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Mechanisms of Synapse Formation and Axon Regeneration

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Air date: Monday, June 5, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 285, (43 Live, 242 On-demand)
Category: Neuroscience
Runtime: 01:01:41
Description: NIH Neuroscience Series Seminar

The Jin lab research focuses on the molecular genetic mechanisms underlying the development and function of the nervous system using the nematode Caenorhabditis elegans. The transparency, defined anatomy, and rapid life cycle of this organism greatly facilitate their studies at the subcellular resolution. Moreover, the entre cell lineage and connectome are known, enabling functional understanding at deep levels. Through forward genetic screening in combination with multi-layered molecular and cellular manipulations, they are discovering key molecules that play conserved roles in synapse formation, maintenance, and function, as well as those underlying adult axon regeneration. Their goal is to connect the studies of basic mechanisms to the understanding of human neurological disorders and neuronal repair.

For more information go to https://neuroscience.nih.gov/neuroseries/Home.aspx
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NLM Title: Mechanisms of synapse formation and axon regeneration / Yishi Jin.
Author: Jin, Yishi.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): NIH Neuroscience Series Seminar The Jin lab research focuses on the molecular genetic mechanisms underlying the development and function of the nervous system using the nematode Caenorhabditis elegans. The transparency, defined anatomy, and rapid life cycle of this organism greatly facilitate their studies at the subcellular resolution. Moreover, the entre cell lineage and connectome are known, enabling functional understanding at deep levels. Through forward genetic screening in combination with multi-layered molecular and cellular manipulations, they are discovering key molecules that play conserved roles in synapse formation, maintenance, and function, as well as those underlying adult axon regeneration. Their goal is to connect the studies of basic mechanisms to the understanding of human neurological disorders and neuronal repair.
Subjects: Axons--physiology
Caenorhabditis elegans--physiology
Electrical Synapses--physiology
Nerve Regeneration
Publication Types: Lecture
Webcasts
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Caption Text: Download Caption File
NLM Classification: WL 102.5
NLM ID: 101708385
CIT Live ID: 20274
Permanent link: https://videocast.nih.gov/launch.asp?23332