BEGIN:VCALENDAR VERSION:2.0 PRODID:VideoCast CALSCALE:GREGORIAN METHOD:PUBLISH BEGIN:VEVENT SUMMARY:Monocyte Heterogeneity: Implications for Cancer DTSTART:20171129T211500Z DTEND:20171129T221500Z DTSTAMP:20171120T205000Z UID:Videocast--23471 LOCATION:https://videocast.nih.gov/watch=23471 DESCRIPTION:Catherine “Lynn” Hedrick\, Ph.D.\, Professor\, Division of Inflammation Biology\, La Jolla Institute for Allergy and Immunology\nImmunonology IG Seminar \n\nMonocytes are key cells that drive the rapid innate immune response. We discovered that a subset of monocytes\, nonclassical monocytes (CD14dim in humans and Ly6C- in mice)\, function in the vasculature to recognize metastasizing tumor cells. Once these cells recognize tumor cells\, they orchestrate the killing of these cells to prevent metastasis. This presentation will discuss how nonclassical monocytes regulate tumor cell killing\, and will discuss the possible use of nonclassical monocytes in cancer immunotherapy. X-ALT-DESC;FMTTYPE=text/html:\n\n
\n