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Redox Biology 2014 - Introduction, Redox Chemistry

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Air date: Tuesday, September 23, 2014, 4:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 191, (17 Live, 174 On-demand)
Category: Redox Biology
Runtime: 01:51:54
Description: Redox Biology

Recent advances in the biochemistry of redox-active species and radicals are beginning to be translated into improvements in prevention and treatment of cancer. Traditionally, reactive species such as superoxide, hydrogen peroxide and nitric oxide (NO) are associated with toxicity; however, NO is useful in the treatment of angina and cardiovascular disease. Also, NO is involved in cancer tumor angiogenesis and apoptosis of cancer cells. This course is an overview presenting how redox-active species and radicals are generated; their effects on the cellular and physiological level, how they alter carcinogenesis, angiogenesis and proliferation in animal models of cancer, and how NO alters patient imaging profiles and response to cancer therapy. It consists of two 1-hour lectures with ample time for discussion and analysis. The participation of postdoctoral and clinical fellows interested in redox biology is encouraged.

For more information go to http://ccr.cancer.gov/careers/courses/rb
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NLM Title: Redox biology 2014. Introduction, redox chemistry / Terry Moody, David Wink.
Author: Moody, Terry W.
Wink, David A.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): Recent advances in the biochemistry of redox-active species and radicals are beginning to be translated into improvements in prevention and treatment of cancer. Traditionally, reactive species such as superoxide, hydrogen peroxide and nitric oxide (NO) are associated with toxicity; however, NO is useful in the treatment of angina and cardiovascular disease. Also, NO is involved in cancer tumor angiogenesis and apoptosis of cancer cells. This course is an overview presenting how redox-active species and radicals are generated; their effects on the cellular and physiological level, how they alter carcinogenesis, angiogenesis and proliferation in animal models of cancer, and how NO alters patient imaging profiles and response to cancer therapy. It consists of two 1-hour lectures with ample time for discussion and analysis. The participation of postdoctoral and clinical fellows interested in redox biology is encouraged.
Subjects: Free Radicals--metabolism
Neoplasms--physiopathology
Oxidation-Reduction
Publication Types: Lecture
Webcasts
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NLM Classification: QU 125
NLM ID: 101642837
CIT Live ID: 14600
Permanent link: https://videocast.nih.gov/launch.asp?18634