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Chance or Necessity: The CD4+ Autoreactive T Cell in Type 1 Diabetes

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Air date: Wednesday, April 16, 2008, 4:15:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: Immunology
Runtime: 01:09:09
Description: Dr. Nepom has been at the University of Washington in Seattle for most of his career, and he is now also the director of the Benaroya Research Institute at Virginia Mason. Over the years, he has contributed much to our general understanding of the structure and function MHC class II molecules, and he has specifically focused on their link to autoimmune diseases such as type 1 diabetes. His group has also designed MHC class II multimers, and used these as tools to study human autoreactive T cells. Such measurements of autoantigen-specific T cells are particularly important in the context of measuring specificity and efficacy of new immunomodulatory treatments for autoimmune diseases.

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NLM Title: Chance or necessity : the CD4+ autoreactive T cell in type 1 diabetes [electronic resource] / Gerry Nepom.
Series: CD4+ autoreactive T cell in type 1 diabetes
Author: Nepom, Gerald T.
National Institutes of Health (U.S.). Immunology Interest Group.
Publisher:
Other Title(s): CD4+ autoreactive T cell in type 1 diabetes
Abstract: (CIT): Dr. Nepom has contributed much to our general understanding of the structure and function of MHC class II molecules, and he has specifically focused on their link to autoimmune diseases such as type 1 diabetes. His group has also designed MHC class II multimers, and used these as tools to study human autoreactive T cells. Such measurements of autoantigen-specific T cells are particularly important in the context of measuring specificity and efficacy of new immunomodulatory treatments for autoimmune diseases.
Subjects: CD4-Positive T-Lymphocytes
Diabetes Mellitus, Type 1--immunology
Immunotherapy
Publication Types: Lectures
Webcasts
Download: To download this event, select one of the available bitrates:
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NLM Classification: WK 810
NLM ID: 101473091
CIT Live ID: 6147
Permanent link: http://videocast.nih.gov/launch.asp?14437