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Neurotransmitter Transporters: Structure, Function and Regulation
Monday, May 3, 2004,
12:00:00 PM Time displayed is Eastern Time, Washington DC Local
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Neurotransmitter transporters present on the plasma membrane contribute to the clearance and recycling of neurotransmitters and can have a profound impact on the extent of receptor activation during neuronal signaling. Dr. Amara lab’s major research efforts have focused on the structure, regulation and cellular physiology of two families of sodium-dependent neurotransmitter transporters: the biogenic amine and the excitatory amino acid carriers. The dopamine, norepinephrine and serotonin transporters are well-established targets for addictive drugs including cocaine and amphetamines, and for therapeutic antidepressants.