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CANCELLED - Cellular EcologyHHS Only

Air date: Wednesday, October 25, 2017, 4:15:00 PM
Time displayed is Eastern Time, Washington DC Local
Description: IIG seminar All untransformed cells require specific growth factors for survival and proliferation. Local provision of growth factors determines tissue composition and size. However, the rules that govern growth factor production are largely unknown. Consequently, we do not know how these rules are violated to produce specific patterns of tissue pathology. In this lecture I will discuss our recent study addressing these questions. Using simplified two cell circuit system, we find that certain features of cell circuit topologies enable generation of stable cell composition. These findings will be discussed in a broader context of tissue homeostasis and disease.
Author: Ruslan Medzhitov, Ph.D., professor of Immunobiology, Yale School of Medicine
Runtime: 1 hour, 15 minutes