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Switching on Chromosome Translocations

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Air date: Wednesday, April 19, 2006, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local
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Category: WALS - Wednesday Afternoon Lectures
Runtime: 00:57:21
Description: Dr. Nussenzweig pursues a combination of biochemical, molecular and genetic approaches to define the checkpoints that regulate B-cell development, antibody production and B-cell tolerance. A second area of interest is in dendritic cells. His research interests range from the earliest phases of the B-cell pathway, including the commitment to becoming a B-cell through the completion of maturation. His ongoing work includes a focus on mechanisms of V(D)J recombination, somatic mutation, isotype switching, allelic exclusion and tolerance.

For more information, visit
http://www.hhmi.org/research/investigators/nussenzweig.html

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.
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NLM Title: Switching on chromosome translocations [electronic resource] / Michel Nussenzweig.
Series: NIH director's Wednesday afternoon lecture series
Author: Nussenzweig, Michel.
National Institutes of Health (U.S.)
Publisher:
Other Title(s): NIH director's Wednesday afternoon lecture series
Abstract: (CIT): Dr. Nussenzweig pursues a combination of biochemical, molecular and genetic approaches to define the checkpoints that regulate B-cell development, antibody production and B-cell tolerance. A second area of interest is in dendritic cells. His research interests range from the earliest phases of the B-cell pathway, including the commitment to becoming a B-cell through the completion of maturation. His ongoing work includes a focus on mechanisms of V(D)J recombination, somatic mutation, isotype switching, allelic exclusion and tolerance.
Subjects: Immunoglobulin Class Switching
Translocation, Genetic
Publication Types: Lectures
Webcasts
Download: To download this event, select one of the available bitrates:
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NLM Classification: QS 677
NLM ID: 101289646
CIT Live ID: 4286
Permanent link: http://videocast.nih.gov/launch.asp?13181

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