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Gut reactions: host microbiome interactions in the intestine in health and disease

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Air date: Wednesday, March 14, 2018, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 607, (357 Live, 250 On-demand)
Category: WALS - Wednesday Afternoon Lectures
Runtime: 01:00:44
Description: NIH Director's Wednesday Afternoon Lecture Series

The gastrointestinal tract is home to a large number and vast array of bacteria that play an important role in nutrition, immune-system development, and host defense. In inflammatory bowel disease there is a breakdown in this mutualistic relationship resulting in aberrant inflammatory responses to intestinal bacteria. Studies in model systems indicate that intestinal homeostasis is an active process involving a delicate balance between effector and immune suppressive pathways. For her presentation, Dr. Powrie will discuss bacterial pathways that promote intestinal homeostasis and host defense, and how these may be harnessed therapeutically.

For more information go to https://oir.nih.gov/wals/2017-2018/
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NLM Title: Gut reactions : host microbiome interactions in the intestine in health and disease / Fiona Powrie.
Author: Powrie, Fiona.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): NIH Director's Wednesday Afternoon Lecture Series The gastrointestinal tract is home to a large number and vast array of bacteria that play an important role in nutrition, immune-system development, and host defense. In inflammatory bowel disease there is a breakdown in this mutualistic relationship resulting in aberrant inflammatory responses to intestinal bacteria. Studies in model systems indicate that intestinal homeostasis is an active process involving a delicate balance between effector and immune suppressive pathways. For her presentation, Dr. Powrie will discuss bacterial pathways that promote intestinal homeostasis and host defense, and how these may be harnessed therapeutically.
Subjects: Gastrointestinal Microbiome--immunology
Homeostasis--immunology
Host-Pathogen Interactions--immunology
Inflammatory Bowel Diseases--immunology
Microbial Interactions--immunology
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: WI 420
NLM ID: 101724471
CIT Live ID: 27199
Permanent link: https://videocast.nih.gov/launch.asp?23754