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Cortical Microcircuits and Maps: Structure and Function
Tuesday, January 24, 2006,
12:00:00 PM Time displayed is Eastern Time, Washington DC Local
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Dr. Sakmann’s lab aims to elucidate mechanisms of fast signalling within nerve cells, between nerve cells and of long-term changes in their synaptic coupling. Nerve cells are highly polarized cells with different compartments referred to as dendrites, soma, axon and terminals. Electrical signals also are used to communicate between these compartments. Electrical signals are encoded as a transient rise in intracellular calcium. To decipher this code and identify the intracellular receivers of calcium transients is one of their aims. Nerve cells communicate with each other via synapses and the elucidation of transmitter release and its postsynaptic action in CNS synapses is the second main theme.