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Molecular Mechanisms Regulating Mammalian Aging

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Air date: Thursday, March 28, 2013, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 542, (63 Live, 479 On-demand)
Category: Geroscience
Runtime: 00:59:37
Description: The Geroscience Interest Group (GSIG) cordially invites you to the seminar listed above. Dr. Finkel is Chief of the Center for Molecular Medicine in the Division of Intramural Research at the National Heart, Lung, and Blood Institute. Dr. Finkel’s lab investigates the role of cellular metabolism and oxidative stress in aging and age-related diseases. His research has included studies on oxidative homeostasis in stem cell biology, cellular senescence as a model for aging, the role of autophagy in age-related diseases, and interrogating pathways in model organisms to understand their role in mammalian aging. Dr. Finkel is Editor-in-Chief of Drug Discovery Today-Disease Mechanisms and Associate Editor of Circulation Research.

Publications relevant to his seminar:

Narayan, N., Lee, I.H., Borenstein, R., Sun, J., Wong, R., Tong, G., Fergusson, M.M., Liu, J., Rovira, I.I., Cheng, H-L., Wang, G., Gucek, M., Lombard, D., Alt, F.W., Sack, M.N., Murphy, E., Cao, L., and Finkel, T. (2012). The NAD-dependent deacetylase SIRT2 is required for programmed necrosis. Nature, 492: 199-204

Finkel, T, Deng, C. and Mostoslavasky (2009) Recent progress in the biology and physiology of sirtuins. Nature, 460: 587-591.

The Geroscience Interest Group (GSIG) is a newly formed trans-NIH group aimed at enhancing opportunities for discussion of the intersection between the biology of aging and the biology of diseases and conditions that are of interest across ICs. It is focused on basic biology, but with a longer view towards translation. If you are interested in learning more, please visit the GSIG web site (http://sigs.nih.gov/geroscience/Pages/default.aspx).
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NLM Title: Molecular mechanisms regulating mammalian aging / Dr. Toren Finkel ; Geroscience Interest Group (GSIG).
Author: Finkel, Toren.
National Institutes of Health (U.S.). Geroscience Interest Group,
Publisher:
Abstract: (CIT): The Geroscience Interest Group (GSIG) cordially invites you to the seminar listed above. Dr. Finkel is Chief of the Center for Molecular Medicine in the Division of Intramural Research at the National Heart, Lung, and Blood Institute. Dr. Finkel's lab investigates the role of cellular metabolism and oxidative stress in aging and age-related diseases. His research has included studies on oxidative homeostasis in stem cell biology, cellular senescence as a model for aging, the role of autophagy in age-related diseases, and interrogating pathways in model organisms to understand their role in mammalian aging. Dr. Finkel is Editor-in-Chief of Drug Discovery Today-Disease Mechanisms and Associate Editor of Circulation Research. Publications relevant to his seminar: Narayan, N., Lee, I.H., Borenstein, R., Sun, J., Wong, R., Tong, G., Fergusson, M.M., Liu, J., Rovira, I.I., Cheng, H-L., Wang, G., Gucek, M., Lombard, D., Alt, F.W., Sack, M.N., Murphy, E., Cao, L., and Finkel, T. (2012). The NAD-dependent deacetylase SIRT2 is required for programmed necrosis. Nature, 492: 199-204 Finkel, T, Deng, C. and Mostoslavasky (2009) Recent progress in the biology and physiology of sirtuins. Nature, 460: 587-591. The Geroscience Interest Group (GSIG) is a newly formed trans-NIH group aimed at enhancing opportunities for discussion of the intersection between the biology of aging and the biology of diseases and conditions that are of interest across ICs. It is focused on basic biology, but with a longer view towards translation.
Subjects: Aging--pathology
Aging--physiology
Autophagy--physiology
Oxidative Stress--physiology
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: WT 104
NLM ID: 101607220
CIT Live ID: 12549
Permanent link: https://videocast.nih.gov/launch.asp?17876