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Dr. Nussenzweig pursues a combination of biochemical, molecular and genetic approaches to define the checkpoints that regulate B-cell development, antibody production and B-cell tolerance. A second area of interest is in dendritic cells.
His research interests range from the earliest phases of the B-cell pathway, including the commitment to becoming a B-cell through the completion of maturation. His ongoing work includes a focus on mechanisms of V(D)J recombination, somatic mutation, isotype switching, allelic exclusion and tolerance.
Switching on chromosome translocations [electronic resource] / Michel Nussenzweig.
Series:
NIH director's Wednesday afternoon lecture series
Author:
Nussenzweig, Michel. National Institutes of Health (U.S.)
Publisher:
[Bethesda, Md. : National Institutes of Health, 2006]
Other Title(s):
NIH director's Wednesday afternoon lecture series
Abstract:
(CIT): Dr. Nussenzweig pursues a combination of biochemical, molecular and genetic approaches to define the checkpoints that regulate B-cell development, antibody production and B-cell tolerance. A second area of interest is in dendritic cells. His research interests range from the earliest phases of the B-cell pathway, including the commitment to becoming a B-cell through the completion of maturation. His ongoing work includes a focus on mechanisms of V(D)J recombination, somatic mutation, isotype switching, allelic exclusion and tolerance.
Subjects:
Immunoglobulin Class Switching Translocation, Genetic
