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The interest of Dr. Khodakhah's laboratory is to understand the role of the cerebellum and basal ganglia in motor function and in movement and neurologic disorders. Of particular interest to their lab is not only to understand the role of each structure in motor control, but also the manner in which they communicate to coordinate and complement each other. They approach these questions from both basic science and clinical perspectives. They use a combination of techniques, from behavioral studies to optogenetics and electrophysiology (both in vitro and in vivo). Their studies take advantage of normal and transgenic animal models