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Bacteria communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process, called quorum sensing, enables bacteria to successfully infect and cause disease host organisms. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the basis of new therapies to be used as antibiotics.
Intra- and inter-species cell-to-cell communication in bacteria [electronic resource] / Bonnie Bassler.
Series:
NIH director's Wednesday afternoon lecture series. DeWitt Stetten, Jr. lecture
Author:
Bassler, Bonnie L. National Institutes of Health (U.S.)
Publisher:
[Bethesda, Md. : National Institutes of Health, 2009]
Other Title(s):
NIH director's Wednesday afternoon lecture series. DeWitt Stetten, Jr. lecture
Abstract:
(CIT): Bacteria communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process, called quorum sensing, enables bacteria to successfully infect and cause disease host organisms. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the basis of new therapies to be used as antibiotics. The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
Subjects:
Bacteria--chemistry Bacterial Physiological Phenomena Cell Communication