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Molecular Dissection of Cannabis Sensitivity in the Developing Brain

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Air date: Monday, April 29, 2013, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 233, (21 Live, 212 On-demand)
Category: Neuroscience
Runtime: 01:02:22
Description: Neuroscience Seminar Series

The Harkany lab focuses on understanding the developmental organization and functions of the endocannabinoid system by using a combination of molecular genetics, neuroimaging, neuroanatomy and electrophysiology approaches. Besides focusing on physiological developmental programs controlled by endocannabinoid signaling during corticogenesis, substantial resources are dedicated to elucidating the neuronal basis of cannabis-induced developmental deficits in the central nervous system. Through their studies, they hope to identify organizing principles of endocannabinoid signaling in the developing brain with particular emphasis on the roles of endocannabinoids in establishing neuronal diversity and connectivity patterns. Current Research topics include:

i) Developmental functions of endocannabinoid signaling during corticogenesis,

ii) Context-dependent assembly of endocannabinoid signaling networks,

iii) Genetic and epigenetic factors controlling neuronal network formation,

iv) Developmental consequences of maternal cannabis smoking,

v) Endocannabinoid signaling in aging and Alzheimer's disease,

vi) Novel cannabinoid receptors.

For more information go to http://neuroseries.info.nih.gov
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NLM Title: Molecular dissection of cannabis sensitivity in the developing brain / Tibor Harkany.
Series: Neuroscience seminar series
Author: Harkany, Tibor.
National Institutes of Health (U.S.),
Publisher:
Other Title(s): Neuroscience seminar series
Abstract: (CIT): The Harkany lab focuses on understanding the developmental organization and functions of the endocannabinoid system by using a combination of molecular genetics, neuroimaging, neuroanatomy and electrophysiology approaches. Besides focusing on physiological developmental programs controlled by endocannabinoid signaling during corticogenesis, substantial resources are dedicated to elucidating the neuronal basis of cannabis-induced developmental deficits in the central nervous system. Through their studies, they hope to identify organizing principles of endocannabinoid signaling in the developing brain with particular emphasis on the roles of endocannabinoids in establishing neuronal diversity and connectivity patterns.
Subjects: Brain--drug effects
Brain--growth & development
Cannabinoids--pharmacology
Neurogenesis--drug effects
Receptors, Cannabinoid--metabolism
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: QV 77.7
NLM ID: 101609766
CIT Live ID: 12707
Permanent link: https://videocast.nih.gov/launch.asp?17921