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Mechanisms of breast cancer metastasis and targeting opportunities

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Air date: Friday, May 18, 2018, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 189, (62 Live, 127 On-demand)
Category: NIH Director's Seminars
Runtime: 00:50:52
Description: Director's Seminar Series

Cancer metastasis is the primary cause of cancer-associated death. Current treatment strategies have been largely ineffective in patients with metastatic disease. It’s becoming clear that the tumor microenvironment plays an essential role in the metastatic process. We investigate the critical inflammatory and immune suppressive mediators that promote metastatic cancer cell survival and colonization at distant organ site. Our work provides insights for metastatic biology and therapeutic options aimed at targeting metastatic breast cancer.
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NLM Title: Mechanisms of breast cancer metastasis and targeting opportunities / Li Yang.
Author: Yang, Li.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): Director's Seminar Series Cancer metastasis is the primary cause of cancer-associated death. Current treatment strategies have been largely ineffective in patients with metastatic disease. It's becoming clear that the tumor microenvironment plays an essential role in the metastatic process. We investigate the critical inflammatory and immune suppressive mediators that promote metastatic cancer cell survival and colonization at distant organ site. Our work provides insights for metastatic biology and therapeutic options aimed at targeting metastatic breast cancer.
Subjects: Antineoplastic Agents--therapeutic use
Breast Neoplasms--drug therapy
Immunotherapy
Molecular Targeted Therapy
Neoplasm Metastasis--prevention & control
Tumor Microenvironment--drug effects
Publication Types: Lecture
Webcasts
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NLM Classification: WP 870
NLM ID: 101728504
CIT Live ID: 27841
Permanent link: https://videocast.nih.gov/launch.asp?23892