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Sensory Molecules and Mechanisms in Worms

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Air date: Monday, October 16, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 53, (22 Live, 31 On-demand)
Category: Neuroscience
Runtime: 01:08:18
Description: NIH Neuroscience Series Seminar

The fundamental nature of mental phenomena such as perception, learning and memory is one of the remaining scientific mysteries. Since the neuroanatomy of mammalian nervous systems is exceedingly complex and incompletely characterized, it is difficult to understand mechanistically how the human brain works at the level of molecules and cells. However, in simpler organisms like the nematode C. elegans, obtaining a reductionist understanding of nervous system function and behaviour is a tractable problem.

Aspects of nervous system function in which Dr. Schafer’s lab is investigating in C. elegans include mechanosensation: how do neurons sense stimuli such as touch and pain, and how do sensory circuits integrate and process this information. They are also interested in behavioural states: how do contextual cues such as satiety and the presence of food influence behaviour through defined neural circuits, and what roles do molecules like dopamine, serotonin and neuropeptides play in these processes.

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Author: William Schafer, Ph.D., University of Cambridge
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CIT Live ID: 24837
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