Skip Navigation


CIT can broadcast your seminar, conference or meeting live to a world-wide audience over the Internet as a real-time streaming video. The event can be recorded and made available for viewers to watch at their convenience as an on-demand video or a downloadable podcast. CIT can also broadcast NIH-only or HHS-only content.

Novel Study Designs for Treatment Strategies that Reflect Actual Clinical Practice

Loading video...

 
   
Air date: Friday, April 11, 2008, 10:00:00 AM
Time displayed is Eastern Time, Washington DC Local
Views:  
Category: Special
Runtime: 01:05:05
Description: OPASI ROUNDS Lecture Series

Novel Study Designs for Treatment Strategies that Reflect Actual Clinical Practice: Issues They Raise Regarding Implementation and Analysis.

Dr. Tsiatis will discuss actual clinical practice; clinicians make a series of treatment decisions over time on a given patient, where each decision depends on the progress of the patient up to that point. For example, decisions on whether to switch treatments, discontinue or augment therapy, or undertake surgical intervention may be made on the basis of patient outcomes such as laboratory measures, adverse events, physical characteristics, and prior treatment history. At key such decision points, there may be several treatment options, and there may be no consensus regarding which option is preferred. Most clinical trials focus on comparing treatment options at only a single point in time, where subsequent decisions on care of the participants are handled in the analysis according to the intention to treat principle. Consequently, such studies do not systematically attempt to identify the best series of options at each of several decision points over time.

The Office of Portfolio Analysis and Strategic Initiatives (OPASI) provides the National Institutes of Health (NIH) and its constituent Institutes and Centers (ICs) with the methods and information necessary to manage their large and complex scientific portfolios, identifies – in concert with multiple other inputs – important areas of emerging scientific opportunities or rising public health challenges, and assists in the acceleration of investments in these areas, focusing on those involving multiple ICs.
Debug: Show Debug
NLM Title: Novel study designs for treatment strategies that reflect actual clinical practice [electronic resource] / Anastasios Tsiatis.
Series: OPASI rounds lecture series
Author: Tsiatis, Anastasios A.
National Institutes of Health (U.S.)
Publisher:
Other Title(s): OPASI rounds lecture series
Abstract: (CIT): OPASI ROUNDS Lecture Series Novel Study Designs for Treatment Strategies that Reflect Actual Clinical Practice: Issues They Raise Regarding Implementation and Analysis. Dr. Tsiatis will discuss actual clinical practice; clinicians make a series of treatment decisions over time on a given patient, where each decision depends on the progress of the patient up to that point. For example, decisions on whether to switch treatments, discontinue or augment therapy, or undertake surgical intervention may be made on the basis of patient outcomes such as laboratory measures, adverse events, physical characteristics, and prior treatment history. At key such decision points, there may be several treatment options, and there may be no consensus regarding which option is preferred. Most clinical trials focus on comparing treatment options at only a single point in time, where subsequent decisions on care of the participants are handled in the analysis according to the intention to treat principle. Consequently, such studies do not systematically attempt to identify the best series of options at each of several decision points over time. The Office of Portfolio Analysis and Strategic Initiatives (OPASI) provides the National Institutes of Health (NIH) and its constituent Institutes and Centers (ICs) with the methods and information necessary to manage their large and complex scientific portfolios, identifies - in concert with multiple other inputs - important areas of emerging scientific opportunities or rising public health challenges, and assists in the acceleration of investments in these areas, focusing on those involving multiple ICs.
Subjects: Clinical Protocols
Evidence-Based Medicine
Patient Care Planning
Research Design
Publication Types: Lectures
Webcasts
Download: To download this event, select one of the available bitrates:
[384k]    How to download a Videocast
NLM Classification: W 84.7
NLM ID: 101473083
CIT Live ID: 6094
Permanent link: http://videocast.nih.gov/launch.asp?14425

 

Podcast information
Audio Podcasts   Video Podcasts
  Description Runtime     Description Runtime
Listen to the podcast Enhanced Audio Podcast 1:05:04   Watch the podcast Enhanced Video Podcast 1:05:04