||The overall aim of the research in Dr. Ashcroft's laboratory is to understand how glucose stimulates insulin secretion from the beta-cells of the pancreatic islets, what goes wrong with this process in type 2 (adult-onset) diabetes and how the sulphonylurea drugs used to treat type-2 diabetes exert their beneficial effects. Central to all these aims is the ATP-sensitive potassium (K-ATP) channel, which plays a key role in the physiology and pathophysiology of the beta-cell.
The NIH Neuroscience Seminar Series features lectures and discussions with leading neuroscientists. Sponsored by NINDS, NIMH, NIDCD, NIDA, NICHD, NEI, NIAAA and NIDCR, this year's series offers advances that span the areas of molecular, cellular and developmental neuroscience as well as cognitive sciences and neuroscience related topics in pain and other diseases.
NIH Neuroscience Seminar Series