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Addressing Challenges in the Assessment of Botanical Dietary Supplement Safety (Day 1)

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Air date: Tuesday, April 26, 2016, 9:00:00 AM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 359, (166 Live, 193 On-demand)
Category: Conferences
Runtime: 06:13:39
Description: The safety of botanical dietary supplements, hereafter referred to as botanicals, is an important public health issue. According to the 2012 National Health Interview Survey, 17.7 percent of Americans reported having used nonvitamin, nonmineral dietary supplements (including botanicals) in the past 12 months (Clarke et al., 2015). Botanicals pose several unique challenges to efficacy and safety evaluation because of their inherent complexity and potential for wide variability in nominally related products. The interrelated challenges associated with the evaluation of botanicals include: (1) developing methods and criteria for assessing phytoequivalence (i.e., similarity in chemical composition and biological activity) of botanicals, (2) identifying the active constituent(s) or patterns of biological response of botanicals, and (3) assessing absorption, distribution, metabolism, and elimination (ADME) of botanicals. This workshop will engage experts from multiple disciplines to focus on practical approaches for addressing these challenges. Reference: Clarke, T.C. et al. Trends in the use of complementary health approaches among adults: United States, 2002-2012, in National health statistics reports. 2015. National Center for Heath Statistics: Hyattsville, MD.

For more information go to http://ntp.niehs.nih.gov/go/workshop_botanicals
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NLM Title: Addressing Challenges in the Assessment of Botanical Dietary Supplement Safety / National Institute of Environmental Health Sciences, NIH.
Author: Addressing Challenges in the Assessment of Botanical Dietary Supplement Safety (Workshop)
National Institute of Environmental Health Sciences,
Publisher:
Abstract: (CIT): The safety of botanical dietary supplements, hereafter referred to as botanicals, is an important public health issue. According to the 2012 National Health Interview Survey, 17.7 percent of Americans reported having used nonvitamin, nonmineral dietary supplements (including botanicals) in the past 12 months (Clarke et al., 2015). Botanicals pose several unique challenges to efficacy and safety evaluation because of their inherent complexity and potential for wide variability in nominally related products. The interrelated challenges associated with the evaluation of botanicals include: (1) developing methods and criteria for assessing phytoequivalence (i.e., similarity in chemical composition and biological activity) of botanicals, (2) identifying the active constituent(s) or patterns of biological response of botanicals, and (3) assessing absorption, distribution, metabolism, and elimination (ADME) of botanicals. This workshop will engage experts from multiple disciplines to focus on practical approaches for addressing these challenges. Reference: Clarke, T.C. et al. Trends in the use of complementary health approaches among adults: United States, 2002-2012, in National health statistics reports. 2015. National Center for Heath Statistics: Hyattsville, MD.
Subjects: Dietary Supplements--toxicity
Publication Types: Congress
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NLM Classification: QU 145.5
NLM ID: 101682337
CIT Live ID: 18163
Permanent link: https://videocast.nih.gov/launch.asp?19652