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Autotherapies are treatments based on the body’s natural ability to heal and protect itself. For example, immunotherapy harnesses the body’s immune cells to fight cancer and is now in clinical use. In the dental, oral, and craniofacial region, autotherapies could be used to selectively signal the body to repair and regenerate tissue, trigger immune responses, and restore a natural microbial balance. These strategies might also help to heal damaged or diseased tissues in other parts of the body, prevent or treat infections, fight cancer, treat autoimmune conditions, and enhance overall health.
Advancing the development of autotherapies is one of the five goals of NIDCR 2030 external link–NIDCR’s vision for the future of dental, oral, and craniofacial re