BEGIN:VCALENDAR VERSION:2.0 PRODID:VideoCast CALSCALE:GREGORIAN METHOD:PUBLISH BEGIN:VEVENT SUMMARY:Marathons for T Cells: How They Keep on Killing DTSTART:20220615T190000Z DTEND:20220615T200000Z DTSTAMP:20220621T214300Z UID:Videocast--44268 LOCATION:https://videocast.nih.gov/watch=44268 DESCRIPTION:Gillian Griffiths\, Ph.D.\, Professor of Cell Biology and Immunology\, University of Cambridge\; Director\, Cambridge Institute for Medical Research\nThis WALS talk is jointly sponsored with the IIG. Dr. Griffiths is a Wellcome Trust Principal Research Fellow and a professor of immunology and cell biology at Cambridge Institute for Medical Research. For this lecture\, Dr. Griffiths will focus on the cell biology that underlies the remarkable ability of cytotoxic T lymphocytes to act as serial killers\, with individual cells providing sustained killing in response to cancer or virally infected targets. She will describe a screen that picked up genes that are required for sustained killing and revealed an unexpected role for mitochondria as homestatic regulators of CTL killing. She then will describe work by a former NIH-OxCam student that reveals an (again unexpected) role for transcription during killing. \n\nFor more information go to 'https://oir.nih.gov/wals'>https://oir.nih.gov/wals X-ALT-DESC;FMTTYPE=text/html:\n\n
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