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What Doesn’t Kill you Makes you Fatter: Neurobiological Mechanisms Underlying Effects of Nicotine on Addiction and Appetite

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Air date: Wednesday, March 28, 2012, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 376, (120 Live, 256 On-demand)
Category: WALS - Wednesday Afternoon Lectures
Runtime: 01:08:04
Description: We all know people who smoke and have trouble quitting. People report that they smoke for different reasons including the desire to control their appetite, as a way to manage depression or anxiety or just because they relapse when they try to quit. It is now clear that nicotine is critical for both tobacco addiction as well as the other behavioral changes that occur from smoking. Nicotine hijacks receptors throughout the brain that normally respond to the neurotransmitter acetylcholine. There are many different types of these receptors that are found in brain areas important for reward and addiction, anxiety, depression and appetite. Recent studies have identified the molecules and brain areas responsible for many of these nicotine-induced behaviors. These findings have resulted in new ways to think about and treat smoking addiction, and have helped us understand more about the molecules and circuits in the brain that normally use the neurotransmitter acetylcholine.

The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

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NLM Title: What doesn"t kill you makes you fatter : neurobiological mechanisms underlying effects of nicotine on addiction and appetite [electronic resource] / Marina Picciotto.
Series: Wednesday afternoon lecture series
Author: Picciotto, Marina.
National Institutes of Health (U.S.)
Publisher:
Other Title(s): Wednesday afternoon lecture series
Abstract: (CIT): We all know people who smoke and have trouble quitting. People report that they smoke for different reasons including the desire to control their appetite, as a way to manage depression or anxiety or just because they relapse when they try to quit. It is now clear that nicotine is critical for both tobacco addiction as well as the other behavioral changes that occur from smoking. Nicotine hijacks receptors throughout the brain that normally respond to the neurotransmitter acetylcholine. There are many different types of these receptors that are found in brain areas important for reward and addiction, anxiety, depression and appetite. Recent studies have identified the molecules and brain areas responsible for many of these nicotine-induced behaviors. These findings have resulted in new ways to think about and treat smoking addiction, and have helped us understand more about the molecules and circuits in the brain that normally use the neurotransmitter acetylcholine.
Subjects: Appetite--drug effects
Behavioral Symptoms--etiology
Brain--drug effects
Nicotine--adverse effects
Obesity--etiology
Tobacco Use Disorder--complications
Publication Types: Lectures
Webcasts
Download: To download this event, select one of the available bitrates:
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Caption Text: Download Caption File
NLM Classification: QV 137
NLM ID: 101585218
CIT Live ID: 10517
Permanent link: https://videocast.nih.gov/launch.asp?17194

 

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