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Gridlock on the Genomic Beltway: How Epigenetic Gene Silencing Shapes our Cellular Phenotypes

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Air date: Wednesday, October 14, 2009, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Views: Total views: 110 * This only includes stats from October 2011 and forward.
Category: WALS - Wednesday Afternoon Lectures
Runtime: 00:58:26
Description: Dr. Rauscher's research at Wistar focuses on the molecular genetics of cancer. In particular, he is interested in the structure-function aspects of tumor suppressor and oncogene proteins, mechanisms of transcriptional regulation, transcriptional control of cellular differentiation programs and organogenesis.

Several years ago, he and his research team described the function of the WT1 gene that, when mutated, causes Wilms' Tumor. More recently, Dr. Rauscher and his team discovered BAP1, a gene encoding an enzyme that helps regulate levels of BRCA1 and is involved in the development of breast and lung cancers.

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
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NLM Title: Gridlock on the genomic beltway : how epigenetic gene silencing shapes our cellular phenotypes / Frank J. Rauscher III.
Author: Rauscher, F J.
National Institutes of Health (U.S.)
Subjects: Cell Differentiation--physiology
Gene Silencing--physiology
Genome, Human--genetics
Publication Types: Lectures
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NLM Classification: QU 475
NLM ID: 101518972
CIT Live ID: 7897
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