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From Germline Genetics to Function: Making Sense of Genome-Wide Association Studies for Pancreatic Cancer Risk

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Air date: Friday, March 9, 2018, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 171, (104 Live, 67 On-demand)
Category: NIH Director's Seminars
Runtime: 00:57:14
Description: NIH Directors Seminar Series

Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States and the seventh world-wide. This seminar will discuss results from genome-wide association studies (GWAS), conducted within the NCI-led Pancreatic Cancer Cohort Consortium. This collaborative effort has identified over 20 common pancreatic cancer risk loci. Genomic and functional characterization of a subset of these loci will be presented. These examples highlight different molecular mechanisms underlying cancer risk and genes found to be important for a wide range of processes including telomere maintenance, RNA surveillance and pancreatic development and homeostasis.
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Author: Laufey Amundadottir, Ph.D., Senior Investigator, Laboratory of Translational Genomics, NCI, NIH
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CIT Live ID: 27321
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