||Neuroscience Seminar Series
Dr. Lewis began his scientific career working with James Hudspeth at the California Institute of Technology characterizing the ionic conductances in hair cells, and then went to work with Mike Cahalan at University of California, Irvine, where he began studying ion channels in T lymphocytes. He started his own laboratory at Stanford University where he continued working on T lymphocytes, and began focusing his attention on the mechanisms of capacitive calcium entry or store-operated channels, a type of calcium channel that serves essential functions from secretion and motility to gene expression and cell growth. His laboratory has made fundamental contributions to our understanding of these store-operated channels, including identification of subunits responsible for channel formation, as well as the transduction of the ER depletion signal to the plasma membrane.
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