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Dr. Jonathan Lyons received his undergraduate education from Pomona College, and a Doctorate of Medicine from the University of Southern California in 2007. Dr. Lyons completed residency training in Internal Medicine at the University of California, San Diego, in 2010, remaining an additional year as a Chief Medical Resident. He concluded his formal medical training as a clinical fellow in Allergy and Immunology at NIAID in 2014. Following completion of fellowship, Jonathan was selected for the NIAID Transition Program in Clinical Research, and he is currently an Assistant Clinical Investigator in the Laboratory of Allergic Diseases. He has been a member of the Genetics and Pathogenesis of Allergy Section since 2012. During that time, he has contributed to the identification of a number of novel monogenic causes of allergic inflammation and immune dysregulation. His current areas of research build upon two of the major findings of his previous work: 1) characterizing mechanisms by which metabolic derangement can promote allergic disease; and 2) studying individuals with hereditary alpha tryptasemia in order to elucidate pathways that promote myeloid proliferation and mast cell reactivity, which can ultimately be targeted to limit anaphylaxis and treat myeloproliferative disease
Jonathan Lyons, MD, Assistant Clinical Investigator, Genetics and Pathogenesis of Allergy Section, NIAID, NIH