NIH VideoCast - Antigen Presenting Cell Dysregulation as a Mechanism Underlying Immune Evasion by Helminth Parasites

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Antigen Presenting Cell Dysregulation as a Mechanism Underlying Immune Evasion by Helminth Parasites

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Air date:	Wednesday, May 6, 2009, 4:15:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 118 * This only includes stats from October 2011 and forward.
Category:	Immunology
Runtime:	00:57:17
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	The interests of Roshanak Tolouei Semnani have revolved around dendritic cells and their role in directing specific T cell responses. As a graduate student at the University of Chicago, her work involved the role of co-stimulatory molecules in the T cell differentiation and activation process. Since coming to the NIH, her work has focused on the host parasite interface. She has established the importance of dendritic cell dysfunction in mediating the profound T cell hyporesponsiveness seen in parasitic helminth infection and has helped define many of the underlying mechanisms involved in this alteration of APC dysfunction. She has clearly defined novel mechansims by which parasitic human pathogens evade the host immune response thereby ensuring their continued survival and longevity. Originally from Iran, Roshanak is currently a Staff Scientist in the Laboratory of Parasitic Diseases (LPD). She has already received many local awards for her work on human dendritic cells as well as several "mentoring" awards for her guidance of students in the LPD. For more information, visit The Immunology Interest Group

NLM Title:	Antigen presenting cell dysregulation as a mechanism underlying immune evasion by helminth parasites / Roshanak Tolouei Semnani.
Author:	Semnani, Roshanak Tolouei. National Institutes of Health (U.S.). Immunology Interest Group.
Publisher:
Abstract:	(CIT): The interests of Roshanak Tolouei Semnani have revolved around dendritic cells and their role in directing specific T cell responses. As a graduate student at the University of Chicago, her work involved the role of co-stimulatory molecules in the T cell differentiation and activation process. Since coming to the NIH, her work has focused on the host parasite interface. She has established the importance of dendritic cell dysfunction in mediating the profound T cell hyporesponsiveness seen in parasitic helminth infection and has helped define many of the underlying mechanisms involved in this alteration of APC dysfunction. She has clearly defined novel mechansims by which parasitic human pathogens evade the host immune response thereby ensuring their continued survival and longevity. Originally from Iran, Roshanak is currently a Staff Scientist in the Laboratory of Parasitic Diseases (LPD). She has already received many local awards for her work on human dendritic cells as well as several "mentoring" awards for her guidance of students in the LPD.
Subjects:	Antigens, Helminth--immunology Helminthiasis--immunology
Publication Types:	Lecture Webcast
NLM Classification:	WC 800
NLM ID:	101507192
CIT Live ID:	7458
Permanent link:	https://videocast.nih.gov/watch=7458

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