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Genetics of Aging Phenotypes over the Life Course: A Population Perspective

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Air date: Thursday, December 4, 2014, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 253, (46 Live, 207 On-demand)
Category: Geroscience
Runtime: 00:59:56
Description: The Trans-NIH GeroScience Interest Group (GSIG) cordially invites you to its fall seminar, featuring Dr. Joanne Murabito. Dr. Murabito is Director of the Clinic at the Framingham Heart Study, and she is an Associate Professor of Medicine at Boston University School of Medicine. Dr. Murabito’s research goals have focused on aging and reproductive traits in the Framingham Heart study and beyond. Specifically, her research program focuses on using the tools of epidemiology and high-throughput genetic platforms to better understand the natural history of aging and to detect novel pathways and mechanisms for aging-related traits. Studies in her laboratory encompass analysis of genome-wide association studies of aging phenotypes in human population samples using common and rare variant platforms; and investigation of determinants of healthy aging in the Framingham population. Dr. Murabito’s current projects include the epidemiology of centenarian experience in Framingham, physical activity and function, and biomarkers of frailty. She leads several international consortia dedicated to uncovering genes for aging-related traits, including age at menarche, age at natural menopause, and longevity. She collaborates with scientists at the Jackson Laboratory Nathan Shock Center of Excellence in the Basic Biology of Aging to further identify the functional relevance of human association findings. Dr. Murabito is keenly interested in how to reach older participants through novel technologies and use those technologies to maintain health. Dr. Murabito’s research has demonstrated that multiple genetic loci underlie reproductive aging, which are associated with many downstream aging-related disorders including obesity, DNA damage and repair and immune function.

The GeroScience Interest Group (GSIG) was formed to enhance opportunities for discussion of the intersection between the biology of aging and the biology of disease and conditions that are of interest across ICs. It is focused on basic biology, but with a longer view towards translation. If you are interested in learning more, please visit the GSIG web site http://sigs.nih.gov/geroscience/Pages/default.aspx.
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NLM Title: Genetics of aging phenotypes over the life course : a population perspective / Dr. Joanne Murabito ; Geroscience Interest Group.
Author: Murabito, Joanne.
National Institutes of Health (U.S.). Geroscience Interest Group,
Publisher:
Abstract: (CIT): The Trans-NIH GeroScience Interest Group (GSIG) cordially invites you to its fall seminar, featuring Dr. Joanne Murabito. Dr. Murabito is Director of the Clinic at the Framingham Heart Study, and she is an Associate Professor of Medicine at Boston University School of Medicine. Dr. Murabito's research goals have focused on aging and reproductive traits in the Framingham Heart study and beyond. Specifically, her research program focuses on using the tools of epidemiology and high-throughput genetic platforms to better understand the natural history of aging and to detect novel pathways and mechanisms for aging-related traits. Studies in her laboratory encompass analysis of genome-wide association studies of aging phenotypes in human population samples using common and rare variant platforms; and investigation of determinants of healthy aging in the Framingham population. Dr. Murabito"s current projects include the epidemiology of centenarian experience in Framingham, physical activity and function, and biomarkers of frailty. She leads several international consortia dedicated to uncovering genes for aging-related traits, including age at menarche, age at natural menopause, and longevity. She collaborates with scientists at the Jackson Laboratory Nathan Shock Center of Excellence in the Basic Biology of Aging to further identify the functional relevance of human association findings. Dr. Murabito is keenly interested in how to reach older participants through novel technologies and use those technologies to maintain health. Dr. Murabito's research has demonstrated that multiple genetic loci underlie reproductive aging, which are associated with many downstream aging-related disorders including obesity, DNA damage and repair and immune function. The GeroScience Interest Group (GSIG) was formed to enhance opportunities for discussion of the intersection between the biology of aging and the biology of disease and conditions that are of interest across ICs. It is focused on basic biology, but with a longer view towards translation.
Subjects: Aging--genetics
Cohort Studies
Longevity--genetics
Menopause--genetics
Phenotype
Publication Types: Lectures
Webcasts
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NLM Classification: WT 104
NLM ID: 101649917
CIT Live ID: 15230
Permanent link: https://videocast.nih.gov/launch.asp?18760