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The course includes presentation of patients, pathology, diagnosis and therapy in the context of major disease problems and current research. Primarily directed toward Ph.D. students, fellows, and staff, it is also of interest to medical students and clinicians. The course is designed to help bridge the gap between advances in biology and their application to major human diseases. Each session includes clinical and basic science components which are presented by NIH staff and outside invitees.
Demystifying medicine. Malaria : the number one killer / Rick Fairhurst and Tom Wellems.
Fairhurst, Rick. National Institutes of Health (U.S.)
Part of the Demystifying Medicine series at the National Institutes of Health (NIH), this lecture by Thomas E. Wellems and Rick M. Fairhurst of the National Institute of Allergy and Infectious Diseases (NIAID) examines the worldwide history of malaria, its current prevalence, cause, and treatments, those factors which confer resistance or immunity in humans, and the rise of chloroquine-resistant strains of malaria. A case study of a 30-year-old American male who contracted malaria after travel to Africa and South America is presented. The still-high death rate in parts of Africa in children under five is discussed, as are genetic factors that help determine the severity of the illness. Lecturers note that the sickle trait confers resistance and is common in African populations, but absent in Southeast Asia.