54,325
WILL BE A REALLY INTERESTING AND

5875
03:35:54,325 --> 03:35:57,295
EXCITING TIME FOR STUDYING AI

5876
03:35:57,295 --> 03:35:59,697
TOOLS AND I KNOW IT WAS

5877
03:35:59,697 --> 03:36:01,366
INTERESTING AND DIFFERENT BUT

5878
03:36:01,366 --> 03:36:03,001
NOW WE CAN CHAT AS A PANEL.

5879
03:36:03,001 --> 03:36:06,771
>> THANK YOU VERY MUCH.

5880
03:36:06,771 --> 03:36:07,138
>> YEAH.

5881
03:36:07,138 --> 03:36:07,672
>> THAT DEFINITELY WAS

5882
03:36:07,672 --> 03:36:08,706
INTERESTING AND AS YOU WERE

5883
03:36:08,706 --> 03:36:10,074
TALKING ABOUT THE DATA CATALOG,

5884
03:36:10,074 --> 03:36:12,477
IF I NEED TO HAVE THE DISCUSSION

5885
03:36:12,477 --> 03:36:15,713
SESSION IN REVERSE, WE WILL

5886
03:36:15,713 --> 03:36:18,449
START WITH THE DISCUSSION AND

5887
03:36:18,449 --> 03:36:19,951
WORK BACKWARD BA BEING TO

5888
03:36:19,951 --> 03:36:21,786
DR. MOORE, IF I MAY ASK, WHEN

5889
03:36:21,786 --> 03:36:26,257
YOU WERE TALKING ABOUT THESE 5

5890
03:36:26,257 --> 03:36:29,394
DATABASES AND THE CATALOG,

5891
03:36:29,394 --> 03:36:33,064
COMING IN MY MIND, OH WHAT ABOUT

5892
03:36:33,064 --> 03:36:37,936
RAS, AND SINGLE SIGN ON.

5893
03:36:37,936 --> 03:36:42,240
AM I THINKING OFFTRACK HERE?

5894
03:36:42,240 --> 03:36:44,209
>> OH, AS AN
INFRASTRUCTURE

5895
03:36:44,209 --> 03:36:46,010
NERD, 1 OF THE THINGS THAT

5896
03:36:46,010 --> 03:36:47,979
DRIVES ME CRAZY IS THE THING WE

5897
03:36:47,979 --> 03:36:49,747
DON'T HAVE SINGLE SIGN-ON ACROSS

5898
03:36:49,747 --> 03:36:51,583
ALL THESE SYSTEMS AND 1 THING I

5899
03:36:51,583 --> 03:36:57,789
DIDN'T CALL OUT IN THE

5900
03:36:57,789 --> 03:37:00,525
DISCUSSION IS YOU NEED A SET OF

5901
03:37:00,525 --> 03:37:01,693
LIBRARIANS NOT ONLY DECIDING

5902
03:37:01,693 --> 03:37:03,261
WHAT BOOKS COME INTO THE LIBRARY

5903
03:37:03,261 --> 03:37:05,563
AND HOW THEY'RE CURATED BUT ALSO

5904
03:37:05,563 --> 03:37:09,067
WHO HAS ACCESS AND WHAT ACCESS

5905
03:37:09,067 --> 03:37:10,702
LOOKS LIKE AND WHAT, YOU KNOW

5906
03:37:10,702 --> 03:37:11,903
AND MAYBE BECAUSE LIBRARIES ARE

5907
03:37:11,903 --> 03:37:13,404
SUCH A HAPPY PLACE WHEN I WAS A

5908
03:37:13,404 --> 03:37:15,273
KID BUT I LIKE THIS ANALOGY FOR

5909
03:37:15,273 --> 03:37:16,808
THINKING ABOUT OUR DAT BECAUSE

5910
03:37:16,808 --> 03:37:18,409
YOU GO THERE AND YOU COULD HANG

5911
03:37:18,409 --> 03:37:19,844
OUT WITH THE BOOKS AS MUCH AS

5912
03:37:19,844 --> 03:37:21,179
YOU WANTED BUT IF YOU WANTED TO

5913
03:37:21,179 --> 03:37:22,814
TAKE 1 HOME WITH YOU THERE WAS A

5914
03:37:22,814 --> 03:37:24,949
PROCESS, YOU HAD TO IDENTIFY

5915
03:37:24,949 --> 03:37:25,817
YOURSELF, YOU HAVE TO HAVE A

5916
03:37:25,817 --> 03:37:27,452
CARD AND WE WERE GOING TO KEEP

5917
03:37:27,452 --> 03:37:29,554
TRACK AND IF YOU DIDN'T BRING IT

5918
03:37:29,554 --> 03:37:33,558
BACK ON TIME OR IF YOU MESS IT

5919
03:37:33,558 --> 03:37:36,294
UP, THERE ARE FINES AND THERE'S

5920
03:37:36,294 --> 03:37:38,463
SOME ANALOGUE THERE FOR HOW WE

5921
03:37:38,463 --> 03:37:39,530
THINK ABOUT DATAK ASSESSES

5922
03:37:39,530 --> 03:37:42,166
CONTROLS AND IT STARTS WITH A

5923
03:37:42,166 --> 03:37:43,001
SHARED IDENTITY FOR ANYBODY WHO

5924
03:37:43,001 --> 03:37:44,068
WILL INTEREST THE SYSTEM AND

5925
03:37:44,068 --> 03:37:45,470
TAKE THINGS OUT OF IT AND THEN I

5926
03:37:45,470 --> 03:37:49,207
THINK THERE ARE INTERESTING

5927
03:37:49,207 --> 03:37:51,776
QUESTIONS ABOUT HOW MUCH DATA WE

5928
03:37:51,776 --> 03:37:55,780
LET FLOW THROUGH UNSECURED

5929
03:37:55,780 --> 03:37:56,948
SYSTEMS TOO, AND THEIR FOCUS ON

5930
03:37:56,948 --> 03:37:59,117
THE NUCLEOTIDES CLER SIDE OF THE

5931
03:37:59,117 --> 03:38:00,184
DEPARTMENT OF ENERGY THAT HAVE

5932
03:38:00,184 --> 03:38:01,352
TO THINK ABOUT IT THIS A LOT

5933
03:38:01,352 --> 03:38:03,721
MORE THAN WE DO THE OPEN SIDE.

5934
03:38:03,721 --> 03:38:04,856
BUT WHENEVER YOU'RE TALKING

5935
03:38:04,856 --> 03:38:05,990
ABOUT PATIENT DATA OR HEALTH

5936
03:38:05,990 --> 03:38:07,492
DATA, YOU WANT TO MAKE SMUR

5937
03:38:07,492 --> 03:38:08,660
THAT'S LOCKED DOWN AND YOU WANT

5938
03:38:08,660 --> 03:38:10,061
TO MAKE SURE PEOPLE AREN'T

5939
03:38:10,061 --> 03:38:10,995
ACCESSING IT WHEN THEY SHOULDN'T

5940
03:38:10,995 --> 03:38:14,232
AND NOW WE HAVE ALL SORTS OF

5941
03:38:14,232 --> 03:38:15,967
OTHER COPYRIGHT ISSUES WITH AI

5942
03:38:15,967 --> 03:38:17,335
AND DOING THINGS AT SCALE, BUT

5943
03:38:17,335 --> 03:38:19,737
THE ROOT OF THINKING ABOUT THAT

5944
03:38:19,737 --> 03:38:22,941
IS HAVING THIS LIKE IDENTITY OR

5945
03:38:22,941 --> 03:38:24,275
PASS PORT, RIGHT, SO YOU KNOW

5946
03:38:24,275 --> 03:38:25,677
THE PERSON WHO'S ACCESSING IT IS

5947
03:38:25,677 --> 03:38:27,412
WHO YOU THINK THEY ARE AND THAT

5948
03:38:27,412 --> 03:38:28,680
IS NOT OFF BASE.

5949
03:38:28,680 --> 03:38:30,081
I CAN RAMBLE ABOUT THAT FOR A

5950
03:38:30,081 --> 03:38:31,582
WHILE BECAUSE IT'S A SOURCE OF

5951
03:38:31,582 --> 03:38:32,684
FRUSTRATION THAT EVEN WITHIN THE

5952
03:38:32,684 --> 03:38:35,253
DEPARTMENT OF ENERGY IF I WANT

5953
03:38:35,253 --> 03:38:36,955
TO LOG INTO ECOSYSTEMS RIDGE, IT

5954
03:38:36,955 --> 03:38:39,123
IS A DIFFERENT SET OF

5955
03:38:39,123 --> 03:38:41,292
CREDENTIALS THAN IF I LOG INTO

5956
03:38:41,292 --> 03:38:43,594
BERKELEY LAB, WHY, WHY IN AND

5957
03:38:43,594 --> 03:38:45,163
THEY HAVE REASONS, BUT THEY'RE

5958
03:38:45,163 --> 03:38:45,930
NEVER GOOD 1S.

5959
03:38:45,930 --> 03:38:48,866
BUT IT'S A POLICY PROBLEM.

5960
03:38:48,866 --> 03:38:49,067
OKAY.

5961
03:38:49,067 --> 03:38:53,271
SORRY THAT'S A BIT OF A RANT.

5962
03:38:53,271 --> 03:38:54,472
>> APPRECIATE THAT.

5963
03:38:54,472 --> 03:39:05,016
SO NOW, OPENING UP THIS TALK SO

5964
03:39:06,985 --> 03:39:11,522
DR. FEGNAN CAN TALK TO THE

5965
03:39:11,522 --> 03:39:11,789
AUDIENCE.

5966
03:39:11,789 --> 03:39:12,590
>> LET ME SEE IF THERE ARE

5967
03:39:12,590 --> 03:39:22,967
QUESTIONS IN THE CHAT.

5968
03:39:23,534 --> 03:39:24,469
NOT YET.

5969
03:39:24,469 --> 03:39:29,107
I DON'T DON'T SEE ...

5970
03:39:29,107 --> 03:39:31,542
OKAY, I DON'T SEE HANDS, OH

5971
03:39:31,542 --> 03:39:33,478
THERE'S YES, DR. ANDERSON?

5972
03:39:33,478 --> 03:39:36,381
>> YEAH, THANK YOU ALL FOR

5973
03:39:36,381 --> 03:39:38,116
REALLY IMPRESSIVE WORK, REALEY

5974
03:39:38,116 --> 03:39:42,887
EXCITING TO SEE IT, THE LOVE THE

5975
03:39:42,887 --> 03:39:44,322
ENDOMEET REOSEIS EXAMPLE, IT

5976
03:39:44,322 --> 03:39:45,356
HELPED ME CRYSTALLIZE WHAT WE'RE

5977
03:39:45,356 --> 03:39:46,958
THINKING ABOUT THIS AND HOW WE

5978
03:39:46,958 --> 03:39:49,360
WOULD USE THESE TECHNIQUES, SO

5979
03:39:49,360 --> 03:39:51,996
LET ME SAY I'M A STATISTICIAN BY

5980
03:39:51,996 --> 03:39:53,531
TRAINING BUT REALLY VERY OLD

5981
03:39:53,531 --> 03:39:58,036
SCHOOL, REFLECTING MY AGE, AND

5982
03:39:58,036 --> 03:39:59,904
SO, HOW OFF AND ON, I TALK MODEL

5983
03:39:59,904 --> 03:40:01,205
CITIZEN MY TRAINEES AND OR

5984
03:40:01,205 --> 03:40:05,376
STAFF, I SAY, THE MOST IMPORTANT

5985
03:40:05,376 --> 03:40:07,678
THING IN GETTING AN ANALYSIS

5986
03:40:07,678 --> 03:40:08,980
RIGHT IS GETTING THE RIGHT DATA

5987
03:40:08,980 --> 03:40:11,616
SET OR HAVING THE RIGHT

5988
03:40:11,616 --> 03:40:11,949
DENOMINATOR.

5989
03:40:11,949 --> 03:40:13,017
YOU WILL NOT GET THE RIGHT

5990
03:40:13,017 --> 03:40:14,519
ANSWER IF YOU DON'T START WITH

5991
03:40:14,519 --> 03:40:16,487
THE RIGHT DATA SET SO I'M

5992
03:40:16,487 --> 03:40:17,889
WONDERING IF YOU COULD RIFF ON

5993
03:40:17,889 --> 03:40:24,095
THAT TOPIC ATH BITD WITH REGARD

5994
03:40:24,095 --> 03:40:25,730
TO AI, AND WHAT ARE THE LIMITS

5995
03:40:25,730 --> 03:40:27,565
OF WHERE WE CAN TRUST AI AND

5996
03:40:27,565 --> 03:40:29,534
WHERE WE CAN'T AND FOR THESE

5997
03:40:29,534 --> 03:40:32,170
WHAT SOMEONE CALLED DATA HUNGRY

5998
03:40:32,170 --> 03:40:36,274
ALGORITHMS, HOW ARE WE GOING TO

5999
03:40:36,274 --> 03:40:37,875
REPRODUCE OR REPLICATE THIS WORK

6000
03:40:37,875 --> 03:40:39,143
TO CONVINCE OURSELVES OF THE

6001
03:40:39,143 --> 03:40:44,015
VALIDITY OF THIS WORK?

6002
03:40:44,015 --> 03:40:47,718
>> I'M HAPPY TO JUMP IN
FIRST.

6003
03:40:47,718 --> 03:40:55,827
SO WONDERFUL WONDERFUL QUESTION.

6004
03:40:55,827 --> 03:40:58,930
I JUST WROTE AN EDITORIAL ABOUT

6005
03:40:58,930 --> 03:41:00,431
TRUST AND AI, AND AT A

6006
03:41:00,431 --> 03:41:01,499
COMMERCIAL, WE HAVE VENDOR WHO

6007
03:41:01,499 --> 03:41:04,001
IS WANT TO COME SELL US THEIR

6008
03:41:04,001 --> 03:41:05,436
LATEST AND GREATEST PRODUCTS OF

6009
03:41:05,436 --> 03:41:07,605
AI, AND 1 OF MY ROLE SYSTEM TO

6010
03:41:07,605 --> 03:41:09,607
ASK THE TOUGH QUESTIONS AS AN

6011
03:41:09,607 --> 03:41:11,008
ACADEMIC AND RESEARCHERS AND IN

6012
03:41:11,008 --> 03:41:12,743
FACT, WE HAD 1 COMPANY TELL US

6013
03:41:12,743 --> 03:41:14,912
WE ASK HARDER QUESTIONS THAN ANY

6014
03:41:14,912 --> 03:41:16,781
OTHER INSTITUTION THAT THEY TRY

6015
03:41:16,781 --> 03:41:18,983
TO SELL TOO WHICH WE WEAR AS A

6016
03:41:18,983 --> 03:41:19,484
BADGE OF HONOR.

6017
03:41:19,484 --> 03:41:21,352
BUT 1 OF THE PROBLEMS WITH

6018
03:41:21,352 --> 03:41:23,154
COMMERCIAL COMPANIES THEY DON'T

6019
03:41:23,154 --> 03:41:24,422
SHOW YOU THEIR SOURCE CODE, THEY

6020
03:41:24,422 --> 03:41:25,756
DON'T SHOW WHAT YOU'S GOING ON

6021
03:41:25,756 --> 03:41:27,925
UNDER THE HOOD AND THAT'S A

6022
03:41:27,925 --> 03:41:29,093
BEING PROBLEM IF ARE A HOSPITAL

6023
03:41:29,093 --> 03:41:30,595
OR HEALTH SYSTEM WANTING TO

6024
03:41:30,595 --> 03:41:32,230
ADOPT AI BECAUSE HOW CAN YOU AS

6025
03:41:32,230 --> 03:41:34,532
A CLINICIAN TRUST WHAT THE AI'S

6026
03:41:34,532 --> 03:41:37,034
DOING, HOW CAN I AS A AN I

6027
03:41:37,034 --> 03:41:39,437
RESEARCHER KNOW IT'S USING

6028
03:41:39,437 --> 03:41:40,071
STATE-OF-THE-ART TECHNOLOGY AND

6029
03:41:40,071 --> 03:41:41,072
YOU KNOW WHEN YOU'RE A CLINICIAN

6030
03:41:41,072 --> 03:41:43,274
AND HAVE YOU A PROBLEM PATIENT

6031
03:41:43,274 --> 03:41:45,776
AND YOU HAVE A QUESTION ABOUT

6032
03:41:45,776 --> 03:41:47,578
THE BEST TREATMENT OPTION, CAN

6033
03:41:47,578 --> 03:41:49,981
YOU WALK DOWN THE HALL AND ASK

6034
03:41:49,981 --> 03:41:51,949
YOUR TRUSTED COLLEAGUE AND HAVE

6035
03:41:51,949 --> 03:41:54,585
YOU A TRUST RELATIONSHIP.

6036
03:41:54,585 --> 03:41:56,287
YOU KNOW THEIR TRAINING AND

6037
03:41:56,287 --> 03:41:57,788
TRUST THEIR DECISIONS AND THAT'S

6038
03:41:57,788 --> 03:41:59,323
WHY YOU GO ASK THEM, YOU CAN'T

6039
03:41:59,323 --> 03:42:00,625
DO THAT OF AN AI BECAUSE YOU CAN

6040
03:42:00,625 --> 03:42:01,859
BE THE SEE WHAT IT'S DOING AND I

6041
03:42:01,859 --> 03:42:05,963
THINK THIS IS A BIG PROBLEM.

6042
03:42:05,963 --> 03:42:07,798
I WILL LET THE OTHERS WEIGH IN

6043
03:42:07,798 --> 03:42:09,867
BUT I THINK THAT'S SOMETHING WE

6044
03:42:09,867 --> 03:42:12,003
NEED TO THINK ABOUT.

6045
03:42:12,003 --> 03:42:13,871
>> AGAIN, I CAN ADD TO
WHAT

6046
03:42:13,871 --> 03:42:17,408
JASON IS SAYING, I AGREE WITH

6047
03:42:17,408 --> 03:42:19,310
EVERYTHING HE IS SAID, I THINK

6048
03:42:19,310 --> 03:42:22,947
OF 3 ASPECTS, THE FIRST 1 IS

6049
03:42:22,947 --> 03:42:24,882
GOVERNANCE AND I'M EXPANDING A

6050
03:42:24,882 --> 03:42:26,184
BIT YOUR QUESTION DR. ANDERSON

6051
03:42:26,184 --> 03:42:28,920
BUT IN THE ABSENCE OF

6052
03:42:28,920 --> 03:42:30,855
REGULATION, ABOUT AI, WE STILL

6053
03:42:30,855 --> 03:42:33,391
NEED GOVERNANCE, AND SO, THERE

6054
03:42:33,391 --> 03:42:37,228
ARE BEST PRACTICES ABOUT IT, BUT

6055
03:42:37,228 --> 03:42:39,430
I THINK, I'M TAKING THE LENS OF

6056
03:42:39,430 --> 03:42:40,898
WOMEN'S HELT FOR A SECOND, I

6057
03:42:40,898 --> 03:42:42,567
THINK WE JUST WANT TO MAKE SURE

6058
03:42:42,567 --> 03:42:44,535
WE'RE NOT FORGETTING THE WOMEN

6059
03:42:44,535 --> 03:42:47,305
THEMSELVES AND POTENTIAL AS

6060
03:42:47,305 --> 03:42:48,706
INDIVIDUALS AND PATIENTS AND

6061
03:42:48,706 --> 03:42:50,975
HAVE THEM UNDERSTAND THE

6062
03:42:50,975 --> 03:42:53,611
GOVERNANCE SIMILARLY, WE WANT TO

6063
03:42:53,611 --> 03:42:54,812
MAKE SURE THERE IS EDUCATION

6064
03:42:54,812 --> 03:43:00,418
ABOUT WHAT IT MEANS TO BE

6065
03:43:00,418 --> 03:43:02,987
RELIABLE AND TRUSTWORTHY FOR

6066
03:43:02,987 --> 03:43:05,022
PRACTITIONERS, SO CLINICIANS,

6067
03:43:05,022 --> 03:43:06,857
WHO'S GOING TO BE THE MIXTURES

6068
03:43:06,857 --> 03:43:09,293
THAT THE DOCTORS ARE OF TOMORROW

6069
03:43:09,293 --> 03:43:10,795
ARE EDUCATED CONSUMERS OF AI,

6070
03:43:10,795 --> 03:43:12,430
THAT DOES NOT MEAN KNOW HOW TO

6071
03:43:12,430 --> 03:43:13,864
CREATE AN AI AND PROGRAM IT,

6072
03:43:13,864 --> 03:43:15,399
THAT MEANS KNOW WHAT TO DO WITH

6073
03:43:15,399 --> 03:43:19,503
THE RESULTS OF AN AI TOOL AND

6074
03:43:19,503 --> 03:43:21,205
HOW TO INTERPERATE, KNOW WHAT

6075
03:43:21,205 --> 03:43:23,441
REQUESTYS TO ASK TO PROBE IT AND

6076
03:43:23,441 --> 03:43:24,942
FINALLY ON THE METHOD LOGICAL

6077
03:43:24,942 --> 03:43:26,877
SIDES, YOU KNOW THERE'S

6078
03:43:26,877 --> 03:43:27,945
OBVIOUSLY, IT'S AN ACTIVE FIELD

6079
03:43:27,945 --> 03:43:29,814
OF RESEARCH BUT I THINK WE ARE

6080
03:43:29,814 --> 03:43:32,950
GETTING IN THAT INTERSECTION OF

6081
03:43:32,950 --> 03:43:36,220
AI AND HEALTH TO GOOD METHODS

6082
03:43:36,220 --> 03:43:37,154
AND BEST PRACTICES ABOUT WHAT

6083
03:43:37,154 --> 03:43:40,224
DOES IT MEAN FOR A MODEL TO BE

6084
03:43:40,224 --> 03:43:41,292
ROBUST EMPLOY SO WE'RE THINKING

6085
03:43:41,292 --> 03:43:44,629
IN TERMS OF TIME AS PRACTICES

6086
03:43:44,629 --> 03:43:46,364
EVOLVE, HOW WELL DOES IT DO OR

6087
03:43:46,364 --> 03:43:50,835
THINKING IN TERMS OF GEOGRAPHIC

6088
03:43:50,835 --> 03:43:52,470
SCALES AS DIFFERENT POPULATION

6089
03:43:52,470 --> 03:43:53,437
OR DIFFERENT SITES, ET CETERA,

6090
03:43:53,437 --> 03:43:55,940
ET CETERA BUT YOU KNOW A FEW

6091
03:43:55,940 --> 03:43:57,341
YEARS AGO, EVERYONE WAS

6092
03:43:57,341 --> 03:43:58,509
THINKING, YEAH, WE NEED TO THINK

6093
03:43:58,509 --> 03:44:01,946
ABOUT WHAT IT MEANS TO BE

6094
03:44:01,946 --> 03:44:03,781
ROBUST, AND WE DIDN'T REALLY

6095
03:44:03,781 --> 03:44:05,616
KNOW HOW TO DECOMPOSE THAT INTO

6096
03:44:05,616 --> 03:44:07,051
SPECIFIC EXPERIMENTS AND HOW TO

6097
03:44:07,051 --> 03:44:08,419
OPERATIONALIZE IT AND I THINK

6098
03:44:08,419 --> 03:44:11,722
IT'S -- THERE'S A FANTASTIC KIND

6099
03:44:11,722 --> 03:44:12,690
OF COMMUNITY TO OPERATIONALIZE

6100
03:44:12,690 --> 03:44:14,759
IT IN THE HOUSE DOMAIN, SO THAT

6101
03:44:14,759 --> 03:44:17,728
WE CAN GO FURTHER OR TRUST IN

6102
03:44:17,728 --> 03:44:19,630
THOSE SYSTEMS BUT I WOULD SAY,

6103
03:44:19,630 --> 03:44:25,736
THERE'S DEFINITELY A LOT OF WORK

6104
03:44:25,736 --> 03:44:26,470
TO DO STILL.

6105
03:44:26,470 --> 03:44:29,607
>> WELL, IF I CAN FOLLOW
UP, I

6106
03:44:29,607 --> 03:44:31,676
CAN SEE FOR PRODUCTION APPROACH

6107
03:44:31,676 --> 03:44:35,680
THERE'S OFTEN A GOOD WAY TO

6108
03:44:35,680 --> 03:44:36,213
VALIDATE THAT.

6109
03:44:36,213 --> 03:44:38,849
BUT THERE ARE TIMES WHEN REAL

6110
03:44:38,849 --> 03:44:40,918
WORLD DATA CAN LEAD US ASTRAY,

6111
03:44:40,918 --> 03:44:42,787
IT'S THE SAMPLING PROBLEM, OR WE

6112
03:44:42,787 --> 03:44:46,457
DON'T HAVE AN ADEQUATE

6113
03:44:46,457 --> 03:44:48,025
REPRESENTATIVE OR DATA SET THAT

6114
03:44:48,025 --> 03:44:50,728
YOU'RE WORKING FROM, YOU KNOW SO

6115
03:44:50,728 --> 03:44:53,631
THAT PATIENT POPULATION, AT

6116
03:44:53,631 --> 03:44:54,999
CEDARs MIGHT BE DIFFERENT THAN

6117
03:44:54,999 --> 03:44:57,001
THE PATIENT POPULATION AT

6118
03:44:57,001 --> 03:44:57,468
CHICAGO RUSH.

6119
03:44:57,468 --> 03:45:00,938
AND YOU KNOW IS THIS ALGORITHM

6120
03:45:00,938 --> 03:45:03,741
GOING TO MOVE FROM 1 TO OTHER IN

6121
03:45:03,741 --> 03:45:07,945
A RELIABLE WAY.

6122
03:45:07,945 --> 03:45:10,114
SO, I'M JUST WONDERING HOW WE

6123
03:45:10,114 --> 03:45:11,382
DEAL WITH THAT PARTICULAR

6124
03:45:11,382 --> 03:45:11,849
PROBLEM.

6125
03:45:11,849 --> 03:45:14,852
>> IF I MAY, I WILL GIVE
YOU AN

6126
03:45:14,852 --> 03:45:16,120
ELEMENT OF ANSWERS, I THINK ALL

6127
03:45:16,120 --> 03:45:17,988
OF THE WORK IN THIS DATA

6128
03:45:17,988 --> 03:45:19,824
NETWORKS THAT USE A COMMON DATA

6129
03:45:19,824 --> 03:45:23,694
MODEL, THAT'S 1 OF THE INCENTIVE

6130
03:45:23,694 --> 03:45:26,163
USE FOR THIS IS AS WE GO AWAY

6131
03:45:26,163 --> 03:45:27,431
FROM THE DATA HARMONIZATION

6132
03:45:27,431 --> 03:45:29,333
ISSUES, WE CAN THEN, YOU KNOW

6133
03:45:29,333 --> 03:45:32,703
THAT'S TAKEN CARE OF TO SOME

6134
03:45:32,703 --> 03:45:34,605
EXTENT, YOU NOT FULLY BUT TO

6135
03:45:34,605 --> 03:45:37,208
SOME EXTENT, THEN WE CAN GO ASK

6136
03:45:37,208 --> 03:45:40,411
THE REQUESTYS OF TRAIN ON 1

6137
03:45:40,411 --> 03:45:43,147
SITE, TEST ON ANOTHER OR LIKE

6138
03:45:43,147 --> 03:45:45,349
YAISON MENTIONED WHERE YOU DO

6139
03:45:45,349 --> 03:45:46,517
FEDERATED LEARNING WHERE YOU

6140
03:45:46,517 --> 03:45:47,618
EMBRACE THE DIVERSITY OF THE

6141
03:45:47,618 --> 03:45:49,353
SITES AND ASK THE AI TO HANDLE

6142
03:45:49,353 --> 03:45:51,455
IT FOR YOU, BUT I THINK WHAT I

6143
03:45:51,455 --> 03:45:52,957
WOULD SAY IS IMPORTANT IN ALL OF

6144
03:45:52,957 --> 03:45:54,959
THESE METHODS IS TO REALLY FOR

6145
03:45:54,959 --> 03:45:59,897
EACH QUESTION, THERE'S GOING TO

6146
03:45:59,897 --> 03:46:01,031
BE DIFFERENT PROBLEMS, IS IT

6147
03:46:01,031 --> 03:46:03,167
TIME, IS IT SCALE THESE KINDS OF

6148
03:46:03,167 --> 03:46:04,568
THINGS AND SO, REALLY, THINKING

6149
03:46:04,568 --> 03:46:05,636
ABOUT THE QUESTION, WE'RE TRYING

6150
03:46:05,636 --> 03:46:09,340
TO ANSWER IS GOING TO BE

6151
03:46:09,340 --> 03:46:10,908
CRITICAL, RIGHT?

6152
03:46:10,908 --> 03:46:14,712
>> THANK YOU.

6153
03:46:14,712 --> 03:46:15,079
DR. FAGNAN?

6154
03:46:15,079 --> 03:46:21,018
NYEAH, I JUST COMPLETELY AGREE

6155
03:46:21,018 --> 03:46:25,723
ABOUT THE TRUST ISSUES.

6156
03:46:25,723 --> 03:46:26,624
I AM WORRIED.

6157
03:46:26,624 --> 03:46:28,159
A LONG TIME AGO, I GAVE A TALK

6158
03:46:28,159 --> 03:46:32,863
AT A MEETING SHOWING A

6159
03:46:32,863 --> 03:46:34,498
SIMULATION OF HIGH INTENSITY

6160
03:46:34,498 --> 03:46:35,399
FOCUSED ULTRASOUND TREATMENT DID

6161
03:46:35,399 --> 03:46:38,068
IT WAS A SIMULATION AND 2

6162
03:46:38,068 --> 03:46:39,603
DIMENSIONAL, NOT AT ALL

6163
03:46:39,603 --> 03:46:40,304
REPRESENTATIVE OF REALITY BUT

6164
03:46:40,304 --> 03:46:41,739
MOST FOLKS IN THE AUDIENCE

6165
03:46:41,739 --> 03:46:44,442
WANTED TO BELIEVE THAT IT WAS

6166
03:46:44,442 --> 03:46:45,476
REPRESENTATIVE OF WHAT A

6167
03:46:45,476 --> 03:46:48,646
TREATMENT MIGHT LOOK LIKE FOR A

6168
03:46:48,646 --> 03:46:49,113
PATIENT.

6169
03:46:49,113 --> 03:46:51,282
WE HAVE A DESIRE AS HUMANS TO

6170
03:46:51,282 --> 03:46:53,884
WANT TO PUT A LOT OF FAITH IN

6171
03:46:53,884 --> 03:46:55,419
THE COMPUTER AND LIKE, THINK

6172
03:46:55,419 --> 03:46:56,921
THAT IT'S SMARTER THAN US.

6173
03:46:56,921 --> 03:47:00,090
WE HAVE TO REMEMBER THAT IT'S

6174
03:47:00,090 --> 03:47:04,261
BUILT BY US ISSUES @ MOMENT.

6175
03:47:04,261 --> 03:47:05,529
LIKE THE EMERGENT INTELLIGENT

6176
03:47:05,529 --> 03:47:06,597
PROPERTIES THAT WE'RE OBSERVING

6177
03:47:06,597 --> 03:47:08,332
AND MAYBE THIS WAS ALREADY

6178
03:47:08,332 --> 03:47:13,370
DISCUSSED ARE THINGS THAT ARE

6179
03:47:13,370 --> 03:47:15,105
THERE'S THE CONCEPT OF THE

6180
03:47:15,105 --> 03:47:16,106
EYEBALL NORM IN MATHEMATICS

6181
03:47:16,106 --> 03:47:17,575
WHERE YOU LOOK AT A SIMULATION

6182
03:47:17,575 --> 03:47:19,343
AND A PICTURE AND THAT'S PRETTY

6183
03:47:19,343 --> 03:47:19,677
GOOD.

6184
03:47:19,677 --> 03:47:21,679
AND THEN YOU ACTUALLY LOOK AT

6185
03:47:21,679 --> 03:47:22,947
THE FUNDAMENTAL PRINCIPLES OF

6186
03:47:22,947 --> 03:47:24,448
LIKE WHAT EQUATIONS AM I SOLVING

6187
03:47:24,448 --> 03:47:25,983
AND DID THE COMPUTER DO THIS

6188
03:47:25,983 --> 03:47:29,086
ACCURATELY AND YOU SEE IT'S JUST

6189
03:47:29,086 --> 03:47:31,188
RIFE WITH ERROR AND RIGHT NOW WE

6190
03:47:31,188 --> 03:47:32,857
HAVE THINGS WITH LLMs THAT

6191
03:47:32,857 --> 03:47:34,592
WEEM ARE REALLY EXCITED ABOUT

6192
03:47:34,592 --> 03:47:36,660
BECAUSE THERE'S LIKE A LOT OF

6193
03:47:36,660 --> 03:47:38,028
EYEBALL NORM LOOKS GOOD ENOUGH

6194
03:47:38,028 --> 03:47:39,763
AND I WOULD ARGUE FOR SCIENCE

6195
03:47:39,763 --> 03:47:43,100
THAT IS NOT THE BAR WE SHOULD BE

6196
03:47:43,100 --> 03:47:44,368
USING HOWEVER, I WORRY IT MIGHT

6197
03:47:44,368 --> 03:47:48,005
BE THE BAR FOR GETTING A

6198
03:47:48,005 --> 03:47:48,672
PUBLICATION OUT, RIGHT?

6199
03:47:48,672 --> 03:47:50,341
AND IT MIGHT BE A BAR FOR SORT

6200
03:47:50,341 --> 03:47:52,276
OF PLAYING TO THE INCENTIVE

6201
03:47:52,276 --> 03:47:54,345
STRUCTURE THAT WE HAVE.

6202
03:47:54,345 --> 03:47:56,180
AND SO BALANCING THIS SORT OF

6203
03:47:56,180 --> 03:47:57,915
REAL CONCERNS AGAINST FOLKS WHO

6204
03:47:57,915 --> 03:47:59,550
ARE GOING TO PUT OUT

6205
03:47:59,550 --> 03:48:01,819
PUBLICATIONS BECAUSE THEY NEED

6206
03:48:01,819 --> 03:48:05,189
TO, IS REALLY GOING TO BE A

6207
03:48:05,189 --> 03:48:06,757
CHALLENGE AND OUR FUNDERS WHO

6208
03:48:06,757 --> 03:48:08,592
ARE LOOKING FOR ANSWERS TO SOME

6209
03:48:08,592 --> 03:48:11,362
OF THESE REALLY EXPENSIVE

6210
03:48:11,362 --> 03:48:13,464
PROBLEMS, DATA HARMONIZATION IS

6211
03:48:13,464 --> 03:48:14,732
EXPENSIVE, IT GETS MORE

6212
03:48:14,732 --> 03:48:17,234
EXPENSIVE THE MORE LIKE,

6213
03:48:17,234 --> 03:48:18,402
EXPERIMENTS YOU DO, RIGHT?

6214
03:48:18,402 --> 03:48:20,638
AND THE MORE DATA YOU GENERATE

6215
03:48:20,638 --> 03:48:22,006
AND THERE'S NOT NECESSARILY AN

6216
03:48:22,006 --> 03:48:23,507
INTEREST IN FUNDING IT, LIKE

6217
03:48:23,507 --> 03:48:25,709
IT'S CHALLENGING TO MAINTAIN

6218
03:48:25,709 --> 03:48:26,410
FUNDING FOR NATIONAL

6219
03:48:26,410 --> 03:48:27,811
REPOSITORIES AND SO THERE IS

6220
03:48:27,811 --> 03:48:30,548
SOMETHING HERE WHERE LIKE, I

6221
03:48:30,548 --> 03:48:32,416
WORRY ABOUT HOW IT GETS

6222
03:48:32,416 --> 03:48:33,517
ADVERTISED AND I WORRY ABOUT THE

6223
03:48:33,517 --> 03:48:35,419
HYPE AND I WORRY ABOUT GOING

6224
03:48:35,419 --> 03:48:37,721
DOWN THESE RABBIT HOLES WHERE

6225
03:48:37,721 --> 03:48:38,689
PEOPLE AREN'T JUST WILLING TO

6226
03:48:38,689 --> 03:48:40,558
STAND UP AND SAY THEY HAVE TRUST

6227
03:48:40,558 --> 03:48:41,926
ISSUES, TOO AND I THINK YOU HAVE

6228
03:48:41,926 --> 03:48:47,231
TO FALL BACK ON LIKE

6229
03:48:47,231 --> 03:48:48,098
FOUNDATIONAL STATISTICS TO

6230
03:48:48,098 --> 03:48:48,899
REALLY UNDERSTAND THE DATA

6231
03:48:48,899 --> 03:48:50,734
ITSELF AND UNDERSTAND IF YOU

6232
03:48:50,734 --> 03:48:53,971
WERE DESIGNING AN EXPERIMENT

6233
03:48:53,971 --> 03:48:54,672
CORRECTLY AND BE REALLY

6234
03:48:54,672 --> 03:48:57,575
JUDICIOUS ABOUT THE TOOLS YOU

6235
03:48:57,575 --> 03:49:00,678
USE BUT FOR ANYTHING YOU WANT

6236
03:49:00,678 --> 03:49:01,879
ACCURACY AVOID LLMs, FOR NOW,

6237
03:49:01,879 --> 03:49:06,884
THAT'S JUST NOT WHAT THEY'RE

6238
03:49:06,884 --> 03:49:07,885
BUILT TO DO.

6239
03:49:07,885 --> 03:49:10,821
>> DR. MOORE, A QUESTION,
YOU

6240
03:49:10,821 --> 03:49:12,456
REALLY KINDLY POINTED OUT ALL

6241
03:49:12,456 --> 03:49:13,824
THE CHALLENGES OF DATA AND WE

6242
03:49:13,824 --> 03:49:15,826
LIVE SOME OF THOSE ON A DAILY

6243
03:49:15,826 --> 03:49:17,561
BASIS, THEY'RE HARD TO WORK

6244
03:49:17,561 --> 03:49:21,098
WITH, THEY'RE NOT STANDARDIZED,

6245
03:49:21,098 --> 03:49:22,833
THEY'RE COSTLY, AND THAT'S TRUE

6246
03:49:22,833 --> 03:49:25,169
FOR ALL THE CHALLENGES THAT YOU

6247
03:49:25,169 --> 03:49:27,671
POINT OUT, I WONDER IF YOU WOULD

6248
03:49:27,671 --> 03:49:34,311
POINT OUT A USE CASE WITH AI-LLM

6249
03:49:34,311 --> 03:49:36,580
WHERE THERE'S USE CASE INTERSECT

6250
03:49:36,580 --> 03:49:38,315
WHAT THE LEARNING HEALTH SYSTEM?

6251
03:49:38,315 --> 03:49:40,851
YOU HAVE THE PRIVILEGE OF

6252
03:49:40,851 --> 03:49:42,786
LIVING, HAVING 1 SIDE OF YOUR

6253
03:49:42,786 --> 03:49:44,154
BRAIN WORKING WITH DATA AND THE

6254
03:49:44,154 --> 03:49:45,589
OTHER SIDE OF YOUR BRAIN WORKING

6255
03:49:45,589 --> 03:49:50,060
WITH THE PATIENTS AND THE

6256
03:49:50,060 --> 03:49:53,230
CLINICAL SETTINGS SO YOU WOULD

6257
03:49:53,230 --> 03:49:54,632
IDEAL TO UNDERSTAND WHERE DO

6258
03:49:54,632 --> 03:49:58,836
THEY INTERSECT IN THIS LEARNING

6259
03:49:58,836 --> 03:49:59,269
HEALTH SYSTEM?

6260
03:49:59,269 --> 03:50:02,039
OH IT'S A GREAT QUESTION, 1 OF

6261
03:50:02,039 --> 03:50:03,440
THE GREATLY UNDERAPPRECIATED

6262
03:50:03,440 --> 03:50:05,242
AREAS WHERE AI HAS A ROLE TO

6263
03:50:05,242 --> 03:50:06,910
PLAY AND IN A HEALTH SYSTEM IS

6264
03:50:06,910 --> 03:50:08,078
THE PATIENT EXPERIENCE, WE DON'T

6265
03:50:08,078 --> 03:50:09,647
THINK ENOUGH -- WE ALL

6266
03:50:09,647 --> 03:50:11,482
EXPERIENCE THIS OURSELVES AS

6267
03:50:11,482 --> 03:50:13,884
PATIENTS, YOU KNOW HEALTH

6268
03:50:13,884 --> 03:50:15,052
SYSTEMS ARE CONFUSING, IT'S

6269
03:50:15,052 --> 03:50:16,320
STRESSFUL, IT'S A HARD TIME WHEN

6270
03:50:16,320 --> 03:50:17,721
YOU HAVE A HEALTH ISSUE AND

6271
03:50:17,721 --> 03:50:19,123
GETTING THE TO CARE YOU NEED AND

6272
03:50:19,123 --> 03:50:20,758
GETTING TO THE RIGHT DOCTOR AND

6273
03:50:20,758 --> 03:50:22,493
NAVIGATING THROUGH A HEALTH

6274
03:50:22,493 --> 03:50:23,527
SYSTEM IS CONFUSING FOR ALL OF

6275
03:50:23,527 --> 03:50:24,962
US THAT WORK IN A HEALTH SYSTEM

6276
03:50:24,962 --> 03:50:29,433
AND SO I THINK A LOT ABOUT THE

6277
03:50:29,433 --> 03:50:30,968
PATIENT EXPERIENCE AND WE HAVE

6278
03:50:30,968 --> 03:50:33,604
AN APP A LARGE LANGUAGE MODEL

6279
03:50:33,604 --> 03:50:37,841
BASED APP AT CEDAR SINAI, IT'S

6280
03:50:37,841 --> 03:50:39,510
CALLED CS-CONNECT SO IT'S AN APP

6281
03:50:39,510 --> 03:50:40,878
ANYBODY IN THE STATE OF

6282
03:50:40,878 --> 03:50:41,845
CALIFORNIA CAN DOWNLOAD IN THE

6283
03:50:41,845 --> 03:50:45,582
APP STORE AND YOU CAN START

6284
03:50:45,582 --> 03:50:47,117
ASKING QUESTIONS AND ENTERING

6285
03:50:47,117 --> 03:50:49,053
HEALTH INFORMATION, THE AI WILL

6286
03:50:49,053 --> 03:50:51,488
ASK YOU WEB CONNECTEDS AND GIVE

6287
03:50:51,488 --> 03:50:53,590
YOU A PRELIMINARY DIAGNOSIS, AND

6288
03:50:53,590 --> 03:50:55,426
THERE'S A BUTTON THAT SAYS TALK

6289
03:50:55,426 --> 03:50:56,927
TO A DOCTOR, YOU CAN PUSH THAT

6290
03:50:56,927 --> 03:50:58,696
BUTTON AND TALK TO A DOCTOR

6291
03:50:58,696 --> 03:51:00,731
IMMEDIATELY, A DOCTOR WE EMPLOY

6292
03:51:00,731 --> 03:51:02,933
AND WITHIN MINUTES BE TALKING TO

6293
03:51:02,933 --> 03:51:04,868
A REAL PERSON ABOUT YOUR HEALTH

6294
03:51:04,868 --> 03:51:06,403
SITUATION, THE APP THEN HELPS

6295
03:51:06,403 --> 03:51:07,771
YOU SCHEDULE AN ASHES POINTMENT,

6296
03:51:07,771 --> 03:51:09,306
GET IN TO SEE A DOCTOR AND WHEN

6297
03:51:09,306 --> 03:51:10,874
HAVE YOU GO TO HAVE YOUR FIRST

6298
03:51:10,874 --> 03:51:12,176
ENCOUNTER WITH A PHYSICIAN OR

6299
03:51:12,176 --> 03:51:13,243
CLINICIAN, THE SUMMARY OF WHAT

6300
03:51:13,243 --> 03:51:14,678
THE AI LEARNED ABOUT YOU IS

6301
03:51:14,678 --> 03:51:16,547
ALREADY PROVIDED TO THEM, SO TO

6302
03:51:16,547 --> 03:51:20,150
SAVE TIME, SO THIS, I THINK THIS

6303
03:51:20,150 --> 03:51:21,885
IS AN EXAMPLE WHERE LARGE

6304
03:51:21,885 --> 03:51:23,754
LANGUAGE MODELS AND AI GRITTILY,

6305
03:51:23,754 --> 03:51:24,822
GREATLY IMPROVES THE PATIENT

6306
03:51:24,822 --> 03:51:25,789
EXPERIENCE, GETTING THEM INTO

6307
03:51:25,789 --> 03:51:29,893
THE CLINICS SO THEY CAN BINE AND

6308
03:51:29,893 --> 03:51:33,897
-- CAN BE SEEN AND HAVE THEIR

6309
03:51:33,897 --> 03:51:34,665
CONDITION DEALT WITH.

6310
03:51:34,665 --> 03:51:36,100
IT GIVES THEM A HEAD START ON

6311
03:51:36,100 --> 03:51:37,367
HOW TO INTERACT WITH THE PATIENT

6312
03:51:37,367 --> 03:51:38,902
AND GET THEM THE CARE THEY NEED.

6313
03:51:38,902 --> 03:51:40,170
WE'VE BEEN USING THIS FOR ABOUT

6314
03:51:40,170 --> 03:51:44,475
A YEAR AND A HALF NOW AND WE'VE

6315
03:51:44,475 --> 03:51:46,343
HAD 10S OF THOUSANDS OF PATIENTS

6316
03:51:46,343 --> 03:51:47,511
COME INTO OUR HEALTH SYSTEM THAT

6317
03:51:47,511 --> 03:51:49,580
HAVE NEVER BEEN PATES BEFORE AND

6318
03:51:49,580 --> 03:51:50,447
THE REVIEWS ARE QUITE GOOD.

6319
03:51:50,447 --> 03:51:52,750
SO I THINK THERE IS A ROLE FOR

6320
03:51:52,750 --> 03:51:57,688
LARGE LANGUAGE MODELS IN HEALTH

6321
03:51:57,688 --> 03:51:59,323
SYSTEMS, AND YOU KNOW THEY'RE

6322
03:51:59,323 --> 03:52:00,591
BEING EVALUATED ACROSS THE

6323
03:52:00,591 --> 03:52:01,859
SPECTRUM OF THINGS CAN YOU

6324
03:52:01,859 --> 03:52:03,127
IMAGINE USING LARGE LANGUAGE

6325
03:52:03,127 --> 03:52:03,994
MODELS FOR.

6326
03:52:03,994 --> 03:52:05,162
SOMETIMES THEY'RE USEFUL,

6327
03:52:05,162 --> 03:52:06,764
SOMETIMES THEY'RE NOT BUT I

6328
03:52:06,764 --> 03:52:09,500
THINK THAT'S AN EXAMPLE WHERE IT

6329
03:52:09,500 --> 03:52:12,369
GREATLY IMPROVES THE PATIENT

6330
03:52:12,369 --> 03:52:12,669
EXPERIENCE.

6331
03:52:12,669 --> 03:52:16,206
>> PRETTY IMPRESSIVE DATA
IN

6332
03:52:16,206 --> 03:52:17,908
TERMS OF THE SUCCESS.

6333
03:52:17,908 --> 03:52:21,879
I KNOW WE, I WILL CONFESS WE

6334
03:52:21,879 --> 03:52:26,683
FUNDED SOME HEALTH EDUCATION LLM

6335
03:52:26,683 --> 03:52:30,387
CHAT BOT FOR UNDERSERVED

6336
03:52:30,387 --> 03:52:31,188
COMMUNITIES STOCK EXCHANGE

6337
03:52:31,188 --> 03:52:34,958
REMIND THEM OF THE NEED TO MAKE

6338
03:52:34,958 --> 03:52:37,094
THE MEDICATIONS, AND SAY HYPER

6339
03:52:37,094 --> 03:52:38,962
TENSIVE, WHAT I ALWAYS FELT IS

6340
03:52:38,962 --> 03:52:41,565
MISSING IS IT DIDN'T FOLLOW UP

6341
03:52:41,565 --> 03:52:43,767
WITH, HERE'S TO CONTACT AND MAKE

6342
03:52:43,767 --> 03:52:45,869
AN APPOINTMENT BECAUSE JUST AS A

6343
03:52:45,869 --> 03:52:46,904
REMINDER THEY MAY MAKE MEDICINE

6344
03:52:46,904 --> 03:52:48,972
FOR THAT DAY OR EACH FOR A WEEK

6345
03:52:48,972 --> 03:52:50,808
BUT THEY MAY ACTUALLY SHOULD BE

6346
03:52:50,808 --> 03:52:51,975
SEEN, AND MAKING IT EASY FOR

6347
03:52:51,975 --> 03:52:53,944
THEM TO MAKE AN APPOINTMENT,

6348
03:52:53,944 --> 03:52:58,482
WHICH YOU HAVE IN YOUR APP, IT'S

6349
03:52:58,482 --> 03:52:58,715
AMAZING.

6350
03:52:58,715 --> 03:53:00,184
>> YEAH, IT'S SO EASY TO
DO NOW.

6351
03:53:00,184 --> 03:53:01,351
WE HAVE THE TECHNOLOGY, WE JUST

6352
03:53:01,351 --> 03:53:03,153
HAVE TO PUT IT TO WO, ON BEHALF

6353
03:53:03,153 --> 03:53:04,521
OF PATIENTS TO MAKE IT EASY FOR

6354
03:53:04,521 --> 03:53:08,358
THEM TO GET THE CARE THEY NEED.

6355
03:53:08,358 --> 03:53:10,427
A LOT OF PEOPLE DON'T DO IT

6356
03:53:10,427 --> 03:53:12,796
BECAUSE IT'S SO CONFUSING AND

6357
03:53:12,796 --> 03:53:13,063
DIFFICULT.

6358
03:53:13,063 --> 03:53:13,497
>> RIGHT, RIGHT.

6359
03:53:13,497 --> 03:53:14,064
THANK YOU FOR THAT.

6360
03:53:14,064 --> 03:53:19,069
NOW I HAVE A QUESTION FOR

6361
03:53:19,069 --> 03:53:20,337
DR. ELHADAD, IF OUR AUDIENCE, I

6362
03:53:20,337 --> 03:53:25,342
DON'T SEE HANDS UP, IF I MAY

6363
03:53:25,342 --> 03:53:29,913
ASK, YOU MENTIONED THE USE OF

6364
03:53:29,913 --> 03:53:34,351
MOBILE HEALTH AND AND THE

6365
03:53:34,351 --> 03:53:35,485
ENDOMETRIOSIS PATIENTS TEND TO

6366
03:53:35,485 --> 03:53:37,688
BE A BIT MORE GUARDED ABOUT

6367
03:53:37,688 --> 03:53:41,058
THEIR PRIVACY, THE MOBILE HEALTH

6368
03:53:41,058 --> 03:53:45,195
DEVICE ITSELF A CONCERN IN TERMS

6369
03:53:45,195 --> 03:53:46,363
OF PROTECTING PRIVACY?

6370
03:53:46,363 --> 03:53:47,497
>> NO, THAT'S A GREAT
QUESTION

6371
03:53:47,497 --> 03:53:49,766
AND I THINK THE MOBILE HEALTH IS

6372
03:53:49,766 --> 03:53:52,035
ACTUALLY THE LEAST OF THE

6373
03:53:52,035 --> 03:53:54,471
WORRIES OF THE PATIENTS.

6374
03:53:54,471 --> 03:53:57,407
IT'S REALLY ABOUT IN THE CASE OF

6375
03:53:57,407 --> 03:54:00,244
ENDOMETRIOSIS THERE'S A LOT OF

6376
03:54:00,244 --> 03:54:01,011
REPRODUCTIVE HEALTH INFORMATION

6377
03:54:01,011 --> 03:54:03,580
THAT THEY'RE GIVING TO

6378
03:54:03,580 --> 03:54:07,084
RESEARCHERS AND THEY REALIZE HOW

6379
03:54:07,084 --> 03:54:10,187
SENSITIVE THE DATA IS AND SO

6380
03:54:10,187 --> 03:54:11,688
THEY'RE JUST WORRIED ABOUT WHO

6381
03:54:11,688 --> 03:54:14,291
IS GOING TO ACCESS THE DATA.

6382
03:54:14,291 --> 03:54:16,727
WHETHER IT WOULD BE THE -- THE

6383
03:54:16,727 --> 03:54:18,595
SAME WAY THEY'RE ACTUALLY

6384
03:54:18,595 --> 03:54:20,631
WORRIED FOR ELECTRONIC HEALTH

6385
03:54:20,631 --> 03:54:22,266
RECORD AND ROUTINE CARE.

6386
03:54:22,266 --> 03:54:25,435
THAT'S 1 ASPECT AND THEN THEY'RE

6387
03:54:25,435 --> 03:54:27,004
ALSO WORRY BODY MISUSE OF THE

6388
03:54:27,004 --> 03:54:31,675
DATA MAYBE NOT FOR THEM

6389
03:54:31,675 --> 03:54:33,477
SPECIFICALLY, BUT FOR

6390
03:54:33,477 --> 03:54:34,544
ENDOMETRIOSIS PATIENTS AS A

6391
03:54:34,544 --> 03:54:36,013
COMMUNITY IN A SUBPOPULATION

6392
03:54:36,013 --> 03:54:40,350
WHERE IT'S MORE ABOUT MISTRUST

6393
03:54:40,350 --> 03:54:42,286
OF POTENTIALLY AND I WILL

6394
03:54:42,286 --> 03:54:43,287
SEPARATE MYSELF FROM THE

6395
03:54:43,287 --> 03:54:44,154
ENDOMETRIOSIS COMMUNITY FOR A

6396
03:54:44,154 --> 03:54:46,056
SECOND BUT THAT'S WHAT WE HEAR

6397
03:54:46,056 --> 03:54:49,693
IS A BIG MISTRUST IN

6398
03:54:49,693 --> 03:54:50,427
PHARMACEUTICAL COMPANIES WHERE

6399
03:54:50,427 --> 03:54:52,429
THEY FEEL THEY DON'T HAVE THEIR

6400
03:54:52,429 --> 03:54:53,597
INTEREST IN MIND EMPLOY THEY

6401
03:54:53,597 --> 03:54:55,132
FEEL THEY'RE NOT LOOKING FOR A

6402
03:54:55,132 --> 03:54:56,066
CURE, THEY'RE LOOKING FOR

6403
03:54:56,066 --> 03:54:57,601
MITIGATION THAT IS TREATING

6404
03:54:57,601 --> 03:54:58,568
THEIR SYMPTOMS, YOU KNOW AND I

6405
03:54:58,568 --> 03:54:59,736
THINK WHAT IT TALKS ABOUT IS

6406
03:54:59,736 --> 03:55:02,339
JUST THE FACT THAT IT'S AN

6407
03:55:02,339 --> 03:55:03,840
UNDERSTUDIED DISEASE MORE THAN

6408
03:55:03,840 --> 03:55:05,776
ANYTHING ELSE AND THAT THE WAY

6409
03:55:05,776 --> 03:55:07,878
TO PERCEIVED BY PATIENTS IS NO

6410
03:55:07,878 --> 03:55:10,547
1'S CARRYING FOR US AND NO 1 IS

6411
03:55:10,547 --> 03:55:14,318
PAYING ATTENTION TO OUR NEEDS

6412
03:55:14,318 --> 03:55:16,787
AND SO I THINK THERE THERE'S TBO

6413
03:55:16,787 --> 03:55:18,522
KINDS OF WORRIES ABOUT IF THE

6414
03:55:18,522 --> 03:55:20,190
DATA IS USED BUT FOR THE SAKE OF

6415
03:55:20,190 --> 03:55:21,124
CREATING DRUGS THAT ARE NOT

6416
03:55:21,124 --> 03:55:25,495
GOING TO BE HELPFUL TO

6417
03:55:25,495 --> 03:55:26,196
ENDOMETRIOSIS PATIENTS, THEY'RE

6418
03:55:26,196 --> 03:55:28,065
VERY WORRY BODY THAT AND GUARDED

6419
03:55:28,065 --> 03:55:30,834
ABOUT SHARING THEIR DATA.

6420
03:55:30,834 --> 03:55:35,639
SO, INDIVIDUAL WORRIES, YOU

6421
03:55:35,639 --> 03:55:38,141
KNOW, AS I WNL DO I WANT TO

6422
03:55:38,141 --> 03:55:40,944
SHARE INFORMATION ON MY

6423
03:55:40,944 --> 03:55:42,512
REPRODUCTION HEGHT AND THEN MORE

6424
03:55:42,512 --> 03:55:43,613
THE POPULATION BASED WORRY.

6425
03:55:43,613 --> 03:55:53,056
>> THANK YOU VERY MUCH.

6426
03:55:53,056 --> 03:55:54,558
>> DR. MELENZ, GOING BACK
A BIT,

6427
03:55:54,558 --> 03:55:55,959
SORRY DEPARTMENT GET MY HAND UP

6428
03:55:55,959 --> 03:55:57,594
FAST ENOUGH BUT THIS IS A FOLLOW

6429
03:55:57,594 --> 03:55:59,663
UP ON DR. ANDERSON'S I THINK

6430
03:55:59,663 --> 03:56:03,367
QUESTION AND THIS 1 IS FOR

6431
03:56:03,367 --> 03:56:07,337
DR. MOORE, IT'S MORE SORT OF A

6432
03:56:07,337 --> 03:56:08,238
TERMINOLOGY CLARIFICATION, YOU

6433
03:56:08,238 --> 03:56:10,340
KNOW I'M NOT AN EXPERT IN THE

6434
03:56:10,340 --> 03:56:11,475
FIELD YOU'RE DISCUSSING BUT YOU

6435
03:56:11,475 --> 03:56:13,110
TALKED ABOUT 1 OF THE CHALLENGES

6436
03:56:13,110 --> 03:56:16,546
AS BEING, YOU KNOW YOU WANT AI

6437
03:56:16,546 --> 03:56:20,917
GENERAL, YOU WANT THE SAME FOR

6438
03:56:20,917 --> 03:56:22,719
ALL PEOPLE AND I DIDN'T HEAR YOU

6439
03:56:22,719 --> 03:56:26,723
USE THE TERM LYING ALGORITHMIC

6440
03:56:26,723 --> 03:56:28,558
FAIRNESS, AND WONDERED JUST SORT

6441
03:56:28,558 --> 03:56:30,060
OF FROM AN OPERATIONALLY

6442
03:56:30,060 --> 03:56:32,896
DEFINING SOME OF THESE NEWER

6443
03:56:32,896 --> 03:56:36,199
TERMS, DO YOU USE KIND OF AI

6444
03:56:36,199 --> 03:56:37,801
GENERAL IN ALGORITHMIC FAIRNESS

6445
03:56:37,801 --> 03:56:42,739
AND SIN NONE MOUSILY OR ANY

6446
03:56:42,739 --> 03:56:43,740
THOUGHTS THERE?

6447
03:56:43,740 --> 03:56:45,108
>> YEAH, THAT'S EXACTLY
WHAT I

6448
03:56:45,108 --> 03:56:46,510
MEANT, YOU KNOW IN MACHINE

6449
03:56:46,510 --> 03:56:48,378
LEARNING WE OFTEN TALK ABOUT

6450
03:56:48,378 --> 03:56:50,947
GENERALIZATION, DOES THE MODEL

6451
03:56:50,947 --> 03:56:52,015
GENERALIZE TO ALL PEOPLE SO

6452
03:56:52,015 --> 03:56:53,550
THAT'S WHY I USE THAT WORD BUT

6453
03:56:53,550 --> 03:56:54,718
FAIRNESS IS ANOTHER WORD YOU

6454
03:56:54,718 --> 03:56:57,054
COULD USE MAKING SURE THE MODEL

6455
03:56:57,054 --> 03:57:05,328
IS MAKING PREDICTIONS EQUALLY IN

6456
03:57:05,328 --> 03:57:07,164
ALL PEOPLE REGARDLESS OF THEIR

6457
03:57:07,164 --> 03:57:07,597
BACKGROUND.

6458
03:57:07,597 --> 03:57:08,899
SO ABSOLUTELY IT'S VERY

6459
03:57:08,899 --> 03:57:10,534
IMPORTANT AND I WOULD SAY

6460
03:57:10,534 --> 03:57:12,369
UNDERSTUDIED AREA OF AI.

6461
03:57:12,369 --> 03:57:13,904
>> OKAY, YEAH, GREAT, I AM

6462
03:57:13,904 --> 03:57:16,039
WORKING WITH A DOCTORAL STUDENT

6463
03:57:16,039 --> 03:57:21,812
AND THERE ARE MORE EXPERTS IN

6464
03:57:21,812 --> 03:57:23,513
THE TEAM LOOKING FOR FENDOEE

6465
03:57:23,513 --> 03:57:26,349
TYPE AND FAIRNESS IN EHR DATA SO

6466
03:57:26,349 --> 03:57:27,517
IT WAS, ANYWAY, WONDERFUL TO

6467
03:57:27,517 --> 03:57:38,028
HEAR ALL YOUR TALKS TODAY, SO

6468
03:57:41,231 --> 03:57:42,032
THANK YOU.

6469
03:57:42,032 --> 03:57:43,300
>> HI, DAN WITH THE
MEDICAL

6470
03:57:43,300 --> 03:57:44,835
CENTER, THIS WAS A QUESTION THAT

6471
03:57:44,835 --> 03:57:46,236
GOES OUT TO SPEAKERS HERE, I

6472
03:57:46,236 --> 03:57:48,638
THINK IT WOULD BE REALLY USEFUL

6473
03:57:48,638 --> 03:57:51,308
TO SORT OF YOU KNOW, WE HEARD

6474
03:57:51,308 --> 03:57:55,278
SOME EXAMPLES OF, YOU KNOW ARE

6475
03:57:55,278 --> 03:57:58,415
WHERE LLMs MIGHT   PERFORM

6476
03:57:58,415 --> 03:58:00,383
WELL FROM IT IS PERSPECTIVE OF

6477
03:58:00,383 --> 03:58:02,586
USER THAT IS NOT NECESSARILY A

6478
03:58:02,586 --> 03:58:04,020
RESEARCHER, WONDERING IF YOU

6479
03:58:04,020 --> 03:58:07,791
COULD COMMENT ON YOUR

6480
03:58:07,791 --> 03:58:09,826
EXPERIENCES IN THE FIELD AND

6481
03:58:09,826 --> 03:58:11,561
WHAT AREAS MAYBE TO HEALTHCARE

6482
03:58:11,561 --> 03:58:14,231
RECORD SYSTEMS WHAT KIND OF

6483
03:58:14,231 --> 03:58:16,833
TASKS ARE LMM GOOD FOR AND AS

6484
03:58:16,833 --> 03:58:27,277
OPPOSED TO STAY AWAY FROM?

6485
03:58:29,546 --> 03:58:31,715
>> YOUR QUESTION IS GREAT,
THE

6486
03:58:31,715 --> 03:58:32,983
PROBLEM APPLIES WHEN LLMs

6487
03:58:32,983 --> 03:58:34,151
TRAIN ON WHAT THEY HAVE ON THE

6488
03:58:34,151 --> 03:58:35,352
BRETT AND THEY ONLY KNOW WHAT

6489
03:58:35,352 --> 03:58:37,187
THEY'VE BEEN TRAINED ON AND IF

6490
03:58:37,187 --> 03:58:39,823
YOU'RE TRYING TO APPLY THEM TO A

6491
03:58:39,823 --> 03:58:41,124
VERY SPECIFIC TASK, THAT WASN'T

6492
03:58:41,124 --> 03:58:42,292
IN THE TRAINING SET, THAT'S

6493
03:58:42,292 --> 03:58:43,360
WHERE YOU WILL HAVE PROBLEMS AND

6494
03:58:43,360 --> 03:58:45,195
SO FOR THOSE OF YOU ON THE CALL

6495
03:58:45,195 --> 03:58:47,964
THAT AREN'T EXPERTS IN LARGE

6496
03:58:47,964 --> 03:58:50,133
LANGUAGE MODELS THERE'S

6497
03:58:50,133 --> 03:58:51,535
SOMETHING CALLED RETRIEVAL

6498
03:58:51,535 --> 03:58:54,804
AUGMENTED GENERATION OR RAG FOR

6499
03:58:54,804 --> 03:58:55,105
SHORT.

6500
03:58:55,105 --> 03:59:00,076
WHICH IS CREATING A DATABASE

6501
03:59:00,076 --> 03:59:01,244
WHERE YOU PUT INFORMATION AND

6502
03:59:01,244 --> 03:59:02,412
LANGUAGE THAT YOU MIGHT NOT HAVE

6503
03:59:02,412 --> 03:59:04,915
ACCESS TO AND THERE ARE TRICKS

6504
03:59:04,915 --> 03:59:07,050
YOU CAN DO TO WHEN YOU GIVE IT A

6505
03:59:07,050 --> 03:59:08,985
PROMPT TO MATCH IT TO THE

6506
03:59:08,985 --> 03:59:10,854
DATABASE AND THEN FEED THE RIGHT

6507
03:59:10,854 --> 03:59:12,923
INFORMATION TO CHAT GPT OR LARGE

6508
03:59:12,923 --> 03:59:15,192
LANGUAGE MODEL SO IT CAN CRAFT A

6509
03:59:15,192 --> 03:59:15,926
MORE ACCURATERY SPONSE BUT IN

6510
03:59:15,926 --> 03:59:20,564
THE END OF IT, THAT'S 1 OF THE

6511
03:59:20,564 --> 03:59:22,432
THINGS WE DO IS PUT

6512
03:59:22,432 --> 03:59:27,571
BIOMALKNOWLEDGE INTO A RAG

6513
03:59:27,571 --> 03:59:29,306
DATABASE AND GIVE CHAT GPT

6514
03:59:29,306 --> 03:59:31,641
ACCESS TO ALL THESE

6515
03:59:31,641 --> 03:59:32,976
RELATIONSHIPS BETWEEN GENES AND

6516
03:59:32,976 --> 03:59:35,912
DRUGS AND DISEASE, AND ONLY THEN

6517
03:59:35,912 --> 03:59:40,217
IN THE OTHER TRICKS IN PAPER,

6518
03:59:40,217 --> 03:59:43,186
ONLY THEN DOES CHAT GPT DO A

6519
03:59:43,186 --> 03:59:48,058
GOOD JOB SCWRING AND MUCH LESS

6520
03:59:48,058 --> 03:59:48,592
LIKELY TO HALLUCINATE.

6521
03:59:48,592 --> 03:59:50,560
SO I WOULD SAY OUT OF THE BOX

6522
03:59:50,560 --> 03:59:56,800
THEY DO MAKE MISTAKES AND THEY

6523
03:59:56,800 --> 03:59:59,402
ARE INACCURATE PLENTY OF TIMES.

6524
03:59:59,402 --> 04:00:01,271
AND JUST A FUNNY EXAMPLE, I WILL

6525
04:00:01,271 --> 04:00:03,039
SKIP IT BUT I DON'T WANT TO GET

6526
04:00:03,039 --> 04:00:04,674
INTO IT -- SO ANYWAY, I THINK

6527
04:00:04,674 --> 04:00:06,176
THERE ARE SPECIFIC THINGS CAN

6528
04:00:06,176 --> 04:00:09,112
YOU DO TO GET THEM TO WORK MUCH

6529
04:00:09,112 --> 04:00:10,547
BETTER ON RESEARCH TYPE

6530
04:00:10,547 --> 04:00:14,684
PROBLEMS, AND OTHER CLINICAL

6531
04:00:14,684 --> 04:00:14,951
PROBLEMS.

6532
04:00:14,951 --> 04:00:17,754
I CAN GIVE MY EXPERIENCE AS PART

6533
04:00:17,754 --> 04:00:20,123
OF OUR WORK AT THE NEW YORK

6534
04:00:20,123 --> 04:00:21,157
PRESCRIBING BI TERRION HOSPITAL

6535
04:00:21,157 --> 04:00:24,394
WHERE WE THINK OF LPLRKS Ms ON

6536
04:00:24,394 --> 04:00:25,795
CLINICAL DOCUMENTATION AND TEXT

6537
04:00:25,795 --> 04:00:26,997
BUT ALSO FOUNDATION MODELS ON

6538
04:00:26,997 --> 04:00:29,933
OTHER TYPE OF DATA TYPES, RIGHT,

6539
04:00:29,933 --> 04:00:31,534
SO WHENEVER WE SAY LARGE

6540
04:00:31,534 --> 04:00:33,603
LANGUAGE MODEL, IT'S THE

6541
04:00:33,603 --> 04:00:34,437
ORIGINAL TECHNOLOGY, BUT

6542
04:00:34,437 --> 04:00:39,242
LANGUAGE COULD BE REPLACED AND

6543
04:00:39,242 --> 04:00:48,118
WE FIND IN GENERAL THAT THESE

6544
04:00:48,118 --> 04:00:49,653
LANGUAGE, AND USE OTHER THINGS,

6545
04:00:49,653 --> 04:00:51,821
YOU CAN BUILD TECHNOLOGIES

6546
04:00:51,821 --> 04:00:53,556
THAT'S VERY HELPFUL TO ALL

6547
04:00:53,556 --> 04:00:54,724
STAKEHOLDERS IN THE HEALTH

6548
04:00:54,724 --> 04:01:00,730
SYSTEM. 

6549
04:01:00,730 --> 04:01:04,768
SO WE'RE RIGHT NOW AND REALLY

6550
04:01:04,768 --> 04:01:08,004
HEAR THE QUESTION IS NOT EVEN

6551
04:01:08,004 --> 04:01:10,307
HOW WELL IS IT DOING BUT WE CAN

6552
04:01:10,307 --> 04:01:11,941
VALIDATE THAT TO SOME EXTENT BUT

6553
04:01:11,941 --> 04:01:13,109
IT'S REALLY WHAT DO PEOPLE ASK

6554
04:01:13,109 --> 04:01:14,377
ONCE THEY HAVE THE ABILITY TO

6555
04:01:14,377 --> 04:01:24,888
ASK ANY QUESTION OF A PATIENT

6556
04:01:53,516 --> 04:01:53,917
RECORD, RIGHT?

6557
04:01:53,917 --> 04:01:56,152
-- POEM DON'T WANT TO SHARE

6558
04:01:56,152 --> 04:01:56,820
THEIR MENSTRUAL HEALTH DATA BUT

6559
04:01:56,820 --> 04:01:58,855
APPROXIMATE WE ARE ABLE TO

6560
04:01:58,855 --> 04:01:59,789
GENERATE FAKE MENSTRUAL HEALTH

6561
04:01:59,789 --> 04:02:01,891
DATA THAT LOOKS A LOT LIKE WHAT

6562
04:02:01,891 --> 04:02:03,593
MEN STRAIGHTERS TELL US ABOUT

6563
04:02:03,593 --> 04:02:04,527
THEIR MENSTRUATION THEN THAT

6564
04:02:04,527 --> 04:02:07,931
COULD BE HELPFUL TO YOU KNOW

6565
04:02:07,931 --> 04:02:09,232
GIVE TO THE RESEARCH COMMUNITY

6566
04:02:09,232 --> 04:02:11,301
AND UNLOCK A LOT OF RESEARCH ON

6567
04:02:11,301 --> 04:02:21,778
A TOPIC THAT'S NOT CURRENTLY

6568
04:02:36,526 --> 04:02:36,926
VERY STUDIED.

6569
04:02:36,926 --> 04:02:38,194
>> -- INFORMATION YOU CAN
BE

6570
04:02:38,194 --> 04:02:39,229
REASONABLY SURE THAT INFORMATION

6571
04:02:39,229 --> 04:02:42,866
IS CORRECT IS 1 THING, WE HAVE A

6572
04:02:42,866 --> 04:02:44,534
PROJECT WHERE WE'RE JUST TRYING

6573
04:02:44,534 --> 04:02:46,136
TO IDENTIFY INSTANCES OF DATA

6574
04:02:46,136 --> 04:02:54,110
REUSE IN THE LITERATURE WE WOULD

6575
04:02:54,110 --> 04:02:55,412
NECESSARILY RECOGNIZE AT THE

6576
04:02:55,412 --> 04:02:58,782
BEGINNING SO HUMANS CAN DO THAT,

6577
04:02:58,782 --> 04:02:59,783
TRADITIONAL STATISTICAL METHODS

6578
04:02:59,783 --> 04:03:00,617
CAN DO THAT, LENS LENS LENS LENS

6579
04:03:00,617 --> 04:03:01,551
MENTORSHIP SKILLS KIND OF MAKE

6580
04:03:01,551 --> 04:03:04,854
STUFF UP AND WE HAVE BEEN

6581
04:03:04,854 --> 04:03:06,156
TRAINING AND DOING IT AROUND

6582
04:03:06,156 --> 04:03:07,457
THIS BUT IT'S TRICKY, IT'S NOT

6583
04:03:07,457 --> 04:03:08,958
CLEAR TO ME THAT MAYBE IS LIKE

6584
04:03:08,958 --> 04:03:16,566
THE BEST FIT FOR THAT PROBLEM

6585
04:03:16,566 --> 04:03:16,766
SPACE.

6586
04:03:16,766 --> 04:03:18,334
AND O THE TYPE OF QUESTION YOU

6587
04:03:18,334 --> 04:03:19,869
HAVE DEPENDS ON THE DATA YOU

6588
04:03:19,869 --> 04:03:26,342
HAVE TO VALIDATE AND I WANT TO

6589
04:03:26,342 --> 04:03:27,644
EMPHASIZE ON THIS, THEY'RE NOT

6590
04:03:27,644 --> 04:03:33,450
THINKING, THEY'RE JUST

6591
04:03:33,450 --> 04:03:34,117
PREDICTING PROBABLISTICALLY WHAT

6592
04:03:34,117 --> 04:03:35,318
THEY'RE SAYING, AND YOU CAN

6593
04:03:35,318 --> 04:03:36,753
SPEND AS MUCH TIME CREATING

6594
04:03:36,753 --> 04:03:38,254
DATABASES TO MAKE SURE IT'S

6595
04:03:38,254 --> 04:03:39,289
PULLING IN SOMETHING CORRECT AS

6596
04:03:39,289 --> 04:03:41,491
YOU MIGHT JUST LIKE WRITING SOME

6597
04:03:41,491 --> 04:03:43,793
OTHER CODE OR STATISTICAL MODEL

6598
04:03:43,793 --> 04:03:45,295
TO SOLVING PROBLEMS SO IT GETS

6599
04:03:45,295 --> 04:03:47,063
LIKE TO BEING INTENTIONAL AND

6600
04:03:47,063 --> 04:03:48,064
THINKING THROUGH WHAT TOOLS ARE

6601
04:03:48,064 --> 04:03:53,303
THE RIGHT 1 FOR THE JOB THAT WE

6602
04:03:53,303 --> 04:03:55,872
ARE TRYING TO DO AND I THINK WE

6603
04:03:55,872 --> 04:04:06,349
WILL BE PHENOMENAL FOR DATA

6604
04:04:13,156 --> 04:04:13,790
RECOVERY AND RESEARCH.

6605
04:04:13,790 --> 04:04:15,358
AND THEN SOMEBODY I WORK WITH

6606
04:04:15,358 --> 04:04:20,964
HAS BUILT LIKE A IF YOU ARE ALL

6607
04:04:20,964 --> 04:04:22,732
WITH AGENTS AND LLMs PULLING

6608
04:04:22,732 --> 04:04:24,934
IN DATA FROM DIFFERENT SOURS

6609
04:04:24,934 --> 04:04:26,769
CONSTRUCTING A RELATIONAL SORT

6610
04:04:26,769 --> 04:04:31,875
OF KNOWLEDGE GRAPH SITTING

6611
04:04:31,875 --> 04:04:34,043
BEHIND IT THAT AND BED HOW THIS

6612
04:04:34,043 --> 04:04:34,844
RESOURCE IS THINKING ABOUT THESE

6613
04:04:34,844 --> 04:04:36,646
THINGS THAT ARE RELATED SO

6614
04:04:36,646 --> 04:04:38,314
THERE'S A HUMAN VALIDATING AND I

6615
04:04:38,314 --> 04:04:39,916
THINK THE NEXT GENERATION OF

6616
04:04:39,916 --> 04:04:41,417
TOOLS AND IRPT FACES TO DATA

6617
04:04:41,417 --> 04:04:43,920
THAT WE CAN BUILD WITH SOMETHING

6618
04:04:43,920 --> 04:04:45,188
SO POWERFUL IT'S SYNTHESIZING

6619
04:04:45,188 --> 04:04:46,389
AND BRINGING PEOPLE TOGETHER IS

6620
04:04:46,389 --> 04:04:47,524
SUPER EXCITING AND IT'S JUST

6621
04:04:47,524 --> 04:04:54,097
MAKING SURE IT'S BEING USED FOR

6622
04:04:54,097 --> 04:04:55,398
THE RIGHT PURPOSE.

6623
04:04:55,398 --> 04:04:56,432
THANKS FOR AGAIN ADVOCATING IF

6624
04:04:56,432 --> 04:04:57,267
ARE A HUMAN IN THE LIMITED

6625
04:04:57,267 --> 04:04:59,335
PARTNER AND MY QUESTION IS TO

6626
04:04:59,335 --> 04:05:04,307
DR. MOORE IS THAT IN CLINICAL

6627
04:05:04,307 --> 04:05:05,642
USAGE CLINICAL DECISION SUPPORT

6628
04:05:05,642 --> 04:05:07,443
IS SO IMPORTANT AND STILL TO

6629
04:05:07,443 --> 04:05:10,813
HAVE HUMAN IN THE LOOP TO BE THE

6630
04:05:10,813 --> 04:05:12,549
DECISION MAKER, YOU'RE NODDING

6631
04:05:12,549 --> 04:05:20,690
YOUR HEAD, I'M ASSUMING YOU'RE

6632
04:05:20,690 --> 04:05:23,359
AGREEING AND THEIR SITUATION I

6633
04:05:23,359 --> 04:05:33,903
THINK I CAN SIGN OUT OF THE LOOP

6634
04:05:35,138 --> 04:05:35,505
NOW.

6635
04:05:35,505 --> 04:05:38,308
ONE OF THE BOARD MEMBERS ASK

6636
04:05:38,308 --> 04:05:48,818
IFED WE WERE USING AND SO PUT

6637
04:05:50,019 --> 04:05:52,722
THAT TO BED VERY QUICKLY, AS A

6638
04:05:52,722 --> 04:05:55,224
HOSPITAL, WE FIRMLY BELIEVE THAT

6639
04:05:55,224 --> 04:05:56,526
OUR CLINICIANS ARE THE 1S THAT

6640
04:05:56,526 --> 04:05:58,528
MAKE THE DECISIONS AND WE SEE AI

6641
04:05:58,528 --> 04:06:00,496
AS ASSISTANCE TO GIVE ADVICE AND

6642
04:06:00,496 --> 04:06:04,067
HELP MAKE DECISIONS BUT NOT BE

6643
04:06:04,067 --> 04:06:13,876
THE DECISION MAKERS.

6644
04:06:13,876 --> 04:06:15,678
QUESTIONS FROM THE AUDIENCE, I

6645
04:06:15,678 --> 04:06:21,818
DON'T WANT TO DOMINATE THE

6646
04:06:21,818 --> 04:06:22,485
QUESTIONS.

6647
04:06:22,485 --> 04:06:23,853
>> WHILE WE'RE WAITING ON

6648
04:06:23,853 --> 04:06:26,289
QUESTIONS I WANT TO MENTION

6649
04:06:26,289 --> 04:06:28,324
AGENT AI AND FOR THOSE WHO

6650
04:06:28,324 --> 04:06:29,592
HAVEN'T HEARD IT, AGENETICALLYIC

6651
04:06:29,592 --> 04:06:31,961
AI IS SOMETHING THAT'S BECOMING

6652
04:06:31,961 --> 04:06:34,631
HOT AND USEFUL AND THE BASIC

6653
04:06:34,631 --> 04:06:37,634
IDEA IS TO HAVE MULTIPLE AI

6654
04:06:37,634 --> 04:06:39,769
AGENTS THAT TACKLE INDEPENDENTLY

6655
04:06:39,769 --> 04:06:41,170
INDEPENDENT PARTS OF A PROBLEM

6656
04:06:41,170 --> 04:06:43,206
AND SOLVE A BIGGER PROBLEM AND

6657
04:06:43,206 --> 04:06:44,841
EXAMPLE I WAS LISTENING TO A

6658
04:06:44,841 --> 04:06:46,442
PODCAST AND IT WAS A GREAT

6659
04:06:46,442 --> 04:06:49,479
EXAMPLE OF A HIGH SCHOOL STUDENT

6660
04:06:49,479 --> 04:06:52,248
CHEATING ON HOME WORK USING AI

6661
04:06:52,248 --> 04:06:54,317
AND HE DEVELOPED AN APPROACH

6662
04:06:54,317 --> 04:06:55,718
THAT WOULD WRITE THE ESSAY FOR

6663
04:06:55,718 --> 04:06:58,087
HIM AND ANOTHER AI THAT WOULD

6664
04:06:58,087 --> 04:07:00,356
EDIT IT AND ANOTHER AI WOULD

6665
04:07:00,356 --> 04:07:02,959
CHANGE THE LANGUAGE THAT A

6666
04:07:02,959 --> 04:07:03,660
LANGUAGE DETECTION ALGORITHM

6667
04:07:03,660 --> 04:07:05,762
WOULD BT KNOW IT WAS WRITTEN BY

6668
04:07:05,762 --> 04:07:08,431
AI AND WAS A CLEAR EXAMPLE OF

6669
04:07:08,431 --> 04:07:09,899
AGENETICALLYIC AI AND I WANT TO

6670
04:07:09,899 --> 04:07:14,871
SHOW IT OUT THERE BECAUSE MY THE

6671
04:07:14,871 --> 04:07:17,840
END OF YEAR AGENTIC AI, AND 2025

6672
04:07:17,840 --> 04:07:20,410
WILL BE THE YEAR OF AGENTIC AI

6673
04:07:20,410 --> 04:07:22,779
AND THEY WILL GIVE US AN

6674
04:07:22,779 --> 04:07:23,946
IMPROVED LEVEL OF PERFORMANCE

6675
04:07:23,946 --> 04:07:25,248
WITH LARGE LANGUAGE MODELS AND

6676
04:07:25,248 --> 04:07:26,783
EVEN DEEP LEARNING AND

6677
04:07:26,783 --> 04:07:28,618
REINFORCEMENT LEARNING AND OTHER

6678
04:07:28,618 --> 04:07:30,019
TYPES OF AI ABOVE AND BEYOND

6679
04:07:30,019 --> 04:07:40,430
WHAT WE'RE DOING NOW USING

6680
04:07:40,430 --> 04:07:41,330
SINGLE AI APPROACHES.

6681
04:07:41,330 --> 04:07:43,700
AND I WILL REFERENCE ANOTHER

6682
04:07:43,700 --> 04:07:47,003
ARTICLE THAT INVOLVES A COMPANY

6683
04:07:47,003 --> 04:07:50,973
SUGGESTING IT WAS USING AGENTIC

6684
04:07:50,973 --> 04:07:53,476
AI TO FILL IT OUT AND SELL IT

6685
04:07:53,476 --> 04:07:56,312
AND IT TURNS OUT IT WAS BEING

6686
04:07:56,312 --> 04:07:58,514
SOLD TO 700 PEOPLE IN ANOTHER

6687
04:07:58,514 --> 04:08:00,016
COUNTRY DOING THE WORK SO

6688
04:08:00,016 --> 04:08:01,017
THERE'S LOTS OF CRITICAL

6689
04:08:01,017 --> 04:08:02,218
THINKING AND READING TO DO AND

6690
04:08:02,218 --> 04:08:12,495
IT IS SUPER FUN.

6691
04:08:13,663 --> 04:08:16,632
MY OFFICE HAS A SIZABLE

6692
04:08:16,632 --> 04:08:19,902
INITIATIVE, AND MULTIMODAL AI,

6693
04:08:19,902 --> 04:08:25,475
AND IT IS STILL AT THE RESEARCH

6694
04:08:25,475 --> 04:08:27,410
STAGE, DO YOU SEE DO YOU SEE THE

6695
04:08:27,410 --> 04:08:29,846
QUESTION FOR ALL 3 OF YOU,

6696
04:08:29,846 --> 04:08:31,914
HAVING MULTIMODAL AI IN A

6697
04:08:31,914 --> 04:08:42,425
CLINICAL CONTEXT IN MEDICINE?

6698
04:08:48,998 --> 04:08:51,567
A LAB TEST THAT TIME SERIES IS

6699
04:08:51,567 --> 04:08:52,802
MULTIMODAL COMPARED TO CLINICAL

6700
04:08:52,802 --> 04:08:53,903
DOCUMENTATION, SO YOU KNOW I

6701
04:08:53,903 --> 04:08:56,739
THINK WE WANT TO BE BROADER,

6702
04:08:56,739 --> 04:08:58,341
WHEN WE THINK ABOUT MULTIMODAL,

6703
04:08:58,341 --> 04:09:02,712
BUT I THINK THAT'S A HOPE AND WE

6704
04:09:02,712 --> 04:09:05,114
KNOW THAT YOU KNOW THERE'S THIS

6705
04:09:05,114 --> 04:09:06,916
NEW DATA TYPES LIKE WEARABLES,

6706
04:09:06,916 --> 04:09:09,418
AND THINGS THAT ARE NOT EVEN YET

6707
04:09:09,418 --> 04:09:11,053
FULLY PART OF THE HEALTHCARE

6708
04:09:11,053 --> 04:09:12,655
SYSTEM, WE WANT TO BE ABLE TO

6709
04:09:12,655 --> 04:09:15,124
INTORPERATE THEM, BUT WE KNOW

6710
04:09:15,124 --> 04:09:16,692
THAT WHEN WE ASK HUMANS TO DO

6711
04:09:16,692 --> 04:09:18,761
SO, IT'S A WHOLE LOT OF WORK AND

6712
04:09:18,761 --> 04:09:20,029
SO, YOU KNOW IS IT SOMETHING

6713
04:09:20,029 --> 04:09:22,665
THAT AI CAN HELP WITH, AND I

6714
04:09:22,665 --> 04:09:25,067
THINK IT CAN, AND PROBABLY

6715
04:09:25,067 --> 04:09:26,002
FOUNDATION MODELS WILL BE YOU

6716
04:09:26,002 --> 04:09:30,673
KNOW A WAY TO GET THERE TO THIS

6717
04:09:30,673 --> 04:09:32,241
MULTIMODEL ASPECT WHERE IT CAN

6718
04:09:32,241 --> 04:09:33,743
LEARN A REPRESENTATION OF EACH

6719
04:09:33,743 --> 04:09:36,679
OF THESE MODALITIES AND BASED ON

6720
04:09:36,679 --> 04:09:41,417
THE TASK KIND OF BE SMART ABOUT

6721
04:09:41,417 --> 04:09:42,919
WHICH MODALITY TO PAY ATTENTION,

6722
04:09:42,919 --> 04:09:44,353
TO HOW TO INTEGRATE THEM, ET

6723
04:09:44,353 --> 04:09:44,587
CETERA.

6724
04:09:44,587 --> 04:09:47,156
BUT I THINK THE UNIFIER HERE OR

6725
04:09:47,156 --> 04:09:57,600
THE HARMONIZER WILL BE THE

6726
04:09:59,068 --> 04:10:00,136
FOUNDATION MODELS PROBABLY.

6727
04:10:00,136 --> 04:10:02,104
SO TALKING GENOMIC AND

6728
04:10:02,104 --> 04:10:02,772
HISTOPATHOLOGY, BUT YESTERDAY,

6729
04:10:02,772 --> 04:10:04,106
AT THE CONFERENCE HERE, I ALSO

6730
04:10:04,106 --> 04:10:07,343
HEARD THE USE OF MULTIMODAL,

6731
04:10:07,343 --> 04:10:11,414
APPLYING TO DIFFERENT DATA FROM

6732
04:10:11,414 --> 04:10:12,415
DIFFERENT CELL TYPES.

6733
04:10:12,415 --> 04:10:16,452
WITHIN AN ORGANISM SO YOU'RE

6734
04:10:16,452 --> 04:10:18,187
RIGHT IN POINTING OUT THAT WOULD

6735
04:10:18,187 --> 04:10:20,456
NOT HAVE NORMALLY THOUGHT OF

6736
04:10:20,456 --> 04:10:22,859
DIFFERENT DATA FROM SEQUENCING

6737
04:10:22,859 --> 04:10:24,360
DATA FROM THE SAMPLE FROM

6738
04:10:24,360 --> 04:10:32,001
DEFINITE CELLS WITHIN AN

6739
04:10:32,001 --> 04:10:35,705
ORGANISM AS MULTIMODAL BUT IT

6740
04:10:35,705 --> 04:10:37,206
OPENED MY EYES ABOUT WHAT WE

6741
04:10:37,206 --> 04:10:38,608
SHOULD THINK BROADLY ABOUT

6742
04:10:38,608 --> 04:10:39,242
MULTIMODAL.

6743
04:10:39,242 --> 04:10:43,746
LET ME SEE, I AM CONSCIOUS OF

6744
04:10:43,746 --> 04:10:45,448
NOT IGNORING QUESTIONS THAT MAY

6745
04:10:45,448 --> 04:10:47,383
BE IN THE CHAT.

6746
04:10:47,383 --> 04:10:57,660
I DON'T SEE ANY.

6747
04:11:16,445 --> 04:11:17,813
>> IT'S ACTUALLY JANINE'S
TURN?

6748
04:11:17,813 --> 04:11:25,187
SO THERE YOU GO.

6749
04:11:25,187 --> 04:11:26,956
>> WHAT A FANTASTIC SET OF

6750
04:11:26,956 --> 04:11:31,027
PRESENTATIONS AND PANEL

6751
04:11:31,027 --> 04:11:31,327
DISCUSSIONS.

6752
04:11:31,327 --> 04:11:32,595
WE WERE REALLY EXCITED TO HAVE

6753
04:11:32,595 --> 04:11:35,898
THIS SESSION AND WE WERE ON

6754
04:11:35,898 --> 04:11:37,400
TARGET SO I APPRECIATE YOU

6755
04:11:37,400 --> 04:11:39,502
COMING TOGETHER AND COMING INTO

6756
04:11:39,502 --> 04:11:43,572
THIS MAYBE A LITTLE UNFAMILIAR

6757
04:11:43,572 --> 04:11:44,974
SPACE EXCEPT FOR THE THINGS WE

6758
04:11:44,974 --> 04:11:46,042
TALKED ABOUT BEFORE TO TALK

6759
04:11:46,042 --> 04:11:48,444
ABOUT THE POWER OF THE

6760
04:11:48,444 --> 04:11:52,281
POTENTIAL, THE PIT FALLS, THE

6761
04:11:52,281 --> 04:11:53,349
PRIVACY AND MANY OTHER PIECES

6762
04:11:53,349 --> 04:11:56,452
THAT WERE INVOLVED IN TRYING TO

6763
04:11:56,452 --> 04:11:58,621
THINK THROUGH ACCOUNTING FOR SEX

6764
04:11:58,621 --> 04:12:01,590
AS A BIOLOGICAL VARIABLE FROM MY

6765
04:12:01,590 --> 04:12:04,360
PERSPECTIVE IN AI AND PUTTING

6766
04:12:04,360 --> 04:12:05,428
SCIENCE AND TECHNOLOGY AND

6767
04:12:05,428 --> 04:12:06,362
INNOVATION TO WORK FOR THE

6768
04:12:06,362 --> 04:12:07,730
HEALTH OF WOMEN BECAUSE THAT'S

6769
04:12:07,730 --> 04:12:10,266
WHY WE ARE HERE, THAT'S OUR WHY

6770
04:12:10,266 --> 04:12:13,102
AND SO WE'RE GREATLY

6771
04:12:13,102 --> 04:12:14,136
APPRECIATIVE OF YOUR INPUT ON

6772
04:12:14,136 --> 04:12:15,338
THAT CONVERSATION TODAY AND WITH

6773
04:12:15,338 --> 04:12:17,807
THAT WE ACTUALLY ARE SUPPOSED TO

6774
04:12:17,807 --> 04:12:19,942
HAVE ANOTHER 5 MINUTES OF OPEN

6775
04:12:19,942 --> 04:12:22,178
DISCUSSION, THANK YOU SO MUCH

6776
04:12:22,178 --> 04:12:23,346
PANEL, WELCOME TO STAY BUT I

6777
04:12:23,346 --> 04:12:24,180
KNOW YOU'RE ALL BUSY

6778
04:12:24,180 --> 04:12:25,281
SOPHISTICATEDY WE WISH YOU WELL.

6779
04:12:25,281 --> 04:12:27,950
WE ARE SUPPOSED TO HAVE 5

6780
04:12:27,950 --> 04:12:29,585
MINUTES OF OPEN DISCUSSION FOR

6781
04:12:29,585 --> 04:12:31,487
ADVISORY MEMBERS AT THIS TIME

6782
04:12:31,487 --> 04:12:34,857
TELL 2:15 SO I WANT TO HOPE THE

6783
04:12:34,857 --> 04:12:36,525
FLOOR AGAIN FOR ADVISORY

6784
04:12:36,525 --> 04:12:37,326
COMMITTEE MEMBERS, PERHAPS YOU

6785
04:12:37,326 --> 04:12:40,062
THOUGHT ABOUT SOMETHING ON THE

6786
04:12:40,062 --> 04:12:40,696
BREAK OR LUNCH RATHER, ABOUT

6787
04:12:40,696 --> 04:12:42,331
THAT YOU WANTED TO BRING UP AS A

6788
04:12:42,331 --> 04:12:48,004
TOPIC FOR US TO CONSIDER FOR

6789
04:12:48,004 --> 04:12:48,604
FUTURE MEETINGS. 

6790
04:12:48,604 --> 04:12:55,378
OR A QUESTION.

6791
04:12:55,378 --> 04:12:57,813
AND IF NOT I HAVE AN EXCITING

6792
04:12:57,813 --> 04:12:58,881
LATE BREAKING ANNOUNCEMENT FOR

6793
04:12:58,881 --> 04:13:01,484
YOU, WE ARE REALLY THRILLED TO

6794
04:13:01,484 --> 04:13:02,551
ANNOUNCE THAT WE'RE -- THROUGH

6795
04:13:02,551 --> 04:13:04,420
OUR COMMITMENT TO ADVANCING

6796
04:13:04,420 --> 04:13:06,956
WOMEN'S HEALTH HERE AT NIH,

6797
04:13:06,956 --> 04:13:09,792
THROUGH ROBUST, TRANSPARENT AND

6798
04:13:09,792 --> 04:13:10,559
ACCOUNTABLE SCIENTIFIC

6799
04:13:10,559 --> 04:13:12,595
INVESTMENT, THAT BEGINNING WITH

6800
04:13:12,595 --> 04:13:16,832
THE FY24 REPORTING CYCLE, NIH

6801
04:13:16,832 --> 04:13:18,801
HAS CONVERTED OUR RCDC SYSTEM,

6802
04:13:18,801 --> 04:13:20,870
IT STAND FIST ARE RESEARCH

6803
04:13:20,870 --> 04:13:23,005
CONDITION AND DISEASE

6804
04:13:23,005 --> 04:13:23,539
CATEGORIZATION, REPORTING

6805
04:13:23,539 --> 04:13:24,874
METHODOLOGY FOR THE WOMEN'S

6806
04:13:24,874 --> 04:13:26,275
HEALTH RESEARCH CATEGORY FOR A

6807
04:13:26,275 --> 04:13:28,611
MANUEL CODING TO A FULLY

6808
04:13:28,611 --> 04:13:29,545
AUTOMATED CODING.

6809
04:13:29,545 --> 04:13:31,881
TO ENHANCE OUR ACCURACY AND

6810
04:13:31,881 --> 04:13:32,381
CONSISTENCY.

6811
04:13:32,381 --> 04:13:35,451
SO THE PREVIOUS CATEGORIES, FOR

6812
04:13:35,451 --> 04:13:41,290
WOMEN'S HEALTH, MANUELLY,

6813
04:13:41,290 --> 04:13:43,826
CURATED, THE NEW CATTED GORY IS

6814
04:13:43,826 --> 04:13:45,728
CALLED WOMEN'S RESEARCH, AND

6815
04:13:45,728 --> 04:13:48,631
UNDER IT THERE WERE PROJECTS

6816
04:13:48,631 --> 04:13:50,800
ENCLUED THAD DID NOT DIRECTLY

6817
04:13:50,800 --> 04:13:52,201
FOCUS ON WOMEN'S HEALTH OUTCOMES

6818
04:13:52,201 --> 04:13:54,837
HOWEVER THE NEW AUTOMATED SYSTEM

6819
04:13:54,837 --> 04:13:56,405
INSURES A MORE RECISE REFLECTION

6820
04:13:56,405 --> 04:13:57,873
OF OUR RESEARCH EFFORTS AND

6821
04:13:57,873 --> 04:13:59,742
SUPPORTING A MORE EFFECTIVE USE

6822
04:13:59,742 --> 04:14:00,709
OF TAXPAYER DOLLARS, SO I DO

6823
04:14:00,709 --> 04:14:02,311
WANT TO SHARE WITH YOU THAT YOU

6824
04:14:02,311 --> 04:14:04,613
MAY NOTICE SOME DIFFERENCES IN

6825
04:14:04,613 --> 04:14:07,016
THE NUMBERS, WHILE THE UPDATED

6826
04:14:07,016 --> 04:14:09,552
METHODOLOGY MAY SHOW AN APPARENT

6827
04:14:09,552 --> 04:14:16,125
DECREASE IN THE REPORTED FUNDING

6828
04:14:16,125 --> 04:14:19,328
DOLLARS FROM FY23 TO FY24.

6829
04:14:19,328 --> 04:14:20,896
OVERALL FUNDING FOR WOMEN'S

6830
04:14:20,896 --> 04:14:22,431
HEALTH RESEARCH HAS NOT CHANGED.

6831
04:14:22,431 --> 04:14:23,833
THE SHIFT IS RELATED TO

6832
04:14:23,833 --> 04:14:27,002
PROVIDING A CLEAR AND MORE

6833
04:14:27,002 --> 04:14:28,471
ACCURATE REPRESENTATION OF OUR

6834
04:14:28,471 --> 04:14:31,240
SUSTAINED INVESTMENT IN THIS

6835
04:14:31,240 --> 04:14:32,441
CRITICAL INVESTMENT, AND IT'S

6836
04:14:32,441 --> 04:14:34,643
HOW IT'S REPORTED, NOT THE

6837
04:14:34,643 --> 04:14:41,717
AMOUNT THAT'S BEING FUNDED, IT'S

6838
04:14:41,717 --> 04:14:42,751
THE REPORTING METHODOLOGY, I DO

6839
04:14:42,751 --> 04:14:45,154
WANT TO SEE HOW RNT THIS IS, IN

6840
04:14:45,154 --> 04:14:47,690
RESEARCH SPENDING AND A PULLEY

6841
04:14:47,690 --> 04:14:48,757
AUTOMATED WOMEN'S HEALTH

6842
04:14:48,757 --> 04:14:50,159
RESEARCH CATEGORY THROUGH RCDC

6843
04:14:50,159 --> 04:14:51,894
IS SOMETHING WE HAVE BEEN

6844
04:14:51,894 --> 04:14:56,398
WORKING TOWARDS FOR SOMETIME.

6845
04:14:56,398 --> 04:14:58,467
SO ADVISORY COMMITTEE YOU ARE

6846
04:14:58,467 --> 04:15:00,169
IMPORTANT IN OUR EFFORTS AS YOU

6847
04:15:00,169 --> 04:15:01,337
MOVE FORWARD AND I WANTED TO

6848
04:15:01,337 --> 04:15:05,674
MAKE SURE YOU WERE AWARE OF THIS

6849
04:15:05,674 --> 04:15:08,611
EXCITING EVENTS AND THOSE

6850
04:15:08,611 --> 04:15:10,779
NUMBERS ARE NOW AVAILABLE WITH

6851
04:15:10,779 --> 04:15:12,414
THE RCDC WEBSITE AND LET ME JUST

6852
04:15:12,414 --> 04:15:14,016
PAUSE AND SEE IF THERE ARE

6853
04:15:14,016 --> 04:15:24,393
QUESTIONS OR COMMENTS.

6854
04:15:26,862 --> 04:15:30,099
OKAY, WE ARE GOING TO TAKE AN

6855
04:15:30,099 --> 04:15:31,267
EARLIER BREAK, WE WERE SUPPOSED

6856
04:15:31,267 --> 04:15:35,971
TO TAKE A BREAK FROM 2  2:15, WE

6857
04:15:35,971 --> 04:15:38,541
WILL TAKE A BREAK UNTIL 2:25 AND

6858
04:15:38,541 --> 04:15:41,243
WE WILL SEE YOU IN 10 OR 12

6859
04:15:41,243 --> 04:15:43,379
MINUTES. 

6860
04:15:43,379 --> 04:15:44,157
THANKS EVERYONE.

6861
04:15:44,157 --> 04:15:49,329
WELCOME BACK, EVERYBODY. 

6862
04:15:49,329 --> 04:15:52,132
HOME STRETCH.

6863
04:15:52,132 --> 04:15:54,100
PER THE FEDERAL ADVISORY

6864
04:15:54,100 --> 04:15:55,635
COMMITTEE ACT, OR FACA

6865
04:15:55,635 --> 04:15:58,037
REGULATIONS, ANY MEMBER OF THE

6866
04:15:58,037 --> 04:16:00,507
PUBLIC IS ALLOWED TO FILE A

6867
04:16:00,507 --> 04:16:02,142
LETTER AND STATEMENT IF

6868
04:16:02,142 --> 04:16:02,809
INTERESTED IN PRESENTING ORAL

6869
04:16:02,809 --> 04:16:04,043
COMMENT TO THE COMMITTEE AT THIS

6870
04:16:04,043 --> 04:16:06,146
TIME WE WANT TO ACKNOWLEDGE THE

6871
04:16:06,146 --> 04:16:08,148
WRITTEN COMMENTS RECEIVED BY THE

6872
04:16:08,148 --> 04:16:09,649
PHYSICIAN'S COMMITTEE FOR

6873
04:16:09,649 --> 04:16:10,450
RESPONSIBLE MEDICINE, AND OPEN

6874
04:16:10,450 --> 04:16:14,053
THE FLOOR FOR AN ORAL COMMENT

6875
04:16:14,053 --> 04:16:15,889
FROM THE AMERICAN GUIN

6876
04:16:15,889 --> 04:16:20,059
OICOLOGGIC SOCIETY WHICH WILL BE

6877
04:16:20,059 --> 04:16:24,898
PRESENTED BY DR. WINESTEIN,

6878
04:16:24,898 --> 04:16:26,866
CHIEF THE GYNECOLOGY AND PELVIC

6879
04:16:26,866 --> 04:16:28,935
SURGERY AND CO CHAIR OF THE

6880
04:16:28,935 --> 04:16:34,140
CENTER FOR PELVIC FLOOR DISORDER

6881
04:16:34,140 --> 04:16:35,742
AT MASS GENERAL HOSPITAL

6882
04:16:35,742 --> 04:16:38,144
ASSOCIATE PROFESSOR OF

6883
04:16:38,144 --> 04:16:38,978
OBSTETRICS AND PREPRODUCTIVE

6884
04:16:38,978 --> 04:16:43,149
BIOLOGY AT HARVARD MEDICAL

6885
04:16:43,149 --> 04:16:43,383
SCHOOL.

6886
04:16:43,383 --> 04:16:43,650
WELCOME.

6887
04:16:43,650 --> 04:16:44,584
THANK YOU SO MUCH IF ARE THIS

6888
04:16:44,584 --> 04:16:47,787
TIEWPT AND THANK YOU FOR THE

6889
04:16:47,787 --> 04:16:49,956
OPPORTUNITY TO PROPROVIDE

6890
04:16:49,956 --> 04:16:52,325
WRITTEN AND ALAL COMMENTS, I AM

6891
04:16:52,325 --> 04:16:53,293
WITH THE MASS GENERAL HOSPITAL

6892
04:16:53,293 --> 04:16:57,363
AND MY RESEARCH INTERESTS NEAR

6893
04:16:57,363 --> 04:16:59,532
COMBINED PELVIC FLOOR DISORDERS,

6894
04:16:59,532 --> 04:17:00,833
IMAGING AND PELVIC FLOOR

6895
04:17:00,833 --> 04:17:01,301
OUTCOMES.

6896
04:17:01,301 --> 04:17:04,804
TODAY I'M SPEAKING TO YOU IN A

6897
04:17:04,804 --> 04:17:07,674
ROLE AS A AMERICAN UROLOGICAL

6898
04:17:07,674 --> 04:17:09,375
SCIENTIFIC COMMITTEE.

6899
04:17:09,375 --> 04:17:12,378
AUGs, IT'S A NATIONAL MEDICAL

6900
04:17:12,378 --> 04:17:13,546
SOCIETY REPRESENTING OVER 2000

6901
04:17:13,546 --> 04:17:15,648
MEMBERS INCLUDING PRACTICING

6902
04:17:15,648 --> 04:17:16,683
PHYSICIANS NURSE PRACTITIONERS,

6903
04:17:16,683 --> 04:17:17,317
PHYSICAL THERAPY AND ACTIVITIES

6904
04:17:17,317 --> 04:17:18,084
AND PROJECTS IOF THEDS,

6905
04:17:18,084 --> 04:17:19,586
HEALTHCARE PROFESSIONALS AND

6906
04:17:19,586 --> 04:17:20,753
RESEARCHERS FROM MANY

6907
04:17:20,753 --> 04:17:23,556
DISCIPLINES DEDICATING TO TREATS

6908
04:17:23,556 --> 04:17:26,793
ANDING FEMALE PELVIC FLOOR

6909
04:17:26,793 --> 04:17:28,628
DISORDERS OR FFDs, WE WANT TO

6910
04:17:28,628 --> 04:17:31,030
UNDERSTAND THE IMPORTANCE OF

6911
04:17:31,030 --> 04:17:31,631
UNDERSTANDING AND EVALUATING

6912
04:17:31,631 --> 04:17:32,899
CONDITIONS WOMEN FACE THROUGHOUT

6913
04:17:32,899 --> 04:17:33,967
THEIR LIVES INCLUDING CONDITIONS

6914
04:17:33,967 --> 04:17:38,404
THAT BECOME MORE PREVALENT IN

6915
04:17:38,404 --> 04:17:39,272
POST REPRODUCTIVE YEARS.

6916
04:17:39,272 --> 04:17:41,274
IT'S NOTABLE THAT MOST FUNDING

6917
04:17:41,274 --> 04:17:48,348
DEVOTED TO HEALTH RESEARCH IS

6918
04:17:48,348 --> 04:17:49,916
FOCUSED ON REPRODUCTIVE AGE

6919
04:17:49,916 --> 04:17:50,883
SPANS INCLUDING THOSE THAT

6920
04:17:50,883 --> 04:17:52,352
WORSEN WITH THE MENOPAUSAL

6921
04:17:52,352 --> 04:17:54,621
CONDITION AND THOSE THAT

6922
04:17:54,621 --> 04:18:00,493
TRANSITION AND THOSE IN POST

6923
04:18:00,493 --> 04:18:02,695
PRODUCTION OF U.S. WOMEN.

6924
04:18:02,695 --> 04:18:04,831
AS SUCH AUG STRONGLY SUPPORTS

6925
04:18:04,831 --> 04:18:07,166
RESEARCH FUNDING DEDICATED TO

6926
04:18:07,166 --> 04:18:10,670
WHOLIC WOMEN'S HEALTH FOCUSING

6927
04:18:10,670 --> 04:18:15,575
ON STUDIES TO URO-GYNECOLOGIC

6928
04:18:15,575 --> 04:18:16,876
DISORDERS INCLUDING PFDs

6929
04:18:16,876 --> 04:18:19,979
AFFECT 25 MILLION INDIVIDUALS IN

6930
04:18:19,979 --> 04:18:21,481
NEARLY EVERY COMMON OLDER WOMEN

6931
04:18:21,481 --> 04:18:24,984
AND 1 IN 4 WOMEN WILL FACE

6932
04:18:24,984 --> 04:18:26,953
PELVIC FLOOR DISORDER IN THEIR

6933
04:18:26,953 --> 04:18:28,588
LIFETIME AND THE RATE IS LIKELY

6934
04:18:28,588 --> 04:18:34,460
HIGHER IN WOMEN OVER AGE 65.

6935
04:18:34,460 --> 04:18:35,995
SPFD IS DECREASED AFTER

6936
04:18:35,995 --> 04:18:40,133
MENOPAUSE, WE WILL SUFFER FROM

6937
04:18:40,133 --> 04:18:45,204
INCONTINENCE AND ONE-THIRD OF

6938
04:18:45,204 --> 04:18:48,174
WOMEN EXPERIENCE URINARY TRACT

6939
04:18:48,174 --> 04:18:49,609
INFECTIONS, MOST CONDITIONS STAY

6940
04:18:49,609 --> 04:18:53,813
FOR EXTENDED PERIODS OF TIME AND

6941
04:18:53,813 --> 04:18:55,281
REQUIRE ONGOING MEDICAL

6942
04:18:55,281 --> 04:18:56,416
CONDITION.

6943
04:18:56,416 --> 04:18:59,986
IN TWE 23, AUG RELEASED

6944
04:18:59,986 --> 04:19:02,955
INFORMATION FOR THE PUBLIC

6945
04:19:02,955 --> 04:19:04,090
DISORDERS, RCHT IDENTIFY

6946
04:19:04,090 --> 04:19:05,892
KNOWLEDGE GAPS IN RESEARCH

6947
04:19:05,892 --> 04:19:08,795
RIPORRITYS ACROSS 6 SPECIFIC

6948
04:19:08,795 --> 04:19:12,899
TOPICS, LOWER URINARY TRACT

6949
04:19:12,899 --> 04:19:14,634
SYMPTOMS, FECAL INCONTINENCE,

6950
04:19:14,634 --> 04:19:17,236
URINARY TRACT INFECTIONS, SEXUAL

6951
04:19:17,236 --> 04:19:21,074
DISTUNKZ IN WOMEN WITH PELVIC

6952
04:19:21,074 --> 04:19:26,279
DISORDERS AND MY O FACIAL SYSTEM

6953
04:19:26,279 --> 04:19:27,146
CONDITION AND MORE.

6954
04:19:27,146 --> 04:19:29,582
WITH THE TIME PERMITTING I WILL

6955
04:19:29,582 --> 04:19:33,019
FOCUS ON ON ONLY 1 OF 2 OF THIS

6956
04:19:33,019 --> 04:19:34,821
CONDITION, PELVIC ORGAN PROLAPSE

6957
04:19:34,821 --> 04:19:38,024
IS THE DESCENT OF 1 OF THE

6958
04:19:38,024 --> 04:19:39,726
PELVIC ORGANS INTO OR OUTSIDE OF

6959
04:19:39,726 --> 04:19:41,027
THE VARMIS BEGINNA AND IT

6960
04:19:41,027 --> 04:19:43,629
AFFECTS UP TO 50% OF ALL WOMEN.

6961
04:19:43,629 --> 04:19:46,466
THIS CONDITION CAN SEVERELY

6962
04:19:46,466 --> 04:19:48,534
IMPACT QUALITY OF LIFE PROMPTING

6963
04:19:48,534 --> 04:19:52,138
WOMEN IN THE UNITED STATES TO

6964
04:19:52,138 --> 04:19:53,439
UNDERGO SURGICAL PROLAPSE,

6965
04:19:53,439 --> 04:19:56,042
WORSENING PROLAPSE HAS BEEN

6966
04:19:56,042 --> 04:19:57,877
ASSOCIATED WITH FUNCTION,

6967
04:19:57,877 --> 04:19:59,746
ANXIOUS, DEPRESSION, SLEEP

6968
04:19:59,746 --> 04:20:00,780
DISTORTIONS AND LOWER

6969
04:20:00,780 --> 04:20:01,748
SATISFACTION PARTICIPATING IN

6970
04:20:01,748 --> 04:20:04,217
SOCIAL ROLES, OVERALL THE

6971
04:20:04,217 --> 04:20:04,884
PATHOPHYSIOLOGIC MECHANISM

6972
04:20:04,884 --> 04:20:06,419
UNDERLYING THIS DEVELOPMENT OF

6973
04:20:06,419 --> 04:20:08,688
PROGRESSION OF SEVERITY OF

6974
04:20:08,688 --> 04:20:09,822
PROLAPSE ARE MEDICALLY

6975
04:20:09,822 --> 04:20:13,126
UNDERSTOOD AND NO EFFECT

6976
04:20:13,126 --> 04:20:14,160
PREVENTATIVE STRATEGIES EXIST

6977
04:20:14,160 --> 04:20:15,895
AGAINST PROLAPSE IN CURRENT

6978
04:20:15,895 --> 04:20:18,398
TREATMENT MODALITIES ARE DELAYED

6979
04:20:18,398 --> 04:20:19,766
AND COMP PENSATORY.

6980
04:20:19,766 --> 04:20:21,768
IDENTIFYING THEMES THAT WE WANT

6981
04:20:21,768 --> 04:20:26,439
TO EXPLORE ARE NORMAL FUNCTIONAL

6982
04:20:26,439 --> 04:20:29,609
ANATOMY, CELLULAR GENETICS AND

6983
04:20:29,609 --> 04:20:31,077
BIOMECHANICAL FACTORS, THERAPIES

6984
04:20:31,077 --> 04:20:32,712
FOR PREVENTION TREATMENT AND

6985
04:20:32,712 --> 04:20:33,980
RECURRENCE, SOCIETAL IMPACT AND

6986
04:20:33,980 --> 04:20:36,983
FINANCIAL BURDEN ON TREATMENT OF

6987
04:20:36,983 --> 04:20:38,851
THIS MODALITIES, AH, G STRONGLY

6988
04:20:38,851 --> 04:20:39,886
SUPPORTS THE INCREASED RESEARCH

6989
04:20:39,886 --> 04:20:41,220
FUNDING ON THESE RESEARCH TOPIC

6990
04:20:41,220 --> 04:20:42,822
AREAS THAT ARE IN ADDRESS

6991
04:20:42,822 --> 04:20:44,991
RESEARCH GAPS AND INVEST IN THE

6992
04:20:44,991 --> 04:20:46,526
FULL FEMALE LIFE SPANS AND

6993
04:20:46,526 --> 04:20:49,362
IMPROVED CARE OF DELIVERY OF

6994
04:20:49,362 --> 04:20:50,096
PFDs IN CONDITION ANDS THANK

6995
04:20:50,096 --> 04:20:51,664
YOU VERY MUCH FOR YOUR WORK ON

6996
04:20:51,664 --> 04:20:53,366
WOMEN'S HEALTH RESEARCH FUNDING

6997
04:20:53,366 --> 04:20:57,170
AND FOR THEIR OPPORTUNITY TO PUT

6998
04:20:57,170 --> 04:21:04,377
THEM IN THE PUBLIC COMMENTS.

6999
04:21:04,377 --> 04:21:09,282
>> OKAY, THANK YOU ONCE
MORE

7000
04:21:09,282 --> 04:21:10,149
DR. WINESTEIN, APPRECIATE YOUR

7001
04:21:10,149 --> 04:21:10,416
COMMENTS.

7002
04:21:10,416 --> 04:21:13,519
BEFORE WE CLOSE I WOULD LIKE TO

7003
04:21:13,519 --> 04:21:15,354
ASK, INVITE DR. OTA WANG TO

7004
04:21:15,354 --> 04:21:16,989
RESPOND TO ANY QUESTIONS SENT

7005
04:21:16,989 --> 04:21:21,327
FROM THE PUBLIC SENT TO THE

7006
04:21:21,327 --> 04:21:21,594
WRCHINBOX?

7007
04:21:21,594 --> 04:21:24,197
TLOOKS LIKE WE DON'T HAVE ANY

7008
04:21:24,197 --> 04:21:27,233
QUESTIONS SUBCOMMITTED COMMITTE-

7009
04:21:27,233 --> 04:21:28,434
SUBMITTED BUT IF THERE ARE

7010
04:21:28,434 --> 04:21:29,435
QUESTIONS AFTERWARDS WE WILL BE

7011
04:21:29,435 --> 04:21:31,904
MORE THAN HAPPY TO WORRY THEM.

7012
04:21:31,904 --> 04:21:36,742
SO WHAT I WILL NOW DO IS TURN IT

7013
04:21:36,742 --> 04:21:39,479
OVER TO DR. CLAYTON.

7014
04:21:39,479 --> 04:21:42,548
>> THANK YOU DR. OTA WANG.

7015
04:21:42,548 --> 04:21:45,551
FIRST I WANT TO THANK ALL OF THE

7016
04:21:45,551 --> 04:21:47,086
EXCELLENT PRESENTERS FOR

7017
04:21:47,086 --> 04:21:47,820
PARTICIPATING IN TODAY'S

7018
04:21:47,820 --> 04:21:49,789
ADVISORY COMMITTEE FOR RESEARCH

7019
04:21:49,789 --> 04:21:52,058
ON WOMEN'S HEALTH MEETING, WE

7020
04:21:52,058 --> 04:21:53,459
DEEPLY APPRECIATE THE CONTINUED

7021
04:21:53,459 --> 04:21:56,762
SUPPORT THAT THE ACRW H AS WELL

7022
04:21:56,762 --> 04:21:57,964
MEMBERS, PROVIDE TO OUR OFFICE

7023
04:21:57,964 --> 04:22:00,132
AND I WOULD LOAMACYIC TO ALSO

7024
04:22:00,132 --> 04:22:02,101
THANK THE OFFICE OF RESEARCH ON

7025
04:22:02,101 --> 04:22:03,736
WOMEN'S HEALTH, FEDERAL STAFF

7026
04:22:03,736 --> 04:22:05,271
AND OUR CONTRACTORS SUPPORT FOR

7027
04:22:05,271 --> 04:22:08,508
MAKING THIS MEETING POSSIBLE.

7028
04:22:08,508 --> 04:22:10,843
ON BEHALF OF ORWH, I THANK ALL

7029
04:22:10,843 --> 04:22:11,944
OF YOU AND LOOK FORWARD TO

7030
04:22:11,944 --> 04:22:14,013
SEEING YOU AT THE 64th MEETING

7031
04:22:14,013 --> 04:22:15,982
OF THE ADVISORY COMMITTEE ON

7032
04:22:15,982 --> 04:22:18,217
RESEARCH ON WOMEN'S HEALTH ON

7033
04:22:18,217 --> 04:22:20,720
OCTOBER 7th, 2025, WHICH WILL

7034
04:22:20,720 --> 04:22:21,888
BE AN IN-PERSON MEETING.

7035
04:22:21,888 --> 04:22:25,825
I HOPE YOU ALL REMAIN SAFE AND

7036
04:22:25,825 --> 04:22:27,560
HEALTHY AND TODAY'S MEETING IS

7037
04:22:27,560 --> 04:22:28,060
NOW ADJOURNED.

7038
04:22:28,060 --> 04:22:29,529
THANK YOU VERY MUCH.

7039
04:22:29,529 --> 04:22:29,795
EVERYONE.

7040
04:22:29,795 --> 04:22:39,795
APPRECIATE YOU BEING HERE.