Fevers, Genes, and Histories: Adventures in the Genomics of Inflammation

 


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Air date: Wednesday, November 18, 2009, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
Category: Wednesday Afternoon Lectures
Description: Fever is a fundamental sign of inflammation, and hereditary disorders that present with recurrent fever provide a unique opportunity to understand the human biology of inflammation. Stimulated by encounters with patients suffering from hereditary recurrent fevers and utilizing the tools of modern genetics and genomics, it has been possible to identify new genes, gene families, and biochemical pathways that control inflammation, and to discover new meaning for genes and proteins already in the inflammatory lexicon. In some cases, these discoveries have not only given molecular explanations and suggested targeted therapies for the patients we see today, but have shed light on the histories of human populations and their possible evolving interactions with microbial pathogens.

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Author: Dr. Daniel Kastner
Runtime: 60 minutes
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CIT File ID: 15441
CIT Live ID: 8225
Permanent link: http://videocast.nih.gov/launch.asp?15441