From Transcript to Target: Integrating RNAi into the Analysis of Cancer Gene Function and Anti-cancer Drug Development (NIH-Only) |
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| Air date: | Tuesday, October 27, 2009, 8:00:00 AM Time displayed is Eastern Time, Washington DC Local |
| Category: | NCI CCR Grand Rounds (NIH Only) |
| Description: | Dr. Caplen obtained her Ph.D. from the University of London (Kings College Hospital Medical School) for studies on the genetics of type I diabetes and its complications. Dr. Caplen's postdoctoral training began at St. Mary's Hospital Medical School, Imperial College, where she focused on the development of gene therapy approaches for cystic fibrosis (CF) during which she was involved in some of the first pre-clinical and clinical studies of cationic lipid mediated gene therapy for CF. In 1996, Dr. Caplen came to the National Human Genome Research Institute (NHGRI) at NIH as a visiting fellow, where she initially conducted studies investigating hybrid viral vector systems for the delivery of genes. It was while at NHGRI that Dr. Caplen developed a research interest in the newly identified gene silencing mechanism, RNA interference (RNAi) leading to her studies that help establish the presence of RNAi in mammalian cells. Dr. Caplen joined CCR, NCI, in 2004 as a senior scientist, where she heads the Gene Silencing Section initially within the CCR Office of Science and Technology Partnerships and more recently within the Genetics Branch.
NCI’s Center for Cancer Research (CCR) Grand Rounds is a weekly lecture series addressing current research in clinical and molecular oncology. Speakers are leading national and international researchers and clinicians proposed by members of the CCR Grand Rounds Planning Committee and others within the CCR community and approved by the CCR Office of the Director. Lectures occur every Tuesday from 8:00 to 9:00 a.m. in Lipsett Amphitheater in the Clinical Center building on the NIH campus September through July with exceptions around holidays and major cancer meetings. The lecture schedule is posted on various calendars of events, including at the following link: http://www.bethesdatrials.cancer.gov/health-care-professionals/grand-rounds.aspx |
| Author: | Natasha Caplen, Ph.D. |
| Runtime: | 60 minutes |
| CIT File ID: | 15388 |
| CIT Live ID: | 8115 |
| Permanent link: | http://videocast.nih.gov/launch.asp?15388 |