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Dissection of the neuronal circuits and synapses that mediate the effects of drugs of abuse

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Air date: Friday, February 24, 2017, 12:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 91, (52 Live, 39 On-demand)
Category: NIH Director's Seminars
Runtime: 01:01:29
Description: Director's Seminar Series

Research in the laboratory headed by Dr. Alvarez is aimed at identifying the neuronal circuits that mediate and regulate reward-motivated and compulsive behaviors. The laboratory has focused on the behaviors toward substance of abuse, such as cocaine and ethanol, in addition to consummatory behaviors towards natural rewards like food and water. Dr. Alvarez pursues an integrative approach that includes the use of electrophysiology, 2-photon laser scanning microscopy and fast-scanning cyclic voltammetry for dopamine detection together with behavioral testing and in vivo manipulation of circuit activity using optogenetic and chemogenetic tools.
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NLM Title: Dissection of the neuronal circuits and synapses that mediate the effects of drugs of abuse / Veronica A. Alvarez.
Author: Alvarez, Veronica A.
National Institutes of Health (U.S.),
Publisher:
Abstract: (CIT): Director's Seminar Series. Research in the laboratory headed by Dr. Alvarez is aimed at identifying the neuronal circuits that mediate and regulate reward-motivated and compulsive behaviors. The laboratory has focused on the behaviors toward substance of abuse, such as cocaine and ethanol, in addition to consummatory behaviors towards natural rewards like food and water. Dr. Alvarez pursues an integrative approach that includes the use of electrophysiology, 2-photon laser scanning microscopy and fast-scanning cyclic voltammetry for dopamine detection together with behavioral testing and in vivo manipulation of circuit activity using optogenetic and chemogenetic tools.
Subjects: Brain--physiopathology
Compulsive Behavior--physiopathology
Dopamine
Substance-Related Disorders--physiopathology
Publication Types: Lectures
Webcasts
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Caption Text: Download Caption File
NLM Classification: WM 270
NLM ID: 101702176
CIT Live ID: 21867
Permanent link: https://videocast.nih.gov/launch.asp?22151