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Uncovering Unknown Unknowns of Gene Regulation

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Air date: Friday, April 13, 2018, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 269, (138 Live, 131 On-demand)
Category: NIH Director's Seminars
Runtime: 00:57:23
Description: NIH Director's Seminar Series

Identification of genes and processes associated with specific biological phenotypes is a fundamental step toward understanding the molecular basis of development and pathogenesis. This seminar will discuss the use of integrative systems biology approaches to uncover unknown unknowns of gene regulation. Dr. Raja Jothi will discuss data-driven efforts toward identification and characterization of genes with previously unknown roles in embryonic stem cell biology and findings on an unanticipated role for intragenic enhancers in attenuating their host gene expression.
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NLM Title: Uncovering unknown unknowns of gene regulation / Raja Jothi.
Author: Jothi, Raja.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): NIH Director's Seminar Series Identification of genes and processes associated with specific biological phenotypes is a fundamental step toward understanding the molecular basis of development and pathogenesis. This seminar will discuss the use of integrative systems biology approaches to uncover unknown unknowns of gene regulation. Dr. Raja Jothi will discuss data-driven efforts toward identification and characterization of genes with previously unknown roles in embryonic stem cell biology and findings on an unanticipated role for intragenic enhancers in attenuating their host gene expression.
Subjects: Embryonic Stem Cells
Enhancer Elements, Genetic
Gene Expression Regulation
Publication Types: Lecture
Webcasts
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Caption Text: Download Caption File
NLM Classification: QU 475
NLM ID: 101726631
CIT Live ID: 27465
Permanent link: https://videocast.nih.gov/launch.asp?23820