NIH VideoCast - Therapeutic Opportunities in Glycoscience

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Therapeutic Opportunities in Glycoscience

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Air date:	Wednesday, October 21, 2020, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local
Views:	Total views: 931 (453 Live, 478 On-demand)
Category:	WALS - Wednesday Afternoon Lectures
Runtime:	01:04:46
Closed captioning:	Check box to display CC outside of the video Note: You can drag the captioning window around and resize it
Description:	NIH Wednesday Afternoon Lecture Cell surface glycans constitute a rich biomolecular dataset that drives both normal and pathological processes. Their “readers” are glycan-binding receptors that can engage in cell-cell interactions and cell signaling. Our research focuses on mechanistic studies of glycan/receptor biology and applications of this knowledge to new therapeutic strategies. Our recent efforts center on pathogenic glycans in the tumor microenvironment and new therapeutic modalities based on the concept of targeted degradation.

NLM Title:	Therapeutic opportunities in glycoscience / Carolyn R. Bertozzi.
Author:	Bertozzi, Carolyn R. National Institutes of Health (U.S.),
Publisher:
Abstract:	(CIT): NIH Wednesday Afternoon Lecture Cell surface glycans constitute a rich biomolecular dataset that drives both normal and pathological processes. Their "readers" are glycan-binding receptors that can engage in cell-cell interactions and cell signaling. Our research focuses on mechanistic studies of glycan/receptor biology and applications of this knowledge to new therapeutic strategies. Our recent efforts center on pathogenic glycans in the tumor microenvironment and new therapeutic modalities based on the concept of targeted degradation.
Subjects:	Autophagy--drug effects Glycomics Lysosomes--genetics Lysosomes--metabolism Neoplasms--drug therapy Neoplasms--genetics
Publication Types:	Lecture Webcast

NLM Classification:	QZ 267
NLM ID:	101773047
CIT Live ID:	38867
Permanent link:	https://videocast.nih.gov/watch=38867

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