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CANCELLED - RNA splice codes for synapse specification and neuronal plasticity

   
Air date: Monday, December 11, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Description: Please note the NIH Neuroscience Series lecture on Monday, December 11, 2017 at noon in the Porter Neuroscience Research Center, Room 620, Building 35, has been cancelled due to bad weather and flight cancellation.

NIH Neuroscience Series Seminar

The brain is one of the most fascinating and complex systems in the body. It controls sensory perceptions, emotions, and actions and makes it possible to form memories and learn highly specialized behaviors. Changes in the connectivity and function of neurons underlie disorders such as autism and schizophrenia, which pose significant challenges to today's society. The aim of Dr. Scheiffele lab’s research is to understand the mechanisms in the formation of neuronal networks in the central nervous system. They are therefore primarily investigating the cellular interactions and molecular signals that regulate neuronal connectivity during embryonic and postnatal development of the brain.

They are focusing on the study of synapses, the information interfaces of neuronal networks. They are seeking to understand how synapses are formed, in particular how neurons recognize the correct synaptic partners and initiate neuronal links with them, and how inappropriate connections are eliminated. They apply a broad range of molecular, anatomic, and electrophysiological methods that allow them to analyze the specificity and function of neuronal synapses in the intact brain tissue of transgenic mice and in cultured cells. Their experimental models for mechanisms of neuronal network formation serve not only the aims of basic research but also provide insights into functional changes that occur in disease. They analyze the neuronal consequences of risk factors for autism and apply their models to test therapeutic strategies..

For more information go to https://neuroscience.nih.gov/neuroseries/Home.aspx
Author: Peter Scheiffele, Ph.D., University of Basel
Runtime: 1 hour