BEGIN:VCALENDAR VERSION:2.0 PRODID:VideoCast CALSCALE:GREGORIAN METHOD:PUBLISH BEGIN:VEVENT SUMMARY:Genetic modifiers: Lessons from Nervous System Disorders (Day 2) DTSTART:20210922T140000Z DTEND:20210922T180000Z DTSTAMP:20210923T184000Z UID:Videocast--42419 LOCATION:https://videocast.nih.gov/watch=42419 DESCRIPTION:NIH Blueprint\nThis workshop will bring together a diverse group of researchers with expertise in genetics\, genomics\, neurology\, pathophysiology\, and preclinical translation. Understanding genetic factors that modify the onset\, progression or severity of diseases can lead to novel therapeutics\, facilitate clinical trial design\, and enable precision medicine. The purpose of this workshop is to promote collaborations\, confront challenges and highlight successful strategies for genetic modifier discovery\, validation\, characterization\, and clinical implementation as part of the NIH Blueprint mission to foster transformative discoveries in neuroscience.Day 1: Modifier discovery in human cohorts and model systems\, resources available and successful analytical approachesDay 2: Validation and characterization of modifiers\, determining mechanisms of disease modification and mapping modifier pathwaysDay 3: Clinical applications of modifiers as therapeutic targets\, in design of clinical trials and in precision medicine\n\nFor more information go to 'https://event.roseliassociates.com/genetic-modifiers-workshop/'>https://event.roseliassociates.com/genetic-modifiers-workshop/ X-ALT-DESC;FMTTYPE=text/html:\n\n
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