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Neuron-Glia Interactions: Their Mechanisms and Their Roles in Development and Disease

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Air date: Monday, September 10, 2007, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 215 * This only includes stats from October 2011 and forward.
Category: Neuroscience
Runtime: 00:50:03
Description: Dr. Corfas is interested in understanding the molecular signals that regulate neuron-glia interactions, which play critical roles in several aspects of nervous-system development, including neuronal migration, neuronal and glial differentiation and survival, and the formation and function of synapses. To this end, his research employs molecular and cellular biological techniques, as well as genetically modified mice.

One aspect of Dr. Corfas' work focuses on the growth factor neuregulin (NRG) and its erbB receptors, key mediators of neuron-glia interactions. He and his colleagues have found that these molecules mediate interactions between migrating neurons and the radial glial fibers along which they migrate during the development of the central nervous system, and between several types of glia and neurons in the adult nervous system.

NIH Neuroscience Seminar Series
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NLM Title: Neuron-glia interactions : their mechanisms and their roles in development and disease / Gabriel Corfas.
Author: Corfas, Gabriel.
National Institutes of Health (U.S.)
Publisher:
Abstract: (CIT): Dr. Corfas is interested in understanding the molecular signals that regulate neuron-glia interactions, which play critical roles in several aspects of nervous-system development, including neuronal migration, neuronal and glial differentiation and survival, and the formation and function of synapses. To this end, his research employs molecular and cellular biological techniques, as well as genetically modified mice. One aspect of Dr. Corfas' work focuses on the growth factor neuregulin (NRG) and its erbB receptors, key mediators of neuron-glia interactions. He and his colleagues have found that these molecules mediate interactions between migrating neurons and the radial glial fibers along which they migrate during the development of the central nervous system, and between several types of glia and neurons in the adult nervous system.
Subjects: Nervous System Physiological Phenomena
Neuroglia--physiology
Publication Types: Lecture
Webcast
Download: To download this event, select one of the available bitrates:
[384k]    How to download a Videocast
NLM Classification: WL 102
NLM ID: 101317970
CIT Live ID: 6161
Permanent link: https://videocast.nih.gov/watch=6161