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Principles of Epigenetics and Chromatin in Development and Human Disease (HHS Only)

Air date: Friday, October 27, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Description: NCI’s Center for Cancer Research (CCR) Grand Rounds

Dr. Ali Shilatifard, Professor and Chairman of the Department of Biochemistry and Molecular Genetics of the Northwestern University Feinberg School of Medicine, is a world renown biochemist and molecular biologist. He is a respected expert in the field of transcription and epigenetics, specifically as it relates to cancer biology. He has an immense interest in understanding the intricate molecular mechanisms of the regulation of gene expression, the mechanisms that activate or suppress a particular gene’s traits. As a Jane Coffin Childs postdoctoral fellow, Dr. Shilatifard made a seminal contribution to the field of leukemia biology by identifying the first function of any of the MLL translocation partners, which is when a section of one chromosome changes place with that of another chromosome creating a mutation. Since then, he has continued to contribute to the field of transcription, chromatin biology, and cancer biology through many discoveries including those of the COMPASS and SEC complexes, which are proving to be central to the mechanisms involved in the development of leukemia and other cancers.

Dr. Shilatifard has been recognized by the Leukemia and Lymphoma Society, is a recipient of the Sword of Hope from the American Cancer Society, and received the American Society of Biochemistry and Molecular Biology Amgen Award. He has been funded through three major grants from the National Institutes of Health, and National Cancer Institute (NCI). Dr. Shilatifard was selected as an inaugural recipient of the NCI Outstanding Investigator Award Institute and in 2016 he received the Walder Research Award from Northwestern University. He serves as a Senior Editor for the journal Science, a Deputy Editor for Science Advances, Editor for Molecular and Cellular Biology, and also serves on the Scientific Advisory Boards of Genentech and the Max Planck Society.
Author: Ali Shilatifard, Ph.D., Robert Francis Furchgott Professor; Chairman, Department of Biochemistry and Molecular Genetics; Professor of Pediatrics; Northwestern University Feinberg School of Medicine
Runtime: 1 hour