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Dr. Clark attended Caltech as an undergraduate, where she was told to avoid a career in medicine. Despite this excellent advice, she completed the M.D./Ph.D. program at Harvard Medical School and now serves as the Shing-Yiu Yip and Cecilia M. Hepp Associate Professor of Dermatology at Harvard Medical School and the Director of the NIAMS P30 funded Human Skin Disease Resource Center. Her research focuses on the study of human T cell responses in skin and other peripheral tissues, including T cell function in healthy skin, impaired T cell migration and responses in skin cancer, and maladaptive T cell activation in inflammatory skin diseases and cutaneous lymphomas. Her studies, driven by observations in patients and carried out on human tissues, have the goals of developing novel therapies for skin disease and advancing our understanding of human immune responses.