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Beta-Arrestins: Traffic Cops of Cell Signaling

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Air date: Wednesday, June 19, 2002, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: Wednesday Afternoon Lectures
Runtime: 01:09:40
Description: The NIH Director's Wednesday Afternoon Lecture Series.

The last few years have witnessed a remarkable expansion in the appreciation of the diversity of roles played by the beta-arrestins in regulating the function and trafficking of heptahelical (G protein-coupled) receptors. Originally discovered as molecules that desensitize such receptors, the roles of beta-arrestins have expanded to include acting as signaling adaptors or intermediates that recruit other key molecules to the receptors in an agonist-regulated fashion.

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Robert J. Lefkowitz, M.D
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Author: Robert Lefkowitz, M.D., Duke University Medical Center
Rights: This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
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CIT Live ID: 959
Permanent link: http://videocast.nih.gov/launch.asp?10270

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