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Drs. Berg (Director, NIGMS), Lewis (Director, Div Cell Biology and Biophysics, NIGMS), and Preusch (Program Director for the PSI:Biology Program) will discuss the recently released RFAs that will establish the PSI:Biology Network. They will take Q&A from viewers via telephone and email. The PSI:Biology program is a new direction for the NIGMS supported Protein Structure Initiative that will establish a series of Centers for High-Throughput Structure Determination, Centers for Membrane Protein Structure Determination, and Centers for High-Throughput Enabled Structural Biology Partnerships.