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Monocyte Heterogeneity: Implications for Cancer

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Air date: Wednesday, November 29, 2017, 4:15:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 213, (49 Live, 164 On-demand)
Category: Immunology
Runtime: 00:54:37
Description: Immunonology IG Seminar

Monocytes are key cells that drive the rapid innate immune response. We discovered that a subset of monocytes, nonclassical monocytes (CD14dim in humans and Ly6C- in mice), function in the vasculature to recognize metastasizing tumor cells. Once these cells recognize tumor cells, they orchestrate the killing of these cells to prevent metastasis. This presentation will discuss how nonclassical monocytes regulate tumor cell killing, and will discuss the possible use of nonclassical monocytes in cancer immunotherapy.
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Author: Catherine “Lynn” Hedrick, Ph.D., Professor, Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology
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CIT Live ID: 23471
Permanent link: https://videocast.nih.gov/launch.asp?23608