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Vesicular transmission of viral populations: strength in numbers (HHS Only)

Air date: Friday, February 23, 2018, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Description: Director's Seminar Series

Using interdisciplinary approaches from cell biology to virology to immunology, we investigate the strategies exploited by viruses to successfully transmit themselves among hosts. We recently discovered a novel form of viral transmission in which viruses are transmitted among hosts, not as single infectious units, but as populations of infectious units clustered inside vesicles. We have found this type of en masse transmission to be widespread in nature, taking place both within as well as between hosts and notably leading to enhanced viral infectivity, suppression of host immune responses and thereby greater virulence.
Author: Nihal Altan-Bonnet, Ph.D., Senior Investigator, Head of Laboratory of Host-Pathogen Dynamics, NHLBI, NIH
Runtime: 1 hour